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[H]N(C(=O)C([H])([H])C1=C(N([H])N=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1Cl)C(F)(F)F
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N1C([H])=C(N=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])O[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])N(N=C2C1=C([H])C([H])=C(O[H])C([H])=C1O[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
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[H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C2C(=O)C([H])([H])C(C2=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C(N([H])C([H])([H])C([H])([H])[H])=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C(N([H])C(=O)C2=C([H])C(=NN2C2=C([H])C([H])=C3C([H])=C(Cl)C([H])=C([H])C3=C2[H])C(F)(F)F)C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2C([H])=C(C#CC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])N([H])[H])C([H])=C([H])C2=C1[H]
[H]ON([H])C(=O)C1=C([H])C2=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2S1
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=NC2=C([H])C([H])=C(Cl)C([H])=C2C(=C1[H])C(=O)OC([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=N2)S(=O)(=O)C1=C([H])C([H])=C(S1)C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C([H])=NC2=C(N=C(N=C12)C#N)N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C(Br)=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(N([H])C([H])([H])C2=NC([H])=C([H])C([H])=C2[H])=C(C([H])=C1[N+]([O-])=O)[N+]([O-])=O)C([H])([H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C(O1)C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C(Cl)C([H])=C1C1=C([H])C(F)=C(F)C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(N([H])C3=NN4C(=C([H])C([H])=C4C4=C([H])C([H])=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C4[H])C([H])=N3)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O\N=C(/[H])C1=[N+](C([H])=C([H])N1C([H])([H])[H])C([H])([H])O[C@]([H])(C([H])([H])[H])C([H])([H])C#C[H]
[H]OC1=C(N([H])C2=N[S@](=O)N=C2N([H])[C@@]([H])(C2=C([H])C(=C(O2)C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N(C([H])([H])[H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])[H]
[H]O[C@@]1([H])C2=C(C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C([H])C(=C([H])C([H])=C2N=C1C([H])([H])C([H])([H])C([H])([H])[H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C2OC([H])([H])OC2=C([H])C(=C1[H])C1=C([H])C([H])=C2C(OC([H])=C(C3=C([H])N=C(C([H])=C3[H])N3C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C3([H])[H])C2=O)=C1[H]
[H]ON(C([H])=O)[C@]([H])([C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=NC([H])=C([H])S1)C([H])([H])C([H])([H])C([H])([H])\N=C(\N([H])[H])N([H])[N+]([O-])=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])N2C(=C1[H])C(OC(=O)C([H])([H])[H])=C(OC1=C([H])C([H])=C([H])C([H])=C21)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=NC2=C(N=C(N=C2N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[H])N1C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1Br
[H]N([H])C1=N[C@@](C2=C([H])C(=C([H])C([H])=C2F)C([H])([H])C(=O)C2=NC([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C(F)(F)C([H])([H])S1
CC[C@@H](CO)NC1=C(C=NC(NC2=CC(Cl)=CC(Cl)=C2)=N1)C(=O)NC1CCN(C)CC1
[H]C1=C(N=NN1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC1=C(C([H])=C([H])C2=C([H])C([H])=C([H])N=C12)C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C([H])([H])[C@@]2(C3=C(C([H])=C([H])C([H])=C3[H])C3=C2C([H])=C(Cl)C([H])=C3[H])S1(=O)=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N(C(=O)C([H])([H])C1=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(N([H])C(=O)C([H])([H])C(\[H])=C(/[H])[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(N([H])[H])[C@@]([H])(C2([H])[H])S(=O)(=O)C([H])([H])[H]
[H]ON(C([H])=O)[C@@]([H])(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(F)=C1[H])C([H])([H])N1C(=O)C([H])([H])[C@]([H])(C2=C3C(OC4=C3C([H])=C([H])C([H])=C4[H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(N(C3=NC([H])=C([H])C(=C23)C([H])([H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C(F)=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(S1)C1=C([H])C(C#CC2=NC(=C([H])C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(Cl)=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C2(C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C(Br)C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N3C(=O)C([H])([H])C4(C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3=O)C([H])([H])C2([H])[H])C(Br)=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C(=O)OC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])=C([H])C([H])=C12
[H]O[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@]([H])(N([H])C(=O)C1=C([H])N=C(N=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
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[H]N(C(=O)C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C(N1C([H])([H])[H])C([H])([H])C(=O)N(C1=C([H])C([H])=C(Cl)C(=C1Cl)C([H])([H])OC1=C2N=C(C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C(=O)O[H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O\N=C(\C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]([H])(N([H])C1=C(C([H])=NC([H])=C1[H])S(=O)(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])Cl)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])N(C(=O)C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
OC(=O)CCC1=CC=C(OCC2=C(Br)C=CC=C2)C=C1
[H]OC1=C(O[H])C([H])=C2C(OC([H])([H])[C@]([H])(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C2([H])[H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N=[N+]=[N-])C([H])=C1[H]
[H]C1=C(ON=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C(O[H])C(=O)C2=C([H])C(=C([H])C(N3C(=O)N([H])C([H])([H])C3=O)=C2O1)C([H])([H])[H]
[H]N1C(=O)S\C(=C(\[H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C1=O
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Cl.[O-][N+](=O)C1=CC=C(CN2CCC3(CCCC4=CC=CC=C34)CC2)C=C1
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[H]C1=C([H])C([H])=C(O1)C1=NN=C2N(C3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
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[H]OC1=C([H])C([H])=C([H])C([H])=C1C(=O)C(\[H])=C(/[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
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[H]N([H])S(=O)(=O)C1=NN(\C(S1)=N/C(=O)C([H])([H])[N+]1=C(C([H])=C(C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N=C(S1)C([H])([H])[H])C#CC1=C([H])C(F)=C([H])C(=C1[H])[N+]([O-])=O
[H]N(C1=NC([H])=C(N2C([H])=NC([H])=C12)C1=C([H])C([H])=NC([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])OC(=O)N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N(C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H]
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2Cl)C(=O)N([H])C2=NC(=C(S2)C([H])([H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C(F)C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(Br)C([H])=C2[C@@]([H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)SC1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]2(C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])N(C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(Cl)C(=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C1=C([H])C(O[H])=C(O[H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C(N([H])C([H])([H])[H])=C([H])C(N([H])C([H])([H])[H])=C1[H]
[H]ON([H])C(=O)C(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])[C@]([H])(OC(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])N(N=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C#CC1=C([H])C(N([H])C(=O)N([H])[C@]2([H])N=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3N(C2=O)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H])C([H])([H])C([H])([H])N1N=C([H])C(=C1[H])C([H])([H])[H]
[H]N(\C(=N/C#N)N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C([H])N(N=C2C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])SC(=O)C([H])([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N2C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=N1
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[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C2=C1C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C([H])=C([H])C(=NC2=N1)C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)[C@@]([H])(N1C(=NC2=C([H])C(F)=C(Cl)C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(OC(=C1C(=O)N1C2=C(C([H])=C3C([H])=C([H])N=C(N4C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C4([H])[H])C3=C2[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N([H])C1=C(C([H])=C([H])C([H])=C1[H])N(C1=C([H])C([H])=C(C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(Cl)=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C(N([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
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[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])=NC2=C([H])C([H])=C(C#CC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C1=O
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[H]N=C(N([H])[H])C1=C([H])C(OC2=C(N([H])C(=O)N([H])C([H])([H])[H])C([H])=C([H])C(OC3=C([H])C(=C([H])C([H])=C3[H])C(=N[H])N([H])[H])=N2)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)N2C([H])([H])[H]
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[H]N([H])C1=NC(N([H])[H])=C2C(=N1)N([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1Cl
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(O2)C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])OC1=C2C([H])=C([H])N([H])C2=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])N([H])[H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C1=NC2=C(SC3=C([H])C([H])=C(Cl)C([H])=C23)C(=O)N1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C(O1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]12C(=O)OC([H])([H])C1=C([H])[C@@]([H])(OC(=O)C(\[H])=C(/[H])\C(\[H])=C(/[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])OC(=O)C([H])([H])C1=C(N(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N(C(=O)C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])N(C1=O)[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C(C(OC2=C([H])C([H])=C([H])C([H])=C2Cl)=N1)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2S1(=O)=O
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N2C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C#CC([H])([H])N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(F)=C(F)C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C(F)C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(N2[C@]2([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]([H])(O[H])[C@]2([H])O[H])C2=C(C3=C(N2[H])C(O[H])=C([H])C([H])=C3[H])C2=C1C(=O)N(N([H])C([H])(C([H])([H])O[H])C([H])([H])O[H])C2=O
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C1=C(Cl)C(=C(Cl)C([H])=C1[H])C1=C([H])C2=C([H])N=C(N=C2N(C1=O)C([H])([H])[H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])C([H])([H])C([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)N2OC(=O)C(=C2C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(S[H])C([H])([H])[H])C([H])([H])SSC(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(N([H])C1=O)C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C1=NC(SC([H])([H])C2=C(F)C(F)=C([H])C([H])=C2[H])=NC2=C1N=C([H])C(=O)N2[H])C([H])([H])[H]
[H]N(C(=O)N1C(=O)N([H])C(=C(C(=O)OC([H])([H])C([H])([H])[H])[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(C(=O)OC([H])([H])[H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)\C(=C2/N([H])C3=C(C([H])=C([H])C([H])=C3[H])/C/2=N\OC(=O)C([H])([H])[H])C2=C([H])C([H])=C(Br)C([H])=C12
[H]\C(=C(\[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=NC2=C(N1C([H])([H])C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(OC2=C([H])C3=C(C([H])=C2C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C(C([H])=C(C(Cl)=C1[H])S(=O)(=O)N([H])[H])S(=O)(=O)N([H])[H]
[H]N([C@]([H])(C1=NC([H])([H])[C@]([H])(N1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C(=O)N([H])S1(=O)=O)S(=O)(=O)C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N(C1=NC(=NC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(=N1)N1C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C(C([H])=C(Cl)C([H])=C2[H])[N+]([O-])=O)C1=O
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(=C([H])C(Cl)=C1[H])N1N=C(C2=C([H])N=C(N([H])[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C12)C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(N([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4N=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])=O
[H]OC1=C([H])C([H])=C2C(O[C@]([H])(C([H])([H])C2([H])[H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]N([H])C1=N[C@@](C2=C([H])C([H])=C([H])C(F)=C12)(C1=C([H])C(=NC([H])=C1[H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=C([H])N=C1[H]
[H]O[C@@]1([H])C2=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C2O[C@]2(C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C3=C([H])C4=NON=C4C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N([H])C1=C(O[C@]([H])(C2=C(Cl)C([H])=C([H])C(F)=C2Cl)C([H])([H])[H])C([H])=C(C([H])=N1)C1=C([H])N(N=C1[H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=N1)C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C1=NC([H])=NC2=C1C([H])=C(C([H])=C2[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])OC(=O)C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N1C([H])=C(C2=C1C([H])=C([H])C(N([H])C(=O)C([H])([H])[H])=C2[H])C1=NC2=C(C#N)C([H])=NN2C(N([H])C2([H])C([H])([H])C2([H])[H])=C1[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@@]([H])(SC(=O)C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N([H])C(=NC(=O)C1=C([H])C([H])=C(O1)C1=C(C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])N([H])[H]
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[H]N(C(=O)C1=C(C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C2([H])[H]
CCN1CCC(CC1)NC1=CC2=C(NC(=O)C2=C(C2=NC3=CC(OC)=CC=C3N2)C2=CC=CC=C2)C=C1
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[H]ON([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])SC([H])=N1
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[H][C@]12CCC[C@]1(C[C@@H](C2)NC1CCOCC1OC)C(=O)N1CCC2=C(C1)C=C(C=N2)C(F)(F)F
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[H]C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C2N(N=C(C2=NC(=N1)C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=O)OC([H])([H])[H])[C@]2([H])O[C@@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
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[H]C1=C([H])C(C2=NN(C3=C2N=C(C([H])=C3N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2C([H])=NC([H])=C([H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C(=N/C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])\N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(O1)C1=C([H])C(=NC(SC([H])([H])C([H])([H])C(=O)N2C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])C2([H])[H])=N1)C(F)(F)F
NS(=O)(=O)C1=CC=C(C=C1)N1N=C(C=C1CO)C1=CC=CC=C1
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[H]N(C1=N\C(=C(\[H])C2=C([H])N([H])C3=NC([H])=C([H])C([H])=C23)C(=O)N1[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]OC1=C([H])C([H])=C2C(OC(=O)C3=C2C(=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])C([H])=C([H])[H])=C1C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N2C([H])([H])C3=C(C([H])=C(C([H])=C3[H])[N+]([O-])=O)C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(O[H])C(OC([H])([H])[H])=C2[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C1=NC2=C(N=C([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])O[H]
ClC1=CC=C(C=C1)N1CCN(CC1)C1CC[Si](C1)(C1=CC=CC=C1)C1=CC=CC=C1
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C1([H])[H])[C@@]([H])(N([H])C1=NC([H])=C([H])C(=N1)N1C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N(C(=O)C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
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[H]C1=C([H])C2=C(C([H])=C(N=C2C(=C1[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C2=NC([H])=C(C#N)C(=N2)C2=C([H])C([H])=C3N([H])C([H])=C([H])C3=C2[H])C([H])=C1[H]
[H]ON(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C#CC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]N1C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C([H])C([H])=C([H])C([H])=C4C(F)(F)F)C([H])([H])C3([H])[H])C([H])=C12
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C(N1[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])C1=C([H])N=C(S1)C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1[Se]C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]N1C(SC([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=NC2=C1C([H])=C([H])C(=C2[H])[N+]([O-])=O
[H]C1=C(C([H])=C2C([H])=C([H])C([H])=C([H])C2=N1)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C2=C(N([H])C([H])=C2[H])C([H])=C1[H])C1=C(C#N)C([H])=NC2=C1C([H])=C(S2)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(N=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2[H])C(=N1)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(Br)=C(OC([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C(Br)=C1[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=NN(N=N1)C1=C([H])C(F)=C([H])C(C#N)=C1[H]
[H]N(C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C(C(=O)N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C1=C([H])N(C([H])=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C1=NC(=NN2C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]S\C(=N/C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)[C@@]1([H])N(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2Cl)C(=O)N2C3=C(SC([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]([H])(OC([H])([H])[H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=NN([H])C(=N1)C(=O)OC([H])([H])[H]
[H]N1C(=O)S[C@]([H])(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC2=C(C([H])=C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C(C(=O)OC1([H])[H])C1=C([H])C([H])=C(F)C(F)=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C(=O)OC([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])N1C([H])=C([H])C2=C([H])C3=C(N=C([H])N=C3N([H])C3=C([H])C([H])=C([H])C(Br)=C3[H])C([H])=C12
[H]N([H])C1=NC(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])N([H])C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])N([H])C([H])([H])C(F)(F)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C([H])=C([H])C(=C3[H])N2C([H])=NC3=C(SC(=C3[H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C2=O)C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C([H])C([H])=C([H])N=C12)S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]N([H])C1=C([H])C(=C([H])C(=C1[H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)[C@]([H])(N(C(=O)C([H])([H])C1=C2S[C@]([H])(C([H])([H])[H])C([H])([H])C3=C2C(=C([H])C([H])=C3OC([H])([H])C2=C([H])C([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])=C4C([H])=C(C5=C([H])C([H])=C([H])C([H])=C5[H])C([H])([H])C([H])([H])[C@]4(C([H])=C([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(SC(=C2OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]C1=C(N(N=C1C(=O)N(C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(C#N)[C@]1([H])C(=O)N([H])C2=C([H])C([H])=C(Br)C([H])=C12
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CC1=CN=C(CNCC2(F)CCN(CC2)C(=O)C2=CC3=C(O2)C=CC=C3)C=C1
[H]OC1=C([H])C2=C(O[H])C(=C(C([H])=C2C(C(=O)N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1O[H])C([H])([H])[H])C1=C(O[H])C2=C([H])C(O[H])=C(O[H])C(C(=O)N([H])C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2C([H])=C1C([H])([H])[H]
[H]N([H])C1=C([H])C(=C2N=C(N([H])C2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C(C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N=C(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N=C(S1)C1=C([H])OC2=C(C([H])=C(C(OC(=O)C([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O)C([H])([H])[H]
CC(=O)N[C@@H](CC1=CC(F)=CC(F)=C1)[C@H](O)CNC1(CCCCC1)C1=CC=CS1
[H]N([H])S(=O)(=O)C1=C([H])N=C([H])C([H])=C1OC([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(=NC(=N1)N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(F)C([H])=C1[H])N([H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C2C([H])=[N+]3C(=C([H])C2=C([H])C([H])=C1OC([H])([H])[H])C1=C(C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C3([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@]2(C3=C([H])C([H])=C(OC([H])([H])C4=C([H])C([H])=C([H])N=C4C([H])([H])[H])C([H])=C3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])[C@@]1(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])C(=O)C([H])([H])C([H])([H])SSC([H])([H])C([H])([H])C(=O)N([H])C1=NN=C(S1)S(=O)(=O)N([H])[H]
[3H]C([3H])([3H])C([3H])([3H])CN1C2=C(NC(=N2)C2=CC=C(OCC(=O)NC3=CC=C(C=C3)C#N)C=C2)C(=O)N(CC([3H])([3H])C([3H])([3H])[3H])C1=O
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[H]C1=C([H])C(Cl)=C(Cl)C([H])=C1N(C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C#N)C(=N\C([H])([H])C1=C([H])C([H])=[N+]([O-])C([H])=C1[H])\N1C([H])([H])C([H])([H])C(=C2C3=C(C([H])=C(Br)C([H])=N3)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N(C(=O)[C@@]([H])(OC1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C2C([H])=C([H])C(=NC2=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])OC3=C4C([H])=C([H])C(=NC4=C([H])C([H])=C3OC2([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])N(C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(SC3=NN4C([H])=C([H])C([H])=C4C(=N3)N([H])C3=NN([H])C(=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])[C@]([H])(OC2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])=C(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(C1=C([H])C(N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=NC([H])=C2Cl)C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C(=O)C1=NC([H])=C([H])S1
[H]OC(=O)[C@@]1([H])O[C@]2(O[C@](C(=O)O[H])([C@]([H])(O[H])[C@@]2([H])O[H])[C@]1(O[H])C(=O)O[H])C([H])([H])C([H])([H])C(=C([H])[H])[C@@]([H])(C(=O)C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C2C(N([H])C([H])=C2S(=O)(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C(=C(C#N)C#N)C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C(Cl)C([H])=C2N=NN(C2=N1)C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N2C(=O)C([H])([H])N(C(=O)OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])C(=O)C1=NC([H])=C([H])S1
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C([H])C(=C([H])C([H])=C2N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NN2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N([H])C1=O
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C(S1)C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])[C@]([H])(N([H])[C@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C1=O
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C(=O)O[H]
[H]OC1=C2C(=O)OC([H])([H])C2=C(C(OC([H])([H])[H])=C1C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]\C(=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([O-])=O)C([H])([H])C(\[H])=C(\[H])[C@]1([H])C([H])([H])[C@@]1([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3S2)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
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[H]N1C([H])([H])[C@]2([H])N(C3=C(C(Cl)=C([H])C([H])=C3C2([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
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[H]C1=C([H])C(F)=C([H])C(=C1[H])C(=O)N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H]
[H]N1C2=C([H])C([H])=NN2[C@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C2=C([H])C(=NO2)C([H])([H])[H])=C1C([H])([H])OC([H])([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=NC(=N1)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N(C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1N=C([C@]2([H])C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(C([H])=C3[H])C3(C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C(=O)[C@]12[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=NOC(=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C(SC([H])([H])C([H])([H])SC1(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)C1=NN(C(=C1C([H])([H])C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
ClCC1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
[H]N(C(=O)C1=C([H])OC2=C([H])C([H])=C([H])C([H])=C2C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2Cl)C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C1C(F)(F)F)C([H])([H])N(C(=O)C1=C([H])C(=C([H])C([H])=C1C1=C([H])C(F)=C(F)C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C2([H])[H]
[H]N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C([H])=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])C2=C(C(N([H])[H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@](C1=C([H])N([H])C([H])=N1)(C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C2=C3N(C(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C3=C1[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2N2C([H])=NC([H])=C12)N(C([H])([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2[C@@]1([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=C([H])C2=C(C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C(C2=C([H])C(Cl)=C([H])C([H])=C2S1)C([H])([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C2=NOC3=C2C([H])=C([H])C(OC([H])([H])[H])=C3[H])C2=C([H])C([H])=C(C([H])=C12)C(F)(F)F)C([H])([H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C1=NC(=C([H])C([H])=N1)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(C#CC2=C([H])N=C3C([H])=C([H])C([H])=C([H])N23)=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])N=C2C([H])=C([H])C(=NN12)N([H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]1(C2=NC([H])([H])C([H])([H])C([H])([H])N2[H])C([H])([H])[C@@]2([H])N([C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C([H])C([H])=C(C([H])=C3Cl)C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C2C(=NC([H])=NC2=C1[H])N([H])C1=C([H])C(C#C[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(N([H])C2=C([H])C3=C(C([H])=C2Cl)C(=O)N([H])N([H])C3=O)=C1[H]
[H]N1C(=N[C@](C2=C([H])C([H])=C(F)N=C2[H])(C2=C([H])C([H])=C(F)C([H])=C2[H])[C@]1([H])C([H])([H])[H])C1=C([H])N([H])C(=O)C([H])=C1[H]
[H]N1N=C(N=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]O\C(=C(\C#N)C(=O)N([H])C1=C(C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C(F)(F)F)C([H])([H])[H]
[H]N1C(=NO[S@@]1=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=NC(=C([H])C(=C2N=C1C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])[C@@]([H])(OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C([H])C(Cl)=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])O1)C(=O)N1C([H])([H])C([H])([H])OC2(C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C(=O)OC1=C([H])C2=C(C([H])=C1[H])N(C([H])([H])[H])[C@]1([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])[N@@+]1([O-])C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1F
[H]C1=NC(Br)=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C([H])([H])C1=NN(C(=C1C([H])([H])[H])C1=C([H])N=C(C([H])=C1[H])C(F)(F)F)C1=C(Cl)C([H])=C([H])C([H])=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])OC(=O)C1=C([H])C(O[H])=C(C(=O)C2=C(N([H])S(=O)(=O)C(F)(F)F)C([H])=C([H])C([H])=C2O[H])C(O[H])=C1[H]
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[H]OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C(\[H])=C(/[H])C(=O)N([H])C1=C([H])C2=C(N=C([H])N=C2N([H])C2=C([H])C(Br)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]N(C([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C(F)(F)F
[H]N1N=C(SC1=S)C1=NN([H])C(=S)S1
[H]OC1=C(O[H])C(=C([H])C(\C([H])=C(/C#N)C(=O)N([H])[H])=C1[H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C([H])C([H])=C3S2)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])S2)C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
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FC1=CC=C(C=C1F)N1CNC(=O)C11CCN(CCNC(=O)C2=CN=C3C=CC=CC3=C2)CC1
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[H]N([H])C1=NC2=C(N=C([H])N2C([H])([H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])C(=N1)C1=C([H])C([H])=C([H])O1
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[H]N(N([H])C1=C([H])C([H])=C([H])C2=C1N=C([H])C([H])=C2[H])C(=C1/C([H])=C([H])C([H])=C([H])C1=O)\C([H])([H])[H]
[H]N1C(=O)C2=C(C1=O)C1=C(N([H])C3=C1C([H])=C([H])C([H])=C3[H])N1N=C([H])C([H])=C21
[H]OC([H])([H])[C@@]1([H])N(C2=NC(N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C3N=C([H])N(C3=N2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[S@](=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]2(C([H])=C([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N=C(S1)\N=C(/[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C1=C([H])N2C3=C1C([H])=C([H])C([H])=C3C(=O)N([H])C([H])([H])C2([H])[H]
[H]O[C@@]([H])(C([H])([H])[H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N(C(=O)[C@]([H])(N(C1=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]OP(=O)(O[H])C(F)(F)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@](N1N=NC2=C1C([H])=C([H])C([H])=C2[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C2=C(N=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C(C(=O)OC([H])([H])C([H])([H])[H])=C2C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]