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[H]N(C(=O)C([H])([H])N1C2=C(C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(Cl)C([H])=NC([H])=C1Cl)C([H])([H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@]([H])(OC1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])[H]
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[H]\C(=C(\[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(\C([H])=C(/[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H])C(=O)OC([H])([H])[H]
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[H]ON1C(=O)[C@]([H])(N([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
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[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(C1=C([H])C(=C([H])C(N([H])C(=O)[C@]2([H])C([H])([H])C3=C(C([H])=C([H])C(OC4=C5C(=NC([H])=C4[H])N([H])C(=O)C([H])([H])C5([H])[H])=C3[H])C([H])([H])C2([H])[H])=C1[H])C(F)(F)F)(C([H])([H])[H])C([H])([H])[H]
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[H]N(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(\[H])=C(/[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N=C(N([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C2C(N=C([H])N=C2N2C([H])([H])C([H])([H])N(C(=O)N([H])C3=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])=C1[H]
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[H]N=C(N([H])[H])C1=C([H])C([H])=C2C([H])=C([H])C(=C([H])C2=C1[H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
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[H]OC(=O)C([H])([H])[C@]1(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]1([H])C3([H])[H])C2([H])[H]
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[H]C1=C2N=C([H])C([H])=C([H])N2N=C1C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])C1([H])[H]
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[H]N([H])C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])=C1[H]
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[H]OC(=O)C([H])([H])N1N=C(C(=C1C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])[H]
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[H]N(\N=C(/[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=NN([H])C(=S)S1
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[H]N(C(=O)C1=C([H])C(I)=C(N=[N+]=[N-])C([H])=C1[H])C([H])([H])C1=NN(N=N1)C(=O)N(C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])\C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=C2C(=N1)N(C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C2([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
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CCNC(=O)C1=CC=C2N=C(C)C3=NN=C(N3C2=C1)C1=CC=CC=C1OC
[H]N1C2=C(C([H])=C1S(=O)(=O)C1=NN([H])C(=O)C([H])=C1[H])C([H])=C(Cl)C([H])=C2[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])N(C2=NC([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C#N)C1=C(Cl)C([H])=C([H])N=C1N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C1=NOC(=N1)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])N([H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(S[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C([H])=C(I)C([H])=C([H])C2=N1)C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=NC([H])=C(N=C2C([H])=C1[H])N1C([H])([H])C([H])([H])C2(C(=O)N(C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C(F)(F)F)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)N([H])C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\[H])C3=C([H])C(=C([H])N3[H])C(=O)N([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C2=C1[H]
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[H]N(C(=O)C1=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C3=NSN=C23)C([H])=C(Cl)C([H])=C1[H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C(=O)C1=C2N(C([H])=C([H])C([H])=C2OC([H])([H])C(=O)OC([H])([H])[H])C(=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C3=C(C(Cl)=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2=O)C([H])([H])C1([H])[H]
[H]O[C@]1(C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])=C([H])[H])C2([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C2N([H])[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C(N2N=C1[H])(C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)N=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N1C2=C(C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C2=O)S(=O)(=O)C([H])([H])C1([H])[H]
[H]N(C(=O)O[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C1([H])[H])C([H])([H])[C@@](N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)(C3([H])[H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H])C1=NN=C(S1)C(F)(F)F
[H]N(C(=O)N([H])C([H])([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C([H])C([H])=C(C([H])=C12)S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N(C([H])=N1)C1=NC(N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N(N=C1C([H])([H])[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
CN1C(N)=NC2(CC(C)(C)SC3=C2C=C(C=C3)C2=CC(Cl)=CC(F)=C2)C1=O
[H]ON([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2OC1=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[N+]([O-])=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]1([H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N([H])C(=S)N([H])N=C1C2=C(C([H])=C([H])C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C2[H])C2=C1C([H])=C(OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])=C2[H]
[H]N(C1=NC2=C([H])C(N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2N2C([H])=NC([H])=C12)C1=C(F)C([H])=C([H])C([H])=C1Cl
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C1C1=C([H])C([H])=C([H])C([H])=C1C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)N([H])[C@]2(N(C(=O)N([H])C3=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C23)C([H])([H])[H])C1=O
[H]N(C(=O)C(\[H])=C(/[H])C1=C2N(C(=O)C([H])([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]S\C(=N/N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])N([H])[H]
[H]C1=NN(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=N1)C(=O)N1C([H])([H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@](C([H])([H])[H])(C([H])([H])OC2=NC([H])=C(Cl)C([H])=C2[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])O[C@]12\C(=N/OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(Cl)C([H])=C2[H])C1=C([H])C([H])=NC([H])=N1
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N3C([H])([H])C([H])([H])N(C([H])([H])C4=NOC(=C4[H])C([H])([H])[H])C([H])([H])C3([H])[H])C(Cl)=C([H])N=C2N1[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C(F)C([H])=C1Cl
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C(=N\OC([H])([H])[H])\[C@]([H])(OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])C(=O)N1C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(SC([H])([H])C(=O)[C@@]2([H])C([H])([H])N(C(=O)C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]12[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C(C([H])=C([H])C(=C2[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2=NC([H])=C([H])C([H])=C2[H])N(C(=O)C([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H]
[H]OC1=NC(=NN1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@@]([H])(O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)N([H])C2=C(C1=O)C(=C([H])C(=O)O2)C([H])([H])C([H])([H])C([H])([H])C([H])(F)F
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3(OC([H])([H])C([H])([H])O3)C([H])([H])C2([H])[H])C2=NN(C(=O)N12)C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])C([H])([H])[H]
[H]ON1C(=O)C2=C([H])C([H])=C([H])C([H])=C2N([H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])N=C(C([H])=C1[H])N(C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]C1=C([H])C2=C(OC([H])([H])O2)C(=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])SC2=NC(=C(S2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])=C(C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N=C([H])C([H])=N1)N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(OC2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)C1=C(N=C([H])C([H])=N1)N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(OC2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(O[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=N1)S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NC(C#N)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C([H])C(Br)=C([H])C([H])=C12)C(C([H])=C([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(N([H])C(=O)C([H])([H])SC1=NN=C(N1N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])Cl)C(=O)C([H])([H])[H]
[H]N=C(N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(=NN2C2=C(F)C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])[H])C([H])=C1[H]
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[H]N(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN2C([H])=C(C([H])=C([H])C2=N1)C1=C([H])N=C([H])C(=C1[H])S(=O)(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(F)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
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[H]N(C(=O)C([H])([H])N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C1=NC([H])=C([H])S1)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C2=C1N=C(S2)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]C1=C([H])N=C(S1)C1=NN(N=N1)C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]N([H])C1=C([H])C(=C([H])C(=N1)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C2=C(C([H])=C1[H])[C@]13C([H])([H])C([H])([H])N(C([H])([H])C([H])=C([H])[H])[C@]([H])(C2([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C(N=C2N1C(=O)C(C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])=C(N2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)C(=C([H])C2=C1C([H])=C(C([H])=C2[H])C(F)(F)F)C1=C([H])SC(=N1)C1=C([H])C([H])=NC([H])=C1[H]
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[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1(SC2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N1N=NN=C1C1=NN([H])C2=C1C([H])([H])[C@@]([H])(C1=C([H])C(F)=C([H])C(F)=C1F)C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1C#N)C1=C([H])C2=C(SC(=N2)C([H])([H])[H])C([H])=C1[H]
[H]OC1=NC2=C([H])C(Cl)=C([H])C([H])=C2C(O[H])=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])OC([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])N1N=C(C([H])=C1C([H])([H])N(C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C2=C(N=C([H])N=C2C([H])=C1OC([H])([H])[H])N([H])C1=C(F)C(Cl)=C([H])C([H])=C1[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N([H])C(=O)C2=C1C1=C([H])C([H])=C([H])C([H])=C1N2C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C2=C(C(=NN2C2=C([H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C([H])C2=C(C([H])=C1Cl)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]2([H])C1=C([H])C([H])=C([H])C2=C1OC([H])=C2[H]
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[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C(N=C(S2)C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H]
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[H]OC1=C([H])C(=C([H])C2=C([H])C(=C([H])C(O[H])=C12)S([O-])(=O)=O)S([O-])(=O)=O
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[H]N1C([H])=C(\C([H])=C2/SC3=C([H])C([H])=C([H])C([H])=C3N([H])C2=O)C2=C1C([H])=C(OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])=C2[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N([H])C1=NC2=C(N=NN2C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2F)C(=N1)C1=C([H])C([H])=C([H])O1
[H]\C(C(=O)C1=C([H])N=C([H])C([H])=C1[H])=C1/C(=O)N(C2=C([H])C([H])=C([H])C(Cl)=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2Cl)C(=O)N([H])C2=NC(=C(S2)C([H])([H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C(F)C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)C([H])([H])N1C(=O)[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])C([H])(C([H])([H])C4=C([H])C([H])=C(C([H])=C4[H])C(F)(F)F)C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1=C(F)C(N([H])C([H])([H])C(F)(F)C2=C([H])C([H])=C([H])C3=C([H])N=C([H])C([H])=C23)=C([H])C([H])=C1Cl
[H]OC(=O)C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])S(=O)(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3C([H])=C(F)C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(S1)C1=C2C(=NN1[H])C1=C([H])C(=C([H])C([H])=C1C2([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]\C(=C(\C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])ON=C3C4=C([H])C([H])=C(OC(=O)C5([H])C([H])([H])C5([H])[H])C([H])=C4OC([H])([H])[C@@]23[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])N(C1=O)C([H])([H])[H])C(=O)N(C([H])([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C(\[H])=C(\C(\[H])=C(/[H])C(=C(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])/C([H])([H])[H]
[H]OC1=NC2=C3N1C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C2[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(Cl)=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1N(C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(Cl)C([H])=C2C(OC(=O)C([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC(=O)C([H])([H])[H])C2=C1[H]
[H]N1C([H])([H])C2=C([H])C(=C([H])C([H])=C2C([H])([H])[C@]1([H])C(F)(F)F)[N+]([O-])=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(OC([H])=C(C3=C([H])C([H])=C(F)C([H])=C3[H])C(=O)C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(N([H])C(\[H])=C2/C(=O)N([H])C3=C([H])C([H])=C([H])C([H])=C23)=C1[H]
[H]S\C(=N\C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2C([H])=C(N([H])[H])C(N([H])C([H])([H])C([H])([H])[H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(F)(=O)=O)C([H])([H])C([H])([H])C([H])([H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C(N2C([H])=C([H])C([H])=C([H])C2=N1)C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])[C@@]([H])(F)C2([H])[H])C([H])([H])C1([H])[H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])SC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N1C(=O)N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[N@+]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C(OC(=O)N([H])C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C([H])([H])[H])=C([H])C([H])=C3N(C([H])([H])[H])[C@@]12[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])F)C([H])=C1[H])C([H])([H])C(\[H])=C(/[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N2N=C(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(Cl)=C2C([H])([H])[H])C(=C1[H])C(=O)N1C([H])([H])N([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]C1=C([H])C(=O)N(C1=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N2C([H])([H])C3=C(C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C([H])=C3[H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N(C1=C([H])C([H])=C(F)C(Cl)=C1[H])C1=C2C([H])=C(N([H])C([H])([H])C3=C([H])N(N=N3)C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C(Cl)C2=NC([H])=C1C#N
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=C([H])C(=C1[H])C1=C([H])C2=C3N(C(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C3=C1[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C2C(=O)N(C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
CCN1C(C)=C(C(=O)N(CC)C1=O)C1=CC=C(C[C@H](NC(=O)C2=C(Cl)C=CC=C2Cl)C(O)=O)C=C1
C[C@H](OC1=CC=CC2=CC=CC=C12)C(=O)NC1=CC=C2OC(=NC2=C1)C1=CC=NC=C1
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])OC1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])N([H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C(N([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])[H]
[H]N1C([H])=C([H])C([H])=C2N=C(SC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])(C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])N=C12
[H]N(C1=NC(OC([H])([H])[H])=NC(=N1)N([H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(N=C([H])S2)C([H])=C1[H]
[H]C1=C([H])C(C#CC([H])([H])O\N=C2/C([H])([H])[N@@]3C([H])([H])C([H])([H])[C@@]2([H])C3([H])[H])=C([H])C([H])=C1Cl
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1C(=O)C2=C(N=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1S2)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N=C1N(C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@](O[H])(C#CC([H])([H])[H])C([H])([H])C([H])([H])[C@@]21C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(OC([H])([H])[H])=C3C([H])=C([H])C([H])=C([H])C3=C2OC([H])([H])[H])C([H])([H])C1([H])[H]