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[H]N([H])C(=S)N1N=C(C2=C([H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]OC1=NSC(N([H])C2=C([H])C([H])=C(OC3=C(F)C([H])=C([H])C(=C3[H])C(F)(F)F)C([H])=C2[H])=C1\C(=N\[C@]([H])(C([H])([H])[H])C([H])([H])O[H])N([H])[H]
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[H]N(C(=O)N([H])C([H])([H])[H])C1=NC([H])=C([H])C(OC2=C([H])C([H])=C(N([H])C(=O)N3C(=O)N(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])=C2[H])=C1[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C(F)(F)F)C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)O[C@]1([H])C(=O)N(C(=O)C2=NC3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NN([H])C([H])=C1[H]
[H]C(=O)OC1=C([H])C([H])=C([H])C2=C1C1=C3C(=C([H])C(F)=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]3([H])C2([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C2=C(N([H])C3=C2C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C2N([H])C(=O)C([H])([H])C3=C(N([H])C4=C3C([H])=C(Br)C([H])=C4[H])C2=C([H])C([H])=C1[H]
[H]N(C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(=C([H])S1)C([H])([H])[H]
[H]OC1=C([H])C(=NC2=NC(=C([H])C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C1\C2=C(N([H])C3=C2C([H])=C(Cl)C([H])=C3[H])C(=O)N([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NN2C(=N1)N(C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C(=C([N+]#[C-])C2([H])C1=C(C([H])=C(C#N)C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C(=C(C([H])=C2N=C(C2=C([H])C([H])=C([H])C(=C2[H])C2=C([H])C(=NC([H])=C2[H])N2C([H])=C([H])C([H])=C2[H])C([H])([H])C1=O)C([H])([H])[H])C(F)(F)F
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=NC(=C(O1)C1=C([H])N2C(OC([H])(C([H])([H])[H])C([H])([H])[H])=NN=C2C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C(=C([H])C2=C(C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=NC(=NO1)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C1=C2C([H])=C(C(OC3=C(OC([H])([H])[H])C([H])=C(C([H])=C3OC([H])([H])[H])C([H])([H])OC([H])([H])[H])=NC2=C([H])C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C2=C(N([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OS(=O)(=O)SC([H])([H])C(=N\C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])[C@]1([H])C2(C([H])([H])[H])C([H])([H])[H])\N([H])[H]
[H]N([C@@]([H])(C1=NN(C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
CC1=CC(Cl)=C(OCCOC2=CC=C(C=C2)[C@H]2CCNC[C@@H]2C(=O)N(CC2=CC(CNCCF)=CC=C2Cl)C2CC2)C(Cl)=C1
[H]C1=C(C(C2=C3N=C(N=C(N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C(N=C1N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
COC1=C(O)C=C2OC(=CC(=O)C2=C1O)C1=CC=CC=C1
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1N([H])[H])C1=NN(\C(S1)=N\C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])=C([H])[H]
[H]OP(=O)(O[H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C#CC1=C([H])C([H])=C(F)C([H])=C1F
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1C(=O)N(C2=C(N=C(SC3=C([H])C([H])=C([H])C([H])=C3Br)C([H])=C2[H])C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC(=O)C([H])([H])N([H])C(=O)C([H])([H])[C@]([H])(S[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H]
C(NC1=C2C(NC(=C2C2=CC=CC=C2)C2=CC=CC=C2)=NC=N1)[C@@H]1CCCO1
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H]
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N([C@]([H])(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)N(C(=O)C([H])([H])[C@]12[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C(=NN1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C3=C2OC([H])([H])C([H])([H])O3)C([H])([H])C1([H])[H]
[H]OC1=C2C(=O)OC([H])([H])C2=C(C(OC([H])([H])[H])=C1C([H])([H])C([H])([H])N([H])S(=O)(=O)C([H])([H])S(=O)(=O)N([H])C([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])P(=O)(OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C(Br)=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C3OC([H])([H])C([H])([H])C([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
CN1N=CC2=C1N=C(N=C2NCC(C)(C)CO)C1=CC=CC2=C1C=NN2
[H]N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(OC2=NC([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])C([H])([H])C22C(=O)N([H])C(=O)N([H])C2=O)C([H])=C1[H]
[H]ON([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])SC([H])=N1
[H]N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C([H])C([H])=C2Cl)C1=O
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(OC2=C1C([H])=C([H])C([H])=C2[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C2=NN=C(N2C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C(S1)N(C([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])[C@@]1([H])ON=C(C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C([H])=C(C1=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C(F)=C1[H])C1=C([H])C(F)=C(OC2=C3C([H])=C([H])N([H])C3=NC([H])=C2[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C(=O)C1=C([H])OC([H])=C1[H]
[H]SC([H])([H])[C@]([H])(N([H])[H])C([H])([H])[S@@+]([O-])C([H])([H])[H]
[H]C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C(=NC3=C2C([H])=C([H])C([H])=C3[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=NN([H])C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([C@]1([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=NC4=C(O3)C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])[C@@]([H])(C2=C([H])SC([H])=C2[H])C1([H])[H])C(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C(Cl)=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C2N=C([H])C([H])=C([H])C2=C(C(=C1[H])S(=O)(=O)C1=C(Br)C([H])=C([H])C([H])=C1[H])[N+]([O-])=O
[H]N(C1=NC(=NC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)N1C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C([H])C([H])=C(C([H])=C2N1[H])C([H])([H])[H])C1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C([H])=C1OC2=C([H])C([H])=C(F)C([H])=C2C2=C1C1=C(N([H])C(C([H])=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H]
[H]C1=C(C([H])=C(N1C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N(C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@@]1([H])N(C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C(N([H])C(=O)C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C([H])=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C([H])([H])O[C@@]1([H])C([H])([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(C([H])([H])N([H])C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])C1([H])[H]
[H]N1C(=NC(=C1C1=C([H])C2=C(C([H])=C1[H])N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(\N=C(/[H])C1=C(N(C(=C1[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]C1=NC2=C(C([H])=C(OC3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])C(=O)N1C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C1([H])[H]
[H]N1C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C([H])([H])C([H])([H])OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1N=NC([H])=C1C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12OC([H])([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C(S1)C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1S2(=O)=O)C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1N=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])OC1=C(Cl)C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])N(N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
COC1OC2=C(C3=C(C(O)=C2)[C@@]2(C)C(O3)=CC(O)=C(C(C)=O)C2=O)C(=O)N1C(=O)NCC1=CC=CC=C1N(O)=O
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NO[C@@](C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C(=C2[H])S(=O)(=O)N([H])[H])(C([H])([H])C(=O)OC([H])([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N1C(=O)C(N([H])C([H])([H])C2=NC3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N3[H])=C([H])C([H])=C1C1([H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])N=C(N=C1[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])SC([H])([H])C([H])([H])N([H])C(=N[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])=C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CC[C@@H](C1)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](C(=C)C(N)=O)C1=CC=CC=C1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1(O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)OC2=C1C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(C#N)C2=C([H])C(OC([H])([H])C2=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(O[H])C(O[H])=C(C([H])=C1[H])C1=C([H])C(=O)C2=C(O[H])C([H])=C([H])C(O[H])=C2C1=O
[H]C1=NC([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C3C(OC(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N([H])C1=C(C2=C([H])C3=C(S2)C([H])=C([H])C([H])=C3[H])C(=NC([H])=N1)C#CC1=C([H])N=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(SC(=C2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])OC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1[H]
[H]OC1=NC2=C([H])C(Br)=C([H])C([H])=C2N2N=C(N=C12)C(=O)OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1[H])C1=NN2C(=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2N([H])C1=O)C([H])([H])[H]
[H]OC([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(F)(F)C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2N=C2SC(=C([H])C2=C1N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C1=NN([H])C2=C1C([H])([H])[C@]1([H])[C@@]2([H])[C@]1([H])C([H])([H])C([H])=C([H])[H]
[H]C(=O)C1=C([H])C([H])=C([H])C(=C1[H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=NN2C(=N1)C(=C(N=C2C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1
[H]N(\C([H])=C1/C(=O)N([H])C2=C([H])C(=C([H])C([H])=C12)C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])O[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])[H])C([H])=C1[H]
[H]C1=NC([H])=C(C(=C1[H])C1=NC(=C2N=NC3=C(OC([H])([H])[H])C([H])=C(C([H])=C3N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(C2=NC(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(Br)=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])[C@@]([H])(C2=NC(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2[C@]1([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C(O[C@]([H])(C([H])([H])[H])C([H])([H])O[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1O[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1O[H])C([H])([H])C1=C(O[H])C([H])=C([H])C(O[H])=C1[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[C@]([H])(O[H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NN=NN1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=NC2=C([H])C([H])=C(C#CC([H])([H])N([H])C(=O)C3=C([H])C([H])=C([H])N(C3=O)C([H])([H])C3=C([H])C([H])=C(F)C(F)=C3[H])C([H])=C12
[H]N([H])C1=C2C(SC(=C2C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C(=C([H])C([H])=C3F)C([H])([H])[H])C([H])=C2[H])C([H])([H])[H])=NC([H])=N1
[H]N(C(=O)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]C#CC([H])([H])N(C(=O)C([H])([H])[C@]1([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC([H])([H])C([H])([H])N2C([H])([H])[H])C([H])([H])C([H])([H])N(C1([H])[H])S(=O)(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]OC(=O)C1=C(N([H])N=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C([H])C(Br)=C1[H]
[H]N(C1=NC([H])=NC(N([H])[C@]2([H])C([H])([H])N([H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C2N=C(N=C([H])C2=C1[H])N([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
NS(=O)(=O)C1=CC=C(NC(=O)C(=C\C2=CC3=C(OCO3)C=C2)\C#N)C=C1
[H]OC(=O)[C@]([H])(N(C1=C(C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=S)N([H])C1=C([H])C(F)=C(OC2=C([H])C([H])=NC3=C2SC(=C3[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(C([H])([H])C1=C([H])C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=NC2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)N([H])C1=NN=C(S1)C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N1C(=O)C([H])=C(C2=C1C([H])=C([H])C(=C2[H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(F)(F)F)C(F)(F)F
[H]N([H])C(=O)C1=C(N=C(N=C1[H])C([H])([H])[H])N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC1=C(N([H])C([H])([H])[C@@]2([H])OC([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C2([H])[H])C([H])=C([H])C(Cl)=C1[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])[C@@]12C(=C([H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C2C(N([H])C([H])=C2S(=O)(=O)C2=C(F)C([H])=C(F)C([H])=C2[H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)N([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])N(N=N1)C([H])([H])C([H])([H])OS(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C2=NC(=NC([H])=C12)N1C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])[C@@]1([H])C2=C(OC([H])([H])C1([H])[H])C([H])=C([H])C([H])=C2F
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C3=C(C([H])=C([H])C4=C3C(O[H])=NC(=N4)N([H])[H])C([H])=C2[H])C([H])=C1[H])C(=O)O[H]
[H]O[C@@]([H])(C([H])([H])N1N=C(C2=C1C([H])([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(C(SC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H])C(F)(F)F)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])OC(=O)C1=C(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C2OC([H])([H])OC2=C1[H])[C@]([H])(N1C([H])=NC([H])=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
OC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)CC1=CC=C(NC(=O)NC2=C(C)C=CC=C2C)C=C1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)NCCCCCCCCCCCCN
[H]N(C1=NC(=C([H])C([H])=N1)[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C([H])C(C#CC3=C([H])C([H])=C([H])C([H])=N3)=C([H])C([H])=C12
[H]N(C(=O)C1=C([H])OC2=C([H])C([H])=C([H])C([H])=C2C1=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(I)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=N1)N(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C2=C(OC(F)(F)F)C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C(OC([H])([H])C(F)(F)F)=N1)C1=C([H])C(=C(Cl)C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C(F)=C1F
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN(N=N1)C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C(SC2=C([H])N=C(S2)N([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C(O[H])=C(OC([H])([H])[H])C([H])=C2O1
[H]C1=C([H])C(OC([H])([H])[H])=C(SC2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
CC(C)NC(=O)C1=CC(SC2=CC=C(C=C2)C(C)C)=CN=C1O
[H]O[C@]([H])(C([H])([H])[H])[C@]([H])(OC1=C(Br)C([H])=NC(=N1)N([H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])[S@@](=O)(=N[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC2=C(C([H])=NC3=C2C([H])=C([H])C([H])=C3[H])C(=O)N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C([H])C(F)=C2N=C(N(C(=O)C2=C1[H])C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C([H])=C(Br)C([H])=C2[H]
[H]N([H])C1=NON=C1C1=NC2=C([H])N=C([H])C(C(=O)N([H])C([H])([H])C([H])([H])N([H])C([H])([H])[H])=C2N1C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H]
CCOC[C@@H]1CCCN1S(=O)(=O)C1=CC=C2NC(=O)C(=O)C2=C1
COC1=CC(CNC(=O)N(CCCN(C)C)C2=CC=C(C=C2)C2=CNN=C2)=CC=C1
[H]C1=C([H])C2=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C2N1S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NC([H])=C([H])S1)N([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C1=C2N=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C2C3=C(C([H])=C(N=C3N(C3=C([H])C([H])=C(C#N)C([H])=C3C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H])N1C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)C1=C(OC([H])([H])C(=O)N2C([H])([H])[C@@]([H])(N(C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])[C@@]2([H])C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C(Cl)=C1[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])N(C3=C2C([H])=C(F)C([H])=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C([H])=C(C([H])=C2[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C(Br)C([H])=C2[H])C2=C1C1=C([H])C([H])=C([H])C([H])=C1N(C(=O)C2([H])[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]N1N=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C(C(=O)N([H])C1=O)C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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[H]SC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])S[H]
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[H]C1=C(C([H])=C(SC([H])([H])[H])C(=C1[H])N(C1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])[H]
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[H]ON([H])C(=O)C1=C(N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])N([H])C(=O)C3=C([H])C4=C(O3)C([H])=C([H])C([H])=C4[H])C([H])=C2[H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C(=NC(OC([H])([H])[H])=N1)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NC(OC([H])([H])[H])=C([H])C([H])=C1N1C(=NN=C1C([H])([H])OC([H])([H])C([H])([H])[H])C1=C([H])C(=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@]1([H])[C@@]([H])(N([H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])S(=O)(=O)C([H])([H])[C@@]1([H])C([H])([H])C1=C([H])C(OC([H])(C(F)(F)F)C(F)(F)F)=C(N([H])[H])C(F)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C([H])([H])OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C1/C(=O)[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(SC([H])([H])C([H])([H])N2C(=O)C([H])([H])C([H])([H])[C@]2([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])S1
[H]C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(F)=C1[H])C1=C([H])N=C(C([H])=C1[H])C([H])([H])N(C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C2N=C(Cl)C3=C(C(=O)N(C3=O)C([H])([H])C([H])([H])OC(=O)C([H])([H])[H])C2=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C2=NC([H])=C(C([H])=C2N(C([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(F)=C(F)C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C3N(N=C([H])N=C3N([H])C3=C([H])C(Cl)=C([H])C(Cl)=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
COC1=CC2=NC=CC(OC3=CC=C(NC(=O)NC4=CC=C(F)C=C4F)C(C)=C3)=C2C=C1OC
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C([H])([H])N(C1=C([H])C(Cl)=C(C#N)C([H])=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(N([H])C(=O)[C@@]([H])(N([H])C(=O)C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(Br)C([H])=N2)C([H])=C1[H]
[H]O[P@](=O)(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C2=NC([H])=C(C#N)C(=N2)C2=C([H])C([H])=C3N([H])C([H])=C([H])C3=C2[H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]OC1=C(O[H])C([H])=C(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=C2C([H])=C(N=C([H])C2=NC([H])=N1)N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3C([H])=NC([H])=NC3=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(I)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C(=C1C([H])=[N+](C([H])=C([H])C1=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1(C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC3=C([H])C([H])=C(C([H])=C3[H])C(=O)N([H])C([H])([H])C3=C([H])C([H])=NC([H])=N3)C([H])=C2[H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])[H])C([H])([H])C1(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C2=C1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(F)C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])[C@]12[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(N=C1OC1=C([H])C2=C(C([H])=C([H])N2[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
COC1=CC=C(Cl)C=C1NC(=O)NC1=C2C=CC=CC2=NC(=C1)C(F)(F)F
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])=O)C([H])([H])C#CC([H])([H])[H]
[H]N1N=C([H])C2=C(C([H])=C([H])C([H])=C12)C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(N2C([H])([H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])[C@]2([H])C3([H])[H])C(F)=C1F
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C([H])N=NC(O[H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@@]([H])(N([H])C(=O)C(OC1=C([H])C([H])=C(Cl)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]OC(=O)C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C(=C1C([H])([H])[H])[C@@]1([H])N(C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])S(=O)(=O)C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C(Cl)C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N3C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])C([H])([H])[H])C([H])([H])C3=O)C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]OC1=NC(=NC2=C1C([H])=C(C([H])=C2[H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])C#C[H])C([H])([H])Cl
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=NC(N([H])C([H])([H])[H])=C1[H]
[H]N=C(N([H])[H])N([H])\N=C(/[H])C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(C2=C(OC3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C(F)C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=NOC(=N1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])=C([H])[C@]2([H])C([H])([H])C([H])([H])N(C(=O)[C@]12[H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])C2=NC([H])([H])C([H])([H])N2C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)N1OC(=O)C(=C1C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C(=NC2=C(Br)C([H])=NN12)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC(=O)C1(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])N=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C1=C([H])C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C([H])C(=C(N=C2C(=C1[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])N=C(N1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=NC([H])=C(N=C1[H])C1=C([H])C(F)=C(C([H])=C1[H])C1=NN=C(N1C([H])([H])[H])C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(OC(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])(OC4=C([H])C([H])=C(C([H])=C4[H])S(=O)(=O)C4=C([H])C5=C(OC([H])([H])O5)C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C(Cl)C(=C2Cl)C([H])([H])OC2=C3N=C(C([H])=C(N(C([H])([H])[H])C([H])([H])[H])C3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(OC2=C(N([H])S(=O)(=O)C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C(C([H])=C2[H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]N(C(=O)N([H])C([H])([H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(C#CC2=C([H])C(Br)=C([H])C(C#N)=C2[H])=C([H])C([H])=C1C([H])([H])[H]
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[H]OC1=C(OC([H])([H])C(=O)C([H])([H])C2=C([H])C([H])=C(F)C(=C2[H])[C@]2(N=C(SC([H])([H])C2([H])[H])N([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C2C([H])=C([H])C([H])=NC2=C([H])C([H])=C1[H])C1=C(C(Cl)=C([H])S1)C1=NC([H])=NN1[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=NC(=NC2=C1N=NN2C1=C(Br)C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C2=C(N=C(N2C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C2=NN=NN2[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)O[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])SC2=C([H])C(OC([H])([H])C3=C(N=C(S3)C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])[H])=C(C([H])=C12)C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C([H])=C([H])C(O[C@@]([H])(C(=O)N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])[H])=C12)C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(C([H])([H])C(=O)N1[C@]([H])(C#N)C([H])([H])C([H])([H])[C@]1([H])C#N)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=NC(=N1)C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C2=C(N=C(N(C2=O)C([H])([H])C(=O)N([H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])OC1=NN(C(=C1[H])C1=NC2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NSC([H])=C1N([H])C([H])([H])C1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C([H])=C1C1=C2N=C([H])N([H])C2=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C3=C(N=C(N=C3[H])C#N)N2C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N2C(=O)N(C(=O)[C@]2([H])C1([H])[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])[C@]2([H])C1([H])[H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C(C3=C(S2)C([H])=C([H])C(F)=C3[H])C([H])([H])[H])C(=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2O[C@@]([H])(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])[C@]([H])(C([H])([H])[H])S(=O)(=O)C2=C1[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C(C([H])=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(OC(=C1[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])=NC3=C([H])N=C4N([H])C([H])=C([H])C4=C23)C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])[H])[C@@]([H])(N1C([H])=C([H])C2=C1C([H])=C([H])C(=C2[H])C([H])([H])[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2SC([H])=C(C2=C1[H])[C@]([H])(C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=S)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]O[C@@]([H])(C1=NC([H])=C(O1)C1=NC([H])=C(C([H])=C1[H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C(S1)N1C([H])=NC2=C1C([H])=C(OC1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])=C2[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(OC3=C(C([H])=C([H])C(F)=C3C([H])([H])[H])C([H])([H])[H])N(C3=C([H])C([H])=C([H])N=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])C(=O)C2=C([H])C3=C(C([H])=C([H])C([H])=C3N2C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])N(C(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])[H])=C1[H]
[H]N([H])C(=S)C(\C#N)=C(/[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1C2=C(C(=NN2C([H])([H])[H])C2=C([H])C([H])=C([H])S2)C2=C(C1=O)C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])[H])C1=NC(=C(S1)C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(\C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])[H])=C1/C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])C([H])=C([H])S3)[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N(C1=NC(=C(S1)C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C(F)=C([H])C([H])=C12)C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C2=O)C([H])([H])C1([H])[H]
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[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N1C(SC([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])=NC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(=C(/[H])C1=C(OC2=C([H])C([H])=C([H])N=C2[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2S1)\C1=C([H])C([H])=NC([H])=C1[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C(C(=C1C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N2C3=NC4=C([H])C([H])=C([H])C([H])=C4N3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])C([H])=C2C([H])=C(O[H])C([H])=C([H])C2=C1[H]
[H]N1C2=C([H])C3=NC(SC([H])([H])C(F)(F)F)=C([H])C(=C3C([H])=C2C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C(Cl)C([H])=NC([H])=C1Cl
[H]N=C(N([H])[H])C1=C([H])C([H])=C2C([H])=C(\C([H])=C(/[H])C3=C([H])C4=C(C([H])=C3[H])C([H])([H])N([H])C([H])([H])C4([H])[H])C([H])=C([H])C2=C1[H]
[H]OC1=NC2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])=C1C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(O[H])C(O[H])=C1[H]
[H]N(C1=NC([H])=NC2=C1SC1=C2C([H])=C(N([H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])OC1=C(C([H])=C(Cl)C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C(=N1)N(C([H])=C(C(=O)OC([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(C([H])=C1[H])C(=C([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C(=NN1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(=O)O[H]
[H]N([H])C(=O)N([H])C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\[H])C3=C([H])C(=C([H])N3[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2=C1[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(=C2[H])N1C([H])=NN=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N2C([H])=NN=C12
[H]C1=C([H])C(=C(F)C([H])=C1F)[C@]1([H])C([H])([H])N(C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])[C@]2(O[C@@]([H])(C3=C2C([H])=C(F)C(F)=C3[H])C(C#N)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C(C([H])=C(C([H])=C1[H])[N+]([O-])=O)S(=O)(=O)N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C(=C([H])C2=C([H])C([H])=C([H])C(=C12)C([H])([H])[H])C([H])([H])N(C(=O)[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1[H])C([H])([H])OC1=C(C([H])=C(OC([H])([H])C2=NC3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])=C1[H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])[C@@]3([H])C([H])([H])N(C([H])([H])C([H])([H])F)C([H])([H])C([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C(Br)C([H])=C1F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]O[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1C([H])([H])N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC(=O)C1=C([H])C([H])=C(C(=C1[H])S(=O)(=O)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])N([H])[H]
[H]O[C@@]1([H])[C@@]([H])(S[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C(Cl)N=C12)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(I)=C1[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N2N=NC(=C2[H])[C@@]([H])(N([H])C1=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])[C@@]([H])(C(=O)N1C([H])([H])OC([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])N=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C2=C(N([H])C([H])([H])C#CC3=C4OC(=C([H])C(=O)C4=C([H])C([H])=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(=O)C([H])=C(N([H])C(=O)\C(=C(/[H])\C(\[H])=C([H])/[C@]([H])(OC([H])([H])[H])[C@@]([H])(OC(=O)N([H])[H])\C(=C([H])\[C@]1([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O
[H]OC(=O)N([H])C1=C(C(=O)C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C3=C(N2[H])C(=O)N(C(=O)N3C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C(=O)N1[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC([H])=C(Cl)C(=O)N2C([H])([H])C2=C(C#N)C([H])=C([H])C(F)=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])N=C([H])C([H])=C1[H])[C@@]([H])(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(S2)C2=C([H])C(OC(F)(F)F)=C([H])C([H])=C2[H])C2=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2C(F)(F)F)C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C2=C([H])C(=C([H])C([H])=C12)C1=N[C@@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])O1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])C(F)=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])N1C(=O)[C@@]2([H])[C@@]([H])(C1=O)[C@]1([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1N=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])[C@@]1([H])C([H])([H])[C@]([H])(O[C@@]([H])(O[C@]2([H])[C@@]([H])(C([H])([H])[H])[C@]([H])(O[C@]3([H])O[C@@]([H])(C([H])([H])[H])[C@]([H])(O[H])[C@@](OC([H])([H])[H])(C([H])([H])[H])C3([H])[H])[C@]([H])(C(=O)O[C@]([H])(C([H])([H])C([H])([H])[H])[C@](O[H])(C([H])([H])[H])[C@]([H])(O[H])[C@]([H])(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])[C@]2(OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@]1([H])O[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C([H])C(Br)=C([H])C(OC([H])([H])C3([H])C([H])([H])C([H])([H])N([H])C([H])([H])C3([H])[H])=C2O1
[H]OC1=C2C(=O)C3=C(C([H])=C([H])C(=C3O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C2=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[N+]([O-])=O)C(=O)O[H]
[H]N(C(=O)OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H])C1=C([H])C2=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1([H])SC([H])([H])C([H])([H])S1
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]([H])(N([H])C1=C(N([H])C2=C([H])C([H])=NC([H])=C2[H])C(=O)C1=O)C([H])([H])[H]
[H]OC(=O)C1=C(SC([H])([H])[H])C(=NC2=C([H])C([H])=C(F)C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C(=N1)N1C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])[C@]([H])(C([H])([H])[H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(=N1)N([H])C(SC1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])=C2C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C(=O)C([H])([H])C1=C([H])SC(=N1)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC(=O)C(=N\OC([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H])\C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)S(=O)(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])OC(=O)C([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(\N=N\C2=C(O[H])C([H])=C(C3=C2C([H])=C([H])C([H])=C3[H])S(=O)(=O)O[H])C(=NN1C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=NN1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3C(=O)N(C(=O)C3=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C1=C2N=C(N1C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])[H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]C1=C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]2([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=N3)C([H])([H])[C@]2([H])C1([H])[H]
[H]N(C(=O)OC1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)SC([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C2([H])[H]
[H]N1C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(=C(S1)C1=NOC(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
FC(F)(F)C1=CC=CC=C1C(=O)N1CCN(CC1)C1=NN=C(C=C1)C(=O)NCCCC1=CC=CC=C1
COC1=CC2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=CC=C(C=C3)C(=O)N3CCN(CC3)C3CCCCC3)C2=O)C=C1
[H]N1C(OC([H])([H])[H])=NC2=C(C1=O)C(=C([H])C(=O)O2)C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C2N=C(C(=C([H])C2=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
O=S(=O)(NC1(CCC1)C1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1)C1=CC=CC=C1
[H]C1=C([H])C(=C([H])C(Cl)=C1[H])[C@@]([H])(C#N)C1=NC2=C(C([H])=C1[H])C(=C([H])C(=N2)C(F)(F)F)C(F)(F)F
[H]C1=C([H])C(Cl)=C(S1)C1=NC(=NO1)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C1=C([H])C(=C(C([H])=C1[H])N1C(=O)C2=C(C([H])=C(Cl)C([H])=C2[H])C1=O)C([H])([H])[H])C1=C([H])C([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
COC1=CC2=C(CN(C[C@]3(NC(=O)NC3=O)C#CC3=CC4=C(C=C3)C(=NN4)C3=CC=NC=C3)C2=O)C=C1
[H]OP(=O)(O[H])[C@]([H])(C(=O)C1=C(C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC1=NC(=C(N1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]OC(=O)C1=C([H])N(C2=C(C([H])=C(F)C(=N2)N2C([H])([H])[C@]([H])(N([H])[H])[C@]([H])(C3=C([H])C([H])=C(O[H])C([H])=C3[H])C2([H])[H])C1=O)C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@@]12C([H])([H])C([H])([H])C(=O)[C@]3([H])OC4=C(OC([H])([H])[H])C([H])=C([H])C5=C4[C@]13C([H])([H])C([H])([H])N(C([H])([H])C1([H])C([H])([H])C1([H])[H])[C@]2([H])C5([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])[C@@]2([H])C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C([H])=C3[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])[C@@]2([H])C([H])([H])OC([H])([H])C2([H])[H])[C@@](O[H])(C([H])([H])[H])[C@]1([H])O[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])[H])C(=S)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C(F)C([H])=C2[H])=N1
[H]C1=NC2=C(C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1Cl)C1=C([H])C([H])=C(C(=O)N2C([H])([H])[C@]3(C([H])([H])[H])C([H])([H])[C@@]2([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C(Cl)=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])OC1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])[C@@]([H])(N1C([H])=NC([H])=C1[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(SC2=NC([H])=C([H])N2C([H])([H])[H])C(Cl)=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(\C([H])=C(/[H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])C([H])=C12
[H]C1=NC([H])=C([H])C(=C1[H])C(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=N2)C([H])([H])C([H])([H])C2=C1C([H])=C([H])C(Cl)=C2[H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H]
NC1=NC(O)=CC(=N1)C1=CC(C#N)=C(OCC2=CC=C(C=C2)C(O)=O)C=C1
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])C#CC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]1([H])OC([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])=C(OC([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C(=O)OC([H])([H])[H])C(=O)OC([H])([H])[H])C([H])=C2[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])C([H])([H])N(C([H])([H])C(=O)N([H])C3=C([H])C([H])=C(SC4=NN5C([H])=C([H])C([H])=C5C(=N4)N([H])C4=NN([H])C(=C4[H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(\N=C(/[H])C1=C(C([H])=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H])C(=S)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C(Cl)C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC([H])=C(SC([H])([H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])S1
[H]N(C([H])([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@]1([H])OC1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC([H])=C(C([H])=N1)N(C([H])([H])[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1[H])C(=O)O[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F