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[H]OC(=O)C1=C([H])C(=C([H])C(N([H])C(=O)OC([H])([H])[H])=C1[H])N1C(=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
ClC1=C(Cl)C(=CC=C1)N1CCN(CCCNS(=O)(=O)C2=CC3=CC=CN=C3C=C2)CC1
[H]N(C1=C(C([H])=NC2=C1C([H])=NN2C([H])([H])[C@]([H])(Cl)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N1C(=O)C2=C([H])C(=C([H])C([H])=C2N=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1(N([H])C(=O)C2=NOC(=C2[H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])[C@@]([H])(C1=NC([H])=C(C([H])=C1F)C1=C([H])C(Cl)=C([H])C(Cl)=C1OC([H])([H])C([H])(F)F)C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])(N([H])C(=O)C1([H])N(C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C2([H])N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])(N([H])C(=O)C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])[C@@]1([H])C(=O)N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1N=C([H])C(=C1[H])C1=C([H])C(C2=NC3=C(O2)C(=C([H])C([H])=C3[H])C2=NC([H])=C([H])C([H])=C2[H])=C(N=C1[H])N([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2N(C(=O)[C@@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C2N(C(=O)C(=O)C2=C([H])C([H])=C1[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]N(C(=O)[C@@]1([H])N2C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])N(N=N1)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1N=NC(=C1[H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N2C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=C(F)C(=CC=C1)C(SCCN)(C1=CC=CC=C1)C1=CC=CC=C1
[H]N(C(=O)[C@@]1([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1F)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(SC2=C([H])C([H])=C(Cl)C([H])=C2[H])=NN(C1=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[N+]1=C(C([H])=C(C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=NS(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)[C@]([H])(N([H])C(=O)N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])N([H])[H]
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=C(C2=C(N=C([H])N=C12)N([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(N1C(SC([H])([H])C#N)=NN=C1C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=NN1C1=C(F)C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])[H])C1=C(F)C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C(F)(F)C(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]C1=C(ON=C1OC([H])([H])C#CC([H])([H])[N+]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])N2C([H])=NC([H])=C2C([H])([H])N([C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])S1(=O)=O
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C2=C(SC3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=C(ON=C1C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H]
[H]N([H])C1=C2C(SC(=C2C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])=C2[H])C([H])([H])[H])=NC([H])=N1
[H]OC1=C(C([H])=C(\C([H])=C2/OC(=NC2=O)N([H])OC([H])([H])C([H])=C([H])[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2OC([H])=C([H])C2=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])N2C(SC([H])=C2C([H])([H])N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])=N1
[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)N(C2=C(C1=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C2([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]N(C1=NC(=C(S1)C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C(F)(F)F)C1=C(Br)C([H])=C(Br)C([H])=C1Br
[H]OC1=C(C([H])=C(C([H])=C1I)C([H])([H])[H])C(=O)N([H])C1=C([H])C(Cl)=C(C([H])=C1[H])C(=N[H])N([H])[H]
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC(=NC(=N2)N([H])[H])C([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(N=C=S)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(N([H])C3=NC(=C([H])C([H])=N3)C3=C([H])N=C(N3C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)O[C@]1([H])C(=O)[C@]2([H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]3(OC2(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]13C([H])([H])OC(=O)C([H])([H])[H]
[H][C@@]12CN(CC[C@H](NC(=O)C3CCCC3)C3=CC=CC=C3)C[C@]1([H])CN(C2)C(=O)C1=C(C)C=C[N](O)=C1C
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[H]C1=NC(=C([H])C([H])=C1Cl)N1C(=O)N2C3=C(C([H])=C(N=C13)C([H])([H])[H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C(=NN1C([H])([H])[H])C([H])([H])N1C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C(=C([H])C(=N1)[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C(Cl)C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])[H]
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[H]O\N=C(\N([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])C(=O)[C@@]2([H])N3C(=O)C([H])([H])N(C([H])([H])[C@]3([H])C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C([H])=C2N=C([H])C(=C([H])C2=C1[H])C(=O)N([H])C([H])([H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C2=C(F)C([H])=C(F)C(F)=C2[H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C(C([H])=C([H])C([H])=N1)C(=O)C1=NC(=C([H])C([H])=C1OC([H])([H])C(F)(F)F)N1C([H])([H])C([H])([H])N([H])[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)[C@]1(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C2=NN(C([H])=C2C(=NC2=C1C([H])=C([H])C(Br)=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])N(C2=NC3=C(C(N([H])[H])=C(S3)C(=O)N([H])[H])C(=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C(=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])N2C1=NC2=C([H])C([H])=C(F)C([H])=C2C(C([O-])=O)=C1C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C([H])C([H])=C([H])C(Cl)=C12)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C2=C3C(=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])N=C([H])N1[H])C1=C([H])C(=C(Br)C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C(SC4([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])N=C23)N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C(N=C23)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N=C(S1)C([H])([H])OC1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C(N(C(=O)N(C([H])([H])[H])[C@@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=NC3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C(=O)O[H])C([H])([H])[H])C([H])([H])C(=O)O[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)P(=O)(O[H])O[H]
[H]N=C(N([H])[H])C1=C([H])C(N([H])[H])=C(OC([H])([H])C([H])([H])OC2=C(N([H])[H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])=C1[H]
[H]C1=C(N=NN1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C1=C([H])C([H])=C([H])C3=C1[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C([H])([H])N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC2=C3C([H])=C(SC3=C([H])N=C2[H])C(=O)N([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C2C([H])=C(C([H])=NC2=C1C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=N1)C([H])([H])C([H])([H])[C@@]2([H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C(OC([H])([H])[H])=C(C([H])=C2F)C(=O)N2C([H])([H])C([H])([H])C([H])(N3C(=O)OC([H])([H])C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])=C([H])[C@@]23C4=C(O[C@@]2([H])C1([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C4C([H])=[N+](C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C3([H])[H]
[H]N([H])[C@]([H])(C(=O)N([H])C1=C([H])C(\C([H])=C(/[H])C2=C([H])C([H])=NC([H])=C2[H])=C([H])N=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]ON(C(=O)N([H])[H])C([H])([H])C#CC1=NN(C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C(\[H])=C(/[H])C3=C([H])C([H])=C(C([H])=N3)C3=C([H])C([H])=C([H])C(F)=C3[H])[C@]3([H])[C@]([H])(OC(=O)[C@]3([H])C([H])([H])[C@]2([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)OC([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])N(N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C2=NC3=C(SC4=C([H])C([H])=C(C([H])=C34)C3=C([H])SC([H])=C3[H])C(=O)N2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])S1)C1=C([H])N([H])C([H])=N1
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(N([H])C([H])([H])C(F)(F)F)(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N1C([H])([H])C([H])([H])N([H])C2=C(C([H])=C([H])C(OC([H])([H])C3=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])[H])=C3[H])=C2[H])S1(=O)=O)C([H])([H])[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@]([H])(SC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C(=O)[C@]1([H])[C@]([H])(N([H])C2=C(F)C([H])=NC(=N2)N([H])C2=C([H])C([H])=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C(=C2[H])C([H])([H])[H])[C@@]2([H])C([H])=C([H])[C@]1([H])C2([H])[H]
[H]N1C(=O)N([H])[C@](C1=O)(C1=C([H])C([H])=C(OC2=C([H])C([H])=C3C([H])=NC([H])=C([H])C3=C2[H])C([H])=C1[H])C([H])([H])N1C(=O)C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])C1([H])[H]
[H]OC(=O)C([H])([H])N1C(=O)C(=O)N(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C(=O)N([H])[C@]([H])(C(=O)C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C(N=C1[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NN(C(=O)C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1C#N)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C2C([H])=C(C(=O)N(C2=C1[H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C3=NOC(=N3)C3=C([H])C([H])=C([H])C([H])=C3[H])C(F)=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])C([H])([H])C#CC([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC(=O)[C@]1([H])N(C(=O)C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C2N=C([H])C([H])=C([H])N2N=C1[H])C1=C([H])N([H])N=C1C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])[C@]1(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C2=C(C(=O)N([H])C2=O)C2=C(C([H])=C([H])C([H])=C2[H])[N+]([O-])=O)C([H])=C1Cl
CC(=O)C1=CC=CC=C1NC(=O)C12CC3CC(CC(C3)C1)C2
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(O2)C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C3OC4=C(C([H])=C([H])C(=C4[H])[N+]([O-])=O)C3=C2[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]C(=C(C#N)C#N)C1=C([H])C([H])=C([H])N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C([H])([H])N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N([H])C1=C(C#N)[C@]([H])(C2=C([H])C3=C(N([H])C2=O)C([H])=C([H])C(=C3[H])C([H])([H])C([H])([H])[H])C2=C(O1)C1=C(C([H])=C([H])C([H])=N1)C([H])=C2[H]
[H]OC(=O)C([H])([H])N1C2=C([H])C([H])=C(F)C([H])=C2C(SC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C([H])([H])[H]
[H]N1C([H])=C([H])C2=C([H])C([H])=C(C([H])=C12)C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1[H]
[H]OC(=O)C1=C(SC([H])([H])[H])N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1I)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])([N+]([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])[H]
[H]N([H])C1=C2C(SC(=C2C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C([H])=C([H])C(=C3[H])C(=O)OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])=NC([H])=N1
[H]N(C1=NC([H])=C2C([H])=C([H])N(C2=N1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C(F)C([H])=N2)C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C2([H])[H]
[H]N(C(=O)C1=NN(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=NC2=NC(=NC([H])=C2C([H])=C1C1=C(Cl)C([H])=C([H])C([H])=C1Cl)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]C1=C([H])C(F)=C(C([H])=C1F)C1(C([H])([H])C([H])([H])C(=O)C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])N([H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C([H])=C2OC([H])([H])[H])C(=C1[H])C([H])([H])N([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C([H])C(=C([H])N2C([H])=C1C1=C([H])C([H])=C([H])C(Cl)=C1[H])N1C([H])([H])C([H])([H])C2(C([H])([H])N(C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)C([S@@](=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C([H])C(=C2C([H])=C1[H])C([H])([H])C([H])([H])O[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N1C([H])([H])C(=O)C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(N=C([H])N2C2=NN([H])C(=C2[H])C([H])([H])[H])C(=N1)N([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=N1)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=NC(=NC2=C1C([H])([H])C([H])([H])N(C1=NC([H])=C([H])C([H])=C1C(F)(F)F)C([H])([H])C2([H])[H])N([H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CNC(=O)C1=CN=C(C=C1)[C@]1(O)CCN([C@H]1C)C1=CC(Cl)=C(C=C1)C#N
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=S)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=C(N=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SN=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C(N=C12)C#CC1=C([H])C([H])=C(F)C([H])=C1[H])N([H])OC([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])=C(C(=NC1=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C(\[H])=C(\[H])[C@@]([H])(C#CC2=C([H])C([H])=C3C(C([H])=C(C([H])([H])[H])S3(=O)=O)=C2[H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]N([H])C(=NC(=O)C1=C(C([H])=C(O1)C1=C([H])C([H])=C([H])C(Cl)=C1[H])N1C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC2=C(Cl)C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])C2=C(OC([H])([H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)[C@@]([H])(C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]OC1=C([H])C(Br)=C2C3=C([H])C(O[H])=C(O[H])C([H])=C3N(C(=O)C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])[H])C2=C1O[H]
[H]N(C(=O)C1=C([H])C([H])=C(N=C1[H])N1N=C(C2=C(C(F)=C([H])C([H])=C2F)C1=O)C([H])([H])[H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C(=C(S3)C(F)(F)F)C3=C([H])C([H])=C([H])C([H])=C3[H])C(Cl)=C2[H])C1([H])[H]
[H]N([H])C1=NC([H])=NC(OC2=C([H])C(Cl)=C(N([H])C(=O)N([H])C3=NOC(=C3[H])C([H])([H])[H])C([H])=C2[H])=C1\C([H])=N\OC([H])([H])[H]
[H]N([H])C(=O)C1=C(N([H])C2=C3C([H])=C([H])N([H])C3=NC(=N2)N([H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C([H])S1
[H]N(\C(=C1/C(=O)N([H])C2=C([H])C(=C([H])C([H])=C12)C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(C2=NC3=C(N2[H])C([H])=C([H])C(=C3[H])N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C(=O)C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@]2([H])C1([H])[H]
[H]S\C(=N\C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2C([H])=C(N([H])[H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C3=C(N=C(N3C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])SC([H])=C1[H])[C@@](C1=C([H])N(N=N1)[C@]([H])(C#N)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=NC([H])=C1[H])[C@@]1([H])C2=C([H])C([H])=C([H])C(C3=NC4=C([H])N=C([H])C([H])=C4N3[H])=C2C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(S1)C(=O)OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(SC(F)(F)F)C([H])=C1[H])[C@@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N([H])C1=O
[H]N(C(=O)C1=C([H])SC(=N1)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C(Br)C([H])=C2OC(=NC2=N1)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N1C2=C(C([H])=NN2C([H])([H])[H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(N3N=C(C([H])=C3[H])C([H])([H])[H])C(=C2[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC1(C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C([H])([H])C2=C([H])C([H])=C([H])C(I)=C2[H])[C@]([H])(O[H])[C@]1([H])N([H])[H]
[H]OC1=C([H])C2=C(N([H])C(=C2[H])C2=C([H])C([H])=C([H])C3=C2C(=O)N([H])C3([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C([H])=NC2=C1N=C([H])N=C2N([H])[H]
[H]C1=C(SC2=C1C(=NC([H])([H])C1=NN=C(N21)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C#CC([H])([H])N1C(=O)C2=C3C1=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H]
[H]N([H])C1=NC(N([H])[H])=C(C2=C([H])C(\N=N\N(C([H])([H])C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C([H])([H])C([H])([H])OC(=O)C([H])([H])[H])=C(Cl)C([H])=C2[H])C(=N1)C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])C(=O)N([H])C1=C([H])C2=C(N([H])N=C2[H])C([H])=C1[H])C([H])([H])C(=O)N([H])C1=C([H])C2=C(N([H])N=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C(C(=O)O[H])[C@@]([H])(C2=C(Cl)C([H])=C([H])C([H])=C2[H])C(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])=C(N1C([H])([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N1C(=S)N([H])N=C1C([H])([H])SC1=NC2=C([H])C([H])=C([H])C([H])=C2S1
[H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C1(C2=NN=C3N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C(Cl)C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C(=N1)N([H])[C@]1([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])N=C(C([H])=C2N1[H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C2=C([H])C(Br)=C([H])C(OC([H])([H])C([H])([H])C3=C([H])C([H])=NC([H])=C3[H])=C2O1
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[H]N1C2=C(C3=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2O[C@@]3([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C(=O)C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])[C@]1([H])C1=NN=C(N1C([H])([H])C([H])([H])C(F)(F)F)C([H])([H])N1C(=O)C([H])([H])OC2=C(Cl)C([H])=C(Cl)C([H])=C12
[H]N(\C(=N/C#N)N([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(Cl)N=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
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[H]N(C(=O)C1=C(C([H])=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C1=C([H])C(Cl)=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N1C([H])=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C1=O)C([H])([H])C([H])([H])[H])C(=O)C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]1([H])N2C(=O)[C@@]([H])(N([H])C(=O)C3=C([H])C([H])=C([H])C(Cl)=C3[H])C([H])([H])\C([H])=C([H])/C([H])([H])[C@@]2([H])C([H])([H])OC1([H])[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])C1=C(I)C([H])=C([H])C([H])=C1[H])N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=NC([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])[C@@]([H])(N([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C1([H])[H]
COC1=CC=C2C(OC3=C2N=CN=C3NC2=CC=C3OCOC3=C2)=C1
[H]N(C(=O)N1OC(=O)C(=C1C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]O[C@@]1([H])C2=C([H])C(OC([H])([H])[H])=C(N([H])C(=O)C3=C([H])C4=C(N3[H])C([H])=C([H])C(Cl)=C4[H])C([H])=C2C([H])([H])C([H])([H])C1(F)F
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N1N(C2=C([H])C([H])=C([H])C(SC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])N([H])C1=O
[H]N(C(=O)C1=C(C([H])=C([H])C(=C1[H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])OC([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C(C([H])=C([H])[N+]([O-])=C1C1=C(C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C(=O)C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(\N=C(/[H])C1=C(OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])N(N=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])[H]
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[H]N([H])[C@]([H])(C(=O)N1C([H])([H])SC([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C(Br)=C1[H])C([H])([H])[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]N1C([H])([H])[C@]2([H])N(C3=C([H])C(C#N)=C([H])C([H])=C3C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]O\C(OC([H])([H])[H])=C1\C(=NC(=C(C(=O)OC([H])([H])[H])[C@@]1([H])C1=C([H])C(N([H])C(=O)N([H])C([H])([H])C([H])([H])N([H])C2([H])C([H])([H])C([H])([H])N(C3=C(O[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])N1C(=C(C(=C1C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
FC(F)(F)C1=CC=CC(SC2=NN3C(C=C2)=NN=C3C2=CC=NN2)=C1
[H]O[C@@]([H])(C([H])([H])C(=O)C([H])(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])=C([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(OC(=O)[C@@]1([H])N(C(=O)C(=O)[C@]2(O[H])O[C@@]([H])(C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])[H])[C@@]([H])(OC([H])([H])[H])C(\[H])=C(\[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(O[H])[C@]([H])(OC([H])([H])[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12
[H]C1=NC(=C(Cl)C([H])=C1[H])[C@@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C([H])([H])N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=O)[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C3C(=NC([H])=C([H])C3=C2[H])N([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C#N)C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C([H])([H])C1=C(C(=O)ON1C(=O)N1C([H])([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C([H])=C(Cl)C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C2=C(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C4C(=O)C([H])=C(OC4=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(=O)C([H])=C(N([H])C(=O)\C(=C(/[H])\C(\[H])=C([H])/[C@]([H])(OC([H])([H])[H])[C@@]([H])(OC(=O)N([H])[H])\C(=C([H])\[C@]1([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O
[H]OC(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(OC2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(P([O-])([O-])=O)S([O-])(=O)=O)=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)[C@@]1([H])C2=C(SC([H])([H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])=C([H])C(Br)=C2[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)S[C@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])N([H])C(=O)C(=O)N(C([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C1([H])[H]
[H]C1=C([H])C2=C([H])C(C(=O)C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2OC1=O
[H]OC1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1\C([H])=C(/C#N)C(=O)OC([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
CC1=C(OC2=CC(CC3=NNC(=O)C=C3)=C(O)C=C2)C2=C(CCC2)C(NC(=O)CC(O)=O)=C1
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])S1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C([H])=C(Br)S1)C(F)(F)F
[H]N(C(=O)C1=C(N([H])C2=NN([H])C([H])=C2[C@@]1([H])C1=C([H])C([H])=C([H])O1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N1C(=O)[C@@]2([H])N(C(=O)[C@]([H])(N(C(=O)[C@@]3([H])N(C(=O)[C@]4([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C#C[C@]1([H])N(C(=O)C([H])([H])N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(C#N)C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])C(=O)C([H])([H])C([H])([H])N1C(=O)C2=NC([H])=C([H])C([H])=C2C1=O
[H]N(C1=NN=NN1C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])N1C([H])=NC(=C1C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)[C@@]11C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])N(C3=NC([H])=NC4=C3OC3=C([H])C([H])=C(Cl)C([H])=C43)C([H])([H])[C@@]12[H]
[H]O[P@](=O)(C([H])([H])C(\[H])=C(/[H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C(N([H])C([H])([H])C2=NC(=C(N2[H])C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])=C([H])C([H])=C1[H]
COC1=CC(=CC=C1Cl)N1CCN(CC1)C(=O)CN1N=C(C(Cl)=C1CN(C)C)C(F)(F)F
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[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C2N([H])C(=O)C([H])([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])[H]
[H]N(C1=NC2=C([H])C(OC3=C([H])C(=NC([H])=C3[H])C(=O)N([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C1=NC([H])=NC(N([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C(=N1)N1C([H])([H])C([H])([H])O[C@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C1([H])[H]
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[H]N(C(=O)C1=C(N([H])C(C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])=C([H])N=C2C([H])([H])[H])=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]1([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C(SC2=C1[C@]1(O[C@@]([H])(OC([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])=C(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C2=C(N=C([H])N=C2N([H])C2=C([H])C(Br)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1=C(N([H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])N([H])C1([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)C2=C(C([H])([H])OC(=O)C([H])([H])[H])C([H])([H])S(=O)(=O)[C@@]3([H])N2C(=O)[C@]3([H])OC([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1(C(=O)OC([H])([H])C2=C1C([H])=C1N(C2=O)C([H])([H])C2=C(C3=C([H])C4=C(OC([H])([H])O4)C([H])=C3N=C12)C([H])([H])Cl)C([H])([H])C([H])([H])[H]
[H]O[C@@]1(C#CC([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])[C@@]3([H])C(=C4C(=C([H])C(=O)C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])[C@@]([H])(C3=C([H])C([H])=C(SC([H])([H])[H])C([H])=C3[H])C([H])([H])[C@]12C([H])([H])[H]
[H]N([H])C(=N/[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])\N([H])C1=C(C([H])=C([H])C([H])=C1[H])[N+]([O-])=O
[H]N(C(=O)C1=C([H])C([H])=C(Br)O1)C1=C([H])C([H])=C([H])C(=C1N1C([H])([H])C([H])([H])C2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C(C([H])=C([H])C(=N1)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C2=C(N1[H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])C(Cl)=C1C([H])([H])OC1=C2N=C(C([H])=C(C3=C([H])C([H])=NN3C([H])([H])[H])C2=C([H])C([H])=C1[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=N1
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=N2)=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1N(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=O
[H]OC1=NC2=C([H])C([H])=C([H])C(N3C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=C(O[H])C(=C4[H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])=C2O1
COC1=C(OC)C=C(NC(=O)NC2=CC=C(C=C2)C2=NC(=NC(=N2)N2CCOCC2)N2C3CCC2COC3)C=C1
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
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[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C([H])=C1Cl)S(=O)(=O)C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2N(C(=O)N([H])C([H])([H])C2=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(C([H])=NC2=C([H])C(=NN12)C([H])([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]1([H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N=C2C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C(Cl)C([H])=C(C(=O)N([H])[C@]2([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])N3C([H])=C(F)N=C23)C([H])([H])C1([H])[H]
CN(C(=O)CN1C(=O)OC2=CC=C(C=C12)C1=CC=CC=C1)C1=CC=C(Cl)C=C1
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C12)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])N3C2=NC([H])=C3C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C([H])=C(C2=NC(=NO2)C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])Cl)C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
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[H]N([H])C1=C([H])C(=NC(N([H])C2([H])C([H])([H])C([H])([H])C2([H])[H])=C1C#N)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])[H])[C@@]1([H])N([H])S(=O)(=O)C([H])([H])[H])N1C([H])=NC2=C(N=C([H])N=C12)N([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=NN([H])C(=C2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
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[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=NN([H])C2=NC([H])=C(C([H])=C12)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H]
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[H]N([H])C(=O)C1=C2C(=O)N(C([H])([H])C2=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1
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[H]N(C(=O)C1=NC2=C(S1)C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])[C@]1([H])C([H])([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C1=C([H])C2=C(N([H])C1=O)C([H])=C(Cl)C([H])=C2[H]
[H]N(\C([H])=C1/C([H])=NC2=C1C([H])=C(Br)C([H])=C2[H])N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
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[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC2=C(S1)C([H])=C(OC([H])([H])[H])C([H])=C2[H]
[H]N(C(=O)C1=C(N(C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C2C(=O)N(N=NC2=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])S[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C2=C([H])C(=C([H])C([H])=C2C2=C1C([H])=C(F)C([H])=C2[H])[C@@]([H])(N1C([H])=NC([H])=C1[H])C([H])([H])[H]
[H]C1=NC(C#CC2=C([H])C(=C([H])C(C#N)=C2[H])[N+]([O-])=O)=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])Cl)C1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])C1(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1Cl)[C@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])[C@](C3=C([H])C(O[H])=C([H])C([H])=C3[H])(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[S@@](=O)C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(OC([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C2([H])[H]
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[H]N1C([H])=C([H])C2=C([H])C([H])=C([H])C(=C12)C1=C([H])C(=C2N([H])C(C(=O)[C@@](C2=C1Cl)(C([H])([H])[H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC1=C(F)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])[N+](=C([H])S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])O[C@@]([H])(OC1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(N([H])C(=O)C1=C(C(C(=O)N([H])N([H])C(\[H])=C2/C([H])=C([H])C([H])=C(OC([H])([H])[H])C2=O)=C(N1[H])C([H])([H])[H])C([H])([H])[H])C(\[H])=C1/C([H])=C([H])C([H])=C(OC([H])([H])[H])C1=O
[H]N(C(=O)C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])N2C2=C1N=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C([H])=C(S1)C1=NN(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1C([H])([H])C([H])([H])Cl)C1=C([H])C([H])=C(F)C([H])=C1[H]
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[H]O[C@@]([H])(C([H])([H])OC1=C2C([H])=C(N([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C3=C2C([H])=C([H])S3)C([H])([H])[C@]1([H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])O1)C1=NC(=C(S1)C#N)C1=C([H])C([H])=C([H])C([H])=C1[H]
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O=C(NC12CC3CC(CC(C3)C1)C2)C1=NN(CCN2CCOCC2)C2=C1C=CC=C2
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[H]N1C([H])=C([H])C2=NC(=C([H])C2=C1N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC(=NO1)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3N([H])\C(=N/C(=O)C4=C([H])C([H])=C([H])C([H])=C4[H])N(C3=C2[H])[C@@]2([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C(=O)N(C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C(N([H])C(=C(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C(C(=O)N(C([H])([H])[H])C([H])([H])[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NOC(=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1SC([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
COC1=CC=C(C2=CC(=NN12)C(F)(F)F)C1=NNC(=O)C[C@@H]1C
[H]OC1=C(C([H])=C2C(N([H])N=C2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N2C(=N1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[C@]2(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)O[C@]1([H])C([H])([H])N(C(=O)OC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])[C@@]([H])(C(\[H])=C(/[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C2=C(C([H])=C([H])C(=C2[H])N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C(=O)N(C3=C(C2=O)C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=C([H])C([H])=C2C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C(OC([H])([H])[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C2=C1[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1=NC([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C1=C([H])C(F)=C([H])C([H])=C1F)C1=C([H])C([H])=C(OC2=NC([H])=NN3C([H])=C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C4([H])[H])C(=C23)C([H])([H])[H])C(F)=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C(=O)C2=C([H])N=C3C([H])=C([H])C([H])=C([H])C3=N2)C(=O)[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1N=C(C#N)C(=O)N(C1=O)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
CC(=C)CNS(=O)(=O)C1=CC=C(N)C=C1
CN1C(=O)N(C2CCN(CC2)C(C)=O)C2=C1C=NC1=CC=C(N=C21)C1=C2C=NNC2=CC=C1
[H]N(C(=O)C([H])([H])C1=NC2=C(N1[H])C(=C([H])C([H])=C2[H])C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]C1=NC(OC([H])([H])[H])=C([H])C([H])=C1N(C(=O)N1C([H])([H])C([H])(OC2=C(C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C1([H])[H])C([H])([H])[H]
[H]N(N([H])C1=C2C([H])=C(C([H])=C([H])C2=NC1=O)[N+]([O-])=O)C(=O)C1=C([H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N([H])C(=O)C(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)C2=C([H])C([H])=NC3=C2C([H])=C([H])N3[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])SC1=NN=C(O1)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(N([H])C([H])=N2)C(=N1)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12
[H]O[C@]1([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C(O1)C([H])=C([H])C(OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=NN(C2=C1C([H])=C(C([H])=C2[H])C1=C(C#N)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])[C@@]2(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=O)\C(N1[H])=C1\C2=C(N([H])C3=C(N([H])[H])C([H])=C([H])C([H])=C23)C(=O)N([H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2C2=NN=C([H])N2[H])C2=C([H])N=C([H])C([H])=C12)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1F
[H]OC1=C(C(OC([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(OC([H])([H])C(=O)OC([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1([H])[H])C1=NC(=NC(=C1[H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(O1)C([H])([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])[C@]([H])(N1C([H])=NC([H])=C1[H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N([H])C(=O)C2(N(C3=C([H])N=C(OC4=C([H])C([H])=C(C([H])=C4[H])C4=NC(=C([H])O4)C4=C([H])C([H])=C([H])C([H])=C4F)C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C1=O
[H]N1C(=NC([H])([H])[C@@]1([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])[C@@]([H])(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N=C(O1)C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(C2=C1C([H])([H])C(C1=C([H])C([H])=C(Br)C([H])=C21)(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=C([H])N=C([H])C(=N1)N([H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=N1)C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C1=C(C3=C(C([H])=C([H])C([H])=C3[H])C(=O)N1[H])C2([H])[H]
[H]N1C2=NC(=C([H])C([H])=N2)C2=C([H])C(OC([H])([H])C([H])([H])\C([H])=C([H])\C([H])([H])N([H])C3=C([H])C1=C([H])C([H])=C3[H])=C([H])C([H])=C2[H]
[H]C1=C([H])C(=C(C([H])=C1C(=O)N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
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[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C1(C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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CC1=C(Cl)C(=NN1CC(=O)N1CCN(CC1)C1=CC=C(F)C=C1)C(F)(F)F
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[H]N(C(=O)N1C([H])([H])[C@@]2([H])N(C(=O)[C@]3(C([H])([H])C([H])([H])[C@@]([H])(N([H])[C@]4([H])C([H])([H])C([H])([H])OC([H])([H])[C@@]4([H])F)C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])N(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2F)C1=O
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[H]N(C(=O)N([H])[C@@]1([H])C(=O)N(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(N([H])C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C1=C([H])C2=C(N([H])N=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C2C(=NN=C2C([H])([H])[H])N=C(SC([H])([H])C(=O)N([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])N1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])C(=O)N2C3=C(OC4=C2C([H])=C([H])C([H])=C4[H])C([H])=C([H])C([H])=C13)C1=NC([H])=C([H])S1
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[H]OC(=O)C([H])([H])N([C@@]1([H])C(=O)N(C2=C(F)C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C(Cl)C([H])=C([H])C2=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])[C@@]3([H])[C@]1([H])C([H])([H])C2=O
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[H]N(C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N1C([H])=C([H])C([H])=C1C1=C2C(=O)N([H])C3=C([H])C([H])=C(F)C(=C23)C(=C1[H])C([H])([H])[H]
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[H]N(C(=O)N([H])C1=C(C2=C([H])C(=C([H])C(=C2N=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]N(C(=O)C([H])([H])C([H])([H])[H])C1=NN2C(S1)=NN=C2C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
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[H]N([H])C1=C([H])C(=NC2=C([H])C([H])=C(N([H])C(=O)C(\[H])=C(/[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1(C#CC([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])[C@@]3([H])C(=C4C(=C([H])C(=O)C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])[C@@](Cl)(C3=C([H])C(Cl)=C(N(C([H])([H])[H])C([H])([H])[H])C(Cl)=C3[H])C([H])([H])[C@]12C([H])([H])[H]
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[H]N1C([H])=C([H])C([H])=C1\C([H])=C1/C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@]2(C([H])=C([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(C1=NN=NN1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C(=NC(OC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=N1)C(F)(F)F)S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])N2C(=O)N3C([H])([H])C([H])([H])C([H])([H])[C@]3([H])C2=O)C([H])([H])C1([H])[H])C(F)(F)F
CS(=O)(=O)C1(CCOCC1)C1=CC(=NC(=N1)C1=CC=CC2=C1C=CN2)N1CCOCC1
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C1([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C(Cl)=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])[C@]1([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(C([H])=C([H])[N+]([O-])=C1C1=C(Cl)C([H])=C([H])C([H])=C1[H])C(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[C@@]2([H])ON=C(C3=C([H])C([H])=C(C([H])=C3[H])C(=N[H])N([H])[H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC1=NC(=C(N1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C2N(C(=C(C2=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=NC([H])=NC2=C([H])C([H])=C(C#CC([H])([H])N([H])C(=O)C([H])([H])OC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C(=O)N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1N=C([H])C(OC2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C(OC([H])([H])[H])C([H])=C23)=C1[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N1N=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=NC(=N2)N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N3N=NC(=C3[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C2([H])[H])N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C#C[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]1([H])N(C(=O)[C@@](N([H])C(=O)ON2[C@@]3([H])C([H])([H])[C@@]4([H])C([H])([H])[C@]2([H])C([H])([H])[C@@]([H])(C3([H])[H])C4([H])[H])(C([H])([H])[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC1=NC2=C(N1C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=NC2=C(S1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])C(=O)O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C1C([H])([H])C([H])([H])O[C@]11C([H])([H])C([H])([H])[C@@]2([H])[C@@]3([H])C(=C4C(=C([H])C(=O)C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])[C@]([H])(OC([H])([H])[C@]12C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2C(C(=O)C1(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C(S1)C#N)C([H])([H])[H]
[H]OC([H])([H])[C@]1(C([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]23C([H])([H])[C@]22C(=O)C([H])([H])[C@]4(C([H])([H])[H])[C@@]([H])([C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[C@@]4(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]13[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H])S(=O)(=O)C1=C(C2=C(S1)C([H])=C([H])C(Cl)=C2[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]OC(O[H])(C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC3=C([H])C(F)=C(F)C([H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[C@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=NN(N=N1)C1=C([H])C([H])=C([H])C(=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
CC1=C(OC2=CC=C(C=C2F)N2C=NN=N2)N=CN=C1N1C2CC3CC1CC(C2)N3C(=O)OC1(C)CC1
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[H]OC1=C(OC([H])=C([H])C1=S)C(=S)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=NC2=C1N=C([H])N2C([H])([H])[H])[C@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
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[H]C1=C([H])C([H])=C(O1)C1=NN2C(=N1)C1=C([H])N(N=C1N=C2N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C1(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=N2)C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])[C@@]([H])(C1=C([H])N=C(Cl)C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]N1C([H])=NC2=C1N=C(N1N=C(N=C21)C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(F)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C2N=C(N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]N(\N=C1/C(=O)N([H])C2=C1C(Cl)=C([H])C([H])=C2C([H])([H])[H])C(=O)[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2C([H])=C3N(C2=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C3=O)C1=NC2=C(C([H])=C([H])C(Cl)=C2[H])N1C([H])([H])C([H])([H])[H]
[H]N(N([H])C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])S1
COC1=CC(=CC=C1)C1=C(CN(C)CC1)C(=O)OCCC1=CC2=C(OCC2)C=C1
[H]N(C(=O)OC1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(C([H])=O)C([H])=C2C([H])([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C(=O)N([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C4OC([H])([H])OC4=C3[H])C([H])([H])N(C(=O)C([H])([H])C3=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=C(C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C1=C([H])C([H])=C2N=C([H])N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN=NN1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C(=C23)C1([H])[H]
[H]N([H])C1=NC2=C(C([H])=C([H])C([H])=C2OC([H])([H])[H])C(=N1)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(Cl)S1)C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=NC2=C(S1)C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
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[H]OC(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=NN([H])C3=C2C(=NC([H])=N3)N([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C(F)=C([H])C([H])=C3[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]O\N=C(/C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)N1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(=C1[H])C(C1=C([H])N([H])C([H])=N1)=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]C([H])([H])N(C#N)C([H])([H])C(=O)O[C@@]([H])(C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C(\C([H])=N\OC([H])([H])[H])C(=NC([H])=N1)N([H])C1=C([H])C2=C(N([H])N=C2[H])C([H])=C1[H]
[H]OC1=C(O[H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]N1C([H])=C(C2=C([H])C([H])=C([H])N=C12)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C2=C(C([H])=N1)N(C1=C([H])C([H])=C([H])C([H])=C21)C([H])([H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C(C([H])=C([H])C(=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N1C(=O)N(C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(N([H])[H])C(=O)N([H])C1([H])C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])O[H])C([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
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[H]N=C(N([H])[N+]([O-])=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]1([H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C2=C([H])C([H])=C(C(Cl)=C2[H])C([H])([H])[H])C1([H])[H]
[H]N1C([H])([H])C2=C(C3=C([H])C([H])=C(C([H])=C3N2C([H])([H])[H])N2C([H])=C([H])C(=C([H])C2=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])[H])C([H])([H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]C([H])([H])[C@]1([H])O[C@]([H])(C([H])([H])[H])C([H])([H])N(C2=NN=C(S2)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=N1
[H]N1N=C2C(=C([H])C1=O)C1=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C2([H])[H]
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[H]N([H])C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1(N(N=C(C2=C([H])C(F)=C([H])C([H])=C2F)C1([H])[H])C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NN=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N=C(C([H])=C2[H])C(F)(F)F)C([H])([H])[C@]1([H])F
[H]OC(=O)C1=C(SC2=C1C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H])N([H])[H]
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[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C(OC(F)(F)F)C([H])=C([H])C(N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]
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[H]C1=C([H])C(=C([H])C([H])=C1S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C1([H])[H]
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[H]N1C([H])=NC(=C1[H])C([H])([H])N1C2=C(C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N([C@]([H])(C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
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[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC2=C(C3=C(C([H])=C2[H])C(=NO3)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])C([H])([H])[H]
[H]OC1=C2C(=NC(=N1)N([H])[H])N([H])C(=C2SC1=C([H])C(=C(Cl)C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=C(OC([H])([H])[H])C([H])=C3C([H])=C(OC4=C([H])C5=C(C([H])=C([H])C(=O)O5)C([H])=C4[H])C(=O)OC3=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2SC([H])=C(C2=C1[H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H]
[H]N1C(=O)N([H])C(=O)C(N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])(C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C(N=C(Cl)C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
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[H]N(C1=NC([H])=C2C([H])=C(C(=O)N([H])C2=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N=C(S2)N([H])C2=NC([H])=C([H])N2[H])C([H])=C1[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C2=C(N=C([H])C([H])=N2)N=C1[H])C([H])([H])[C@]([H])(C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C(C(=O)N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
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[H]OP(=O)(O[H])[C@]([H])(C(=O)N([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])N(C2=C1C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])S(=O)(=O)N(C1=C(C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)C2=C(C1=O)C1=C(C([H])=C(OC([H])([H])[H])C3=C1N(C([H])=C3[H])C([H])([H])[H])C1=C2C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])[C@]([H])(Cl)C([H])([H])[C@@]([H])(O[H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])[C@]1([H])OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]1([H])OC1=C([H])C([H])=C([H])C(Cl)=C1C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])N(C1=O)C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]4([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C(N(C2=NC(=C([H])C(=N2)C([H])([H])[H])N(C([H])([H])C2=NN=NN2C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(Br)=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Br)O1)C1=NC2=C(S1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=NOC(=C1[H])C([H])([H])OC1=C([H])C2=C(N=C([H])C([H])=C2[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(Cl)=C(OC2=C([H])C3=C([H])C([H])=C([H])C([H])=C3N=C2[H])C(Cl)=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C(O1)C1=C([H])C(=C([H])C(F)=C1[H])N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=N1
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C(=O)C1=C(N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NN=C(C([H])=C1[H])C1=C([H])C([H])=C(C(N([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])C([H])=C2[H])=C1[H])C([H])([H])[H]
[H]N1C(=O)C([H])=C(C2=C([H])C([H])=C(F)C(F)=C12)C([H])([H])N(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=NC([H])=C([H])C([H])=C1C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C(\[H])=C(/[H])[C@@]1([H])[C@]([H])(O[H])C([H])([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C1(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C([H])=C([H])C(=N1)C([H])([H])[H])C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C([H])C([H])=C4OC(=NC4=C3C([H])([H])C2([H])[H])C(F)(F)F)N1C([H])([H])[H]
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[H]N([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])[C@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)[C@]([H])(N([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]C1=C(SC(=C1[H])C1=NC(=NO1)C1=C(F)C([H])=C(F)C([H])=C1[H])C(=O)C(F)(F)F
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[H]OC([H])([H])C1=C(N=C(C(=C1C1=C(N([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N2C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C(F)(F)C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1Cl)C(F)(F)F
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(C([H])([H])C([H])([H])OC([H])([H])[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C2=C(N1[H])C(Cl)=C(Cl)S2
[H]N(C(=O)C1=C([H])C(N([H])C2=NC(=C([H])S2)C2=C([H])C([H])=C([H])N=C2[H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C1=C([H])N(N=N1)C([H])([H])[H])C(F)(F)F
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1(N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(SC([H])([H])[H])C([H])=[N+]([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])N1C2=C(C([H])=C([H])C([H])=C2[H])C(=C1C1([H])C([H])([H])C1([H])[H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C1N([H])C(=O)C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C2=C(N=C([H])C([H])=C2[H])N1C([H])([H])C#N)[C@@]1([H])C([H])([H])N(C2=NC([H])=C([H])C(=N2)C2=C([H])C3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C#N)[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(SC(=N1)[C@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
NCCSCCC1=CNC2=CC=C(F)C=C12
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@](OC1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])[C@]([H])(OC1=NC(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=N1)C(=O)OC([H])([H])[H]
[H]N(C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C(N([H])C2=C([H])C([H])=C(Br)C([H])=C12)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1([H])C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])=C([H])C([H])=C2[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1N=C([H])C2=C([H])C(Cl)=C(Cl)C([H])=C12
[H]N([H])C1=C(C([H])=C([H])C(Cl)=N1)C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])N(C3=NC([H])=C(N=C3Cl)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])[C@]([H])(O[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@@]1(O[H])C([H])([H])[H])C([H])([H])OC(=S)N([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N(C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N([H])C([H])=N1
[H]OC([H])([H])[C@@]([H])(N([H])C1=NC2=C(N=C([H])N2[C@]2([H])O[C@]([H])(C3=NN(N=N3)C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])[C@@]2([H])O[H])C(=N1)N([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C2C(=O)N([H])C(=O)C(=O)C2=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=C(C([H])=C2C#N)C(=O)OC([H])([H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C(=O)N([H])C1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]N(C(=O)C1=C([H])C([H])=C2C(=O)N(C(=O)N([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C2(C3=C(C4=C(N3[H])C3=C(C([H])=NC(=C3[H])C3=C([H])C([H])=C([H])C([H])=C3F)C([H])([H])C4([H])[H])C(=O)N([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C2N(C([H])([H])[H])[C@@]3([H])N(C([H])([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])[C@]3(C2=C1[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(OC2=C(F)C(=C(F)C(OC3=C([H])C([H])=C([H])C(F)=C3[H])=N2)C([H])([H])[H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(=C([H])C(Br)=C1[H])C(F)(F)F)C(F)(F)F
[H]C1=C([H])C(=C(F)C([H])=C1Cl)[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H]
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(OC3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])=C2[H])C([H])=C1[H]
[H]C1=NC(=NC([H])=C1[H])C1=NN=NN1C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(N([H])C(=N[H])N([H])[H])=C([H])C([H])=C2[H])C(=C1[H])C([H])([H])C([H])([H])[H]
[H]N1C(=NC2=C1C([H])=C([H])C(F)=C2C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C([H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(C([H])=C1[H])C([H])([H])[H]
CCC1=NN2C(C=CC=C2C2=C(OC)C=C(C)C=C2OC)=C1N(CC1CC1)CC1CCOCC1
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(SC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C(=O)OC([H])([H])[H])C(=O)OC([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
CCN(CC)C1=CC=C(CN(CC2=CC=CC=C2)S(=O)(=O)C2=CC3=CC=CC=C3C=C2)C=C1
[H]O[C@]1(N2C(=NC([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1F
[H]N=C(SC([H])([H])C([H])([H])C1=C([H])N=C([H])N1[H])N([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N(C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=[N+](C([H])=C1[H])C([H])([H])[H]
[H]N1C2=C([H])C(=C([H])C([H])=C2O[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H])N1C([H])=NC2=C(SC(=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1=O
[H]N([H])C1=C(C([H])=C([H])C(Cl)=N1)C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])N(C3=NC([H])=C(N=C3C(F)(F)F)C(=O)N([H])C([H])([H])[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C3N(N=NC3=C2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])N1C([H])=C(C2=C1C([H])=C([H])C(=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C(C([H])=C([H])S1)C1=NC2=C([H])C([H])=C([H])C([H])=C2S1)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C3N=C(N=C(O[H])C3=C2[H])N([H])[H])C([H])=C1[H])C(=O)O[H]
[H]N([H])C1=C(N([H])[H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=C(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C2=C([H])C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])N(C(=N2)C2=C([H])C([H])=C(C([H])=C2F)C([H])([H])[H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C2[H])[C@]([H])(C([H])([H])OC([H])([H])C(=O)O[H])C1([H])[H]
[H]C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=NC(=NO2)C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C1=NN=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]C1=NC2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C(=N1)N1C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C([H])=C([H])C([H])=N2)C1([H])[H]
[H]OC1=C2C([H])=C(C([H])=NC2=NC(=C1[H])C1=C(C([H])=C([H])S1)C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@]2([H])\C([H])=C([H])/C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(OC(=O)\C([H])=C([H])/[C@@]([H])(O[H])[C@]2([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C2N(C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(OC1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([O-])=O
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C2=C(C([H])=C(C([H])=C2C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N1C([H])=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C1=O)C([H])([H])C([H])([H])[H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)N([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])C([H])=C2C(=NN([H])C2=C1[H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NC(=C([H])C([H])=C1[H])N1C([H])=C([H])C2=C1N=C(N=C2[H])N([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(Cl)SC(=C1[H])S(=O)(=O)C1=C([H])N(C2=NC([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)O[C@]([H])(C1=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])O2)C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1F)C1=NC(=C2N1C1=NC(OC([H])([H])[H])=C([H])C([H])=C1N=C2C([H])([H])[H])C(F)(F)F
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=NN(C(=O)O1)C([H])([H])C([H])([H])C#N
[H]N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O\N=C1\C2=C(O[C@@]3(C(=O)N([H])C4=C([H])C([H])=C([H])C([H])=N4)C([H])([H])[C@@]13[H])C([H])=C([H])C([H])=C2[H]
CCC(=O)OC1=CC=C(N=C1C1=CC=C(C=C1)C#C[C@]1(CN2CC3=C(C=C(OC)C=C3)C2=O)CC(=O)NC1=O)C1=CN(C)N=C1
[H]N(C1=C2C([H])=C([H])C([H])=C([H])C2=C(N=N1)C1=C([H])C([H])=C([H])C2=NC([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=NC(=C(S1)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]([H])(O[H])C([H])([H])SC1=NC(=C(N1C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])C#CC([H])([H])OC1=NC2=C(C(=O)N1[H])C(=C([H])C(=O)O2)C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=NC2=C([H])C([H])=C(F)C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1Br)C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])[H])C([H])([H])O[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
CN1C=CC2=C1C(OC1=CC=C(NC(=O)NC3=CC=C(Cl)C=C3)C=C1)=NC=N2
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C(C([H])=C(O[H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C(C([H])=N1)[C@@]1([H])C([H])([H])[C@@]2([H])N(C3=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)N1C([H])=C([H])N=C1C1=C([H])[N+]([O-])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(O[C@@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2N(C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NN2C(S1)=NC1=C([H])C([H])=C([H])C([H])=C1C2=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC(=O)C(\[H])=C(/C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C(F)C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]C1=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC(OC2=C(N=C([H])C([H])=C2[H])C([H])([H])[H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]2([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])SSC2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])OC([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1(C2=C([H])C3=C(C([H])=C2C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
CCC(=O)N1CCC(CC1)NC(=O)NC1=CC=CC(Cl)=C1
[H]N([H])C(=O)C1=C([H])C2=C(C([H])=C1F)N(C(=N2)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C1=NC(=C(S1)C([H])([H])N(C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C(F)(F)F)C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=C([H])N(N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O)C(=O)OC([H])([H])[H]
[H]N1N=NN=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NN(C2=NC(SC([H])([H])[H])=NC(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C12)C([H])([H])[C@]([H])(Br)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C2C(OC([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])C3=C([H])N([H])C4=C3C([H])=C(F)C([H])=C4[H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C2([H])[H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N([C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])N=C([H])C(C#N)=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])N(N=C1C(F)(F)F)C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])C(Br)=C([H])C(=C1N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=NC2=C([H])C([H])=C(C([H])=C2N1C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2N(C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=NC2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1C#CC([H])([H])C([H])([H])N1C([H])([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C(C(=NC2=C([H])C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C(=C(/[H])C1=C(C(=O)C(=C(C1=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])[H])\C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC(=O)OC([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@]1([H])[C@]33C([H])([H])C([H])([H])N(C([H])([H])C4([H])C([H])([H])C4([H])[H])[C@]([H])(C2([H])[H])[C@@]32N=C([H])[C@]1(O[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C([H])C([H])=C(C#N)C([H])=C12)C1=C([H])C([H])=C(F)C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])[H]
CCCC(=O)NC1=NNC2=CC(Cl)=C(C=C12)C1=CC=C(C=C1)N(O)=O
[H]OC(=O)C([H])([H])C(=O)N([H])C1=C(C(=C(OC2=C([H])C(=C(O[H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C1=NC(=C([H])C(=N1)C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C(=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2N=C1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(Cl)=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(SC2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C2[H])C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C(C2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C1=C(C([H])=C(O[C@@]3([H])C([H])([H])[N@]4C([H])([H])C([H])([H])[C@]3([H])C([H])([H])C4([H])[H])C([H])=C1[H])S2(=O)=O
[H]N([H])C1(C(=O)N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C2=NS(=O)(=O)C3=C([H])C(F)=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C1=C(N=C(O1)C1=C2C([H])=C([H])C(=NC2=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(OS(=O)(=O)N([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(/[C@]([H])(N1C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2(C3=C([H])C(=C([H])C(F)=C13)C1=C([H])C([H])=C(C#N)N1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1C1=NC(=NC(=C1[H])C([H])([H])[H])N(C1=C(Br)C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N([H])C(=O)C1=C(N([H])C(=C(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C(C3=C([H])C([H])=C([H])C([H])=C3[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(S1)C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C(F)C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1(C([H])([H])S[C@@]([H])(C2=C([H])C(\C([H])=C(/[H])C3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=C(/[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[N+]([O-])=O)\C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H][C@@]12CC[C@@]3(C)[C@@H](C[C@H](OCOCC[Si](C)(C)C)C(=O)[C@]3([H])[C@@]1(C)C[C@H](OC2=O)C1=COC=C1)C(=O)OC
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N(N=C1N([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)C([H])([H])SC1=NN=NN1C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CCC(C)OC1=NO[N](O)=C1S(=O)(=O)C1=CC=CC=C1
[H]OC(=O)C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C(N=C1[H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])=C(C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C2=NC3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N3[H])C1([H])[H]
[H]N1C(=O)N(C(=O)C2=C1C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C(N=NS1)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C(C1=C([H])C(=C([H])C([H])=C1[H])C(N([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C2N(C(=O)SC2=C([H])C(=C1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C#N)C([H])=C(C([H])=C1[H])C([H])([H])N1N=C([H])N=C1[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])C2([H])[H]
[H]C1=NC(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])C([H])(C(=N\OC([H])([H])[H])\C4=C([H])C([H])=C(Br)C([H])=C4[H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C2=C(OC(=C2C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C2C([H])=C([H])C([H])=C3C(=O)N([H])C(C([H])=C1[H])=C23
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2N(C2=C([H])C([H])=C([H])C([H])=C2F)S1(=O)=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C(C([H])=C(OC([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])=C1[H])[C@@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]C1=C(N(C2=C1C([H])=NN(C1=C([H])N=C(C([H])=C1[H])N1C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1([H])[H])C2=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=NC([H])=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C3=C2OC(=C([H])C3=O)C([H])([H])[H])C(C(=O)C([H])([H])[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
BrC1=CC2=C(NC3=NC=CC=C3N3C(=NN=C23)C2=CC=C(CN3CCC(CC3)C3=NN=C(C3)C3=CC=CC=N3)C=C2)C=C1
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[H]N(C([H])([H])C([H])([H])OC1=C([H])C(Cl)=C([H])C2=C1OC([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(C#N)=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])[N+]([O-])=O)C1=C([H])C2=C(C([H])=C1[H])N(C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N=C(O1)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])[C@@]1(C(=O)N(C2=C([H])C([H])=C(Cl)C([H])=C12)S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C(=O)N(C1=C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1C1=C(N([H])C(=O)C2=C([H])C([H])=C3N=C([H])OC3=C2[H])C(=NO1)C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C#CC([H])([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])N=C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C3([H])[H])C([H])=C1[H]
[H]N(C1=C2C([H])=NN(C2=NC(SC([H])([H])[H])=N1)C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]OC1=C([H])C(O[H])=C(C([H])=C1C1=C(N([H])C(=O)C([H])([H])[H])C(=NO1)C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=NC2=C1N=C(SC1=NC3=C(S1)C(Cl)=C([H])C([H])=C3[H])N2C([H])([H])C([H])([H])N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])[C@]([H])(N(C4=C([H])C([H])=C(N=[N+]=[N-])C([H])=C4[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(N([H])C(=O)C3=NC(C#N)=C([H])N3[H])C(=C2[H])C2=C([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1O[H])C(C#N)=C(C#N)C#N
[H]O[C@@]([H])(C(=O)C1=C(F)C(F)=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1F
[H]OC(=O)[C@]1([H])N(C(=O)C([H])([H])[C@]([H])(SC(=O)C([H])([H])[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=NC2=C1C(=C(N2[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C(=NN1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])N2N=C(C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H]
CC1=CC=C(C(C)=C1)S(=O)(=O)N1CCC(CC1)C(=O)NC1=CC=CC=C1Br
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2[C@]2(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]2([H])C([H])([H])[N+]([H])([H])[H])=C1[H]
[H]C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C(C2=C3N=C(N=C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C1Br
[H]OC([H])([H])C([H])([H])OC1=NC(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C(OC2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC2=NC([H])=C(Br)C([H])=N2)=N1
[H]N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1(C([H])([H])N(C2=C3SC([H])=C(N3N=C2OC([H])([H])[H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C(=NN2C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2F)C(F)(F)F)C([H])=C1[H]
[H]C1=NC(=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C([H])=NC3=C(C([H])=NC4=C3C([H])=C([H])C([H])=C4[H])C2=O)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(Cl)C2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2(C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C(=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])O1)[N+]([O-])=O)C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(Br)C([H])=C([H])C([H])=C1F)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])SSC([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N1N=NN=C1C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C(=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=S)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2C(=C1N([H])[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])[C@@]([H])(C2([H])[H])[C@]1([H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C#N
[H]N1N=NN=C1C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]2([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H]
[H]N(N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C(OC([H])([H])[H])C(=NC2=C([H])C([H])=C(F)C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C(F)C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1F
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=NC(=C([H])S2)C([H])([H])[H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)C([H])([H])O[C@@]1([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C1=NC([H])=C([H])C([H])=C1N([H])C(=O)C2([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]O\C([H])=C1\C(=O)C([H])=C2C(=C([H])[C@]3([H])[C@]4([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]5(OC([H])([H])O[C@@]55OC([H])([H])OC5([H])[H])[C@]4(C([H])([H])[H])C([H])([H])[C@]([H])(O[H])[C@@]3([H])[C@]2(C([H])([H])[H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=NN([H])C1=O)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]N1N=C(C([H])=C1C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C([H])([H])N1C([H])=NC(=C1C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C(=NC2=C(C(=NN12)C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(OC1=C([H])C([H])=C(SC([H])([H])C2=NSC(=N2)C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(SC3=C([H])C([H])=C(OC([H])([H])C4=C([H])C(OC([H])([H])[H])=C([H])C([H])=C4[H])C([H])=C23)C(=O)N([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]C([H])=C1C(=O)O[C@@]2([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C([H])=C(C([H])([H])[H])[C@]21[H]
[H]N1C(=C([H])C([H])=C1C([H])([H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C(Br)=C1[H]
[H]N(C([H])([H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])S(=O)(=O)C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
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[H]N1C(=O)C(N2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C(C1=O)C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
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O\N=C/C1=CC=C2N\C(\C(=N\O)\C2=C1)=C1/C(=O)NC2=C1C=CC=C2Br
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[H]C1=C([H])C(=C([H])C([H])=C1Br)C([H])([H])N1C(=O)C2(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
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[H]N([H])[C@]([H])(C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C(N(N=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)O[H])C1=C([H])C(C2=NC3=C([H])C(=C([H])C([H])=C3N2[H])C(=N[H])N([H])[H])=C(O[H])C(=C1[H])C1=C(N([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C1=C(N=C(O1)C1=C2C([H])=C([H])C(=NC2=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=NC2=C([H])C3=C([H])C(OC([H])([H])C([H])([H])O[H])=C([H])C([H])=C3N([H])C2=N1
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(OC([H])([H])C3=C([H])C(F)=C([H])C([H])=C3[H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=[N+](C([H])=C(S1)C([H])([H])[H])C([H])([H])C1=C([H])C(OP([O-])(=O)OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OP(=O)(O[H])OC([H])([H])[C@](N([H])[H])(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)[C@@]([H])(C1=NN=C(N1C([H])([H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
COC1=CC(CN(CCN2CCCCC2)C(=O)NC2=CC=C(C=C2)C2=CNN=C2)=CC=C1
[H]N([H])C1=NC(=NC(=N1)C#N)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N=C(SC2=C([H])C(I)=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN(C(=O)C2=C([H])SC([H])=N2)C2=C1C([H])=C(Cl)C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]2([H])N3C4=C(OC([H])([H])C3([H])[H])C([H])=C([H])C([H])=C4[C@@]2([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C(C([H])=C2[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])[C@]12[H]
COC1=C(F)C2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=CC=C(C(F)=C3)C3=NC(=CC=C3)N3CCN(CC3)C3CCCCC3)C2=O)C=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C([H])([H])C([H])([H])N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])[C@]([H])(N2C(=NC4=C2C([H])=C([H])C([H])=C4[H])C([H])([H])[H])C3([H])[H])C([H])([H])C([H])([H])N(\C(SC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=N/C#N)C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C1=NC(OC([H])([H])C([H])([H])[H])=NC(=N1)N1C([H])=NC2=C1C([H])=C(C([H])=C2[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C2OC(OC([H])([H])C2=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=NC2=C([H])C([H])=C(N([H])C(=O)C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])=C12)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=O)N(C(=O)C2=C1[H])[C@]([H])(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])[H]
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[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
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[H]OC1=C([H])C([H])=C(\C([H])=C2/OC3=C([H])C([H])=C(O[H])C(OC([H])([H])[H])=C3C3=C2[C@@]2([H])C(=C([H])C(N([H])[C@@]2([H])C([H])=C3[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C(=O)N(C1=C([H])C([H])=C2N=C(C([H])=C(C2=C1[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C(/[H])[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])C1=O
[H]O[C@]([H])(C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
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[H]OC(=O)C([H])([H])N1C2=C(Cl)C([H])=C([H])C([H])=C2C(SC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C([H])([H])[H]
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[H]N(C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])S(=O)(=O)C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N([H])[C@@]([H])(C2([H])[H])C([H])(F)F
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[H]C([H])=C([H])C([H])([H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])N(C(=O)C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C1=NC(=C([H])S1)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])SC(=N2)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]1([H])C(=O)C([H])([H])O[C@@]1([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C3O[C@]([H])(C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])OC3=C([H])C([H])=C2N1[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1C(=O)N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]23C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2([H])[H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
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[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1(C([H])([H])N([H])C(=O)N([H])C2=C(C([H])=C([H])C([H])=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]SC1=NN=C(S1)N([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])[C@@]2([H])N(C([H])([H])C(=O)N([H])C3=C([H])C([H])=C(OC4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])[C@]1([H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])C2=C(N1C([H])([H])[H])C([H])([H])C([H])([H])N([H])C2=O)C1=C([H])C(=C([H])C([H])=C1OC(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@@]2([H])C3=C([H])C([H])=C(C([H])=C3O[C@@]2([H])C1([H])[H])S(=O)(=O)C1=C(Cl)C(Cl)=C([H])C([H])=C1[H]
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[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])([H])[C@@]2([H])C([H])([H])[C@]1([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N([C@]1([H])C(=O)N(C2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C3([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)S1
[H]N([H])C1=NC(=C([H])S1)C1=C(N(C(=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C(=O)N([H])S(=O)(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
CS(=O)(=O)C1=CC=C(C=C1)C(=O)C(=C\C1=CC=C(O)C=C1)\C1=CC=CC=C1
[H]OP(=O)(O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N(C1=NC(Cl)=C([H])N(C1=O)[C@]([H])(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C(=C(OC([H])(F)F)N=C1C([H])([H])[H])C([H])([H])[H]
CCCC1=CC=CC=C1NC(=O)C1=NC2=C(NS(C)(=O)=O)C=CC=C2C(O)=C1
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[H]OC(=O)C1=C(OC(=N1)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N([H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=N2)C([H])=C1[H]
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[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N1C([H])=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
[H]N1C(=S)N([H])C2=C1C([H])=C([H])C(Cl)=C2[H]
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[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC([H])=NC(=C2[H])C2=C(F)C([H])=C(F)C(F)=C2[H])C([H])([H])[C@]1([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C1=C2C([H])=C([H])C([H])=C([H])C2=NC(=N1)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2N=C([H])N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])N(C3=C2C([H])=C(C#N)C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])=C1[H]
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[H]C1=C(C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC1=C(C(=C(C2=C1C(=O)OC2([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])N([H])C([H])([H])C([H])([H])P(=O)(O[H])O[H]
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[H]N([H])C1=C([H])C([H])=C(C([H])=C1F)S(=O)(=O)N([H])C1=NN=C(S1)S(=O)(=O)N([H])[H]
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[H]N(C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C1=C(C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N(C(=O)C2(C1=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C(F)=C(C([H])=C1[H])C1=NC2=C(S1)N=C(C([H])=C2[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C3=C(C([H])=C2[H])C2=C(N=C(N=C2O[H])N([H])[H])C([H])([H])C3([H])[H])C([H])=C1[H])C(=O)O[H]
[H]N(C(=O)C1=C([H])C(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=NOC(=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])F)C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)C1([H])C2=C(OC3=C1C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]O\N=C(/N([H])[H])[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@]([H])(N1C(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(C([H])([H])OC4=C([H])C([H])=C(C([H])=N4)C(F)(F)F)C1([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C([H])C([H])=C(Cl)C([H])=C2N2C1=NN=C2C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C(F)(F)F)=C([H])C([H])=C1OC([H])([H])C(F)(F)F)C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)C1=NN(C(=O)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)C4=C([H])C([H])=C([H])C([H])=C4[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(F)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C2N=C([H])C(=C(N2N=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C2=C(S1)N1C(=NN=C1C([H])([H])N=C2C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]C1=C(N(N=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N1N=NN=C1C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]2([H])N1C2=C(N=C1C1([H])C([H])([H])C1([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C(N([H])C([H])([H])C(=C([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2OS(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=NN1C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C(=N2)C#N)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[C@@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@]([H])(C1([H])[H])[C@@]([H])(OC([H])([H])OC([H])([H])[H])C2([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])[H])C(Cl)=C1[H])C(F)(F)F