[H]C1=C([H])C([H])=C2C(SC(=C2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])OC2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])N1C(=O)N([H])C([H])([H])C1=O)C([H])([H])O[H]
[H]N(C(=O)O[C@@]([H])(C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)C1=NOC(=N1)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N(C([H])([H])C#C[H])C([H])([H])C2=C([H])C([H])=C3N=C(N=C(O[H])C3=C2[H])N([H])[H])C(Cl)=C1[H])C(=O)O[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NN=C(N=N1)C1=C([H])C(O[H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(OC([H])([H])[H])C(=O)N(C([H])([H])C1=C([H])SC([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C(N=C(C([H])=C1C([H])([H])[H])C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1N(C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1=O
[H]N1N=C(N=C1C1=C([H])C([H])=C2OC([H])([H])C([H])([H])OC2=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])N([C@]([H])(C4=C([H])C([H])=C(Br)C([H])=C4[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C3([H])[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C(F)C([H])=C(F)C([H])=C1F)C([H])([H])OC([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)N([H])C1=C(Cl)C(Cl)=C(C([H])=C1S(=O)(=O)N([H])[H])S(=O)(=O)N([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])C1=C(Cl)C(Cl)=C(C([H])=C1S(=O)(=O)N([H])[H])S(=O)(=O)N([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NOC([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C2=C1N(C1=C2C([H])([H])SC2=C([H])C(F)=C([H])C([H])=C12)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)S(=O)(=O)C1=C([H])C([H])=C(Cl)S1
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC(=NS1)C1=C([H])C([H])=C([H])C([H])=C1[H]
OC(CNC1CCN(CC1)C1=NC=NC2=C1C(=CS2)C1=CC=CC=C1)COC1=CC=C(O)C=C1
[H]OC(=O)[C@]1([H])[C@@]([H])(SC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C(=O)N([H])C(C1=O)(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@]2([H])C([H])([H])[H])C(N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])=NC([H])=C2[H])=C(F)C(N([H])[H])=C3C1=O
C\C(CO)=C/CC1=C(O)C=C2OC(=O)C=CC2=C1
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C1=NC(=NC2=C1C(=C(N2C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]ON1C(=O)[C@]([H])(N([H])C(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])=C([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1(C2=NN=C3N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC(N([H])[C@@]2([H])C([H])([H])C([H])([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C1[H])[C@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]\C(=C(\[H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C(C2=C1C(Cl)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3OC([H])([H])C([H])([H])OC3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
CC(C)(C)NC1=C(C#N)C(N)=CC(NC2=CC=C(C=C2)C(N)=O)=N1
[H]C1=C([H])C([H])=C(O1)[C@]1([H])N2C(=O)C([H])([H])N(C(=O)[C@@]2(C([H])([H])OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F)C([H])([H])C(F)(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C#N)C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1F
[H]C1=C(C2=C([H])C([H])=C([H])C([H])=C2N1[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2OC1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C2=C(O[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])OC(=O)N([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2S1
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])N(C(=O)N([H])C2=C([H])C(=C(F)C([H])=C2[H])C(F)(F)F)[C@]2([H])C([H])([H])C([H])([H])[C@]3(C4=C(C#N)C([H])=C([H])C([H])=C4[H])C([H])([H])[C@]23[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)[C@]3([H])[C@]4([H])O[C@@]([H])(C([H])([H])C4([H])[H])[C@]3([H])S2(=O)=O)C([H])([H])C1([H])[H])C(F)(F)F
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])N(C([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2C(OC([H])([H])C1=O)(C1=C([H])C([H])=C(Cl)S1)C1=C([H])C([H])=C(Cl)S1)C1=C([H])C(F)=C([H])C(C#N)=C1[H]
[H]OC(=O)C([H])([H])N1C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O\C(S[H])=N\C2([H])C([H])([H])C2([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C([H])N=C12)N([H])[C@]1([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N=C(N([H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N(C1=NC(Cl)=C([H])N(C1=O)C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C([H])C([H])=C([H])C(C3=NC4=C([H])C([H])=C(O[H])C([H])=C4O3)=C2C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])C1=C([H])C([H])=C([H])C2=C1C(=O)C1=C(N([H])N=C21)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=N1)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=NC([H])=C1F)N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(O1)C([H])([H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C4=C([H])C([H])=C([H])C(OC([H])([H])[H])=C4C([H])([H])C([H])([H])[C@]23[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])S(=O)(=O)OC1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NN=C2C([H])=C([H])C(=NN12)C1=C([H])C([H])=C(C(=O)N([H])C([H])([H])[H])C(Cl)=C1[H]
[H]N(C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C(=O)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N1C(SC2=C([H])C([H])=C([H])C([H])=C2[H])=C2C3=C(C([H])=C([H])C([H])=C13)[C@@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C2([H])[H]
[H]O[C@]1([H])C([H])([H])S[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])O[H]
[H]C1=NC(=C([H])C([H])=C1C#N)N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])[C@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])[C@@](C([H])([H])[H])(C([H])([H])OC3=NC([H])=C(Cl)C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1O[H])C1=C([H])C([H])=C(O1)C(\[H])=C1/SC(=O)N(C1=O)C([H])([H])C(=O)O[H]
[H]C1=NN=NN1C([H])([H])OC1=C(Br)C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C([H])([H])C1=C(OC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(O[H])N=C2C(=N1)C([H])=C(C#N)C(=C2[N+]([O-])=O)C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C(=C1[H])C(=O)N([H])[C@]([H])(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])[C@@]([H])(SC(=O)C2=C([H])C([H])=C([H])N=C2[H])C1([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(N([H])C2=NSN=C2N([H])[C@@]([H])(C2=C([H])C([H])=C3OC([H])([H])C([H])([H])OC3=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(\[H])=C(\C(\[H])=C(/[H])\C(\[H])=C(\C(\[H])=C(/[H])C1=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])/C([H])([H])[H])/C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(N(C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
CC1=CC(=CC=N1)C1=NC(=NN1)C1=CC(=C(Cl)C=C1)N(O)=O
[H]N([H])C(=O)C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@@]([H])(N([H])C(=O)C(C1=C([H])C([H])=C(N=C1[H])N([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NN2C([H])=C(C([H])=NC2=C1C1=C([H])C([H])=C(F)C(Cl)=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C([H])=C([H])C([H])([H])[C@@]12C3=C([H])C(OC(=O)N([H])C4=C([H])C([H])=C([H])C([H])=C4[H])=C([H])C([H])=C3N(C([H])([H])[H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C2C([H])=C([H])C([H])=C([H])C2=NC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=NC(=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])[H])C([H])([H])N(C2=C([H])C3=C(N2C([H])([H])C2=C(C([H])=C([H])C(F)=C2[H])C([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C(=O)[C@@]([H])(N([H])C(=O)C1=C(C(=O)C2=C([H])C([H])=C([H])C([H])=C2N1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C2C([H])=NN(C2=NC(SC([H])([H])[H])=N1)C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(F)C(Cl)=C1[H])C1=C2C([H])=C(N([H])C([H])([H])C3=C(N=C([H])N3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(Br)C2=NC([H])=C1C#N
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#CC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])=O)N([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])[H])C1=C2C(=C([H])C([H])=C1[H])C1=NN([H])C(C3=C([H])SC([H])=C3[H])=C1C2([H])[H]
[H]N1C([H])=C(C#N)C2=C1N=C([H])N=C2C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C#N)C([H])([H])C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C(Cl)=C([H])C([H])=C2Cl
[H]N(C(=O)C([H])([H])[C@]1([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])([H])C([H])([H])N1[H]
[H]N([H])C1=NC(=C(S1)S(=O)(=O)N1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]ON(C([H])=O)[C@@]([H])(C([H])([H])N1C(=O)N(C([H])([H])[H])C(C1=O)(C([H])([H])[H])C([H])([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]N(C1=C([H])C(=O)C(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])=C([H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C1(C(=O)N([H])N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])C1=C(C2=C(N=C([H])N=C2S1)N([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])OC([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC2=C(N=NN2C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C(=N1)C1=C([H])C([H])=C([H])O1
[H]N([H])C([H])([H])C1=NOC(=N1)C1=NN([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]O[C@@](C([H])([H])N([H])C(=O)C1=C(N([H])[H])N(N=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])N(C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N1[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C(Br)C(=N1)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=NC2=C([H])C(=NN12)C1=C([H])C(=NC([H])=C1[H])N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])N=C(C2=C([H])C([H])=C([H])N=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N(C1=O)C([H])([H])C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)N(C1=O)[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C(C(F)=C([H])C([H])=C2[H])C1=O)C([H])([H])[H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C(=O)O[H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C2=C(S1)C([H])=C(Cl)C([H])=C2[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C(N=C=S)=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=CC(NC2=NC(NCCCC3=CNN=C3C)=NC=C2Br)=NN1
[H]OC1=C([H])C2=C(C(O[H])=C1O[H])C1=C(O[H])C(O[H])=C(O[H])C([H])=C1C(=O)OC([H])([H])[C@@]([H])(O[H])[C@@]([H])(OC2=O)[C@]1([H])OC(=O)C2=C([H])C(O[H])=C(O[H])C(O[H])=C2C2=C3C(=O)O[C@@]1([H])[C@@]([H])(O[H])C3=C(O[H])C(O[H])=C2O[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C2N=C(N=C([H])C2=C1[H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C(C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]\C(=C(\[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])[C@@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Br)C([H])=C1[H])C2([H])[H])C([H])([H])F
[H]OC([H])([H])[C@@]([H])(N([H])C1=NC2=C(N=C([H])N2[C@]2([H])O[C@]([H])(C3=NN=NN3C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])[C@@]2([H])O[H])C(=N1)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NN=C(O1)N([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])[S+]([O-])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C(=C2O[C@@]([H])(SC2=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
CC1=CC=C(CCOCCCC2=CC=CC(CCCOCCC3=CC=C(C)C=C3)=[N+]2C)C=C1
[H]N1N=C(N=C1C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C([H])=C([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2O1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3N=C(OC3=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=S)N(C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])[C@]([H])(OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=O)N2C(=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])[C@@]([H])(C2([H])[H])C1([H])[H]
[H]OC(=O)C1=C([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
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[H]C1=C(N(N=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=NC2=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C2([H])[H]
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[H]OC(=O)[C@@]([H])(N1C(=S)S\C(=C(\C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=N[C@](C2=C([H])C([H])=C(F)N=C2[H])(C2=C([H])C([H])=C(F)C([H])=C2[H])[C@]1([H])C([H])([H])[H])C1=NC([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C1=NC(=C(O1)C1=C([H])N2C(=NN=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=C(F)C([H])=C(F)C([H])=C1F
[H]N([H])C1=NN([H])C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])C([H])([H])C2=C([H])C(I)=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@@]1(O[H])C([H])([H])[H]
[H]N(C1=C(SC2=NC(=C([H])S2)C([H])([H])C([H])([H])[H])C([H])=C2C(=O)OC([H])([H])C2=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])C4=C(C5=C(N4C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])C5([H])[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C(F)=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(N=C(C([H])=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])C(=C(\C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])\C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C(Br)=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C(=C([H])C([H])=C1F)C(=O)C([H])([H])C([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C2([H])[H]
[H]N(C1=NC(=NC(=N1)C#N)N([H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(=NC(=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])N1C([H])=NC2=C1C([H])=NC([H])=C2[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]OC([H])([H])[P@@](=O)(O[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])C1(C(=O)N([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
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[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C2C([H])=NN([H])C2=C1[H]
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[H]N1C([H])([H])[C@@]2([H])C([H])([H])N(C3=C([H])N=C([H])C(OC([H])([H])C([H])([H])[H])=C3[H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]O[C@]([H])(C(=O)N([H])C(C(=O)OC([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N([H])C1=N[C@@](C(=O)N1C([H])([H])[H])(C1=C([H])N(N=C1[H])C([H])([H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1F
[H]C1=NN(C2=C1C(=NC([H])=N2)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C3=C(O2)C(C#N)=C(C([H])=C3[H])C(F)(F)F)C(OS(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F)=C1[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C(=O)N(C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=N/OC(=O)C([H])([H])OC1=C(Cl)C([H])=C(Br)C([H])=C1[H])\C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)N([H])[C@]([H])(C#CC1=C([H])N=C(OC2=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])S1)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C(N([H])C([H])([H])[H])=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)[C@@]([H])(C(=N\OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])\C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C2C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2=C1[H]
[H]OC(=O)[C@]([H])(N([H])C1=C(C#N)C(=NC2=C([H])C([H])=C(F)C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(F)(F)F
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C1=C2C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=NN1[H])C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H]
[H]O[C@@](C([H])([H])N1C2=C(OC([H])([H])C1([H])[H])C([H])=C([H])C([H])=C2[H])(C([H])([H])C(C1=C(OC([H])([H])[H])C([H])=C([H])C(F)=C1[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]\C(=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C1=NN=C(O1)C1=C([H])C([H])=C([H])S1
[H]OC(=O)C([H])([H])[C@@]([H])(C([H])=C(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1[H])S(=O)(=O)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])[N+]([O-])=O
[H]C1=NN(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C2(C1([H])[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])N3C([H])=C(Cl)C([H])=C([H])C3=N1)C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])N1C(=NC([H])=C1[N+]([O-])=O)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C(=O)N([H])C2=NC([H])=C([H])C(=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(SC2=NN3C([H])=C([H])C([H])=C3C(=N2)N([H])C2=NN([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C(=O)C(=C([H])C2=C([H])N=C(N=C12)N([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(SC([H])([H])C2=NC(=C(S2)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(Cl)=C1[H]
[H]N(C1=NC([H])=NC2=C1C([H])=C(N=C2[H])N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1F)C1=NC2=C(S1)C([H])=C(Cl)C([H])=C2[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1N=C(C2=C(N=NS2)C([H])([H])[H])\C(=C(/[H])C2=C([H])N(C3=C2C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])[H])C1=O
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=N1)C(=O)C1=C([H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(OC2=C(F)C(=C(F)C(=N2)N2C([H])([H])C([H])([H])N(C([H])([H])C(=O)N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C2=C([H])C([H])=C(N=C12)C1=C([H])C([H])=C2OC([H])([H])OC([H])([H])C2=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C([H])([H])N(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])OC2=C([H])C(O[H])=C([H])C(O[H])=C2C([H])([H])[C@]1([H])O[C@]1([H])O[C@@]([H])(C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@@]1([H])O[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(Cl)C(=C1[H])C(F)(F)F)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C(=C2[H])C(=O)N([H])C([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(I)N=C3N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N2[C@]([H])(C(=O)N([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(S1)N1C(=NC([H])=C1C([H])([H])[H])C(=N2)N([H])C([H])([H])C([H])([H])N([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C2(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])S[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]ON([H])C(=O)[C@@]([H])(OC([H])([H])C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C([H])=C2[H])C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(N=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])C([H])=[N+]1[O-]
[H]N(C(=O)C1=C([H])C([H])=C2N=C([H])C([H])=C([H])C2=C1[H])C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C(Cl)=C3[H])C([H])=C2C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C3=C2C([H])=C(C(=O)C([H])([H])[H])C(=O)O3)=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])C2=C([H])C(=C([H])C(Br)=C2OC1=O)C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C(=C1[H])N1C([H])=NC2=C(C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1=O)C([H])([H])[H]
[H]N(C(=O)C1=C(N(C2=C([H])C(=C([H])C([H])=C12)C1=N[C@@]([H])(C([H])([H])[H])C([H])([H])O1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])C(F)=C1[H]
[H]N(C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])SC1=C(C([H])=C([H])C(=C1[H])C1=NN(C2=C1C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@]1(O[H])OC(=O)C(=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]C1=C(C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C(F)=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C(N(\N=C(/[H])C2=C([H])C([H])=C(S2)C([H])([H])[H])C1=S)C1=C([H])N=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C(OC2=C([H])C([H])=C(Cl)C([H])=C2Cl)C(=O)C([H])=C(O1)C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C([H])C(=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C(=N1)N([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C1=NC([H])=NC(=N1)N([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(F)=C(F)C([H])=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(=O)C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=N1)C1=C(ON=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])P(=O)(O[H])O[H])C(=O)O[H]
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[H]N(C(=O)C([H])([H])SC1=NC([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C(=C([H])C([H])=C1Cl)S(=O)(=O)[C@]12C3=C(F)C([H])=C([H])C(F)=C3OC([H])([H])[C@@]1([H])[C@]([H])(C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N1C([H])=C2C(=C1\C([H])=C1/C(=O)N([H])C3=C([H])C([H])=C([H])C(=C13)C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])OC2=O
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@@]([H])(C(\[H])=C(/[H])C2=C(C([H])=C(N=C2C([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N(OC([H])([H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C(=O)C(Br)=C(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2F)C([H])=C1C([H])([H])[H]
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[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C#CC([H])([H])OC([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H]
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[H]OC(=O)C([H])([H])C1(C([H])([H])S[C@@]([H])(C2=C([H])C(\C([H])=C(/[H])C3=NC4=C(SC([H])([H])C4([H])[H])C([H])=C3[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N1C([H])=C([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N3C4=C5C(=C([H])C([H])=C([H])C5=C([H])C([H])=C4[H])S3(=O)=O)C([H])([H])C2([H])[H])C(F)=C1[H]
[H]N(C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C2=C(N(N=C2[H])C2=C(F)C([H])=C([H])C([H])=C2F)N(C1=O)C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
O=C(NCC1CCCCC1)C1=C(NC(=O)C2=C3C=CC=CC3=CC=C2)C=NC=C1
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[H]N1C(=O)N(C(=O)\C1=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]N(C(=O)N([H])[C@]1([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N(C1=O)C([H])([H])C(=O)N(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1(N=N1)C(F)(F)F
[H]C1=C([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[N+](=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C(F)C([H])=C2C(=O)C3=C(N([H])C2=C1[H])C([H])=C([H])C([H])=C3[H])C(C1=C([H])N=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(N=C(C(F)=C1[H])C1=C(F)C([H])=C([H])C([H])=C1F)C(=O)C([H])([H])C1=C([H])N=C([H])C([H])=C1[C@@]1([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
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[H]N([H])C1=C(Cl)C([H])=C(C(=O)N([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C(N([H])S(=O)(=O)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
N[C@H](CC1=CC=CC(Cl)=C1)C1=NC2=CC=C(C=C2C(=O)N1)C1=CNN=C1
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[H]N1C([H])=C([H])C2=C(C([H])=C([H])C([H])=C12)C1=C([H])C(=C2N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]([H])(C2=C1Cl)C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C2=C([H])C([H])=C(Cl)C([H])=C2S1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C(=NN2C([H])(C([H])([H])[H])C([H])([H])[H])C#CC1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C(S1)C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C3=C([H])C4=C(O3)C([H])=C([H])C([H])=C4[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
CN(C(C)=O)C1=C2C=CC(=CC2=NC=C1C#N)C1=CC=C(C=C1)S(C)(=O)=O
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)O[H])C1=C([H])C(C2=NC3=C([H])C(=C([H])C([H])=C3N2[H])C(=N[H])N([H])[H])=C(O[H])C(=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(F)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C(C([H])=C12)S(=O)(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C([H])=C(N([H])C([H])([H])C([H])([H])Cl)C([H])=C12)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]O[C@]1([H])N(C(=O)C([H])([H])C([H])([H])C1(F)F)C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C(=O)N1C([H])([H])C2=C(C(=NC(=N2)C2=C([H])C([H])=NC([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C1=NC(OC([H])([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=NC([H])=C2Cl)C([H])=C1[H]
[H]N([H])C1=C(C([H])=NN1C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]ON([H])[C@]1([H])N([H])C([H])([H])[C@](N([H])C([H])([H])[C@@]([H])(O[H])[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C(F)=C([H])C(F)=C2[H])(C2=C([H])C([H])=C([H])C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C1=C([H])C(=S)C2=C([H])C([H])=C(F)C([H])=C2O1
[H]OC1=C(Br)C(Br)=C(Br)C([H])=C1OC1=C(O[H])C(Br)=C(Br)C(Br)=C1Br
[H]OC1=C([H])C(O[H])=C(C([H])=C1Cl)C1=C(SN=N1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)N(C2=C([H])C([H])=C(Cl)C([H])=C12)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C2=NC3=C([H])C([H])=C([H])C([H])=C3S2)C([H])([H])C1([H])[H]
[H]O[C@]1(OC(=O)C(=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2Cl)=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C(=C([H])N2C(=O)N(C([H])([H])[H])C([H])([H])[H])C(=O)C1=C2N(C([H])=C1[H])[C@]([H])(SC2([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(N([H])C([H])([H])C3=C([H])C([H])=C([H])N=C3N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C2=N1)C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C2([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C(=O)[C@]([H])(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C2=C(C(=NN2C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])C1=C([H])C(F)=C(C(F)=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
COC1=CC=C(CNC(=O)C2=C(N)C3=C(C)C(Cl)=C(C)N=C3S2)C=C1
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N([H])C2=C(N=C(S2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])C1([H])[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C(N([H])C(=O)C3=C([H])C([H])=C([H])C(=C3[H])C(F)(F)F)=C([H])C([H])=C2C([H])([H])[H])C([H])=NN1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C(OC1=C([H])C([H])=C(OC2=C([H])C(=C([H])C(F)=C2[H])C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2F)C(F)(F)F)C([H])=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C2=C([H])N(N=C12)C1=C([H])C([H])=C(C(=C1[H])C(F)(F)F)C([H])([H])N([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]\C(C1=C([H])C([H])=C([H])C([H])=C1OC(=O)C([H])([H])[H])=C1/C(=NC([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N([H])C1=NC(N([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1C(=O)C1=C(F)C([H])=C([H])C([H])=C1F
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C(=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(C([H])([H])C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1C(F)(F)F)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2Cl)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)C1=C(Cl)C2=C(S1)C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C(C([H])([H])[H])(C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H])C1=C(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C(S1)C([H])([H])OC([H])([H])C2([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C2=C(N=C(N=C2C([H])=C1[H])N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(SC(=NC1=O)N([H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N=C(S1)N([H])C1=C([H])C(=C([H])C([H])=N1)N1C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H]
[H]N(C(=O)OC1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(N([H])C([H])=C2C([H])([H])C2=C([H])C([H])=C(C([H])=C2OC([H])([H])[H])C(=O)N([H])S(=O)(=O)C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])SC(=O)C([H])([H])[H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C2=C([H])C(=C([H])C3=C2N1C(=O)C([H])([H])C3([H])[H])C(=O)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C2OC([H])([H])C(=O)N([H])C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)C([H])([H])OC3=C([H])C([H])=C(C([H])=C23)C2=C([H])C([H])=C([H])O2)C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C(=NC2=C([H])C(=C([H])C([H])=C12)C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])C(=O)C1=C([H])C([H])=C([H])S1
[H]N(C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2[C@@]([H])(N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)N([H])C2=C1C([H])=C([H])C([H])=C2C([H])([H])[H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])[C@]1(N(C(=O)N([H])C1=O)C([H])([H])[H])C2([H])[H]
[H]N(C(=O)C1=C(ON=C1C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(OC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C2N=C([H])N([H])C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@@]2([H])C([H])([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C2=C(O1)C([H])=C([H])C(Cl)=C2[H])[C@@]1([H])[C@@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C([H])C2=C(S1)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]21[H]
[H]N(C1=NC(=C([H])N2C1=NC([H])=C2C1=C([H])N([H])N=C1[H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C2=NC(=C([H])C([H])=C2C(=C1[H])C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C([H])[C@]4([H])OC(=N[C@]4([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]OP(=O)(O[H])OC([H])([H])[C@](N([H])[H])(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])=C1[H])C([H])([H])[H]
[H]SC1=NN=C(N1N([H])[H])C1=C(C([H])=C(S1)N([H])C(=O)C([H])([H])Cl)C([H])([H])[H]
[H]C1=NC(=C([H])N1C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=NC(=C([H])C([H])=C1[H])[C@@]1([H])OC([H])([H])C([H])([H])N(C2=NN=C(S2)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C2/C(=O)N([H])N(C2=O)C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])=C1OC([H])([H])[H]
COC1=CC(CN2CCC3(CCN(CC3)C(=O)CNC(C)=O)OC3=C2C=CC=C3)=CC=C1
[H]OC12C(=O)C(=C([H])C1([H])C13OC4(OC([H])(C1([H])C([H])=C(C([H])([H])OC(=O)C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C2([H])[H])C(O4)(C(=C([H])[H])C([H])([H])[H])C([H])([H])C3([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C(C2=NC3=C(N2[H])C([H])=C([H])C(=C3[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C12)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(O[H])=C([H])C(=C2O1)C([H])([H])C([H])=C([H])[H]
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[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])\N=C2/C(=O)N([H])C3=C([H])C([H])=C([H])C(C([H])=C(C([H])([H])[H])C([H])([H])[H])=C23)C([H])=C1[H]
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[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@@]1([H])C([H])([H])N(C(=O)C([H])=C([H])[H])C([H])([H])C([H])([H])C1([H])[H]
OC(=O)CC1=CC=C(C=C1)N(CC1=CC=CC=C1)CC1=CC=C(OC2=CC=CC=C2)C=C1
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[H]C1=C([H])C(=C([H])C(C#N)=C1[H])C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
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[H]N(C(=O)C1=NOC2=C1C([H])([H])C([H])([H])C1=C2C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
COC(=O)NCCC1=CNC2=CC=C(OCC3=CC=C(C=C3)C3=CC=CC=C3)C=C12
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=NC2=C(C([H])=C([H])C([H])=C2[H])[C@@]1([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC[C@H]1O[C@H](OCCC2=CC=CC=C2)[C@H](NC(=O)CCCN)[C@H](OCC2=CC3=CC=CC=C3C=C2)[C@@H]1O
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=NC([H])=C2S1
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[H]OC1=C([H])C([H])=C2SC([H])([H])[C@@]3([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])O[C@@]3([H])C2=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=C(C2=C1N=C([H])N=C2N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C1(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])C3=C4C([H])=C([H])C([H])=C([H])C4=NC(=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(N(C#N)C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)O[C@@]([H])(C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])N([C@]([H])(C4=C([H])C([H])=C(C([H])=C4[H])C(F)(F)F)C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
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[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C(=O)N2C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC1=NC(=C(N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SN=N1)C([H])([H])C1=C([H])C(F)=C(C([H])=C1[H])C(F)(F)P(=O)(O[H])O[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl)C1=C([H])C(=NN1C1=NC([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C([H])([H])N(C(=O)[C@]([H])(C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(C([H])([H])N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]O[C@]1(C2=C(C([H])=C([H])C([H])=C2[H])N2C(=O)[C@](N([H])[C@]12[H])(C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2N2C(=O)C3=C(N=C12)C([H])=C([H])C([H])=C3[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(C2=C([H])C([H])=C([H])O2)=C(C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=NC2=C1N=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1=NN=C2C([H])=C([H])C(=NN12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(O[H])=C(C2=C1C(=O)C([H])=C(O2)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C(=O)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(N([H])C1=C(C#N)C([H])=C([H])C([H])=C1[H])C(=N\C1=C([H])C(Cl)=C([H])C([H])=C1[H])\C(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C(C([H])=C([H])C([H])=C2[H])C1=O)C(F)(F)F)[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])C1=C([H])SC(=N1)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC1=C([H])C(F)=C([H])C([H])=C1C1=C([H])C([H])=C(O1)C(\[H])=C1/SC(=O)N([H])C1=O
[H]OC1=NC2=C([H])C(Cl)=C(C([H])=C2C(OC([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]2([H])[H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=NN=C(S1)C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])[C@]([H])(N([H])C(=O)C(\[H])=C(/[H])C4=C([H])C([H])=C(C([H])=C4[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2C(=C1[H])C(=O)C(=O)C1=C2C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2=O)C([H])([H])C1([H])[H]
[H]OC(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])(P(=O)(O[H])O[H])P(=O)(O[H])O[H]
[H]N([H])C1=C([H])C(OC([H])([H])C2=NC([H])([H])C([H])([H])N2[H])=C(C([H])=C1Cl)C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=N1)N=C(N(C2=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(C(F)=C1[H])C(F)(F)F)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C(SC([H])([H])C2=NC([H])=C(O2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S1
[H]N(C(=O)[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C(SC([H])([H])C2=NC([H])=C(O2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S1
[H]OC([H])([H])C1=C([H])C(=C([H])N1C([H])([H])[H])N(C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(N([H])C2=NC(=C([H])S2)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C#N
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C(N([H])C2=NC([H])=NC(N([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2[H])=C1[H])C([H])([H])[H]
[H]OC1=C(F)C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])=C1F
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C2=NC(=NC(=C2[H])C([H])([H])[H])N(C2=C(Br)C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1[H]
[H]O[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])N(N=N1)C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=NC(=N2)N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C#C[H])N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N3N=NC(=C3[H])C([H])([H])C([H])([H])C([H])([H])\N=C(/N([H])[H])[N+]([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C(=NC(Cl)=C1[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C(N=C(O1)C1=C2C([H])=C([H])C(=NC2=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N1C2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])[C@]2(C1([H])[H])C([H])([H])C1([H])N(C([H])(C3=C(Cl)C([H])=C([H])C([H])=C3[H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])[C@@]([H])(C([H])([H])C1([H])[H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])N(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(N([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C(N([H])C2=C([H])C(OC([H])([H])[H])=NC(=N2)N2C([H])=NC3=C2C([H])=C([H])C([H])=C3[H])=C1[H])C([H])([H])[H]
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C2=NC=CN2C)C(=N1)N1CCOC[C@@H]1C
[H]N([H])C1=C(N=C(N=C1N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C#N)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(Cl)=C([H])N=C(N([H])C([H])([H])C(F)(F)C2=NC([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C1=NC([H])=C([H])C([H])=C1N1N=NN=C1[H]
[H]O[C@]1(OC(=O)C(=C1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C(N=C(S1)C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=N1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C3=C([H])C4=C(OC([H])([H])O4)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC(=O)C1=C([H])C(Br)=C([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=NN2C(N=C([H])C([H])=C2C2=C([H])C(OC([H])([H])C3([H])C([H])([H])C3([H])[H])=C(OC([H])(F)F)C([H])=C2[H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(OC([H])([H])[C@@]3([H])OC4=C(C([H])=C([H])C([H])=C4[H])N(C([H])([H])[H])C3([H])[H])C([H])=C2Cl)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N([H])C1=C(C2=C(N1[H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C1=C([H])C([H])=C([H])C([H])=N1
[H]OC(=O)C1=C(OC2=C([H])C([H])=C(C([H])=C2N([H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C(F)(F)F)C([H])=C([H])C([H])=C1F
[H]N1C(=O)C2=C(N=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1S2)C1=C([H])C(Cl)=C([H])C(F)=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N1C(=O)N(C2=C([H])SC(=N2)C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C2=C(F)C([H])=C([H])C([H])=C12
[H]C1=NN(C([H])=C1[H])C(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC1=C2O[C@@]3([H])C4=C(C5=C([H])C(N([H])C(=N/C([H])([H])C6=C([H])C([H])=C(Cl)C([H])=C6[H])\N([H])[H])=C([H])C([H])=C5N4[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(Cl)N=C1OC([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2N(C([H])([H])[H])C([H])([H])[H]
[H]N1[C@]([H])(SC([H])([H])[C@@]1([H])C(=O)C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)[P@](=O)(OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C([H])=C(Cl)C([H])=C12)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)N(C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC1=NC(=C(N1[H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]OC1=C([H])C([H])=C2O[C@]([H])(C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2=C1C([H])([H])C([H])=C([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])N(C(=O)C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
CC(SC1=NN2C(C=C1)=NN=C2C1=CC=CS1)C1=NN=CO1
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C(\[H])=C(\[H])[C@@]([H])(C#CC([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1C([H])([H])[H]
COC1=CC=C(C=C1)C1=CC(=O)C2=C(OC)C=C(OC)C=C2O1
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C2N=C(C([H])=C(C2=C1[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C(=C1[H])N(C([H])=C(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])N(C1=C([H])C([H])=C2N=C(N(C2=C1[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C(=C([H])C2=C1[H])C(=N[H])N([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C2=C(N([H])C1=O)C([H])=C([H])C([H])=C2[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])[C@@]1([H])C2=C(OC([H])([H])C1([H])[H])C([H])=C(C([H])=C2[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[N+]([H])([H])[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C3=C(C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C(=O)C1=C(C(=NC2=C([H])C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C(Br)=C([H])C([H])=C2N1[H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])N1C2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])[C@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]12[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=NN23)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=C3N=C(N([H])C3=C2[H])C2=C(N([H])C([H])([H])[C@@]([H])(O[H])C3=C([H])C([H])=C([H])C(Cl)=C3[H])C([H])=C([H])N([H])C2=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C3=C1OC([H])([H])C3([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=NC2=C(C([H])=C([H])C(=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]3([H])C4=C(C([H])=C([H])C(=C4[H])C([H])([H])[H])C([H])([H])[C@]23[H])C1([H])[H]
[H]N(C1=NC([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])SC(=N1)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]O[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=NN([H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2F)[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=C([H])C2=C1N=C(N=C2[H])N([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(F)(F)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(Cl)C([H])=C1C(=O)N([H])C1=C2N=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])O[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C3=C(C([H])=C2[H])C(=C([H])C(=O)O3)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])N(C1=NC(=NC2=C1C([H])=C([H])C([H])=C2[H])N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1=C(C([H])=NC([H])=C1[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C4N([H])C([H])=C([H])C4=C3C([H])([H])C([H])=C([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C([H])=C([H])N([H])C1=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])OC([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
OC1=CC=C(C(=O)\C=C\C=C\C2=CC=C(Cl)C=C2)C(O)=C1
[H]OC1=C(C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])N1C([H])([H])[H]
[H]N1C2=C(C([H])=C(Cl)C([H])=C2[H])C2=C1C([H])([H])[C@@]([H])(C([H])([H])C2([H])[H])[C@](C(=O)OC([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N(C1=C([H])C([H])=C(Cl)C(=C1Cl)C([H])([H])OC1=C2N=C(C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C(N([H])[H])C([H])=C2N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]\C(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C1/N(C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3N=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C2N(C(SC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C(=C3[H])[N+]([O-])=O)=NC2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=C(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C#CC2=C(Cl)C([H])=C([H])C(=C2[H])C2=NN(C3=C2C([H])([H])N(C([H])([H])C3([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])=O
[H]N([H])C1=NC([H])=NC2=C1N=C(SC1=NC3=C(S1)C(Cl)=C([H])C([H])=C3[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(Br)C(O[H])=C([H])C(OC([H])([H])[H])=C2O1
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2N(C(=C3[H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C([H])C2=C([H])C3=[N+](C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C31
[H]N(C1=C([H])C([H])=C(C([H])=C1[N+]([O-])=O)[N+]([O-])=O)C([H])([H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C(O1)C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N(C2=C([H])C([H])=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C2C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
CC1=CC=C(C(C)=C1)S(=O)(=O)N1CCC(CC1)C(=O)NC1=CC=CC=C1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C2C(=O)C(=O)N([H])C(=O)C2=C1[H]
[H]C([H])=C([H])C1=C([H])C([H])=C2C([H])=C([H])N(C2=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=NN([H])C([H])=C3C3(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]([H])(O[H])[C@]1([H])C(=O)N(C2=C([H])C([H])=C(OC([H])([H])C3=C4C([H])=C([H])C([H])=C([H])C4=NC(=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(N([H])C(=O)C2=NN=C(O2)N([H])C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N2C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N(C(=O)N([H])[C@](C1=C([H])C([H])=C(Cl)C([H])=N1)(C1=C([H])C(F)=C([H])C(OC(F)(F)C([H])(F)F)=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])C1(F)F
[H]OC([H])([H])[C@@]([H])(O[H])C([H])([H])OC1=C([H])C([H])=C(\C([H])=C2/S\C(=N/C([H])(C([H])([H])[H])C([H])([H])[H])N(C2=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]ON([H])C(=O)C1=NN2C(=N1)C(O[H])=NC1=C([H])C(Cl)=C([H])C([H])=C21
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[H]OC(=O)C1=C([H])SN=C1[H]
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[H]N(C(=O)[C@@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC([H])=C1[H])C1=C([H])C([H])=C(N([H])C(=O)[C@]2([H])[C@]3([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C3([H])[H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])SC([H])=C2[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(OC([H])([H])[H])=C(N([H])C3=NN4C(=C([H])C([H])=C4C4=C([H])C([H])=C([H])C([H])=C4N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])=N3)C([H])=C2F)C([H])([H])C1([H])[H]
[H]OC1=C([H])C(C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(C#CC1=C2N=C(N(C2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])=N1)C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(N=C(O1)C1=C2C([H])=C([H])C(=NC2=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C([H])([H])N([H])[H]
[H]N([H])C(=O)C1=C(N([H])[H])C2=C(S1)N=C(C([H])=C2C(=O)OC([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C3=C(C#N)C(=NC(N([H])[H])=C13)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]([H])(O2)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C2C([H])=C(Cl)C([H])=C([H])C2=NC(=N1)C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])C1=C(C(=O)OC([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]([H])(C2([H])[H])C1([H])[H]
[H]OC(=O)C1=C([H])C(OC([H])([H])C([H])([H])[H])=C2C([H])=C(C([H])=C([H])C2=N1)C1=C([H])C([H])=C(OC([H])([H])C2=C(ON=C2C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=C(C(=O)C(=O)N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(C(=O)N3C([H])([H])C([H])([H])C([H])(C([H])([H])C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])C3([H])[H])=C(Cl)C([H])=C12
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=C([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NN([H])C2=C1C(=NC([H])=C2[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])N1N=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C(=O)[C@@]12O[C@@]([H])(O[C@]1([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])[C@]([H])(F)C4=C([H])C(=O)C([H])=C([H])[C@]4(C([H])([H])[H])[C@@]3(F)[C@@]([H])(O[H])C([H])([H])[C@]21C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])OC([H])([H])[H])C([H])([H])C(=O)N(C1=C(C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]C1=NC(=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=C([H])N=C4C([H])=C([H])C([H])=C([H])C4=N3)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(S1)C([H])=C([H])C(=C2[H])N1C(=O)O[C@@]2(C1([H])[H])C([H])([H])[N@]1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])S[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])OC2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([C@]1([H])C(=O)[C@@]2([H])[C@@](C([H])([H])[H])(C([H])([H])C([H])([H])[C@@]3([H])C(=O)O[C@]([H])(C4=C([H])OC([H])=C4[H])C([H])([H])[C@]23C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=NC2=C([H])C(Cl)=C([H])C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(Cl)C([H])=C2C(=C1C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(C3=C(N(C4=C([H])C([H])=C(C([H])=C34)C(=O)C3=C([H])C([H])=C([H])O3)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C3=C2C2=C([H])N(N=C2C([H])([H])C3([H])[H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=N1)C1=NC(=NO1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC(C)[C@H]1CN(CCN1)C1=CC=CC(=N1)C1=NNC2=C1C=CC=N2
[H]C1=C([H])C(Cl)=C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])N([C@]([H])(C4=C([H])C([H])=C(C([H])=C4[H])S(=O)(=O)C4=C([H])C5=C(OC([H])([H])O5)C([H])=C4[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C3([H])[H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]N1C(=O)S\C(=C(/[H])C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C1=O
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C(Cl)=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C2=C(N([H])C3=C2C([H])=C([H])C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C1(N([H])C(=O)C2=C([H])C3=C(N(C2=O)C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H])C(F)(F)F
[H]N1C2=C([H])C([H])=C(F)C([H])=C2C2=C1C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=NC3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H]
[H]N=C1N(C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C(=O)N1C([H])([H])C([H])(OC2=C(C([H])=C([H])C([H])=N2)[C@@]2([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])[C@@]1([H])N(C2=NC3=C(N([H])C([H])([H])N3C([H])(C([H])([H])[H])C([H])([H])[H])C(=N2)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(SC([H])([H])C([H])([H])[H])N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N=C(N([H])C1=C([H])C(N([H])N([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=NN=C(N1C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C2N(C(=O)C([H])=C(C3=C([H])C(Cl)=C([H])C([H])=C3[H])C2=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)[C@]([H])(C1=C(C(=O)C(=C(C1=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC(=O)C([H])([H])[H]
[H]OC(C1=C([H])SC(=C1[H])C([H])([H])[H])(C1=C([H])SC(=C1[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[N+]2(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C2C([H])=NN(C2=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])S1)C1=C(C#N)C(SC([H])([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])=NC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C1=NC(=NN(C1=O)[C@]([H])(C([H])([H])OC([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=C(C([H])=C1Cl)C(F)(F)F
[H][C@]12CNCc3ccc(C)c(Cc4c(O)c(O)ccc14)c23
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])SSC(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C([H])C(C3=NN=C(O3)SC([H])([H])C#CC([H])([H])OC(=O)C3=C([H])C([H])=C(C([H])=C3[H])N(C([H])([H])[H])C([H])([H])[H])=C2C([H])=C1[H]
[H]N(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=NC2=C(C([H])=C([H])C(=C2[H])S(=O)(=O)N([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]12C(=O)O[C@]([H])(C([H])([H])[H])[C@@]1([H])[C@@]([H])(C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C2([H])[H]
[H]N1C([H])=C(N=C1[C@]1([H])N([H])C(C2=C(C3=C([H])C([H])=C([H])C([H])=C3S2)C1([H])[H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C3=C([H])C([H])=C([H])C([H])=C3C3=C2C([H])([H])N(C([H])([H])C([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@](N1C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H])(C(=O)OC1([H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])S(=O)(=O)C1=C(OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C(=C(N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2([H])OC([H])([H])C([H])([H])O2)C([H])=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])[H]
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[H]C([H])=C([H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
[H]ON(C([H])=O)[C@@](C([H])([H])[H])(C([H])([H])[C@@]([H])(C1=NC([H])=C(F)C([H])=N1)C([H])([H])[H])C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C2=C(Cl)C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1SC(=S)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[N+]([O-])=O)[N+]([O-])=O
[H]N([H])C1=NC(=O)\C(N1[H])=C1\C2=C(N([H])C([H])=C2Br)C(=O)N([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])C([H])([H])OC(=O)[C@]2([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=N1
[H]OC([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[C@]1([H])N=C([H])N=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])SC1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC1=NC2=C(C([H])=C3C(N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@]3([H])C([H])([H])[H])=C2[H])C(=C1[H])C(F)(F)F
[H]N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=NC(=C(N2[H])C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])C2=C([H])C([H])=C3OC([H])([H])O[C@]3([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2O1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])[H])=C2F)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1(C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]\C(=C(/C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])OC1=C(C([H])=C([H])C([H])=C1[H])C1=C(N([H])C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N1C([H])=C([H])C2=C([H])C([H])=C(C([H])=C12)C1=NC([H])=C(N=C1[H])N1C([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])[C@]1([H])C2([H])[H]
[H]OC(=O)C(\[H])=C(/[H])\C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N(C1=NC([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(SC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=[N+](C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]OC1=NC([H])=NC2=C1N([H])C([H])=C2[C@@]1([H])N([H])[C@]([H])(C([H])([H])O[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])C(=O)N([H])C1=C(C([H])=C(S1)C#CC1=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)OC([H])([H])[H])=C1[H])C(=O)N([H])[H]
[H]N(C(=O)O[C@]1([H])[C@]([H])(C2=C(F)C(=C(F)C([H])=C2N([H])C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1N([H])C([H])=C2[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
CCCN1C(C)=C(C(O)=O)C(=C1C1=CC=C(Cl)C=C1)C1=CC=CC(=C1)N1CCN(CC1)C1=CC=C(NS(=O)(=O)C2=CC=C(N[C@H](CCN(C)C)CSC3=CC=CC=C3)C(=C2)[N+]([O-])=O)C=C1
[H]\C(=C(\C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])ON=C3C4=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C4OC([H])([H])[C@@]23[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2S[C@@]([H])(C1=O)C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C(SC([H])([H])C2=NC(=C([H])S2)C(=O)N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])S1
N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CC[C@@H](C1)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](C(=C)C(N)=O)C1=CC=CC=C1
[H]OC(=O)C([H])([H])C1(C([H])([H])S[C@@]([H])(C2=C([H])C(\C([H])=C(/[H])C3=NC4=C(S3)C([H])=C([H])C(Cl)=C4[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C(C2=C(N3C([H])([H])C([H])([H])N([H])C([H])([H])C3([H])[H])C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3N=C12)C([H])([H])[H]
[H]N(C1=NC(=C([H])S1)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])[C@]2([H])C([H])([H])N(C(=O)C3=C([H])C(F)=C([H])C([H])=C3[H])C([H])([H])[C@]12[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C(C#CC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C([H])C([H])=C1OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=NC(=C(N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N(C(=O)OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]([H])(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C(O[H])C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N1C(=NN2N=C([H])C3=C([H])C([H])=C([H])C(=C23)C([H])([H])[H])N([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(F)=C(C([H])=C1[H])N(C(=O)C1=C(ON=C1C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]12C([H])([H])C([H])([H])[C@@](C3=NC4=C(N3[H])C3=N[C@]([H])(C([H])([H])C5=C([H])C([H])=C([H])C([H])=C5[H])C([H])([H])N3C(=O)N4C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N(C1=NN=NN1C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C(F)C(F)=C([H])C([H])=C1[H]
[H]N1C(SC([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=NC2=C([H])C(Cl)=C(C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]SC([H])([H])[C@@]([H])(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S([O-])(=O)=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C(Cl)N=C23)N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])[C@@]1(N([H])C([H])([H])[C@]([H])(O[H])[C@]1([H])O[H])C1=C([H])N([H])C2=C1N=C([H])N([H])C2=O
[H]C1=C(SC2=C1C([H])([H])[C@]([H])(OC([H])([H])[H])O[C@]21C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])OC(=O)C1=C([H])C(O[H])=C(C(=O)C2=C(C([H])=C([H])C([H])=C2O[H])C(=O)OC([H])([H])[H])C(O[H])=C1[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C([H])=C1C([H])([H])[H])C1=NC([H])=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N2C([H])=C([H])C([H])=C2C1([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C([H])([H])C([H])([H])C#N)C([H])([H])C(=O)O1
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[N+]([O-])=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=C(N([H])C(=O)N([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NN=C(SC([H])([H])C(=O)N([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])S1
[H]N(C1=NC(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C2N=NN([H])C2=C1[H]
[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])N([H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(S1)C([H])([H])N1C([H])([H])C([H])([H])N([H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
CCCCCN1C=C[N+](CC(P(O)(O)=O)P(O)([O-])=O)=C1
[H]N(C(=O)C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C([H])S1)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=NN(C(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C(Cl)=C([H])C([H])=C2Cl)C([H])([H])[H]
[H]N([H])C1=C([H])C(=C(C(=N1)C([H])([H])[H])C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
CC1=CSC(NC(=O)C23CC4CC(CC(C4)C2)C3)=N1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(N1C([H])([H])[H])C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C(O[H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(N2[H])C2=C(C3=C(C([H])=C([H])N3C([H])([H])[H])C([H])=C2[H])C2=C1C(=O)N([H])C2=O
[H]OC1=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])C([H])(C(=N/OC([H])([H])C([H])([H])[H])\C4=C([H])C([H])=C(Br)C([H])=C4[H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=C([H])C([H])=N1)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C1=C(C2=NN=C(S2)C([H])([H])[H])C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=C(S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])[C@@]([H])(F)[C@]([H])(F)C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])C1([H])[H]
COC1=CC(\C=C\C2=NC3=C(O)C(=CC=C3C=C2)C(O)=O)=CC(=C1O)N(O)=O
CCCC(=O)NC1=CC=C(CC2=C(NN=C2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C(C)C)C=C1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C([H])=C(Cl)C([H])=C(Cl)C2=N1)C([H])([H])C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C21)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
CCCCCN1C=C(CC(=O)NC23CC4CC(CC(C4)C2)C3)C2=CC(Br)=CC=C12
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)O[C@]1(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@]2([H])[C@]3([H])C([H])([H])C([H])([H])C4=C([H])C(=O)C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]N([C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C3=C(OC([H])([H])C4([H])C([H])([H])C4([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C1[H]
[H]C1=C(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C2=C(O1)C1=C([H])C([H])=C([H])C([H])=C1C(=O)C2=O
[H]OC(=O)C([H])([H])[C@@]1(O[H])C2=C(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])=C(F)C(F)=C2[H]
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C2=C(C([H])=C1[H])N(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(C2=C(C([H])=C1[H])C(=NO2)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC([H])([H])C1=C2N(N=C([H])N=C2N([H])C2=C([H])C3=C(C([H])=C2[H])N(N=C3[H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])O\N=C1\C2=C([H])C([H])=C([H])C([H])=C2[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12OC([H])([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C2C([H])=C(C([H])=NC2=C1C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(OC1=C([H])C(=C(F)C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC2=C(Cl)C([H])=C(C([H])=C2Cl)N2N=C([H])C(=O)N([H])C2=O)C([H])=C1C(=O)N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]OC1=C(C(=O)N([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2N=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=NC2=C1C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])=C2[H])C1=C(F)C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)O[C@]1([H])[C@]([H])(C2=C(F)C(=C(F)C([H])=C2N([H])C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1N([H])C([H])=C2Cl)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])=NC2=C([H])N=C(C([H])=C2C1=O)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(\C([H])=C(/[H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC1=NC(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NC([H])=C1C([H])([H])C1=C([H])C(=O)N(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)N(C(=O)[C@@]1(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(F)C(Cl)=C1[H])C1=C([H])C([H])=C(N([H])C2=NC([H])=NC3=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C([H])=C1[H]
[H]N1C2=C([H])C(OC([H])([H])[H])=C(C([H])=C2C(=O)N(C([H])([H])[H])[C@]1(\C([H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])N=C([H])O1
[H]N(\N=C1\C2=C(N([H])C3=C2C([H])=C(F)C([H])=C3[H])C(=O)N([H])C([H])([H])C1([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]C1=C([H])C2=NC(=C([H])C([H])=C2C(=C1[H])C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C([H])C4=C(OC(=N4)C([H])([H])[H])C(Br)=C3C([H])([H])C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N([H])[C@@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])([H])OC(=O)C1=C(OC(=C(C(=O)OC([H])([H])[H])C1=O)C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C([H])C([H])=C(I)C([H])=C2O1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]\C(C1=C([H])C([H])=C([H])N=C1[H])=C1/C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)C([H])([H])C3=C([H])SC([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=N1)C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NC1=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
Cc1cccc(c1)[C@@H](CO)NC(=O)c1cc(c[nH]1)-c1nc(NC2CCOCC2)ncc1C
[H]C1=NC2=C([H])C([H])=C(Cl)C([H])=C2C(OC2=C([H])C([H])=C([H])C(Br)=C2[H])=N1
[H]N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=NOC(=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(C#N)=C1[H]
[H]C1=C([H])C([H])=C2N=C(OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])SC2=C1[H]
[H]O[C@]([H])(C(\[H])=C(/[H])[C@@]1([H])[C@]([H])(O[H])C([H])([H])[C@]([H])(O[H])[C@]1([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])[P@@](=O)(O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C1=C([H])C(F)=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N2C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C(N([H])C2=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C(N=C(C([H])=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=NC2=C1[H]
[H]OC1=C([H])C(F)=C([H])C([H])=C1C1=NC(N([H])C(=O)C2=C([H])C([H])=C([H])O2)=C(C#N)C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N([H])[H]
[H]OC(=O)C1=C(C(=NN1[H])C1=C([H])C(=C(O[H])C([H])=C1O[H])C([H])([H])C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C(=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(OC2=C(N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C(C([H])=C2[H])C(=O)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=N2)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(\C([H])=C2\C3=NC4=C([H])C(Cl)=C([H])C([H])=C4C(=O)N3C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C2([H])C([H])([H])C2([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])N1N=C(C2=C1C([H])([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C2(C1([H])[H])C([H])([H])C([H])([H])N(C(=O)C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])C1=NN([H])C(=O)C(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N1N=C(N=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C2C([H])=C(C([H])=C([H])C2=NC(=C1[H])C([H])([H])[H])N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]SC1=NN=C(N1N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])C1=C([H])C(C#CC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(C#CC2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=O)[C@@](S1)(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C(OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]O\C(OC([H])([H])C([H])([H])[H])=C1\C(=NC(=C(C(=O)OC([H])([H])[H])[C@]1([H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])N1C([H])=NC([H])=C1[H])C([H])([H])[H]
[H]C1=NC2=C(C([H])=C(C([H])=C2[H])C2=C3N(N=C2C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])N1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C(C(C#CC2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])[H])=C(OC([H])([H])C([H])([H])[H])C([H])=C23)=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=NN([H])C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(F)C(Cl)=C2[H])C([H])=C1[H]
C[C@H]1CN(C[C@@H](C)N1CC1=CN2C=C(N=C(N3CCOCC3)C2=N1)C1=CN=C(N)N=C1)S(C)(=O)=O
FC(F)(F)C1=CC(=CC(=C1)C(C1=CC=NC=C1)C1=CC2=C3N(CCC3=C1)C(=O)CC2)C(F)(F)F
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])S1)C([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]C1=NC([H])=C(N(C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])F)=C2[H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=NC(C2=NN=C(O2)C([H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@]([H])(O[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(Cl)C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])N([H])C(=S)N([H])C([H])([H])[C@@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H]
CC(C)N1CCCN(CC1)C(=O)C1=CC=C2C(CN3CCOCC3)=CN(C)C2=C1
[H]N([H])C1=NC(N([H])[H])=C(C2=C([H])C(\N=N\N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(Cl)C([H])=C2[H])C(=N1)C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1N1C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])SC(=O)C1([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2SC([H])=C(C2=C1[H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C3N=C([H])C([H])=C([H])C3=C([H])C([H])=C2C2=C([H])C(=C([H])C([H])=C2S1(=O)=O)C(F)(F)F
[H]N([C@@]1([H])C([H])([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])C2=C([H])C(=NN2C([H])([H])C([H])([H])[H])C(F)(F)F)C1([H])[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=NOC3=C2C([H])=C([H])C2=C([H])C(O[H])=C([H])C([H])=C32)C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(Br)=C1OC(=O)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@@]([H])(C(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C2(C(=O)N([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]N1C([H])=C([H])C2=NC(=C([H])C2=C1N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC(=NO1)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@]1([H])N(C(=O)C([H])([H])[C@]([H])(SC(=O)C([H])([H])[H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C2C(=O)N(C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2=C([H])C([H])=C1[H]
[H]N1C(=O)[C@]([H])(N(C(=O)[C@@]1([H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(N=C1[H])C([H])([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=C(N=C1[C@@]1([H])N([H])C(C2=C(C3=C(N2[H])C([H])=C([H])C([H])=C3[H])C1([H])[H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])[C@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]([H])(C1([H])[H])C2([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2=O)C1=C([H])C(O[H])=C([H])C(O[H])=C1[H]
[H]OC(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C(O[H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C2=C(C(=NC(=N2)C([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C(=O)[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])[C@]12C([H])([H])C(=O)C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C(\[H])=C(\[H])C([H])=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=O)N(C3=C([H])C([H])=C(F)C([H])=C3[H])C(=NC2=C1[H])[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(N=C(N([H])C([H])([H])C([H])([H])N([H])[H])N2C([H])=NN=C12)N([H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])N2C(=C1[H])C(OC(=O)C([H])([H])[H])=C(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C21
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=NC(=C3[H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C21)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1SC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C1C([H])([H])C([H])([H])N(C2=C(C(=NC(=N2)C2([H])C([H])([H])C2([H])[H])N([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C#N
[H]OC(=O)C1=C(O[H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C([H])=O)C([H])([H])C(=O)O[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(Cl)C([H])=C1N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[P@@](=O)(O[H])C([H])([H])[C@]([H])(C(=O)N(N([H])[H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C2=C(S1)[C@]1(O[C@@]([H])(OC([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(SC3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C3=C(N=C([H])C([H])=C3N2C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C(N=C(SC([H])([H])C2=NC3=C(Cl)C([H])=C([H])C([H])=C3C3=C([H])C(=NN23)C([H])([H])[H])N1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]1([H])SC([H])([H])C([H])([H])N1C(=O)C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N2C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=C(N=C3[H])C3=C([H])N=C(OC([H])([H])[H])C([H])=C3[H])N(C2=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C([H])C2=C1C([H])=C([H])C(=C2[H])N(C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N([H])C(=[N+]([H])[H])C1=C([H])C2=C(N([H])C(=C2[H])C2=C([O-])C(=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=C(N=C(C(OC([H])([H])[H])=N1)C1=C(OC([H])([H])[H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C2=C(C([H])=C1[H])C(=O)N([H])C1=C(N=C([H])C([H])=C1[H])N2C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])[C@@]([H])([C@]1([H])N([H])C(=O)C1=C([H])SC3=C1C([H])=C(F)C([H])=C3[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C#N)C(Cl)=NC(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1C#N
[H]N([H])C([H])([H])[C@]([H])(C(=O)N(C([H])([H])C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(Cl)C([H])=C(C([H])=C1Cl)C([H])([H])[H]
[H]OC1=C(C([H])=C(OC2=NC(OC3=C([H])C([H])=C([H])C(=C3[H])C(=N[H])N([H])[H])=C(F)C(=C2F)C([H])([H])[H])C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(S1)C([H])([H])C([H])([H])C([H])([H])C1=NN([H])C([H])=C21)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=C(C3=C2N=C([H])N=C3N([H])C([H])([H])C(=O)N([H])C2([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C([H])=C2N1[H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C(=O)OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])N(C(=O)N2OC(=O)C(=C2C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=NC2=C(C([H])=NC(=N2)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC(=O)C1=C([H])C([H])=C(N([H])C2=NC([H])=C([H])C(=N2)N([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C([H])N(C2=C1C([H])=C(N([H])C(=O)[C@@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])([H])[H]
[H]OC1=C2C([H])=C([H])C([H])=C([H])C2=C2N([H])C(=C(C(=O)OC([H])([H])C([H])([H])[H])C2=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC([H])([H])C(N([H])C1=NC(Cl)=NC2=C1N=C([H])N2C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(OS(=O)(=O)C2=C([H])C([H])=C([H])C(Cl)=C2Cl)=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])C2=NC([H])=NC([H])=C2[H])C([H])=C1[H])C1=NC(=NS1)C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1F
[H]N(C(N([H])C1([H])C([H])([H])C1([H])[H])=[N+]([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([O-])=O)[N+]([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=N1)N=C(N(C2=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C(=C(F)C([H])=C1[H])C(F)(F)F)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1O[H])C1=C([H])C([H])=C(O1)C(\[H])=C1/SC(=O)N(C1=O)C([H])([H])C(=O)OC([H])([H])[H]
[H]O[C@@]1([H])\C(=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])[C@@]4([H])N(C(=O)C([H])=C([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=NN1C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])[C@@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C(\C([H])=C(/[H])I)=C1[H])C2([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(\C([H])=C(/[H])C2=C([H])C(=NC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])([H])C([H])([H])N(C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]2(C3=C(OC4=C(C([H])=C([H])C([H])=C4[H])C2([H])[H])C([H])=C([H])C([H])=C3[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C(C(=O)C2=C(O[H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2O1)C([H])([H])[H]
[H]N([C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C(Cl)C([H])=C2C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C2C([H])=C(C([H])=NC2=N1)C([H])([H])N([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[C@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]2(C3=C(C([H])=C([H])C([H])=C3[H])[S@@](=O)C2([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(\C([H])=C(/[H])C([H])([H])N([H])C2=C([H])C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C3([H])[H])C(=C2[H])C(F)(F)F)=C([H])C([H])=C1[H]
[H]OP(=O)(O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C(=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H]
[H]C1=C(Br)C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N3C(=O)C([H])([H])C4(C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3=O)C([H])([H])C2([H])[H])C(Br)=C1[H]
[H]N1\C(S\C(=C(\[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O)=N/C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]N1C(=O)C([H])=C(C2=C([H])C([H])=C(F)C(F)=C12)C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C([H])([H])[H]
[H]C1=C2C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]34C([H])([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@@]4([H])[C@]2([H])C1([H])[H]
[H]N(C1=NC(=NC2=C1C(=C([H])S2)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1N=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])[C@@]1([H])C([H])([H])[C@]([H])(O[C@@]([H])(O[C@]2([H])[C@@]([H])(C([H])([H])[H])[C@]([H])(O[C@]3([H])O[C@@]([H])(C([H])([H])[H])[C@]([H])(O[H])[C@@](OC([H])([H])[H])(C([H])([H])[H])C3([H])[H])[C@]([H])(C(=O)O[C@]([H])(C([H])([H])C([H])([H])[H])[C@](O[H])(C([H])([H])[H])[C@]([H])(O[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]2(O[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@]1([H])O[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C(C([H])=C1C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N([H])C1=C2C(=C([H])C([H])=C1F)C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C2C(=O)C(=C([H])OC2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2S[C@@]([H])(C([H])([H])[H])[C@]([H])(OC2=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1N=C(C([H])=C1C(=O)OC([H])([H])[H])C1=C([H])C(F)=C(Cl)C([H])=C1Cl
[H]N(\N=C1/C(=O)N([H])N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(N(C(=N1)N([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=O)C([H])([H])[C@@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)OC([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C(C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(N1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2(C(=O)C([H])([H])C([H])([H])C2=O)C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C(=O)N(C([H])=C2[H])C([H])([H])[H])[C@@]([H])(C(=O)N(C([H])([H])C2=C([H])C(=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C2([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)N(N=C(C#N)C1=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])[N+]([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])S(=O)(=O)C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C(Cl)=C(OC([H])([H])[H])C([H])=C2[H])C1=O
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=NC([H])=C(C(=N2)N([H])C2=C([H])C([H])=C3N([H])C([H])=NC3=C2[H])C(F)(F)F)C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@@]2([H])C([H])([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C1(O[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)[C@]([H])(N1N=C(C(=C([H])C1=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C(OC(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])=C2[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=NC([H])=C(N1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC1=C(C([H])=C([H])C2=C([H])C([H])=C([H])N=C12)C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C3=C([H])OC([H])=C3[H])C([H])([H])C([H])([H])[C@]2(C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@](SC2=NC3=C([H])C(Cl)=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]S[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C(=O)N(C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N(C(=N1)C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=C([H])N=C4C([H])=C([H])C([H])=C([H])C4=N3)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C(OC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]N1C2=NC([H])=C(C([H])=C2C([H])([H])C2=C(C(C#N)=C([H])C([H])=C2[H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@@]([H])(N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N(C1=NC([H])=C(Br)N=C1C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2N(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C1=C([H])C(=NC(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N([H])C(=O)[C@]([H])(N([H])C(=O)C1=NC(=C(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])N=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]C1=C2N=C(SC2=C([H])C(=N1)C1=C([H])N=C(F)C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N1C([H])([H])C2=C(SC([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N1C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])[C@@]([H])(SC([H])([H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])C2=NC3=C([H])C(Cl)=C([H])C([H])=C3C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C(=O)[C@]([H])(N([H])C(=O)[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])N2N1C(=O)C(C2=O)(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]C1=NC(C2=C([H])N=C(S2)C(=O)N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C2N1C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C21
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N=[N+]=[N-])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])N1C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2SC3=C(OC2=C1[H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NOC3=C([H])C(F)=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])N=C(N=C1[H])N([H])C1=NN=C(O1)C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N(C1=NC2=C(N=NN2C2=C1SC([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC([H])=C2[H])C(F)(F)F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C2=C(C([H])=C([H])C([H])=C2[H])C(=N[C@@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C2=C([H])C([H])=C(Cl)C([H])=C2N1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C2C(=NC([H])=N1)N([H])C(=O)\C2=C(\[H])C1=C(C([H])=C(N1[H])C(=O)N1C([H])([H])[C@@]([H])(N([H])[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC(=C([H])S1)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C(F)(F)F)C(F)(F)F
[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C(=O)C3([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])N2C([H])=C(N=C2C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(OC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C(=O)C([H])([H])C1([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(C(=O)C([H])([H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(\C([H])=C(/[H])I)C([H])=C1[H])C2([H])[H]
OB(O)C1=CC(=CC=C1)C(F)(F)F
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])[N+]([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])S(=O)(=O)C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C1[H])C(=O)OC([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(N([H])S(=O)(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H]
[H]OC(=O)C([H])([H])C1(C([H])([H])S[C@@]([H])(C2=C([H])C(\C([H])=C(/[H])C3=NC4=C(S3)C([H])=C([H])C([H])=C4[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([C@@]1([H])C(=O)N([H])[C@@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N1C(SC([H])([H])[H])=NC(=C1C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=C(N([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(=O)C1=O)C1=C([H])C([H])=NN1[H]
[H]OC(=O)[C@@]([H])(OC1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])[C@]1(N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])[C@]([H])(O[H])C([H])([H])[C@]4([H])C([H])([H])[C@@]([H])(OC([H])([H])C([H])([H])N(C5=C([H])C([H])=C(C([H])=C5[H])[C@]5([H])C6=C7C(=C([H])C(=O)C([H])([H])C7([H])[H])C([H])([H])C([H])([H])[C@@]6([H])[C@]6([H])C([H])([H])C([H])([H])[C@@](O[H])(C#C[H])[C@@]6(C([H])([H])[H])C5([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])[C@]([H])(O[H])[C@]12C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(C3=C([H])C([H])=C(O[H])C([H])=C3O[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])SC([H])([H])C3([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])O2
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C(\[H])=C(/[H])C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])S1
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C(F)=C1C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C#CC([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C(F)(F)F)C([H])([H])C1=NC2=C(N=C(N=C2N([H])[H])N([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2=C(C([H])=C(O[H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C#N)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])=NC3=C([H])N=C4N([H])C([H])=C([H])C4=C23)C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C2=C(C([H])=C3C([H])([H])C([H])([H])[C@@](O[H])(C([H])([H])C([H])([H])C4=C(C([H])=C(F)C([H])=C4[H])C(=O)N([H])[H])[C@@]13C([H])([H])[H])N(N=C2[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=C2C(ON=C2C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])=C2[H])=NC([H])=N1
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])N1C(=O)[C@@]([H])(N([H])C(=O)C2=C([H])C3=C(N2[H])C(Cl)=C(Cl)S3)C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC([H])([H])C(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])(C([H])([H])O[H])C([H])([H])O[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N1C(=O)C(=NC(Cl)=C1C1([H])C([H])([H])C1([H])[H])N([H])C([H])([H])C1=NC2=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N2[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C(N([H])C3=NC([H])([H])C([H])([H])C([H])([H])N3[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
N[C@@H](CCCNC(=N)NN(O)=O)C(=O)N[C@@H]1CN[C@H](C1)C(N)=O
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C1([H])[H]
[H]N(C1=NC([H])=C2N(C(=O)N(C2=N1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(C(=NC2=C1N=C([H])C([H])=C2[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N/C([H])([H])C([H])([H])C([H])([H])[H])\N([H])[H]
[H]OC1=C(Br)C([H])=C(\C([H])=C2/C(=O)N([H])C3=C([H])C([H])=C4SC(=NC4=C23)N([H])[H])C([H])=C1Br
CNC1=NC(C)=C(S1)C1=C(C=NC(NC2=CC=CC(=C2)N2CCCCC2)=N1)C#N
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=NN=C(N1C([H])([H])C([H])([H])C(F)(F)F)C([H])([H])N1C(=O)C([H])([H])OC2=C(Cl)C([H])=C(Cl)C([H])=C12
[H]N(C1=C([H])C([H])=C2C(=C1[H])N(C([H])=C2C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C2C3=C(O[H])C([H])=C(O[H])C4=C3C3=C5C2=C1C(=O)C1=C5C(=C(C([H])=C1O[H])C([H])([H])[H])C1=C(C([H])=C(O[H])C(C4=O)=C31)C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C(=NN=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N=C(N([H])[H])C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=NC2=C(N1[H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])C2=O)C([H])([H])C1([H])[H])[N+]([O-])=O
OC1=CC=CC(\C=C\C(=O)NC2=CC=C(Cl)C=C2)=C1
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C(N=C1[H])C1=C([H])OC([H])=C1[H])C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2F
[H]O[C@]1(OC(=O)C(=C1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)N(C(=O)C2=C1C([H])=NC([H])=C2[H])C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])N(C3=C2C([H])=C([H])C([H])=C3[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N([H])C1=NC(N([H])[H])=C2C(=N1)C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C2C([H])=C(SC2=NC([H])=N1)C1=C([H])C([H])=C(O1)C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C(Cl)=C1[H]
COC1=CC2=C(CN(C[C@]3(NC(=O)NC3=O)C#CC3=CC=C(C=C3)C(=NO)C3=CC=C(F)C=C3)C2=O)C=C1
[H]N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])=NC([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@](C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])(C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C(N(C(=O)C([H])([H])[H])C([H])([H])[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=NN(C2=C1[C@]1(O[C@@]([H])(OC([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])OC(=O)C([H])([H])C1=C(Cl)C(Cl)=C([H])C([H])=C1Cl
[H]N1C2=C(C([H])=C(C([H])=C2[H])C(=O)C([H])([H])[H])[C@]2([H])C([H])=C([H])C([H])([H])[C@]2([H])[C@]1([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1Br
[H]N([H])C(=NC(=O)C1=C(C([H])=C(O1)C1=C(Cl)C([H])=C([H])C(Cl)=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=NC3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])[C@@]1([H])C([H])([H])C2([H])N(C([H])([H])C3=C([H])C([H])=C([H])O3)[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C1=NN(C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C([H])=C([H])C([H])=C3F)S(=O)(=O)C([H])([H])[H])C([H])=C12
[H]N1C([H])=C2C3=C(N=C([H])N=C13)C1=C(N([H])[C@]2([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1N=NC(=N1)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
C[C@@H]1CCCC\C1=N\NC1=NC(=CS1)C1=CC=C(C=C1)N(O)=O
[H]N([H])C(=O)C1=C(N([H])[H])C(=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N1C([H])([H])C2=C(C3=C([H])C([H])=C(C([H])=C3N2C([H])([H])[H])N2C([H])=C([H])C(=C([H])C2=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[N-]S(=O)(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(C(=C1C(=O)C([H])([H])OC1=C(N=C(C([H])=C1[H])C([H])([H])[H])[N+]([O-])=O)C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])[H]
[H]N(C1=N[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]OC([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])([H])[C@@]3([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@@]23[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(N([H])C([H])([H])[H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N1N=NN=[N+]1C1(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C1=C([H])C2=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)C2=O
[H]N1C([H])([H])[C@]([H])(C2=C([H])N([H])C([H])=N2)[C@@]1([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C(C(=O)C(=O)C2=C1C([H])=C([H])C1=C2C([H])([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])[C@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])N(C([H])([H])[C@@]([H])(N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(S1)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
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[H]N(C([H])([H])C([H])([H])OC1=C2C([H])=C([H])N([H])C2=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])N([H])C3=C([H])C([H])=C(F)C([H])=C23)C([H])([H])C1([H])[H]
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[H]N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C2C([H])=NN(C2=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(C(=O)C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C2=C(S1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
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[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])F)C([H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]OC1=C(O[H])C(C2=C([H])C([H])=C(F)C([H])=C2[H])=C2C(=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C([H])C(N([H])C(=O)C4([H])C([H])([H])C4([H])[H])=C3[H])C([H])([H])[C@]12[H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]N(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])[C@@]1([H])C(=O)N(C2=C([H])C([H])=C([H])C(OC([H])([H])C(=O)N([H])S(=O)(=O)C3=C([H])C(Cl)=C(Cl)S3)=C12)C([H])([H])[H]
[H]ON([H])C(=O)[C@@]1([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])=C(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(N(C3=C([H])C(=C([H])N=C23)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(C(F)=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N([H])C1=NC(N(C(=N1)N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C2N=C(C([H])=C(N2N=C1N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]\C(=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(F)=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H])S(=O)(=O)C1=C([H])C2=C(OC(C(=O)N2[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
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[H]N(C(=O)C1=C([H])C([H])=C(N([H])C2=C([H])C([H])=NC([H])=N2)C([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1Cl)C(=O)N([H])\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C([H])([H])S2)C([H])([H])C#CC1=C([H])C2=C(C([H])=C1[H])N1C(=NN=C1C([H])([H])N=C2C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H]
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[H]C1=C([H])C(C2=NN(C3=C2N=C(C([H])=C3N(C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])[C@]1([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(I)=C(C([H])=C1OC([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])[C@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])[C@](C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1C([H])([H])[H])C1=C(C#N)C([H])=NC2=C([H])C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C([H])=C12
[H]S\C(=N/C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H])N([H])C([H])([H])C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C(Br)=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N(C(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC(=NC(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C([H])N=C12)N([H])[H]
[H]C1=C([H])C([H])=C(O1)C1=C([H])N=C(OC([H])([H])C([H])([H])OC2=NC([H])=NC([N-]S(=O)(=O)C3=C([H])C([H])=C(C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])N=C1[H]
[H]N(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(N([H])N=C2[H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])[C@]([H])(C1=C(N([H])C2=C1C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F)C([H])([H])C2([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(N=NC(=C1[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1Cl)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])N(C#N)C1([H])[H]
[H]C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N1C([H])=NC([H])=C1[H]
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[H]N([H])C1=C([H])C([H])=C2C(=O)N(C(=O)C2=C1[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])OC2=C([H])C([H])=C(O[H])C([H])=C2C(=O)[C@@]1([H])C([H])([H])[H]
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[H]C1=NC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2N1C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]C1=C(F)C([H])=C(F)C(SC2=C(Cl)N3C(=NN=C3C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2Cl)=C1[H]
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ClC1=CC=C2C(=O)OC(=O)C3=C2C1=CC=C3
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[H]N([H])C1=C(C([H])=C(N(C1=O)C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C(=O)N([H])C([H])([H])[H])C([H])([H])[H])C(F)(F)F
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[H]C1=C([H])C([H])=C2C(=C1[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
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S=C1OC(=NN1CNC1=NC=CC=C1)C1=NC2=CC=CC=C2C=C1
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[H]OC(=O)C1=C([H])C([H])=C(N([H])C2=NC(N([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C(F)C([H])=N2)C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])OC1=C(C([H])=C(C([H])=C1C([H])([H])[H])C(=O)N([H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C(OC([H])([H])C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(N=C(C1=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1F
FC1=CC=CC2=C1N(CCCN1CCC(CC1)NC(=O)CC1=CC=CC=C1)C(=O)CC2
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[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])C([H])([H])C([H])([H])O[C@@]1([H])O[C@@]([H])(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C1=NC2=C(S1)C(=NC([H])=N2)N([H])C1=C([H])C(Cl)=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(OC([H])([H])[H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])C1=NN=C(N1C([H])([H])[H])[C@]12C([H])([H])C([H])([H])[C@](C3=NC(=NO3)C3=C([H])C([H])=C(F)C([H])=C3[H])(C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C2N([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C(N2N=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])N(N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=N1
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1SC([H])([H])C1=C2S[C@]([H])(C([H])([H])[H])C([H])([H])C3=C2C(=C([H])C([H])=C3OC([H])([H])C2=NC([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]ON([H])C(=O)N([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)[C@@]2([H])N([H])C(=O)N([H])C(=O)C2([H])[H])C([H])=C1[H])C([H])([H])O[H]
[H]N1C(=O)C([H])([H])C2=C([H])C(=C(F)C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C#N
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(F)=C([H])C(F)=C1[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C#N
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])[C@]2([H])C3=C(C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]O[C@@]1([H])C([H])=C([H])[C@@]23C4=C(C([H])=C([H])C(OC([H])([H])[H])=C4O[C@@]2([H])C1([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C3([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])S1)C1=NC(=O)[C@]([H])(S1)C([H])([H])C(=O)N([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@]([H])(O[H])C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N([H])[C@]1([H])C(=O)N([H])C(=O)[C@@](OC2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C(F)=C3[H])C([H])=C2[H])(C1=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(\[H])=C(/[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2N=C(C3=C2C([H])([H])C([H])([H])N(C3([H])[H])S(=O)(=O)C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])[H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1F)C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
CCN(C)C(=O)C1=CN=C2N(CCCOC)C(NC(=O)C3=CC=CC(=C3)C#N)=NC2=C1
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CC1=C([C@H](N2N=C(C=C2N1)C(F)(F)F)C1=CC=C(Cl)C(Cl)=C1)C1=NC=NN1C1CCC1
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])[C@]2([H])N(C(=O)C3([H])C([H])([H])C3([H])[H])C(=O)[C@@]([H])(C([H])([H])[H])[C@@]12[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C([H])C(=N1)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])O1
[H]N(C(=O)C([H])([H])N1N=C([H])C(OC2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)=C1[H])C1=C([H])N(N=C1[H])C([H])([H])C([H])([H])[H]
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[H]OC1=C([H])C(C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C2C([H])=C(C([H])=C([H])C2=N1)[C@](N([H])[H])(C1=C([H])N=C([H])N1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(SC2=C([H])C([H])=C([H])C([H])=C2[H])C(F)=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N1C2=C([H])C([H])=C1\C(=C1/N([H])\C(\C([H])=C1[H])=C(/C1=N/C(/C([H])=C1[H])=C(\C1=N\C(\C([H])=C1[H])=C2\C1=C(F)C([H])=C(F)C([H])=C1[H])C1=C(F)C([H])=C(F)C([H])=C1[H])C1=C(F)C([H])=C(F)C([H])=C1[H])C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C([H])([H])C([H])([H])[H]
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[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F)[C@@]1([H])[C@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[H]
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[H]OP(=O)(O[H])C([H])(N([H])C1=NC([H])=C(Cl)C([H])=C1[H])P(=O)(O[H])O[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C(N=C1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C(F)(F)F
[H]OC1=C([H])C(=C([H])C2=C1C1=C(C([H])([H])C([H])([H])N(C([H])([H])C(=O)N([H])C([H])([H])[H])C1([H])[H])C(O2)(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
CC(=O)NCCC1=CC=C(Cl)C(CN(C2CC2)C(=O)[C@H]2CNCC[C@@H]2C2=CN=C(OCCOC3=C(Cl)C=C(C)C=C3Cl)C=C2)=C1
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[H]OC(C([H])([H])[H])(C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])=C([H])[H])C([H])=C1[H])C1([H])C([H])([H])C23C([H])=C([H])C1(OC([H])([H])[H])C1([H])OC4=C(OC([H])([H])[H])C([H])=C([H])C5=C4C21C([H])([H])C([H])([H])N(C([H])([H])[H])C3([H])C5([H])[H]
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[H]OC1=C2N([H])C(F)=C(C2=NC([H])=N1)[C@]1([H])N([H])[C@]([H])(C([H])([H])O[H])[C@]([H])(O[H])[C@@]1([H])O[H]
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[H]N(C1=C([H])C2=C(S1)C(=NC(=N2)N([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])[H]
[H]C([H])(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CCCN(CCN1CCN(CC1)C1=CC=C(C=C1)C1=CC=CC=C1)C1CCC2=C(O)C=CC=C2C1
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[H]N([H])[C@]([H])(C(=O)N1[C@@]2([H])C([H])([H])[C@@]2([H])C([H])([H])[C@@]1([H])C#N)C1(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H])C1=C([H])C([H])=C2N=C([H])SC2=C1[H]
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[H]N(C(=O)C1=C([H])OC2=C([H])C([H])=C([H])C([H])=C2C1=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]O\C(OC([H])([H])C([H])([H])[H])=C1/C(=O)[C@]2([H])C([H])([H])[N@](C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C(=C23)C([H])([H])C1([H])[H]
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[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])[C@@]([H])(OC([H])([H])[H])C(=O)OC([H])([H])C1=C([H])[C@@]2([H])[C@@]3([H])O[C@@]4(O[C@@]3(C(=C([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]2(O4)[C@]2([H])C([H])=C(C(=O)[C@@]2(O[H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])[C@]([H])(O[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@@]1(O[H])C([H])([H])[H])C([H])([H])OC(=S)N([H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=NC(OC([H])([H])C([H])([H])[H])=C1C#N)N([H])C(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
COC(=O)C1C2CCC(C[C@@H]1C1=CC=C(C=C1)[Sn](C)(C)C)N2C
[H]OC1=NSC(N([H])C2=C([H])C([H])=C([H])C(Br)=C2[H])=C1\C(=N\C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]OC(=O)C([H])([H])OC1=C(O[H])C([H])=C(C([H])=C1OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]C1=C([H])N=C(C([H])=N1)C1=NN=C(SC([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])N1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C(Cl)=C([H])C([H])=C1N([H])C(=O)N([H])C1=C(Br)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]1([H])C(=O)N(C([H])([H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(C3=C(N2[H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N2C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])N(N=N2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)C1=C([H])C([H])=C(C#CC([H])([H])OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(OC([H])([H])C([H])([H])F)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])[H])C(=O)C2([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(Br)N=C1OC([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])SSC([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C(=O)O[H]
CCN1C2=C(N(C)C(OCC3=CC=C(Cl)C=C3)=C2)C(=O)N(CC)C1=O
[H]O[C@@]1(C([H])([H])[C@@]2([H])N([C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C([H])C([H])=C(C([H])=C3Cl)C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(F)C([H])=C1F)C1=C([H])C(C2=C(Br)C([H])=NN2C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]13C([H])([H])N(C([H])([H])C4([H])C([H])([H])C4([H])[H])C([H])([H])C([H])([H])[C@@]21C([H])([H])C([H])=C(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C3([H])[H]
[H]N(C1=C(C([H])=NC(=N1)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])S1)C1=NN([H])N=N1)C1=C([H])C([H])=C([H])C(=C1[H])N(C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(OC([H])([H])[C@]2(OC3=C([H])C([H])=C(C([H])=C3N(C([H])([H])[H])C2([H])[H])N(C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]C#CC([H])([H])N1C([H])=NC2=C1C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)N2C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[C@@]2([H])C1=O
[H]N(C1=NC([H])=C2ON=C(C2=C1[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])OC1=C([H])N2C(C([H])=C1[H])=C(C(=C2C(=O)C(=O)N([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
ON(=O)C1=CC(NC2=C3N=CNC3=NC(=N2)N2CCNCC2)=CC=C1
[H]C1=C([H])C(=C([H])O1)C1=NC(=NC(=C1[H])C1=C([H])OC([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[C@]([H])(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C1=NC([H])=N[C@]2([H])N(C([H])=N[C@]12[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N2N=C(N=C2[C@@]1([H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])ON=C3C4=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C4OC([H])([H])[C@]23[H])C([H])([H])C1([H])[H]
[H]OC(=O)C(\[H])=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C(/[H])C(=O)O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(OC2([H])[H])[C@]([H])([C@]1([H])OC([H])([H])[H])[C@]1(O[C@@]1([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1N=C(C(=C1[H])C1=C([H])C(=NC([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
COC[C@H]1O[C@@H](OCC2=CC=C3C=CC=CC3=C2)[C@H](NC(=O)CCCN)[C@@H](OCC2=CC=C(Cl)C=C2)[C@@H]1O
[H]O[C@]1(OC([H])([H])C(N([H])[C@@]1([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1F
[H]C1=C(C([H])=C(N1C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N(C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OP(=O)(O[H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]1([H])C(=O)N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(S1)C([H])=C(C([H])=C2[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C([H])([H])N1[C@@]2([H])C([H])([H])[C@@]3([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C2([H])[H])C3([H])[H]
[H]C1=C(N2N=C(C(N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C2S1)C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]N1C(=NC2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)C(F)(F)F)C1=C([H])N(C(=O)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1(O[C@@]([H])(C([H])([H])[S@@+]1[O-])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[N+]1(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1=NC(=C([H])N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2[H])N2C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]OC([H])([H])[C@@]([H])(F)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(C2=C([H])C([H])=NN2C([H])([H])[H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=NSC(N([H])C2=C([H])C([H])=C(OC3=C([H])C(Cl)=C([H])C([H])=C3Cl)C([H])=C2[H])=C1\C(=N\C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])N([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]\C(=C(\[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])[C@]1([H])N(C(=O)C([H])([H])C([H])([H])[H])[C@@]2([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C2=C(C([H])=C(F)C([H])=C2[H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]12[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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CC(C)C1=NOC(=N1)N1CCC(CO[C@H]2CC[C@@H](CC2)C2=CC=C(C=C2F)S(C)(=O)=O)CC1
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[H]N(C(=O)C([H])([H])C1=C([H])C(Br)=C([H])C(Br)=C1[H])C([H])([H])[C@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2S1)N([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C2N=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C(F)(F)F)C([H])([H])[H]
[H]O[C@]1(N2C(=NC([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(\C([H])=C2/SC(=O)N([H])C2=O)C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=C1[H]
CC(NC(=O)C1(N)CCN(CC1)C1=NC=NC2=C1C=CN2)C1=CC=CN=C1
[H]O[C@](C1=C([H])C([H])=C2N(N=C([H])C2=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])(C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C([H])=C([H])C(=N1)C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=N1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H][C@@]1(C[C@H](N)[C@H](O)[C@H](C)O1)O[C@H]1C[C@@](O)(CC2=C(O)C3=C(C(O)=C12)C(=O)C1=C(OC)C=CC=C1C3=O)C(\C)=N\OCC(=O)NCCCC[C@H](NC(=O)[C@H](CC1=CNC2=C1C=CC=C2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC1=CN=CN1)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CNC2=C1C=CC=C2)NC(=O)[C@H](CC1=CN=CN1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N(C([H])=C2[H])C2=C([H])C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)\C(=C(/[H])C2=C([H])C([H])=C([H])N2C([H])([H])[H])C(=O)N(C1=S)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=S)N([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])OC3=C([H])C([H])=C([H])C([H])=C3OC2([H])[H])C([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])N([H])[C@]1(C2=C([H])C(=C([H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(N=C(N=C2[H])N([H])[H])C([H])([H])C1([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=N\OC([H])([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(\C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])\C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(N=C(N2C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=C(N=C3N(C(=O)C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=N1
[H]OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])SC1=NC(N([H])[H])=C2C(OC(=C2C([H])([H])[H])C([H])([H])[H])=N1
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])[C@]1([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[C@@]1([H])N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]ON(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])SC1=NC2=C([H])C([H])=C([H])C([H])=C2S1)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C#N)C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C(N2C([H])=NC([H])=C12)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C2=NON=C12)[N+]([O-])=O)C([H])([H])C([H])([H])C([H])([H])N1N=C(C(=O)N([H])C2([H])C([H])([H])[C@@]3([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])C3([H])[H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])C([H])([H])C2([H])[H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
COC1=CC=C(C=C1)C1=CSC(NN=C2CCCCCC2)=N1
[H]C#CC([H])([H])N1C([H])([H])C2=C(N([H])[H])C3=C([H])C(C#N)=C(N=C3N=C2C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
COC1=C(C=CC(NC(=O)C=C)=C1)S(=O)(=O)N1CCN(CC1)C(=O)OC(C)(C)C
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C2=C(C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(N([H])[H])=C(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C2=C(N([H])[H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])ON1C(=O)C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C(=O)OC([H])([H])[H])[C@]12[H]
[H]C1=C([H])C2=C(N(C(=O)C([H])([H])O2)C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N3N=C(C4=C3C([H])([H])C([H])([H])N(C4([H])[H])S(=O)(=O)C([H])([H])[H])C3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C1C1=C([H])C([H])=C(C(F)=C1C([H])([H])S2)C([H])([H])[H])C(F)(F)F
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
CC1=CC(=CC=C1)C1=CSC2=C1OC(=CC2=O)N1CCOCC1
[H]N(C1=NN=C(SC([H])([H])C2=C([H])C([H])=C(F)C(F)=C2[H])N1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC(=C(S1)C1=NC(=NO1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])N(C(=O)C2=C(N3N=C([H])C([H])=C([H])C3=C2[H])C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(Br)C([H])=C([H])O1)[C@@]1([H])[C@@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N([H])C1=C(C([H])=C([H])C2=C1C([H])=C([H])N=C2[H])C1=C([H])C(OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)=C([H])N=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C([H])C3=C2C(=C1[H])C1=C(C#N)C(=O)N=C31
[H]N(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C2C([H])=C(OC([H])([H])[H])C(C#CC3=NC(=C([H])C([H])=C3[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C2=NC([H])=C1C#N
[H]N(C(=O)[C@]1([H])N(C([H])([H])SC1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])[C@@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])([H])N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])N(C([H])=O)C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C1=C(C2=C([H])C(=C(O[H])C([H])=C2[H])C([H])([H])[H])[C@@]2([H])[S@](=O)[C@]1([H])[C@]([H])(C2([H])[H])S(=O)(=O)OC1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
COC1=C(C)C=NC=C1C1=CC2=C(C=C1F)N1C(C)=NN=C1CC2
[H]ON([H])C(=O)C([H])([H])[C@]1(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])C3=C4C([H])=C([H])C([H])=C([H])C4=NC(=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1O[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2S1)C1=NC(=C(S1)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C(C#N)=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])C(=O)C2=C(O1)C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2O[H]
[H]N(C(=S)N([H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@@](N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C2([H])[H])(C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)C(F)(F)F
[H]N(C([H])([H])C1=C([H])C([H])=C(O1)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])N1C(N([H])C([H])([H])C1([H])[H])=C(C#N)C#N
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C(SC2=C1C(=O)C(=C([H])N2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C([H])N2C(=C1[H])[C@]([H])(N(C(=O)C([H])([H])N(C(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C2C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1F
[H]OC(=O)C1=C(C(=NN1C([H])([H])C1([H])OC([H])([H])C([H])([H])O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1Cl
[H]N([H])C1=NC([H])=NC2=C1N=C(Br)N2C([H])([H])[H]
[H]N(C(=O)O[C@]1([H])C([H])([H])[N@@]2C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[C@]1(O[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])[C@]([H])(N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C([H])([H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])[C@@]1([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])=C(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C([H])C(=N1)C([H])([H])SC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)O[H]
[H]N(C1=NN=C(O1)C1=C(N=C([H])N1C([H])([H])[H])N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(OC(F)(F)Cl)C([H])=C1[H]
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2OC1=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C(=O)C(=O)C1=C2C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])N(C3=C(Cl)C([H])=C4N=C(SC([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])N([H])C4=C3[H])C([H])([H])[C@]1([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])SC([H])([H])[C@]([H])(N([H])C1=O)C(=O)O[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]N([H])C1=C([H])C(=NC(OC([H])([H])C([H])([H])[H])=C1C#N)N([H])C(=O)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1OC([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]O[C@@]1([H])C2=C(N([H])C([H])=NC1([H])[H])N(C([H])=N2)C([H])([H])C([H])([H])C1=C2C(=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2C(=C1[H])[C@]([H])(C([H])([H])[H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1Cl)C(=O)N([H])\N=C(/[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C(OC([H])([H])C(=O)N([H])[H])C([H])=C1[H]
[H]C1=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=N1)C([H])([H])N1C([H])([H])C2(C1([H])[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C([H])([H])N1C(=O)[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C3=C(S2)C([H])=NC([H])=C3[H])C([H])([H])C1([H])[H])C(=N[H])N([H])[H]
[H]N([H])C(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N(C([H])([H])C2=C([H])C(N([H])C3=C([H])C([H])=C([H])C([H])=C3Cl)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1C([H])=C([H])N2[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN=C([H])N1[H]
[H]C1=C(C(=O)O[C@@]([H])(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=C2N1C([H])([H])C([H])([H])N(C2=O)C([H])([H])C([H])(F)F)C([H])([H])[H]
[H]N1C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(C(C(=O)SC([H])([H])C([H])([H])OC([H])([H])[H])=C1C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C1=C2C(=NC3=C(C([H])=C(Cl)C([H])=C13)C([H])([H])[H])N([H])N=C2C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N(C(=O)C1=C([H])C2=C(N=C(O2)N(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CCCC1(CNS(=O)(=O)C(F)(F)F)CCN(CC1)S(=O)(=O)C1=CC2=CC=CC=C2N1S(=O)(=O)C1=NC=CC=C1
[H]OC(=O)C([H])([H])OC1=C2C(C(=O)C(=O)N([H])[H])=C(N(C2=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
CC1=CC(O)=CC=C1C1=CC=C(S1)C1=C(C)C=C(O)C=C1
[H]N([H])C1=C2C([H])=C([H])C(=C([H])C2=C([H])C([H])=N1)C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(S1)[C@]1([H])C2=C(C([H])=C([H])S2)[C@@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC([H])([H])[C@@]([H])(N1C([H])=C(C2=C(N=C([H])N=C12)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])[C@@]([H])(N(C2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])N=C(C([H])=C1[H])C(F)(F)F
[H]N1C([H])=C(N=C1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C2N(C([H])=C(C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C(=O)N([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(N1C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N1C(=O)C([H])([H])C3(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1=O)C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C(N3N=C(C(=C3N=C2C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])SN=N2)C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C1=NN(C(=O)N1C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
O=C(NC1=CC=CC(=C1)C1=CN=CO1)N(CCC(C1=CC=CC=C1)C1=CC=CC=C1)CCN1CCOCC1
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])[N+](=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])O[C@@]1([H])O[C@]([H])(C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C(Cl)C([H])=C(C([H])=C1Cl)C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])[C@]12[H]
[H]N(C1=NC([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])[C@@]([H])(OC([H])([H])[H])O[C@]21C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)[C@@]2([H])N(C(=O)C([H])([H])C3([H])C4=C(C([H])=C([H])C([H])=C4[H])C([H])=C([H])C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=NN1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])SC1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C([H])=C3C(=O)C([H])=C(OC3=C2C([H])([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=NC(OC2=C([H])C(Cl)=C(N([H])C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])=C1\C([H])=N\OC([H])([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC(=NO1)C([H])([H])Cl)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])N2N=C(N=C12)C1=C([H])C([H])=C([H])O1)C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C([H])C(N([H])C2=C([H])C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=O)=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C(OS(=O)(=O)C3=C([H])C(F)=C([H])C([H])=C3[H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C3=C(OC([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(OC(=O)C2=C([H])C([H])=C([H])N2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N(C([H])([H])C2=C([H])C3=C(N=C(N=C3O[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])O[H])C(F)=C1[H])C(=O)O[H]
[H]OC(=O)C([H])([H])N1C(=O)N(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C(=O)N([H])[C@]([H])(C(=O)C2=NC3=C(O2)C([H])=C([H])C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(C1=O)(C([H])([H])[H])C([H])([H])[H]
[H]OC(C#CC1=C2N=C(N(C2=C(OC2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])=N1)C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC2=C1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C2([H])[H])C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C(=NC2=C(N=C1C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C1=NC2=C(S1)C([H])=C([H])C(N([H])C(=O)C1=C(C([H])=C(Br)C([H])=C1[H])C([H])([H])[H])=C2[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
CC1=C(C=CC(NC(=O)C=C)=C1)S(=O)(=O)N1CCN(CC1)C(=O)OC(C)(C)C
[H]N(C1=NC(=C(S1)C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])C(=N1)C1=C(N=C(S1)C([H])([H])[H])C([H])([H])[H]
[H]C1=C(Br)C(=NN1C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C(=O)C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])C2=C(C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H]
[H]OC(=O)C([H])([H])[C@]1([H])C2=C(C3=C([H])C(F)=C([H])C(=C3N2[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
OC1=CC=C2N=C(C3=CSC=C3)C(CNCCC3=CC=C(Br)C=C3)=CC2=C1
NCC1=CC=C(C=C1)C(=O)NC(C1=CC=C(Cl)C=C1)C1=NC2=CC=C(C=C2C(=O)N1)C1=CNN=C1
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2C([H])=NN([H])C2=C1[H]
[H]N1C([H])([H])[C@]2([H])N(C3=NC(=C([H])C([H])=C3C2([H])[H])C([H])([H])OC([H])([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N1C(=O)N([H])[C@@]([H])(C(C(=O)OC([H])([H])C([H])([H])[H])=C1C([H])([H])OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N([H])[C@@]1([H])C([H])([H])N(C2=NC(=NC3=C2OC2=C([H])C([H])=C(Cl)C([H])=C32)N([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]\C(=C(\[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@@]2(C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C3N([H])C4=C(C([H])=C(Cl)C([H])=C4[H])C3=C1[H])C([H])([H])C2([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])O[H]
[H]N([H])C(=O)C1=C(N([H])[H])C(=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C(N([H])C(=O)C(=O)OC([H])([H])C([H])([H])[H])=C1O[H])[N+]([O-])=O
[H]C1=C(N(C(=C1[H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)N([H])\C(C1=O)=C1/C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C3=C(N=C(N3C([H])([H])[H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)C(=O)C(F)(F)F)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(OC2=C(C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
Cc1cnc(NCC(F)(F)F)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
[H]OC1=C(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])N(C1=O)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N(C1=C2C([H])=C(OC([H])([H])C([H])([H])[H])C(OC([H])([H])C([H])([H])[H])=C([H])C2=NC([H])=N1)C1=C([H])C(F)=C([H])C(=C1[H])C(F)(F)F
[H]OC(=O)[C@@](OC1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C(=NC(=N2)N([H])[H])N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C([H])=N3)C([H])([H])C2([H])[H])C([H])=C1[H]
FC1=CC=C(NCN2N=C(OC2=S)C2=NC3=CC=CC=C3C=C2)C=C1
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])=C1C(=O)C([H])([H])[H]
[H]N1C2=C(C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C4C([H])=C([H])C([H])=C([H])C4=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1=O
[H]OC(=O)C1=NC2=C([H])C(=C([H])C([H])=C2N1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C(C(=O)N1C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=NOC(=N1)C1=NN(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])O[C@]2(O[C@](C(=O)O[H])([C@]([H])(OC(=O)SC([H])(C([H])([H])[H])C([H])([H])[H])[C@@]2([H])O[H])[C@]1(O[H])C(=O)O[H])C([H])([H])C([H])([H])C(=C([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NN(C2=C1C(=O)N(C(OC([H])([H])C([H])([H])C([H])([H])[H])=N2)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=N1)C([H])([H])[C@]1([H])C([H])=C(C([H])([H])[C@@]2(N([H])[H])\C1=C(/[H])C(F)(F)F)C(F)(F)F
[H]C1=C([H])C(=C([H])O1)C(=O)N(C1=C([H])C([H])=NC([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=N1)[C@]([H])(C1=C([H])C([H])=C(OC([H])(F)F)C(OC([H])(F)F)=C1[H])C([H])([H])C1=C([H])C([H])=[N+]([O-])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]O\N=C1/C(=O)N(C2=C([H])C([H])=C([H])C(C#N)=C12)C([H])([H])C1=C2OC([H])([H])OC([H])([H])C2=C([H])C(F)=C1[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])OC([H])([H])C1=C(C([H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])[H])=C1[H]
FC(F)(F)C1=CC=CC(SC2=NN3C(C=C2)=NN=C3C2=CSC=N2)=C1
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[H]N1C(=O)C2=C([H])C([H])=C([H])N2C2=C1C([H])=C([H])C(=C2[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@](C([H])([H])[H])(C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C([H])([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])OC(=O)N1C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC2=C([H])C(Cl)=C([H])C([H])=C2C(O[H])=C1C1=C([H])C(OC2=C([H])SC([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(Br)=C2OC(=NC2=C1[H])C1=C([H])C(=C(O[H])C([H])=C1[H])C(F)(F)F
[H]C1=C(Br)C([H])=C(S1)C1=NC(=C([H])N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F
[H]N(C1=NC([H])=C(Cl)C(=N1)N([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=NN1[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N([H])C(=O)N([H])C1=C(C(=O)N([H])[H])C2=C(S1)C1=C([H])N(N=C1C([H])([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)C([H])([H])N1C(=O)[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C([H])N=C12)N([H])C([H])([H])C1=C([H])C(N([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C(Br)=C(OC2=C([H])C([H])=C(O[H])C(=C2[H])C(=O)N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(Br)=C1[H]
[H]C1=C([H])C([H])=C([H])C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C3=C4C(=C([H])C([H])=C([H])C4=C([H])C([H])=C3[H])S2(=O)=O)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(S1)[C@]([H])(OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)N2C([H])([H])[C@@]([H])(C([H])=C3C4=C([H])C([H])=C([H])C5=C4C(=C([H])N5[H])C([H])([H])[C@@]23[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
CN1C=CC2=C1C(OC1=CC=C(NC(=O)NC3=CC=CC=C3)C=C1)=NC=N2
[H]N1C([H])([H])[C@@]2([H])N(C3=C([H])C(=C([H])C([H])=C3[H])C(F)(F)F)C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C1=NC(=C(N1[H])C1=C([H])C([H])=NC(=N1)N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])[C@@]([H])(OC1=C(C#N)C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C2=C1C(=O)OC2([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C(Cl)=C(C#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(OC([H])([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CC1=CC=CC=C1)N(C)C(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1=CNC2=C1C=CC=C2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC1=CN=CN1)NC(=O)[C@H](CCSC)NC(=O)[C@@H](N)CC(O)=O)C(N)=O
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N1C2=C([H])C([H])=C(C([H])=C2C(=N[C@@]([H])(C1=O)C([H])([H])N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([C@]1([H])C2=C([H])C(=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H])N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC1=C2N([H])C(=O)C([H])=C([H])C2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC(=O)N([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=NN1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(F)C(Br)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(OC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])N=C(S1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=NN2C(=N1)C(=C(N=C2C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])N1[C@@]2([H])C([H])=C(C3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]C1=NC(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C1=NC2=C([H])C(OC([H])([H])[H])=C([H])C(=C2C(=O)O1)C([H])([H])C([H])([H])[H]
[H]N1[C@@]2([H])C([H])([H])[C@]1([H])C([H])([H])N(C1=C([H])N=C([H])C([H])=C1[H])C2([H])[H]
[H]C1=C([H])C([H])=C(OC([H])([H])C2=C(N(N=C2C2=NN=C(O2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C(=O)OC([H])([H])[H])C(=C1[H])C(=O)OC([H])([H])[H])S(=O)(=O)C1=C(C2=C(S1)C([H])=C([H])C(Cl)=C2[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])N(C(=S)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C2N(C3=C([H])C(Cl)=C([H])C(Cl)=C13)C([H])([H])[C@]([H])(N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=NC2=C(C([H])=C(Cl)C([H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])C1=C(O[H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1
[H]C1=C(N(C2=C1C([H])=NC(=N2)C#N)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])SC1=C([H])C([H])=NC([H])=C1[H]
[H]C1=NC2=C(C([H])=C1[H])C(=O)N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=N2)[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(C(F)=C1[H])C(F)(F)F)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C([H])C2=C1[C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C2([H])[H]
[H]N([H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C2C(=NC3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@@]1([H])[C@@]([H])(C2=NC(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2[C@]1([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NOC2=C1C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])C(=O)N1C([H])([H])C([H])([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])C1([H])[H]
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[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N(C2=C1C([H])=C1C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2OC([H])=C(C2=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H]
[H]OC(=O)[C@]([H])(C1=C([H])C(N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=NC([H])=C2Cl)C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C(C2=C([H])C(\N=N\N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])C([H])([H])OC(=O)C([H])([H])[H])=C(Cl)C([H])=C2[H])C(=N1)C([H])([H])C([H])([H])[H]
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[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])[H])C([H])([H])N([H])C2=C(OC([H])([H])[H])C([H])=C([H])C(=C2[H])C([H])([H])[H])=N1
[H]N1C2=C(C([H])=C([H])C([H])=N2)[C@]2(C1=O)C([H])([H])C1=C(C([H])=C3C([H])=C([H])C(=NC3=C1[H])C([H])([H])N1C(=O)N3C4=C1C([H])=C([H])C([H])=C4N([H])C(=O)C3([H])[H])C2([H])[H]
COC1=CC=CC=C1NC(=O)CC1=NN(C)C(=O)C2=CC=CC=C12
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=NO[N+]([O-])=C1C(=O)N([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])N=C([H])C(=N1)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C2([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C2C([H])=C(OC([H])([H])[H])C([H])=C([H])C2=NC([H])=C1C#N
[H]O[C@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2N(C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(N=C(N=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NN=C(SC([H])([H])C([H])([H])[H])S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(C([H])=C2[H])C(SC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]N(OC([H])([H])[H])C(=O)C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=NC(=C(C(=O)N2C([H])([H])[C@@]3([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]4(C5=C([H])C([H])=C([H])C([H])=C5[H])C([H])([H])N(C(=O)C5([H])C([H])([H])C([H])([H])C([H])([H])C5([H])[H])C([H])([H])C4([H])[H])C([H])([H])[C@@]3([H])C2([H])[H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C2N=C(SC2=C1OC([H])([H])[H])N([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C(Cl)=C(SC4=NC([H])=C([H])C([H])=N4)C([H])=C3[H])C2=C1[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1SC1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C1=NC(=NC2=C1C(=C(N2C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C(N=C2C([H])=C([H])C([H])=NN12)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1(N([H])C(=O)[C@@]([H])(S[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(N([H])[H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])N(C1=O)C([H])([H])[H])C(=O)N([H])C([H])([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C([H])=C2C(ON=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C(C([H])=C3OC([H])([H])[H])C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H]
[H]OC1=C(C(=C2N=C(SC2=C1C([H])([H])[H])N([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C([H])([H])[C@@]12C([H])([H])C([H])([H])[C@]3([H])[C@]([H])(C([H])([H])C([H])([H])[C@@]4([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[C@@]34C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]21OC([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)C(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SSC1=NC([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N([H])C1=NC2=C(C([H])=C(S2)C(=O)N([H])C([H])([H])C([H])([H])[H])C(=N1)C1=C([H])C(OC([H])([H])C([H])([H])N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(Cl)C([H])=C1Cl
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])[C@](C(=O)N([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2OC([H])([H])C([H])([H])C([H])=C([H])[H])C([H])([H])C2=NC([H])=C(S2)C2=C([H])C([H])=C([H])O2)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C([H])([H])OC([H])([H])C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]\C(=C1\C(=O)C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])=NC([H])=C3[H])=C(OC([H])([H])[H])C([H])=C2C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C(=O)C1=C2C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])[C@@]21[H]
[H]ON([H])C(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(OC#CC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC([H])([H])[H])C1=NC([H])=C(SC2=C([H])C(C(=O)N3C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])[H])S1
[H]N([H])C1=NC(N([H])C([H])([H])[C@]2([H])N(C([H])([H])C3=C([H])C(Cl)=NC([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N(C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C2=C([H])C(=O)C([H])([H])C([H])([H])[C@@]2(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)O[C@@](C1=O)(C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C2=NOC3=C2C([H])=C([H])C(OC([H])([H])[H])=C3[H])C2=C([H])C([H])=C(C([H])=C12)C(F)(F)F)C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N2C(=O)C3=C([H])C(OC4=C([H])C([H])=C([H])C([H])=C4[H])=C([H])C([H])=C3N([H])C(=O)C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N=C(S1)C1=NN(C([H])=C1[H])C1=C2C(=NC([H])=C1[H])N(C1=C([H])C([H])=C(C([H])=C1S(=O)(=O)C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C2([H])[H]
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[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N1C([H])=C([H])C2=C1C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C2=C([H])C(Br)=C([H])C([H])=C2OC2=C1C([H])=C(Br)C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])/C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C\2([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)C(=O)N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C([O-])=O)C([H])([H])C([H])([H])SC([H])([H])[H]
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[H]N(C1=C(C2=C(N([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C1=C(C#N)C([H])=NC2=C1C([H])=C(S2)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])=NC(=C1C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C(F)(F)F
[H]N(C(=O)C([H])([H])[H])[C@]([H])(C1=C(C([H])=C([H])C(Cl)=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C(N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O)C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)N(C(=O)OC1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(C1=C([H])OC([H])=C1[H])=C1\C([H])([H])N2C3([H])C([H])([H])C([H])([H])[C@]2([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@]1([H])C3([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=NC(=NC(=C1[H])C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C(=O)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(Cl)=C([H])N=C1N([H])C(=N[H])N([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C2N=C(N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(C1=O)C1=C(C([H])=C([H])C3=C1N(C([H])=C3[H])C([H])([H])[H])C1=C2C2=C(N1[H])C([H])=C([H])C(Br)=C2[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]O[C@]([H])(C(\[H])=C(/[H])C1=C(SC(=C1C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]N=C(N([H])[H])N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])N(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])[C@@]([H])(OC(=O)C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(SC([H])(C(=O)N([H])C([H])([H])C2([H])C([H])([H])C2([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C(Cl)N=C12)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(I)=C1[H]
[H]O[C@](C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C1([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])N([H])C([H])([H])C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1Cl
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)[C@]1(C([H])([H])C([H])([H])[C@@]([H])(N([H])[C@@]2([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]O[C@@]([H])(C(=O)N([H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(O[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]1([H])C3=C(C(\C([H])=N\OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]1([H])OC([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])OC1=C([H])C2=C(SC3=C(N2[H])C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2O[C@@]3([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3(C2=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])N(C2=C([H])C(=C(Cl)C([H])=C2[H])C(F)(F)F)S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=NN([H])C2=C([H])C(=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(O1)C([H])([H])N1C(SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])=NN=C1C1=C([H])C([H])=C([H])C([H])=N1
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
O=C(NC12CC3CC(CC(C3)C1)C2)C1=NN(CCN2CCOCC2)C2=C1C=CC=C2
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])O1)C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])SC1=NC2=C(Br)C(Br)=C(Br)C(Br)=C2N1[H]
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[H]C1=C([H])C(=C2C3=C1C(=O)C(=O)C3=C([H])C([H])=C2[N+]([O-])=O)[N+]([O-])=O
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])C([H])([H])C3=C12)C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C1=NC([H])=C(N=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])P(=O)(OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])C(=O)N([H])C1=C([H])C2=C(N=C([H])N(C2=O)C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C(F)=C1C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C(I)C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1C(=O)N([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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CS(=O)(=O)NC1=CC=C2N=C(CN3CCC(CC4=CC=C(I)C=C4)CC3)NC2=C1
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])[C@]2([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[N@+]2(C([H])([H])[H])C([H])([H])Cl
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=NC2=C([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])=C2N1[H]
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[H]OC([H])([H])C([H])([H])N1N=C(N([H])C([H])([H])C(=O)N([H])C2([H])C([H])([H])N(C2([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@@]([H])(C3=C([H])C4=C(OC([H])([H])O4)C([H])=C3[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C(=C2[H])C(F)(F)F
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N1C(=O)C2=C(N=C1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1S2
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[H]N([H])C(=O)C1=C([H])C(N([H])C([H])([H])C2=NC(=C(N2[H])C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])=C([H])C([H])=C1[H]
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[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]1(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C(C(Br)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])N([H])[H]
CNS(=O)(=O)CC1=CC2=C(C=C1)C=CC1=C(C=C(C=N1)C1=CN(C)N=C1)C2=O
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[H]N([H])C1=NC(=C(N=N1)C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C(C([H])=C1[H])C([H])([H])N1C(=O)C(=O)C2=C([H])C(OC(F)(F)F)=C([H])C([H])=C12)C([H])([H])[H]
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[H]N([H])C(=O)C1=C([H])C2=C(SC3=C2N([H])C(=O)N(C3=O)C([H])([H])C([H])([H])N2C([H])([H])[C@@]3([H])C4=C([H])C([H])=C([H])C(OC([H])([H])[H])=C4C([H])([H])C([H])([H])[C@@]3([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=NC([H])=N1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
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CNC1=NC(C)=C(S1)C1=NC(NC2=CC(=CC=C2)S(N)(=O)=O)=NC=C1C#N
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)[C@@]12C([H])=C([H])C(=O)[C@@]3(OC4=C(OC([H])([H])[H])C([H])=C([H])C5=C4[C@]13C([H])([H])C([H])([H])N(C([H])([H])C1([H])C([H])([H])C1([H])[H])[C@]2([H])C5([H])[H])C([H])([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=C(C([H])=C(Cl)C([H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN2C(=NN=C2C([H])([H])OC2=C([H])C([H])=NC3=C2C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=C([H])C2=NC(=NN12)C1=C([H])C([H])=C(Br)O1)C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
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[H]N(\N=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N(C1=NC2=C(N=C(N=C2[H])N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])N1C([H])([H])C([H])([H])[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(F)(C(=O)O[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(N([H])C2=C(N([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])C(=O)C2=O)C([H])=C([H])C([H])=C1C(=O)N([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)N(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(SC#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])[H])[C@@]1([H])C([H])([H])N(C2=NC([H])=NC3=C2OC2=C([H])C([H])=C(Cl)C([H])=C32)C([H])([H])C1([H])[H]
CCCC1=C(C(=O)OCC)C(C(=O)OCC)=C2N1N=C(C=C2C1CCCC1)N1CCOCC1
[H]O[C@]1([H])C2=C([H])C(OC([H])([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])=C([H])C([H])=C2C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C2N=C(N([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C3=C([H])N=C([H])N3C2=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)OC1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C2=C(N([H])C([H])=C2C([H])([H])C(=O)N([H])C2=NC([H])=C(C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])S(=O)(=O)N([H])[H])C([H])=C1[H]
C[C@H](C[Si](O)(O)[C@@H](CC1=CC=CC=C1)NC(=O)C1=CC=CC=C1)C(=O)N1CCC[C@H]1C(O)=O
[H]OC([H])([H])C([H])([H])N([H])C1=C2N=NN(C2=NC(=N1)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]O[C@]1(C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])C1=C([H])N(C2=C1C(F)=C([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(F)(F)C(F)(F)F
[H]N(C(=O)C([H])([H])S(=O)(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C(F)C(=C([H])C([H])=C1[H])C1=C([H])C([H])=NN1[H])C1=NOC(=C1[H])C([H])([H])[H]
[H]N(C(=O)C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])C2=C([H])C(N([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2S1
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(N=C2[H])N2C([H])([H])[C@]3([H])N(C(=O)OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@@]2([H])C3([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]C1=C([H])C([H])=C2C(=O)C([H])=C(OC2=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C(C2=C([H])C(\N=N\N(C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)C([H])([H])C([H])([H])OC(=O)C([H])([H])[H])=C(Cl)C([H])=C2[H])C(=N1)C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C2=C1OC(=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])[H]
[H]N(C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])O1)C(=O)C([H])([H])SC1=NN=NN1C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(N1C2=C([H])C([H])=C(Cl)C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C(Br)=C(C([H])=C1[H])N(C1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C(=C1[H])C1=NOC(=N1)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]\C(=C(\[H])[N+]([O-])=O)C1=C([H])C([H])=C([H])N1C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(C([H])=C2C([H])([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C(=O)N([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])[C@@]([H])([C@]1([H])N([H])C(=O)C1=C([H])SC3=C1C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=NSC(=C1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C(C([H])=C2C(O[C@]([H])(C([H])([H])C2=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OS(=O)(=O)O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])C([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(ON=C1C1=C([H])C([H])=C([H])C(OC([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])[S@@](=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C(S1)C1=NN(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]OC1=C2N([H])C(=NC2=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C1=C(Cl)C([H])=C(F)C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H])C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C(F)C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])[C@]([H])(C#N)C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC(=O)C1=C(OC(=N1)C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])[H])N([H])[H]
[H]OC1(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@]2(C#N)C3=C(SC([H])([H])C4=C2C([H])=C([H])C([H])=C4[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(OC(=N2)N2C([H])([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C([H])=C1C([H])([H])[H]
[H]C1=C(N(N=C1OC([H])([H])C([H])([H])N1C(=O)C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])[H]
[H]C1=C(C([H])=C(N1C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])[N+]([O-])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)N([H])S(=O)(=O)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1(C([H])([H])C2=C([H])C(=C(C([H])=C2[H])N2C(=O)C3=C(OC([H])([H])C([H])([H])[H])C4=C([H])C([H])=C([H])C([H])=C4C(OC([H])([H])C([H])([H])[H])=C3C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]1([H])OC2=C([H])C([H])=C(Cl)C(OC([H])([H])C3=C([H])C([H])=C(OC([H])([H])C4=NC5=C([H])C([H])=C([H])C([H])=C5C([H])=C4[H])C([H])=C3[H])=C2C(=O)C1([H])[H]
[H]C1=C(C([H])=C(SC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])S1)[C@]1(OC(OC1([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C(C(=C1[H])C1=NC(=C2N=NC3=C(OC([H])([H])[H])C([H])=C(OC([H])(F)F)C([H])=C3N12)C([H])([H])[H])C([H])([H])[H]
CN1C(N)=NC2(CC(C)(C)OC3=C2C=C(C=C3)C2=CC=CN=C2)C1=O
[H]N(C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C2=C(N([H])C(=O)\C2=C(\[H])C2=C([H])N(C3=C2C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[H])C([H])=C1[H]
[H]N1C(=C([H])[C@@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C1C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C#CC([H])([H])OC([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]N1[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])[C@]([H])(C(=O)OC([H])([H])C([H])([H])F)[C@@]([H])(C1=C([H])C([H])=C(\C([H])=C(\[H])I)C([H])=C1[H])C2([H])[H]
[H]O[C@]1(C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])P(=O)(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(N=C3C([H])=C(C([H])=C([H])N23)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]O[C@]1([H])C2=C(C([H])=C([H])C(Cl)=C2[H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C2=C(N1[H])C(Cl)=C(Cl)S2
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C([H])C(=C1N(C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC(=O)C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)\C(=C(/[H])C1=C([H])C([H])=C([H])O1)C([H])([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=NC(=NN1[H])C(\[H])=C(/[H])C1=C([H])C(=C(O[H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1[C@]2([H])C3=C(N(C4=C([H])C([H])=C(C([H])=C34)S(=O)(=O)C3=C([H])C(F)=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]OC([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(OC(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N(C#N)C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([C@@]1([H])C([H])([H])N2C(=O)N(C3=C([H])C([H])=C(OC(F)(F)F)C([H])=C3[H])C([H])([H])[C@]2([H])C1([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])C(=O)N2C3=C(OC4=C2C([H])=C([H])C([H])=C4[H])C([H])=C([H])C([H])=C13)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[H]
[H]C1=C(N(N=C1C([H])([H])[H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C2=C(N=C([H])N(C2=O)C([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])SC([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(Br)C([H])=C([H])C([H])=C1[H])C1=NN([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C(F)C([H])=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[Cl-].NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CCC1=CC=CC(=C1)C(F)(F)F)B(O)O
[H]OC1=C(O[H])C(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])=C2C(=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C(N=NN1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2C(OC([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C(=O)C([H])([H])C4(C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3=O)C2([H])[H])=C1[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@]2([H])C([H])([H])N(C([H])([H])C3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C2=C([H])C3=C([H])C(=C([H])C([H])=C3N2[H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(N=C(N=C1[H])C([H])([H])[H])N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N1N=C([H])C(=C1[H])C1=C(SC2=C1N=C([H])N([H])C2=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
FC1=CC2=C(NC(=C2)C(=O)NCCN2CCC3(CC2)N(CNC3=O)C2=CC=C(Br)C=C2)C=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(SSC1=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N=C(SC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])N([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C(=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])[C@@]([H])(C([H])([H])[H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(N([H])P([O-])(=O)C([H])([H])N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)C([H])([H])N([H])S(=O)(=O)C([H])([H])[C@@]12C(=O)C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C2(O[H])O[H])C([H])([H])C(=O)O[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(=O)N(C1=C(C([H])=C([H])C([H])=C1[H])C(=O)O[H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(C(=O)N([H])C([H])([H])[H])C(O[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=O)[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N([H])C1=N[C@@](C2=C([H])C([H])=C([H])C(F)=C12)(C1=C([H])C(N([H])C(=O)C2=NC([H])=C(Cl)C([H])=C2[H])=C([H])C([H])=C1[H])C1=C([H])N(C(=O)C(=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NN([H])C2=C1C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C(=O)N([H])C1([H])C([H])([H])N(C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(F)=N1)C1=C([H])N=C2N=C(SC2=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C(O[H])C([H])=C2C([H])([H])[H])[C@]2([H])[S@@](=O)[C@@]1([H])C([H])([H])[C@]2([H])S(=O)(=O)OC1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1N1C(=O)C([H])([H])S[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(N=C(N2C([H])=C([H])N=C12)C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])[H])N([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(C2=C3N=C(C([H])=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1C([H])([H])[H]
[H]C1=C([H])C([H])=C(N2N=C3C(=C2C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C3=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]OP(=O)(O[H])OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N(C1=NC([H])=C([H])N1[H])C1=C([H])C2=C(N=C([H])C([H])=N2)C([H])=C1[H]
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[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])N(C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C2=NC([H])=C([H])C(=N2)N([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]N([H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN=C(O1)C(=O)N([H])C1=NN([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C(F)C(=N1)N([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1OC1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N([H])C1=NON=C1C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=NC(C#N)=C([H])N1[H])C1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C([H])=C(OC2=C(C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])[H])C(OC2=O)(C([H])([H])[H])C([H])([H])[H])C([H])=N1
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[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H]
CCCCN1C2=NC3=C(N2C=C1C1=CC=CC=C1Cl)C(=O)NC(=O)N3C
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[H]ON([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N([H])C(=O)C2=C([H])C3=C(O2)C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
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[H]OC1=C([H])C([H])=C2N=C3C4=C([H])C5=C(C(=O)N4C([H])([H])C3=C([H])C2=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC(=O)[C@]5(O[H])C([H])([H])C([H])([H])[H]
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[H]OC(=O)[C@@]([H])(OC1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])[C@]1(N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(=NN(C1=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(Cl)=C(SC([H])([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H][C@@]12CC[C@@]3(C)[C@@H](C[C@H](OCOCC[Si](C)(C)C)C(=O)[C@]3([H])[C@@]1(C)C[C@H](OC2=O)C1=COC=C1)C(=O)OC
[H]N(C(=O)C([H])([H])SC1=NN=C(N1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N1C([H])([H])[H])C1=C(F)C([H])=C(F)C([H])=C1[H]
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[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N1C([H])=C([H])N=C(N([H])C([H])([H])C2=C([H])C(=NO2)C([H])([H])[H])C1=O)C([H])([H])C([H])([H])[H])C(=O)C([H])([H])SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])C(C(=O)N([H])[C@@]([H])(C1=NN(N=N1)C([H])([H])[C@]([H])(C#N)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C2=C(C([H])=C1[N+]([O-])=O)C(=O)C(=O)C1=C2C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
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CC(OC1=CC=CC=C1)C(=O)NC1=CC=C2N=C(NC2=C1)C1=CC=NC=C1
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[H]OS(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)[C@]([H])(C([H])([H])S[H])C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]
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[H]OC1=C(O[H])C([H])=C(\C([H])=C(/C#N)C(=O)N2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
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[H]O[C@@](C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1([H])C([H])([H])C1([H])[H])(C([H])([H])[H])C(F)(F)F
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[H]O[C@]1(\C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])=C1\C(=O)N([H])C2=C([H])C([H])=C(C([H])=C12)S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])=C([H])[H]
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CCN(CC)C1=CC=C(CNC2=CC=C(Cl)C=C2)C=C1
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CC1=C(CCOCCO)C=C(N1C1=CC=CC=C1)C1=CC=C(C=C1)S(C)(=O)=O
[H]O[C@]([H])([C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])OC(=O)N(C([H])([H])C([H])([H])[H])C1([H])[H]
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[H]O[C@@]12N([H])C(=O)N([H])[C@]1([H])C([H])([H])S[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])\N=C1/C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(N([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])=C(F)C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C1=NC([H])=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1
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[H]N([H])C(=O)C1=C([H])C2=C(OC3=C([H])C([H])=C(C([H])=C3[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=NC([H])=C2S1
[H]O[C@]1([H])[C@@]([H])(C([H])([H])N([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N1C([H])([H])C2=C(N=C(N=C2C2=C([H])C([H])=C(F)C([H])=C2[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C3=NC([H])=NC(N([H])C4=NN([H])C(=C4[H])C([H])([H])C(=O)N([H])C4=C([H])C(F)=C([H])C([H])=C4[H])=C3C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=NC(=C(S1)C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=N1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(C(=O)N([H])C([H])([H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])S(=O)(=O)C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(F)=C([H])C(=C1[H])C1(C([H])([H])C([H])([H])N2C([H])([H])[C@]3([H])C([H])([H])N(C(=O)C4=C(C([H])=C(N=C4C([H])([H])[H])C#N)C([H])([H])[H])C([H])([H])[C@]3([H])C2([H])[H])C([H])([H])C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C(OC2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(OC([H])([H])C([H])([H])OC2=NC([H])=NC([H])=C2[H])=NC([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@](O[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(\[H])=C(/[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1N=NC2=C([H])C([H])=C(Br)C([H])=C2C1=O
[H]C([H])=C([H])C([H])([H])OC(=O)C1=C2C(=NC1=O)C1=C3C2=C([H])C([H])=C([H])C3=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(N([H])C(=O)N([H])[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2=C3C([H])=C([H])C([H])=C([H])C3=NC(=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC2=C(S1)C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C(\Cl)=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(N([H])C3=NN4C([H])=C([H])C([H])=C(C4=N3)C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C1=C(C([H])=C([H])[N+]([O-])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])N(C(=O)N([H])C1=C([H])C(Cl)=NC(Cl)=C1[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C([H])C(C#N)=C3[H])C([H])([H])[C@]2([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C1=NC([H])=NC2=C1SC1=C2C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)N2C([H])=NN=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(=O)C3=C([H])C([H])=C([H])C([H])=C3C(=O)C2=C(N([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])=C1S([O-])(=O)=O
[H]N(C1=NN2C(N=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])C2=C([H])C([H])=C(N([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
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[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])C(=O)C2(N([H])C(=O)C3=C([H])C4=C(C([H])=C3[H])C(=C(N4C([H])([H])[H])C3=C([H])N=C(OC([H])([H])[H])C([H])=C3[H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
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ONC(=O)C1=CCCCC1
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[H]N(C(=S)N([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]C([H])([H])N(C(=S)SSC(=S)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=NC(SC([H])([H])C([H])([H])C([H])([H])[H])=N1
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C(=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])[C@@]([H])(OC([H])([H])[H])C1=C([H])C([H])=C(F)C(=C1[H])C([H])([H])[H]
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[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]
[H]N(C1=NC(=NC2=C1C([H])=C([H])C([H])=C2[H])N(C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C(=C2[H])C2=C([H])C([H])=C(SC3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC(C#CC1=NC(OC([H])([H])[C@]([H])(N([H])[H])C([H])([H])[H])=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C(=C([H])C([H])=C1OC1=C(OC(=C([H])C1=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])[N+]([O-])=O
[H]N(C([H])([H])[H])C([H])([H])C1=NC2=C(SC3=C([H])C([H])=C(Cl)C([H])=C23)C(=O)N1[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C(=O)O[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(N([H])C(=O)OC2(C([H])([H])C2([H])[H])[C@]2([H])N(C([H])([H])S(=O)(=O)C3=C([H])C(F)=C(F)C([H])=C3[H])[C@@]([H])(C3=C([H])C([H])=C([H])C(F)=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C([H])C(=N1)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=NC(C([H])=C([H])[H])=C(C2=C([H])C([H])=C3N=C(N([H])C4=C(Cl)C([H])=C([H])C([H])=C4Cl)N(C3=C12)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2[H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C(=NC3=C2C([H])=C([H])N=C3[H])C([H])([H])[H])C2=C(OC(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2N1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C(=C2[H])C2=C([H])C([H])=C(SC3=C([H])C4=C(OC([H])([H])C([H])([H])O4)C([H])=C3[H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C2=NN=NN2C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C2=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1C2=O
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@@]1([H])SC2=C([H])C(O[H])=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C(OC([H])([H])[H])N=C(C(=N1)C([H])([H])[H])C1=C(Cl)C([H])=C(OC([H])(F)F)C([H])=C1[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]\C(=C(\I)C(F)(F)F)C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])[C@@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C2([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[C@]1([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1F)N1C([H])=C([H])C([H])=C([H])C1=O)S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C2=NN=C(C3=C([H])C([H])=C(C([H])=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C3=C([H])C([H])=C([H])C([H])=C23)[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])[C@]1([H])C2=C(OC([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C([H])C(=C23)C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])S1)C1=NC(=C(S1)C(=O)N([H])C1=C(Cl)C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=C([H])N2C1=NC([H])=C2C1=C([H])N([H])N=C1[H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(N([H])\N=C(/[H])C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N1C(=NC2=C1C([H])=C(Cl)C(Cl)=C2[H])N1C([H])([H])C([H])([H])C2(OC(=O)C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C1([H])[H])C([H])([H])[H]
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[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(SC2=C([H])C([H])=C(Cl)C([H])=C2[H])=NN(C1=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)\N=C(/N([H])C([H])([H])C(=O)N([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
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[H]OC(=O)C1=C(N([H])C2=C([H])C([H])=C(I)C([H])=C2F)C(F)=C(F)C(\C([H])=N\N([H])C(=O)C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])[H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N([H])[C@@]([H])(C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])[C@@]1([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=NC(=C(S3)C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(O[C@@]2([H])C([H])([H])[C@@]([H])(OC3=C([H])C([H])=C(N([H])C(=N[H])N([H])[H])C([H])=C3[H])[C@]([H])(N([H])C(=N[H])N([H])[H])C([H])([H])[C@]2([H])N([H])C(=N[H])N([H])[H])C([H])=C1[H]
[H]C1=C([H])C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C2C([H])=C(C(=NC2=C1Cl)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C([H])C([H])=C(Br)C2=C1[H])N1C(=O)[C@@]2([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])[C@@]2([H])C1=O
[H]C1=C2C([H])([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])C(=O)[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])C1=O
[H][C@@]12C[C@H](OC(=O)C3=CC=CC(=C3)C#N)[C@@]3(C)OC4=C([C@H](O)[C@]3([H])[C@@]1(C)CC[C@H](OC(C)=O)[C@@]2(C)COC(C)=O)C(=O)OC(=C4)C1=CN=CC=C1
[H]C1=C2C(ON=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])SC3=C([H])C([H])=C(C([H])=C3OC([H])([H])[H])C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C(F)=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C([H])C1=O)C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C(C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)O[H])C([H])([H])C(=O)O[H]
[H]ON(C([H])=O)[C@@]([H])(C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=C([H])C(=N1)C([H])([H])[C@@]1([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])[H]