[H]OC(=O)[C@@]1([H])N([H])[C@@]([H])(C([H])([H])O[H])C([H])([H])C2=C1N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C21
CC1=CC(=CC=C1C(=O)N1CCOC2=CC=C(C=C2C1)C1=CC=C2N=CNC2=C1)S(C)(=O)=O
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C1=O)C(=O)OC([H])([H])[H]
[H]N(C1=NC2=C(N=NN2C2=C1SC([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC(=O)C1=C(N([H])S(=O)(=O)C2=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=N1
[H]N(C(=O)C([H])([H])N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C2C(=C1[H])C([H])([H])[C@]1(N([H])C(=O)N([H])C1=O)C2([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C(Br)N=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C(C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C(=O)C4=C([H])C([H])=C(C([H])=C4[H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])O2
[H]N(C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NON=C1C1=NC2=C([H])C(N([H])[H])=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C2N([H])[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C(N2N=C1[H])(C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C([H])=C(OC(=O)C([H])([H])C([H])([H])[H])C([H])=C1[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(N=C1OC([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]N([H])C1=C(C([H])=C(N(C1=O)C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C([H])N2C1=C(C(=O)C(=O)N([H])[H])C(=C2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N1C(=O)C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NN2C(=N1)N(C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C(=C([N+]#[C-])C2([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=O)N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)N([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(N([H])C(=N[H])N([H])[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(S1)N([H])C1=C([H])C(=NC([H])=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])N([H])C(=O)C2=C(N([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1S2
[H]C1=C([H])C(=C([H])C([H])=C1C1=NC2=C(Br)C(=C([H])C(OC([H])([H])[H])=C2N1C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(C2=C1C([H])=NC(=N2)C#N)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])\[N+]([O-])=O
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)[C@]2([H])N([H])C(=O)N([H])C(=O)C2([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@]1(C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]3([H])C(=O)C4=C(O[C@]3(C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])[C@@]12[H])C([H])=C(OC4=O)C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=C2[H])[C@@]([H])(N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])S2)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N=C(N([H])[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[C@]([H])(N([H])C(=O)[C@@]2([H])N3C(=O)C([H])([H])N(C(=O)C([H])([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@]3([H])C([H])([H])C2([H])[H])C(=O)C2=NC([H])=C([H])S2)C1([H])[H]
[H]N(C1=NN=C2C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2=C1[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C2C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]34C([H])([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@@]4([H])[C@]2([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])SC([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[P@@](=O)(C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])OC([H])([H])[H])[C@]1([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)[C@]2(N([H])C([H])([H])[C@]1(C1=C([H])C(F)=C([H])C(F)=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1(N=C(N([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]N(C(=O)C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C2=C(OC([H])([H])C1([H])[H])C([H])=C(C([H])=C2[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(=N\O[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])\C([H])([H])SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(C(=O)N([H])[C@]1([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[N+]([H])([H])[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C(=O)C1(C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(F)C([H])=C(F)C(F)=C1[H])C1=C([H])C([H])=C([H])N=C1[H]
CCCCCCCCCC[Si](C)(C)CCC(=O)NC(CC1=CC=C(C)C=C1)C1=CC=CC=C1
[H]OC1=NC2=C(N1[H])C([H])=C1C(=C2[H])C([H])([H])[C@]2([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])[C@@]2([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@@]2([H])C2([H])C([H])([H])C2([H])[H])C([H])=C([H])C([H])=C3C1=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(SC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NN=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N1C([H])=NC([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
[H]N(C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)[C@]1([H])C(=O)N2C3=C(C([H])=C([H])C([H])=C13)C([H])([H])C1=C2C([H])=C([H])C(F)=C1[H])C1=NC([H])=C([H])S1
[H]C1=NC2=C(C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C(C(=O)N3C([H])([H])[C@]4(C([H])([H])[H])C([H])([H])[C@@]3([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C4([H])[H])C(Cl)=C2[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1OC([H])([H])[H]
[H]N(C(=O)[C@@]1([H])N([H])[C@]([H])(C(=O)OC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C2=C([H])C([H])=C([H])C([H])=C2S1)C1=C([H])C([H])=C(C(=O)N2C([H])([H])[C@]3(C([H])([H])[H])C([H])([H])[C@@]2([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C(Cl)=C1[H]
[H]O\C(OC([H])([H])[H])=C1\C(=NC(=C(C(=O)OC([H])([H])[H])[C@@]1([H])C1=C([H])C(N([H])C(=O)N([H])C([H])([H])C([H])([H])N([H])C2([H])C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2N=C1C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=NC([H])([H])C2=C1C(OC1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])=NC([H])=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])SC([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C1\C2=C(N([H])C(=C2C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C(N([H])S(=O)(=O)C2=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N([H])C(=O)C1=C([H])N=C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C3([H])[H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@@]([H])(C3([H])[H])[C@]2([H])N([H])S(=O)(=O)C2=C([H])C([H])=C(Cl)S2)C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])C(F)(F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1N=C(N([H])[H])N([H])C2=O
[H]O[C@]([H])(C([H])([H])N1C2=C([H])C([H])=C([H])C(C3=C([H])C([H])=C([H])C(C#N)=C3[H])=C2C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C(OC(F)(F)C([H])(F)F)=C1[H])C(F)(F)F
[H]C([H])=C([H])C1=C([H])C(=C([H])C([H])=C1N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])N([H])C(=S)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([C@]1([H])C(=O)N(C2=C([H])C3=C(C([H])=C2F)C([H])([H])N([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)S1
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=NC2=C(SC(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])N2C1=NC([H])=C2C([H])([H])[H]
[H]N(C1=C([H])C(=NS1)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])N2C1=NC([H])=C2C1=C([H])N(N=C1[H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H]
CC[NH+](CC)CCNc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)NCc1ccc(F)c(F)c1
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N(C(=O)[C@@]([H])(OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[C@@]([H])(N([H])C1=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])SC([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])C2=C([H])C([H])=C(C([H])=C12)C(=C(\F)C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H])\C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1N([H])S(=O)(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)C1=C(O[H])C([H])=C([H])C([H])=C1C2([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C1=NC(=C(N([H])C1=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N1C(=NC2=C([H])C(F)=C(C([H])=C12)C(F)(F)F)C(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])=C1C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(O[H])N=C2C(=N1)C([H])=C(Cl)C(Cl)=C2[N+]([O-])=O
[H]N1C(=O)C2=C(N=C1C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(Br)=C([H])C([H])=C1O2
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])S[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C(S[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2N([H])C([H])=C([H])C2=C1C([H])([H])[H])C1=C(C#N)C([H])=NC([H])=C1C1=C([H])C([H])=C(O1)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N([H])N([H])C([H])([H])C(=C([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)OC([H])(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=NN1C([H])([H])C([H])([H])[H]
[H]N(\C(=C1/C(=O)N([H])C2=C([H])C(=C([H])C([H])=C12)C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C1=C([H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C(C#C[H])=C12)C1=C([H])C([H])=C(C(F)=C1[H])C([H])([H])N1C(=NC2=C1C([H])=C([H])N=C2[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C(=O)N([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C([H])C(F)=C(C([H])=C2N2C([H])=NC([H])=C12)N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C(F)=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)N([H])C(N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C(C1=O)C([H])([H])C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])C#CC2=C([H])C([H])=C3OC([H])([H])C([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(SC([H])([H])C([H])([H])[H])N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)[C@]([H])(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=NN(C1=O)C([H])([H])[H]
[H]N([H])\N=C(\C(=O)N([H])C([H])([H])C([H])([H])SSC([H])([H])C([H])([H])N([H])C(=O)C(=N\N([H])[H])\C([H])([H])C1=C([H])C(Br)=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C(Br)=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C(=N1)C1=NN([H])C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])C(=O)C([H])([H])C([H])([H])[C@@]4(O[H])[C@@]5([H])C([H])([H])C(C([H])=C1[H])=C2[C@@]34C([H])([H])C([H])([H])[N@@+]5(C([H])([H])[H])C([H])([H])C([H])=C([H])[H]
[H]C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])[C@]([H])(C2=C(F)C([H])=C(F)C(F)=C2[H])[C@@]([H])([N+]([H])([H])[H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])SC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N1C(=O)N(C2=C(C(=C([H])C(=C2[H])C(=O)OC([H])([H])[H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N(\C([H])=C(/C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C(=NO1)C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC([H])=NC2=C1N=NN2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N([H])C(=O)C([H])([H])C1=C(N(C2=C([H])C([H])=C(SC([H])([H])C([H])([H])C([H])([H])P([O-])([O-])=O)C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(\N=C(/[H])\C(\[H])=C(/[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C(=O)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]OP(=O)(O[H])C([H])([H])N([H])C1=C([H])C(N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])=C(C([H])=C1[N+]([O-])=O)C(F)(F)F
[H]N(C(=O)C(OC1=C([H])C([H])=C(C([H])=N1)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC([H])=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])[C@]4(OC(=O)N(C([H])([H])C5([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C5([H])[H])[C@@]4([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(=C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H])[C@@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]C1=NC(=C([H])O1)C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(=NN(C1=O)[C@]([H])(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C(=C(OC([H])([H])[H])N=C1C(F)(F)F)C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H])C(F)(F)F
[H]S\C(=N/[C@]([H])(C(=O)OC([H])([H])C(=O)N([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N1C2=C(C([H])=C1C1=C([H])C([H])=C([H])C3=C1C(=O)N([H])C3([H])[H])C([H])=C(OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])=C2[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])[C@]([H])(OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C#N)C(=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C1=NC2=C(N=C(N=C2N=C1[H])N([H])[H])N([H])[H])C([H])([H])C([H])([H])N([H])C(=O)N([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)C1=C(O[H])C([H])=C(C([H])=C1O[H])C(=O)O[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NN([H])C(=N1)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=NC(=C([H])N1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1C([H])=C(OC([H])([H])[H])C(OC([H])([H])C(\[H])=C(/[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C2[H])C1=C(F)C([H])=C(C#N)C([H])=C1[H]
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C(S2)C2=NC([H])=C(S2)C2=C([H])C([H])=C(O[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C(Br)C(=NO1)[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@]1(OC([H])([H])[H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(N([H])C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C2=NC(=NC([H])=N2)N([H])C([H])([H])C#N)=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(N([H])C([H])([H])C2=NC3=C(SC4=C([H])C([H])=C(Cl)C([H])=C34)C(=O)N2[H])=C1C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(C(=O)N([H])C([H])([H])[H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1(C([H])([H])S[C@@]([H])(C2=C([H])C(\C([H])=C(/[H])C3=NC4=C(C([H])=C3[H])C([H])([H])SC4([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])\C(=C(\[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])O2
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=NC([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C2=C([H])C(OC3=NC([H])=C([H])S3)=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]OC(=O)C1=C([H])C(N([H])C(=O)C(\C#N)=C(/[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C([H])=C2C([H])=C([H])C([H])=C(C2=N1)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N([H])C([H])([H])[C@]1([H])N(C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=N/OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C(OC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])\C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])C([H])([H])OC1=C(C2=C(C([H])=C(O2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C([H])C([H])=C2N([H])C(=O)C2=C([H])N=C(Br)S2)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]N1C2=C([H])C(=C([H])C([H])=C2C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]\C(=C(\[H])C([H])([H])N1C([H])([H])C([H])([H])C2=C([H])C(Cl)=C(OC([H])([H])[H])C([H])=C2[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N(C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C2=NC(=NC([H])=C2[N+]([O-])=O)N([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1(OC(=O)C(=C(C([H])([H])[H])C([H])([H])[H])C1([H])[H])C([H])([H])OC(=O)C1=C([H])C([H])=C(C#CC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C(C([H])=C(C([H])=N1)C1=C([H])N(N=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=NC2=C(O1)C(=C([H])C([H])=C2[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C1=NN=C(C([H])=C1[H])N1C([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]2([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(F)=C([H])C([H])=C12
[H]N(C(=O)[C@@]([H])(N([H])C1=C([H])C(=NC(=N1)N1C([H])=NC(=C1[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C2=C(N([H])C([H])=C2C([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C3C(=N2)N([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]\C(=N/C([H])(\N=C(/[H])C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C([H])O1
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=C(C([H])=C1[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])SC(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C(N([H])C([H])([H])[H])C(=O)C1=O)C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)S2)C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H])[C@]([H])(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(F)C([H])=C2[H]
[H]N(C(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])[C@@]1([H])C(=O)N(C2=C([H])C([H])=C([H])C(\C([H])=C(/[H])C(=O)N([H])S(=O)(=O)C3=C([H])C(Cl)=C(Cl)S3)=C12)C([H])([H])[H]
[H]N([H])C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])[C@]12[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(=O)C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1S(=O)(=O)C2=C(C([H])=C([H])C([H])=C2[H])S1(=O)=O
[H]N([H])C1=NC2=C([H])C([H])=C(C([H])=C2[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])OC1=C(Cl)C([H])=C(\C([H])=C2/S\C(=N/C([H])([H])C([H])([H])C([H])([H])[H])N(C2=O)C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])=C1[H]
[H]C1=C(N=NN1C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C1([H])[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C([H])N(N=N2)C([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3S2)=C1[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C(=O)N([H])C1=C([H])C2=C(N([H])C([H])=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C([H])C2=C(N([H])C([H])=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)N([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C(N(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])SC1=NC([H])=C(C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C(=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C(C([H])=NC2=C([H])C([H])=C(C([H])=C12)S(=O)(=O)C([H])([H])[H])C(=O)N([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=NC([H])=C(C([H])=C3[H])C3=NC(=C(S3)C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C3OC([H])=C([H])C3=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])[H]
[H]N(C1=NN2C(=C([H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(OC(=O)[C@@]2([H])C([H])([H])[C@@]3([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C3([H])[H])[C@@]2([H])C(=O)OC([H])([H])[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(N([H])C(=O)C(\[H])=C(\[H])C2=C([H])C([H])=C3C([H])=C([H])N=C(N(C([H])([H])[H])C([H])([H])[H])C3=C2[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]C1=C(SC2=C1C([H])=C([H])C(Cl)=C2[H])S(=O)(=O)N1C([H])([H])C(=O)N(C([H])([H])C(=O)N(C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N([C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)S1)C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(Cl)=NC(Cl)=C2[H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(\C([H])=C2/C(=O)/C(=C(/[H])C3=C([H])C([H])=C(C([H])=C3[H])C(=N[H])N([H])[H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(N=C1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])O1)[C@@]1([H])OC(=O)[C@]2([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]([H])(C4=NN=NN4C([H])([H])C([H])([H])C#N)C([H])([H])[C@]([H])(OC(=O)C([H])([H])[H])C(=O)[C@]3([H])[C@@]2(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C1N=C([H])N2[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(N(N=C1C#N)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(\C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N1C([H])=NC([H])=C1[H])C([H])([H])[H]
[H]OC1=C(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=S)C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C2N(C(=O)C([H])([H])OC2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C(C([H])=C([H])C1=O)C1=C2N=C([H])C(=C([H])N2N=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C(OC(=N1)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C2/OC(=S)N(C2=O)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1Br
CC(C)N1C=NC2=C(NC3=CN=CN=C3)N=C(Cl)N=C12
[H]N([H])C1=C2C([H])=C([H])C([H])=C3C(=O)N(C(=O)C(C([H])=C1[H])=C23)C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])[C@@]2([H])C(=O)N(C(=O)[C@@]12[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C2=C(C([H])=C(N=C2N([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])N2C(=O)C([H])([H])OC([H])([H])C2([H])[H])C(=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N(C(=O)C1=C(N([H])C2=C([H])N=C([H])N=C2[H])C([H])=C([H])C(=N1)C1([H])C([H])([H])C1([H])[H])C1=C([H])C(=NO1)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C2C3=C(N1[H])C([H])=C([H])C([H])=C3C(=O)N([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1\C([H])=C(/[H])C1=[N+](C2=C(C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC2=NC([H])=C([H])N=C2N1C1([H])C([H])([H])C([H])([H])N(C(=O)N([H])[C@]2([H])N=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C(C([H])=C([H])C([H])=C3[H])N(C2=O)C([H])([H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C([H])N2C(=C1[H])C(=O)[C@@](OC1=C([H])C([H])=C([H])C([H])=C21)(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1OC1=NC(OC2=C([H])C(=C([H])C([H])=C2[H])C(=N[H])N([H])[H])=C(F)C(N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1F)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(O[H])C(O[H])=C(C([H])=C1[H])C1=C([H])C(=O)C2=C([H])C([H])=C([H])C(=C2C1=O)[N+]([O-])=O
[H]N(C(=O)C([H])([H])N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N1N=C(C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C2=C(C([H])=C(F)C([H])=C2[H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]12[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1OC1=C([H])C(Cl)=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)C1=NC2=C(O1)C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)N2C([H])=NN=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C1=NC(=NC2=C([H])N=C([H])C([H])=C12)C1=C([H])C([H])=NC([H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C(F)C([H])=C2C(C([O-])=O)=C1C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[C@]1([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1F)N1C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C([H])C(=NC([H])=N2)C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])[C@]1([H])C1=C([H])C(F)=C(F)C([H])=C1F
[H]N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])N=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(OC1=NN=C(N1C([H])([H])[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C2=NN=C3SC([H])([H])C(=NN23)C2=C([H])C(OC3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C(F)=C1[H]
[H]N([H])C(=O)C1(N([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C2=C([H])N=C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C(=N2)C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C1=NC([H])([H])C2=C1C([H])([H])N(C(=O)N([H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2(C([H])([H])[H])C([H])([H])[H])C1=C2C([H])=C([H])SC2=NC(=N1)C([H])([H])[H]
[H]O[C@@](C(=O)N([H])C1=C([H])C([H])=C(C#N)C(=C1[H])C(F)(F)F)(C([H])([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)C3=NC4=C(C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])C2([H])[H])=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(Cl)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@@]3([H])C([H])([H])[C@]1([H])C([H])([H])[C@](C3([H])[H])(C2([H])[H])S(=O)(=O)N([H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC2=C(S1)C([H])=C(OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])=C2[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])[C@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])N(C([H])([H])[C@@]([H])(N([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]OC(=O)C(SC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C(=O)N([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(N(C3=C([H])C([H])=NC([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H]
[H]N(N(C(=O)C1=C([H])C(F)=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])[H])C(=O)N([H])[C@@]([H])(C1=NC([H])=C(C([H])=C1F)C(=O)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]12C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C(\C([H])=C2/S\C(=N/C([H])(C([H])([H])[H])C([H])([H])[H])N(C2=O)C([H])([H])C([H])=C([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C(C(=NC2=C([H])C([H])=C(F)C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])N2C(=C1[H])C(C1=C([H])C(SC(F)(F)F)=C([H])C([H])=C1C([H])([H])C2([H])[H])=C1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]2([H])C([H])=C([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]O[P@](=O)(OC([H])([H])[C@]1([H])O[C@]([H])(N2C([H])=C([H])C(=O)N([H])C2=O)[C@@]2([H])O[C@@]([H])(O[C@@]12[H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])O[P@@](=O)(O[H])O[P@@](=O)(O[H])O[P@@](=O)(O[H])OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=C([H])C(=O)N([H])C2=O)[C@]2([H])O[C@]([H])(O[C@]12[H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])=C1[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(SC([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1[H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C#N)C(=C1[H])C(=O)C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C(Cl)=C([H])C(=C1Cl)S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C([H])=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NC3=C(N2[H])C([H])=C(F)C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=NN1[H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[P@@](=O)(O[H])C1=C([H])C(=C([H])C([H])([H])C1([H])[H])N1N=C(C2=C(N=C([H])N=C12)N([H])[H])C1=C([H])[C@]([H])(OC([H])([H])[H])C([H])([H])C([H])=C1[H]
[H]OC(=O)[C@@]1([H])C([H])([H])N(C(=O)[C@@]1([H])N([H])C(=O)C1=C([H])C2=C(N=C1[H])C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N1C([H])([H])[C@@]2([H])C([H])([H])N(C3=C([H])N=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C3[H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(C#N)=C([H])N1[H])C1=C(C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C1=NN=C(O1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N1C([H])=C(C(=C([H])C1=O)S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(OC(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N1N=C(N(C1=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])C(=O)N(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])N1C(=O)C2=C(ON=C2C2=C1C([H])=C([H])C([H])=C2Cl)C([H])([H])[H]
COC1=CSC=C1C(=O)N1CCC(F)(CNCC2=NC=C(C)C=C2)CC1
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(O[C@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(S1)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(N2N=NC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C([H])C(OC(F)(F)F)=C([H])C([H])=C12)[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(OC(=O)N(C3=C([H])C([H])=C([H])C([H])=N3)C2([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=N[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(N([H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])SC([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[N+]1=C(C([H])=C(C([H])=C1C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C(Cl)=C(OC([H])([H])C(=O)N([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]OC1=C(C(=O)N([H])C2=NC([H])=C([H])S2)C(=NC2=C1C([H])=C([H])C([H])=C2C(F)(F)F)[C@@]([H])(O[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C([H])=C2N=C([H])C(=C([H])C2=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C2=NC(N([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=N2)C([H])=C1[H]
[H]O\N=C1\C(\N([H])C2=C([H])C([H])=C([H])C([H])=C\12)=C1\C(=O)N([H])C2=C1C([H])=C(Cl)C([H])=C2[H]
[H]N(C(=O)N([H])[C@@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C([H])([H])[H]
[H]N(C(=O)C1=C(N(C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C2=C(N=C(O2)C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])C#N)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1(C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C(=O)OC([H])([H])[C@]1([H])OC([H])([H])[C@]([H])(C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=[N+](C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C(OC(=O)N([H])C([H])([H])C([H])=C([H])[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])[C@]1([H])C([H])([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(C(=N[H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]\C(=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[S@@](=O)C1=NC([H])=C(O1)C1=C([H])OC([H])=N1
[H]C1=C(ON=C1C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
CC(C)(CC(O)(CC1=CC2=CC=NC=C2N1)C(F)(F)F)C1=CC(=CC=C1O)C1=CN=CN=C1
[H]OC(=O)[C@@]([H])(OC1=C([H])C(=C(Cl)C([H])=C1[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C([H])([H])OC2=C1C([H])=C(C([H])=C2[H])C1=C([H])C(=NN1C1=C([H])C([H])=C(F)C([H])=C1C([H])([H])[H])C(F)(F)F
[H]N1C(=O)C2(C3=C([H])C(=C([H])C([H])=C13)C1=C([H])C(C#N)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C(F)C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])S(=O)(=O)C1=NC([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)N([H])[C@@]1([H])[C@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=NC3=C(N2C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=C(N=C(S1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C1=NN=C(O1)C1=C(N=C([H])N1C([H])([H])[H])N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])=C([H])C2=C1C([H])=C(Cl)C([H])=C2[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C2C([H])=C([H])N(C2=N1)C1=C([H])C([H])=C([H])C([H])=N1)C1=C(SC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1(C([H])([H])C([H])([H])N2C([H])([H])[C@@]3([H])C4=C(C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C4=C3C(=C([H])C([H])=C4[H])[C@]2([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C2C([H])=C([H])N([H])C2=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])SC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1(C([H])([H])C1([H])[H])C(F)(F)F
[H]N=C1N(C2=C(C([H])=C1C(=O)OC([H])([H])C([H])([H])[H])C(=O)N1C([H])=C([H])C([H])=C([H])C1=N2)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C1=NC([H])([H])C([H])([H])N1[H]
[H]N([H])C1=C2C([H])=C(C(=NC2=NC([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C(=O)N([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C1=C(N=C(O1)C1=C2C([H])=C([H])C(=NC2=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N1N=C([H])C(=C1[H])C1=C([H])C2=C(OC(=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])[H])C([H])=C1[H]
[H]N(N1C([H])([H])C([H])=C(C2=C([H])C([H])=C3N([H])C([H])=C(C3=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C(=S)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])C(=O)N(C1=NC2=C(C([H])=C([H])C([H])=C2S1)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C2=NN(N=N2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])C(=O)N(C([H])([H])[H])[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
FC(F)(F)OC1=CC=C2N(CC3=CC=C(C=C3)C3=CC=NC=C3)C(=O)C(=O)C2=C1
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C([H])=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C1[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N2C([H])([H])C3=C(C([H])=C([H])C([H])=C3OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])[C@@]1([H])C(=O)N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C(F)=C2F)C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N([H])C([H])([H])[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C1([H])[H])C([H])([H])[C@]([H])(O[H])[C@]1([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])([C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)O[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]21[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C([H])N=C12)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C2C([H])=C([H])C([H])=C(N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C1[H]
[H]N(C1=NN=NN1C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])[C@]2([H])[C@@]1([H])[C@]1([H])C([H])=C([H])[C@@]2([H])[C@@]2([H])C(=O)N(C(=O)[C@@]12[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])C#CC1=NC([H])=C([H])S1
[H]N([H])C1=NC2=C(C(=N1)N([H])[H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])N2[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C(C2=C1OC(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C1=C(C#N)C(=NC2=C([H])C([H])=C(F)C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(N=C1[H])N([H])[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C2([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C2O[C@@]3([H])[C@@]([H])(O[H])C([H])=C([H])[C@@]4([H])[C@]5([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C(OC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])C([H])([H])F)C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(OC([H])([H])C#C[H])N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)N(C2=C1C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])[C@]1(N(C(=O)N([H])C1=O)C([H])([H])[H])C2([H])[H]
[H]O[C@](C([H])([H])N([H])C1=C2C([H])=NN(C2=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=NC(C2=NN=C(O2)C2([H])C([H])([H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
CS(=O)(=O)NC1=C2N=C(C=C(O)C2=CC=C1)C(=O)NC1=CC=CC(F)=C1F
[H]N(C(=O)C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)C4=NC5=C([H])C([H])=C([H])C([H])=C5N=C4[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C(=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])OC1=C([H])C([H])=C(Cl)C2=C1C([H])([H])C(=O)N2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)N(C([H])([H])C1(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])[N@@+](C([H])([H])[H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H])[N+]([O-])=O
[H]OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2(N([H])C(=O)C3=C([H])C4=C(S3)C([H])=C(C([H])=C4[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(C([H])=C(N([H])C([H])([H])C2=C([H])N=C([H])N2C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC(=O)C1=C([H])C(O[H])=C(C(=O)C2=C(C([H])=C([H])C([H])=C2O[H])C(=O)OC([H])([H])[H])C(O[H])=C1[H]
[H]C1=C(N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=NN(C(=C2N=C1C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(O[C@]3([H])C([H])([H])N(C([H])([H])C3([H])[H])S(=O)(=O)C3=C([H])C([H])=C(C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])[C@]1([H])C([H])([H])C2=C(C([H])=C(C([H])=C2[H])C(=O)C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C1=C(Cl)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(SC([H])=C1[H])C(=O)C([H])([H])C1=C(C#N)C([H])=C2OC([H])([H])OC2=C1[H]
[H]N([H])C1=NC([H])=C2C([H])=C(C([H])=C([H])C2=N1)C1=C(C([H])=C([H])N(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C1=NN2C(SC1([H])[H])=NN=C2C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1[C@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])(F)C([H])([H])C3([H])[H])C([H])=C2C([H])([H])N(C([H])([H])[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C(F)=C(N([H])C(=O)[C@@]([H])(N2C(=NC3=C2C([H])=C(F)C(F)=C3[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(F)=C1[H]
[H]OC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=S)N([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])[N+]([O-])=O)C([H])([H])C1([H])[H])C(F)(F)F
CN1C=C(C=N1)C1=CC(F)=C(CN2C(=O)C3(CCN(C3)C3CCCC3)C3=C2C=CC=C3)C(F)=C1
[H]C([H])=C([H])C([H])([H])C1=C([H])C(=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C(=C1[H])C([H])([H])C([H])=C([H])[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2Cl)C([H])([H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])[N+]([O-])=O)C1=C(OC([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C(OC([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1C2=C(C([H])=C1[C@@]1([H])C([H])([H])[C@]3([H])O[C@@]([H])(C([H])([H])C3([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H])C([H])=C([H])C([H])=C2[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\C(=O)OC([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])N3[H])C2=C1[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(S1)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F)C([H])([H])[H]
[H]N(C1=C(C([H])=C([H])C(=N1)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1([H])C([H])([H])N(C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]2(C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C1([H])[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C([H])C(N([H])C2=NC([H])=C(S2)C2=C([H])C([H])=C([H])N=C2[H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC(=C([H])S1)C([H])([H])C([H])([H])OC([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(\C([H])=C1/C(=O)C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)[C@@]12C([H])([H])[N@]3C([H])([H])[N@@](C1([H])[H])C([H])([H])C([H])([H])[N@](C3([H])[H])C2([H])[H]
COC1=CC(Cl)=C(NC2=NC(Cl)=CN([C@@H](COCCF)C3CC3)C2=O)C(Cl)=C1
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])N=C1C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]11N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])C(=C(S2)C([H])([H])N1C([H])=NC([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C#N)C(=C1[H])C(F)(F)F
CCN1CCN(CC1)C(=O)C1CCC(=O)N1C1=CC=C(C=C1)C#C[C@]1(CN2CC3=C(C2=O)C(F)=C(OC)C=C3)NC(=O)NC1=O
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C([H])C(=C1[N+]([O-])=O)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C1=O
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])SC2=C(Cl)C([H])=C(O[H])C([H])=C2O[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C(OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C2C(=C1[H])[C@@]13C([H])([H])C([H])([H])N(C([H])([H])C4([H])C([H])([H])C4([H])[H])[C@@]([H])(C2([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]N1C(=O)N([H])C(=C1C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])SC1=NC2=C(N=N1)C1=C([H])C([H])=C([H])C([H])=C1N2C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]1(OC(=O)\C(=C(\[H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C1([H])[H])C([H])([H])OC(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
CC1=CN=C(CNCC2(F)CCN(CC2)C(=O)C2=C3CCCCC3=CS2)C=C1
[H]OC(=O)C1=C([H])C([H])=C(C#CC2=C([H])C3=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])=C3C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)O[C@@]1([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[N+]2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C(=C(C([H])=C1[H])N1C(=O)C2=C(OC([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])N=C3C(OC([H])([H])C([H])([H])[H])=C2C1([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C2=NC([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C(=O)C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C3=C([H])C([H])=C([H])N3[H])C2([H])[H])C(=C1[H])C(F)(F)F
[H]O[C@@]([H])(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[P@](=O)(O[H])[C@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C(N([H])C(=O)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C([H])([H])N([H])[H])C([H])([H])C([H])([H])C(O[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]C1=C([H])C(=C(F)C([H])=C1N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2C(F)(F)F)C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2OC([H])([H])C(=O)OC([H])([H])[H]
[H]N([H])C(=O)[C@@]1([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[C@]2([H])N([H])C(=O)C(N1C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N=C(C([H])=N1)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C(N=C3[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(C1=C2C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(OC([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C2([H])[H]
[H]N([H])C1=N[C@]([H])(N([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C([H])C(=C([H])C([H])=C2N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C1=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=C(N2C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(OC([H])([H])[H])C(C2=NC(=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N2C([H])([H])C([H])([H])F)C([H])([H])[H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C2=C([H])C([H])=C(C3=C([H])C([H])=C([H])C(=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C([H])([H])N1N=C([H])C(Cl)=C1[H])C1=C(C#N)C(=C(S1)C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C([H])C(=C2[H])C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C(C([H])=C3[H])[N+]([O-])=O)C2=O)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=NN2C1=NN=C2C1=C([H])C([H])=C(F)C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=N2)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])[H]
[H]N(N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C(=O)C([H])([H])SC1=NN=C(N1C([H])([H])C1=C([H])C([H])=C([H])O1)C1=C(OC([H])=C1[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])N(C(=O)C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N1C([H])([H])C2=C(N(N=C2[H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)N([H])C1=C([H])C([H])=C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2N=C(C([H])=C(C2=C1[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC([H])([H])C([H])([H])O\N=C2\C(\N([H])C3=C\2C([H])=C([H])C([H])=C3[H])=C2\C(=O)N([H])C3=C([H])C([H])=C(C([H])=C23)S(=O)(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N1C([H])=C(C2=C([H])C([H])=C([H])N=C12)C1=C([H])C(=O)N([H])C(=N1)N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]OC1=NC(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])C([H])(C(=N/OC([H])([H])C([H])([H])[H])\C4=C([H])C([H])=C(Br)C([H])=C4[H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C3N(C(=NC3=C([H])N=C12)C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1(F)F
[H]N(C1=C([H])C2=C(C([H])=C1[H])C([H])=C([H])C1=C(C([H])=C(C([H])=N1)N1C([H])([H])C([H])([H])N(C3=C([H])N=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C2=O)S(=O)(=O)C([H])([H])[H]
[H]N1N=C(N=C1C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C2=NN(N=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=NC(=C([H])C([H])=C2C([H])=C1OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N1C(=O)N(C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C2SC(=C3[H])C2=C([H])N(C([H])=N2)C([H])([H])C([H])([H])[H])C(F)=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=NN([H])C2=NC([H])=C(C([H])=C12)C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C([H])C1=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C2C([H])=C(Cl)C([H])=C([H])C2=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C(C([H])=C3N([H])C(=O)C([H])([H])[H])N3N=NC([H])=C3[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C(OC(F)(F)F)C([H])=C([H])C(N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])F
OC(COC1=CC=CC=C1)CN(CCCN1CCOCC1)C1CCN(CC1)C1=NC=NC2=C1C(=CS2)C1=CC=CC=C1
[H]N(C1=NC2=C([H])C([H])=C(C([H])=C2N2C([H])=NC([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
NS(=O)(=O)C1=CC=C(C=C1)N1N=C(CCO)C=C1C1=CC=CC=C1
[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)[C@@]1([H])C([H])([H])O[C@@]([H])(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(=C1[H])[N+]([O-])=O)C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(O[H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC1=C(C(=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(C1=C([H])C([H])=C(F)C([H])=C1[H])=C1\C([H])([H])N2[C@]3([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@]1([H])C3([H])[H]
[H]N(C(=O)C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(F)=C1[H])C1=C([H])C(F)=C(OC2=C3SC(=C([H])C3=NC([H])=C2[H])C2=C([H])N(C([H])=N2)C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1C2=C([H])C(F)=C(Cl)C([H])=C2[C@](C1=O)(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(C([H])=C(Cl)C([H])=C2O1)C(=O)N([H])[C@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=NC(=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C#N)C(F)(F)F
[H]N(C(=O)N([H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])N2C(=O)N(N=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(N([H])\N=C1/C(=O)C([H])=C(N([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])=[N+]([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=N2)C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(N([H])C(=O)N([H])C2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])[C@]([H])(OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
O\N=C1/C2CCN(CC2)/C/1=C\C1=CN(CC2=CC=CC=C2)C2=CC=CC=C12
[H]N(C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N1C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=C(C3=C(N=C([H])N=C23)N([H])[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C(F)C([H])=C(C(OC([H])([H])[H])=C1[H])[C@@]1([H])C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])C1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C22C([H])([H])C3(OC12C([H])([H])C3([H])[H])C([H])([H])N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(C#CC([H])([H])[H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@@](C#N)(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(F)=C([H])C(=C1[H])C1=NC([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C12
[H]N([H])C1=NC2=C(C([H])=C(\C([H])=C(/[H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])=N2)C(=N1)N([H])[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=NC([H])=C([H])N=C2N1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]OP(=O)(O[H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])[C@]([H])(C1=NC(=NO1)C([H])([H])C1=C([H])C([H])=C(Br)C(Br)=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C(ON=C1C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[C@@]([H])(C([O-])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])N([H])[H]
CC1=CC(\C=C2\C(=O)NC3=CC=CC=C23)=C2C=CC=CC=C12
[H]N1C([H])([H])C([H])=C(C2=C([H])N(C3=C2C([H])=C([H])C([H])=C3[H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]O[C@@]([H])([C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])P(=O)(OC([H])([H])[H])OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2C(=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])[C@@]([H])(C2([H])[H])[C@]1([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1F)C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C#N
[H]OC1=C2O[C@@]3([H])[C@]([H])(N([H])C(=O)C(\[H])=C(/[H])C4=C([H])C([H])=C(C([H])=C4[H])[N+]([O-])=O)C([H])([H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N1C(=C(C(=O)OC([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=NC2=C(C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C3=C([H])C(=C([H])N=C23)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1([H])OC(=O)O[C@]11C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C(Cl)N(N=C2C(F)(F)F)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])=C([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=CC=C(CNC(=O)C2=NN=C(C=C2)N2CCN(CC2)C(=O)C2=CC=CC=C2C(F)(F)F)O1
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC([H])([H])C([H])([H])N1N=NN=C1[C@]([H])(N([H])C(=O)C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]C1=C2C(=C([H])C(=C1[H])[N+]([O-])=O)S(=O)(=O)N=[S@]2C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])N([H])[H]
[H]OC(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(F)=N1)[C@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(\C([H])=C2/SC(=S)N([H])C2=O)C([H])=C1[H])C([H])([H])OC1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])[C@@]1(C2=C(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
NS(=O)(=O)C1=CC(=CC=C1)N1N=C(CO)C=C1C1=CC=CC=C1
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(\[H])=C(/[H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]OC1(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=NN(C(=C2C([H])([H])C(=O)N([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N1C(=O)N(C2=C([H])SC(=N2)C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C2=C(Br)C([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(OC1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@]([H])(C(\[H])=C(/[H])C2=C(C3=C([H])C([H])=C(F)C([H])=C3[H])C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3N=C2C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=C2N=C([H])N([H])C2=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C(C([H])=C(Cl)C([H])=C1[H])N(C(=O)C([H])([H])[H])C2([H])[H]
CCONc1ncc(C)c(n1)-c1cc(C(=O)N[C@H](CO)c2cccc(Cl)c2)n(C)c1
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]OC([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])N(C2=C3C(=NC4=C(C([H])=C(OC([H])([H])[H])C([H])=C24)C([H])([H])[H])N([H])N=C3C([H])([H])[H])C1([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC3=C(S2)N=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])(C(F)(F)F)C(F)(F)F
[H]N1C(=NC2=C([H])C([H])=C(C([H])=C12)S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])OC([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])N=C2C([H])=C([H])C(Cl)=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H]
COC1=CC2=C(CN(C[C@]3(NC(=O)NC3=O)C#CC3=CC=C4C(=C3)C(C)OC3=CC=CN=C43)C2=O)C=C1
[H]C1=C([H])C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C2=C1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1C2=O
[H]N([H])C(=O)C1=C2\C(=N\N([H])C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)N([H])[H])C(=O)N([H])C2=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N1C([H])=C([H])C(=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C(F)=C2[H])C([H])([H])N2C([H])([H])C([H])([H])SC([H])([H])[C@@]2([H])C1([H])[H]
[H]N1C(=C([H])C2=C1C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N=C1N2N=C(SC2=NC(=O)\C1=C(/[H])C1=C([H])C([H])=C([H])N1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])O1
[H]C1=C([H])C([H])=C([H])C(=N1)N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C3=C2OC([H])([H])C([H])([H])O3)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C2N=C(C([H])=NC2=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1N=C(C2=C(N3C([H])([H])C([H])([H])SC([H])([H])C3([H])[H])C3=C([H])C(OC([H])([H])[H])=C([H])C(=C3N=C12)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(N=C1[H])C([H])([H])OC1=C([H])C([H])=C2C(C([H])=C3C(=O)OC([H])([H])C3=C2C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]\C(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1/C(=O)N2C(C([O-])=O)=C(C([H])([H])OC(=O)C([H])([H])[H])C([H])([H])S(=O)(=O)[C@]12[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C(Br)C(=NN1[H])C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C2C3=C(N=C(C([H])=C3N(C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])N1C1=C(C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C2C([H])=C([H])N(C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C(=O)N([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C([H])([H])C1=C([H])C([H])=NC(N([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C1[H])C1=C([H])C2=C(OC(F)(F)O2)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])C(=O)C2=C(OC([H])([H])[H])C(O[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2O1
[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=NC(N([H])[C@]3([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])[C@]3([H])F)=C([H])N=C2C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]1(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N1C([H])=C([H])C2=C([H])C(C(=O)N3C([H])([H])[C@]([H])(N(C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@]3([H])C([H])([H])[H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]C1=C([H])C([H])=C(C(=C1[H])N1C(=C(C2=C1C([H])([H])C([H])([H])N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C2=O)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C(=N1)N([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
CCOC(=O)NNc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(Cl)SC(=C1[H])C1=C(OC(=N1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1F)N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1C([H])([H])[H])C(=O)O[H])C(=O)O[H]
[H]OC1=C([H])C2=C(O[C@@]3([H])C([H])([H])N(C([H])([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])[C@]4([H])C([H])([H])C([H])([H])C([H])([H])[C@]23C4([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N(C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(\C(=N/C#N)N([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=NN(N=N1)C1=C([H])C([H])=C([H])C(=C1[H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]N(C([H])([H])C1=NC([H])=C([H])N1[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=N1)C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C(C([H])=C12)C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])N1C2=C(C([H])=C(C#N)C([H])=C2[H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C([H])([H])[H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)[C@]2(N(C(=O)[C@]1([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C1=NC([H])=NC(N([H])[C@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])N([H])C(=O)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC(=C([H])S1)C([H])([H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C(C2=C([H])C([H])=C([H])C(=C12)C([H])([H])[H])C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C2=O)C([H])([H])C1([H])[H]
[Cl-].[H][C@@]12C[C@@H]3C[C@@H](C3(C)C)[C@]1(C)OB(O2)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)C1=CC(CC2=CC=CC=C2)=CC=C1
[H]N(C(=O)N([H])[C@@]1([H])C(=O)N(C([H])([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]([H])(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC1=C2C([H])=NC(=NN2C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])N([H])C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)N([H])[H])C([H])([H])C1([H])[H]
FC1=CC=C2C=CC=C(N3CCN(CCCCOC4=C(F)C=C5CNC(=O)C5=C4)CC3)C2=C1
[H]N([H])S(=O)(=O)C1=C([H])C(=C([H])S1)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])C([H])([H])N(C2=C([H])C(=NC([H])=N2)N([H])[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])N3C(Cl)=C([H])N=C23)C([H])([H])C1([H])[H]
[H]N(C1=NC2=C([H])C([H])=C(C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N1C2=C(C([H])=C(C([H])=C2[H])[N+]([O-])=O)C2=C1C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1N([H])C(=O)C2([H])[H]
[H]N(C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1(OC(=O)C(=C1C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C1[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(=NC([H])=C1Br)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[C@@]12C(=O)C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C3=NC([H])=C(C([H])=C3[H])C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])([H])[C@@]2([H])C([H])([H])N(C3=C([H])C([H])=C4N=NN(C4=N3)C3=C([H])C([H])=C([H])C(OC(F)(F)F)=C3[H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N2C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C(F)=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C(=O)ON=C1C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)S(=O)(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]O[C@]1([H])C2=C(C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N(C1=C(C([H])=C(C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=S)N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C4=C(OC([H])([H])O4)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(I)C([H])=C1[H])C1=C([H])C(=O)C2=C(N=C(S2)C([H])([H])[H])C1=O
[H]OC([H])([H])[C@@]1([H])N(C2=C([H])C(=C(C([H])=N2)N(C(=O)C(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])[C@@]([H])(O[H])C1([H])[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=C(/[H])C([H])([H])C1=C(O[H])C(Br)=C(C(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])\C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N1C(=O)[C@@](C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C([H])C(=S)O1
[H]OC(=O)C([H])([H])C1=C([H])C(=C([H])C2=C1C(=C(C(=O)O2)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])N=C(N([H])C3=NC([H])=C([H])C(=N3)C3=C(Cl)N([H])N=C3C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2C2=NN(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@](C(=O)N([H])C1=C([H])C([H])=C2C(=O)ON=C(C2=C1[H])C([H])([H])[H])(C([H])([H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2F)C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N([H])C1=C2C([H])=C([H])C(=C([H])C2=NC([H])=N1)C([H])([H])N1C([H])([H])C(=O)N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(Cl)C([H])=C2[H]
[H]N(\N=C(\C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C(=S)SC([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2N=C([H])C(=N2)C([H])([H])C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H]
[H]N1C(=O)N(C2=C(N(C(=N2)C([H])([H])N2N=C([H])C(Cl)=C(Cl)C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)OC([H])([H])[C@@]1([H])O[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]1([H])OC(=O)C([H])([H])[H]
[H]C1=C([H])N2C(=C1[H])C(OC(=O)C([H])([H])[H])=C(SC1=C([H])C(=C([H])C([H])=C21)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)[C@@]1([H])N(C(=O)N([H])C2=NC(=C(S2)C2=C([H])C([H])=C(C(=C2[H])C(F)(F)F)S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]O\N=C(\C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]C1=C(C([H])=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC([H])([H])C2=C1C(OC1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])=NC([H])=C2[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=S)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C([H])([H])C([H])([H])OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=O)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])S(=O)(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=S)C1=NC(C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C(N=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CC1=NC(NC2CCCCC2)=CC(=C1)C1=CNC2=C1C=CC=N2
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])C([H])([H])OC1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])N1C(=O)C2=C(ON=C2C2=C1C([H])=C([H])C([H])=C2Cl)C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])[N@]2C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1C(=O)O[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H][C@@]1(CCCCN1CCC1=CC=CC=C1)[C@H](C(=O)OC)C1=CC=CC=C1
[H]N([H])[C@]12C3=C(N([H])C(=O)C([H])=C3[H])C([H])([H])[C@]([H])(C([H])=C(C([H])([H])[H])C1([H])[H])\C2=C(\[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])N2C([H])=C(N=C2C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=O)N3C(=NC2=C1[H])[C@@]([H])(C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C3([H])[H]
[H]N([H])C([H])([H])C1=C(N2C([H])=C(N=C2N=C1C([H])([H])[H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])[C@@]1([H])[C@@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])SC2=C([H])C(Cl)=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=O)N=C(SC([H])([H])C(=O)N2C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])N1C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C(=O)[C@@]([H])(N([H])S(=O)(=O)C3=C([H])C4=C([H])C([H])=C(Cl)C([H])=C4C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(F)(F)F)S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=C(C(=NC(=C1[C@@]([H])(O[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C(N=NN2C2=C1SC([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1N=C(N(\N=C(/[H])\C(\[H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C1=S)C1=C([H])C([H])=NC([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N([H])C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])[C@]([H])(N([H])[H])C([H])([H])SC([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[C@]3([H])C([H])([H])[C@]3(C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C(=C2OC([H])([H])C1([H])[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C(N=C3[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N1C(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N([H])[C@@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC1=C(C([H])=C([H])C([H])=C1\C([H])=N\N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])=C([H])[H]
[H]C([H])=C([H])C([H])([H])N1C(=O)C2=C(C(=C([H])N2C([H])([H])C1([H])[H])C(=O)O[C@@]([H])(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C(\Cl)=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C([H])=C(C1=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C1=C([H])C(F)=C(OC2=C3C([H])=C([H])N([H])C3=NC([H])=C2[H])C([H])=C1[H]
[H]N(C([H])([H])[C@@]1([H])OC2=C(OC1([H])[H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])\N=C(/S[H])N([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)[C@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])N([H])[C@@]([H])(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C(C([H])=C([H])C([H])=C12)N(C([H])([H])[H])C([H])([H])[H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=NOC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=NC([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1OC([H])([H])[H])C1=NN([H])C(=C1C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C2=C(N([H])C(=C2C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])=C1[H]
[H]OC1=C(OC([H])([H])[H])C2=C(C([H])=C1[H])C1=C3OC([H])([H])OC3=C([H])C3=C1C(N([H])C3=O)=C2[H]
[H]C1=C([H])C(=C([H])C([H])=C1N=C=S)C(=O)O[C@@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)OC([H])([H])[H]
[H]O[C@]1([H])C([H])([H])C2=C([H])C([H])([H])[C@]3([H])[C@@]4([H])C([H])([H])C([H])([H])[C@]([H])([C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C(=O)O[C@]5([H])C([H])([H])[C@]6([H])C([H])([H])[C@@]5([H])C([H])=C([H])C6([H])[H])[C@@]4([H])C([H])([H])C([H])([H])[C@@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N(C3=C(SC2=C1[H])C([H])=C([H])C(C#N)=C3[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(N([H])C(=O)[C@@]([H])(S[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(O[H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(N3C(=O)C4=C(C3=O)C3=C([H])C([H])=C([H])C([H])=C3C([H])=C4[H])C([H])([H])C2([H])[H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]OC1=NC(=NC2=C1C([H])=C(C([H])=C2[H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])C#C[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C2=C([H])C([H])=C(C([H])=C2C2=C1C1=C(C3=C(C([H])=C([H])C([H])=C3[H])C1([H])[H])C1=C2C([H])([H])N([H])C1=O)C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(F)=C(C([H])=C1[H])C1=NC(C(=O)C([H])([H])C2=C([H])N=C([H])C([H])=C2[C@@]2([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C2([H])[H])=C(F)C([H])=C1[H]
[H]\C(=C(\[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])O1
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C(=O)N1C(=O)[C@@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C(=O)OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C(=O)C3=C([H])C([H])=C([H])C4=C3C(=C([H])C([H])=C4[H])C2=O)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(OC([H])([H])C1([H])[H])C([H])=C([H])C(=C2[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]ON([H])C(=O)C1=C([H])C2=C(OC3=C([H])C([H])=C(I)C([H])=C3[H])C([H])=NC([H])=C2S1
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C(S2)C2=NC([H])=C(S2)C2=C([H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N([H])C1=C([H])C(=C(N([H])C(=O)N([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])C([H])([H])N(C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=N3)C([H])([H])C2([H])[H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(O[H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC1=C(C(=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N([H])C1=C([H])C([H])=C(Cl)C2=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1C2=O
[H][C@@]12CC(=O)CC[C@@]1([H])C(C)(C)OC1=C2C(O)=CC(=C1)C1(CCC1)\C=C/CCCC
CCN1C(=O)C2=C(N=C(N2)C2=CC=CC=C2Cl)C2=C1C=C(Br)C=C2
[H]N(N(C(=O)OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C(OC([H])([H])[H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C#CC([H])([H])SC2=NSN=C2[C@]2([H])C([H])([H])[N@]3C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(O1)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=[N+]3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(\C([H])=C2/SC(=NC2=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C(Cl)C([H])=C1OC([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[C@@]1([H])OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1(F)C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C(N(C3=C([H])C([H])=C(Cl)C([H])=C23)C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(Cl)C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])N([H])C(=S)N([H])[C@@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NOC2=C1C([H])=C(C([H])=C2[H])N1N=C(C2=C1C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(F)(F)F
[H]C1=C(N(C2=C([H])C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C12)S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C([H])C2=C1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C1C2=O
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CNC(=O)CCC1=[N+]2C(C=C1)=CC1=CC=C(N1[B-]2(F)F)C1=CC=CS1
[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C(=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C(\[H])=C(\[H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1O[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])SC1=C([H])N=C(S1)N([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)C1=C(C(=O)C2=C([H])C([H])=C([H])C([H])=C2O1)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)N([H])C(N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])C2([H])[H])=C(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C(=O)C2([H])[H])C([H])([H])C1([H])[H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C(F)(F)F
[H]C([H])=C(C1=C([H])C([H])=C([H])C(=C1[H])C(N([H])C(=O)N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C([H])=C(N=C1N([H])[H])[C@]1(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(N=C1[H])C(F)(F)F
[H]C1=C([H])C(OC([H])([H])C([H])([H])OC2=C(N=C(C([H])=C2[H])C([H])([H])[H])[N+]([O-])=O)=C(OC([H])([H])[H])C([H])=C1Cl
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C(Cl)N=C23)N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N2C(=O)[C@@](N([H])[H])(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C1([H])[H])C(=O)C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]C1=C(N(C(=C1C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N1C(=O)C([H])([H])OC2=C([H])C([H])=C(C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3C([H])=C([H])C(=NC3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])(C([H])([H])O[H])C([H])([H])O[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])[C@]1([H])O[H])C1=C([H])C([H])=C(Cl)C(=C1[H])C([H])([H])C1=NC([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@](C1=C([H])N=C([H])N1C([H])([H])[H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C(=O)C(C#N)=C([H])N2C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(N2C([H])=C(Cl)C([H])=C(Cl)C2=N1)C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CC1=CC(=C(C)C=C1)C1(O)CCN(CCCC(=O)C2=CC(C)=CC=C2C)CC1
[H]OC1=C([H])C(N([H])C2=C(C(=O)N([H])C2=O)C2=C([H])C([H])=C([H])C(Cl)=C2[H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=N2)C([H])([H])S(=O)(=O)C2=C1C([H])=C([H])C(Cl)=C2[H]
[H]N(C1=C2C([H])=NN(C2=NC([H])=C1C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C(N=C(S1)C#CC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[C@]1([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])[C@]([H])(OS(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C2=C(C([H])=C(C([H])=C2C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])OC(SC([H])([H])C([H])([H])[H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2O[C@@]([H])(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])[C@]([H])(SC2=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]ON([H])C(=O)C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])[C@@]([H])(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C2=C(C([H])=C1[H])N(C1=C2C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C(=C([H])C(=C2C2=C3C([H])=C([H])C([H])=C([H])C3=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=N2)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C(=O)OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])SC(=S)SC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])SC([H])=C1[H])C1=NC2=C([H])C([H])=C(C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])N2C(=O)C3=C(N=C([H])N=C3OC([H])([H])C2([H])[H])N([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C(=O)[C@@]([H])(N(C(=O)C([H])([H])N([H])C(=O)[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C(=O)O[H]
[H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC1=NN=C(O1)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2=O)C([H])([H])C#CC1=C([H])C2=C(C([H])=C1[H])N1C(=NN=C1C([H])([H])N=C2C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C3=C(C([H])=NC(=N3)C3=C([H])C([H])=C(C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@](C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C(F)(F)C1([H])[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C([H])([H])N1C2=C3C(N([H])C(=O)C([H])([H])[C@@]3(C([H])([H])[H])C1([H])[H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])[C@@]1(C(=O)N([H])C3=C1C([H])=C([H])C([H])=N3)C2([H])[H]
[H]C1=C(N(C(=C1C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C(=C([H])N2[C@@]1([H])C([H])([H])N([H])[C@@]([H])(C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=S)S\C(=C(\[H])C2=C([H])C3=C(N([H])C(=N3)C3=C([H])C([H])=C([H])C(=N3)C3=C([H])C([H])=C(C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C1=O
[H]N1C([H])=C(C2=C([H])C(C#N)=C([H])C([H])=C12)C([H])([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])N(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=NC([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C2=C([H])C(Br)=C(O[H])C(Br)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[C@]1(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C(SC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]\C(=C1/C(=O)N2C(=C([H])S[C@]12[H])C([O-])=O)C1=C([H])N2C(SC3=C2C([H])([H])C([H])([H])C3([H])[H])=N1
[H]OC(=O)[C@@]1([H])[C@@]([H])(C2=NC(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2[C@]1([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]OC(=O)C1=C(O[H])C([H])=C([H])C(Cl)=C1[H]
[H]C1=C([H])C(=C(C([H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(N([H])C(=O)C1=C(OC(=C1[H])C([H])([H])[H])C([H])([H])[H])C(\[H])=C1/C([H])=C([H])C(=O)C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NN(C2=C1C([H])=C([H])C(OC1=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C13)=C2[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(C(=O)C2=O)C([H])([H])C([H])([H])C(O1)(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC2=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C(=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])OC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]([H])(N([H])C1=C([H])C(=NC(OC2=C(C([H])=C(Cl)C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C(=O)N([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])N=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C(F)=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C(=O)OC([H])([H])[H]
[H]O\C(OC([H])([H])[H])=C1/N(C2=C([H])C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])(C4=C([H])C(OC([H])([H])[H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])=C([H])C([H])=C2[H])C(C(=O)OC([H])([H])[H])=C(N=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])OC([H])([H])C1=C(C([H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C2C(=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N1C([H])=NC2=C1N([H])C([H])=NC([H])([H])[C@@]2([H])O[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C([H])([H])O[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])N([H])C2=C([H])C([H])=C([H])C([H])=N2)C1([H])[H]
[H]C1=C([H])C([H])=C2C([H])=NC(=NC2=N1)C1=C([H])C(F)=C([H])C(=C1[H])C([H])([H])[H]
CN1N=CC=C1C1=CC2=C(SC3=C(CC2N2CCN(C)CC2)C=CC=C3)C=C1
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C2=C(C([H])=C1C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N3C4=C([H])C([H])=C([H])C5=C4C(=C([H])C([H])=C5[H])S3(=O)=O)C([H])([H])C1([H])[H])C([H])=C(F)C([H])=C2[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@@](N(C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])C2([H])[H])(C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])N=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2C2=C1C(=O)N([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C(N(C2=C([H])C(=C([H])C([H])=C12)C1=C([H])N=C([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N1C([H])=C(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C1=C([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(SC(=C2C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])OC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C(F)C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1F)C(F)(F)F
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C3=C(C([H])=C([H])C([H])=C3[H])N(C1=O)C([H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2O1)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])N=C(Br)C([H])=N1
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C#CC([H])([H])N1C([H])([H])C2=C(N(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])([H])C1([H])[H]
COC1=CC=C(C=C1)C1=NNC(NC(=O)CCCCN2CCCNCC2)=C1
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@@]3([H])C([H])([H])[C@]1([H])C([H])([H])[C@](O[H])(C3([H])[H])C2([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])N1C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C(C([H])=C1Cl)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])N(C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=C([H])C2=C([H])C([H])=C([H])C(\C([H])=C(/[H])C3=NC4=C(C([H])=C([H])C(Cl)=C4[H])C([H])=C3[H])=C2C([H])=C1[H]
COC1=C(OCCC(=O)NC2=CC=C(Cl)C=C2)C2=C[N]3=C(C=C2C=C1)C1=CC2=C(OCO2)C=C1CC3
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@@]1([H])N(C([H])([H])C2([H])[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@]([H])(OC(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]2([H])C1([H])[H]
[H]OC(=O)C1=C(O[H])C([H])=C2C3=C(C4=C(N3[H])C([H])=C([H])C(=C4[H])C(F)(F)F)C([H])([H])C([H])([H])C2=C1[H]
CN1N=CC2=CC=C(C=C12)C1=CC=C2OCCN(CC2=C1)C(=O)C1=CC=C(C=C1)C(C)=O
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NN(C(OC([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C(=O)N([H])C2([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)N1C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C(C([H])=C3[H])C(=O)C3([H])C([H])([H])C3([H])[H])C([H])([H])[C@]1([H])C2([H])[H])C([H])([H])[H]
[H]C1=C2N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(N(C3=NN(N=N3)C([H])([H])[H])C([H])([H])C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C2=NC(=C1[H])C(F)(F)F
[H]N(C([H])([H])[H])[C@]1([H])C([H])([H])C2=C([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])[C@]5([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[C@]45C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1C(=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(=O)N1C([H])([H])C([H])([H])[C@@]([H])(N2C3=C(N=C2C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C3[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N=C2C([H])=C([H])C(F)=C([H])C2=C1[H])C([H])([H])[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]C1=C([H])C2=C(S1)C(=NC1=C(N=NN21)S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@@]([H])(C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])[C@@]1([H])N(C([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC4=C([H])C([H])=C5C(=C4[H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C6=C(C([H])=C([H])C([H])=C6[H])[C@]54[H])=C([H])C([H])=C13)C([H])([H])C2([H])[H]
[H]N1N=NN=C1C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C(=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])SC1=NC([H])=C([H])C([H])=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C2=C1OC([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])=C(C(=NC1=O)N([H])C([H])([H])C([H])([H])C(=O)N([H])C1=NC([H])=C([H])N1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])S[C@]([H])(C1=C([H])C(OC([H])([H])C2=NC3=C([H])C(Cl)=C([H])C([H])=C3C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])O[H]
CC(C)N1CCC(CC1)OC1=CC=C2N3CCCNC(=O)C3=CC2=C1
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])C2=NC3=C(OC4=C3C([H])=C(Br)C([H])=C4[H])C(=O)N2[H])C([H])([H])C1([H])[H]
[H][C@@]12C[C@@H]3C[C@@H](C3(C)C)[C@]1(C)OB(O2)[C@H](CCCCN)NC(=O)CN1N=C(CNC=O)N=C1CC1=CC=CC=C1
[H]O[C@]1([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[C@@]1([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC([H])([H])C([H])([H])N(C1=NC([H])=NC2=C1OC1=NC(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C3C(=C21)C([H])([H])C(OC3([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])N2C2=C(C([H])=C([H])N=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C2=C(N=C([H])C([H])=N2)N=C1[H])C([H])([H])[C@]([H])(C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C(C(=O)N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C(N2[H])C2=NN([H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C1=C(ON=C1[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C([H])=C([H])C([H])=N2)N2C(=O)N(N=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C2C([H])=C(C(=O)N(N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C2=N1)C1=C([H])C(F)=C(OC([H])([H])[H])N=C1[H])C([H])([H])[H]
[H]C1=C(Cl)C([H])=C(C(=C1[H])C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]C1=C([H])C(Cl)=C([H])N2C1=NC(=C2C([H])([H])C(=O)OC([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C(N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(C#N)=C([H])N=C2C([H])=C1[H]
CN1C2=C(C=CC=C2)C(=C1S(=O)(=O)C1=C(F)C=CC=C1)S(=O)(=O)N1CCC(CNS(=O)(=O)C(F)(F)F)CC1
[H]C1=NN(C(=O)C([H])=C1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(N=C(C([H])=C2[H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])[H])C(=N1)N([H])[H]
[H]SC1=NC2=C([H])C([H])=C(C([H])=C2C(O1)(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(C#N)=C([H])C(Br)=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1=O)C([H])([H])[C@]1([H])OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])C(=O)C2=C(O1)C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2O[H]
[H]N1C2=C([H])C(=NN2C2=C([H])C([H])=C([H])C([H])=C2C1=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C(C([H])=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])[H]
[H]N1C(=O)O[C@@](C1=O)(C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C2=NOC3=C2C([H])=C([H])C(OC([H])([H])[H])=C3[H])C2=C([H])C([H])=C(C([H])=C12)C(F)(F)F)C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C3=C(Cl)C([H])=NC(=C3[H])N3C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])N(N=C4[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C3([H])[H])C([H])=C21)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C2OC([H])([H])OC2=C([H])C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])C2=C([H])C([H])=C3C(OC([H])([H])C3([H])[H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])C1=C(F)C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(C2=NN=C(N2C([H])([H])[H])[C@@]23C([H])([H])C([H])([H])[C@@](C([H])([H])C([H])([H])C([H])([H])[C@]([H])(F)C([H])([H])[H])(C([H])([H])C2([H])[H])C([H])([H])C3([H])[H])=C(C([H])=C1[H])C(F)(F)F
[H]OC([H])([H])C1=C([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C(=O)N(C([H])([H])C(=O)N([H])[C@@]2([H])C([H])([H])C(=O)O[C@@]2([H])O[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[C@@]1([H])O[C@]([H])(O[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@@]1([H])O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])([H])C2=C(C3=C([H])C([H])=C([H])C([H])=C3S2)C([H])([H])[C@]1([H])C(=O)OC1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]C(=O)C1=C(SC2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(C([H])=C1[H])C1=C(S2)N=C2N(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N1C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C(=C1C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C(Cl)=C([H])N=C(N([H])C([H])([H])C(F)(F)C2=NC([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1N=NN=C1[H]
[H]OC1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C(=C(C#N)C(=N1)N([H])[H])C1=C([H])C(N([H])C(=O)[C@]([H])(O[H])C([H])([H])C([H])([H])C([O-])=O)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=NC([H])=C1\C([H])=C1\C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C([H])=C2C#N)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])OC(=C1[H])S(=O)(=O)N([H])[H]
[H]N1C2=C(C(OC([H])([H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(C#N)(C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C2=NC([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C2C(=C1[H])N(N=C2C(=O)OC([H])([H])C([H])([H])[H])C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C2C(=C1[H])C(=C(C([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])SC2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C4C(ON=C4C([H])([H])[H])=C3C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C(C2=C(N=C([H])N=C2O1)N([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])N1C(=O)N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]23C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2([H])[H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(\C(=N\C1=C(C([H])=C(Br)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C2C(N([H])C([H])=C2S(=O)(=O)C2=C(Cl)C([H])=C(F)C([H])=C2[H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N1C2=C(C([H])=C(Cl)C([H])=C2[H])[C@@]2(N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C3=C2N([H])C2=C([H])C(Cl)=C(F)C([H])=C32)C1=O
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])[C@](C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C(C2=C(C([H])=C([H])C([H])=C2[H])N1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])S[H]
[H]N(C([H])([H])C([H])([H])OC1=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])N=C2N(N=C(C2=C1N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=NC([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C2C([H])=C(OC([H])([H])[H])C(C#CC3=NC(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])C2=NC([H])=C1C#N
[H]N([H])C1=NC(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C1=C(N2[H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]OC1=C(O[H])N=C2C(=N1)C([H])=C(C([H])=[N+]2[O-])C([H])([H])[H]
[H]C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)OC([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
Cl[H].CC1=C(N(N=C1C(NN1CCCCC1)C(F)(F)F)C1=CC=C(Cl)C=C1Cl)C1=CC=C(Cl)C=C1
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(N(N=C1C([H])([H])[H])C1=C([H])C(Cl)=C(C#N)C([H])=C1[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])N([H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC1=CNC2=C1C=CC=C2)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCC(O)=O)C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=NC(C2=C([H])C([H])=C([H])O2)=C(S1)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C1/C2=C([H])C([H])=C(Cl)C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C1=C2N([H])C3=C(C([H])=C(F)C([H])=C3F)C2=[N+](C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2[H])C#N)N1C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=NOC(=N1)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C2=C(C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=NC(=NC(Cl)=N2)N([H])C([H])([H])C(=O)OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(C#N)(C1([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C([H])C(F)=C3[H])C([H])([H])[C@]12[H])C1=C([H])C(=C(F)C([H])=C1[H])C(F)(F)F
[H]N(C(=O)[C@@]1([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H]
[H]N([H])C1=C2C(SC(=C2C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])N=C2[H])=NC([H])=N1
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C2=C([H])C([H])=NC(=N2)N2C([H])=NC([H])=C2[H])C([H])([H])C([H])([H])N(C2=NC(F)=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=NN1C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]S\C(=N/C([H])([H])[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])N(N=N1)C([H])([H])C1=C([H])C(Br)=C(Br)C(Br)=C1[H]
[H]N1C([H])=C(C2=C([H])C([H])=C([H])N=C12)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]([H])(N([H])C1=NC([H])=NC2=C1N=C([H])N2[C@]1([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]1([H])O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
CNC(=O)\C=C1\COC2=CC(OS(=O)(=O)C3=CC=C(C=C3)C(C)=O)=CC=C12
[H]N(C1=NC2=C([H])C([H])=C(Cl)C([H])=C2C(=N[C@@]1([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C(Cl)C(Cl)=C(Cl)S1
[H]N([H])C1=NC(N([H])[H])=C(OC([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])=N1
[H]C1=C(C2=NOC(=N2)C([H])([H])N(C([H])([H])[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C(Cl)=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(N([H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2[H])N(C2=C([H])C3=C(C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])[C@]([H])(C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC(=C([H])S2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])O1
[H]OC(=O)C1=C(C(=NN1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[N+]([O-])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1
[H]O\N=C(/C1=C([H])C([H])=C(C([H])=C1[H])C(=O)O[H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@](C([H])([H])[H])(C([H])([H])N([H])C(=O)[C@]1([H])C([H])=C2C3=C4C(N([H])C([H])=C4C([H])([H])[C@@]2([H])N(C([H])([H])[H])C1([H])[H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H]
[H]N(\C([H])=C1/SC2=C([H])C([H])=C([H])C([H])=C2C1=O)C1=C([H])C([H])=C([H])C2=C1N=C([H])C([H])=C2[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(Br)C([H])=C(\C([H])=C(/[H])C2=C([H])C(=NO2)C([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]ON([H])C(=O)[C@@]1([H])OC([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C(=NN1[H])C([H])([H])[H])C1=NC(=NN2C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C(F)C([H])=C(OC([H])([H])[H])C([H])=C2F)C([H])([H])C1([H])[H]
[H]\C(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])=C1\C([H])([H])N2[C@]3([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]1([H])C3([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C(C(=O)OC([H])([H])C([H])([H])[H])C(=C1C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])N([H])C([H])=N1)[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(S1)C(=NN(C2=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]1([H])C([H])([H])N([H])[C@]([H])(C(=O)N2C([H])([H])SC([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C(C([H])=C(C2=N1)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[C@]([H])(C([H])=O)C([H])([H])C(=O)O[H])C([H])=C1[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2N(C(SC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C(=C3[H])[N+]([O-])=O)=NC2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])N1C(=NC2=C1C([H])=C([H])N=C2[H])C([H])([H])[H])C1=NC2=C([H])C(F)=C([H])C([H])=C2S1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C(=NN1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=NC2=C1C(=C(N2[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C(=O)N([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C(O[H])=C([H])C([H])=C2C11C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]N([H])C(=NOC([H])([H])C1(C([H])([H])OC2=C([H])C(OS(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3S(=O)(=O)C([H])([H])[H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])N([H])[H]
[H]SC1=NN=C(S1)N([H])C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(OC3=C(C(=C([H])C(OC([H])([H])[H])=C3[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)O2)C(=C1C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(OC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C(=NN=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C2C(=C3C([H])([H])C([H])([H])[C@@]4(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@@]4(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@]3([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1=O
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@@]([H])(C(\[H])=C(/[H])C2=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3F)C([H])=C(Cl)C([H])=C2Cl)C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]2([H])C3=C(C([H])=C([H])C([H])=N3)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N1[C@@]2([H])C(C(=O)N(C([H])([H])[H])C([H])([H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])=C(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C4=C(OC([H])([H])[H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])[C@]1([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]2(C([H])([H])OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]3([H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]12OC3(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C([H])C(=C1[H])C1=C(C(=O)OC([H])([H])C([H])([H])[H])C(=NC(=C1C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C(C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC(=NO1)C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1(N(C(=O)C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C2=C([H])C([H])=C([H])S2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C3=NC([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C4=C([H])C([H])=C([H])C(C(=O)C2=C1[H])=C34
[H]N([H])C1=NOC2=C1C([H])=C(C([H])=C2[H])N1N=C(C2=C1C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=N2)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(SC([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C(=O)OC([H])([H])[H])=NN=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@](OC(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])(C1=NC([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C(C(=NN2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C([H])C([H])=N2)C1=O
[H]C1=NC2=C(N=C(OS(=O)(=O)C(F)(F)F)C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C([H])C(=N1)N(C(=O)[C@@]12[C@@]3([H])[C@@]4([H])[C@]1([H])[C@@]1([H])[C@]2([H])[C@]3([H])[C@@]41I)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@]1([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N1C(=O)C2=C([H])C(I)=C([H])C([H])=C2N(C(=O)[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2OC1=O)[N+]([O-])=O
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])[C@]1([H])O[H])C1=C([H])C([H])=C(Cl)C(=C1[H])C([H])([H])C1=C([H])N=C(OC([H])([H])C([H])([H])[H])N=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(F)(F)C(F)(F)F
[H]N1N=C([H])C(=C1[H])C1=C([H])C([H])=C2N=C([H])C3=C(N(C(=O)C([H])=C3[H])C3=C(C([H])=C(F)C([H])=C3[H])C(F)(F)F)C2=C1[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(SC([H])=C1[H])C(\[H])=C(/[H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N1C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C(=O)N(C1=C(Cl)C(=C(Cl)C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])N2C(Br)=C(N=C12)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]12C([H])([H])C([H])([H])[C@](C3=NC4=C(N3[H])C3=N[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])N3C(=O)N4C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C(=S)S\C(C1=O)=C1/C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C(=O)O[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=NC(=C([H])S1)C(=N[H])N([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC1(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N2C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]2([H])C2=C(C3=C(N2[H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(ON=C1C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])SC1=NN=C(N1C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])[C@]1([H])C([H])([H])N(C2=C3C([H])=C(OC3=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2C(=O)N(C(=O)N([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]OC(=O)C1=C(N([H])S(=O)(=O)C2=C(C([H])=C(F)C([H])=C2[H])[S@](=O)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]12C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C2=C(N([H])C3=C2C([H])=C([H])C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]OC1=C(Cl)C([H])=C(C([H])=C1[H])C(=N\C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H])\N([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]2([H])N(C(=O)[C@]([H])(N(C(=O)[C@@]3([H])N(C(=O)[C@]4([H])N(C(=O)[C@]([H])(N([H])C1=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])[C@]2([H])OC(O[C@@]2([H])[C@@]1([H])OC(=O)C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C(OC([H])([H])[H])C(=C([H])C([H])=C1N([H])S(=O)(=O)C1=C(N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C(F)C([H])=C1[H])C1=C([H])OC([H])=C1[H]
[H]OC(=O)C1=C(N=C2C([H])=C([H])C(Br)=C([H])C2=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C(C([H])=C(O1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]\C(=C(\[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(\C([H])=C(/[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@]2([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(OC([H])([H])[H])C([H])([H])OS([O-])(=O)=O)[C@]([H])(Cl)C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C3=C([H])C([H])([H])[N+](=C(N([H])[H])N([H])[H])C3([H])[H])C([H])([H])[C@]2([H])C([H])([H])[C@]1([H])O[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C([H])=C(Cl)C(=C2[H])C([H])([H])C2=NN=C(S2)C2=C([H])C([H])=C([H])S2)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])O[C@]2([H])C3=C([H])C(Br)=C([H])C(F)=C3N([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]2([H])C([H])([H])C1([H])[H]
COC1=CC=C(C=C1)C1=NNC(NC(=O)C(C)CCCN2CCCN(CC2)C(C)=O)=C1
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1F)C1=NC(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(S1)C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C([H])([H])C(=O)N1[C@]([H])(C(=O)O[H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]4([H])C([H])([H])C([H])([H])[C@@]5(O[H])[C@]6([H])N(C([H])([H])C7([H])C([H])([H])C7([H])[H])C([H])([H])C([H])([H])[C@@]55C7=C(C([H])=C([H])C(O[H])=C7O[C@@]45[H])C6([H])[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])N(N=N1)[C@]1([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]1([H])OC(=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C(OC3=C(C([H])=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C3[H])C2=O)C([H])=C1[H]
[H]C1=C(N(C(=C1C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C2N=C([H])C(Br)=C([H])N2N=C1C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N([H])C([H])([H])[H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])C([H])([H])SC([H])([H])[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C(=O)N1C(SC([H])([H])[H])=NC2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C12
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C([H])([H])N(C(=O)C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C(=O)[C@]([H])(N([H])C(=O)[C@]1([H])C([H])=C([H])[C@@]([H])(N2N1C(=O)[C@@](N([H])[H])(C2=O)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]C1=NN(C2=C([H])C([H])=C(C([H])=C12)N1C([H])=C([H])C(=C([H])C1=O)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@@]1(C2=C([H])C([H])=C(C([H])=C2[H])C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C(C([H])([H])C#N)(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1N=C([H])C(OC2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)=C1[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C2=NN=C(N2C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C2=NOC(=C2C(=O)N(C2=C([H])C(Cl)=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=NC(=C(C(=O)OC([H])([H])[H])[C@]2([H])C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
O=C(Cc1ccc(OCC[NH+]2CCCC2)cc1)Nc1cc(n[nH]1)C1CC1
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F)C([H])([H])C(F)(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C(=O)C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C2=C([H])C(=C([H])C([H])=C2OC1=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])[H]
[H]OC([H])([H])C(N([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=[N+]1[O-])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])O[H])C([H])([H])O[H]
OB1OCC2=CC=C(OC3=CC(=CC=C3)C(O)=O)C=C12
[H]N([H])C1=N[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])O1
[H]O[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])S2(=O)=O)C([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C(Cl)C([H])=C2C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])N(N=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC(=O)[C@]([H])(OC1=C(C(O[H])=C(C([H])=C1Cl)C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C([H])=C(C2=C([H])C([H])=C(F)C(F)=C12)C([H])([H])N(C(=O)C1=C(ON=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=NN=C([H])S1
[H]O[C@]1([H])[C@@]([H])(N([H])C([H])([H])[C@@]2([H])C([H])([H])[C@]2([H])OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])S(=O)(=O)C([H])([H])[C@@]1([H])C([H])([H])C1=C([H])C(OC([H])(C(F)(F)F)C(F)(F)F)=C(N([H])[H])C(F)=C1[H]
[H]C1=C([H])C([H])=C(S1)[C@]([H])(OC(=O)C([H])([H])[H])[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N([H])[C@]([H])(C(=O)N([H])C1(C#N)C([H])([H])C1([H])[H])C([H])([H])C(F)(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C([H])(F)F
[H]OC1=NC2=C([H])C([H])=C(Cl)C([H])=C2N2N=C(N=C12)C(=O)OC([H])([H])C([H])([H])[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1F)C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=C([H])C([H])=C2C([H])=C([H])N(C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H]
[H]O[C@](C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H])(C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=N2)C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C3=C([H])C(F)=C([H])C([H])=C3N2C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=S)N([H])\C(C1=O)=C1/C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C1=NC(=NC2=C1N=NN2C1=C([H])C([H])=C(C([H])=C1Br)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C(C#N)C([H])=NN2C(=N1)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1N=C(C2=C1C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C1(C3=NC([H])([H])C([H])([H])O3)C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C(F)(F)F
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])N([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])C2=C(SC3=C(F)C([H])=C(Cl)C([H])=C3[H])C3=C(C([H])=C(F)C([H])=C3N2C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])O[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]2([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]2([H])N(C1=O)C([H])([H])C([H])([H])C2([H])[H])C(=O)N([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])N([H])[H]
[H]OC1=C(C([H])=C(F)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@](O[H])(C([H])([H])N([H])C1=C([H])C([H])=C([H])C2=NC(=C([H])C([H])=C12)C([H])([H])[H])C(F)(F)F
[H]N([H])C1=NC(=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC([H])=C1C([H])([H])[H])N([H])C([H])([H])C(F)(F)C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H]
[H]N([C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N([H])C1=C2N=C(C3=C([H])C([H])=C(N([H])C(=O)N([H])C4=C([H])C(=C([H])C([H])=C4F)C(F)(F)F)C([H])=C3[H])C([H])([H])C([H])([H])N([H])C2=NC([H])=N1
[H]N(C(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(N=C(S1)C([H])([H])[H])C#CC1=C([H])N=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC(=C1C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])[H])[C@]([H])(O[H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC2=C(N(N=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N2C(=O)C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])C(=O)C1=NC([H])=C([H])S1
[H]N([H])[C@]([H])([C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])OC1=C(F)C([H])=C(F)C([H])=C1[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(=O)C1=C([H])C(OC(=O)C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N2C3=C(C([H])=C([H])C([H])=C3C([H])([H])[C@@]2([H])C([H])([H])C1([H])[H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C2=C(C([H])=C([H])S2)C2=C(C(=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])OC2=C([H])C([H])=C([H])C3=C2N=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C(Cl)=C(C([H])=C1[H])C1=NC2=C(OC3=C([H])C([H])=C(Br)C([H])=C23)C(=O)N1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]([H])(OC([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1\C(=N/C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])N(C2=C([H])C(Cl)=C(Cl)C([H])=C12)C([H])([H])C([H])([H])C([H])([H])[H])C1=NN=NN1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=NN=C1SC([H])([H])N1C(=O)C2=C(C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2S1(=O)=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C(=C1C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C(=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC(=O)C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=NC([H])=C(S1)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(C1=C(Cl)C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=NC(=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)S(=O)(=O)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N(C1=NC([H])=C([H])N1[H])C1=NC2=C(C#N)C([H])=NN2C(=N1)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C2C([H])=C([H])C(=C([H])C2=C([H])C([H])=N1)C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NC2=C(S1)C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1=C(N([H])C(=O)C2=C([H])C3=C(N2[H])C([H])=C([H])C(Cl)=C3[H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(Br)=C([H])C(=C1[H])C([H])([H])OC1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C(Cl)C(N([H])[H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=NC3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N(C([H])([H])[H])[C@@]1([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC2=C(N=NN2C2=C1C([H])=C([H])C([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C(C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])N1C(=C([H])C(\C([H])=C2/SC(=S)N(C2=O)C([H])([H])[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@@]3(O[H])C3=C([H])C([H])=C4C(=C3[H])C([H])([H])[C@](C#N)(C(=O)OC([H])([H])C([H])([H])[H])C4([H])[H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])SC1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])OC4=C5C([H])=C([H])C([H])=C([H])C5=C([H])C([H])=C34)[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C2C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C([H])C2=N1
[H]N(C(=O)N([H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N2[H])C(=O)C1=C(Cl)C([H])=C(F)C([H])=C1[H]
[H]N([H])C(=O)C1=C2C(=O)N(C([H])([H])C3([H])C([H])([H])C([H])([H])N([H])C([H])([H])C3([H])[H])C([H])([H])C2=C([H])C([H])=C1[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)C1=C(C(=O)C2=C([H])C([H])=C([H])C([H])=C2N1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C(Cl)C2=C(N=C1[H])N(N=C2C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(ON=C1C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C(N=C(S1)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])[C@]1([H])O[H])C1=C([H])C([H])=C(Cl)C(=C1[H])C([H])([H])C1=NC([H])=C(C([H])=N1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C([H])C(N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)S\C(=C(\[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2[H])C1=O
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C([H])([H])C([H])([H])C([H])([H])C3=C([H])N([H])C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C(\Cl)=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC(=O)C4=C([H])C(Cl)=C(N([H])[H])C([H])=C4OC([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C(C2=C([H])C(Cl)=C([H])C([H])=C2N1[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N([H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(F)=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C(Cl)N=C23)N([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])OC([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1[C@@]2([H])C3=C(N(C4=C([H])C([H])=C(C([H])=C34)S(=O)(=O)C3=C([H])C4=C(C([H])=C3[H])N(C([H])=C4[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
CCN1CCN(CC1)C(=NO)C1=CN=CC(=C1)C#C[C@]1(CN2CC3=C(C=C(OC)C=C3)C2=O)NC(=O)NC1=O
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@]2(O[H])C(=O)C([H])([H])SC2=NC3=C([H])C([H])=C([H])C([H])=C3N=C2[H])[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C(=O)C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]12[H]
[H]N1N=NC(=N1)C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C(OC([H])([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])C([H])=C2[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C([H])N=C([H])C([H])=N1)C1=C([H])C(=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2N=C(N([H])C2=NC([H])=C1Br)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])N1N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C([H])C(=C([H])C([H])=C2N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]1(ON2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])C2=C([H])C(=C([H])C([H])=C2S1)C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C(N([H])C3=C2C([H])=C(S3)C(C(=O)N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N1C([H])([H])C2=C([H])C([H])=C(C([H])=C2C1([H])[H])[C@@]([H])(N1C([H])([H])[C@]([H])(N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]OC1=NSC(N([H])C2=C([H])C([H])=C(OC3=C([H])C(Cl)=C([H])C([H])=C3Cl)C([H])=C2[H])=C1\C(=N\C([H])([H])C([H])([H])[C@@]([H])(O[H])C([H])([H])O[H])N([H])[H]
[H]N([H])C1=NC(C2=C([H])C([H])=C([H])O2)=C2N=C([H])N(C2=N1)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C(=O)O[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(ON=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C2([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=C([H])N=C2N=C(OC2=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O\N=C(\C(=O)N([H])C([H])([H])C([H])([H])S[H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]O\C(OC([H])([H])C([H])([H])[H])=C1\C(=NC(C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C(=O)OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@]1([H])C#CC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(Br)=C2N(C(=NC2=C1Br)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=C([H])N=C(O1)C1=C(C([H])=C([H])C(F)=C1[H])[C@@]1([H])C([H])([H])N2C([H])=C([H])N=C2C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C([H])C([H])=C3S2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]O[C@@]1(C#CC([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])[C@@]3([H])C(=C4C(=C([H])C(=O)C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])[C@@]([H])(C3=C([H])C([H])=C(OC([H])([H])[H])C(=C3[H])C([H])([H])[H])C([H])([H])[C@]12C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])C2=C([H])C([H])=NC([H])=N2)C([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C2C(=O)[C@]([H])(C([H])([H])OC(=O)C3=C(Cl)C(=C([H])C([H])=C3Cl)S(=O)(=O)N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])S(=O)(=O)C2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(N1[H])C([H])([H])[H])C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])([H])[C@]([H])(C(=N1)N([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C(=O)[C@](O1)(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C#N)C([H])=C(C([H])=C2C([H])=C1[H])C1=C(F)C([H])=C(O[H])C([H])=C1F
COCCCN1C(NC(=O)C2=CC=CC(=C2)C#N)=NC2=CC(=CN=C12)C(=O)N1CCOCC1
[H]N(C(=O)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]\C(=C1\C2=C([H])C([H])=C(F)C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC(=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C3=C([H])C([H])=C(S3)C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@](C([H])([H])N([H])C1=C([H])C([H])=C([H])C2=NC([H])=C([H])C([H])=C12)(C([H])([H])C(C1=C(OC([H])([H])[H])C([H])=C([H])C(F)=C1[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC([H])([H])C1=C(N=C(C(=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)[C@]([H])(N([H])[H])C([H])([H])N([H])C(=O)OC([H])([H])C1=C(Br)C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C2C([H])=C([H])C(=O)OC2=C1[H])C(=O)C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])N1C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C(F)C([H])=NC3=C([H])C([H])=C(OC([H])([H])[H])N=C23)C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C1=NC([H])=C2OC([H])([H])C([H])([H])OC2=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)O[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])SC([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CCCS(=O)(=O)N1CCN(CC1)C1(CNC(=O)C2=CC=CC=C2)CCCCC1
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])OC(=O)N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])[C@@]([H])(OC([H])([H])[H])C([H])([H])OC(=O)N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[C@]1([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])[C@]([H])(OS(=O)(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N1C2=C([H])C([H])=C(Cl)C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])SC(=N2)C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])SC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C(N([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C(=O)N([H])[H])C(=O)N([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])N(C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C(C#N)C([H])=C([H])C([H])=C1[H]
NC1=NC(N\N=C\[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)CO)=NC2=C1N=CN2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
[H]O[C@@]1([H])[C@@]([H])(N([H])C(=O)[C@]2([H])N(C(=O)[C@]([H])(N([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=N[H])N([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=NC(=O)N(C([H])=C1F)[C@@]1([H])OC([H])([H])C([H])=C([H])C1=O
CC1=CC(COC2C3CCN(CC3)C2C(C2=CC=CC=C2)C2=CC=CC=C2)=CC(=C1)[Si](C)(C)C
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])[C@]([H])(C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C(C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])O[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=NC2=C([H])C(=C([H])C([H])=C2C(OC([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C(=O)[C@]([H])(N([H])C(=O)[C@]1([H])C([H])=C([H])[C@@]([H])(N2N1C(=O)N(C2=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
O=C(NCC1=CC=CC1[Fe++]C1C=CC=C1)OCCCC1=CNC=N1
[H]\C(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C1/C(=O)C2=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]S\C(=N/N([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N(C(=O)C1=C(Cl)C2=C(N=C1[H])N(N=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(=C1[H])C(F)(F)F
[H]OC(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N2N=NC(=N2)C2=C([H])C(=NC(=C2[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C(=O)N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C#N)C1=C(N=C([H])C([H])=C1[H])C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC(C)N1C=NC2=C(NCC3=C(O)C=CC(Cl)=C3)N=C(NCC(C)(C)O)N=C12
[H]N(C(=O)C1=NSC([H])=C1N([H])C([H])([H])C1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N1C2([H])C3=C(N(C4=C(OC([H])([H])[H])C([H])=C(C([H])=C34)S(=O)(=O)N3C([H])=C([H])C4=C3C([H])=C([N+]#[C-])C([H])=C4[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C2([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C([H])([H])[H]
[H]N1C2=NC(=C([H])C(=C2N=C1C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)N1C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(OC([H])([H])C([H])([H])C([H])([H])[H])N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=NC([H])([H])C1([H])[H])C([H])([H])N1N=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C(=C1[H])C(=O)OC([H])([H])[H]
[H]N(N([H])C(=O)C([H])([H])SC1=NN=C(N1N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C([H])([H])[H])C(=O)C([H])([H])[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]C1=C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])[H])[C@]2([H])C([H])([H])N(C(=O)C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])N([H])C2=C(C([H])=C([H])C(=C2[H])C(=O)N(C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])[H])C([H])([H])N(C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C([H])C(F)=C(C([H])=C2[H])C2=C([H])C3=C(O2)C([H])=C([H])C(OC([H])([H])C2([H])C([H])([H])C2([H])[H])=C3[H])C1([H])[H]
[H]N1C2=C([H])C(=NN2C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(SC([H])([H])[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1C([H])([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C#N)C1=C(N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])N1C(=NC(=C1C(=O)C([H])([H])C([H])([H])N(C(=O)C1=C([H])N=C([H])C([H])=C1[H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
CN1N=C(C2=C1C=C(Cl)C=C2)C1=NC2=C(NC=C2C(=O)NC(C)(C)CO)N=C1
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C([H])=C2N=C(N([H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])=C(C2=C1[H])C([H])([H])[H]
[H]O[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(S1)C([H])([H])N1C2=C(N=C1C(F)(F)F)C([H])=C([H])C([H])=C2[H])[C@@]([H])(O[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C1=C(C([H])=C([H])[N+]([O-])=C1C1=C(F)C([H])=C(OC([H])([H])[H])C([H])=C1F)C(=O)C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]OC1=C(C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=NC2=C([H])C(=C([H])C([H])=C2N1[H])C(=N[H])N([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@]1([H])N([H])C(=O)N(C1=O)C([H])([H])C(=O)N([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([O-])=O)C([H])([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]N(C1=NC(=O)C(O1)(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]N([H])C1=NC(=C(S1)[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C(O[H])C([H])=C(C([H])=C2S1)C([H])([H])N1C([H])=NC([H])=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2N1S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H]
[H]C1=C([H])C(=C(C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=NN=NN1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])Br
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])N(N=C1[H])C([H])([H])C1=NOC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)S(=O)(=O)C1(F)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C2=C(N([H])N=C2[H])C([H])=C1[H]
[H]N([H])C1=C2C(OC(=C2C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C(F)C([H])=C([H])C(=C3[H])C(F)(F)F)C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=NC([H])=N1
[H]N(C(=O)C1=C([H])SC([H])=C1[H])C1=NC(=C(S1)C(=O)N([H])C1=C(Cl)C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2OC1=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C1=C(N([H])C(=O)N([H])[C@@]2([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C4C([H])=C(F)C([H])=C([H])C4=C3[H])C([H])([H])C2([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(N([H])C([H])([H])C2=NC([H])=C([H])C([H])=C2[H])=C(C([H])=C1[N+]([O-])=O)[N+]([O-])=O)C([H])([H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C(O1)C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(O[H])N=C2C([H])=C(C(=NC2=N1)[N+]([O-])=O)[N+]([O-])=O
[H]N(N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C(=O)OC1=C([H])C([H])=C(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C1=C([H])N=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O
[H]N1[C@@]2([H])C(C(=O)N(C([H])([H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])C3([H])C([H])([H])C3([H])[H])=C(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C4=C(OC([H])([H])[H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])[C@]1([H])C([H])([H])N(C(=O)C([H])([H])[H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1(C#N)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])C([H])([H])[C@@]1([H])C(=O)O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])OC(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C2OC(F)(F)OC2=C1[H]
[H]N1C2=C([H])C(=C([H])C([H])=C2N=C(C2=C([H])C([H])=C([H])C(C#N)=C2[H])C([H])([H])C1=O)C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C(N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]O[C@]12C(=O)O[C@]([H])(C([H])([H])[H])[C@@]1([H])[C@@]([H])(C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])SC([H])=C1[H])[C@]([H])(C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])[C@]1([H])[C@]2([H])O[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H]
C[C@H](CN)N1C=CC2=C(C=CC(C)=C2NC(=O)CC2=CC=C(C(F)=C2)C(F)(F)F)C1=O
[H]N(C1=NC(=NN(C1=O)[C@]([H])(C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C(=C(OC([H])([H])[H])N=C1C([H])([H])[H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C2=C1C([H])([H])C1=C2C([H])=C(C(Cl)=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C(O1)C(=O)OC1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C(=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@]1([H])C([H])([H])O[C@@]([H])(O[C@]1([H])C1=C(O[H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H])\C1=C([H])N=C([H])C([H])=C1[H]
[H]OC1=NC([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])([N+]([H])([H])[H])[C@@]([H])(O[H])C([H])([H])C(\[H])=C(/[H])[C@@]([H])(O[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)OC([H])([H])C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])([H])C([H])=C([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])N2C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]2([H])C2=C(C3=C(N2[H])C([H])=C([H])C([H])=C3[H])C1([H])[H])[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C#N)C([H])=C1C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(N([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)O[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(\C(=C1/C(=O)N([H])C2=C([H])C(=C([H])C([H])=C12)C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=C(\C([H])=C(/[H])C2=C([H])C([H])=[N+](C([H])=C2[H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C2=NN=C(O2)C([H])([H])[H])C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=C(S1)C1(C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN([H])C2=C1C([H])=C(N([H])C([H])([H])C([H])([H])[H])C([H])=C2[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(=C([H])S1)[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
CC(C)(N)C(=O)N[C@@H](CC1=CC=C(Cl)C=C1)C(=O)N1CCC[C@H]1C1=NC2=C(N1)C=C(Cl)C(Cl)=C2
[H]N(C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C(Cl)C([H])=C1C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C([H])C([H])=N1)C([H])([H])[C@]1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[C@@]1([H])[18F]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(OC([H])([H])[H])C(=O)O[H]
[H]N([H])C1=NC([H])=C2C([H])=C(C(=NC2=C1[H])N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]C1=NC(=C([H])C([H])=C1[H])C1=NN(N=N1)C1=C([H])C([H])=C([H])C(=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(Cl)=C2C(=O)N(C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]OC([H])([H])[C@@]1([H])C2=C(OC(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C1=C([H])C(N([H])S(=O)(=O)C(F)(F)F)=C([H])C([H])=C1OC([H])([H])[H])C([H])=C([H])C(\C([H])=C(/[H])C1=NC3=C([H])C(=C([H])C([H])=C3C([H])=C1[H])C([H])([H])[H])=C2[H]
[H]N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=NC(O[C@@]([H])(C3=C([H])C(Cl)=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(Cl)C([H])=C(OC([H])([H])[H])C(=C1[H])C1=NC(=NN1C([H])([H])[H])N(OC([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C3N(C(=NC3=C([H])N=C12)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C2OC([H])([H])C([H])([H])OC2=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])[C@]2([H])N([H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])OC2([H])[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C(=N1)C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(OC([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC(=O)C1=C([H])C2=C(C([H])=C1[H])N1C(=C(C(=O)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(F)(F)F
[H]N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])N1C(SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=NN=C1C1=C([H])C([H])=C([H])C([H])=N1
[H]OC(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])OC1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)C(=O)C1=C([H])C([H])=C([H])S1
[H]N(C([H])([H])C1=C([H])C([H])=C(O1)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C(N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H])=C(C#N)C#N
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C(N=C1[H])C1=C([H])OC([H])=C1[H])C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C(F)=C2[H]
[H]N(C1=NN(C2=C1C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C(F)(F)F)C([H])([H])C(=O)N([H])C1([H])C([H])([H])N(C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2C2=C1C([H])=NC([H])([H])C2([H])[H]
[H]\C(I)=C(\[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1C#N
[H]N(C(=O)[C@@]1([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])S2)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])[C@]1([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
CC(C)(C)C1=CC=C(CC(=O)N2CCC3(CC2)CCN(CNC(=O)C2=CN=CC=C2)C2=C(O3)C=CC=C2)C=C1
[H]C1=C([H])C2=C(C([H])=C1OC([H])([H])[H])C(=O)C1=C(C([H])=C(C([H])=C1[H])C1=NN=C(O1)C([H])([H])[H])S2(=O)=O
[H]OC(=O)C1=C([H])C([H])=C([H])C(OC2=C([H])C([H])=C(C(N([H])C(=O)C([H])([H])O[C@]3([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C2[H])[N+]([O-])=O)=C1[H]
[H]N1C(=C([H])C2=C1C([H])([H])C(N([H])C2=O)(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C(=O)C1=C2N=C([H])N([H])C2=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C1=NN2C(=NC([H])=C2C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]2([H])N([H])C([H])([H])[C@]([H])(F)C2([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
CNC(=O)C1=CC(=CC=C1)N1CCN(CC1)C1=NC=C(S1)C(O)(C(F)(F)F)C(F)(F)F
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])=NC([H])=C2[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])SC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
CCN1CCC(CC1)NC1=CC2=C(NC(=O)C2=C(C2=NC3=CC(OC)=CC=C3N2)C2=CC=CC=C2)C=C1
[H]OC([H])([H])[C@@](N([H])[H])(C([H])([H])OP(=O)(O[H])O[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1Cl)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C(N=NN1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N
[H]N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\[H])C3=C(C4=C(N3[H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C2=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)[C@]2([H])C([H])=C([H])C([H])([H])N3N2C(=O)N(C3=O)[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])SC2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C(=O)N(C2=C(\C([H])=C(/[H])C(=O)N([H])S(=O)(=O)C3=C([H])C(F)=C(F)C([H])=C3[H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]OC1=C(\C([H])=C(/[H])C([H])([H])C([H])([H])[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])N([H])[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(=O)C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C2=C(N([H])C3=C2C([H])=C(C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(=O)OC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=NC([H])=C1Cl
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])N(N=C1[H])C([H])([H])C1=C([H])C([H])=C(N=[N+]=[N-])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])OC1=NC([H])=NC(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC(=C([H])N2C1=NC([H])=C2C1=C([H])N([H])N=C1[H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N2C(=O)N([H])C(=C(C(=O)OC([H])([H])[H])[C@]2([H])C2=C(F)C([H])=C(F)C(F)=C2[H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(OC(=O)N2C([H])([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C2=NC([H])=C([H])N2C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NN([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2=C(F)C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=N1)[C@]([H])(C([O-])=O)C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N1C(=O)C([H])([H])C([H])([H])C2=C1N=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C(F)C(Cl)=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N([H])C(=O)C2=C([H])C(=O)C3=C([H])C([H])=C(F)C([H])=C3O2)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(OC([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C2([H])[H]
[H]C1=C(N=C2C([H])=C([H])C(=C([H])N12)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(Cl)=C3Cl)C([H])([H])C2([H])[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])N(C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C(F)(F)F)C(F)(F)F
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])[C@@]1([H])C(=O)N([H])C([H])([H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(C#CC2=C([H])N=C3C([H])=C([H])C([H])=C([H])N23)=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(F)(F)F
[H]OC(=O)[C@]1([H])N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C2C([H])=C(C([H])=C([H])C2=NN1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C1=NOC(=N1)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N([H])C(=O)C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])C([H])=C(OC2=C([H])C(=C(Cl)C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C(C#N)C(=N1)N([H])[H])[C@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C(=O)OC1(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N1C([H])([H])C(=C([H])C([H])([H])C1([H])[H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)S(=O)(=O)C1=C(N=C(O1)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])N=C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]C1=C2C(=C([H])C(OC([H])([H])[H])=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N=C1N2N=C(SC2=NC(=O)\C1=C(/[H])C1=C([H])C(OC([H])([H])[H])=C(OS(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N=C(SC([H])([H])C(=O)N2C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])N=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N=C(S1)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]22[C@]3([H])N([H])[C@@]([H])(C4=C([H])C([H])=C([H])C([H])=C4[H])[C@]4(C([H])([H])[H])C([H])([H])[C@@]12C([H])=C([H])[C@]34OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(OS(=O)(=O)C(F)(F)F)C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C(C#N)C([H])=N1)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(OC1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C([H])C(=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C(SC([H])([H])[H])C(=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])OC2=C3N=C(C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=N1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N/C([H])([H])[H])\N([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)N([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])[C@@]([H])(C(=O)N([H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=NC(=C([H])C([H])=C2C(=C1[H])C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C(N4C([H])=C(Cl)C([H])=C([H])C4=N3)C([H])([H])C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])C1=C2OC(=C([H])C(=O)C2=C([H])C([H])=C1OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(O1)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(N([H])C2=C([H])N=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])=C1[H])C([H])=O
[H]O[C@@]([H])(C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])N([H])C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=NC2=C1C([H])=C(N2C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])=NC2=C1C([H])=NC([H])=C2[H])C1=C(Cl)C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C2=C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C4=NC(F)=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])N=C([H])N=C2N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C2C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C2C(=C1[H])[C@]([H])(N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N1N(C(=O)C(=C1C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])[N+]([O-])=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])S1)C1=C([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2N=C1[H]
[H]OC([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C3=C([H])C(OC([H])([H])C4=NOC(=N4)C4=C(F)C([H])=C([H])C([H])=C4[H])=C([H])C([H])=C3C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(N2SC3=C(C([H])=C([H])C(F)=C3[H])C2=O)=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C2N=C(N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C(C([H])=C([H])C(OC([H])([H])[H])=C1[H])[C@@]1([H])N(C2=NN([H])N=N2)[C@@]([H])(C2=C1C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C1C1=C([H])C([H])=C(OC([H])([H])[H])C(F)=C1C([H])([H])S2)C([H])(F)F
[H]N(C(=O)C1=C(N([H])C2=NN([H])C([H])=C2[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C(OC([H])([H])C2=NC(=NO2)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C([H])N=C2[H])C([H])=C([H])C([H])=C1[H]
[H]\C(C1=C([H])C([H])=C(Cl)S1)=C1\C([H])([H])N2[C@]3([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]1([H])C3([H])[H]
[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(ON=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])N([H])C(=O)C([H])([H])C1=C([H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N1C(=O)[C@@]([H])(N2C(=O)OC([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1F)C(F)(F)F
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C([H])C([H])=C3[H])[C@]2([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@@]([H])(C(\[H])=C(/[H])C2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(O[H])C(=C1[H])C1=C([H])C([H])=C(O1)C(\[H])=C1/SC(=O)N([H])C1=O
[H]N(N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C([H])([H])N1C(=O)[C@]([H])(OC2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1C([H])([H])[H])C1=C(C#N)C([H])=NC2=C([H])C(\C([H])=C(/[H])C3=C([H])C([H])=NC([H])=C3[H])=C([H])C([H])=C12
[H]N(C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])N(C1=C2C2=C(C(=O)N([H])C2([H])[H])C2=C1C([H])([H])C([H])([H])C1=NN(C([H])=C21)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])\N=C(N([H])[H])/N([H])C(=O)[C@]([H])(N([H])[H])[C@]2(SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]ON([H])C(=O)C1=C(N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])C(=C([H])C(Br)=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(C1=C([H])C([H])=C([H])C(F)=C1C([H])([H])[H])(C1=C(C(F)=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[N+]2(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=NC(=C([H])S1)C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(=C([H])C(=O)O2)C(F)(F)F)C([H])([H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1(C(=O)N([H])C([H])([H])C(F)(F)F)C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])N(N=N1)C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C(F)=C(C([H])=C2[H])C2=C([H])C(=NO2)C([H])([H])[H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C(N([H])[H])=C2N=C([H])C([H])=C([H])C2=C1[N+]([O-])=O
[H]\C(=C(\[H])[C@@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C(C(=O)SC([H])([H])C([H])([H])[H])C(=C1C(=O)OC([H])([H])C([H])([H])F)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1N=C([H])N=C1[H]
[H]N([H])C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OS(=O)(=O)O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(\[H])=C(\C1=C([H])C2=C(SC([H])=C2C2=C([H])C(=C([H])C(=C2OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C1=C(N=C(C(=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)[C@@]([H])(C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C(=O)OC([H])([H])[H])C([H])=C2C([H])=C1[H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2C([H])=C(C#CC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])N([H])[H])C([H])=C([H])C2=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])[H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])[H]
[H]N(C(=O)C1=NC(=C([H])C([H])=C1[H])N1C([H])=C([H])C2=C1N=C(N=C2[H])N([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(\[H])=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C#CC([H])([H])OC1=NC(=NC(N([H])S(=O)(=O)C2=NC([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1OC1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(OC(=O)C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C1=C([H])N=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C2=NC(=NC(=C2C([H])([H])O[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C2C([H])=C([H])C(=NN2N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C2=C3N(C(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C3=C1[H]
[H]N([H])C1=NON=C1C1=NC2=C([H])N=C([H])C(C(=O)N3C([H])([H])C([H])([H])[C@@]([H])(N([H])[H])C3([H])[H])=C2N1C([H])([H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])N([H])[C@@]1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
CCCCCN1C=C(C(=O)NC23CC4CC(CC(C4)C2)C3)C(=O)N2N=CN=C12
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)O[C@]([H])(C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C2=C([H])C(Br)=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H]
[H]OC1=C2C(N([H])C([H])=C2C([H])([H])C([H])([H])N2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C2=C(N([H])C([H])=C2C2=NC3=C(C#N)C([H])=NN3C(N([H])C3([H])C([H])([H])C3([H])[H])=C2[H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])[C@]([H])(C([H])=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(N([H])C(=O)N(C2=NC([H])=NC(N([H])C3=C([H])C([H])=C(C([H])=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C2[H])C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N([H])C1=C([H])C2=C(C([H])=C1Cl)C(=O)N([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C(O[C@]([H])(C3=C([H])C(F)=C([H])C([H])=C3[H])C([H])([H])[H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@]2(O[H])C(=O)C([H])([H])SC2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])C([H])=C([H])[H])[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C4=C(C([H])=NN4C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]12[H]
[H]N([H])C1=C([H])C(=NC2=C(Br)C([H])=NN12)[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N2N=C(C([H])=C2N=C1[H])C([H])([H])[H])C(F)(F)F)C([H])([H])C(N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])[C@@]([H])([C@]1([H])N([H])C(=O)C1=C(SC([H])=C1[H])C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C(Cl)C([H])=C([H])C(OC([H])([H])C([H])([H])N([H])C([H])([H])C2=C([H])C([H])=C([H])S2)=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C1=C([H])C(=NC([H])=C1[H])N1C([H])([H])C([H])([H])C(C(=O)N2C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])\N=C(/S[H])N([H])C2=C([H])C([H])=C(F)C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N1C(=O)C2=C(C([H])=C(C([H])=C2[H])C2=C([H])N(N=C2C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(C#CC2=C([H])N=C3C([H])=C([H])C([H])=C([H])N23)=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]C1=NC2=C(C([H])=C1[H])C([H])=C([H])C([H])=C2S(=O)(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]1([H])N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[C@@]([H])(N2C(=O)N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C(=O)OC3=C([H])C([H])=C(C([H])=C23)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(C3=C([H])C([H])=C(O[H])C([H])=C3O[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])O2
[H]N([H])C1=C([H])C(=NC(OC([H])([H])C([H])([H])[H])=C1C#N)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C2N(C([H])=C(C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C(=O)N([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(F)(F)F
[H]C1=C(C([H])=C(Br)C(=C1[H])N1C(OC([H])([H])C2([H])C([H])([H])C2([H])[H])=NC2=C1N=C(N=C2N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C2=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C1C(=O)N2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C(=O)OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H]
[H]N=C(N([H])[H])N([H])OC([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(Cl)=C1[H])C(=O)N(C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NN2C(=N1)C([H])=C([H])C([H])=C2C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H]
[H]C1=C(C2=NC(=NO2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(SC2=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(=C2C(F)(F)F)C(F)(F)F)=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=NC2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2N1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(SC(=C2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])OC2=C(Br)C([H])=C(Br)C([H])=C2[H])=C1[H]
[H]OC(=O)[C@]([H])(SC1=NC(N([H])C2=C([H])C(OC([H])([H])C(F)(F)F)=C([H])C(OC([H])([H])C(F)(F)F)=C2[H])=C([H])C(Cl)=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2C(OC3(C([H])([H])C2=O)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C3([H])[H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC1=C([H])C([H])=C(Cl)C(=C1[H])C([H])([H])N1C2=NC(OC([H])([H])[H])=C([H])C([H])=C2C(C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(\C([H])=N\N=C(/S[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C2C(=C1O[H])C1=C(O[H])C3=C(C(=O)C4=C(C([H])=C(O[H])C(=C4O[H])C([H])([H])[H])C3=O)C(OC([H])([H])[H])=C1C([H])([H])C2([H])[H]
[H]N1N=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C2=NN=C(N2C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C3=C1C([H])=C([H])C([H])=C3[H])C(=O)N([H])[H])C([H])([H])[C@@]([H])(N([H])C(=N[H])N([H])[H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(Cl)=C(N([H])C(=O)C2=C(F)C(F)=C(F)C(F)=C2F)C([H])=C1[H]
[H]N1C(=C([H])C2=C1[C@@]1(C([H])([H])N([H])C2=O)C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC(=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])N=C1[H]
[H]O[C@@](C1=C([H])C(Cl)=C([H])C([H])=C1[H])(C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])[H])[C@@]1([H])C([H])([H])N(C(=O)N([H])[C@]([H])(C([H])([H])N([H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(C([H])=N1)C(=C(C(=O)C([H])([H])[H])C(=O)N2C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=NC([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=NC2=C1N=C(SC1=C(I)C([H])=C([H])C(OC([H])([H])[H])=C1[H])N2C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(\[H])C1=C([H])N(N=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N2C([H])=NN=C12)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(=O)(=O)N1C([H])([H])[C@]2(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])O2)C([H])([H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC([H])=NC2=C1C(=C([H])S2)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)[C@@]1([H])C([H])([H])[C@]11C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])N1C(=O)N(C(=O)N([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C2=C([H])C(Cl)=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])OC(=O)C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])=NC2=C1N=C(N([H])C2=O)N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C([H])C(=C([H])C([H])=C12)N1C([H])=NN=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C(=O)N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N([H])C(=O)C2=C(Cl)C(=C([H])S2)C([H])([H])S(=O)(=O)C([H])([H])[H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])[C@@]1([H])N(C(=O)C2=C(C([H])=C([H])C([H])=C2[H])N2N=C(C([H])=C2C([H])([H])[H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(=N1)N([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1Cl
[H]OC(=O)C1=C([H])C([H])=C([H])C(O[H])=C1OC1=C(C(F)=C([H])C([H])=C1[H])C([H])([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])O[C@]1([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])=C([H])N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N([C@]1([H])C(=O)N(C2=C(F)C3=C(C([H])=C2[H])C([H])([H])N([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)S1
[H]OC1=NC([H])=C([H])N1[C@]([H])(C([H])([H])[H])[C@@]([H])(C1=C([H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C2N([H])C(=NC2=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=N2)C([H])([H])C1=C([H])C([H])=C([H])S1)C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
CN1C=C(C=N1)C1=CC(F)=C(CN2C(=O)C(O)(C3=CC=CC=C23)C(F)(F)F)C=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)O[C@]([H])(C([H])([H])[H])C1([H])[H]
[H][C@@]1(CCCCN1)[C@H](C(N)=O)C1=CC=CC=C1
[H]OC(=O)C([H])([H])N1C(=O)N(C2=C([H])N=C([H])C([H])=C2C1=O)C([H])([H])C1=C([H])N(C2=C1C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])[N+]([O-])=C([H])C(=C1[H])C(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C(C([H])=C(Br)C([H])=N2)C([H])([H])C([H])([H])C2=C1C([H])=C([H])C(Cl)=C2[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C2N(C(=O)N(C2=N1)C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(N([H])C([H])([H])P(=O)(O[H])O[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC(F)=C(C([H])=C1[H])C1=C([H])N=C2N=C(SC2=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC2=NC([H])=C([H])C([H])=C2C2=NC(=NC([H])=C2[H])N([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
CN1C=CC2=C1C(OC1=CC=C(NC(=O)NC3=CC=NC=C3)C(Cl)=C1)=NC=N2
[H]N(C([H])([H])C1=C(N=C(O1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(C#CC2=C([H])N=C3C([H])=C([H])C([H])=C([H])N23)=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]O[C@]1([H])C([H])([H])O[C@@]([H])(N2C([H])=C(C3=C2C([H])=C([H])C([H])=C3Cl)C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])[C@]([H])(O[H])[C@@]1([H])O[H]
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])O[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])[C@@]([H])(F)C1([H])[H])C(F)(F)F
COC1=NC(=NC(C)=C1F)N1C[C@H]2C(=O)N(C)C(=N)N[C@]2(C1)C1=CC=CC=C1F
[H]\C(=C(\[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1Cl)C(=O)C1=C(OC([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC(=O)[C@@]([H])(N([H])[H])C1=C(N(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)N(C2=C(C(=C([H])C(OC([H])([H])[H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2F)C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C([H])([H])[C@@]1([H])S[C@@]([H])(N(C1=O)C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])N([H])[C@@]([H])(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C2=NC3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N3[H])=C1[H]
[H]N(C(=O)C1=NC(=NC([H])=C1Cl)S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=NN=C(SC([H])([H])[H])S1
[H]N([H])C([H])([H])C1=NOC(=N1)C1=C2C([H])=C([H])C([H])=C([H])C2=NN1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])C(=O)[C@]4(C([H])([H])C5=C(C([H])=C([H])C([H])=C5[H])C4([H])[H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]N1C2=C(N=C1[C@@]1([H])N(C3=NC([H])=NC(=C3[H])N3C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])=C(Cl)C(Cl)=C2[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)N([H])C([H])([H])C1=O)C([H])([H])O[H]
[H]OC(=O)C1=C([H])C(Br)=C([H])C2=C1OC(=C([H])C2=O)C1=C([H])C([H])=C([H])C(OC([H])([H])C2=NC3=C(C([H])=C([H])C(Cl)=C3[H])C([H])=C2[H])=C1[H]
[H]OC(=O)C1=C([H])C2=C(OC3=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC4=C(C([H])=C(C(O[H])=C4[H])C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])C([H])([H])[H])=C3C([H])([H])C([H])([H])C(=O)O[H])C2=O)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])[H]
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])[C@@]2([H])N([H])C([H])([H])[C@]1([H])C2([H])[H])C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(=O)N([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)N([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC2=NC([H])=NC(N3C([H])([H])C([H])([H])N(C(=O)OC4=C([H])C([H])=C([H])C5=C4C([H])=C([H])C([H])=C5[H])C([H])([H])C3([H])[H])=C12)C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[C@]([H])(C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C(C(=O)N1C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])/C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C\2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]O[C@](C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1Cl)N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C(F)(F)F
[H]N1C(=O)N([H])[C@](C1=O)(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])S1(=O)=O
[H]OC(=O)C1=C([H])C([H])=C(O[H])C(=C1[H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])=C1[H]
[H]N=C(N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C([H])S1
[H]N(C1=NN2C(=NC(=C2C([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2N(C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@]([H])(C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C3C(=N2)N([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(N=N1)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)S(=O)(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C1=NC(=NC(=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C(N(N=C1C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C2(OC([H])([H])C3=C4C([H])=C([H])C([H])=C([H])C4=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]\C(=C(/[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])OC([H])=C1[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H][C@]12CC3=C(C(OC)=CC=C3)[C@@]3(CCN1CC=C)CC(=O)CC[C@@]23[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])SC([H])([H])[C@]2([H])N([H])C(=O)N([H])[C@]12[H])C([H])([H])[H]
FC1=CC(F)=C(NC2=CC3=C(C=C2)C(=O)C2=C(CC3)C=CC(OCCN3CCOCC3)=C2)C=C1NC(=O)C1CCOC1
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])[H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]2(C([H])=C([H])C3=C2C([H])=C([H])C([H])=C3[H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C(C2=C([H])C([H])=C(F)C([H])=C2S1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2N=C(C3=C2C([H])([H])C([H])([H])N(C3([H])[H])S(=O)(=O)C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1F)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1(F)C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]S\C(=N\C([H])([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N1C(=NC2=C1N([H])C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(O[H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C1N(N=C(N([H])[H])\C1=N/N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2C(SC3=C2C([H])=C([H])N(C3=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=NC([H])=C1[H]
[H]N([H])C(=O)C1=C(N([H])C2=C3C([H])=C([H])N([H])C3=NC(=N2)N([H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])S1
[H]N1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C([H])=N3)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C(=N[C@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C(F)=C2[H])C1=O)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)C([H])([H])SC1=NC(=O)C([H])=C(N1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(N=C2[H])N2C([H])([H])[C@]3([H])N(C(=O)OC([H])([H])C4=C([H])C([H])=C([H])N=C4[H])C([H])([H])[C@@]2([H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C#N)C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(OC([H])([H])C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]O[C@](C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H])(C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[N+]1=C(C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=NC(=C(N2C([H])=C1[H])C1=C([H])C(=NC([H])=C1[H])N([H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C2=C(S1)N1C(=NC([H])=C1C([H])([H])[H])C(=N2)N([H])C([H])([H])[H]
COC1=C(OC)C=C(CCOC(=O)C2=C(CCN(C)C2)C2=CC=CC=C2)C=C1
[H]OC(=O)C([H])([H])C([H])([H])[C@]1(C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])N(C(=O)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]C1=C(OC2=C1C([H])=C(C([H])=C2[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
COC1=CC=CC(=C1)C1=C2C=CC=CC2=C(NC2=CC=CC(=C2)S(N)(=O)=O)N=N1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2S1(=O)=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C2C(SC([H])=C2C(=O)OC([H])([H])C([H])([H])[H])=C1[H])C1=NC([H])=NC2=C1C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C2[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]N1N=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C1C(=O)N(C2=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(=C2[H])C([H])([H])[H]
[H]N1C(=NC2=C(C([H])=C(C([H])=C12)C(F)(F)F)C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C1=NC(N([H])C([H])([H])C(F)(F)F)=C([H])C2=C1C(=O)N([H])C([H])=C2[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(SC([H])([H])[C@]2([H])OC(=O)[C@](C(=O)OC([H])([H])C([H])([H])[H])(C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]S\C(=N/C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H])N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C(N=C([H])N1C([H])([H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OP(=O)(O[H])C([H])([H])N([H])[C@]([H])(C1=NN([H])N=N1)C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]OC(=O)C(\[H])=N\O[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])C2=NC3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])[H])C(=O)N([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])SSC1([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=C([H])N=C1N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1=NC2=C(N1[H])C([H])=C(Cl)C(Cl)=C2[H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C(=O)N([H])[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])P([O-])(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C([O-])=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C(C([H])=C(C3=C([H])C([H])=C([H])C(=C3[H])[C@@]([H])(N(C(=O)C3=C([H])C([H])=C(F)C([H])=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C2=N1)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C3=C(C([H])=C([H])C2=N1)N(C(=C3[H])C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])N([H])C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C2N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C13)C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(SC(=C2C2=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=NN(C(=O)N12)C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C(Cl)C(=C(Cl)C([H])=C2[H])C([H])([H])OC2=C3N=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])[C@]1([H])OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]1([H])OC1=C(F)C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[C@]1([H])OC2(O[C@@]1([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])=C([H])C(=O)C([H])=C2[H]
[H]N(C1=NC(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C2N(C(=C(C2=C1[H])C([H])([H])C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(N([H])C3=C2C([H])([H])C([H])([H])N2C([H])([H])[C@]4([H])C([H])([H])[C@@]3([H])[C@@]2([H])[C@]([H])(C([H])([H])C([H])([H])[H])C4([H])[H])C([H])=C1[H]
[H]N(C(=O)C1(N([H])C(=O)C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)C1=NN=C(O1)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C(=O)SC3=C([H])C([H])=C(Cl)C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]C1=C([H])C2=C(N=C(S2)C(=O)C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C(F)C([H])=C2[H])C1=C([H])C([H])([H])N(C([H])([H])[C@]([H])(C2=C([H])OC3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C([H])=C(C([H])=C([H])C2=C([H])C([H])=N1)C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(ON=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=NO[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C1([H])[H]
[H]C#C[C@]1([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C#N)C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(C1=NC2=C(C([H])=C([H])N2C2=C([H])C([H])=C([H])C([H])=N2)C([H])=N1)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)C([H])=C(C2=C1C([H])=C([H])C1=C2C(=O)OC2=C1C(=C([H])C([H])=C2[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@](OC1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])[C@]([H])(OC1=NC(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=N1)C(=O)OC([H])([H])[H]
[H]OC(=O)[C@]([H])(C([H])([H])C1=C([H])C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C(C#N)C([H])=NC2=C1SC(=C2[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@]([H])(O[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CN1N=C(C)C(C(=O)N2CCCCC2C2=CC=CN=C2)=C1OC1=CC=CC(Cl)=C1
[H]N1N=C([H])C2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C([H])N=C12)C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(F)C([H])=C2N(C(=O)N([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C(=O)N(C2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])C1=C([H])C2=C(C([H])=C1[H])C(=C([H])N2[H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]N1C2=C(N=C1C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N2[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NN(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C12)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)S1
[H]OC([H])([H])[C@@]([H])(O[H])[C@@]([H])(C([H])([H])O[H])C([H])([H])N([H])C([H])([H])C1=C([H])N([H])C2=C1N=C([H])N([H])C2=O
[H]ON1C(=O)[C@]([H])(N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(S2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])=C([H])C1([H])[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)C1([H])C2=C(OC3=C1C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(Br)=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])=NC([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C(Cl)C([H])=C1Cl)C(=O)N([H])C1=C([H])C([H])=C(OC2=NC3=C(O2)C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C3=C([H])C(=C([H])C([H])=C3SC3=C2C([H])=C([H])C([H])=C3[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]([H])(N1C(=O)[C@@]([H])(N2C(=O)OC([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C(\[H])=C(/[H])C1=C([H])C(I)=C([H])C([H])=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(Cl)=C(C(N([H])C(=O)C2=NC3=C(S2)C([H])([H])N(C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])N(C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C(=O)[C@@]1([H])C2=C(C3=C([H])C(Cl)=C([H])C([H])=C3N2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])N2C(=NO[C@]2([H])C2=C([H])N=C([H])C([H])=C2[H])C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(N1C([H])([H])[C@]([H])(N(C([H])([H])C([H])=C([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
COC1OC2=C(C3=C(C(O)=C2)[C@@]2(C)C(O3)=CC(O)=C(C(C)=O)C2=O)C(=O)N1C(=O)NCC1=CC=CC=C1N(O)=O
[H]N(C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1=C(C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=NN=C(O1)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C2(OC3=C([H])C([H])=C(F)C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(=O)N(C2=C1C([H])=NN2C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C1=C(N([H])C(=N1)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(N2C(=C(C3=C2C([H])([H])C([H])([H])N(C3=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(Cl)=C1[H]
[H]N(C(=O)OC1=C([H])C([H])=C2N(C([H])([H])[H])[C@@]3([H])ON(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3(C2=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1[C@]2([H])C3=C(N(C4=C(C([H])=C(C([H])=C34)S(=O)(=O)C3=C([H])N=C([H])N=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C2=C1N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=NOC(=C1[H])C1=C([H])C([H])=C(Cl)S1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
Cc1cnc(Nc2c(Cl)cccc2Cl)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC(=C(C3=C([H])OC([H])=C3[H])C(=O)N2C([H])([H])C2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(N(C(=C1[H])C([H])([H])C([H])([H])C(=O)N(C1=C([H])C([H])=C(Cl)C(=C1Cl)C([H])([H])OC1=C2N=C(C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C(Cl)N=C1[H]
[H]C1=C(N2N=NC3=C(N=C(N=C23)C([H])([H])[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(Br)=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])[C@]([H])(C#CC1=C([H])N=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S1)C([H])([H])[H]
[H]N(C(=O)C1=C(N([H])C(=O)C2=C(Cl)C3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C(=O)C2=C(C1=O)C1=C(C3=C2C2=C([H])C(=C([H])C([H])=C2N3[H])C(=O)C([H])([H])N2N=C([H])N=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=NC2=C1C([H])=NN2C([H])([H])C([H])([H])[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1=NC([H])=C2N1C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1N=C2N([H])C1=C(Cl)C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(C2=C([H])C([H])=C([H])O2)=C(C([H])=C1[H])C1=NC([H])=NC([H])=C1[H]
[H]N(C1=NC([H])=C([H])C(=C1[H])C1=NN(C(=O)N1C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC1=NN=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])S(=O)(=O)C(F)(F)F)C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C2N=C(C([H])=C([H])C2=C1[H])N1C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(N([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C(=C23)C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(=C([H])S1)C1=NC2=C([H])C([H])=C(C([H])=C2S1)C([H])([H])[H]
[H]C1=C(C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C1[H]
[H]O[C@@]1(C(=O)OC([H])([H])C2=C1C([H])=C1N(C2=O)C([H])([H])C2=C(C3=C([H])C(=NC([H])=C3N=C12)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N2C(=O)C([H])([H])N(C(=O)C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])C(=O)C1=NC2=C(S1)C([H])([H])C([H])([H])C2([H])[H]
[H]N1C(SC([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)=NC2=C([H])C(F)=C(C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C#CC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C2=NC3=C(O2)C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C1=NN(C(=C1C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC(Cl)=C1C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C([H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C2C([H])=C(\C([H])=C(/[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])=C([H])C2=NC([H])=C1C#N
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C(Br)C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C2C(N([H])C([H])=C2S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]N1C([H])=C(C([H])=O)C2=C1C1=C(C([H])=C2[H])C2=C(N1[H])C([H])=C([H])C(=C2[H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]OP(=O)(O[H])C(F)(F)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])[C@]1([H])C(=O)N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])C([H])([H])[C@@](O[H])(C([H])([H])C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C4[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])S1)C1=NC2=C(N([H])C([H])=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]O\N=C1\C2=C([H])C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C2C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])N1C(=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1F
NC1=C2C(SC=C2C2=CC(NC(=O)CC3=CC=CC=C3)=CC=C2)=C(C=N1)C1=CN=CC=C1
[H]N1C([H])=C([H])N=C1[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(N=C2SC(=NN12)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=NC([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])[C@]([H])(F)[C@@]2([H])OC([H])([H])C(=O)[C@@]12[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=NN([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]([H])(O[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C(=C([H])C2=C1N([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])N1C2=C(C([H])=C(Br)C([H])=C2[H])C([H])([H])N([C@]([H])(C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C(=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])[C@@]([H])([C@]1([H])N([H])C(=O)C1=C([H])SC3=C1C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C3[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C(Cl)C(Cl)=C2C(=O)[C@@](C([H])([H])[H])(C([H])([H])C2=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C(=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]1([H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])([C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])O[H]
[H]OC(=O)C1=C(C(C#N)=C(N1C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=NC2=C1C(=C(N2[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(\N=C2/SC(=NN2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N(C1=C([H])C([H])=C(Cl)C(=C1Cl)C([H])([H])OC1=C2N=C(C([H])=C(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])OC([H])([H])[C@]([H])(OC2=C([H])C([H])=C(OC3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])O1
[H]N([H])C1=C(C(=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])N([H])[H]
[H]OC([H])([H])C(=O)[C@@]1(O[H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])C4=C([H])C5=C(C([H])=NN5C5=C([H])C([H])=C(F)C([H])=C5[H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])[C@@]([H])(O[H])C([H])([H])[C@]12C([H])([H])[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]\C(=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[S@@](=O)C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])O1
[H]N(C(=O)[C@]1([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]C1=NC(=NC(OC([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C1[H])N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])=C(C(=O)N=C1SC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C2=NN=C3SC([H])([H])C(=NN23)C2=C([H])C(OC([H])([H])C3([H])C([H])([H])C3([H])[H])=C(OC([H])(F)F)C([H])=C2[H])C(Cl)=C1[H]
[H]N(C(=O)C1=C([H])C(N([H])C2=C3C([H])=NN(C3=NC([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C([H])=C1[H])C([H])([H])[H])C1=NN(C([H])=C1[H])C([H])([H])C([H])([H])[H]
C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)N2C[C@H](CCCNC(N)=N)NC(=O)[C@@H](CSCC2=O)NC(=O)[C@@H](CC2=CC=C(C=C2)C2=CC=CC=C2)NC(=O)[C@H](CC2=CN=CN2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CC2=CC=CC=C2)NC1=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(N)=O)NC(=O)[C@@H](N)CC1=CC=C(O)C=C1
[H]C1=NN(C(=C1C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(C2=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N([H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(S2)C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=C(C2=C([H])C([H])=C([H])N=C2N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(Cl)=C([H])N=C(N([H])C([H])([H])C(F)(F)C2=NC([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C1=NC([H])=C([H])C([H])=C1N1N=NN=C1[H]
[H]C1=C([H])C2=C(C([H])=C1OC([H])([H])[H])C(=O)C([H])=C(O2)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])O[C@]2(C([H])([H])OC([H])([H])[C@]([H])(C3=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C3[H])C2([H])[H])[C@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(Br)C([H])=C([H])S1)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]N(C(=O)N(N(C(=O)C1=C([H])C(F)=C([H])C(=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C1=NC([H])=C(C([H])=C1F)C(=O)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C#N)C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N1N=C(C2=C(N=NS2)C([H])([H])[H])\C(=C(/[H])C2=C([H])N(C3=C2C(OC([H])([H])C2=C(F)C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C3[H])C([H])([H])[H])C1=O
CN(CC1=CC=C(C=C1)C1=NCCN1)C(=O)COCCN(C)S(=O)(=O)C1=CC=C(Cl)C(C)=C1Cl
[H]N([C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C([H])=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(OC([H])([H])C(=O)N2[H])C([H])=C1[H]
[H]N(C(=O)C1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N=C(S1)\N=C(/[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C(N=C1C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C([H])N=C1[H])C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\[H])C3=C([H])C([H])=C([H])N3[H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N1C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(Cl)C([H])=C2[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])S1)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])N(C3=NC([H])=NC4=C3OC3=C([H])C([H])=C(Cl)C([H])=C43)C([H])([H])[C@@]12[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C2(C3=C([H])C([H])=C(C([H])=C3[H])N3C(=O)C4=C(C(=NN4C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C4[H])C(F)(F)F)C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])N([H])C2=C(C([H])=C([H])C([H])=C2O[H])[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])[C@]([H])(C#CC1=C([H])N=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])S1)C([H])([H])[H]
[H]C1=C([H])C2=C([H])C3=C(C([H])=C2C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C3([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C2=NC(=NC([H])=C2[N+]([O-])=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C(S1)C1=NN(C([H])=C1[H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C2=C1[C@]1([H])N(C2=O)C([H])([H])C([H])([H])C1([H])[H])C1=NN([H])C(=C1[H])C([H])([H])N([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N2C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N(C([H])=O)C2=C([H])C([H])=C([H])C([H])=C12)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])N(C([H])=O)C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C(\[H])=C1\C2=C3OC(=NC3=C([H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])/C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C\1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[S@@](=O)C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C#N)C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C(=O)N([H])[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])N1C(=C(C(=C1C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=NC([H])=NC2=C1C([H])=NN2C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]\C(=N/N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]N(N=C1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C(=O)N([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C(=C([H])C([H])=N1)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=C(C(=O)OC1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C(N([H])C2=C(C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C2=C([H])N=C([H])N12
[H]N([H])C([H])([H])C([H])([H])N([H])C1=NC2=C(SC(=C2[H])C2=C([H])C([H])=C([H])N=C2[H])N2C1=NC([H])=C2C([H])([H])[H]
[H]ON([H])C(=O)[C@@]([H])(SC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]12C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C([H])([H])[H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]S[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
FC1=CC=C(C=C1F)C(=O)CC1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
[H]N(C(=O)C([H])([H])N1C(=O)N2C3=C(N([H])C(=O)C2([H])[H])C([H])=C(C([H])=C13)C([H])([H])[H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])[C@]1(N(C(=O)N([H])C1=O)C([H])([H])[H])C2([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])P(=O)(O[H])O[H])C([H])([H])C1=C(O[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C1=C([H])C(O[H])=C(O[H])C(O[H])=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])O1
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])N=C(N=C1C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C#C[H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C(=C(F)C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)[C@@]1(OC2=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC3=C(Cl)C([H])=C(C([H])=C3[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])N([H])C(=O)N(C1=O)C([H])([H])[C@](C1=C([H])C(Cl)=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C(=C1Cl)C([H])([H])OC1=C2N=C(C([H])=C(C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C([H])([H])C1=C(C(=O)ON1C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
COC(=O)C1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
[H]O\C(\C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H])=C(\[H])C(=O)C(\[H])=C(/[H])C1=C([H])C(OC([H])([H])[H])=C(O[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C2([H])[H])C1=O)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N=C(N([H])[H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[S@@](=O)C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])[C@]([H])(C([H])([H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C#C[C@@]1(OC([H])([H])[H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(C(=O)N([H])[C@@]([H])(C1=NN=C(N1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C#CC([H])([H])N1C([H])([H])C([H])([H])N(C2=C(N([H])C(=O)C3=C([H])C([H])=C(Br)O3)C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2O1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C2O[C@@]3([H])C(=O)C([H])([H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]OC(C1=NC([H])=C(C([H])=C1[H])N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]OC(=O)C([H])([H])[C@]1([H])C(=O)N([H])[C@@]2(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[C@]([H])(C([H])([H])N3C([H])=C([H])C4=C3C([H])=C([H])C(=C4[H])C([H])([H])[H])C([H])([H])\C([H])=C([H])\[C@]1([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SN=N1)C([H])([H])C1=C([H])C([H])=C2C([H])=C(Br)C(=C([H])C2=C1[H])C(F)(F)S(=O)(=O)N([H])[H]
[H]N(C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2\C(=C(/[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@](C([H])([H])[H])(C([H])([H])C([H])=C([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])C([H])=C([H])C1=C(C([H])=C(C([H])=N1)C1=C([H])N(N=C1[H])C([H])([H])[H])C2=O)S(=O)(=O)C1=C([H])N(C([H])=N1)C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2Cl)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(Br)=C2C([H])=C([H])C([H])=C([H])C2=C1OC([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])S(=O)(=O)C(F)(F)F
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C2OC(=NC2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@@]12C([H])([H])C([H])([H])[C@@](C3=NC4=C(N3[H])N(C(=O)N(C4=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C(N([H])C(=O)C(=O)N([H])C2=C([H])C(OC([H])([H])[H])=C(C([H])=C2[H])C2=C([H])N=C([H])O2)=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])ON([H])C(=O)C1=C(N([H])C2=C([H])C([H])=C(Br)C([H])=C2F)C(Cl)=C(OC([H])([H])[H])N=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=NS2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C(SC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
CN(C)CC[C@H](CSC1=CC=CC=C1)NC1=C(C=C(C=C1)S(=O)(=O)NC1=NN(C)C2=C1C=NC(=N2)N1CCN(CC2=C(C=CC=C2)C2=CC=C(Cl)C=C2)CC1)[N+]([O-])=O
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=NC(=C([H])N1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(=N1)C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H])C2([H])[H]
[H]N1C(=O)N([H])C(=O)C(OC2=C([H])C([H])=C(OC3=C([H])C([H])=C(C([H])=C3[H])C3=NC(=C([H])O3)C3=C([H])C([H])=C([H])N=C3[H])C([H])=C2[H])(C1=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(\N=C1/C(=O)N([H])N=C1C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=C(C([H])=NC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N(C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N(C(=O)[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C2C([H])=C([H])C([H])=C([H])C2=C2N([H])C(=C(C(=O)OC([H])([H])C([H])([H])[H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C(N([H])C([H])([H])[H])C(=O)C1=O)C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])[H])C([H])([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F)C([H])([H])C(F)(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])=C1C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C1C([H])=C(C([H])=C2[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]N([H])C1=C(SC2=NC(N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C(=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])\N=C(/[H])C1=C([H])N=C([H])N1C([H])([H])[H]
[O-][N+](=O)C1=CC2=C(NC3=NNC(=C3N=C2C2=CC=CC=C2Cl)C2=CC=CC=C2)C=C1
[H]N(C1=NC(=O)[C@@](S1)(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]12C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C2([H])[H]
[H]N(\C([H])=C1/C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])N=C1[H]
[H]N([H])C1=NC(=C([H])S1)[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N=C(N([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])OC2=C([H])C(=C([H])C(OS(=O)(=O)C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])[H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NOC(=C1[H])C1=C2N(C([H])=C(C2=C([H])C(F)=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]ON([H])C(=O)C([H])([H])N1C([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2N([H])S1(=O)=O
[H]N(C(=O)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]C1=NC(OC2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])C2=C1N=C(N(C2=O)C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=NC([H])=C(C(=C2C(=N1)N([H])[H])C([H])([H])[H])C([H])([H])OC(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])S1)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C2N=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C1=C(C([H])=C2[H])C(=O)N([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)N([H])[C@]2([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(OC(=O)C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(F)=C(C([H])=C1[H])C1=C([H])C([H])=C2C(Cl)=C(O[H])C([H])=C([H])C2=C1[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])O[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C(=C([H])C([H])=N1)C([H])([H])N([H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=C([H])C2=C(OC(F)(F)O2)C([H])=C1[H]
[H]N([H])C1=NN=C(S1)C1=C([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2N=C([H])C3=C2N=C([H])N=C3N([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]1([H])C([H])=C2C3=C4C(N([H])C([H])=C4C([H])([H])[C@@]2([H])N(C([H])([H])[H])C1([H])[H])=C([H])C([H])=C3[H]
[H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
[H]C1=C([H])N(C(=O)C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(C(=O)OC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])\N=C(\N([H])[H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N2C(=NC([H])([H])C2([H])[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C2=C(N=C([H])N(C2=O)C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])[C@]1([H])C(=O)N(C([H])([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NC([H])=C([H])N1C([H])([H])[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)S(=O)(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C1C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C2[H])C1=C([H])C([H])=C(C(N([H])C2=NC([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])N=C2[H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C2N=C([H])C(=C(OC([H])([H])C([H])([H])C([H])([H])N([H])[H])C2=C1[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C1=NOC(=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N1C(=C(C#N)C(=C1C([H])([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=C(\F)C(=O)N([H])C1=C(Br)C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H])\C([H])([H])[H]
[H]N(C(=O)C1=NC(=NC([H])=C1Cl)S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)C(=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])\C([H])([H])[H])C([H])([H])C([H])=C([H])[H]
[H]N([H])C(=O)N([H])C1=C(C([H])=C(S1)C#CC1=C([H])SC([H])=C1[H])C(=O)N([H])[H]
[H]N([H])S(=O)(=O)C1=NC2=C(S1)C([H])=C(N([H])C(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C([H])=C2[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H][C@@]12C[C@H](OC(=O)C3=CC=CC(OC)=C3)[C@@]3(C)OC4=C([C@H](O)[C@]3([H])[C@@]1(C)CC[C@H](OC(C)=O)[C@@]2(C)COC(C)=O)C(=O)OC(=C4)C1=CN=CC=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@@]1([H])C(=O)C2=C([H])C([H])=C([H])C(F)=C2C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(O[H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC1=C(C(=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1C#N)C([H])([H])N(N1C([H])=NN=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C(=C([H])N2[C@]1([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C1(O[H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(F)C(F)=C2N([H])C2=C(F)C([H])=C(I)C([H])=C2[H])C1([H])[H]
[H]\C(=C1/C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C(Cl)=C2[H])C([H])([H])[H]
[H]N([C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(=O)C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C#CC2=C([H])C([H])=C([H])N=C2Cl)C([H])=C1[H]
[H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
CCN1CCC(CC1)OC1=CC2=C(NC(=O)C2=C(C2=NC3=CC(OC)=CC=C3N2)C2=CC=CC=C2)C=C1
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(OC([H])([H])C([H])=C([H])[H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=N\OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])\C([H])([H])[H]
[H]N=C(N([H])C1=C([H])C([H])=C2N(C([H])([H])C([H])([H])C([H])([H])C2=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]OC(=O)C([H])([H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])N(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])S1)C1=NC2=C([H])C([H])=C([H])N([H])C2=N1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])N1N=NN=C1SC([H])([H])C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])S(=O)(=O)OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])[H])C(=O)[C@@]2([H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)O[C@]([H])(C3=C([H])OC([H])=C3[H])C([H])([H])[C@]21C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=O)N([H])[H]
[H]N(C(=O)[C@]([H])(C1=NN(N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C(C#N)=C([H])C([H])=C12)C([H])([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C(=C(/[H])C1=C(C([H])=C([H])C(OC([H])([H])C2=C([H])SC([H])=C2[H])=C1[H])[N+]([O-])=O)\C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C([H])C4=C(C([H])=C3C([H])([H])C2([H])[H])N(C(=O)C([H])([H])O4)C([H])([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(Br)C([H])=C1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(OC(=O)N(C2=C([H])C(=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=NC(O[C@@]2([H])C([H])([H])C3([H])N([C@]([H])(C2([H])[H])C(F)(F)C3([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=NN(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C1=NN=NN1[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C1C([H])=NN2C([H])([H])[C@]([H])(Br)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])SC1=NC(=NN1C([H])([H])[H])C(F)(F)F)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])[C@]([H])(C(=O)N([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])OC2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])C([H])=C(S1)C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(\C(=N\C#N)N([H])C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C2=C(N=C(N2[H])N(C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=NC(=NN2C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])N(C(=O)[C@@]([H])(C([H])([H])C2=C([H])C(F)=C([H])C(Cl)=C2OC([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C#C[H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])S1
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(=O)N([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C1=NC(=O)[C@@](S1)(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])OC1=C([H])C([H])=C2C(N=C(N=C2C2=C([H])C(OC([H])([H])C3([H])C([H])([H])C3([H])[H])=C([H])C(OC([H])([H])C3([H])C([H])([H])C3([H])[H])=C2[H])C([H])([H])C([H])([H])[H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C(Br)=C(N([H])C(=O)C(\F)=C(/C2=C(C([H])=C([H])C(Br)=C2[H])[N+]([O-])=O)C([H])([H])[H])C([H])=C1[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C2=NC(=C3C([H])=C(N([H])C(=O)C([H])([H])OC4=C([H])C([H])=C(Cl)C([H])=C4[H])C([H])=C([H])C3=N2)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])[C@@]2([H])C3=C(C([H])=C([H])C(OC([H])([H])C([H])([H])[H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2C(OC([H])([H])C1=S)(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N1[C@@]([H])(SC([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C(=N\OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])\C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C([H])([H])[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=N1)C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C1=C(OC([H])([H])C(=O)O[H])C(Br)=C(S1)C1=C([H])C(N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
CC1=CC2=C(N1)C=CC(NC(=O)C1CCCCC1)=C2
[H]N1C2=C(C([H])=C(C([H])=C2[H])[N+]([O-])=O)[C@@]2(N(C([H])([H])[H])C([H])([H])[C@]([H])(C3=C([H])C([H])=C(F)C([H])=C3[H])[C@]22C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C2([H])[H])C1=O
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])N1C(=NC2=C([H])C(=C([H])C([H])=C12)N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N([H])C(=O)C1=C([H])OC([H])=C1[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(\[H])=C1/C(=O)N([H])C(=O)C2=C([H])C([H])=C(I)C([H])=C12)C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C(=O)OC2=C([H])C(OC([H])([H])C3=C([H])C(OC(F)(F)F)=C([H])C([H])=C3[H])=C([H])C([H])=C12
[H]N=C1N([H])C(=C([H])C(=C1C#N)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])=O)C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])[C@@]([H])(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N1C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C(OC2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(N([H])C(=O)C2=C([H])OC3=C([H])C([H])=C([H])C([H])=C3C2=O)=C([H])C([H])=C1OC([H])([H])[H]
[H]O[C@](C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C1[H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]1(OC(=O)C(=C1C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C2N=C(C3=C([H])C([H])=C(N([H])C(=O)N([H])C4=C([H])C([H])=C(Cl)C(=C4[H])C(F)(F)F)C([H])=C3[H])C([H])([H])C([H])([H])N([H])C2=NC([H])=N1
[H]N(C(=O)C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1=NC(=C([H])C([H])=C1[H])C1=C([H])C2=C(N=C(N([H])C([H])([H])[H])C3=C2N(C([H])=N3)C([H])([H])[H])N1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)[C@@]1([H])[C@@]2([H])C([H])([H])[C@@]([H])(O[H])[C@@](N([H])[H])(C(=O)O[H])[C@@]12[H]
[H]N1C2=C([H])C([H])=C([H])N=C2N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]N([H])C1=C([H])C([H])=C(\C([H])=C(/[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1SC([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(C([H])=O)=C(N=C1C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])([H])OC(=O)[C@@]1([H])N(C([H])([H])C(=O)C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C1([H])[H])C2([H])[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H])C([H])([H])[H])C([H])([H])C([H])=C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C2=C(C(C(=O)OC([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(O[C@]3([H])N(C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C31)C([H])=C2[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N(N=N1)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C(Cl)C(=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)C([H])([H])C3(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2=O)C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C2=C(C([H])=C([H])C(Cl)=C2[H])N(C(=O)C2=C([H])C([H])=C(N([H])C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1(C2=C([H])SC([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])S1)C1=NN=C(S1)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(F)C([H])=C1C(=O)N([H])C([H])([H])[C@@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(OC(=O)N([H])C([H])([H])C([H])=C([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(ON=C1C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])SC1=NN=C(N1C([H])([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC(=O)C2=C([H])C([H])=C([H])C([H])=C2S1
[H]OC(=O)C(SC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C(=O)N([H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OP(=O)(O[H])OC([H])([H])[C@@]12C([H])([H])[C@]1([H])[C@@]([H])(N1C([H])=NC3=C1N=C(N=C3N([H])C([H])([H])[H])C#C[H])C([H])([H])[C@]2([H])OP(=O)(O[H])O[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1\C([H])=C(/[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])SC(C1=C([H])C([H])=C(Cl)C([H])=C1[H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C(=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C(Cl)C([H])=C(Cl)C(=C1[H])C([O-])=O
[H]\C(=C1\S\C(=N/C([H])([H])C([H])([H])[H])N(C1=O)C([H])([H])C([H])([H])[H])C1=C(N(C(=C1[H])C([H])([H])[H])C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
FC1=C(C=C(CC2=NNC(=O)C3=C2C=CC=C3)C=C1)C(=O)N1CCC2=C3C1CC(=O)C3=CC=C2
[H]N(C(=O)C([H])([H])[H])C1=C2C(=O)C3=C(N([H])N=C3C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H][C@]12N(CC3=CC=CC=C3)CC[C@@]1(C)C1=CC(OC(=O)NC)=CC=C1N2CC1=CC=CC=C1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C(O[H])=C(C(=O)N([H])[H])C2=C1[C@]1(C(O2)=C([H])C(O[H])=C(C(=O)C([H])([H])[H])C1=O)C([H])([H])[H]
[H]N(C1=NC([H])=C(C([H])=C1[H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C(C(OC([H])([H])C([H])([H])[H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OS(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]OC1=C(C2=C(O[C@@](C(=O)[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])(C4=C([H])C([H])=C(N([H])C(=N[H])C5=C([H])C([H])=C([H])S5)C([H])=C4[H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)C4=C([H])C([H])=C([H])C([H])=C4[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(F)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Br)C([H])=C(N([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=NN([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]\C(=C1\S\C(=N/C([H])(C([H])([H])[H])C([H])([H])[H])N(C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=NN(\C(S1)=N/C(=O)C([H])([H])[H])C([H])([H])[H]
[H]SC([H])([H])[C@]1(C(=O)N([H])[C@]([H])(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(C(=C(SC3=C4N=C([H])C([H])=C([H])C4=C([H])C([H])=C3[H])N2[H])C([H])([H])C([H])([H])[H])C(=N1)N([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
CN1CCN(CC1)C1=C2C=C(NC2=NC(N)=N1)C1=CC=C(C)C=C1
[H]O[C@]([H])(C1=C([H])C([H])=C2C(=C1[H])C(=O)C1=C(C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])[H])S2(=O)=O)C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C3=C(N2[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OP(=O)(O[H])C(F)(F)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(N1N=NC2=C1C([H])=C([H])C([H])=C2[H])(C1=NN([H])N=N1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)P(=O)(O[H])O[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=NC([H])=C([H])C(=N2)N([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(OC3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])N(C3=C([H])N=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=NN(N=N1)C1=C([H])C(F)=C([H])C(=C1[H])C1=C([H])C([H])=C(N=C1[H])C([H])([H])[H]
[H]N(\C([H])=C(/[H])C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(S1)C([H])=C(N2C([H])([H])[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C3=NC([H])=C([H])C(=N3)N3C([H])=C([H])C4=C3C([H])=C([H])C([H])=C4N3C([H])([H])C([H])([H])N(C(=O)C([H])([H])C#N)C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[N+]([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C2=C1N([H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1Cl
[H]N1C(=C([H])C2=C1C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])[C@@]1([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])C1=C(C3=C(C([H])=C([H])C([H])=C3[H])C(=O)N1[H])C2([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC(OC([H])([H])[H])=NC(OC([H])([H])[H])=N1
[H]N(C1=NC(=NC2=NC([H])=C([H])N=C12)C1=C(F)C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C(C(=O)N([H])[H])C(=O)C2=C([H])C([H])=C(C([H])=C12)C1=C([H])C([H])=NC([H])=C1[H]
[H]OC(=O)C1=C([H])C(F)=C(C(=O)C2=C(N=C3C([H])=C([H])C(=C([H])N23)C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)N([H])[H])C(F)=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C(=N1)N(C([H])=C([H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C#CC1=C([H])C([H])=C([H])C([H])=C1C#CC([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N(C([H])([H])C1=C(N=C2N1C(=O)C(=C([H])N2C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3C#N)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C(=O)O[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)OC1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1Br)C([H])([H])[C@]1([H])C([H])([H])[N+]([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N(C(=O)C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(N([H])C2=C([H])C([H])=C([H])C(=C2[H])C(=O)C([H])([H])C([H])([H])[H])=C2N=C([H])N([H])C2=N1
[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(Cl)=C1[H])N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])N([H])C([H])([H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(OC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C2N(C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
CCNC(=O)C1=CC=C(S1)C(=O)NCCC1CCN(CC1)C1=C2SC(=CC2=NC=N1)C(N)=O
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C(C(=C([H])C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]C1=C([H])N2C(=C1[H])C(=O)[C@@](OC1=C([H])C([H])=C([H])C([H])=C21)(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1[C@@]1([H])N(N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=S)N([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C([H])C3=C(C([H])=C2C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])N(C(=O)C1=C(N=C(O1)C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=NC([H])=C(N1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C#N
[H]O[C@]1([H])[C@]([H])(C2=C([H])C(=C(F)C(F)=C2N([H])C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1N([H])C([H])=C2[H])C([H])([H])[H]
[H]N(C(=C1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC1(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])OC2=C([H])C([H])=C3C(C([H])=C4C(=O)OC([H])([H])C4=C3C3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(Cl)C2=C([H])C([H])=C([H])C([H])=C2S1)C1=C([H])C([H])=C([H])C(=C1[H])C1=NC2=C(O1)C([H])=C([H])C([H])=N2
[H]C([H])=C([H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])=C([H])[H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])O[C@@]([H])(OC([H])([H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])[C@]([H])(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]1([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])OC([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C(F)(F)F)C([H])=C([H])C([H])=C2[H]
COC1=CC=CC=C1CNC1=NC(NC2CCCC2)=C(C=N1)C(=O)NC1CCN(C)CC1
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)N1N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C1=NC(=C([H])N1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=NS2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)N([H])C(=O)C(N2C([H])([H])C([H])([H])N(C(=O)C3=NC4=C([H])C([H])=C([H])C([H])=C4N=C3[H])C([H])([H])C([H])([H])C2([H])[H])(C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1F)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(OC([H])([H])[H])=NC(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)C1=NN=NN1[H])C([H])([H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])([H])[C@@]2([H])C([H])([H])N(C3=C([H])N=C([H])C([H])=C3[H])C([H])([H])[C@@]12[H]
[H]N([H])C1=C([H])C(=NC([H])=C1C([H])([H])[H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])=C([H])C(C#N)=C1[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])([H])C(=S)N([H])C1=C([H])C(Cl)=C([H])C([H])=C21)C1=C([H])C([H])=C(F)C(=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])C([H])=C([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(OC([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=NC([H])=C(C([H])=C2N=C1C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])SC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C(C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2O1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3N=C(OC3=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])[C@]([H])(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CNC(=O)C1=CC=C(C=C1)C1=C(C2=C(NC[C@@H]3CCCO3)N=CN=C2O1)C1=CC=CC=C1
[H]OC(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C([H])=C(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
CN(C)S(=O)(=O)C1=CC=C2NC(=O)\C(=C/C3=C4C=CC=CC=C4C=C3)C2=C1
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])[C@@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])OC([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=NN(C(=C2C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1F
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])OC(=O)N2C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C(OC([H])([H])[H])C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=C([H])[N+]([O-])=C4[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])N([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C(=O)N([H])[H]
[H]C1=C(C2=C(C([H])=C([H])C([H])=C2[H])N1S(=O)(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])[H]
[H]N(C(=S)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1[H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NSC([H])=C1N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])[C@]2([H])C([H])=NN([H])[C@]2([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)N1C([H])([H])C([H])([H])N(C(=O)N2N=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)[C@@]([H])(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])[N+](=C([H])C([H])=C1C([H])([H])N(C(=O)OC([H])([H])[C@]1([H])OC([H])([H])[C@]([H])(C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C(Cl)SC(=C1[H])S(=O)(=O)N1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C2=C1N=C([H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1SC1=C([H])C([H])=C([H])C([H])=C1C#N)C([H])([H])[H])C(=O)C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C([H])=[N+](C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[N+](C([H])([H])C([H])([H])[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])SC1=NN=C(N1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])N1C([H])([H])[H])N(C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])SC(=N1)C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=O)C2=C(O1)C([H])=C([H])C([H])=C2OC([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(Br)=C(C([H])=C1[H])C([H])([H])N1C(C([H])=O)=C(N=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N=C(N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C(C([H])=C(Cl)C([H])=C1OC([H])([H])C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])OC1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C(C([H])=C([H])N2C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])C([H])=N1)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C2=C(N([H])N=C2[H])C([H])=C1[H]
OC(CNC1CCN(CC1)C1=NC=NC2=C1C(=CS2)C1=CC=CC=C1)COC1=CC(C(O)=O)=C(O)C=C1
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C(=C(OC(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(SC([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1C([H])([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C(N([H])C(=O)C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])=C1[H])C([H])([H])[H])C1=C([H])N=C(N=C1[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
NC1=C2C(SC=C2C2=CC(NC(=O)NC3=C(F)C=CC=C3F)=CC=C2)=C(C=N1)C1=CN=CC=C1
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(F)=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N([H])C1=C2C([H])=C([H])C([H])=NC2=C([H])C([H])=C1[H])C(=O)[C@]12C(=O)C([H])([H])[C@]([H])(C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])N(N=C2C1=C([H])C([H])=C(O[H])C([H])=C1O[H])C([H])([H])C(F)(F)F
[H]OC(=O)C1=C(OC2=C([H])C([H])=C(C([H])=C2N([H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C(F)(F)F)C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C2C(=NC3=C1[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C(O3)C([H])=C([H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C2C(OC([H])([H])[C@]([H])(N([H])C([H])([H])C([H])([H])C([H])([H])C3=C([H])N([H])C4=C3C([H])=C(F)C([H])=C4[H])C2([H])[H])=C(F)C([H])=C1[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(O[H])C(N([H])S(=O)(=O)C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C(C(F)=C([H])C([H])=C12)C([H])([H])[H])C(=O)N1C([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]N1C2=C(SC3=C2C([H])=C([H])C([H])=N3)C(=O)N(C1=O)C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC1=C2O[C@@]3([H])C4=C(C5=C(N4[H])C([H])=C([H])C(=C5[H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C2=C3N=C(N(C3=NC([H])=N2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C1([H])[H])C([H])([H])OC(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C(C([H])=C1[H])C1=C([H])C([H])=C(F)N=C1[H])C1=C(OC([H])([H])[H])C(C#N)=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2O1)C([H])([H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])N1C(=NC(=C1C(=O)OC([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H]
[H]C1=NC([H])=C(C#CC2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])=N1
[H]N(C1=C([H])C([H])=NC(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(OC(=O)C([H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C1=C(C(=NC(=N1)N([H])[H])N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(I)=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=NC(=C([H])C2=C1[H])C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(Cl)C([H])=C2[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])N=C([H])N2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])[C@]1([H])[C@@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])N2C(=O)N(N=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(Cl)C([H])=C2C(O[C@@]([H])(C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C3([H])[H])C([H])([H])N(C2=S)C([H])([H])[H])=N1
[H]N([H])S(=O)(=O)OC1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])N=C(C([H])=N1)C1=NN=C(SC([H])([H])C2=C([H])C(Br)=C([H])C([H])=C2[H])S1
[H]OC(=O)[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3(C(=C([H])C(=O)[C@]4([H])[C@@]5(C([H])([H])[H])C([H])([H])C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@]5([H])C([H])([H])C([H])([H])[C@@]34C([H])([H])[H])[C@]2([H])C1([H])[H])C([H])([H])[H]
[H]O[C@](C1=C([H])N=C([H])N1C([H])([H])[H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C2=C3N(C(=O)C([H])=C(C4=C([H])C(Cl)=C([H])C([H])=C4[H])C3=C1[H])C([H])([H])C2([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])C1([H])[H]
[H][C@]12CN(C)Cc3cccc(Cc4c(O)c(O)ccc14)c23
[H]N1C([H])=C([H])C2=C([H])C([H])=C(C([H])=C12)C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])[C@]1([H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])SC([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])N([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])[C@@]([H])(C1=C(C([H])=C(O[H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(S[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(S[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C2=C(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])N([H])C(=O)N2C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(Br)C([H])=C(C([H])=C2C(=O)C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])=C1Br
[H]N([H])C(=O)C([H])([H])C([H])([H])N1C(=NC2=C([H])C(=C([H])C([H])=C12)C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])C(=O)C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N(C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]3(C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C2(C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)C3=C(C([H])=C(N=C3C([H])([H])[H])C#N)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(C(=O)C2=C([H])N(C(=O)N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C2C([H])=C([H])C(=C3[H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C2N1[C@]([H])(SC2([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]([H])(OC([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1Br)[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]2([H])N(C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)N([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(C2=C(C([H])=C1[H])C(=NO2)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])S(=O)(=O)C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])[H]
[H]N1[C@@]([H])(C2=C(C([H])=C(Cl)C(Cl)=C2[H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)[C@]2([H])OC3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])N([H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C2=NC([H])=C3C([H])=C(C(=O)N(C3=N2)C([H])([H])[H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1SC(=S)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O)[N+]([O-])=O
[H]N1C(=S)N([H])C2=C1C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3N=C(N([H])C3=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=NC(=NC(C2=C([H])C([H])=C(F)C([H])=C2[H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C#N
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC(OC([H])([H])[H])=NC(=N2)N([H])C([H])([H])C#N)=C1[H]
[H]N(C(=O)C1=NN(C([H])=C([H])C1=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])[C@]([H])(C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])N1N=NC(=N1)C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C(C#N)C(=N1)N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N(\N=N\C1=C(Cl)C([H])=C([H])C(=C1[H])C1=C(N=C(N=C1N([H])[H])N([H])[H])C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H][C@@]1(CCCCN1C)[C@H](C(=O)OC)C1=CC(CO)=C(OCO)C=C1
[H]N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])N(C3=C2C([H])=C([H])C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C2=C1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1C2=O
[H]N1C2=C(C3=C1C([H])([H])C1(N([H])C3=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C2N=C(N=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([C@@]1([H])C([H])([H])[C@]11C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(Cl)=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C(F)(F)F
[H]OC(=O)C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1C(=O)O[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])([H])O[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N=C(N([H])[H])C1=C([H])C(OC2=C(F)C(=C(F)C(=N2)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])[C@@]23C([H])([H])C([H])([H])[C@]1(OC([H])([H])[H])[C@]1([H])OC4=C(OC([H])([H])[H])C([H])=C([H])C5=C4[C@]21C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C5([H])[H]
[H]C1=C(C(N2C3=NC(=C(N3C([H])([H])C2([H])[H])C(=O)N(C([H])([H])C([H])([H])C(F)(F)F)C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])=C([H])C([H])=C([H])[C@]12[H]
[H]O[P@](=O)(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C(C2=C([H])C(=C([H])C([H])=C12)C(=O)C([H])([H])[H])C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H]
[H]OC(=O)C1=C([H])SC([H])=C1[H]
FC1=CC=C(NC(=O)NCC2=CC=C(C=C2)C2=NN=C3N2C2=CC=CN=C2NC2=C3C=CC=C2)C=C1
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(S2)C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H][C@@]12CCCN1C(=O)[C@H](CCCCNC(=O)CCC(=O)NCCCCN1CCC(CC1)NC(=O)C(=O)NC1=CC=C(Cl)C=C1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@@H](CSSC[C@@H](NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC2=O)C(=O)NC(CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CC1=CC=C2C=CC=CC2=C1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)C1=CC=C(F)C=C1
[H]C1=NC(OC2=C([H])C([H])=C(N=C2C([H])([H])[H])S(=O)(=O)C([H])([H])[H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@](C([H])([H])C1=C([H])C([H])=C(C([H])=O)C([H])=C1Cl)(C([H])([H])C(C1=C([H])C(F)=C([H])C([H])=C1OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1C([H])=C([H])C2=C([H])C([H])=C3N=C([H])C([H])=C([H])C3=C12
[H]N([H])C(=O)[C@]1(N([H])[H])C([H])([H])[C@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C1([H])[H]
[H]N1C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])N=C(S3)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=NC(=O)C1=C([H])C([H])=C(O1)C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C(Cl)=C1[H])N([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C2N(N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C([H])C1=C2C([H])([H])C([H])([H])O1
[H]C1=NC2=C(C(=NN2C(=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(SC2=NC([H])=C([H])N2C([H])([H])[H])C(Cl)=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(\C([H])=C(/[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C12
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C(=C2[H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C([H])C(=N2)C([H])([H])[H])C1=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(OC2=C([H])C([H])=C([H])C([H])=C2C1=O)C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N1O\C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])=C1/C([H])=C([H])C([H])=C([H])C1=O
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C(OC1=C([H])C([H])=C(Cl)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C#N)C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@](C([H])([H])C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])(C([H])([H])C(C1=C2OC([H])([H])C([H])([H])C2=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]O[C@@]1(C2=C([H])C([H])=C3C([H])=C([H])N(C3=C2[H])S(=O)(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1N=C(OC1=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=C([H])C(F)=C3[H])N3C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
CNC(=O)C1=CN=C(S1)N1CCC2(CC1)CCN(CC1=CC=C(C=C1)C(C)(C)C)C1=C(O2)C=CC=C1
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C(=O)N(C([H])([H])[H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])[H])[C@]1([H])C(=O)N(C(=O)C1([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C(OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C(=O)C([H])([H])N1N=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(C(=O)N([H])C3=C([H])C([H])=C4C(=C3[H])C3=C(C(=NN3C3=C([H])C([H])=C(F)C([H])=C3[H])C(=O)N([H])[H])C([H])([H])C4([H])[H])=C(Cl)C([H])=N2)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])O[H]
[H]N([H])C(=O)C([H])([H])N1C([H])=C(C(=O)[C@@]2([H])N([H])[C@]([H])(SC2([H])[H])C2=C([H])C([H])=C([H])N=C2[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])[C@]([H])(F)C([H])([H])N2[H])=C([H])C(N([H])[H])=C1[H])C1=C([H])C(Cl)=C([H])C(Br)=C1O[H]
[H]N([C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N1N=C([H])C(=C1C1=C([H])C([H])=C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@@](=O)(O[H])O[P@@](=O)(O[H])OP(=O)(O[H])O[H])[C@@]1([H])O[H])N1C(=O)N([H])C(=O)C([H])=C1OC([H])([H])[H]
[H]N(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C(\[H])=C1/C([H])=C([H])C([H])=C(OC([H])([H])[H])C1=O
[H]N(C1=NC(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=NC(=C(O1)C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(OS(=O)(=O)C2=C([H])C(=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C2=C(S1)S(=O)(=O)N(C([H])=C2[H])C([H])([H])C(\[H])=C(/[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@@]([H])(C(\[H])=C(/[H])C2=C(OC([H])([H])C([H])([H])[C@]34C([H])([H])[C@@]5([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C5([H])[H])C3([H])[H])C4([H])[H])C([H])=C(Cl)C([H])=C2Cl)C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC2=C([H])C(Cl)=C(C([H])=C2C(OC([H])([H])C([H])([H])[C@@]2([H])N([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C(=O)N([H])C1=NC([H])=NC([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(OC3=C([H])C([H])=C([H])C(F)=C3C([H])([H])[H])N(C3=C([H])C([H])=NC([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[C@]([H])(C2=NC(=C([H])S2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C(=C([H])C([H])=C3[H])N3C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@]12[H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1N1N=C(C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(F)(F)F)C([H])([H])C(=O)C([H])([H])[H]
[H]C1=C(C2=C([H])C(Cl)=C([H])C([H])=C2N1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C(Cl)C([H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])N(C1([H])[H])S(=O)(=O)C1=NN(N=C1[H])C([H])([H])[H]
[H]N1[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C#N)C([H])([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])[H]
[H]\C(=C(\[H])S(=O)(=O)OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C1N2C(=NC3=C1C1=C(S3)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])\C(=C(/[H])C1=C(Br)C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]ON([H])C(=O)C([H])([H])OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C2([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N=C(S1)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(F)=C1[H]
[H]N(C(=O)C([H])([H])C1=C(N=C(N1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1F
[H]N([H])C1=NC2=C(N=C([H])N2C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C1=C([H])C([H])=C([H])S1
[H]C1=C([H])C([H])=C2N=C(SC([H])([H])C3=NC([H])=C(C([H])=C3[H])N3C(=O)C(C3=O)(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])SC2=C1[H]
[H]N([H])C1=C([H])C(=NC(\C([H])=C(\[H])C([H])([H])[H])=C1C#N)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C([H])=C([H])C1=NC(Cl)=C(OC([H])([H])C([H])([H])OC2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(SN=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4N3C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N1C([H])([H])C([H])([H])N([H])C2=C(C([H])=C([H])C(OC([H])([H])C3=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])[H])=C3[H])=C2[H])S1(=O)=O)C([H])([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2[C@@]([H])(N1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C2=C(OC(=N2)C2=C(N=C([H])C(=C2[H])C2=C([H])N(N=C2[H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])N([H])[H])C([H])=C1C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=C2C([H])=C([H])C([H])=C(C2=NC(=C1[H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C2C(SC3=C([H])C4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])=C([H])N([H])C2=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])S1
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N1C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C1=NOC(=N1)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]2([H])C3=C(C(C#N)=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]12[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C([H])C(N([H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])N=C2C([H])=C1[H]
[H]N1C(=O)C2=C(C1=O)C1=C(N3C4=C1C([H])=C([H])C([H])=C4C([H])([H])C([H])([H])C3([H])[H])C1=C2C2=C(N1[H])C([H])=C(F)C(F)=C2[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]2(C([H])=C([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])N2C2=C1N=C([H])C(Br)=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(\C(=N/C#N)N([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(N=C(SC([H])([H])C3=C(C([H])=C(C(C(=O)C([H])([H])[H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])S2)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])[H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C1=C2C(=NN1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])SC2([H])[H]
[H]O[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])[C@]11C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[S@@](=O)C1=NC2=C([H])C(=C([H])C([H])=C2N1[H])C(F)(F)F
[H]OC1=C(C#N)C2=C([H])C([H])=C([H])C(F)=C2C(SC([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])=N1
[H]N(C(=O)C1=NN=C(O1)N([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])N=C1[H]
[H]N(C1=NC([H])=C(S1)C([H])([H])C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]N([H])C(=O)C1=C2C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])[C@@]21[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=NC3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2N1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C(=O)C1=NOC(=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]C1=NN(C(=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C2OC(=O)N(C2=C([H])C(OC([H])([H])[H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C([H])([H])O[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(C([H])([H])N([H])C2=C([H])C([H])=C([H])C([H])=N2)C1([H])[H]
OCC1=CC=CC(=N1)C#CC1=CC(F)=CC(=C1)C#N
[H]N1N=C2C3=C(OC4=C2C(=C([H])C([H])=C4[H])C1=O)C([H])=C([H])C(=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1N([H])C1=C(N([H])[C@@]([H])(C2=C([H])C(F)=C([H])C(F)=C2[H])C2([H])C([H])([H])C2([H])[H])C(=O)C1=O)C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C2N=C([H])N([H])C(=O)C2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[N+]([O-])=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
CC1=CC=C(C=C1C)C(SCCN)(C1=CC=CC=C1)C1=CC=CC=C1
[H]C1=C(SC2=C1N=C([H])N(C2=O)[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC3=C(OC([H])([H])[H])C([H])=C([H])C(=C3[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C2C(OC([H])([H])[H])=C3[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(O2)C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C2=C(OC(=N2)C2=C([H])C([H])=NC([H])=C2[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC(OC2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)=NC2=C1N=C([H])N2C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C(C2=C([H])SC(=N2)C2=C([H])C([H])=NC([H])=C2[H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C1=C([H])C(=NC([H])=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=NC(=NS1)C1=C([H])C([H])=C(F)C(=C1[H])C(F)(F)F)C([H])([H])[H]
[H]N(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])O[C@@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])[C@@]1([H])C([H])([H])N(C(=O)N([H])[C@]([H])(C([H])([H])N([H])C([H])([H])[H])C([H])([H])[C@@]2([H])C([H])([H])OC([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=O)C(=C([H])OC2=C1O[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(C2=C([H])C([H])=C(F)C([H])=C2[H])=C(C([H])=N1)[C@@]1([H])SC([H])([H])C(=O)N1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2C([H])([H])C([H])([H])[C@]3([H])[C@@]4([H])C([H])([H])C([H])([H])C(=O)[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])C([H])([H])C1([H])[H])C([H])(F)F
[H]O[P@](=O)(C([H])([H])[C@@]([H])(C(=O)N(N([H])[H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N([H])C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O\N=C1\C(\N([H])C2=C([H])C([H])=C([H])C([H])=C\12)=C1\C(=O)N([H])C2=C1C([H])=C([H])C(N([H])[H])=C2[H]
[H]N(C1=NC([H])=NC2=C([H])C(Cl)=C(C([H])=C12)[N+]([O-])=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
NC1=C(C(=O)C2=CC(Cl)=C(Cl)C=C2)C2=C(CN(CCOC3=CC=C(C=C3)N(O)=O)CC2)S1
[H]C1=C([H])C(C#N)=C2N=C(C(=NC2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C(I)N=C23)N([H])OC([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C3=C(O2)C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2[H])N2C(=O)N(N=C12)C1=C([H])C(F)=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C(=O)C([H])([H])C1=C([H])C(OC2=NC(=C([H])C([H])=N2)C2=C(N=C([H])N2C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C2=NN=C3N2C2=C(C([H])=C(Cl)C([H])=C2[H])C([H])([H])N(C(=O)C([H])([H])[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C(N([H])C2=NC(=NC([H])=C2C(F)(F)F)N([H])C2=C([H])N(N=C2[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N([H])C1=C([H])C([H])=C(OC3=NC4=C(S3)C([H])=C([H])C([H])=C4[H])C([H])=C1[H])C2([H])[H]
[H]N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1F)N1C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])N([H])C2=C([H])C([H])=C(C([H])=C12)C(=N[H])N([H])[H]
[H]N(C1=NC(=NC2=C1N=C([H])N2C1=C([H])C([H])=C(C([H])=C1Br)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])C1=C([H])C2=C(C([H])=C([H])C(OC([H])([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])=C2[H])C([H])=C1[H]
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C([H])([H])[H]
[H]N(N([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C(=O)C1=NN(C2=C1C([H])([H])C1=C2C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC1=NC2=C([H])C([H])=C([H])C(N3C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=C([H])C(=C4[H])C4=C([H])C([H])=C([H])S4)C([H])([H])C3([H])[H])=C2O1
[H]OC1=NC(=NC2=C1N([H])C([H])=C2C([H])([H])N1C([H])([H])[C@]([H])(O[H])[C@@]([H])(C([H])([H])O[H])C1([H])[H])N([H])[H]
[H]N1N=C(C2=C(C3=C([H])C(OC([H])([H])[H])=C([H])C(=C3N=C12)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C2N(C3=C(C([H])=C([H])C([H])=C3[H])C2=C1[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])F)C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(N([H])C2=C3N=C([H])N([H])C3=NC(=N2)N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OP(=O)(O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]2([H])C([H])([H])N(C3=NC([H])=C([H])C([H])=N3)C([H])([H])[C@]2([H])C1([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])[C@@]2(N3C([H])([H])SC([H])([H])[C@@]3([H])[C@]([H])(C3=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])[C@]22C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C2([H])[H])C1=O
[H]OC(=O)C(\[H])=C(\C(\[H])=C(/[H])C([H])([H])N(C1=C([H])C(=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])/C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C(O[H])C([H])=C2OC1(C([H])([H])[H])C([H])([H])[H]
FC(F)(F)OC1=CC=C2N(CC3=CC4=C(OCO4)C=C3)C(=O)C(=O)C2=C1
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=C([H])N2N=C(OC3=C([H])C(N([H])C(=O)C4=C([H])C(=NN4C([H])([H])[H])C([H])([H])[H])=C(C([H])=C3[H])C([H])([H])[H])C([H])=C([H])C2=N1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])SC(=S)SC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])C([H])([H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C(OC3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C12)C1=C(Cl)C([H])=C([H])C2=C1OC([H])([H])O2
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])\N=C2/C(=O)N([H])C3=C([H])C([H])=C([H])C(C([H])=C(C([H])([H])[H])C([H])([H])[H])=C23)C([H])=C1[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N([H])C2=C([H])C3=C(N([H])N=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C(=C1[H])C(F)(F)F)C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC(Cl)=C1C1=C([H])C([H])=C([H])C(N([H])[H])=C1[H])N([H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])[C@@]2(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])OC1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])N([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]1([H])C2=C([H])C([H])=C([H])C(=C2C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC(=C2C([H])([H])[H])C([H])([H])[H])N=C(N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])C1=NN=C(O1)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C2N(C(=O)OC([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])N(C2=C([H])C(=C1[H])C(F)(F)F)[C@@]([H])(C1=NN(N=N1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])N1[H])C1=NN([H])C([H])=C1C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H][C@@]12CN(CCC(C3CN(CC(F)(F)F)C3)C3=CC=CC=C3)C[C@]1([H])CN(C2)C(=O)C1=C(C)N=CN=C1C
[H]N(C(=O)C1=C([H])C([H])=C([H])C(N([H])C2=NC(=C([H])C([H])=N2)C2=C3C([H])=C([H])C([H])=NN3N=C2[H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(OC([H])([H])[H])=C([H])C(=N1)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=NC2=C([H])C3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]45C([H])([H])[C@@]6([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C6([H])[H])C4([H])[H])C5([H])[H])=C([H])C([H])=C3N([H])C2=N1
[H]O[C@@]([H])(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)C(=O)N([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C(=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=NN=C(C2=C([H])C([H])=C(Cl)S2)C([H])([H])S1
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=NN(C2=O)C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C3=C(C([H])=C4C(O[H])=C([H])C([H])=C([H])C4=N3)C([H])([H])[C@@]12O[H]
COC1=CC(=CC=C1Cl)N1CCN(CC1)C(=O)CN1N=C(C)C(Cl)=C1C
[H]N(C(=O)C([H])([H])N1C(=O)C([H])([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C(C2=NC([H])=NN2[H])C(=C([H])S1)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])C3=C(C(OC([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C2=C(C(=NN2C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C([H])C([H])=C(C#N)C2=C1[H])N1C(=O)N2[C@@]([H])(C1=O)[C@@]1([H])N(C(=O)OC3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])[C@]2([H])C1([H])[H]
ClC1=CC=C(C=C1)C(C1=CC=NC=C1)C1=CC2=C3N(CCC3=C1)C(=O)CC2
[H]N(\C(=N/C#N)N([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C(Cl)(Cl)C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1OC([H])([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C2=C(N=C(SC3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])C1([H])[H])C1=C(Cl)C([H])=C(C([H])=C1Cl)C(=O)C([H])([H])[H]
[H]N1N=NN=C1C1=NN([H])C2=C1C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
CC(C)(C)NC(=O)C1=CNC2=C1N=C(C=N2)C1=NN(CCCS(C)(=O)=O)C2=C1C=C(OC(F)F)C=C2
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])N(C(SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=N2)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=C(C([H])=C2C#N)C(=O)OC([H])([H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N(C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C2N=C(N=C1[H])N([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
FC(F)(F)C1=CC=C(NC(=O)NC2=CC=C(OC3=NC=NC4=C3C=NN4)C=C2)C=C1
[H]C1=NN(N=N1)C([H])([H])C1=NN(C2=C1N=C(N(C2=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N2C1=NC(=C2C([H])([H])C#N)C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=C(C2=C1N=C([H])N=C2N([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)C1=C([H])C([H])=C2N=C(C([H])=C([H])C2=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(O1)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=NC(=NN1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@@]2(C([H])([H])OC([H])([H])[C@]([H])(C3=C(OC([H])([H])[H])C([H])=C([H])C(=C3[H])N3N=NN=C3C(F)(F)F)C2([H])[H])[C@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=NN2C([H])=C(C([H])=NC2=C1C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C([H])C(OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])=C1[H]
[H]N1C(=NC2=C1C([H])=C(F)C(F)=C2[H])C(=O)N1C([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC(Cl)=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]S\C(=N/C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H])N([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(N2C3=C(C([H])=C([H])C(=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C3(C2([H])[H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C2C([H])=C([H])C([H])=C([H])C2=N1)C([H])([H])[H]
[H]C1=NC2=C(C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])N1S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])[C@@]([H])(C([H])([H])N([H])C(=O)C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@@](O[H])(C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(S1)C1=NN=C(O1)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1C([H])=C(C2=C1C([H])=C([H])C(Br)=C2[H])C([H])([H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N([H])C1=C2C(=NC3=NC(N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C(C#N)C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1=O)C([H])([H])[C@]1([H])OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C(=O)C1=C(N([H])N=C21)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])OC3=C([H])C4=C(N([H])C([H])=C4C([H])([H])C([H])([H])N([H])[H])C([H])=C3[H])C([H])=C12
[H]N(C(=O)N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC1=NC(=C(N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])C2=C(OC([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(=C23)C([H])([H])C1([H])[H]
[H]C1=C(SC(=C1[H])C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=N1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C#N
[H]ON(C([H])=O)[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N1C(=O)N([H])C(C1=O)(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])[C@@]([H])(C(\[H])=C(/[H])\C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H]
[H]N(C1=NC(=NN(C1=O)[C@]([H])(C([H])([H])OC([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C(=C(OC([H])([H])[H])N=C1C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C(C#N)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]ON(\C([H])=C(\[H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=NC(=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C2=C1OC(=N2)N1C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])OC1=C([H])C2=C(N([H])C3=C(C(=O)N([H])[H])C(=NN3C([H])([H])C2([H])[H])C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C(N([H])C2=C([H])N=C([H])N=C2[H])C([H])=C([H])C(=N1)C1([H])C([H])([H])C1([H])[H])C1=C([H])C(=NN1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)C1=C(N(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])[C@]2([H])C([H])([H])[C@]([H])(C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C2N=C(N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C2C(=NC3=C1[C@@]1([H])C([H])([H])C(=C([H])[C@@]([H])(C3([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H])C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H]
ClC1=CC=CC=C1N1C(=O)NN=C1C1=CC2=C(S1)C1=CC=CC=C1OCC2
[H]N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N(C2=NC([H])=NC(N([H])[H])=C12)C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C1[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])C(F)=C2C2=C1C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=NOC4=C3C([H])=C([H])C(F)=C4[H])[C@@]2([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(C1=C2C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=N1
[H]N([H])C1=NC2=C(C(=N1)C1=C([H])C([H])=C(Br)O1)C([H])([H])C1=C2C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(=O)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2(OC3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]C1=NC(=NC([H])=C1N1C(=O)C(Br)=C(OC([H])([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(SC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C1=NN([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C12
[H]O[C@]1(C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
COC1=NC(=O)C2=C(N=C(S2)N2CCOCC2)N1CC1=CC=CC(Cl)=C1C
[H]N(C1=NC(N2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C2C([H])=C([H])N([H])C2=N1)C1=C(OC([H])([H])[H])C([H])=C2C(=C1[H])N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C#N)C(=N\C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])\N1C([H])([H])C([H])([H])C(=C2C3=C(C([H])=C(Br)C([H])=N3)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(N([H])C3=NC4=C(C([H])=N3)C([H])=C([H])C(=O)N4C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
Cl[H].[H][C@@]12CNC[C@@]1([H])C1=CC=CC(=C1C(=O)N2)C(F)(F)F
[H]OC1=C(O[H])C([H])=C2C(N([H])C3=C([H])C(O[H])=C(O[H])C([H])=C23)=C1[H]
[H]N([H])C([H])([H])[C@]([H])(C(=O)N(C([H])([H])C1=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C([H])=C1Cl)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(Cl)C([H])=C(C([H])=C1Cl)C([H])([H])[H]
[H]N([C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2SC([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)S1
[H]N(C(=O)C1=C([H])N(C(=N1)C1=C([H])C([H])=C(F)C([H])=C1F)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C1=N\C(=C(\[H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C(=O)N1C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C2=C(C([H])=C(OC([H])([H])[H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C(Br)=C([H])C(=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]C1=NN2C(SC(=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=N1
[H]C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C(C([H])=N1)C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])O[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(O[H])C([H])([H])[H])C([H])([H])O[H])C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])[H])C([H])(O[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])O[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
CC1=CC(NC(=O)CC(O)=O)=C2CCCC2=C1OC1=CC(C(O)CC2=CC=CC=C2)=C(O)C=C1
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(=NN1[H])C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C(F)=C([H])C([H])=C2O\C1=C(\[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C1=NC([H])=C([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C12
[H]N(C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N([H])C1=O
[H]N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])ON2C(=O)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C3=NOC(=N3)C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C(F)=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
CCC(=O)N1CCC(CC1)NC(=O)NC1=CC=CC(Cl)=C1
[H]N1C([H])=C(C2=C1C([H])=C([H])C(F)=C2[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(F)(F)F)[C@@]1([H])C([H])([H])OC2=C([H])C([H])=C3C(C(=O)N([H])C([H])([H])C3([H])[H])=C2C1([H])[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(Cl)=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
CN1C=C(C2=NC3=C(O2)C=C(CC(=O)N2C[C@@H](F)C[C@H]2CO[C@H]2CC[C@@H](CC2)C(O)=O)C=C3)C2=C1C=CC(F)=C2
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])SC([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N1C(=NC2=C3C([H])=C([H])C(F)=C([H])C3=C3C(=O)N([H])C([H])=C([H])C3=C12)C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(N=C(N2N=C(N=C12)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C#CC([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(OC([H])([H])[H])C([H])=C2N=C(N([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C3=C([H])N=C([H])N3C2=C1[H]
[H]N([H])C1=NC2=NC([H])=C(N=C2C(=N1)N([H])[H])C([H])([H])N([H])C1=C([H])C([H])=C(C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1[C@@]2([H])C([H])([H])[C@@]3([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C2([H])[H])C3([H])[H]
[H]C([H])=C([H])C([H])([H])[C@@]12N([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]([H])(N1C(=O)C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1N([H])[H]
[H]N1C(=O)N([H])[C@@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C(C(=O)OC([H])([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])=C1C([H])([H])[H]
[H]O[C@]1([H])[C@]([H])(O[H])[C@]2(C(=O)N([H])C([H])([H])[H])C([H])([H])[C@]2([H])[C@@]1([H])N1C([H])=NC2=C1N=C(N=C2N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C#C[H]
[H]N(C(=O)C1=C(F)C([H])=C2C(=O)C3=C(N([H])C2=C1[H])C([H])=C([H])C([H])=C3[H])C(C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([O-])=O
[H]N(C(=O)[C@]1([H])N(C(=O)[C@@]([H])(C(=O)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C2[H])C([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
COC1=CC2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=CN=C(C=C3)C3=C(OC)C=CN=C3)C2=O)C=C1
[H]OC(=O)C1=C([H])C(=C([H])C(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)C2=C([H])C(=C([H])C(=C2[H])C(=O)N([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C(=O)O[H]
[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(C2=NC(=C3N2C([H])=C([H])N=C3N([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1(C(=O)N(C(=O)C1([H])[H])C([H])([H])C#CC([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]C1=NN2C([H])=C([H])C([H])=C([H])C2=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])F)C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H])S(=O)(=O)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]OC(=O)[C@@](OC1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C(=NC(=N2)N([H])[H])N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C([H])=N3)C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=C(C(N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(O1)C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C(C(F)=C2N1C(=O)C(=C([H])N2C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C3C([H])=C([H])C(=NC3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=[N+]([O-])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@]([H])(C([H])([H])OC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C(C#N)=C(C([H])=C1O[C@@]1([H])C(=O)N(C([H])([H])C(=O)C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N(C2=NC3=C([H])C([H])=C([H])C([H])=C3C(=C2C1=O)C([H])([H])[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])N1C(Cl)=C([H])N=C(N([H])C([H])([H])C(F)(F)C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
CC(C)N(C(=O)CN1C2=C(C=CC=C2)N(C2=CC=CC=C2)C(=O)[C@@H](NC(=O)NC2=CC(=CC=C2)C(O)=O)C1=O)C1=CC=CC=C1
[H]OC1=C2O[C@@]3([H])C(O[H])=C(C(=O)N([H])[C@]4([H])C(=O)OC([H])([H])C4([H])[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=C([H])C([H])=C(\C([H])=N/OC([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
CC1=C(OC2=C1C=C(C=C2)C1=CC=CC=C1)C(=O)NC1=CN=C(C=C1)N1CCN(CC1)C(=O)NC1=CC=CC=C1C(O)=O
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(C(N([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[C@@]3([H])OC4=C(C([H])=C([H])C([H])=C4[H])N(C([H])([H])[H])C3([H])[H])C(=C2C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(Cl)C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(N(C([H])([H])[H])C([H])([H])[H])=C2C(SC3=C2C([H])=C([H])N(C3=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=N1
[H]N(C([H])([H])C1([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[C@]([H])(N2C(=O)C3=C([H])C(OC4=C(F)C([H])=C(F)C([H])=C4[H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C(=C1[H])C1=C(N=C(S1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])N=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(S[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C2([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(Cl)N=C2N([H])C([H])([H])C1=C([H])C([H])=C([H])C(I)=C1[H]
[H]N([H])C1=C2O[C@@]([H])(C3=C([H])C([H])=C(C([H])=C3[H])[C@@]3([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C4=NC(=NO4)C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])OC2=NC([H])=N1
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C1=NC([H])=C(Br)N=C1C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=NN(\C(S1)=N/S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN(C([H])=N1)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])C([H])([H])C([H])([H])N([H])C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=NC2=C([H])C(C#CC([H])([H])N3[C@]([H])(C([H])([H])[H])C([H])([H])C([H])(C([H])([H])C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])[C@@]3([H])C([H])([H])[H])=C([H])C([H])=C2N1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C2C([H])=C(C([H])([H])N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C1[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]\C(=C(/[H])[N+]([O-])=O)C1=C([H])C(OC([H])([H])C([H])([H])[H])=C(OC([H])([H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@]2(OC(=O)C2=C([H])C([H])=C([H])O2)C(=O)C([H])([H])SC2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C(=O)C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]12[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)OC1=C([H])C([H])=C([H])C2=C1N([H])C([H])=C2C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])S2)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(SC1=C([H])C([H])=C([H])C(=C1[H])C(=O)OC([H])([H])[H])=C(\[H])/C(/[H])=C(/[H])C([H])([H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(N([H])C(=O)N([H])C([H])([H])[H])=C([H])C([H])=C1Cl)C(=O)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C(=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C2\C(=C(\[H])N3C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C2N1[C@@]([H])(C([H])([H])C(OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C2([H])[H])[C@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])[C@]4(C([H])([H])C([H])([H])N(C([H])([H])C5([H])C([H])([H])C([H])([H])OC([H])([H])C5([H])[H])C([H])([H])[C@@]4([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(Cl)=C(N([H])C(=O)[C@@]([H])(N2C(=NC3=C([H])C(F)=C(F)C([H])=C23)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(O[P@@](=O)(O[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N=C(SC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC(=N[H])N([H])[H])N([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N2C(=O)N(C(=O)[C@]2([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C#N)C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])N([C@]([H])(C4=C([H])C([H])=C(C([H])=C4[H])S(=O)(=O)C4=C([H])C([H])=C([H])C(=C4[H])C(F)(F)F)C([H])([H])[H])[C@]([H])(C([H])([H])[H])C3([H])[H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(S[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=NC(=NO2)C2=C([H])C([H])=C(F)C([H])=N2)C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C(F)=C2F)C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])N([H])[C@]([H])(C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C([O-])=O)C([H])([H])C([H])([H])SC([H])([H])[H]
[H]C1=NN(C2=C1C(=NC(=N2)C1=C([H])C2=C(N=C([H])C([H])=C2[H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(C#N)(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])C(=O)C1=NN(C(=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C2=C1C([H])=C(N2C([H])([H])C(=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Cl)C(Cl)=C([H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])N=C(O2)C([H])([H])C2=C([H])C(F)=C(F)C(F)=C2[H])C([H])=C1[H]