[H]OC([H])([H])[C@]([H])(N([H])C1=NC(SC([H])([H])C2=C(F)C(Cl)=C([H])C([H])=C2[H])=NC2=C1SC(=N2)N([H])[H])C([H])([H])[H]
[H]N1C(=S)N(C2=C(C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N3C4=C(C(OC([H])([H])[H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C3=O)C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])C([H])([H])C([H])([H])F)[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])SC1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]N=C(N([H])C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]C1=C([H])C([H])=C2C(SC(=C2[C@@]([H])(C2=C([H])C([H])=C(N=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N([H])C(=NC(=O)C1=C(N([H])[H])C([H])=C(O1)C1=C(F)C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]C1=NC2=C(C([H])=C1C(F)(F)F)C([H])([H])N(C(=O)C1=C([H])C(=C([H])C([H])=C1O[C@@]([H])(C([H])([H])[H])C(F)(F)F)S(=O)(=O)C([H])([H])[H])C2([H])[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])N2N=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2C(=O)N(C(=O)N([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C(O1)C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)[C@@]([H])(S[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C1=C23
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])=C4[C@]5([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@]5(C(=O)OC([H])([H])C5=C([H])C([H])=C([H])C([H])=C5[H])C([H])([H])C([H])([H])[C@@]4(C([H])([H])[H])[C@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C3=NOC(=N3)C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(F)=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])[C@]([H])(N([H])[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])S1
[H]OC(=O)C1=C(ON=C1C([H])([H])SC1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C(\[H])=N\O[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])C2=NC3=C(O2)C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(C1=C([H])C([H])=C([H])S1)C([H])([H])C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])N([H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C2=C(OC([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C([H])C(=C23)C1([H])[H]
[H]N([H])C(=O)C1=C(N=C(N=C1[H])N([H])[C@]1([H])C([H])([H])C([H])([H])OC([H])([H])[C@]1([H])N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(C2=NN=C(N2C([H])([H])[H])[C@@]23C([H])([H])C([H])([H])[C@@](C([H])([H])C([H])([H])S(=O)(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])C2([H])[H])C([H])([H])C3([H])[H])=C(C([H])=C1[H])C(F)(F)F
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2C([H])([H])[H]
[H]N1C2=C([H])C(=O)C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(C(=O)C4=C([H])C([H])=C([H])C5=C4C([H])=C([H])C([H])=C5[H])C([H])([H])C([H])([H])[C@]3([H])[C@]2([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])N=C2N(C(=O)C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C([H])C(Cl)=C2[H])C1=O
[H]OC(=O)[C@@]([H])(N([H])C1=C(C([H])=NC([H])=N1)C1=C([H])C([H])=C([H])S1)C([H])([H])C1=C([H])C([H])=C(OC(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(ON=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])N([H])[C@]([H])(C([H])([H])SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]C1=C2C(=O)N(C(=O)C2=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(C2=NSN=C2SC([H])([H])C([H])([H])C([H])([H])SC2=NSN=C2C2=C([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C2N=C(N(C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C(F)C(F)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C2N(C3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C([H])([H])C(=O)N(C2=C1[H])C([H])([H])[H])C1=C([H])C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC2=C(N=NN2C2=C1C([H])=C([H])C([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)OC([H])([H])[C@@]1([H])O[C@@]([H])(OC(=O)C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C2=C(C([H])=C1[H])C1=C(N2[H])C2=C(C3=C4N2C([H])([H])C([H])([H])C([H])([H])C4=C([H])C([H])=C3[H])C2=C1C(=O)N([H])C2=O
[H]C1=C([H])C(=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(I)=C1OC([H])([H])[H])[C@@]1([H])C([H])([H])C2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
FC1=C(C=C(CC2=NNC(=O)C3=C2C=CC=C3)C=C1)C(=O)N1CCCC1C(=O)N1CCC2=C3C1CNC(=O)C3=CC=C2
[H]N1C([H])([H])C([H])([H])C([H])(N2C([H])=NC(=C2C2=C([H])C([H])=NC(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])=N2)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C(Cl)=C([H])C(F)=C1[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=C([H])N([C@@]([H])(C1=O)C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(Cl)C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])[C@@]([H])(N(C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=NN2C(=N1)C(O[H])=NC1=C([H])C(=C(N([H])[H])C([H])=C21)[N+]([O-])=O
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])S[H])C(=O)O[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=C(C([H])=C2C#N)C(=O)OC([H])([H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]O[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@]([H])(N([H])C(=O)C(C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1Br)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(O[H])C(Cl)=C2C(=C1Cl)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1O2)C([H])([H])[H]
[H]N=C(N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C(C([H])=C(OC([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C1[H])C(=O)N([H])C1=NC([H])=C(Cl)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])C2([H])[H])C([H])([H])N([H])[C@]1([H])C(=O)N1C([H])([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]1(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C2[H])C([H])([H])N(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NO[C@@](C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])(C([H])([H])N2N=NN=C2[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(N3C([H])=NC4=C(SC(=C4[H])C4=C([H])C([H])=C(Cl)C([H])=C4[H])C3=O)C2([H])[H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])SC1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N1C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])S[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(O[H])C(=O)O[H]
[H]N(C1=NN=C(C2=C1C([H])=NN2C1=C(F)C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C(F)=C1C([H])([H])[H])C(=O)N([H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(O[H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)C1=NC([H])=C(O1)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C(=O)O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@]([H])(O[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]\C(=C(\[H])C1=C([H])C([H])=NC([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[N+]([O-])=O)C([H])([H])[H]
[H]OP(=O)(O[H])C([H])([H])N([H])[C@]([H])(C1=NN([H])N=N1)C([H])([H])C1=C([H])C([H])=C2C(=C1[H])N(C1=C2C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]N(C(=O)C([H])([H])N1C([H])=NC2=C(N=NN2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(\N=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@@]1([H])C2=C(N([H])C([H])=NC1([H])[H])N(C([H])=N2)C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]C1=NC(=C([H])C([H])=C1[H])C1=NC(=C(SC2=C([H])C([H])=C(Cl)C([H])=C2[H])N1C([H])([H])[H])C1=C([H])N=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]N(C1=NC(C#N)=C([H])N(C1=O)[C@]([H])(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C(=C(OC([H])([H])[H])N=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(OC([H])([H])[C@@]2([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@]3([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C2=C(N=C(N=C2C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(N=N1)C([H])([H])C([H])([H])C#N)C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(SC([H])([H])C2=NC(=C(O2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(Cl)=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]O[C@]1(C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])[C@@]2([H])N(C([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C([H])C([H])=C([H])C([H])=C3Cl)[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC([H])([H])C([H])([H])N1N=NN=C1[C@]([H])(N([H])C(=O)C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C1=NN(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NN2C(=C([H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=NC([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])N=C([H])C([H])=C1[H])[C@@]1([H])C([H])=C(C#CC2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(\C(=N/C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])OC([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=NC2=C(C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])N1C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NN=NN1[H]
[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(C2=NC(=C3N2C([H])=C([H])N=C3N([H])[H])C2=C(F)C([H])=C(C([H])=C2[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)N(C([H])([H])C1=C([H])C(C#CC2([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(C#CC2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N([H])C1=NC2=C(N=NN2C([H])([H])C2=C([H])C([H])=C(N([H])[H])C(=C2[H])C([H])([H])[H])C(=N1)C1=C([H])C([H])=C([H])O1
[H]O[C@]1(OC([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2C([H])=C(C#CC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])N([H])[H])C([H])=C([H])C2=C1[H]
CC1CCC(CC1)=NNC1=NC(=CS1)C1=C(Cl)C=C(Cl)C=C1
[H]O[C@@]12C([H])([H])C([H])([H])C(=O)C([H])([H])[C@]11C3=C(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]2([H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])=C(N=C1C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(Br)N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C1=C([H])N=C2C([H])=C(Cl)C([H])=C([H])C2=C1N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C(N([H])S(=O)(=O)C(F)(F)F)C([H])=C([H])N=C1[H]
[H]N(C1=C(C(OC([H])([H])C([H])([H])OC2=NC([H])=C(SC([H])([H])[H])C([H])=N2)=NC([H])=N1)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N(C([H])([H])C2=C([H])C(N([H])C3=C([H])C([H])=C4OC([H])([H])OC4=C3[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N([H])C2=NC([H])([H])C([H])([H])C([H])([H])N2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C(C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC1=C(C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(N([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2N=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
C[C@@H](N1CCCCC1)C1=CC(OC(=O)N(C)C)=CC=C1
[H]OC(=O)[C@]([H])(SC1=NC(N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])=C([H])C(Cl)=N1)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(OC2=C([H])C3=C(C([H])=C([H])N=C3[H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C(=O)N([H])C(=C(C(=O)OC([H])([H])[H])[C@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(OC(=O)C([H])([H])[H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C(=O)N([C@@]1([H])C(=O)N(C2=C(F)C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C(Cl)C([H])=C([H])C2=C1[H])C([H])([H])[H]
[H]OP(=O)(O[H])C1=C([H])C([H])=C(C([H])=C1P(=O)(O[H])O[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])[C@]1([H])C2=C(C([H])=C(OC([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(=C2[H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]\C(=N/C([H])([H])[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C(Br)=C(OC([H])([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=NOC(=N1)C1=NN([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C1=NC2=C(N1[H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])[H]
[H]N(C1=NC([H])=NN1C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C(C(=O)N([H])C1=O)C1=C([H])N(C2=C1C([H])=C(F)C([H])=C2[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(N=C([H])N2C([H])([H])C2=NC([H])=C(C(C#N)=C2C([H])([H])[H])C([H])([H])[H])C(Cl)=N1
CN1C(\C=C\C2=CC=C(C=C2)C#N)=CC2=C1C(=O)N(C)C(=O)N2C
[H]C1=C([H])C([H])=C(S1)C([H])([H])N(C(=O)O[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N(C(=O)N([H])C2=C([H])C([H])=C(F)C(=C2[H])C(F)(F)F)[C@]2([H])C([H])([H])C([H])([H])[C@]3(C4=C([H])N=C(S4)C([H])([H])N([H])[H])C([H])([H])[C@]23[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H])C([H])([H])C1(N2C([H])([H])C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=O)N([H])C(=O)N([H])C1=O
[H]C1=NC2=C(SC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)N=C([H])N=C2N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1F
[H]N1C(=O)N([H])[C@]([H])(C2=C([H])C([H])=C([H])O2)C(C(=O)OC([H])([H])C([H])([H])[H])=C1C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=NN([H])C2=C([H])C(Cl)=C(Br)C([H])=C12
[H]N(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=NC2=C(C([H])=C([H])C(=C2[H])S(=O)(=O)N([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C(=C([H])C(\C([H])=C2/SC(=NC2=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=NN1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])[C@]([H])(O[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])=C1[H]
[H]O[C@@](C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC(N([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C(F)(F)C1([H])[H]
[H]N(C(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C12)S(=O)(=O)C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]N([H])C(=O)O[C@@]1([H])\C(=C([H])\[C@@]([H])(C(=O)[C@@]([H])(OC([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C2=C(N([H])C([H])([H])C([H])=C([H])[H])C(=O)C([H])=C(N([H])C(=O)\C(=C(/[H])\C(\[H])=C([H])/[C@]1([H])OC([H])([H])[H])C([H])([H])[H])C2=O)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C2C(N=C(C(OC3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3C3=NN([H])N=N3)=C2C(=O)O[H])C2([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C2O[C@@]3([H])[C@@]([H])(N([H])C(=O)C4=C([H])C([H])=C(C([H])=C4[H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C2=NC(=NC([H])=C12)N1C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])[C@]1([H])C2=C(OC([H])([H])C1([H])[H])C([H])=C([H])C([H])=C2[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(=C1C([H])([H])[H])C([H])([H])N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]C1=NC(Cl)=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(SC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C(SC(=N1)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])[N+]([O-])=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C2=C(N([H])C(=N2)C2=C([H])C([H])=C(Cl)S2)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C(=O)N2C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])N3C([H])=C([H])C([H])=C3C2([H])[H])C(Cl)=C1[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(N([H])C([H])([H])[H])C(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C1=NN=C2C([H])=C([H])C(=NN12)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]N([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C(OC([H])([H])C([H])([H])[H])=C2[H])C2=NC3=C(C(=NS3)C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(=O)N2[H])C([H])([H])C1([H])[H]
[H]N(\N=C(/C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(C(=O)N([H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(OC1=C(C([H])=C(C([H])=C1[H])[N+]([O-])=O)[N+]([O-])=O)C(=O)C1=C([H])C([H])=C([H])S1
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1OC1=C([H])C(Cl)=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C(F)C([H])=C1[H])[C@@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])[C@]([H])(N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C([H])([H])C1=C([H])C(Br)=C(Br)S1)[C@@]1([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])N(C(=O)C2=C([H])C([H])=C([H])O2)C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C1=C([H])C([H])=C(N=C1[N+]([O-])=O)S(=O)(=O)C([H])([H])[H]
[H]O\C(=C(\SC1=C([H])C([H])=C([H])C([H])=C1[H])/C(/[H])=C(/[H])C(=O)C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C(Cl)C([H])=C([H])C(Cl)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])F
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C(OC1=C([H])C(F)=C([H])C([H])=C1[H])=C2[H])C([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C(=N1)N1C([H])([H])C([H])([H])O[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=NC2=C(N=C(C(=O)N2C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]O[C@@]([H])(C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])C([H])=C([H])C([H])([H])C1([H])[H])C([H])([H])[N+]1=C(N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[N+]([O-])=O)S(=O)(=O)N([H])C1=NC([H])=NC2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1N=C(OC1=S)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C2=C(OC(=O)C3=C([H])C([H])=C([H])C([H])=C3Cl)C([H])=C([H])C([H])=C12
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])N([H])C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C2N=C3C(C([H])=C([H])C([H])=C3C(=O)OC([H])([H])[H])=C2C([H])=C(N1C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C([H])([H])C([H])([H])N1C([H])([H])C(=O)N(C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])C2=C([H])C3=C([H])C([H])=C(N=C3C([H])=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N(C(=O)N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(OC(=O)C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])C1=NN(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N1C(=O)C(=C([H])C2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C12)[C@@]([H])(N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H])C1=NN=NN1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C2C([H])=C([H])C([H])=C([H])C2=NC(=C1[H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)O[C@@]2([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])[C@]12[H]
[H]N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=C([H])C(=NN2[H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]2([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])SSC2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])S2)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N([H])[H]
[H]N([H])C(C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])=[C@]=C([H])C1=C([H])C(O[H])=C2C(OC(C([H])([H])[H])(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])=C1[H]
[H]C1=C([H])[N+](=C([H])S1)C([H])([H])C1=C([H])C([H])=C([H])C(OP([O-])(=O)OC([H])([H])[C@]([H])(OC([H])([H])[H])C([H])([H])OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1(F)[C@]2([H])C([H])([H])[C@@]([H])(OC([H])([H])C3=C(F)C(F)=C(F)C(F)=C3F)[C@@](N([H])[H])(C(=O)O[H])[C@]12[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C(=O)N2[C@@]([H])(SC([H])([H])[C@@]2([H])C#N)C1([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H])C([H])([H])N([H])[H]
O=C(N1CCN(CC2=CC=C(C=C2)C2=NN=C3N2C2=CC=CN=C2NC2=C3C=CC=C2)CC1)C1=CC=CC=C1
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])N(C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])F)C([H])([H])C2([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])SC([H])([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])N([H])[H]
[H]N(C(=O)C1=C(ON=C1C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])[C@]1([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C2=O
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C2=NC(N([H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)=C3N=C(N=C3N2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C#CC2=C([H])N(C(=O)C([H])=C2[H])C([H])(F)F)C([H])=C1[H]
[H]N1C([H])([H])C2=C(C3=C([H])C([H])=C(C([H])=C3O2)S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)N([H])C(=O)C(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])(C1=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C3N2C([H])([H])C([H])([H])C([H])([H])N([H])C3=O)C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H]
[H]C1=NC([H])=C(C2=NC(=C3N2C2=C([H])C(=C([H])C([H])=C2N=C3C([H])([H])[H])C(F)(F)F)C([H])([H])[H])C(=C1[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C(F)C(Cl)=C2[H])C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]N1C(=O)N([H])[C@](C1=O)(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=NN(C([H])=C2C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C(=O)C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])C1([H])[H]
[H]C1=C(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C2([H])[H])C2=C([H])C([H])=C([H])C3=C2N1[C@@]([H])(C([H])([H])O3)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])[C@](C(=O)N([H])[C@@]1(C(=O)OC([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C2=C(N([H])C(=N2)C([H])([H])C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C2C([H])=C([H])C(=C([H])C2=NN1[H])C(=N[H])N([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(OC2=C(F)C(=C(F)C(OC3=C([H])C([H])=C([H])C(N([H])[H])=C3[H])=N2)C([H])([H])[H])=C1[H]
[H]S\C(=N/N=C(/C1=C([H])C([H])=C(Br)S1)C([H])([H])[H])N([H])[H]
[H]N(C(=O)C1=C(N=C(Cl)C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])(N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])SC([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
CS(=O)(=O)C1=CC=C(C(=O)N2CCOC3=CC=C(C=C3C2)C2=CC=C3N=CNC3=C2)C(Cl)=C1
[H]N([H])[C@]([H])(C1=C(N=C(O1)C1=C2C([H])=C([H])C(=NC2=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])SC([H])([H])C1=C(OC(=N1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C([H])=C([H])C(=C([H])C2=NC([H])=N1)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C2=NC3=C(N2[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C1=NC2=C(N=C(N=C2C(=N1)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])C([H])([H])C([H])([H])O[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(N(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])=C2C(SC3=C2N=C([H])N(C3=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])=N1
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC(Cl)=C1C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
S=C(NC1=NN=CS1)NC1=CC=CC=C1
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C2N(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C13)C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])C([H])([H])C([H])([H])N2[H])=C([H])C(O[H])=C1[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1O[H]
[H]N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C1=C(Cl)C([H])=C(Cl)C(OC([H])([H])[H])=C1[H])C1=C2C([H])=C(OC([H])([H])[H])C(C#CC3=C([H])C([H])=C([H])C(=N3)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C2=NC([H])=C1C#N
[H]N(C1=NC(=C([H])C(OC([H])([H])C(F)(F)F)=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(OC([H])([H])[H])=C(N=C1[H])[C@@]([H])(C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]OC12C(=O)C(=C([H])C1([H])C13OC4(OC([H])(C1([H])C([H])=C(C([H])([H])OC(=O)C([H])([H])C1=C([H])C(F)=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C2([H])[H])C(O4)(C(=C([H])[H])C([H])([H])[H])C([H])([H])C3([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C([H])C(=NC2=C1[H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])=NC(=C1[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N([H])C1=C([H])C([H])=C2C(=C1[H])N(C([H])=C2C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]11C(=O)N(C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C#C[H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)[C@@]2([H])N([H])C(=O)N([H])C(=O)C2([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])C3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])N(C(=O)C1=C([H])C(O[H])=C(O[H])C([H])=C21)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C2C([H])=C3C(=NC2=C1[H])C([H])([H])C([H])([H])C3([H])[H])C(=O)[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])OC([H])([H])[C@](N([H])[H])(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(=C(S1)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N([H])C1=C([H])C([H])=C(OC3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])=C1[H])C2([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C([H])([H])[H])C1=C([H])C2=C([H])N=C([H])C([H])=C2N1[H]
[H]N(C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1
[H]N1C([H])=NC(=C1[H])C([H])([H])N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C3=C2C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C12)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]C1=C(N=C(N=C1C1=C(N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])N(C1=C(C([H])=C(C([H])=C1Br)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
C[C@H]1C[C@H](CNS(=O)(=O)C(F)(F)F)CCN1S(=O)(=O)C1=CC2=CC=CC=C2N1S(=O)(=O)C1=C(F)C=CC=C1
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])C(Cl)=C1C(=N2)C([H])([H])C([H])([H])C1([H])[H])C1=C(Cl)N=C([H])C([H])=C1[H]
[H]N1N=NN=C1C1=C([H])C(F)=C([H])C(=C1[H])N(C(=O)C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C(=C(N1[H])C(\[H])=C1/C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]C1=NC2=C([H])C(=C([H])C([H])=C2N1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]O[C@@](C1=C([H])N([H])C([H])=N1)(C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]