[H]N(C(=S)N([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(C2=NC3=C(N2[H])N(C(=O)N(C3=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C1O[H]
[H]N([H])C1=NC2=C(C(SC3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(S2)C([H])([H])C([H])([H])[H])C(=O)N1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C(C([H])=N1)[C@]([H])(C1=C([H])C([H])=C(OC([H])(F)F)C(OC([H])(F)F)=C1[H])C([H])([H])C1=C([H])C([H])=[N+]([O-])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N=C(C([H])=C1[H])N1N=C(C([H])=C1C(F)(F)F)C1=C([H])C([H])=C([H])N=C1[H]
[H]N1C(=NC2=C1C(Br)=C([H])C(Br)=C2[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N1C([H])([H])C2=C(C([H])=C([H])C(OC([H])([H])C3([H])C([H])([H])C([H])([H])N(C4=C(C([H])=NC([H])=C4[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C2[H])C(=O)N(C([H])([H])[H])[C@]11C([H])([H])N(C(=O)N(C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C3=NC4=C(O3)C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]N(C1=C2C([H])=C([H])C([H])=C([H])C2=C(N=N1)C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])[C@]([H])(OC([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1=C([H])C(=C(C#N)C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]OC1=C(Cl)C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OP(=O)(O[H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C(N([H])[H])=C1[H])C(=O)N([H])C1(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C(N=C2C([H])=C([H])C([H])=C([H])C2=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]N(C(=O)C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C1=O)[C@]([H])(C(=O)OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[N+]([H])([H])[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C(Br)N=C1OC([H])([H])[H])S(=O)(=O)C1=C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C([H])C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N2[C@]([H])(C(=O)N([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)N([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C2C(SC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])=C([H])N([H])C2=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NO1)C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])S(=O)(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(OC(=O)C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1=NC([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])[C@@]2([H])C([H])([H])N(C3=C([H])C4=C(C([H])=C3[H])C3=C([H])C([H])=C(C([H])=C3C4=O)N3C([H])([H])[C@@]4([H])N([H])C([H])([H])[C@@]4([H])C3([H])[H])C([H])([H])[C@@]12[H]
[H]N(C(=O)OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1([H])[H])C1=C3C([H])([H])C([H])([H])C2=NN(C([H])=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(Br)=C2C(=C1[H])[C@](OC2([H])[H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(O[H])C([H])([H])N([H])[C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])=C(C(=O)N2C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C([H])C(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)O[C@]1([H])C([H])([H])[C@]2([H])O[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)OC([H])([H])[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N([H])C([H])([H])[C@]1([H])N(C([H])([H])C2=C(F)C(F)=C([H])C([H])=C2F)C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C2=C(OC(=N2)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H]
[H]C1=C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]2([H])C([H])([H])N(C([H])([H])[C@]2([H])C1([H])[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])[C@]([H])(N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])N([H])[C@]1([H])C(=O)N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
Cl.C=CCCN1CCC2(CCCC3=CC=CC=C23)CC1
[H]N(C(=O)C1=C([H])N=C(OC([H])([H])C(F)(F)F)C([H])=C1[H])[C@]1([H])C([H])([H])OC2=C([H])C([H])=C([H])C(C3=C([H])N=C(N=C3[H])C([H])([H])[H])=C2C1([H])[H]
[H]C1=C(Cl)C(=C([H])C(=C1[H])S(=O)(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[N+]([O-])=O
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])\N=C(\N([H])[H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C2([H])N([H])C([H])([H])C([H])([H])N2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=NC(=C([H])C([H])=N2)C2=C([H])C(OC([H])([H])C([H])([H])\C([H])=C([H])\C([H])([H])N(C([H])([H])[H])C([H])([H])C3=C([H])C1=C([H])C([H])=C3OC([H])([H])[H])=C([H])C([H])=C2[H]
[H]OC([H])([H])[C@@]([H])(C(=O)O[C@@]1([H])C([H])([H])[C@@]2([H])[C@]3([H])O[C@]3([H])[C@@]([H])(C1([H])[H])[N+]2(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N([H])C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C1([H])[H]
[H]N1C([H])([H])[C@]2([H])[C@@]([H])(C([H])([H])OC([H])([H])C([H])([H])[H])[C@]2(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=NC(=NS1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])O[C@@]2([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])=C(C2=C([H])N(C3=C2C([H])=C([H])C(F)=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C2=NC([H])=NC(N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2C([H])=N1
[H]N(N1C2=C([H])C([H])=C(Cl)C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
ON(=O)C1=CN=C2NC=C(\C=C3/N=C(NCC4=CC=CC=C4)NC3=O)C2=C1
[H]C1=C(N=C(Cl)C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[C@@]12C(=O)C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(O1)C(=O)N(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]N(C(=O)C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C1=C(SC([H])=C1[H])C1=NN=C([H])O1
[H]N1C(=C(C(=O)OC([H])([H])[H])[C@@]([H])(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C2=O)S(=O)(=O)C([H])([H])C1([H])[H]
[H]N1C(=C(C#N)[C@@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=N2)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(C2=C([H])C([H])=C(C([H])=C12)N1C([H])=C([H])C(=C([H])C1=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CN(C)CCOC1=CC=C(NC(=O)NC2=CC=C(C=C2)C2=NC(=NC(=N2)N2CCOCC2)N2C3CCC2COC3)C=C1
[H]C1=C(SC2=C1N=C([H])N(C2=O)[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@]2([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]([H])(C1=C([H])SC(=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C(F)=C3[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C2C([H])=NN(C2=NC(SC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=N1)C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1(C([H])([H])N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)N2C([H])=NN=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(O[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(OC([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1C([H])=C([H])C2=C([H])C([H])=C3C([H])=NC([H])=C([H])C3=C12
[H]N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C3[H])C([H])([H])[C@]12[H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]N1[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(C(=O)OC([H])([H])C([H])([H])F)[C@]([H])(C1=C([H])C([H])=C(I)C([H])=C1[H])C2([H])[H]
[H]C1=C([H])C([H])=C(C#CC([H])([H])O\N=C2/C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C3([H])[H])C([H])=C1[H]
[H]C1=C(SC(SC2=C([H])C([H])=C(C([H])=C2[H])N(C(=O)C([H])([H])[H])C([H])([H])[H])=N1)[C@@]1(OC(OC1([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]OC1=C(F)C([H])=C(C([H])=C1F)C([H])([H])N1C([H])=NC2=C([H])C([H])=C(C#CC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C1=O
[H]N([C@]1([H])C(=O)N(C([H])([H])C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C2=C(N1[H])C([H])=C(Cl)C([H])=C2[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)N([H])C1=NC([H])([H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(N([H])C1=C(Br)C([H])=NC(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])[S@](=O)(=NC(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C([H])C2=C1SC(=N2)C1=C([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C([H])=C([H])C(=C([H])C2=NN1[H])C1=NC(=NC(=C1[H])N1C([H])([H])[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C1([H])[H])N([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C([H])=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C(=C([H])C([H])=C3[H])[N+]([O-])=O)C2=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N([H])C1=C(OC([H])([H])[H])N=C(C([H])=N1)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)O\N=C1/C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(N([H])C3=NC(=C([H])C([H])=N3)C3=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N(C(=O)N(C1=O)C([H])([H])[C@]([H])(N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1F)C(F)(F)F
[H]OC1=C([H])C2=C(C([H])=C1Cl)N(C1=C(C(=O)ON1[H])C2=O)C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C([H])=C(OC(F)(F)F)C([H])=C2[H]
[H]N1C([H])([H])C([H])([H])C([H])(N2C([H])=NC(=C2C2=C([H])C([H])=NC(OC3=C([H])C(F)=C([H])C(F)=C3[H])=N2)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])C([H])([H])S[C@@]1([H])OC2=C(C([H])=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])C(=O)[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(O[C@@]2(N(C(=O)C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C(OC2=C([H])C([H])=C(F)C([H])=C2[H])=NC([H])=C1C(F)(F)F
CC(C)C[C@H]1CN(C[C@H](C)N1)C1=CC=C(F)C(=N1)C1=NNC2=C1C=CC=N2
[H]OC(=O)C1=C(OC2=NC(OC3=C([H])C([H])=C([H])C(=C3[H])C(=N[H])N([H])[H])=C(F)C(N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2F)C([H])=C([H])C(=C1[H])C(=O)N([H])[C@@]([H])(C([H])([H])O[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@@]1(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N(C(=O)[C@]([H])(N([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])[N+]([H])([H])[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]([H])(O[H])C([H])([H])N2N=C(C3=C2C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C3([H])[H])C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])[H])C1=C(C(=NC2=C([H])C(Cl)=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1N([H])C1=C(N([H])C2=C(Br)C([H])=C([H])C([H])=C2[H])C(=O)C1=O)[N+]([O-])=O
[H]N(C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)C1=C([H])C([H])=C(O1)C([H])([H])N([H])C([H])([H])C([H])([H])S(=O)(=O)C1=NC([H])=C([H])N1C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C(=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])C([H])([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(C#N)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N1C([H])=NC2=C1N=C(N1N=C(N=C21)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)O[H]
[H]C1=NN(C([H])=C1C1=NC(C2=C([H])C([H])=C([H])C([H])=C2Cl)=C(C([H])=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]OP(=O)(O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]1([H])N(C(=O)N2C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=O)[C@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(\C(=N/C#N)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C(Cl)C(=C2Cl)C([H])([H])OC2=C3N=C(C([H])=NC3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])N(C([H])=N1)[C@]1([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C1([H])[H]
[H]OC1=C([H])C(F)=C(C([H])=C1F)C1=C([H])C([H])=C2C(Cl)=C(O[H])C([H])=C([H])C2=C1[H]
[H]N(C(=O)N([H])C1=C(Cl)C([H])=C(OC2=C([H])C([H])=NC(=C2[H])C2=NC([H])=C(N2[H])C(F)(F)F)C([H])=C1[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
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[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]OC1=C(O[H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C2=C3C(=NC4=C2C([H])=C([H])C(Cl)=C4[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H]
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[H]C1=C(OC2=C([H])C([H])=C(OC(=O)C([H])([H])[H])C([H])=C12)C(=O)C1=C([H])C2=C(O1)C([H])=C([H])C(OC(=O)C([H])([H])[H])=C2[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C([H])C(=C(C(=N1)C([H])([H])[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC([H])=C1C([H])([H])[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N1C(=O)ON=C1C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(C([H])=C(S2)C([H])([H])C([H])([H])[H])C(=O)N(C1=O)C([H])([H])C(=O)C1=C([H])C([H])=C(Cl)S1
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[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C([H])([H])C(=O)OC([H])([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H]
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[H]N([C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])C(C(=O)N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)[C@@]2([H])C([H])([H])C([H])=C([H])C([H])([H])[C@@]2([H])C1=O)C1=NC([H])=C([H])S1
[H]C1=C([H])C(=C([H])C([H])=C1F)C1=C(N=C(S1)C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C2=C([H])C(OC(F)(F)F)=C([H])C([H])=C2[H])C([H])([H])[C@@]11C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NN([H])N=N1
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)O[H]
[H]OC1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C(=O)N([H])C1=C([H])C(Cl)=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(N([H])C(=O)N([H])C2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C2C([H])=C(C(=O)N(N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C2=N1)C1=C([H])C(F)=C(OC([H])([H])[H])N=C1[H])C([H])([H])[H]
[H]N1C(=O)C2=C3C4=C(C([H])=C([H])C([H])=C4[H])N4C3=C3N(C5=C(C([H])=C([H])C([H])=C5[H])C3=C2C1([H])[H])[C@@]1(O[C@@]4([H])C([H])([H])[C@]([H])(N(C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])[C@]1([H])OC([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C(=O)C1=C(N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])OC(=O)C1=C([H])C(O[H])=C(C(=O)C2=C(C([H])=C([H])C([H])=C2O[H])C(=O)OC([H])([H])[H])C(O[H])=C1[H]
[H]C1=NC2=C(C([H])=C1[H])N1C(=NC(=C1C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])N2C1=C(Cl)C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C(OC(F)(F)F)C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])OC1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NC(=NN(C1=O)[C@]([H])(C([H])([H])OC([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C(=C(OC([H])(F)F)N=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(N(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C([H])([H])[C@]2([H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N1N=C(C2=C(ON=C2C1=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
[H]N1C2=NN(C([H])=C2C(=NC2=C1C([H])=C([H])C(I)=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C(OC(F)(F)F)C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C(\[H])=C(\[H])[C@@]([H])(C#CC2=C([H])C([H])=C([H])C([H])=N2)C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]N1C(=O)C2=C(C3=C(N(C4=C([H])C([H])=C(C([H])=C34)C(=O)C3=C(C([H])=C([H])S3)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C3=C2C2=C([H])N(N=C2C([H])([H])C3([H])[H])C([H])([H])[H])C1([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(=C2[H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(OC([H])([H])[H])C(C2=NC(OC([H])([H])C([H])([H])C([H])([H])[H])=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=N2)C([H])([H])[H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(OC2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC1([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)C2(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)N([H])[C@]2([H])C([H])([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])[C@@]2([H])C([H])([H])C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H]
[H]SC1=NC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C(C([H])=C(F)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@]2(O[H])C(=O)C([H])([H])SC2=NC3=C(S2)C([H])=C([H])C([H])=N3)[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C(=O)C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]12[H]
CCN(CC)C1=CC=C(CN(CC2=CC=CC=C2)S(=O)(=O)C2=CC=C(C)C=C2)C=C1
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C([H])=C(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1Cl)C([H])([H])C1=C(C([H])=C([H])C([H])=C1F)C(F)(F)F
[H]ON1C2=C(C(=NN2C([H])([H])[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])C(=O)C2=C([H])C(Cl)=C([H])C([H])=C12
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]C1=C([H])C(=C([H])C(=C1[H])N1N=C(C#N)C(=O)N(C1=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
C=CC(=O)NC1=CC=C(C=C1)S(=O)(=O)N1CCNCC1
[H]N(C1=C([H])C([H])=C(F)C(Cl)=C1[H])C1=C2C([H])=C(N([H])C([H])([H])C3=C([H])N(N=N3)C([H])([H])C3=C([H])N=C([H])C([H])=C3[H])C([H])=C(Br)C2=NC([H])=C1C#N
[H]OC1=C([H])\C(=N\C2=C3C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C3=NC([H])=N2)C(=O)C(OC([H])([H])[H])=C1Cl
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C2=C1N([H])C1=C([H])C([H])=C(C([H])=C21)C([H])([H])[H]
[H]N(C1=NC(=NC2=C([H])C([H])=C(Cl)C([H])=C12)N1C([H])([H])C([H])([H])C2(C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC1=C([H])C([H])=C([H])N(C1=O)C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])C#N
[H]OC1=NC(\C([H])=C(/[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C(C2=C([H])C([H])=C3N=C(N([H])C4=C(Cl)C([H])=C([H])C([H])=C4Cl)N(C3=C12)C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(N=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C2(C(=O)N(C3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])N=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
COCC1=CC(OC)=C(C(OC)=C1)C1=CC=CC2=C(N(CC3CC3)CC3CCOCC3)C(OC)=NN12
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C2C([H])=C([H])C([H])=C(C2=C([H])C([H])=C1[H])S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1C(=O)N([H])[C@@]([H])(C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N1C(=O)N([H])C(N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])C2([H])[H])=C(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(OC(=O)C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]\C(=C(/N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O\N=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)[C@@]([H])(OC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C(=O)O[H]
[H]C1=C([H])N(C(=O)C2=C3N=C(C([H])=C(N3N=C2[H])C([H])(F)F)C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1SC([H])=C2[H])C1=C(F)C([H])=C(C([H])=C1[H])C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)N(C1=NC(=NC([H])=C1[H])N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]C1=C([H])C([H])([H])N(C(=O)N2OC(=O)C(=C2C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(OC(=O)C3=C2OC(=C([H])[C@@]3([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])C(=O)N([H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC(=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C([H])S1
[H]N(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C(S1)C([H])([H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]([H])(OC(=O)[C@@]3([H])C([H])([H])[H])[C@@]1([H])[C@]2([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C1=C([H])C(=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1F)C([H])([H])N([H])C(=O)C1=C(F)C([H])=C(C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N2C([H])([H])SC([H])([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@]2(C([H])=C([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])C2=C([H])N=NC([H])=C2[H])C([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C2=C(Cl)C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(C2=C([H])C3=C([H])N=C(N=C3C([H])=C2[H])N([H])C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)C1=C([H])C([H])=C(N([H])C2=NC(=NC(=C2C([H])([H])C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C([H])C(=C([H])N2C([H])=C1C1=C([H])C([H])=C([H])C(Cl)=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C(Cl)=C(OC([H])([H])[H])C(Cl)=C1[H])C([H])(F)F
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])N(C([H])=N1)C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])N2C(=NC(=C2C2=C([H])C([H])=C(C#N)C([H])=C2[H])[C@]([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C([H])C(OC(F)(F)F)=C2[H])C([H])([H])C2([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C([H])([H])[H])C(=N1)C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(S1)C([H])=C([H])C(OC([H])([H])C1=C(ON=C1C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])(C([H])([H])[H])C([H])([H])[H])=C2[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(SC([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)N3C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])[C@@]3([H])C2=O)C([H])([H])C1([H])[H]
[H]O[C@]([H])(N(C1=NC2=C(N([H])C([H])([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=C(C(=O)C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C(Cl)=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=S)N([H])\N=C(\C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H]
[H]N([H])[C@](C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1F)C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]N(C(=O)C1=NN([H])C([H])=C1[H])[C@@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(OC2=C([H])C(Cl)=C(C#N)C([H])=C2[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C(C([H])=C([H])C([H])=C1OC([H])([H])[H])C(=O)C([H])([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C(=C(C([H])=C1[H])N1C(=O)C2=C(OC([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])N=C3C(OC([H])([H])C([H])([H])[H])=C2C1([H])[H])C([H])([H])[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])N(C(=O)C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])[H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])[H])=C(OC([H])([H])C([H])([H])[H])C([H])=C12)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C2=C(S1)S(=O)(=O)N(C([H])=C2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)N(C(=O)OC1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H])C1=C([H])C(F)=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C(C2=C(O1)C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])[C@@]1([H])[C@@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C1=NC2=C(S1)N=C(N=C2N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)N(C([H])([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N([H])C1=NC2=C(O[C@@]3([H])C([H])([H])N(C([H])([H])C3([H])[H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N([H])[C@]1([H])C([H])([H])N(C2=C(C#N)C3=C(N2C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])C2=NC([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])O[H]