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[H]N1N=C(C#CC2=C([H])C([H])=C([H])N=C2[H])C2=C([H])C([H])=C([H])C([H])=C12
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[H]N(\N=C(/[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O)C(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N([H])C1=C(N=C(N=C1N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C#N)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C1(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2N1[H])C(=N[H])N([H])[H]
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[H]ON([H])C(=O)C([H])([H])[C@]([H])(C1=NC(=NO1)C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(F)(=O)=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NC([H])=C2C([H])=C([H])C([H])=C([H])C2=N1)[C@@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2F)C2=C([H])C([H])=C([H])C([H])=C2N([H])C1=O
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])S[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N=C(N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C3N(C(=NC3=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=C(/[H])C2=C([H])C([H])=C([H])C(N([H])[H])=C2[H])\C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])N1C(=O)N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])N(C(=O)C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])[H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(N([H])C(=N[H])N([H])[H])=C([H])C([H])=C2[H])C(=C1[H])C(F)(F)F
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C(C([H])=C2N1S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(N=C(N1[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])N=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])SC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]1(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]C([H])([H])C1=NC(=NC(=C1C(=O)N1C([H])([H])C([H])([H])C(N2C([H])([H])C([H])([H])[C@]3(OC(=O)N(C([H])([H])C4([H])C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C([H])([H])[C@]3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(O1)C([H])([H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(F)=C(C([H])=C1[H])C1=NC2=C(S1)N=C(C([H])=C2[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1N1N=C(C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(F)(F)F)[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)C1=C([H])C([H])=C(C(=C1[H])C1=NC2=C(C([H])=C1[H])C1(C(=O)N2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C3N=NN(C3=N2)C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1N=C(C2=C(N=NS2)C([H])([H])[H])\C(=C(/[H])C2=C([H])N(C3=C([H])C([H])=C([H])C(Cl)=C23)C([H])([H])[H])C1=O
[H]C1=C([H])N(C([H])=N1)C1=NN(C(=O)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(N=C(N([H])C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3OC([H])([H])[H])C([H])=C2[H])C(=N1)N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[S@@](=O)[C@@]2([H])C([H])([H])N(C(=O)[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]12[H]
[H]SC([H])([H])[C@]1(C(=O)N([H])[C@]([H])(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])[C@]([H])(OC1=C(Cl)C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(OC(=O)N([H])C3=C2C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])[C@@]1([H])C2=NC([H])=C(N2C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C(F)=C2F)C([H])([H])C1([H])[H])[C@]1(OC([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C([H])C([H])=N1)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C#N)C1=C(C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=N2)C(F)(F)F)C([H])([H])C1([H])[H]
[H]N([H])C(=O)[C@]([H])(N([H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NN=NN1C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C2C(OC([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])N1N=C(Cl)C([H])([H])C([H])([H])C1=O)C(=O)[C@@]([H])(C(=O)N2C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])=C1[H]
[H]OC([C@@]1([H])ON=C(C(=O)N([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C1([H])[H])(C(F)(F)F)C(F)(F)F
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[H]N1C([H])=C(C2=C1C(=O)N(C(=O)N2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)C([H])([H])[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C3=C(N=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N(C1=C(Cl)C(=C(Cl)C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])N2C(Br)=C(N=C12)C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])C1=C(OC2=C3C([H])=C(SC3=C([H])N=C2[H])C(=O)N([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC(C1=C([H])C([H])=C(C([H])=N1)C1=NC(=NC([H])=C1[H])N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])C([H])([H])N(C([H])([H])[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1O2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC1=NC(OC([H])([H])C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])[H])=N1)C(OC([H])([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(OC1([H])[H])C([H])=C([H])C([H])=C2[H])C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2N([H])[H])C(=N[H])N([H])[H])C(N([H])[H])=C1[H]
[H]N([H])C1=C(C2=NC3=C(N2[H])C([H])=C([H])C(=C3[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(=O)N([H])C2=C(F)C([H])=C([H])C([H])=C12
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)C([H])([H])N(C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]N(C(=O)[C@]1([H])N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C([H])C(N([H])C([H])([H])[H])=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC1=C([H])C(C#CC2=NC(=C([H])C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=O)C2=C(O1)C([H])=C([H])C([H])=C2OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H]
[H]N(C(=O)C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C1=C2C(=C([H])C([H])=C1[H])C1=NN([H])C(C3=C([H])SC(C#CC([H])([H])OC4=C([H])C([H])=C([H])C([H])=C4[H])=C3[H])=C1C2([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])N=C2N(C(=NC2=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC2=C(C([H])=NC3=C2C([H])=C([H])C([H])=C3[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(SC([H])(C(=O)N([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(Cl)N=C2N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C(=O)C1=NC([H])=C([H])S1
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])P(=O)(O[H])O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
CN1C(\C=C\C2=CC=C(Cl)C=C2)=CC2=C1C(=O)N(C)C(=O)N2C
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C([H])C2=C([H])C([H])=C([H])C(OC([H])([H])C3=C([H])C(=C([H])C([H])=C3[H])C(F)(F)F)=C2C([H])=C1[H]
[H]C1=C([H])C([H])=C(O1)C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)N([H])C2=NC(=C(S2)C(=O)C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C2([H])[H])C1([H])[H]
[H]N=C1N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2N1C([H])([H])C(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=N3)C([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C12)C([H])([H])[H])C([H])([H])[H]
ON(=O)C1=CC=C(CN2C=CN=C2)C(OC2=CC=CC=C2)=C1
[H]OC(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]O[C@@]1([H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C2=C(N([H])C([H])([H])C([H])([H])F)C(=O)C([H])=C(N([H])C(=O)\C(=C(/[H])\C(\[H])=C([H])/[C@]([H])(OC([H])([H])[H])[C@@]([H])(OC(=O)N([H])[H])\C(=C([H])\[C@]1([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O
[H]N([H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1Cl)C(=O)N([H])[C@]1([H])C([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)O[H]
[H]N1C(=NC2=C1C([H])=NC([H])=N2)C([H])([H])OC1=NN(C(=C1[H])C1=NC2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C(F)(F)F)C1=C([H])C(=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C(=C1[H])C1=NC([H])=NC2=C1SC(=C2[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N1C(=NC2=C1C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C21)C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2C2=NN=C([H])N2[H])C2=C([H])N=C([H])C([H])=C12)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1Cl
[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=NC(N([H])C3([H])C([H])([H])C([H])([H])N([H])C([H])([H])C3([H])[H])=C([H])N=C2C([H])=C1[H]
[H]N(C1=C2SC(=C([H])C2=NC([H])=N1)C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C(Cl)=C1[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=NC([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]O[C@]([H])(C([H])([H])F)C([H])([H])N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])[H]
[H]C1=C(OC(=C1[H])C([H])([H])N1C(=O)[C@]([H])(OC2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C([H])=C(C([H])=C2[H])C([H])([H])[H]
[H]N1\C(S\C(=C(\[H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C1=O)=N/C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
CCCCCCCCN1C=C(CN2CCN(C)CC2)C2=CC(=CC=C12)C1=CC(C)=CC=C1
[H]C1=NN2C(N=C(C3=C2C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])=C1C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])S[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N1C(=C([H])C2=C(C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC(=NO1)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C(=O)C1=C(N2N=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])[H]
[H]N1N(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1=O
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]O[C@@](C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])(C([H])([H])[H])C(F)(F)F
[H]C([H])=C([H])C([H])([H])SC1=NN=C(O1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N=C(N([H])[H])C1=C([H])C([H])=C(OC([H])([H])[C@@]2(OC3=C([H])C(=C([H])C([H])=C3N(C([H])([H])[H])C2([H])[H])N(C(=O)C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C2C([H])=C(C([H])=NC2=N1)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1OC([H])([H])[H]
[H]N(C(=O)N([H])C1=NC2=C(C([H])=NC(=N2)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])=C([H])C1=C2C([H])=NN1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C([H])C(O[C@@]3([H])C([H])([H])OC([H])([H])C3([H])[H])=C12)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1Cl
[H]N(C(=O)C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(OC2=C([H])C(Cl)=C(C#N)C([H])=C2[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC1(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]N(C1=C([H])C(=O)OC2=C([H])C([H])=C(Cl)C([H])=C12)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3C([H])=C([H])N([H])C3=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])F
[H]C1=C([H])C(F)=C(C(=O)N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])C3=C(N(N(C3=O)C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C(F)=C1[H]
[H]OC([H])([H])C(N1C([H])([H])C([H])([H])N(C(=O)OC2(C([H])([H])C2([H])[H])[C@]2([H])N([C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1C([H])=C([H])C([H])=C2C([H])([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1[H]
[H]C1=C([H])C([H])=C2C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C(Cl)C(Cl)=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])=C([H])C2=N1
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@]([H])(C(\[H])=C(/[H])C2=C(C3=C([H])C([H])=C(F)C([H])=C3[H])C3=C([H])C(F)=C([H])C([H])=C3N=C2C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]OC1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)C1=C([H])N(C(=O)C(C#N)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C#N)C1=NC([H])=C([H])N1C([H])([H])[C@@]([H])(C1=C([H])C(OC([H])([H])C([H])([H])C2([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C2=C(N([H])C(=N2)C2=C([H])C([H])=C(Cl)S2)C([H])=C1[H])C1=C([H])C([H])=C(N2C(=O)C([H])([H])OC([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@](O[H])(C([H])([H])N1C([H])=C([H])C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C(F)(F)F
[H]C1=C([H])C(F)=C([H])C(=C1[H])C1(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC2([H])C([H])([H])C([H])([H])N(C3=NN=C(N3C3=C([H])C([H])=C(OC([H])([H])[H])N=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])=C(C(F)=C1[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])[C@]2([H])C([H])([H])[C@@]1([H])C([H])([H])[C@@]2([H])N([H])C1=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2N=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N(C([H])([H])[H])S(=O)(=O)C2=C3C([H])=C([H])N=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(OS(=O)(=O)C3=C4C([H])=C([H])N=C([H])C4=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C([H])C(=N1)N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])C([H])([H])[C@@]2(C3=C(C([H])=C(Cl)C([H])=C3[H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H]
[H]OS(=O)(=O)C1=C([H])C([H])=C(O1)C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OS([O-])(=O)=O)C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C2C(N([H])C([H])=C2[C@@]2([H])N(N=C(C2([H])[H])C(F)(F)F)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(F)C1([H])[H]
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(C([H])([H])N([H])C(=O)C1=NO[C@]2(C1([H])[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C1=NC3=C(N1[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC2=NS(=O)(=O)C([H])([H])C([H])([H])N12)C(=O)OC([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC(=NC(=N1)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C(Cl)C2=C(S1)C([H])=C(Cl)C([H])=C2[H])C1=NC([H])=C([H])S1
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(C#N)(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C1=C([H])C(=C([H])C2=NC(=NN12)C1=C([H])C([H])=C(Br)O1)C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])O[C@@]1([H])C([H])([H])C([H])([H])[N@]2C(=O)O[C@]1([H])C2([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C(Br)=C([H])C(=C1[H])C1=NN=NN1C([H])([H])[H]
[H]OC(=O)C(F)(F)C1=C([H])C([H])=C(OC2=C(N([H])S(=O)(=O)C3=C(Cl)C([H])=C(Cl)C([H])=C3[H])C([H])=C(C([H])=C2[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NC(=C2N1C1=NC(OC([H])([H])[H])=C([H])C([H])=C1N=C2C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C(=O)C3=C([H])C([H])=C(C([H])=C23)C([H])([H])N([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(C(=O)N(C([H])([H])[H])C([H])([H])[H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)N1N=NC(=C1[H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])N([H])N=N1)C1=C(SC([H])=C1[H])C(=O)OC([H])([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=NN([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(N=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C2C([H])=C([H])C(\C([H])=C(/[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C([H])C2=NC([H])=C1C#N
[H]N([H])C1=NN2C([H])=C(C([H])=C([H])C2=N1)C1=C([H])N=C([H])C(=C1[H])S(=O)(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N2C([H])([H])C([H])([H])O[C@]12[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C2OC([H])([H])C(=O)N([H])C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)C([H])([H])OC3=C([H])C([H])=C(F)C([H])=C23)C([H])([H])C1([H])[H]
CCCC(=O)N1CCCN(CC1)C1(C(=O)NC(=O)NC1=O)C1=CC=C(OC2=CC=CC=C2)C=C1
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NOC2=C1C([H])=C(C([H])=C2[H])N1N=C(C2=C1C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C(F)(F)F
[H]N([H])S(=O)(=O)OC1=C([H])C2=C(C([H])=C1C([H])([H])C([H])=C([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]3(C(=O)C([H])([H])C([H])([H])[C@@]3([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C(=N1)C(=O)N([H])C([H])([H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C([H])([H])[C@@]2([H])N(C3=C(C([H])=C([H])C(Cl)=N3)C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
OC(=O)C1=CC=C(C=C1)C1CCN(CC1)C1=NC=C(S1)C(O)(C(F)(F)F)C(F)(F)F
[H]N([H])C(=O)C1=C([H])N=C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])N(C([H])([H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]O[P@@](=O)(C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(C(=O)N([H])[C@]1([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[N+]([H])([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]OC1=C([H])C([H])=C(OC([H])([H])[H])C(N([H])C(=O)N([H])C(=O)C2=C(Cl)C([H])=C(F)C([H])=C2[H])=C1[H]
[H]N(C1=NC([H])=C2C([H])=C(C(=O)N(C2=N1)C([H])([H])[H])C1=C(F)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])=C(C2=C([H])C(=O)N3C([H])([H])[C@]([H])(O[C@@]([H])(C4=C([H])C(=C([H])C(=C4[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]([H])(C4=C([H])C([H])=C(F)C([H])=C4[H])[C@]3([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=C3C([H])=C(OC([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]1(OC(=O)\C(=C(\[H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C1([H])[H])C([H])([H])OC(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(OC2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N1N=C(N(\N=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C1=S)C1=C([H])N=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])C(=O)C2=C(OC([H])([H])[H])C(O[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2O1
[H]OC1=C(C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2O1)C(=N[H])N([H])[H]
[H]OC(=O)C1=C(C(C#N)=C(N1C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1\C([H])=C(/[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H])C(=N[H])N([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])=C(C2=C([H])C([H])=C(OC([H])([H])[H])N=C12)C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=NC2=C([H])C(Cl)=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1(N([H])C(=O)C2=C([H])C(F)=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]N1N=NC([H])=C1C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C1=NC2=C(S1)N=C(SC([H])([H])[H])N=C2N([H])C1=C([H])C([H])=C(C(Cl)=C1[H])C(F)(F)F)C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])=C(C(=NC1=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=NN=C(C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])S1
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]2([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]3(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])SSC2([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C3([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])[H]
[H]OC([H])([H])C1=C([H])C2=C(N=C(S2)C(=O)[C@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@]([H])(N([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2F)C2=C([H])C([H])=C([H])C(=C2N(C1=O)C([H])([H])C(=O)N1C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NN([H])N=N1
[H]N(N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2OC1=O
[H]N([H])C1=NC(=C([H])C(=N1)C(=O)N([H])C([H])([H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])[H]
[H]N1C2=C(C(=O)C3=C([H])C([H])=C([H])C([H])=C23)[C@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C(C#N)=C1C([H])([H])[H]
[H]N([H])S(=O)(=O)N([H])C1=NN=C(SC([H])([H])[H])S1
[H]N1C(=O)N([H])C2(C3=C([H])C([H])=C([H])C(Cl)=C13)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])N=C([H])N1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C(=C1[H])C1=C([H])C(=NC([H])=C1[H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC2=C(C([H])=NC3=C2C([H])=C([H])C([H])=C3[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C(N2N=C(OC([H])([H])[H])C(N(C([H])([H])C([H])([H])C([H])([H])[H])C3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C2S1)C1=C(OC([H])([H])[H])C([H])=C(Cl)C([H])=C1OC([H])([H])[H]
[H]C1=C([H])C(Br)=C(C([H])=C1[H])[C@]1([H])OC2=C(N=NC(SC([H])([H])[H])=N2)C2=C(C([H])=C([H])C([H])=C2[H])N1C(=O)C([H])([H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1N=C([H])C(C#CC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C1[H]
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C([H])=C(OC(F)(F)F)C(Cl)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
N[C@H](CC1=CC=CC(F)=C1)C1=NC2=CC=C(C=C2C(=O)N1)C1=CNN=C1
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])N=C(C([H])=C1[H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])C(=O)C([H])([H])[H])C([H])=O
ON(=O)C1=CC2=NC3=C(CCCC3)C(NC3=CC=CC=C3)=C2C=C1
[H]N1C(=C([H])C(C#N)(C#N)C(C#N)(C#N)[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)C2=NN(C(=O)N2C2=C1N=C([H])C([H])=C2[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C(=C1[H])C1=NOC(=N1)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N([H])C1=N[C@]([H])(C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])C([H])([H])C1([H])[H])[C@]([H])(C#N)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[H])N([H])[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(C(=O)OC([H])([H])[H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@@]([H])(N2C([H])=C(C3=C([H])C([H])=C(F)C([H])=C23)S(=O)(=O)C2=C([H])C([H])=C([H])C(F)=C2[H])C1([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
CCCCCCCCOC1=NO[N](O)=C1S(=O)(=O)C1=CC=CC=C1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])OC(=O)C1=C([H])C(O[H])=C(C(=O)C2=C(N([H])C(=O)C([H])([H])[H])C([H])=C([H])C([H])=C2O[H])C(O[H])=C1[H]
[H]OC(=O)[C@]1([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[H])C([H])([H])C2=C(C3=C(N2[H])C([H])=C([H])C([H])=C3[H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(OC2=C(C([H])=C([H])C(OC3=C([H])C(=C([H])C([H])=C3[H])C(=N[H])N([H])[H])=N2)C(=O)N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(C(=O)C(\[H])=C(/[H])C2=C([H])C(O[H])=C(O[H])C([H])=C2[H])=C(O[H])C([H])=C1[H]
[H]N1C([H])=C(C2=C([H])C(Br)=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
COC1=CC=C2C(SC3=C2N=CN=C3NC2=CC=CC(C)=C2)=C1
[H]N(C(=O)C1=C(N(N(C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])N=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1[H]
[H]C1=C([H])C(C#N)=C(Cl)C([H])=C1N(C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C2C(=NC3=C(C(=NN13)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C(S2)C2([H])C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(O[H])C([H])([H])OC3=C([H])C([H])=C([H])C4=C3C([H])=C([H])N4[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])N([H])C1=C2C([H])=C(C#CC([H])([H])N([H])C(=O)C3=C([H])C([H])=C([H])N(C3=O)C([H])([H])C3=C([H])C([H])=C(F)C(F)=C3[H])C([H])=C([H])C2=NC([H])=N1
[H]OC([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N1C2=C(OC([H])([H])[C@@]1([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(N([H])C(=O)C([H])=C1C(F)(F)F)C([H])=C2[H]
[H]O[C@@]([H])(C([H])([H])S(=O)(=O)[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])N([H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]ON([H])C(=O)C1=C([H])C(Br)=C([H])C(=C1N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(N(C([H])([H])[H])C([H])([H])[H])=C2C(SC3=C2N=C([H])N(C3=O)C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=N1
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N([H])C(=O)C(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)C2=C([H])C([H])=C([H])C3=C2C([H])=C([H])N3C([H])([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C(F)=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
CC(C)C1=CC=CC(C)=C1C(=O)N[C@@H](CC1=CC=C(C=C1)C1=C(C=C(C)N(C)C1=O)C(F)(F)F)C(O)=O
[H]N(C(=O)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C1C([H])=C([H])C(Cl)=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=NC(=NC([H])=C1F)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(OC(=O)C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]([H])(O[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(O[C@]2([H])C([H])([H])N(C([H])([H])[H])[C@@]([H])(C(=O)N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C3([H])[H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C2([H])[H])=C([H])C([H])=C1F
[H]N(C1=NC2=C([H])C([H])=C(N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C2N2C([H])=NC([H])=C12)C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(C1=NN=NN1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
NC(=O)N1CCC2=C(C1)C(=NN2CCCN1CCN(CC1)C1=CC=CC=C1)C1=CC(C#CC2=CC=C(CNCC3=CC=C(Cl)C=C3)C=C2)=C(Cl)C=C1
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N2C(=NC(=C(C(=O)OC([H])([H])[H])[C@]2([H])C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])=C(C(=O)C2=C([H])C(N([H])C([H])(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1N=C(F)C2=C1C([H])=C([H])C1=C2C([H])([H])[C@]2(C1=C(Cl)C(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(OC([H])([H])C([H])([H])C2=C([H])N([H])C4=C2C([H])=C(Br)C([H])=C4[H])N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N1N=C(OC1=C1C([H])=C([H])C(=O)C([H])=C1[H])SC([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(SC2=C(C([H])=C(Br)C([H])=C2[H])C([H])([H])OC([H])([H])[H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])C2=NC(=C([H])C([H])=N2)C2=C([H])N=C(N2C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=NO1)C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N3C([H])([H])C([H])([H])N(C4=C([H])C([H])=C([H])C([H])=C4Cl)C([H])([H])C3([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C([H])([H])[C@]1([H])O[C@@]([H])(C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C([H])=C2N=C(C([H])=C12)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(Cl)C([H])=C2[H]
[H]N1C(=NC2=C1C([H])=C(C([H])=C2Cl)C(F)(F)F)C([H])([H])OC1=NOC(=C1[H])C1=NC2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])C1=C([H])C2([H])C3([H])OC4(OC3(C(=C([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C2(O4)C2([H])C([H])=C(C(=O)C2(O[H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C3=C([H])C([H])=C(O[H])C([H])=C3[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])SSC1([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(C2=C(S1)C(Br)=C([H])S2)C([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C([H])C(N([H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])N=C2C([H])=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])N=C2C(OC2=NC3=C(N=C(N(C3=O)C([H])([H])[C@]3([H])C([H])([H])N(C([H])([H])C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC(=N1)C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])[C@@]([H])(C2([H])[H])[C@]1([H])C([H])([H])[H]
[H]OC1=C2O[C@@]3(C(=O)C([H])([H])C([H])([H])[C@]4(OC([H])([H])[H])[C@@]5([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]34C2=C(C([H])=C1[H])C5([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=NN([H])C(=C2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C#N)C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2S1)C1=C([H])C([H])=C2N=C(C([H])=C(C2=C1[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
OC(COC1=CC=CC=C1)CN1CCN(CC1)C1=NC=NC2=C1C(=CS2)C1=CC=C(F)C=C1
[H]C1=C([H])N(C(C#CC2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(SC2=C([H])C([H])=C(F)C([H])=C2F)=C([H])N2C1=NN=C2C1=C([H])C([H])=C(F)C([H])=C1F
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C2=C1N(C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C2([H])[H])C([H])([H])[H]
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[H]N([H])N([H])C(=O)C([H])([H])SC1=NC2=C(C3=C(S2)C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C(=O)N1C1=C([H])C([H])=C([H])C(F)=C1[H]
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[H]O[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C(N([H])C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H])[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OP(=O)(O[H])C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]\C(C([O-])=O)=C1/C(=O)N2[C@]1([H])S(=O)(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([O-])=O
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[H]OC1=C(N([H])C2=C([H])C([H])=C(C#N)C([H])=C2O[H])\C(=N\C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
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[H]N([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(/C([H])([H])N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N1C([H])([H])C([H])([H])O[C@@]([H])(C1([H])[H])[C@]([H])(OC1=C(Cl)C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])SC([H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]C1=NC([H])=C([H])C(=C1[H])C(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]1([H])C(=O)C([H])([H])C([H])([H])N(C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C(Br)=C2[H])C1([H])[H]
[H]N1N=C(C2=C([H])N([H])C(=C2[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(N([H])C2=C(N([H])[C@@]([H])(C3=C([H])C([H])=C(O3)C([H])([H])[H])C(F)(F)C([H])([H])C([H])([H])[H])C(=O)C2=O)C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])S(=O)(=O)N1C([H])([H])[C@@]2([H])C(=O)N(C3=C([H])C([H])=C(OC(F)(F)F)C([H])=C3[H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC1=NC(=C(N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C([H])=C(C(=C1[H])N(C1=NC(=C([H])C(=N1)C([H])([H])[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(F)(F)F)N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C([H])=C(N([H])C2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(SC([H])([H])C([H])([H])C([H])([H])[H])=NN=C1C(F)(F)F
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])N([H])C2=C(C([H])=C([H])C(\C([H])=C(\[H])C([H])([H])C([H])([H])C3([H])C([H])([H])C([H])([H])N([H])C([H])([H])C3([H])[H])=C2[H])C([H])([H])N(C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=N\C1=C([H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C([H])C([H])=C3[H])C2=C1[H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C(C([H])=C([H])C([H])=C12)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(C2=C([H])C([H])=NN2C([H])([H])[H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]3([H])C([H])([H])C1=C2C(OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])SSC([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1N([C@]([H])(C([H])([H])[H])C([H])([H])OC(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(N([H])C([H])([H])C2=C(O[H])C(=NC([H])=C2C([H])([H])O[H])C([H])([H])[H])C([H])=C1[H]
CCCCN1CCCC[C@H]1[C@H](COC)c1ccccc1
[H]N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(\C(\[H])=C(/[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])=C(\[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])N1C2=NC(=C(N2C(=O)C(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])=C1C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N=C(S1)C([H])([H])[H])C1=NN=C(N1C([H])([H])C([H])([H])C(F)(F)F)C([H])([H])N1C(=O)C([H])([H])OC2=C(Cl)C([H])=C(Cl)C([H])=C12
[H]N(C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H])C1=NC(=NC2=C1N(N=C2C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C(F)(F)F)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N([H])C1=N[C@]([H])(C2=C([H])C([H])=C([H])O2)C([H])([H])C2=C1SC([H])=C2[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NC2=C(C(=NN2C2=C(Cl)C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C([H])([H])[H])C(=O)N1[H]
[H]C1=C(N=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N(C1=C(C([H])=NC(=N1)C#N)C(=O)N([H])[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]2(C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1O[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]1(O[H])C([H])([H])N([H])C([H])([H])[H]
[H]N(OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]C1=C(OC(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(\C([H])=C(/[H])C2=NC3=C(O[H])C(=C([H])C([H])=C3C([H])=C2[H])C(=O)O[H])=C([H])C([H])=C1O[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@@](=O)(O[H])O[P@](=O)(O[H])OP(=O)(O[H])O[H])[C@@]1([H])O[H])N1C([H])=C([H])C2=C(C([H])=C(F)C([H])=C2[H])C1=O
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])N(C(=O)[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C(O[H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])SC([H])([H])C([H])([H])[C@]1([H])C#N)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])N(N=N2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2N=NC(=C2[H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2OC([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C2([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]\C(=N/OC([H])([H])C(=O)N1C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])=NC(=C2[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]O[C@@](C(=O)N([H])C1=C([H])C([H])=C2C(=O)ON=C(C2=C1[H])C([H])([H])[H])(C([H])([H])[C@]1([H])C2=C(C(Cl)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(C#N)C(OC2=C(Cl)C([H])=C([H])C([H])=C2[H])=C1[H]
[H]OC1=C([H])\C(=N\C2=C3C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C3=NC([H])=N2)C(=O)C([H])=C1OC([H])([H])C1=C(F)C(F)=C(F)C(F)=C1F
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1[H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C#N)C(=C1[H])C(=O)C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])=C([H])[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])O[H])C([H])=C1[H])C(=O)O[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)C(=C(/[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(OC2=C([H])C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C3=O)=C(F)C([H])=C1F
[H]ON(C([H])=O)[C@]([H])(C([H])([H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])N=C([H])C([H])=C1SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(F)=C1[H])[C@@]1([H])C2=C(C([H])=C([H])C(Cl)=C2[H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N3C(=O)N(C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(SC([H])=C1[H])C(=O)OC1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)O[C@@]1([H])[C@@]([H])(OC(=O)C([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]23OC(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(C(=O)[C@@]([H])(OC(=O)C([H])([H])[H])[C@]12C([H])([H])OC(=O)C([H])([H])[H])[C@@]3([H])OC(=O)C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C(=O)C(\[H])=C1\C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12
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[H]N(\C([H])=C1/C([H])=C([H])C([H])=C(OC([H])([H])[H])C1=O)N1C(=S)N([H])N=C1C1=NN([H])C2=C1C([H])([H])C([H])([H])C2([H])[H]
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CCSC1=NC(=C(N1)C1=CC=C(C=C1)S(C)(=O)=O)C1=CC=C(F)C=C1
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[H]N(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C(=C2[H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(=C1[H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C(N(N=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C([H])([H])N(C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(C(Cl)=C2Cl)S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)[C@]([H])(O[H])C([H])([H])C(=O)[C@@]([H])(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)N([H])N([H])C(=O)C1=C([H])C(N([H])C(=N[H])N([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=NN2C([H])=C(C([H])=C([H])C2=N1)C1=C([H])N=C([H])C(=C1[H])S(=O)(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SSC1=C([H])C([H])=C([H])C([H])=N1
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[H]N([H])[C@]([H])(C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)C(SC([H])([H])C1=C([H])C([H])=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC2=C(S1)C([H])=C(Br)C([H])=C2[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C2=C1N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=C2C([H])([H])C(=O)OC1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@@]1(O[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@@]2(C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=C3C(=NC([H])=N2)N([H])C([H])=C13
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2OC([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=C(C(=C([H])C(=C1[H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2C(Br)=NN3[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C2=NOC(=N2)C([H])([H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C3=C(C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(Br)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C1=NC(N([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C2N=C([H])N(C2=N1)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])N(C(=O)C11C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C2=C(Cl)C([H])=C([H])C(Cl)=C2C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C2N=C(SC([H])([H])C(=O)OC([H])([H])[H])C3=C(C(=O)N(C3=O)C([H])([H])C([H])([H])OC(=O)C([H])([H])[H])C2=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C(=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=C([H])C(=C3[H])C(F)(F)F)N3C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N([H])C1(C(=O)N([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[C@@]([H])(N([H])[C@]3([H])C([H])([H])N([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2C([H])=C3OC([H])([H])OC3=C([H])C2=NC(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
CC(C)(C)OC(=O)N1CCN(CC1)C1=CN=C(OCC2=CC=C(C=C2)S(C)(=O)=O)C=C1
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(N(C3=C([H])C([H])=C([H])N=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(C(F)=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC(=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C3=NC([H])=C([H])C(=N3)N3C([H])=C([H])C4=C3C([H])=C([H])C([H])=C4N3C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[C@@]3([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]2([H])N(C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]([H])(C1=C([H])C2=C(C([H])=C1[H])C([H])=C(OC([H])([H])C1=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C1[H])C([H])=C2[H])C([H])([H])[H]
[H]N([H])C1=C(C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])[H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N=C2N1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C(=O)C3([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC(=O)C4=C([H])C(Cl)=C(N([H])[H])C([H])=C4OC([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
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[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1Cl)[C@@]([H])(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C(Br)C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(S1)C1=NN=C2SC([H])([H])C(=NN12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=N1)C(C1=C(C([H])=C(Cl)C([H])=C1[H])C([H])([H])C2([H])[H])=C1C([H])([H])C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C2=C(N1[H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C([H])([H])[H]
[H]N([H])C(=O)C1=C(N([H])[H])N(N=N1)C([H])([H])C1=C([H])C(Br)=C(Br)C(Br)=C1[H]
[H]S\C(=N\C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N([H])C1=NC([H])=C(Br)C(=N1)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)C([H])([H])OC(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(SC2=C([H])C([H])=C([H])C([H])=C2[H])N=C3N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C1(N([H])C(=O)C2=C([H])C(Cl)=NO2)C([H])([H])C1([H])[H])[C@@]([H])(C1=NC([H])=C(C([H])=C1F)C1=C([H])C(Cl)=C([H])C(Cl)=C1OC([H])([H])C([H])(F)F)C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(O[H])C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])N1C(=C(C(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=C([H])C(=NC([H])=N1)N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])N([H])C1=C([H])C(N([H])C(=O)C2=C([H])C(=C([H])C(=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(F)(F)F)=C([H])C([H])=C1C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(O[H])C([H])=C3[H])C([H])([H])SSC1([H])[H])C([H])([H])O[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC1=C(C(=O)N([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1Br
[H]OC1=C([H])C(N([H])C2=C(C(=O)N([H])C2=O)C2=C([H])C(=C([H])C([H])=C2[H])[N+]([O-])=O)=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C2=C([H])C([H])=C(C([H])=C2C2=C1C1=C(C3=C(C([H])=C([H])C([H])=C3[H])C1([H])[H])C1=C2C([H])([H])N([H])C1=O)C([H])([H])OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C1C([H])([H])C([H])([H])[C@]2([H])[C@]([H])(C3=C4OC([H])([H])C([H])([H])C([H])([H])C4=C(C([H])=C3OC2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C(=O)C1=C([H])C(=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]SC1=NN=C(N1N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=C(O)C=CC(\C=C\C=C\C(=O)C2=C(OC)C=CC=C2O)=C1
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])[C@@]2(N([H])[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)[C@@]22C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C2([H])[H])C1=O
[H]N(C(=O)OC1=C([H])C([H])=C2N(C3=C(C2=C1Br)C([H])([H])C([H])([H])\C3=N\C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N1C2=NC(N([H])C3=C([H])C(=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])C([H])([H])C3=C(C([H])=C([H])C1=C3[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])=C(Cl)C([H])=N2
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C(=O)OC([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)OC([H])([H])[H]
[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=C([H])C([H])=C2[N+]([O-])=O)N1C(=O)[C@@]2([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])[C@@]2([H])C1=O
[H]C1=NC(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])C([H])(N(C4=C([H])C([H])=C([H])C([H])=C4[H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(N=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(F)C([H])=C2F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2N=C(N=C2N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H])C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N1C([H])=C2C(=C1\C([H])=C1/C(=O)N([H])C3=C([H])C([H])=C(Br)C([H])=C13)C([H])([H])C([H])([H])OC2=O
[H]OC([H])([H])[C@@]([H])(N([H])C1=C(C([H])=NC([H])=C1[H])S(=O)(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C([H])C(C2=C([H])C([H])=C([H])S2)=C1C#N)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[C@]([H])(O[H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C(=C([H])C(=C1[H])C1=NN=NN1C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C2C([H])=C([H])C(O[C@@]3([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C2=C([H])C([H])=N1
[H]N(C1=C([H])C(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(C([H])=C1[N+]([O-])=O)[N+]([O-])=O)C([H])([H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C(O1)C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C(C(OC2=C([H])C([H])=C3SC([H])([H])C([H])([H])C3=C2[H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@@]([H])(C#N)C1=C([H])C([H])=C([H])N=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H][C@@]12CC3=C(CN1CCC1=CC4=C(OCCO4)C=C21)C(OC)=C(O)C=C3
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[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C(F)C([H])=C(C([H])=C1F)N(C([H])([H])[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1[H])C(=O)O[H]
[H]OC(=O)C([H])([H])N1C(=O)S\C(=C(\[H])/C(/[H])=C(\[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1=O
[H]C1=NC(=NC([H])=C1N1C(=O)C(Br)=C(OC([H])([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]2([H])C3=C(C([H])=C([H])C([H])=N3)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]1([H])O[C@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@@]([H])(O[H])[C@@]1([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])N1N=NN=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(Br)C([H])=N1
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=NC2=C([H])C(Cl)=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C2O[C@@]3([H])C(=O)C([H])([H])C([H])([H])[C@@]4(N([H])C([H])([H])C([H])([H])C5=C([H])C([H])=C(Cl)C([H])=C5[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N1C([H])([H])C2=C(N(C3=C([H])C(=C([H])C([H])=C23)N2C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C([H])C2=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C2=C(OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])=NC([H])=C2S1
[H]N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\[H])C3=C(C4=C(N3[H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N([H])C([H])([H])C3([H])[H])C2=C1[H]
[H]N1C(=O)C([H])([H])OC2=C([H])C([H])=C(C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3C([H])=C([H])C(=NC3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)C([H])([H])N1C(=O)[C@@]([H])(N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C3C([H])=C([H])C(OC([H])([H])[H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N1N=NC(=N1)C1=C([H])N=C(S1)N1C([H])([H])[C@@]2([H])C([H])([H])N(C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3Cl)C([H])([H])[C@@]2([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(OC3=C(C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])[H])S2(=O)=O)=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N3C([H])([H])C([H])([H])N(C4=C([H])C([H])=C([H])C(=N4)C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(O[H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C3=NN4C(S3)=NC(=C([H])C4=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C(=O)[C@@]2([H])N3C4=C(C([H])=C([H])C([H])=C4C2([H])[H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C4=C(OC([H])([H])C4([H])[H])C([H])=C2[H])C3=O)C([H])([H])C1([H])[H]
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[H]N(C1=C2N([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C1=C(C#N)C([H])=NC([H])=C1C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C2C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C(S1)C1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=N1
[H]N1C(=O)OC([H])([H])[C@@]1([H])C(=O)N1C([H])([H])[C@@]([H])(O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
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[H]C([H])=C([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C2N(C(=O)N=C(C3=C([H])C([H])=C(C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])OC1=NN=C(O1)C1=C([H])N2N=C([H])N=C(N([H])C3=C(F)C([H])=C(F)C(=C3[H])C(=O)N([H])C3([H])C([H])([H])C3([H])[H])C2=C1C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C2C([H])=C(C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C1[H]
[H]OC1=C(\C([H])=N\N=C(/S[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]OC1=NC2=C([H])C(Cl)=C([H])C([H])=C2N2N=C(N=C12)C(=O)N([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@]1(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2F)C([H])([H])C2=NN([H])C(=O)C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]C1=NC(=C(C([H])=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C(=N/OC([H])([H])[H])\C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])[H]
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[H]N1C2=C(C([H])=C([H])C(=C2[H])C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CC[C@@H](NC1=NC(NCC2=C(O)C=CC(F)=C2)=C2N=CN(C(C)C)C2=N1)C(C)O
[H]OC(=O)C1=C(Br)C(Br)=C(Br)C(Br)=C1S(=O)(=O)N([H])C(=N[H])OC([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C(C([H])=C1S2(=O)=O)C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C([H])([H])C(=O)N1[C@]([H])(C(=O)O[H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])N(C(=O)C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C1=NN(C(=O)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=NOC(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]12C(=O)N(C(=O)[C@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\[H])C3=C(C4=C(N3[H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C([H])([H])C(=O)N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C2=C1[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1=NC([H])=C(F)C([H])=N1)C([H])([H])C1=C([H])C(=C(F)C([H])=C1[H])C(F)(F)F
[H]N1C2=C([H])C([H])=C([H])C([H])=C2N=C2SC(=C([H])C2=C1N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C2=C(O1)C(OC([H])([H])[H])=C([H])C([H])=C2C([H])([H])N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=C(C#N)[C@@]([H])(C2=C(Cl)C([H])=C([H])C([H])=C2[H])C(C(=O)OC([H])([H])[H])=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C([H])=NC2=C(N=C(N=C12)C#N)N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(C([H])=C([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])N2C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1[H])[C@@]([H])(N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H])C1=NN=NN1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=O)N=C2C([H])=C([H])C(=NN12)N1C([H])([H])C([H])([H])[C@]([H])(C2=C(F)C([H])=C(F)C(F)=C2[H])[C@@]([H])([N+]([H])([H])[H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(\N=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C(C([H])=C(C([H])=C3[H])C3=NC4=C(S3)C([H])([H])C([H])([H])C([H])([H])O4)C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C2=C1N(C(=O)S2)C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=NC(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])C1=C([H])C2=C(C([H])=C1[H])N(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]C([H])=C([H])C([H])([H])OC1=C([H])C([H])=C(\C([H])=N\N([H])C2=C3C([H])=NN(C3=NC([H])=N2)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=NC(=C([H])C([H])=N2)C2=C([H])C([H])=C(N([H])C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(=O)C1=NC(=C([H])C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])[H]
[H]N(\C([H])=C1/C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])=C([H])C2=NC([H])=NC(N([H])C3=C([H])C([H])=C(OC4=C([H])C([H])=C([H])C5=C4C([H])([H])C(=O)N5[H])C(Cl)=C3[H])=C12
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[H]OC1=C2C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C([H])C2=NC(=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(OC([H])([H])[H])[C@]2([H])N(C([H])([H])[H])C([H])([H])[H]
CCC1=CC2=C(CC(C2)NC[C@H](O)C2=C3CCC(=O)NC3=C(O)C=C2)C=C1CC
[H]N([H])N1C(SC([H])([H])C(=O)N([H])C2=NOC(=C2[H])C([H])([H])[H])=NN=C1[C@@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])C([H])([H])[C@@](O[H])(C2=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C(=C2[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
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[H]N(\C([H])=C1/C(=O)N([H])C2=C([H])C([H])=C3N=C([H])SC3=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC1=C([H])C([H])=C(\C([H])=N\N([H])C(=O)N([H])\N=C(/[H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]1(C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])N1C2=C(SC([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]3([H])N(C(=O)[C@@]4([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[C@@]([H])(O[H])C3([H])[H])C([H])([H])C3=C([H])C([H])=C([H])S3)C([H])([H])O[H])C1=O)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])[C@@]([H])(C#N)N1C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=NC([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=C(C([H])=NN1C([H])([H])[H])C(=O)N([H])C1=C([H])C2=C(OC(F)(F)C(F)(F)O2)C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C3=C1C([H])=C([H])C([H])=C3[H])C(=O)N([H])[H])C([H])([H])C1=C(C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(\C([H])=C(/C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])C2=C([H])C([H])=NC([H])=C2[H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C1=C([H])SC2=C1C([H])=C([H])C([H])=C2[H])[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1OC(=O)C2=C1N(C1=C(C([H])=C(F)C(Cl)=C1[H])C2=O)C([H])([H])C([H])([H])[H]
[H]C1=NC(OC2([H])C([H])([H])C([H])([H])N(C3=C([H])C4=C(C([H])=N3)C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@]1([H])C(=O)N(C(=O)C1([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])[C@@]2(OC(=O)C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])[C@@]([H])(C(=O)N(C([H])([H])C2=C([H])C(=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C2([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)C1=C(OC(=N1)[C@]([H])(N([H])C(=O)[C@@]([H])(OC(=O)OC1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])\N=C(\C1=C([H])C(=C([H])C([H])=C1[H])C(=N\N([H])C(=N[H])N([H])[H])\C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(N([H])C2=C([H])C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[C@]4([H])OC(OC4([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2C3=O)C([H])=C([H])C([H])=C1[H]
OC1=CC=CC(\C=C\C(=O)NCC2=CC=CC=C2)=C1
[H]N([H])C1=NC([H])=C2C([H])=C(C(=NC2=C1[H])N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(Cl)=N1)[C@]([H])(OC1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC([H])=C(O1)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C([H])([H])N([H])C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C(=O)N([H])C(=O)C1([H])[H])C([H])([H])O[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])N(C([H])([H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N([H])C(=O)[C@@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)[C@@]2([H])OC3=C(C([H])=C(N([H])C(=O)OC([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(SC([H])([H])C2=C([H])C([H])=C(I)C([H])=C2[H])=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N2C(=S)S\C(=C(\[H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C2=O)=C1[H]
[H]C1=C([H])[C@]2(C(=C([H])C1=O)C([H])([H])C([H])([H])[C@@]1([H])[C@@]3([H])C([H])([H])OC(=O)[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H])C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]O[C@@]1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N1C([H])([H])C([H])([H])C2(N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])N([H])C2=O)C([H])([H])C1([H])[H]
[H]C1=NC(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C(=O)C([H])([H])OC([H])([H])C3=O)C([H])([H])C2([H])[H])=C(Cl)C([H])=C1[H]
[H]N(C1=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC1=C([H])C2=C3C(N([H])C4=C(C([H])=C([H])C([H])=C34)C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2C([H])=C1[H]
[H]N1C([H])=C(C2=C([H])C(=C([H])C([H])=C12)N1C([H])=NN=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=NC2=C3N1C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C2[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=NN([H])C(=C3[H])C3=C([H])C([H])=C(C#N)C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(C3=C([H])C([H])=C([H])C([H])=C3O[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])O2
[H]O[C@@]1([H])C([H])=C([H])[C@@]23C4=C(C([H])=C([H])C(OC([H])([H])[H])=C4O[C@@]2([H])C1([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C4C(O[C@@]5([H])C([H])([H])[C@@]([H])(OC([H])([H])[H])C([H])=C([H])[C@@]45C([H])([H])C1([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C3([H])[H]
[H]N([H])C1=NC([H])=C2C([H])=C(C(=O)N(C2=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC1=C([H])C([H])=C(C([H])=C1Br)C([H])(N1N=C([H])N=C1[H])C1=C([H])C(Br)=C(O[H])C([H])=C1[H]
[H]C1=C([H])N2C(S1)=N[C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C(OC([H])([H])[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])=C1[H])C2([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])C([H])([H])N1C(SC([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])=NN=C1C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])C1=C(Cl)C([H])=C(C(=O)OC([H])([H])C([H])([H])N2C([H])([H])C([H])=C([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N1C([H])=C(C2=C([H])C(Br)=C([H])C([H])=C12)C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=NC([H])=C2[H])C([H])=C1[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])OC([H])=N1
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C(Cl)C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=N1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C2=C1OC([H])([H])C([H])([H])O2)C1=NN=C(O1)C([H])([H])Br
[H]OC(=O)[C@@]1([H])N(C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])N(C3=C4C([H])=C([H])C([H])=C([H])C4=NC([H])=N3)C([H])([H])C2([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])[H]
[H]C1=C(N(N=C1C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C(N([H])C(=O)C(\[H])=C(/[H])C2=C([H])C(O[H])=C(O[H])C([H])=C2[H])C([H])=C1[H]
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[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N(C1=NC(=O)\C(S1)=C(/[H])C1=C([H])C([H])=C([H])N1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])C([H])([H])[C@]([H])(N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N([H])C(=O)C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C(N(C2=NC(=NC([H])=C2[H])N([H])C2=C([H])C(=C([H])C(=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
COC1=CC=C(CNC2=CC(O[C@H]3CCN(C)C3)=C(C=C2)C(F)(F)F)C=C1
[H]N1C(=O)C([H])([H])C([H])([H])C2=C1C([H])=C(OC([H])([H])C([H])([H])[H])C(=C2[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=S)SSC(=S)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C1=C([H])C(N([H])[H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C2=C([H])C(=C([H])C([H])=N2)C([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])S(=O)(=O)C1=C(Cl)N=C2SC([H])=C([H])N12
[H]N([H])C1=C([H])C(=NC(OC([H])([H])C([H])([H])OC([H])([H])[H])=C1C#N)N([H])C(=O)C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])OC3=C([H])C([H])=C([H])C([H])=C3OC2([H])[H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N([H])[C@]([H])(C1=C([H])C2=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=C(OC([H])([H])C4([H])C([H])([H])C4([H])[H])C([H])=C3[H])C(=C2N=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])C([H])([H])N(C(=O)C2=C(O[H])C([H])=C([H])C(SC3=C([H])N=C(S3)N([H])C3=C([H])C([H])=C([H])C(Br)=N3)=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NO[C@@](C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])N2N=NN=C2[H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C([H])C([H])=C(C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(N([H])S(=O)(=O)C2=C(SC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
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[H]N1C2=C(C3=C(C([H])=C([H])C([H])=C3[H])C1=O)C([H])([H])C1=C2C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]C1=C([H])[N+](=C([H])S1)C([H])([H])C1=C([H])C(OP([O-])(=O)OC([H])([H])[C@]([H])(OC([H])([H])[H])C([H])([H])OC2=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2[H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H])[C@]([H])(C(=O)N1C([H])([H])C2=NN=C(N2C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])=C([H])[H]
[H]N(C1=NC([H])=C2C(=O)N(C3=NC4=C(C([H])=C([H])C([H])=C4[H])N3C2=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=NC2=C1C([H])=C([H])N2C([H])([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])N(N=C1[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])N1N=C(C([H])=C1N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)S\C(=C(\[H])C2=C([H])C([H])=C(OC3=C(C([H])=C(C([H])=C3[H])C(=O)OC([H])([H])[H])C(F)(F)F)C(OC([H])([H])[H])=C2[H])C1=O
[H]OC1=C(N([H])C2=N[S@](=O)N=C2N([H])C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C2=NC([H])=C(C(=N2)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1Cl)S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
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[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C(C(=NC2=C([H])C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
C1CN=C(N1)C1COC(CO1)(C1=CC=CC=C1)C1=CC=CC=C1
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C2N=C(N([H])C2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]OC1=C2C(=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C(O[H])=NC1=C([H])C(Cl)=C([H])C([H])=C21
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[H]N(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2N(C(SC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C(=C3[H])[N+]([O-])=O)=NC2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(OC([H])([H])C1([H])[H])C([H])=C([H])C(=C2[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[N+]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C1=NC(=NC2=C(C(=NN12)C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(SC(=C2C([H])([H])C2=C([H])C([H])=C(C(=C2[H])C([H])([H])N([H])[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=C(/[H])C([H])([H])C1=C(O[H])C(=C(C(=C1OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])\C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C([H])=N1)C1=C(N=C2N1[C@]([H])(C([H])([H])OC([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=NC(=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C(N2C([H])([H])C([H])([H])C([H])(C(=N/OC([H])([H])C([H])([H])[H])\C3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])C(=O)N(C2=C(C([H])=C([H])C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(C(=O)N([H])C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C(=O)OC([H])([H])[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C(Cl)=C1F)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC(=C(C2=C([H])C([H])=C3N=C(N([H])C4=C(Cl)C([H])=C([H])C([H])=C4Cl)N(C3=C12)C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=NN(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C4=C3C([H])([H])C([H])([H])O4)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C(=O)\C(=C(/[H])C2=C([H])C([H])=C([H])O2)C1=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])C1=C([H])C([H])=C2N(C([H])=C([H])C2=C1[H])[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])S1
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[H]N=C(N([H])[H])C1=C([H])C(OC2=C(F)C(=C(F)C(OC3=C([H])C(=C([H])C([H])=C3[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])=N2)C([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([C@@]([H])(C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1Cl)C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1C(F)(F)F)C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=C(C([H])=C(C([H])=C3[H])C(F)(F)F)[C@@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H]
[H]C1=C2C3=C(N=C(C([H])=C3N(C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])N1C1=C(C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NOC2=C1C([H])=C(C([H])=C2[H])N1N=NN=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N(C1=NC([H])=C2N=C([H])N=C(N([H])C3([H])C([H])([H])C4=C(C([H])=C([H])C([H])=C4[H])C3([H])[H])C2=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC(=N1)N([H])[H])C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1Br
[H]OC(=O)[C@@]([H])(OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C2N(C([H])=NC3=C2C2=C(S3)C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C1=S
[H]N(C1=C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=NC([H])=C1[H])S(=O)(=O)C([H])([H])[H]
Cl.ClC1=CC=C(CN2CCC3(CCCC4=CC=CC=C34)CC2)C=C1
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])C4=C([H])C(=O)C(Cl)=C([H])C([H])=C4[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N1C2=C(C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
[H]C1=C(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=NC(=C([H])C(C(=O)OC([H])([H])[H])=C2C(=O)C1=O)C([H])([H])[H]
[H]OC(=O)[C@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C(=O)N([H])C2=NN=C(S2)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])[C@]([H])(OC(=O)C([H])([H])[H])N(C1=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C2=C([H])C([H])=C(N=C12)C1=NC([H])([H])C([H])([H])S1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N([C@]1([H])C([H])([H])OC([H])([H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C([H])([H])[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC(Cl)=C1C1=C([H])C([H])=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=O)C2=C(O1)C([H])=C(O[H])C(OC([H])([H])[H])=C2O[H]
[H]N=C(N([H])[H])N([H])C1=NC([H])=C([H])C2=C1C([H])=C([H])C([H])=C2OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2[N+](=C1C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N1C(SC([H])([H])C2=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C(=C2[H])C(=O)C([H])([H])[H])=NC2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]N(\N=C1/C(=O)N([H])N=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C2=C1C([H])=C(Cl)C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C1=C([H])N=C([H])C([H])=N1)N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(O1)C1=NN=C(SC([H])([H])C(=O)C2=C([H])C([H])=C([H])S2)N1C([H])([H])C([H])([H])[H]
CN[C@@H](C)C(=O)N1CCN(CC1)C1=NC(=NC(=N1)N1CCOCC1)N1C(=NC2=CC=CC=C12)C(F)F
[H]N(C1=NC([H])=NC2=C1C(OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])=NN2[H])C1=C([H])C([H])=C(OC([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C(Cl)=C1[H]
[H]N(C(=O)N(C1=NC([H])=NC(N([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])C([H])([H])N1[C@@]2([H])C([H])=C(C3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])C1=NC(=C2N1C1=NC(OC([H])([H])[H])=C([H])C([H])=C1N=C2C([H])([H])[H])C(F)(F)F
[H]OC1=C([H])C(O[H])=C2C(=O)C(O[H])=C(OC2=C1C(C([H])=C([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NC(=NC([H])=C1F)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]2([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C2([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N([H])C([H])([H])C1=C(N=C(O1)C1=C2C([H])=C([H])C(=NC2=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(\C(N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C(\C#N)C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1N([H])C([H])=C2Cl
[H]N([H])C(=O)C1=C(N([H])[H])C([H])=C(S1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])[C@]2([H])C([H])([H])[C@]3([H])O[C@@]2([H])C([H])=C3[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N1C(=O)C2=C([H])C([H])=C([H])C(N3C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])=C2C1=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])S1
[H]N(C(=O)[C@]([H])(SC1=NN=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=NC([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=NC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]1([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(C2=C([H])C([H])=C([H])O2)=C(S1)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])S1
CCNCC1=CC=C2N=C(C)C3=NN=C(N3C2=C1)C1=CC=CC=C1Cl
[H]N(C(=O)N1C(=O)C([H])([H])[C@@]1([H])OC([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)[C@@]2([H])N([H])C(=O)N([H])C(=O)C2([H])[H])C([H])=C1[H]
COC1=CC=C(C=C1OC)C1=C(O)C(=O)C2=C(O1)C=C(O)C=C2
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])[C@@]([H])(OS([O-])(=O)=O)C([H])=C([H])[C@@]4([H])[C@@]([H])(C2([H])[H])[N@@+]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@]314
[H]ON(C(=O)C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=NC(C2=C([H])C([H])=C(O2)C([H])([H])[H])=C(C(=N1)C(=O)N([H])C([H])([H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=NO[C@]2(C([H])([H])N(C(=O)OC([H])([H])C3=C([H])N=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])N([H])C3=NC([H])=C([H])N3[H])C2([H])[H])C1([H])[H]
[H]N1C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C2=C1[C@]1([H])N(C([H])([H])C2([H])[H])C([H])([H])[C@@]2([H])C([H])([H])[C@@]([H])(OC(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])[C@]([H])(OC([H])([H])[H])[C@@]([H])(C(=O)OC([H])([H])[H])[C@@]2([H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC1=NC(=NN1C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O\C(OC([H])([H])C([H])([H])[H])=C1\C(=NC(=C(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]1([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])OC([H])([H])C([H])([H])N1C(=NC(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(SC([H])=C1[H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(S1)S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C(\[H])=C(/[H])C1=C(C([H])=C(N=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C([H])=C3[H])C(=O)N([H])C1=O)C([H])([H])C([H])([H])C(=O)N([H])[H]
[H]C1=NN=NN1C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C2(C([H])([H])C2([H])[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C([H])=C([H])N([H])C1=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(N2C(Cl)=C(Cl)C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C1=C([H])C([H])=NC([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C3=C(C([H])=NN3C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])[C@]12C([H])([H])[H]
[H]N([H])C([H])([H])C1([H])C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=S)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
CN1N=C(CC(=O)NC2=CC=C(C#N)C(=C2)C(F)(F)F)C2=CC=CC=C2C1=O
[H]C1=NSC(=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])\N=C2/C(=O)N([H])C3=C([H])C([H])=C4N([H])N=NC4=C23)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C1=NC(=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])C1=C([H])C([H])=C(C2=C([H])N=C([H])O2)C(OC([H])([H])[H])=C1[H]
[H]C1=NC2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C(=N1)N1C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C([H])=C3N=C(C([H])=C([H])C3=C2[H])C([H])([H])[H])C1([H])[H]
[H]N1N(C(=O)\C(=C(/[H])C2=C([H])C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)=C2[H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C(C2=C(N=C([H])N=C12)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]SC([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N(C1=O)C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
COC1=CC=C2N(C=C(CC(=O)NS(=O)(=O)C3=CC=C(F)C=C3)C2=C1)C(=O)C1=CC=C(Cl)C=C1
[H]N1C(=NC2=C([H])N=C3C([H])=C(Br)C([H])=C([H])C3=C12)C1=C(Br)C([H])=C([H])C([H])=C1[H]
COC1=CC2=C(CN(C[C@]3(NC(=O)NC3=O)C#CC3=CC=C(CC4(C)NC(=O)NC4=O)C=C3)C2=O)C=C1
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1=NC(=NC(=C1[H])C([H])([H])[H])N1C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]C1=C([H])C(=C([H])S1)C1=C([H])C2=C(C([H])=C(C([H])=C2N=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC2=C([H])C(C#CC([H])([H])N3C([H])([H])C([H])([H])C([H])(C([H])([H])C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])C3([H])[H])=C([H])N([H])C2=N1
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C(=O)N([H])[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C2=C1C1=C(N(C(=N1)N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C(=O)N2C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)N(C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N(C(=O)OC([H])([H])C4([H])C([H])([H])C4([H])[H])[C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C(=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=[N+]([O-])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(=NN1C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])[H])C1(C2=C([H])C([H])=C(C([H])=C2[H])N2C(=O)C3=C(C(=NN3C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
FC(F)(F)C1=CC(OC2=NC=CC=C2NC(=O)NCC2=CC=CC=C2)=CC=C1
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC2=NN(C(SC([H])([H])[H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]OC(=O)C1=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])C2=NN([H])N=N2)C([H])=C(N=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C(OC([H])([H])[H])=C(N([H])C3=NN4C(=C([H])C([H])=C4C4=C([H])C([H])=C([H])C([H])=C4OC([H])([H])[H])C([H])=N3)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC([H])=NC2=C1C([H])=C(O2)C1=C([H])C([H])=C([H])N=C1[H]
[H]N1C(=C(C#N)[C@](C2=C([H])C([H])=C(F)C([H])=C2[H])(C(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C3=NC4=C([H])C(=C([H])C([H])=C4C([H])=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(=O)C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C1([H])[H])[N+]([O-])=O
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C(=C([H])N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]([H])(C1([H])[H])C([H])([H])[C@@]([H])(O[H])[C@]1([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])([C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OS(=O)(=O)O[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]21[H]
[H]O[C@@](C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(N([H])[H])=C2[H])C([H])([H])C1([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C(F)(F)C1([H])[H]
[H]N(C(=O)C1=C([H])N=C([H])C([H])=N1)[C@]1([H])C([H])([H])N(C(=O)C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C1([H])[H]
[H]C1=C(ON=C1C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=NC2=C([H])C([H])=C(OC(=O)C([H])([H])[N+]3=C(C([H])=C(C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C2S1
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=NN=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@@]1([H])P(=O)(OC1=C([H])C([H])=C([H])C([H])=C1[H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C2OC([H])([H])C([H])([H])C2=C([H])C(Cl)=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]C1=C([H])N(N=N1)C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])N=C(C([H])=C2[H])C([H])([H])OC([H])([H])[H])C1([H])[H]
[H]N(C(=O)N1C([H])=C(C(=O)[C@@]2([H])N([H])[C@]([H])(SC2([H])[H])C2=C([H])C([H])=C([H])N=C2[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C3=NOC(=N3)C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(F)=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([C@@]([H])(C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C(=O)N([H])S1(=O)=O)S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=NC(=NC([H])=C1C1=NN=C(O1)C1([H])C([H])([H])C1([H])[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N1C2=C(C([H])=C(Br)C([H])=C2[H])C2=C1C(=S)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]O[C@]1([H])C2=C(C(C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)=C(N=C2C([H])([H])[C@]2(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])N1C([H])=NC2=C1N=C(N=C2N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C2C([H])=C(Br)C([H])=C([H])C2=NC1=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=[N+](C([H])([H])[H])C(C([H])=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C2=C(N=C(SC3=C([H])C([H])=C([H])C(Cl)=C3[H])C([H])=C2[H])C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]C1=C2C(=C([H])C(OC([H])([H])[H])=C1[H])N(C(=C2C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C(F)=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(SC2=C([H])C([H])=C(Cl)C([H])=C2[H])=NN(C1=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])N1N=NC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC1=NN=C(N1C([H])([H])C1=C([H])C([H])=C([H])O1)C1=C(OC([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)S[C@@]([H])(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC2=C(C([H])=C(C([H])=C2[H])C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(SC([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])N([H])\N=C(/[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N=C(N([H])[H])N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]SC([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]