[H]N1C([H])=C([H])C2=C1N=C([H])N=C2N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[C@]3([H])C([H])([H])[C@]3(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])[H]
[H]C1=C(C([H])=C(C(=C1[H])N(C1=NC(=NC(=N1)C([H])([H])[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(F)(F)F)N(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]N(C(=O)N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]12C([H])([H])C([H])([H])[C@@]([H])(C(=C([H])[H])C([H])([H])[H])[C@]1([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)N1C([H])=NC2=C1N=C(OC([H])([H])[H])N=C2C1=C([H])C([H])=C([H])O1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N=C(N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=N\C([H])([H])C([H])([H])[H])\N([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C3=C([H])C(F)=C([H])C([H])=C3N2C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC3=C(S2)C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]OC1=C2N([H])C(F)=C(C2=NC([H])=N1)[C@]1([H])N([H])[C@]([H])(C([H])([H])O[H])[C@]([H])(O[H])[C@@]1([H])O[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C2=NC(N([H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])=C([H])C([H])=N2)C(O[H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SN=N1)C([H])([H])C1=C([H])C([H])=C2C([H])=C(Br)C(=C([H])C2=C1[H])C(F)(F)S(=O)(=O)N([H])[H]
[H]C#CC([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C2=C([H])C(OC([H])([H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])=C([H])C([H])=C2N1C([H])([H])[H]
ONC(=O)CCCCCNC(=O)NC(=O)C1=CC(=C(C=C1)N1CCOCC1)N(O)=O
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N(C(=O)N(C1=O)[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)C([H])([H])[C@](C2=O)(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON1C([H])=C([H])C([H])=C(N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])S(=O)(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1=O
CC1=C(CCOCCO)C=C(N1C1=CC=C(F)C=C1)C1=CC=C(C=C1)S(C)(=O)=O
[H]O[C@@]1([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C2([H])[H])[C@](O[H])(C2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[C@@]1([H])N([H])[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(N=C2Cl)C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=NC(Cl)=NC(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C1=C2C([H])=C(N([H])C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])=C([H])C2=NC(=C1[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])S2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC(=NC(=C2[H])C(F)(F)F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N1C2=C(OC([H])([H])C1([H])[H])C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(C1=C([H])C(Cl)=C(F)C([H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=N3)C([H])=C12
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C3OC([H])([H])C([H])([H])C3=C12
[H]N(C(=C1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])OC1=C(C([H])=C(Cl)C([H])=C1C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C3=C([H])C([H])=C(F)C([H])=C3[H])[C@]2([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]1([H])N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C(OC([H])([H])[H])C([H])=C([H])C2=C([H])C3=[N+](C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C31)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])N(C([H])([H])[H])S(=O)(=O)C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C2=C3C(=O)N(C(=O)C3=C([H])C([H])=C2[H])[C@@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C2O[C@@]([H])(N([H])C2=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C2[H]
[H]C1=C(C2=NSN=C2OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=NSN=C2C2=C([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC2=NC([H])=NC(N([H])C3=C([H])C([H])=C([H])C(Br)=C3[H])=C2C([H])=C1[H]
[H]N(\N=C(/[H])\C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[N+]([O-])=O)C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])[C@@]2([H])C([H])=C([H])C([H])=C([H])[C@@]12[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC(=NC(=N1)N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
CN1N=C(CC(=O)NC2=CC=CC(=C2)C(F)(F)F)C2=CC=CC=C2C1=O
[H]C([H])=C(C([H])([H])[H])C([H])([H])N([H])C1=NC([H])=NC2=C1C1=C(S2)C(=O)N(C([H])=N1)C1=C([H])C([H])=C2OC([H])([H])C([H])([H])OC2=C1[H]
[H]N(C(=O)C1=NN(C([H])=N1)C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=NN(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C([H])=C([H])C([H])=C([H])C2=NC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N2N=C(OC([H])([H])[H])C(N(C([H])([H])C([H])([H])OC([H])([H])[H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2S1)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C1=C([H])C2=C(N=C([H])C([H])=N2)C([H])=C1[H])[C@]([H])(C1=NC2=C(SC([H])=C2[H])C(=O)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C3C([H])=C(C([H])=C([H])C3=C2[H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC(=C([H])S2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N([H])C1=C(C(=O)N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N=C2N1C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]OC([H])([H])C1=C([H])N(N=C1C(F)(F)F)C([H])([H])C1=C([H])C2=C(C([H])=C1[H])[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C2([H])[H]
[H]\C(=C1\S\C(=N/C([H])([H])C([H])([H])OC([H])([H])[H])N(C1=O)C([H])([H])[H])C1=C(N(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(\C([H])=C2/C(=O)/C(=C(\[H])C3=C([H])C([H])=C(C([H])=C3[H])C(=N[H])N([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(\N=C1/C(=O)N([H])N=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@]1(C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])C1=C([H])N(C2=C1C(F)=C([H])C([H])=C2[H])C([H])([H])C(=O)N(OC([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=NC([H])=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CNC1=NC(NC2=C(Cl)N(C)N=C2)=NC=C1C(F)(F)F
[H]N1C2=C(N=C1[C@]1(C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C(C#N)=C([H])C([H])=C3[H])C([H])([H])[C@]11C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])=C(F)C(=C2[H])C(F)(F)F
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H]
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[H]N1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])C(OC([H])([H])[H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]\C(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])=C1\C([H])([H])N2[C@]3([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@@]1([H])C3([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C1C([H])=C([H])C(Cl)=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C(=O)OC2=C([H])C(OC([H])([H])C3=C([H])C(F)=C([H])C([H])=C3[H])=C([H])C([H])=C12
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(N([H])C2=NC3=C(C#N)C([H])=NN3C(=N2)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1[H]
[H]OC1=NC(=NC2=C1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H])N([H])[H]
[H]N([H])C1=N[C@@](C2=C([H])C(=C([H])C([H])=C2F)C([H])([H])C(=O)C2=C([H])N3C([H])=C(N=C3C([H])=N2)C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])S1
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N([H])C2=NC([H])=C(C([H])=C12)C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C2=C(C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=N[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C2=C(F)C([H])=C([H])C([H])=C12
[H]N(C1=C([H])C2=C(C([H])=C1[H])C([H])=C([H])C1=C(C([H])=C(C([H])=N1)C1=C([H])N(N=C1[H])C([H])([H])[H])C2=O)S(=O)(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C1(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]SC([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N(C1=O)[C@@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
CCCC1=C(NC2=NC=NC3=C2N=CN3C2O[C@H](CO)[C@@H](O)[C@H]2O)C=CC=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C(=O)C1=C(N=C2N1C([H])([H])C([H])([H])N2C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)[C@@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])OC([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(SC([H])([H])[C@]([H])(O[H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1C([H])([H])[H]
[H]O[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])S1)[C@@]([H])(O[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]N(\C(=N\C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C1=NC(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1Cl)S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N(C2=C(C(N([H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]OC(=O)[C@@]([H])(OC1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])[C@]1(N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(SC([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])OC2=C([H])C3=C(C(=O)[C@@]([H])(C3([H])[H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(=C2C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N1C(=O)N([H])[C@@]([H])(C1=O)C1=C([H])C(Cl)=C([H])C([H])=C1S(=O)(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N1C([H])=C(N=C(N([H])C([H])([H])C2=NON=C2C([H])([H])[H])C1=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])[N@+]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C2O[C@]([H])(N([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)O[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C2N(C(SC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C(=C3[H])[N+]([O-])=O)=NC2=C([H])C(N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1N=NN=C1C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])N([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(Br)N=C1OC([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2N(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C3C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C4O[C@@]([H])(C4=C([H])C([H])=C([H])C([H])=C4[H])C3=C2C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C2([H])[H]
[H]C#CC([H])([H])N1C([H])([H])C2=C(N([H])[H])C3=C([H])C(C#N)=C(Cl)N=C3N=C2C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)N1C([H])([H])C([H])([H])N(C(=O)N2N=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(F)C([H])=C1F)C1=C([H])C(C2=C(Br)C([H])=NN2C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C(OC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C(=O)N(C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C(\[H])=C(/[H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C(=C1[H])C([O-])=O)C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]O[C@@]1(OC(=O)C(=C1C([H])([H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(C(=NN2C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(S[C@]([H])(C1=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)C1=NC(=C([H])N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(C#N)C2=C([H])C(OC([H])([H])[H])=NC(N([H])[H])=C12
CN1C(N)=N[C@](C1=O)(C1=CC(C)=C(OC(F)F)C=C1)C1=CC(C#CC2CC2)=C(F)C=C1
[H]N(C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])[H])=C(C([H])=N1)C(F)(F)F)C1=C([H])C2=C(N([H])C(=O)C2([H])[H])C([H])=C1[H]
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[H]N([C@]1([H])C([H])([H])C([H])([H])[C@](C(=O)N2C([H])([H])[C@@]3([H])N(C(=O)C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@]2([H])C3([H])[H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])F
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[H]N([H])C1=C([H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
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[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=O)N2C([H])([H])[C@]([H])(O[C@@]([H])(C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C(F)C([H])=C3[H])[C@]2([H])C1([H])[H]
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[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C([H])([H])[H])C1=NC2=C(N=C(N2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C(C([H])=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C3=C(C4=C(N3[H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@@]12[H]
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[H]N1C(=O)C([H])([H])OC2=C([H])C([H])=C(C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])C1=NN=NN1C1=C(Cl)C(=C([H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C(=O)O[H]
[H]N([H])C(=O)N([H])C1=C(C([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])O[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(C(=O)O[H])C([H])([H])[P@@](=O)(O[H])C([H])([H])C1=C(F)C(F)=C(F)C(F)=C1F
[H]N([H])C(=O)C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])N(N=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(OC(=N2)C2=C(N=C([H])C(=C2[H])C2=C([H])N(N=C2[H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])N([H])[H])C([H])=C1C([H])([H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])[C@]1([H])C(=O)N(C(=O)N([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])[C@@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])\C(=N/N([H])C(=O)N([H])[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@@](=O)(O[H])OP(=O)(O[H])O[H])[C@@]1([H])O[H])N1C([H])=C([H])\C(=N\OC([H])([H])C([H])([H])[H])N([H])C1=O
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N2C(=O)N([H])C(=C(C(=O)OC([H])([H])[H])[C@@]2([H])C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(N=C(N(C1=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN=NN1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C1=C([H])C(=NC(=N1)N1C([H])=NC(=C1[H])C1=C(OC(F)(F)F)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@]1([H])N(C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])OC([H])([H])C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])=C(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
OC(=O)CN1CCN(CC1)C1=CC2=C(OC(=N2)C2=CC=C(C3=CC=CC=C3)C(=C2)C(F)(F)F)C=C1
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[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C1OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1C2=O)C([H])([H])[H]
[H]SC([H])([H])[C@@]([H])(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S([O-])(=O)=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C([H])C2=C(N([H])C(=O)C([H])=C2C(F)(F)F)C([H])=C1[H])C([H])([H])C(F)(F)C(F)(F)F
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C#N)[C@@]([H])(C2([H])[H])[C@@]1([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2N(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)[C@@]([H])(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(C(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(C(=C(SC3=C([H])C([H])=C([H])C([H])=C3[H])N2[H])C([H])([H])C([H])([H])[H])C(=N1)N([H])[H]
[H]OC([H])([H])C([H])([H])C1(N([H])C([H])([H])C(=O)N2[C@]([H])(C#N)C([H])([H])C([H])([H])[C@]2([H])C#N)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])C(=NS3)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C(=O)N([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@]([H])(N([H])[H])C([H])([H])SC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H]
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[H]C1=NC([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C2=C(C3=C(S2)N2C(=NN=C2[C@]([H])(N=C3C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(\C([H])=C(/[H])C(OC([H])([H])[H])=C(C#N)C#N)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C1([H])[H])[C@@]([H])(C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]C1=C([H])C(=O)N(C1=O)C1=C([H])C([H])=C([H])C([H])=C1Cl
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1(N([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C3C(=NC([H])=N2)N([H])C([H])=C13)C(=O)OC([H])([H])C([H])([H])[H]
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[H]C1=NC(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(P([O-])([O-])=O)S([O-])(=O)=O
[H]OC1=C(OC([H])([H])C([H])=C=C([H])[H])C([H])=C2C(=NC([H])=NC2=C1[H])N([H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
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[H]C1=C(SC2=C1N=C([H])N(C2=O)[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@]2([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C2=C(N=N1)C1=C(C([H])=C([H])C([H])=C1[H])C2=O
[H]N1C(=NC2=C1C([H])=C1OC(F)(F)OC1=C2[H])N1C([H])([H])C([H])([H])C2(OC(=O)C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(\C(=N\C(=O)C1=C([H])N=C([H])C([H])=N1)N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(OC(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@@](C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
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[H]N(C(=O)C(\[H])=C1\C2=C(C([H])=C([H])C([H])=C2[H])N(C(=O)C2=C(Cl)C([H])=C(C([H])=C2[H])N2N=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(Cl)N(C2=NC(=C(N12)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C1([H])[H])C(F)(F)F)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H][C@@]12CCC3C4CCC(C(C)CCC(O)=O)[C@@]4(C)C(O)CC3[C@]1(C)CCC(O)C2
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[H]O[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C(=O)N([H])C([H])([H])[C@@]2([H])C([H])([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
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[H]OC1=C([H])C([H])=C2OC(\C([H])=C(/[H])C3=C([H])C([H])=C(C([H])=C3[H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C2=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])SC2=C([H])C(O[H])=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])O[H])C([H])([H])C2([H])[H])C([H])=C1[H]
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OC1=CC=C(C(=O)\C=C\C=C\C2=CC=C(Cl)C=C2)C(O)=C1
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[H]N([H])C1=NC2=C(OC3=C([H])C([H])=C(Cl)C([H])=C23)C(=N1)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1(C2=C(F)C([H])=C([H])C([H])=N2)C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])S1
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])S[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C2O[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])OC2=C1[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1F
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[H]N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(N=C3C([H])=C([H])C([H])=C([H])C3=C2C(=O)N([H])[C@@]([H])(C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
CN1CCN(CC1)C1=CC=C(N\C=C2/C(=O)NC(=O)C3=CC=C(C=C23)N(O)=O)C=C1
[H]O\N=C1\OC(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=S)S\C(=C(\[H])C2=C([H])C3=C(OC([H])([H])C(=O)N3C([H])([H])C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])=C2[H])C1=O
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N2C([H])([H])C#CC1=C([H])C2=C(C([H])=C1[H])N1C(=NN=C1C(F)(F)F)C([H])([H])N=C2C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C(OC([H])([H])C(=O)O[H])C(Br)=C(S1)C1=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C2C([H])=C([H])C(=C([H])C2=N1)N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C(C([H])=C(O[H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C1=C(C#N)C(=NC2=C([H])C([H])=C(Cl)C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
COC1=C(C=C(C=C1)C1=NNC(=N1)C1=CC=NC(C)=C1)N(O)=O
[H]N1C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C3N=C(N(C(=O)C3=C2[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S1(=O)=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(SC2=C([H])C([H])=C(C3=NSN=C23)S(=O)(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=NN=C2C([H])=C([H])C(SC3=C([H])C([H])=C(F)C([H])=C3F)=C([H])N12
[H]N1C(=NC2=C(C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])C2=NN(C(=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])N=C([H])C(=C1[H])C1=C([H])C([H])=C2C([H])=NC(C([H])=C([H])[H])=C([H])C2=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C([H])=C(Cl)C(=C2[H])C([H])([H])C2=NN=C(S2)C([H])([H])C(F)(F)F)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])C1=NC(=C([H])C(=N1)C(=O)N([H])C([H])([H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1[H])C1=NN(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N=C(N1C([H])([H])[H])C([H])([H])C([H])([H])C1=NC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C2=C([H])C(=NN12)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C(I)=C1OC([H])([H])[H])C([H])([H])C(=O)OC([H])([H])C1=C([H])[C@@]2([H])[C@@]3([H])O[C@@]4(O[C@@]3(C(=C([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]2(O4)[C@]2([H])C([H])=C(C(=O)[C@@]2(O[H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
FC1=C(C=C(CC2=NNC(=O)C3=C2CCCC3)C=C1)C(=O)N1CCC2=C3C1CNC(=O)C3=CC=C2
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])S1)[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@](C2=C([H])C(F)=C([H])C([H])=C2F)(C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([C@]1([H])C([H])([H])C([H])([H])[C@](C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(\C([H])=C(/[H])C([H])([H])[H])=C([H])N=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C2OC([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([C@@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C3=C([H])C([H])=C(S3)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])OC([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])N=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C(F)(F)F)C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N(N(C([H])([H])[H])C([H])([H])[H])C(=O)N2[H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2C(Br)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC(=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])=C1/C([H])([H])[N@+]2([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])N([H])[C@@]([H])(C([H])([H])[H])C1([H])[H])C1=NC([H])=C(SC([H])([H])C2=NC([H])=C(O2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S1
[H]N(C1=C2C([H])=C([H])C(OC([H])([H])[H])=C([H])C2=NC([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=CC=C(\C=C\C2=C(/C=C/C(=O)NCC#C)C(OC)=CC(OC)=C2)C=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])=C1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C([H])([H])N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[H]
[H]OC([H])([H])C([H])(C([H])([H])O[H])C([H])([H])N1C([H])=C(C2=C(N=C([H])N=C12)N([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=NC2=C(S1)C([H])=C([H])C(=C2[H])S(=O)(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC(=O)[C@@]([H])(OC1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])[C@]1(N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1(C(=O)O[C@@]2([H])C([H])([H])[N@+]3(C([H])([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C3([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1N(C(=O)\C(=C(\[H])C2=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
NC1=NC(=CC=N1)N1C=CC2=C1C=C(Br)C=C2
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])C(=O)C1=C([H])C2=C(S1)C([H])=NC([H])=C2SC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])[C@]([H])(OC(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])N([H])[C@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C(Cl)=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C2=C(SC([H])=C2[H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)N([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C(=O)C1=C(N([H])N=C21)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=NN1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C2N(C([H])([H])[H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3(C2=C1[H])C([H])([H])[H])C1=C([H])C(Cl)=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(F)=C([H])C(=C1[H])N1C(=O)C(=C(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])N(N=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H][C@]12CC[C@]([H])(C[C@H](C1)OC1=CC=CC(=C1)C(N)=O)N2[C@H](C)C1=CC=C(Cl)N=C1
[H]N(C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C1(N2C([H])([H])C([H])([H])N(C(=O)[C@@]3([H])C([H])([H])N(C([H])([H])[C@]3([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])[C@]([H])(C1=C([H])N=C(I)C([H])=C1[H])C2([H])[H]
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[H]N1C(=O)C2=C(C1=O)C1=C(C3=C2C2=C(N3[H])C([H])=C(C([H])=C2[H])C(F)(F)F)C(=C([H])C2=C1N(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(N2C([H])=C(C([H])=C([H])C2=N1)C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1F)C(=O)C1=C(F)C([H])=C([H])C([H])=C1F
[H]OC(=O)C1=C([H])C([H])=C([H])C(\C([H])=C(/[H])C2=C(Cl)C([H])=C(OC([H])([H])C3=C(ON=C3C3=C(C([H])=C([H])C([H])=C3F)C(F)(F)F)C([H])([H])C([H])([H])[H])C([H])=C2[H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@@]([H])(C2=C(C([H])=C([H])C(Cl)=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C1([H])[H]
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[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C(Cl)C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C(N=C([H])S1)C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C2=C([H])C(=O)C([H])([H])C([H])([H])[C@@]2(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C2=C1OC([H])([H])O2)C(\C([O-])=O)=C(\C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])S(=O)(=O)N([H])[H]
[H]C1=C([H])C([H])=C2N=C(SC2=C1[H])[C@]([H])(C#N)C1=C(Cl)C(=O)N(N=C1[N+]([O-])=O)C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1(OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)C([H])([H])N1C(SC([H])([H])C2=C(F)C(F)=C(F)C([H])=C2[H])=NN=C1C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]C1=C2C(C(=O)[C@]([H])(C([H])([H])[H])C2([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1OC([H])([H])[H]
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O[C@@H]1COC[C@H]1NC1=C(C=NC(NC2=CC(Cl)=CC(Cl)=C2)=N1)C1=CC=C(F)C=C1
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[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C([H])C(=O)N(C(=O)N2C([H])([H])C2=C(Br)C([H])=C([H])C(F)=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(\N=C(\C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=NC2=C(O1)C([H])=C(Cl)C([H])=C2[H]
[H]N(C(=O)C1(N([H])C(=O)C(F)(F)F)C([H])([H])C1([H])[H])[C@@]([H])(C1=C(F)C([H])=C(C([H])=C1[H])N1N=C(Cl)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(N([H])C(=O)N([H])C2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])[C@]([H])(OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(O1)[C@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])C(=C([H])C(=C1N(C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(\N=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])=C1[H]
[H]S\C(=N/N([H])C1=C([H])C([H])=C(C([H])=C1[N+]([O-])=O)S(=O)(=O)N1C([H])=C([H])C([H])=C1C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])N([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(C([H])=NC2=C(C([H])=NN12)C1=C([H])C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])SC1=NC2=C(N=N1)C1=C(C([H])=C([H])C([H])=C1[H])N(C(=O)C([H])([H])[H])[C@@]([H])(O2)C1=C([H])C(OC([H])([H])C([H])([H])[H])=C(OC(=O)C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C(=N1)C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C2N=C(OC2=C1[H])C([H])=C1[C@@]2([H])C([H])([H])[C@@]3([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C2([H])[H])C3([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C(N([H])C(=O)C([H])=C2[H])C1=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C(Br)=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(Cl)C([H])=C(C(OC([H])([H])C(=O)OC([H])([H])[H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])SC([H])=N1
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])(O[C@@]1([H])C([H])([H])[C@@]3([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C3([H])[H])[C@]1([H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C21
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)OC1=C([H])C([H])=C(\C([H])=C(/[H])[N+]([O-])=O)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C(Cl)C([H])=C([H])C(Cl)=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)N([H])C1=NN=C(S1)S(=O)(=O)N([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])C1=NN=C(S1)S(=O)(=O)N([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C(Cl)=C2C(=O)O1
[H]N=C(N([H])[H])C1=C([H])C(=C(SC([H])([H])[H])S1)C1=C([H])SC(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2(C3=C1C([H])=C(C([H])=C3[H])C1=NC3=C(N=NN3C([H])([H])C3=C([H])C4=C([H])C([H])=C([H])N=C4C([H])=C3[H])N=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H]
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C(N(N(C1=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2N=C([H])C([H])=NC2=C1[H]
[H]N1N=C(C([H])=C1C1=C([H])C([H])=C([H])S1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C(=O)OC([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C(N([H])C2=C([H])C(C#N)=C([H])C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2N=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
OC1=C(SC2=NC=NN2)C=C(NS(=O)(=O)C2=CC=C3C=CC=CC3=C2)C2=CC=CC=C12
[H]N(C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C2=N[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C([H])([H])C([H])([H])S2)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N1C(=O)C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(=N[H])N([H])[H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
COC1=CC2=C(C=CN=C2C=C1)C1CN(C2CCN(CCCC3=CC=CC=C3)CC2)C(=O)O1
[H]N(C(=O)C([H])([H])C1=C(Cl)C([H])=C(OC(=O)C([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C(=C([H])C([H])=C2C(OC2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C1C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C([H])=C(C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])[C@@]3([H])C([H])([H])C4=C(N([H])N=C4[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])N1C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NN=C(O1)SC([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=NC([H])=C([H])N=C2N1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N([H])C1=NC(=C([H])C(=N1)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(I)=C(C([H])=C1OC([H])([H])[H])C(=O)OC([H])([H])C1=C([H])[C@@]2([H])[C@@]3([H])OC([H])([H])O[C@@]3(C(=C([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]2(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]2([H])C([H])=C(C(=O)[C@@]2(O[H])C1([H])[H])C([H])([H])[H]
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[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])[C@]2([H])C([H])([H])[C@]1([H])C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])O1)C2([H])[H]
COC(=O)C1=CC=CC=C1CN1N=CC(Cl)=C(OC2=CC=C(OC)C=C2)C1=O
[H]N(C(=O)C([H])([H])C(N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]O[C@@]1([H])C([H])([H])C(=O)N2C([H])([H])[C@]([H])(O[C@@]([H])(C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C(F)C([H])=C3[H])[C@]12[H]
[H]N(C(=O)N([H])C1=C(SC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])[H])C1=NN=C(S1)C1([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=NN(C1=O)[C@]([H])(C([H])([H])OC([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C(=C(OC([H])([H])[H])N=C1C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C(=C2C2=C1C(=NC([H])=N2)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])([H])C1([H])[H])[N+]([O-])=O
[H]C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C(N2C3=C(N(C(=N3)C([H])([H])C([H])([H])[H])C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C2=O)C([H])([H])[H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C([H])S1)C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC2=C3C(F)=C([H])N(C3=NC([H])=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])SC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C(C([H])=C([H])C(=C2[H])C(F)(F)F)[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C([H])C(=NC2=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C2(C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]OC([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(N=C1N([H])[H])C([H])([H])N1C(=C([H])C([H])=C1C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C(OC([H])([H])[H])C(=NC2=C([H])C([H])=C(F)C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1(N2C(=N[C@@]3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]23[H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=C(C([H])=N1)[C@@]1([H])SC([H])([H])C(=O)N1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])C(=C1[H])C1=NN([H])C(=S)N1C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(C#N)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1(C#N)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C(N=C=S)C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(N2N=C([H])C(=C2[H])C2=C([H])C(=NO2)C2=C([H])C([H])=C([H])C(F)=C2Cl)C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=C(C([H])=C2C#N)C(=O)OC([H])([H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=NC(=N1)C1=C(C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[O-]C(=O)C(F)(F)F.COC1=CC2=C(C=C1OC)C=[N+]1CCC3=CC(OC)=C(O)C=C3C1=C2
[H]C1=C(C2=NC(=NO2)C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1
[H]C1=C2N(C(=N1)C1=C([H])C([H])=C([H])C(Cl)=C1C([H])([H])C([H])([H])C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(\C(=N/C#N)N([H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N1C([H])([H])C2=C([H])C(Br)=C([H])C([H])=C2C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=NC2=C(SC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)N=C([H])N=C2N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C2C(Cl)=C(OC([H])([H])[H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(O[H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]C1=C(SC2=C1C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C(Cl)C([H])=C2C([H])=C1[H]
[H]O[C@]1(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N1C([H])([H])C([H])([H])[C@]2(C(=O)N([H])C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=NN=C(SC2=NC([H])=C(S2)[N+]([O-])=O)N1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
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