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[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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CC1CCC(CC1)Nc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
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[H]N([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N/C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]1=C(C([H])=C(\C([H])=C(/[H])C2=C([H])C3=C4N(C([H])([H])C([H])([H])C([H])([H])C4=C2[H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])[H])\N([H])[H]
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[H]C#CC([H])([H])N([H])C1=NC([H])=NC2=C1C1=C(S2)C(=O)N(C([H])=N1)C1=C([H])C([H])=C(Br)C([H])=C1[H]
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[H]N([H])C1=C(C#N)C(=NC2=C1C([H])=C(C([H])=C2[H])C([H])([H])[H])C(F)(F)F
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[H]O\C(OC([H])([H])[H])=C1\C(=NC(=C(C(=O)OC([H])([H])[H])[C@@]1([H])C1=C([H])C(N([H])C(=N\C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])\N([H])C#N)=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
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[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(Cl)=NC2=C([H])C([H])=NN12
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[H]C1=C([H])N2C(=O)N(N=C2C([H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(\[H])C1=C([H])N(N=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=NC2=C1N([H])C([H])=C2[H])C1=C([H])C(=C(OC2=C([H])N=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)C(=O)N(C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2N=NN=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]OC([H])([H])C(=O)C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C4=C3C([H])=C([H])S4)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(N([H])C(=O)C([H])([H])SC1=NN=C(N1N([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])Cl)C(=O)C([H])([H])Cl
[H]O[C@]1([H])C([H])([H])C([H])([H])N2\C(=N\C3=C(C(Cl)=C(C#N)C([H])=C3[H])C([H])([H])[H])N(C(=O)N([H])[H])C([H])([H])[C@]12[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)C1([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C(=O)C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCCN)C(N)=O
[H]C1=C([H])C(=C([H])C([H])=C1F)N(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(SC#N)C(I)=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(N([H])[H])=C(C#CC([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])=N1
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC([H])=C([H])C(=N1)C1=NC([H])=C([H])S1
[H]C1=C(SC(=C1[H])[C@]1([H])OC2=C(N=NC(SC([H])([H])C([H])([H])[H])=N2)C2=C(C([H])=C([H])C([H])=C2[H])N1C(=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]2(OC([H])([H])[C@@]([H])(C3=C([H])C([H])=C(F)C([H])=C3[H])C(=O)C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(O1)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]C([H])=C(C1=C([H])C([H])=C2N=C(OC([H])([H])[H])C(=C([H])C2=C1[H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C2C([H])=C([H])N(C2=N1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
Cc1cnc(N)nc1-c1c[nH]c(c1)C(=O)NCc1ccccc1F
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[N+]1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[N+]1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C2C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])[C@@]21[H]
[H]O[C@@](C1=C([H])C(C#N)=C([H])C([H])=C1[H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C3=C(N=C([H])N3C([H])([H])[C@]12C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
COC1=CC2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=CC=C(C=C3)C3=NC(=CC=C3O)C3=CN(C)N=C3)C2=O)C=C1
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])S(=O)(=O)C(F)(F)F
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=NC([H])=C([H])C([H])=C2C1=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C([H])C(=O)N([H])C(=O)N2C([H])([H])C2=C(Br)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C(N([H])C(=O)OC([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=NC([H])=C4[H])C([H])([H])C3([H])[H])N=C([H])N=C2N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])S[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N1C([H])([H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C(OC2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1(N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
OCC1=C(O)C=CC(OCC(O)CNC2CCN(CC2)C2=NC=NC3=C2C(=CS3)C2=CC=CC=C2)=C1
[H][C@@]1(CCCCN1CC=C)[C@H](C(=O)OC)C1=CC=CC=C1
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])N([H])C4=C([H])C(=O)C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1C(F)(F)F)C(F)(F)F
[H]C1=C([H])C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=NN1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(N(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C([H])SC(=N1)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N([H])C([H])([H])C([H])([H])[C@@]([H])(OC1=C(C#N)C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])(OC1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]1(F)[C@]2([H])C([H])([H])[C@@]([H])(OC([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])[C@@](N([H])[H])(C(=O)O[H])[C@]12[H]
[H]N(C(=O)C([H])([H])N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(N([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(/C1=C([H])N=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])N(N=C1[H])C([H])([H])C1=NOC(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])N1C(=O)N([H])N=C1C1=C([H])C(=NC([H])=C1[H])N([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)N1C(=NC(C2=NN=C(S2)C2(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC(=O)C([H])([H])N([H])C(=O)[C@]12C([H])([H])N(C(=O)C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])[C@@]1([H])[C@]1(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[C@@]2([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(=N1)N1C([H])=NC2=C1C([H])=C([H])C(Cl)=C2[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC1=NC2=C(C([H])=C3C(N([H])[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])[C@]3([H])C([H])([H])C([H])([H])[H])=C2[H])C(=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC(=C([H])C([H])=N1)C1=C([H])C2=C(N1[H])C([H])([H])C([H])([H])N([H])C2=O
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2C2=C1C([H])=C([H])S2)C1=NN=C([H])N1[H])C1=C(Cl)C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C([H])C(Cl)=C3Cl)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(S[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=S)N([H])\N=C(/C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[H])[C@]([H])(N2C([H])=NC3=C(N=C(N=C23)N([H])C([H])([H])C([H])([H])C2=C([H])N(C([H])=N2)C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])N1N=NN=C1C([H])([H])[H]
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[H]C1=NC(=C([H])C([H])=C1[H])C1=NC(=C(SC2=C([H])C([H])=C(Cl)C([H])=C2[H])N1C([H])([H])[H])C1=C([H])N=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C(\[H])=C1\C(=O)N([H])C2=C([H])C([H])=C([H])C(Cl)=C12
[H]N(C1=NC([H])=C([H])C(=C1[H])C1=NN([H])C(=O)N1C1=C([H])C2=C([H])C([H])=C(Br)C([H])=C2C([H])=C1[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1S(=O)(=O)N([H])[H])N1N=C(C([H])=C1C1=C([H])C([H])=C([H])C(Cl)=C1[H])C(F)(F)F
[H]N(C(=O)[C@]1(C2=C([H])C(=C([H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]1([H])O[C@]2(O[C@](C(=O)O[H])([C@]([H])(OC(=O)C([H])([H])C([H])([H])C(\[H])=C(/[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@@]2([H])O[H])[C@]1(O[H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(OC(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
CN1C=C(C=N1)C1=CC2=C(C=CC3=C(C=C(CS(=O)(=O)NCC4=CSN=C4)C=C3)C2=O)N=C1
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C(=O)N([H])C([H])([H])[H]
[H]N=C(N([H])C(=O)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]O[C@@]1([H])C([H])([H])C(=O)[C@@]([H])(\C([H])=C(C([H])([H])[H])\C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(OC([H])([H])[H])[C@@]2([H])O[C@@](O[H])(C(=O)C(=O)N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C(=O)O[C@]([H])(C(=C(/[H])[C@]3([H])C([H])([H])C([H])([H])[C@@]([H])(OC([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])[C@]([H])(OC([H])([H])[H])C3([H])[H])\C([H])([H])[H])[C@]1([H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]2([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])=C([H])C2=NC([H])=NC(N([H])C3=C([H])C([H])=C(OC4=C([H])C([H])=C([H])C5=C4C([H])([H])C(=O)N5[H])C(Cl)=C3[H])=C12
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1F)N(C([H])([H])C#C[H])C([H])([H])C1=C(C([H])=C2N=C(N=C(O[H])C2=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C1=NN([H])C(O[H])=N1
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C12)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1Cl
[H]N([H])C([H])([H])C([H])([H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(C1=NC(=C([H])S1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(F)=N1)C1=C([H])C(OC([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])=C([H])N=C1Cl
[H]C1=C([H])C(Cl)=C([H])C(C#CC([H])([H])OC2=NSN=C2[C@]23C([H])([H])[N@@]4C([H])([H])[C@@]2([H])[C@@]3([H])C4([H])[H])=C1[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]1([H])C2=C(C(Cl)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])C(=O)\C(=C(/[H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C2([H])[H]
C[C@@H](O)[C@@H](C)OC1=C(Br)C=NC(NC2=CC=C(C=C2)S(=O)(CCO)=NS(=O)(=O)CC[Si](C)(C)C)=N1
[H]O[C@@]1([H])[C@@]([H])(O[C@@]([H])(O[C@]2([H])[C@]([H])(C(=O)O[C@]([H])(C([H])([H])C([H])([H])[H])[C@](O[H])(C([H])([H])[H])[C@]([H])(O[H])[C@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])[C@](OC([H])([H])[H])(C([H])([H])[H])[C@]([H])(O[C@]3([H])O[C@]([H])(C([H])([H])[H])C([H])([H])[C@]4([H])N(\C(O[C@@]34[H])=N\C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]2([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1(OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1(C#CC2=C([H])C([H])=C(C([H])=C2C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC1=C(F)C2=C(C(F)=C1O[H])[C@]([H])(N([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])[C@]1([H])C2=C([H])C(OC(=O)N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]N([H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(OC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C(=NC([H])=C1C([H])([H])[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(N2C([H])=C([H])N=C2C([H])=C1[H])C([H])([H])[H]
[H]N(N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]N1C(=O)C([H])([H])C([H])([H])[C@@](C1=O)(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N=C1[H])N([H])C(=O)C1=C([H])C(=NN1C1=C(C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C(N([H])C2=C([H])C(=NC(=N2)N2C([H])=NC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2F)N2C([H])=C([H])C([H])=C([H])C2=O)C([H])([H])[C@]1([H])N([H])C(=O)C1=C([H])C([H])=C(Cl)S1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]1([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(C1=C([H])C(Cl)=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C(F)(F)F)C(F)(F)F
[H]N(C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C2C([H])=C([H])C([H])=C(OC([H])([H])[H])C2=NC([H])=C1C(=O)C([H])([H])C([H])([H])[H]
[H]C1=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C2C(OC2=C(F)C([H])=C(C([H])=C2[H])C2=C([H])N=C(N(C2=O)C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C([H])=C(F)C([H])=C2[H]
[H]N([H])C([H])([H])C([H])([H])N1N=NC(=N1)N(C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)[C@]1([H])C2=C([H])C(=C([H])C([H])=C2N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])[H])C1([H])[H])C(F)(F)F
[H]OC1=C(Br)C([H])=C(\C([H])=C(/[H])C(=O)C2=C([H])C([H])=C(OS(=O)(=O)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C(C([H])=C1C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N(C1=NN=C(O1)C1=C(N([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]N([H])C(=O)C1=C2N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C3=C(C4=C(N3C(C([H])=C1[H])=C2[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C4=O)C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C(N=C([H])C([H])=C1[H])N([H])C1=C([H])C(F)=C(OC2=C3C([H])=C([H])N([H])C3=NC([H])=C2[H])C([H])=C1[H]
[H]N([H])C([H])([H])C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C(F)C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C(N=NN2C2=C1SC([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N1C2=C([H])C(OC([H])([H])[H])=C(C([H])=C2C(=O)N(C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])N=C([H])O1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(=NN1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C(=O)N([H])C1=C([H])C2=C(N=C([H])N(C2=O)C([H])([H])C2=C([H])C([H])=C(Cl)C(=C2[H])C(F)(F)F)C([H])=C1[H]
[H]C1=C(C(=O)C2=C(I)C([H])=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C2=C1[C@]1([H])N(C2=O)C([H])([H])C([H])([H])C1([H])[H])C1=NN([H])C(=C1[H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2N=C(N([H])C2=C1[H])C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])=C1[H])C([H])([H])N1C(=NC2=C([H])C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C12)C([H])([H])C([H])([H])C(=O)N([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(Cl)C([H])=C(C([H])=C1Cl)C([H])([H])C([H])([H])[C@@]([H])(O[H])C1=C([H])C([H])=C([H])C(O[H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])S1
[H]OC1=C([H])C2=C(OC(=C([H])C2=O)C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C2=C3C(=NC4=C([H])C(Cl)=C([H])C([H])=C24)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H]
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[H]N(C(=O)C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C2C3=C4C(C([H])=C([H])C([H])=C4C(=O)C2=C1[H])=C([H])C([H])=N3
[H]O[C@@]1([H])C([H])([H])N(C(=O)C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C2[H])C1([H])[H]
[H]O[C@]1([H])C2=C([H])C([H])=C(C([H])=C2[C@@]([H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(C#N)N1C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(OC(F)(F)F)=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C1C(=C(O2)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]N([H])S(=O)(=O)C1=NN(\C(S1)=N/S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1(C(=O)N([C@@]([H])(C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[H]
[H]N(C1=N\C(=C(\[H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C(=O)N1C([H])([H])[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N1C([H])=C([H])N=C(N([H])C([H])([H])C2=NON=C2C([H])([H])[H])C1=O)C([H])([H])C([H])([H])[H])C(=O)C([H])([H])N([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=NC2=C1C([H])([H])[C@]([H])(C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N1N=C(C2=C1C(=C([H])C(=C2[H])C(=O)N1C([H])([H])C([H])([H])C2(OC3=C(N(N=C3C(=O)C2([H])[H])[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C([H])=N1)C1=C([H])C2=C(N1C([H])([H])C([H])([H])C([H])([H])C(F)(F)F)C([H])([H])C([H])([H])N([H])C2=O
[H]N(C1=C([H])C([H])=C([H])C(Br)=C1[H])C1=NC([H])=NC2=C1C([H])=C1N=C([H])N(C1=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C(=N1)C([H])([H])SC1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=NN=C(O1)SC([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])C(F)(F)F
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C(=NN1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]S\C(=N/C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])Br)=C([H])C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)N([H])C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C2=C(C([H])=C1[H])N(C([H])([H])[H])[C@]1([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])[N@@+]1([O-])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C(C#N)C([H])=NN2C([H])=C(C(=O)N([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(=C12)C([H])([H])[H]
[H]N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C(Cl)=C13)[C@]1([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(\C([H])=C2\C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@]3(C2=C(O[H])C(=O)C2=C3[C@]([H])(OC(=O)C([H])([H])[H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])[C@]23[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C(N=C1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=S)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C(OC([H])([H])[H])=C(C2=C1C(=O)OC2([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])N(N=N1)C([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C2=C1N=C(N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C([H])C([H])=NC([H])=C21
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OP(=O)(O[H])O[H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])N=C(N=C1C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]1([H])N2C(=NC3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C3OC([H])([H])C([H])([H])OC3=C2[H])C(O[C@]2([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]2([H])O[H])=C([H])C(Cl)=C1[H]
[H]OC1=C(Cl)C([H])=C2C(N([H])C(=NC([H])([H])C2([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
COCCCN1C(NC(=O)C2=CC(=CC=C2)C#N)=NC2=CC(=CC=C12)C(=O)NCC1=CC(OC)=CC=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C2=NN=C(C3=C([H])C([H])=C(C#N)C([H])=C3[H])C3=C2C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=C2N=C(OC2=C([H])C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C(Cl)=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C(=O)C([H])([H])C1([H])[H])C1=C([H])N=C([H])C([H])=N1
[H]OC(=O)C(=C(/[H])C1=C(C(=O)C(=C(C1=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])[H])\C([H])([H])[H]
[H]OC(=O)C(OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C1/C(=O)N([H])C2=C1C([H])=C(C#CC([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C(=O)[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
COC1=CC(=CC=C1OCCCNC(=O)NC1=CC=C(OC(F)(F)F)C=C1)C1=C(NC2CCCC2)N2C=C(C)C=CC2=N1
ON(=O)C1=CC2=C(C=C1)N=C(NCCC1=CC=C(NC3=NCCS3)C=C1)S2
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])N1C(=O)C(Cl)=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1=O
[H]C1=C([H])C(=O)N2C(=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])[C@@]([H])(C2([H])[H])C1([H])[H]
[H]N1C2=C(C(=O)C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(C(=O)N(C4=C([H])C([H])=C(Cl)C([H])=C4[H])C4([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C([H])([H])[C@@]3([H])[C@]2([H])C1([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1N(C(=O)N1C2=N[C@@]([H])(C([H])([H])C([H])([H])[H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)[C@@]([H])([N+]([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])[C@@]1(C#N)C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)N2C([H])([H])C([H])([H])C([H])(N3C(=O)N([H])C4=C3C([H])=C([H])C([H])=N4)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])=C(C2=C([H])C([H])=C(Br)C([H])=C2[H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
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[H]OC([H])([H])C1=NN(C(=C1C1=C([H])C([H])=C(C([H])=C1C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])[H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N(C([H])([H])C1=C(F)C(F)=C(F)C(F)=C1F)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]C1=C([H])C(=C([H])C(=C1Cl)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C1=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N1N=NN=C1C1=C([H])C([H])=C([H])C(=C1[H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=NC(C2=C3N=C(C([H])=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]C1=NN(C([H])=C1S(=O)(=O)N1C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=NC([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NSC(=N1)C1=C([H])C(O[H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])N1C(=O)N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]23C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2([H])[H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])[C@@]([H])(O[H])C([H])([H])N2[H])=C([H])C(N([H])[H])=C1[H])C1=C([H])C(Cl)=C([H])C(I)=C1O[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])N([H])[H]
[H]S\C(=N\C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H]
Cc1cccc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2cccc(F)c2)c1C
[H]OC1=C(N([H])C2=NSN=C2N([H])[C@@]([H])(C2=C([H])C([H])=C(S2)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(Br)=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C([H])C([H])=C([H])C(O[11C]([H])([H])[H])=C2C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C1=NC([H])=C(O1)C1=NC([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])C([H])=C1[H]
[H]N([H])C1=NN2C([H])=C([H])C([H])=NC2=C1C1=NC([H])=NC(=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(S1)C([H])([H])C([H])([H])C([H])([H])C1=NN([H])C([H])=C21)C1=NC(C#N)=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1(C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])C1=C([H])C(=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C#N)[C@@]1([H])C([H])([H])N(C(=O)O[C@@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])S1)C1=C(N=C2N=C([H])C([H])=C([H])N12)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CN(C(=O)CN1C(=O)OC2=CC=C(C=C12)C1=CC=CC=C1)C1=CC=NC=C1
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=NOC([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C(=O)N(C([H])([H])C1=NC([H])=C([H])S1)C([H])([H])C([H])([H])C([H])([H])[H])N([H])[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C([H])SC([H])=C1[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C(N=C2N1[C@]([H])(C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C2=C(N([H])[H])C([H])=C(N([H])[H])C([H])=C2C([H])=C1[H])C(=O)O[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])N1C(=O)S\C(=C(/[H])C2=C([H])OC3=C([H])C([H])=C(C([H])=C3C2=O)[N+]([O-])=O)C1=O
[H]C1=C([H])C(C2=NN(C3=C2N=C(C([H])=C3N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]2([H])OC([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]OC(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])=NC2=C1N([H])C([H])=NC([H])([H])[C@@]2([H])O[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])=C1[H])C(=O)N([H])C1=C([H])N(N=C1C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C(ON=C2C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C([H])([H])[H])C1=NN2C([H])=C(C([H])=C([H])C2=N1)C1=C(N=C(S1)C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C2OC([H])([H])C([H])([H])OC2=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C1=NC(=NS1)N1C([H])=NC([H])=C1[H])C([H])([H])[H]
COC1=CC2=C(CN(C[C@]3(NC(=O)NC3=O)C#CC3=CC4=C(C=C3)C(C)=NN4)C2=O)C=C1
[H]C1=C([H])C(=C([H])C(Cl)=C1[H])[C@@]([H])(N(C(=O)C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N1C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=NN([H])C2=C1C([H])=C(C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])S1(=O)=O
[H]N(C(=O)C([H])([H])[H])C1=C(N(C([H])([H])[H])C([H])([H])[H])C(=O)N(C2=C1C([H])=C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C1=NN=C2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C(C(=O)C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])N([H])C(=O)C([H])([H])SC1=NC2=C(C3=C(S2)C([H])([H])N([H])C([H])([H])C3([H])[H])C(=O)N1C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]O[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C(OC(F)(F)F)C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H])C([H])([H])C([H])([H])N1N=C([H])C(Br)=C1C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]S\C(=N/C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H])C([H])([H])OC(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2N2C(=O)C(C2=O)(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1[H]
[H]OC(=O)C(=C(/[H])C1=C(Br)C([H])=C([H])C(OC([H])([H])C2=C([H])SC([H])=C2[H])=C1[H])\C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(=C([H])C([H])=N1)N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=NC(=NN2C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=NN2C(=N1)C(O[H])=NC1=C([H])C(Cl)=C(Cl)C([H])=C21
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C(F)C([H])=C(O[H])C([H])=C2F)C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C2([H])C([H])([H])C2([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(Cl)N=C2N([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C([H])C(Br)=C(OC([H])([H])[H])C(Br)=C1[H])=C(O2)C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(N=C=S)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=NN1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)OC([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=O)OC([H])([H])[H])[C@]2([H])O[C@@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N1N=C(C2=C1C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@]([H])(N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C(=C([H])C([H])=C2[H])[N+]([O-])=O)C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C(N(\N=C(/[H])\C(\[H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C1=S)C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(N=N1)C([H])([H])C([H])([H])C#N
[H]N([H])C1=C(C(=O)OC([H])([H])C([H])([H])[H])C2=C(S1)C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])SC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])[C@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C2=C([H])C3=C(O[C@@]2([H])C1([H])[H])C([H])=C(OC3=O)C([H])([H])[H]
[H]OC([H])([H])[C@@](N([H])[H])(C([H])([H])OP(=O)(O[H])O[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(SC2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])=C1F
[H]N(C(=O)N([H])C([H])([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(C#N)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(Cl)=C3Cl)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C([H])C3=C(C([H])=C2S1)C([H])([H])[C@@]1([H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[C@@]32C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C(C#N)C(=N1)N([H])[H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])[C@@]([H])(OC(=O)C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])SC([H])([H])[C@]2([H])N([H])C(=O)N([H])[C@]12[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C1=C2N=C(N1C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])[H])C1([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(SC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C(=C1C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C(C2=C([H])C3=C(N2[H])C([H])=C([H])C(=C3[H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C([H])C([H])=C(C([H])=C12)C(=O)OC([H])([H])[H]
OC1=CC=CN(CC2=CC=C(C=C2)C2=CC=NC=C2)C1=S
[H]N(C(=O)O[C@]1([H])C(=O)N(C(=O)C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1O2)C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H]
[H]N(C1=NC([H])=C(C(=N1)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C2N([H])C([H])=NC2=C1[H]
[H]O[C@@]1(C(=O)OC([H])([H])C2=C1C([H])=C1N(C2=O)C([H])([H])C2=C([H])C3=C([H])C4=C(OC([H])([H])O4)C([H])=C3N=C12)C([H])([H])C([H])([H])[H]
CC(C)(C)OC(=O)N(CC1=CC=CC=C1)[C@@H]1CCN(C1)C(=O)OC1C2CC3CC(C2)CC1C3
[H]N(C(=O)N([H])S(=O)(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1([H])C([H])([H])C([H])(OC(=O)C([H])([H])[H])C(=O)C2([H])C1(C([H])([H])[H])C([H])([H])C(=O)C1([H])C([H])([H])OC([H])(C3=C([H])OC([H])=C3[H])C([H])([H])C21C([H])([H])[H]
[H]OC(=O)[C@@]1(F)[C@]2([H])C([H])([H])[C@@]([H])(OC([H])([H])C3=C([H])C(=C([H])C([H])=C3[H])C([H])([H])[H])[C@@](N([H])[H])(C(=O)O[H])[C@]12[H]
CC1(C)CCC2=C(N=C3SC4=C(NCC5=CC=NC=C5)N=CN=C4C3=C2C1)N1CCOCC1
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=C([H])C(=NC2=O)N([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C(=C(/[H])C1=C([H])N=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])\[C@@]([H])(C1=C([H])C([H])=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=C(/[H])C([H])([H])C1=C(O[H])C(=C(C(=C1OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])\C([H])([H])[H]
[H]OC(=O)C1(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])[C@]3([H])C([H])([H])C4=C(C5=C([H])C(=C([H])C([H])=C5N4[H])C(F)(F)F)[C@]([H])(C([H])([H])[H])[C@@]3([H])C2([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1(C2=NN(N=N2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
C(N1CCOCC1)C1=COC2=CC(OC3=NC4=CC=CC=C4S3)=CC=C12
[H]C1=NC([H])=C(C#CC2=NC(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])N(C(=O)C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C(C2=NC([H])=C([H])N2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2F)(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CCC(NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1)C(=O)C(=O)NCCCN1C=NC2=C1N=CN=C2N
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C([H])C([H])=C(C#CC3=C([H])C([H])=C([H])N=C3[H])C([H])=C12
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C1=C([H])C(=C([H])C([H])=N1)C1=C([H])C2=C(N1[H])[C@]1(C([H])([H])N([H])C2=O)C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(OC([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N1[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)C([H])([H])[C@]([H])(C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C(=O)[C@@]([H])(\C([H])=C(C([H])([H])[H])\C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(OC([H])([H])[H])[C@@]2([H])O[C@@](O[H])(C(=O)C(=O)N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C(=O)O[C@]([H])(C(=C(/[H])[C@]3([H])C([H])([H])C([H])([H])[C@@]([H])(OC([H])([H])C(=O)N([H])C4=C([H])C([H])=C(C([H])=C4[H])C([H])([H])[H])[C@]([H])(OC([H])([H])[H])C3([H])[H])\C([H])([H])[H])[C@]1([H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]2([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C2=NN(N=C2C(=NC2=C1C([H])=C([H])C(Cl)=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=NC(=NO2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])N=C([H])C(Br)=C1[H])C(=O)C([H])([H])SC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N(C1=NC([H])=C([H])C2=C1C1=C([H])C([H])=C([H])C([H])=C1N2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]2([H])OC(=O)[C@@]3([H])N(C(=O)C(=O)[C@]4(O[H])O[C@@]([H])(C([H])([H])C([H])([H])[C@@]4([H])C([H])([H])[H])C([H])([H])[C@@]([H])(C4=C([H])C([H])=C([H])O4)\C(=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C([H])\[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)[C@]([H])(OC([H])([H])[H])[C@]([H])(O[H])\C(=C([H])\[C@]([H])(C(=O)C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])[H]
[H]N1C(=C([H])C2=C([H])C(=C([H])C([H])=C12)C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N2C(=N1)C(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C21
[H]O[C@]([H])(N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C(Cl)C([H])=C([H])C(N([H])C([H])([H])C(F)(F)C2=NC([H])=C([H])C([H])=C2[H])=[N+]1[O-]
[H]N1C(=O)N([H])[C@]([H])(C([H])([H])C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C(=O)N(C([H])=C2[H])C([H])([H])[H])[C@@]([H])(C(=O)N(C([H])([H])C2=C([H])N(C3=C2C(F)=C([H])C([H])=C3[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C2([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C1=NC([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(OC(=O)N(C3=C([H])C([H])=C([H])C([H])=N3)C2([H])[H])C([H])([H])C1([H])[H]
COC1=C(OCCCNC2=CC=CC=C2)C2=C[N]3=C(C=C2C=C1)C1=CC2=C(OCO2)C=C1CC3
[H]N([H])C1=C(C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])=C2[H])C(=NC2=C([H])C([H])=NN12)C([H])([H])[H]
[H]N(C1=NC(=C(S1)C([H])([H])N(C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C(F)(F)F)C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C([H])=C(S1)C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[N@@+](C([H])([H])[H])(C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C1([H])[H]
[H]O[C@]([H])(C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])P(=O)(O[H])O[H]
[H]C1=NC2=C([H])C(=C([H])C([H])=C2O1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]O[C@@]1(C(=O)OC([H])([H])C2=C1C([H])=C1N(C2=O)C([H])([H])C2=C3N(C([H])=NC4=C3C(N=C12)=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C2=C(C([H])=C1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C(=NN1C1=C2C(=NC([H])=C1[H])N(C1=C([H])C([H])=C(C#N)C([H])=C1C(F)(F)F)C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])\N=C1\SN(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C2([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C([H])([H])[H]
[H]N([H])C(=O)N([H])C1=C(C([H])=C(S1)C#CC1=C([H])C([H])=C([H])C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C(=O)N([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(O[H])=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C(=N1)N1C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C1([H])[H]
[H]OC1=NC2=C([H])C([H])=C([H])C(N3C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=C([H])C(=C4[H])C4=C([H])SC([H])=C4[H])C([H])([H])C3([H])[H])=C2O1
[H]N([H])C1=C(C#N)C(OC([H])([H])C([H])([H])[H])=NC(N([H])C(=O)C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])[H])=C1[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(N([H])C(=N2)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])N=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C(C#CC3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N=C(C2=C([H])C([H])=C([H])C(C#N)=C2[H])C([H])([H])C1=O
[H]OC1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C2C([H])=C([H])C([H])=C([H])C2=C1\N=N\C1=C2C([H])=C([H])C([H])=C([H])C2=C(C([H])=C1O[H])S(=O)(=O)O[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])SC2=NN=NN2C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1Cl
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(O[H])C([H])=C3[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1C(=O)N(N=C2C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])OC2([H])[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C2=NOC3=C([H])C(F)=C([H])C([H])=C23)C([H])([H])C1([H])[H])C([H])([H])N1C(=O)[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1=O
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])=C1[H]
[H]N=C(C1=C(N([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C(N=C3[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C(OC([H])([H])[H])=C(N([H])S(=O)(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@](=O)(O[H])O[P@](=O)(O[H])OC([H])([H])[C@@]2([H])O[C@@]([H])(C3=NC(=C([H])S3)C(=O)N([H])[H])[C@]([H])(O[H])[C@]2([H])O[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])C([H])=C([H])[H]
[H]OC1=C([H])[C@]2([H])C(=C([H])C([H])([H])[C@@]3([H])[C@]4(C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])[C@]([H])([C@@](O[H])(C(=O)C(\[H])=C(/[H])C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]4(C([H])([H])[H])C([H])([H])C(=O)[C@@]23C([H])([H])[H])C(C1=O)(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(C([H])([H])OC(=O)C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C#N)C1=C(C([H])=C([H])N=C1N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=NN(C([H])=C1C1=C([H])N=C2N=NN(C2=N1)C([H])([H])C1=C([H])C([H])=C2OC([H])([H])C([H])([H])OC2=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C2C(=O)OC([H])([H])C([H])([H])C2=C([H])C2=C1[C@@]1([H])OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N1C(=O)C([H])=C([H])C2=C1C([H])([H])[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@]22N(C(=O)C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(=O)N4C([H])([H])C([H])([H])C([H])([H])[C@]5([H])[C@@]6([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]45C4=C(N([H])C(=O)C([H])=C4[H])C6([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
[H]OC([H])([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N(C(=O)OC([H])([H])[H])C([H])([H])[H])=C1OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N1C2=C(N=C1[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=C(S1)C1=NC(OC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=NC(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=NC(=C(C(=O)N1C([H])([H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C1=NN(C2=C1C([H])([H])C([H])([H])C([H])([H])C1=C(Cl)SC(Cl)=C21)C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])N=C1O2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2Cl)C(=O)N([H])C2=NN(C([H])=C2[H])C2=C([H])C([H])=C([H])C(=C2F)C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2C(=C1[H])[C@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C3N=C(Cl)SC3=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H]
[H]C1=C(N(C(=C1C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])OC3=C(C([H])=C([H])C([H])=C3[H])C(=O)C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C2=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2N(C1=O)C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C(C([H])=O)C2=C1C([H])=C([H])C1=C2C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])SC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C2C(SC3=C2C([H])=C([H])C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])=C3[H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C([H])C2=C1[C@@]13C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]([H])(C2([H])[H])[C@]11C([H])=C([H])[C@]2(OC([H])([H])[H])[C@@]3([H])N=C(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C3[H])[C@]2(C([H])([H])[H])C1([H])[H]
[H]ON([H])C(=O)C1(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[N+]1=C([H])C([H])=C(C([H])=C1[H])N(C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])[N+]1=C([H])C([H])=C(C([H])=C1[H])N(C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H]
[H]C1=NN(C(=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C(C2=C([H])N=NS2)\C(=C(/[H])C2=C([H])N(C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C23)C([H])([H])[H])C1=O
[H]OC(=O)C([H])([H])N(C(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C(C3=C(S2)C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[C@@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])S2)C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H]
CCC1=C(CCCC(O)=O)C=CC=C1C1=NSC(=N1)C1=CC=C(CC(C)C)C(=C1)C#N
[H]N(C(=O)C1=C(C([H])=O)N(C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])C1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(OC(=O)C3=NC([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1=NC([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]OC1=C([H])C([H])=C2C(SC(=C2C([H])([H])C2=C([H])C([H])=C(C(OC([H])([H])[H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C(N([H])C(=O)C([H])([H])N([H])[H])C([H])=C2[H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C([H])([H])[C@]2([H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C([H])C(=C([H])N=C12)C([H])([H])[H]
[H]C1=C(N=C(SC2=NC3=C(N2C([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])C(C#N)=C1C([H])([H])OC([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(S1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=NOC([H])=C1[H]
[H]N1C2=C(N=C([H])C([H])=C2[H])N(C(=O)C([H])([H])[N@@+]2([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])C(=O)C([H])([H])C([H])([H])[C@@]4(N([H])C(=O)C#CC5=C([H])C([H])=C([H])C([H])=C5[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])[C@]([H])(O[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C(N1[H])C(\[H])=C1/C(=O)N([H])C2=C([H])C(N([H])C(=O)N([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C([H])C([H])=C12)C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)C1(C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=NC2=C([H])C([H])=C([H])N=C2N1C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C2C(=C(S1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[C@]([H])(OC([H])([H])[H])O[C@]21C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])[C@@]2(OC([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H]
[H]N1C(=NC(=C1C1=C([H])C2=C(C([H])=C1[H])N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])S1
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C([H])=C(C1=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C(C([H])=C([H])C([H])=C1S(=O)(=O)C([H])([H])[H])C(F)(F)F
[H]N=C(N([H])C1=C(Br)C(SC([H])([H])[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])N(C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])[H])[C@@](O[H])(C([H])([H])[H])[C@]1([H])O[H]
[H]C1=C(SC2=C1C(=NC([H])([H])C1=NN=C(N21)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C#CC([H])([H])N1C(=O)C2=C(C([H])=C([H])C(Cl)=C2[H])C2=C1C([H])=C(Cl)C([H])=C2[H]
[H]OC(=O)[C@]1([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N1C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)O[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])[C@@]([H])(C1=NN=C(N1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N1C([H])([H])C([H])(OC2=C(Cl)C([H])=C([H])C(=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)C1([H])[H]
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[H]O[C@]([H])(C1=C([H])C(OC([H])([H])[H])=C(Br)C([H])=C1OC([H])([H])[H])C([H])([H])N([H])[H]
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[H]OC1=NC2=C([H])C(Cl)=C(C([H])=C2C(OC([H])([H])C([H])([H])[C@@]2([H])N([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=NC([H])=NC([H])=C1[H]
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[H]OC(=O)C([H])([H])N(C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1S[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC(=N1)C([H])([H])[H])C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]N([C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C([H])([H])SC(=S)SC([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C1=C([H])C(Cl)=NC([H])=N1)C1=C(Cl)C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1N([H])C([H])=C2[H])C1=C([H])C(Cl)=C(OC2=C([H])C([H])=C([H])C(OC(F)(F)F)=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(Cl)C([H])=C(N=C2C([H])=C1[H])C(=O)N([H])[H])C(=O)O[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C2=NC([H])=NC(N([H])C3=C([H])C([H])=C([H])C(Br)=C3[H])=C2C([H])=C1[H]
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[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])[C@]([H])(N1C([H])=NC([H])=C1[H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])OC1=C([H])C([H])=C2N(C(=O)N=C(C3=C([H])C([H])=C(C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC1=NC2=C([H])C([H])=C(Cl)C([H])=C2N2N=C(N=C12)C1=C([H])OC([H])=C1[H]
[H]N([H])C(=O)C([H])([H])[C@]1([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC([H])([H])C([H])([H])N2C([H])([H])[H])C([H])([H])C([H])([H])N(C1([H])[H])S(=O)(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(Cl)=C2[H]
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[H]N=C(N([H])[H])C1=C([H])C(=C(SC([H])([H])[H])S1)C1=C([H])SC(=N1)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]ON(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=[N+]([O-])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1C([H])([H])N([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C([H])N(C(=C([H])C1=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=NOC([H])=C2[H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H]
[H]N([H])C1=C([H])C([H])=C([H])C(=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C1C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C2C(SC(C(=O)OC([H])([H])[H])=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N3N=C(C4=C3C([H])([H])C([H])([H])N(C4([H])[H])S(=O)(=O)C([H])([H])[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])=C([H])C(F)=C1[H]
[H]N=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NC2=C([H])C([H])=C3N=C([H])N(C(=O)C3=C2S1)C([H])([H])C([H])([H])[H]
CC(OC1=CC=C(Cl)C=C1)C(=O)NC1=CC=C2OC(=NC2=C1)C1=CC=NC=C1
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C1=C([H])C([H])=[N+](C([H])=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[N+]1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2F)C2=C(C([H])=C([H])C([H])=C2[H])N(C1=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C([H])=C2N1[H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)C1=C([H])C([H])=C([H])O1)C([H])([H])C1=C([H])OC([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])[C@]([H])(OC([H])([H])[C@]1([H])O[H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)OC([H])([H])C1=NC([H])=C([H])S1)[C@@]([H])(C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])N=C([H])S1)C([H])([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])N([H])C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C2=C(OC([H])([H])C1([H])[H])C([H])=C(C([H])=C2[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C([H])C(=NC2=C1[H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC(=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)C(OC2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1(C(=O)N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C2=NS(=O)(=O)C3=C([H])C(F)=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
CC(C)(C)OC(=O)NCCC1CCN(CC1)C1=C2SC(=CC2=NC=N1)C(N)=O
[H]N1C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])N(C3=C([H])N=C([H])C(C#N)=C3[H])[C@@]2([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=O)[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])=C12
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N([H])C([H])([H])[C@]1([H])N(C([H])([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C2=NC(=C([H])C(=C2[H])[N+]([O-])=O)[N+]([O-])=O)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(SC([H])([H])[C@]([H])(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C2=C(N([H])C(=N2)C2=C([H])C([H])=C(Cl)S2)C([H])=C1[H])C1=C([H])C([H])=C(N2C(=O)C([H])([H])OC([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])N=C(C([H])=C([H])[H])C(=C1[H])C1=C([H])C([H])=C2C([H])=NC([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=NN(C2=C1C1=NN=C(N1C([H])=N2)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C(=O)C4=C([H])C([H])=C(C([H])=C4[H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])O2
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=NC([H])=NC2=C1N=C([H])N2[C@]1([H])O[C@]([H])(C([H])([H])OP([O-])([O-])=O)[C@@]2([H])O[C@@]([H])(O[C@@]12[H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2O[C@]3([H])[C@@]([H])(N([H])C(=O)C4=C([H])C(OC([H])([H])[H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]O[C@@](C#CC1=C([H])N2N=C(N=C2C(=N1)N([H])[H])C1=C([H])C([H])=C([H])O1)(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)OC1=C([H])C(Cl)=C(N2C(=O)N([H])C([H])([H])C3=C2C([H])=C([H])C(SC2=C([H])C([H])=C(F)C([H])=C2[H])=N3)C(Cl)=C1[H]
[H]N(C1=NC(=O)[C@]([H])(S1)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(SC(=N2)C([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=NC2=C([H])C(=C([H])C([H])=C2C2=C1C([H])=C([H])N=C2[H])C(=O)OC([H])([H])[H]
[H]N1N=C2C(=O)N(C(=O)C2=C1C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(SS[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=NC2=C(N3C([H])=NN=C13)C(Cl)=C([H])C(Cl)=C2[H]
[H]C1=C([H])C(Cl)=C(OC2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
[H]N([H])C1=N[C@@](C2=C([H])C(=C([H])C(Br)=C2[H])C([H])([H])C(=O)C2=C([H])C([H])=C([H])O2)(C([H])([H])[H])C([H])([H])C([H])([H])S1
[H]N1C(=N[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(=N1)N([H])C(SC1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])=C2C([H])([H])[H]
[H]OC1=C(C([H])=C2N=NN([H])C2=C1[H])C(=O)N([H])C([H])([H])[C@]1([H])N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])N1C(=N[H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O\N=C1/C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C(Cl)=C2[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2[C@@]2(C1([H])[H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C(C([H])=C([H])C([H])=N3)C([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]N1C([H])=NC2=C1C(SC1=C(C([H])=C(C([H])=C1[N+]([O-])=O)[N+]([O-])=O)C(=O)OC([H])([H])C([H])([H])[H])=NC([H])=N2
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NC([H])=C([H])N1C([H])([H])[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)S(=O)(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])[C@]2(C([H])([H])N(C3=C([H])C(Cl)=C(F)C([H])=C3[H])[C@@]2([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N(\N=C1/C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C(=C(O[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
OCC1=CC(OCC(O)CNC2CCN(CC2)C2=NC=NC3=C2C(=CS3)C2=CC=CS2)=CC=C1O
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(F)C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1F
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC(C2=C([H])C([H])=C([H])O2)=C(C#N)C([H])=C1[H]
[H]O[C@]1([H])C2=C(N([H])[H])C3=C(N=C2C([H])([H])C([H])([H])C1([H])[H])C([H])=C(C([H])=C3[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C(Cl)=C1[H])[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H]
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CN(C)CC1=CC=CC=C1SC1=C(CO)C=C([123I])C=C1
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[H][C@@]1(CN(CC2=CN=C3N=C4C[C@]5(CC4=CC3=C2)C(=O)NC2=C5C=CC=N2)C(=O)C(C)(C)C)CCC2=C1C=CC=C2
CCCCN(C)C(=O)CC1=C(N=C2N1C=CC=C2Cl)C1=CC(=C(Cl)C=C1)N(O)=O
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[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])N1C([H])([H])C([H])([H])O[C@]([H])(C([H])([H])OC2=C(OC([H])([H])C([H])([H])[H])C([H])=C(C#N)C([H])=C2[H])C1([H])[H]
CCCCCC[Se](=O)CC(C)=O
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[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C2=C(SC([H])=C2[H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C([H])C(OC3([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])C([H])=C2N=C1C([H])([H])C([H])([H])[H]
[H]O\N=C(/C1=C([H])C([H])=C(C([H])=C1[H])C(=O)O[H])C1=C([H])C2=C(C([H])=C1Br)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3C([H])([H])SC2=C([H])C([H])=C([H])C([H])=C2Br)[C@]([H])(O[H])[C@]1([H])O[H]
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[H]N(C(=O)C([H])([H])C(N([H])C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)(C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C([H])N=C2C(=N1)C([H])([H])C([H])([H])[H]
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[H]N(C1=C([H])C([H])=C(C2=NC(C3=C(OC([H])([H])[H])C([H])=C(C([H])=C3OC([H])([H])[H])C([H])([H])OC([H])([H])[H])=C(C([H])=C12)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N1C(=O)C2=C(C1=O)C1=C(C([H])=C([H])C3=C1N(C([H])=C3[H])C([H])([H])[H])C1=C2C2=C(C([H])=C(OC([H])([H])[H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(O[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(OC([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N1N=C(C(=C1C([H])([H])[H])C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=N1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C(=C([H])N1[H])C1=NN([H])C([H])=C1C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]1=C(C([H])=C(C([H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[Cl-].[Cl-].[H][C@@]12C[C@@H]3C[C@@H](C3(C)C)[C@]1(C)OB(O2)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CNC[C@H]1C1=CC=CC(=C1)C(F)(F)F
[H]N(N([H])C1=C2C([H])=C([H])C([H])=NC2=C([H])C([H])=C1[H])C(=O)C1(C2=C([H])C([H])=C([H])C(F)=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(I)C([H])=C(C([H])=C1I)C([H])([H])C1=C(N=C(N=C1[H])N([H])[H])N([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C2=C(C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]S\C(=N\C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H]
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[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(F)=C1[H])C1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1([H])[H])C1=C3C([H])([H])C([H])([H])C2=NN(C([H])=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12OC([H])([H])[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(N=C2[H])N2C([H])([H])C([H])([H])N([H])[C@]([H])(C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C(F)=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C2=C(N([H])C3=C2C([H])=C([H])C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H])C([H])([H])[H])C([H])([H])C([H])=C(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC([H])([H])C([H])([H])N2C([H])([H])[H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=N1
CC(=O)C1=CC(NS(=O)(=O)C2=CC=C(Cl)C=C2Cl)=CC=C1OC1=CC(Cl)=CN=C1
[H]OC(=O)C([H])([H])N1C(=O)N(C2=C([H])C([H])=NC([H])=C2C1=O)C([H])([H])C1=C([H])N(C2=C1C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)C1=C([H])C(=C([H])C([H])=N1)C1=C([H])C(=NC([H])=C1[H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C([H])=C2C(=O)N(C(=O)N([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=NN2[C@@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C(C2=NC3=C(C([H])=C([H])C(=C3[H])C(=O)OC([H])([H])[H])N2C([H])([H])[H])=C1C([H])([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C(N(C([H])=N1)C([H])([H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]C#CC([H])([H])SC1=NC2=C(C3=C(S2)C([H])([H])C([H])([H])C3([H])[H])C(=O)N1C([H])([H])[H]
[H]C1=C([H])C(=C([H])S1)C([H])([H])[N+]1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)C1=C([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2S1
[H]ON([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]N([C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C3=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N([H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F)C(=N\C1=C([H])C(F)=C([H])C([H])=C1[H])\C(=O)C([H])([H])[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)N1N=NC(=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C(=N1)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])C([H])([H])[C@@](O[H])(C([H])([H])C4=C([H])C([H])=C(C([H])=C4[H])C4=C([H])C([H])=C([H])C([H])=C4[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
[H]OC1=NC2=C([H])C(Cl)=C(C([H])=C2C(OC([H])([H])C([H])([H])[C@@]2([H])N([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])[N+]([O-])=O
[H]C1=C([H])C([H])=C(OC2=C(C([H])=NC(F)=C2[H])N(C(=O)C([H])([H])[H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC([H])=C(Cl)C(=N1)N([H])C1=C(F)C([H])=C([H])C([H])=C1C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C2N(C(=O)C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])OC2=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C(C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)N([H])C([H])([H])C([H])([H])[H])C(=C23)C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C(OC(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C(OC([H])([H])C([H])([H])[H])=C1[H])C(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]3([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C4=C([H])C([H])=C(O[H])C([H])=C4[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)O[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(C([H])=C1C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]\C(=C1\SC(=O)N(C1=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(OC(=O)C([H])([H])[H])=C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])Br)C([H])=C1[H]
[H]N1N=C(C2=NC([H])=C([H])S2)\C(=C(/[H])C2=C([H])N(C3=C2C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2F)=C([H])C([H])=C3[H])C([H])([H])[H])C1=O
[H]N1C(=O)C(C2=C(N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[H])=C(C1=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=C1[H])C1=NN=C(N1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=NC(=N3)N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C2=NC(=C([H])N=C12)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(C1=O)C1=C(C([H])=C([H])C3=C1N(C([H])=C3[H])C([H])([H])[H])C1=C2C2=C(N1[H])C([H])=C(C([H])=C2[H])C([H])([H])[H]
[H]N(C(=O)C1=NOC2=C1C([H])([H])C([H])([H])C1=C2C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(N(C3=C([H])N=C(OC([H])([H])[H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(C(F)=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
ONC(=O)CNS(=O)(=O)C1=CC=C(OCC2=C(Cl)C=C(F)C=C2)C=C1
[H]OC(=O)C([H])([H])SC1=NC(Cl)=C([H])C(=N1)N([H])C1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(Cl)=C(S1)C1=NC(=NO1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC(=C(N=C1C([H])([H])C([H])([H])[H])N([H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])F)C([H])([H])C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=N1
[H]N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1C([H])([H])N([H])C(=O)C([H])([H])C1=C(C#N)C([H])=C([H])C(N([H])C([H])([H])C(F)(F)C2=NC([H])=C([H])C([H])=C2[H])=[N+]1[O-]
[H]ON([H])C(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(C([H])=N1)C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]N(C([H])([H])C1([H])C([H])([H])C1([H])[H])C1(C(=O)N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C(=C([H])C([H])=C3F)C([H])([H])C3=NN([H])C(=O)C(=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]3([H])C([H])([H])C1=C([H])C([H])=C(OS(=O)(=O)C(F)(F)F)C(OC([H])([H])[H])=C21
[H]N([H])C1=NC([H])=C2C([H])=C(C(=NC2=C1[H])N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(SN=C2C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C(=O)C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])=C1[H]
CCCCCCCCS(=O)(=O)NC1=CC(SC2=NC=NN2)=C(O)C2=CC=CC=C12
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[H]N1C(=O)C([H])=C(C2=C([H])C([H])=C(F)C(F)=C12)C([H])([H])N(C1=C([H])N=C([H])C([H])=N1)C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
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[H]N([H])C1=C([H])C(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(N([H])[H])C2=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1C2=O
[H]N(C(=O)C1=C(N([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])OP(=O)(O[H])O[H])[C@@]1([H])O[H])N1C([H])=C([H])C(=O)N=C1OC([H])([H])[H]
[H]N1C2=C([H])C3=C(C([H])=C2[C@@]([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C(=C([H])C(=O)O3)C(F)(F)F
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[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C1=C([H])C([H])=C([H])C(=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])([H])C([H])([H])C2([H])[H]
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[H]N(C(=O)C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C(F)(F)F
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[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])N(C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])=C12)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C(OS(=O)(=O)C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N([H])[C@](C1=C([H])N=C([H])N1C([H])([H])[H])(C1=C([H])C([H])=C(C#N)C(OC2=C([H])C([H])=C([H])C(=C2[H])[C@]2(C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C(F)C([H])=C(OC2=C(N([H])S(=O)(=O)C3=C(Cl)C([H])=C(OC(F)(F)F)C([H])=C3[H])C([H])=C(C([H])=C2[H])C(=O)N([H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]C1=C([H])N=C(S1)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C2N(C(=NC2=C1C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]O[C@](C([H])([H])N([H])C1=C([H])C([H])=C([H])C2=NC([H])=C([H])C([H])=C12)(C([H])([H])[C@@]1(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(F)(F)F
[H]N(C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C([H])S1
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@]1([H])C([H])([H])O[C@@]([H])(O[C@]1([H])C1=C(O[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H])\C1=C([H])N=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])SC2=NC3=C(C4=C(S3)C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C(=O)N2C([H])([H])C([H])=C([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=NC([H])=NC(N([H])C3=NN([H])C(=C3[H])C([H])([H])C(=O)N([H])C3=C([H])C(F)=C([H])C([H])=C3[H])=C2C([H])=C1OC([H])([H])[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C1([H])[H])C([H])([H])OC(=O)C1=C(C([H])=C(C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@@]([H])(C2=C([H])C([H])=C(Br)C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]ON(C(=O)[C@]([H])(C1=C([H])C([H])=C2C([H])=C(OC([H])([H])[H])C([H])=C([H])C2=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2C([H])=C([H])N([H])C2=C1[H])C1=C(C#N)C([H])=NC([H])=C1C1=C([H])C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C(Cl)C(=C(Cl)C([H])=C1[H])C([H])([H])OC1=C2N=C(C([H])=C(C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC2=C([H])C(C#CC([H])([H])N3C([H])([H])C([H])([H])C(=C([H])C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])C3([H])[H])=C([H])C([H])=C2N1[H]
[H]OC1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C2C([H])=C([H])C(Cl)=C([H])C2=N1)C([H])([H])C([H])([H])C1=NN([H])N=N1
[H]N([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C([H])C2=C(C([H])=C1[H])C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C2[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C(=C1C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C(=C1Cl)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])N(N=C12)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])S1
[H]O\C(OC([H])([H])[H])=C1/N(C2=C([H])C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])(C4=C([H])C(OC([H])([H])[H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])=C([H])C([H])=C2[H])C(C(=O)OC([H])([H])[H])=C(N=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
CCNC1=CC(=CC(COCC2(CCN(C)CC2)C2=CC=C(F)C=C2)=N1)C(F)(F)F
[H]N1C(=C([H])C2=C1C(=C([H])C([H])=C2[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1N=C([H])C(=C1C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C2N=C(C(=NC2=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])OC1=NC([H])=C(C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F
OC1=CC(O)=C(C=C1)C1=NN=C(S1)C1=CC=C(C=C1)C(F)(F)F
[H]N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C(=N[H])N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C1=NC2=C(C([H])=C([H])C(=C2[H])C(=N[H])N([H])[H])N1C([H])([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(N=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C2([H])[H]
[H]N(N([H])C(=O)C1=C([H])C([H])=C(O1)C([H])([H])N1N=C(C(Cl)=C1C([H])([H])[H])[N+]([O-])=O)C(\[H])=C1/C([H])=C(Cl)C([H])=C([H])C1=O
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(O[H])[C@]([H])(N([H])[H])C([H])([H])SC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1C#CC1=C([H])N=C([H])N=C1N([H])C1=C([H])C(Cl)=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1C(=O)N(C([H])([H])C1(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C(=NO2)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
CN1N=C(C)C(C(=O)N2CCCCC2C2=CC=CN=C2)=C1OC1=CC=CC(Cl)=C1F
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])O1)C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N
[H]N(\N=C(/[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2OC1=O
[H]OC1=C([H])\C(=N\C2=C3C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C3=NC([H])=N2)C(=O)C([H])=C1OC([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C1=NC(=C([H])S1)C([H])([H])C1=NN=C(SC([H])([H])SC2=NN=C(N2N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])SC(=N2)N([H])C([H])([H])C([H])([H])C(=O)O[H])N1N([H])C(=O)C([H])([H])[H]
[H]OC(=O)C(\[H])=C(\C(\[H])=C(/[H])[C@]1([H])N(C2=C([H])C3=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])/C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(F)C([H])=C1C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]2([H])N3C4=C(SC([H])([H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C4[C@]2([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])N(C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])N=C(S1)C1=NC(=NC2=C1SC([H])=C2[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])C2([H])[H])C1=C([H])C([H])=C(O[C@]2([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(N=C([H])C([H])=C1[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])=C(C([H])=C2[H])C([H])([H])OC1=C(C(=C([H])C([H])=C1[H])C1(OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC3=C(N=C([H])N3C([H])(C([H])([H])[H])C([H])([H])[H])C(=N2)N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])N([H])C(=O)C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C1([H])[H]
[H]C1=C2N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1C(=N[C@@]2([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)N(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])C([H])=C3Cl)C([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])[H]
[H]C1=NN(C(=O)C(Cl)=C1OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N1C(=C([H])C2=C([H])C([H])=C(Br)C([H])=C12)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]1(N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=C(C#CC([H])([H])[H])C(=NC2=C(C([H])=NN12)C1=C([H])N(N=C1[H])C([H])([H])[H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C1=C([H])C([H])=C([H])C2=C([H])C([H])=C(N=C12)C1=NN=C2C([H])=C([H])C([H])=C([H])N12)C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C(=C(F)C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])[H])C([H])([H])N([H])C2=C(OC([H])([H])[H])C([H])=C([H])C(=C2[H])C([H])([H])[H])=N1
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C2=C(N([H])C(=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2[C@@]1([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@@](=O)(O[H])O[P@](=O)(O[H])OP(=O)(O[H])O[H])[C@@]1([H])O[H])N1C([H])=C([H])C2=C(C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C1=O
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C(=N1)N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C3=C(C([H])=C([H])C([H])=C3[H])N(C1=O)C([H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]OC(=O)[C@]([H])(O[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])[C@]([H])(OC([H])([H])C1=C(C([H])=C(C#N)C(=O)N1C([H])([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(C#N)C(Cl)=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C3=C([H])C([H])=C([H])C([H])=C3SC3=C2C([H])=C(C([H])=C3[H])C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(\N=N\C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C([H])C(N([H])C2=NC(=C([H])C([H])=N2)C2=C([H])C([H])=C([H])N=C2[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1(SC([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(N=[N+]=[N-])C(I)=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])S[H])C([H])([H])C(=O)N([H])[H])[C@]([H])(O[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C([H])=N1)N(C([H])=C2C1=C([H])C(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3S2)=C2N([H])N=C([H])C2=C1[H])C([H])([H])C([H])([H])N([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C([H])C([H])=C(C([H])=C12)C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C(C([H])=C(O[H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C3=C(O2)C([H])=C([H])C([H])=C3[H])C1([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])[H])C(=C([H])C(=C2[H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H]
[H]N1C(=O)S\C(=C(/[H])C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C1=O
[H]N1C([H])=C(C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C2N=NN(C2=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2F)C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])=C(S1)C(=O)O[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=C([H])N=C1C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H]
[H]N(C(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C(=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(N([H])C(=O)N([H])C2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C2=NN=C(N2C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(O[H])C([H])=C1C([H])([H])C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C(C(OC([H])([H])C(=O)O[H])=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C(C(OC([H])([H])C(=O)O[H])=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])O[H]
[H]N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C([H])([H])C([H])([H])C([H])([H])C3=C([H])N([H])C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=N3)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])N([H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(C2=C([H])N=C(N2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C(F)C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])[C@]2([H])[C@]3([H])C([H])([H])C([H])([H])[C@]4([H])N([H])C(=O)C([H])=C([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
COC1=C(C)C=NC=C1C1=CC2=C(C=C1F)N1C(C)=NN=C1CC2
[H]N(C(=O)C1=C([H])N=C2SC([H])=C([H])N2C1=O)C1=NOC([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]3([H])C([H])([H])C1=C2C(OC(=O)C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N(C(=O)[C@]([H])(N([H])C(=O)C2=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])=C([H])C(=C2[H])C([H])([H])N([H])C1=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C(=C(N([H])C(=O)C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C2C(SC(=C2C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])=NC([H])=N1
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])=[N+](C([H])=C2[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)N([H])C2=C3C(=O)C4=C(N([H])N=C4C3=C([H])C([H])=C2[H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[H]
[H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C([H])C([H])=C2O1
[H]OC(=O)C1=C([H])N=C(C([H])=C1[H])N(C1=C([H])C(OC([H])([H])C(F)(F)F)=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])[C@]([H])(C(=N\OC([H])([H])C(=O)OC([H])([H])[H])\C([H])([H])N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C(=N1)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]N([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(N2[H])N(C(=O)N(C3=O)C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C(=O)N1C([H])([H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C2C(SC(=C2C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])=C2[H])C([H])([H])[H])=NC([H])=N1
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N2N=C([H])N=C2C([H])=C1C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=NN2[C@@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C(C2=NC3=C(C([H])=C([H])C(=C3[H])C([H])([H])[H])N2C([H])([H])[H])=C1C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C1=C([H])C(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])S[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C(OC([H])([H])[H])=C2[H])C2([H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]N([H])C1=C(SC(=S)N1C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC([H])=C([H])N1[H]
[H]N(C(=O)SC([H])([H])[H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C([H])([H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(SC2=C([H])C([H])=C(Cl)C([H])=C2[H])=NN(C1=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=C(C2=C1C(=O)N(C(=N2)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(=C(O[H])C(=C1[H])C1=NC2=C([H])C(=C([H])C([H])=C2N1[H])C(=N[H])N([H])[H])C1=C([H])C(F)=C([H])C([H])=C1O[H]
[H]C1=NC(OC2([H])C([H])([H])N(C(=O)C3=C([H])N=C(C([H])=C3[H])C([H])([H])[H])C2([H])[H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C(SC2=C1C(=O)N(C(=O)N2C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C2C([H])=C([H])C([H])=C([H])C2=NC(=N1)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C2=C(N=C1[C@]([H])(N1C([H])([H])C([H])(OC3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])[H])N(N=C2[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[S@@](=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])OC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1=O
[H]N([H])C1(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2N=C([H])N3[H])C([H])([H])C1([H])[H]
[H]C([H])([H])N(C([S-])=S)C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=O)C2=C(O1)C([H])=C1OC([H])=C([H])C1=C2OC([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NO1)[C@]([H])(C(=O)N([H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC([H])([H])C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Br)=C([H])C([H])=C2C(=O)N1C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
COC(=O)[C@H](C1=CC(OC)=CC=C1)[C@@]1(C)CCCCN1
[H]\C(=C1/C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OP(=O)(O[H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C(=C([H])C([H])([H])C1([H])[H])N1N=C(C2=C(N=C([H])N=C12)N([H])[H])C1=C([H])C([H])([H])[C@@]([H])(C([H])=C1[H])C([H])([H])[H])P(=O)(O[H])O[H]
[H]OC1=C(F)C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(Cl)=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C2=NC([H])=C(C([H])=C12)C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]N1C(=C([H])C2=NC(OC([H])([H])[H])=NC(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N2C([H])([H])C([H])([H])S(=O)(=O)[C@@]12[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])[C@@]1([H])C([H])([H])C([H])([H])[N@+]([H])(C([H])([H])C2=C(OC([H])=C2[H])C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(SC2=C(N([H])C3=C2C(=O)N([H])C(=N3)N([H])[H])C([H])([H])[H])C([H])=C1[H])C(=O)O[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])N2N=C([H])C(C#N)=C(N([H])C3=C([H])C([H])=C(OC4=C([H])C([H])=C([H])C(OC([H])([H])[H])=C4[H])C([H])=C3[H])C2=C1C([H])([H])[H]
[H]C1=C(N=C(S1)C([H])([H])[H])C#CC1=C([H])C(Br)=C([H])C(Br)=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])N1N=NC(=C1[H])C([H])([H])OC1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=NC2=C([H])C([H])=C(N=C2C(=N1)C1([H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])[C@]([H])(C2=C(F)C([H])=C(F)C(F)=C2[H])[C@@]([H])([N+]([H])([H])[H])C1([H])[H]
[H]N1C(=O)N(C2=C(N(C(S[C@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])=N2)C([H])([H])C(\[H])=C(/Cl)C([H])([H])[H])C1=O)C([H])([H])[H]
[H]C1=NN(C([H])=C1C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O\C(OC([H])([H])C([H])([H])[H])=C1\C(=NC(C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)=C(C(=O)OC([H])([H])C([H])([H])[H])[C@@]1([H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(C1=NN(N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(N(N=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])[C@@]([H])(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(N([H])C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(N=C2[H])N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)[C@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
CN[C@@H](C)C(=O)N1CCN(CC1)C1=NC(=NC(=N1)N1CCOCC1)N1C(=NC2=CC=CC=C12)C(F)F
[H]N([H])[C@]([H])(C([H])([H])[H])C([H])([H])N1N=C([H])C2=C([H])C([H])=C3OC(=C([H])C3=C12)C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(=O)OC([H])([H])C([H])([H])[H])C1=NC([H])=C([H])C(=N1)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C([H])N=C1[H])C1=NC([H])=C2N([H])N=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
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[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])\N=C(/S[H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])[C@@]([H])(C([H])([H])[H])C1(C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])C#N)C1=C([H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])C2=C1[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C2C(=C1[H])C1=C(C([H])=C(O[C@@]3([H])C([H])([H])[N@]4C([H])([H])C([H])([H])[C@]3([H])C([H])([H])C4([H])[H])C([H])=C1[H])C2([H])[H]
[H]N(N(C(=O)N([H])[C@@]([H])(C1=NC([H])=C(C([H])=C1F)C1=C([H])C(Cl)=C([H])C(Cl)=C1C1=NOC(=N1)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)C(F)(F)F
[H]N(C(=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Br)C(=C1[H])N1N=C(N(C1=O)C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@]([H])(C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C(C([H])=C(Br)C([H])=N2)C([H])([H])C([H])([H])C2=C1C([H])=C([H])C(Cl)=C2[H]
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@]2([H])OC([H])([H])[H]
[H]C1=C(C([H])=C(S1)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]2(O[H])C(=O)C([H])([H])SC2=NC([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C(=O)C([H])=C([H])[C@]3(C([H])([H])[H])[C@@]12[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3C([H])([H])SC2=C([H])C([H])=C([H])C([H])=C2F)[C@]([H])(O[H])[C@]1([H])O[H]
[H]C1=NC(=C([H])C([H])=C1Br)C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
C\C(=N/OCC1=CC(=C(C=C1)C1CCCCC1)C(F)(F)F)C1=CN=C(CNCCC(O)=O)C=C1
[H]OC1=C([H])C([H])=C(C([H])=C1Cl)C(=O)N([H])\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N([H])[C@@]2([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C(=C2C3=NC([H])=C([H])C([H])=C3C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]SC([H])([H])[C@@]([H])(C(=O)N([H])C1=C([H])C(=C([H])C([H])=N1)C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C1=C([H])C(Br)=C([H])C(=C1N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])[C@@]([H])(C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C([H])([H])[H])C([H])([H])C1=C(OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])=C(N=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C(O[H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C(=O)OC3=C2C([H])=C(Cl)C([H])=C3[H])[C@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N([H])C1=NC(N([H])C2=C([H])C(Br)=C([H])C([H])=C2[H])=C2C([H])=C(N([H])C2=N1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(=C([H])S1)C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC2=C3C(F)=C([H])N(C3=NC([H])=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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COC1=CC=C(C2=CC(=NN12)C(F)(F)F)C1=NN(CCCOC2=CC=C(C=C2)C2=NNC(=O)CC2C)C(=O)CC1C
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C(I)C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(N([H])C2=C([H])C(Cl)=C(C([H])=C2[H])C([H])([H])[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2\C(=N\C(=O)C3=C([H])C([H])=C(F)C([H])=C3[H])N([H])C3=C([H])C([H])=C(C([H])=C23)C([H])([H])N2N=C([H])N=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])S[C@@]([H])(C2=C(OC([H])([H])[H])C([H])=C(Cl)C(=C2[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
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[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)S(=O)(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1C([H])=C(F)C(=C2[H])C(F)(F)F)C(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C#N)=C1C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C3=C2C([H])=C([H])C([H])=C3N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=C(C(=O)[C@@]2([H])N([H])[C@]([H])(SC2([H])[H])C2=C([H])C([H])=C([H])N=C2[H])C2=C1C([H])=C(OC([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])=C2[H]
[H]C1=C([H])C(Cl)=NC(=C1[H])C1=C([H])N=C2N=C(OC2=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C(\N=N\C2=C(O[H])N(N=C2C([H])([H])[H])C2=C([H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C(O[H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C(C([H])=NC2=C(C([H])=C([H])C([H])=C12)C([H])([H])[H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1N=C2SC(=C([H])N2C1=S)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
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[H]N([H])C(C(=O)N([H])[C@@]([H])(C1=NN(N=N1)[C@]([H])(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C([H])([H])[C@@]12C3=C([H])C([H])=C([H])C([H])=C3[C@@]([H])(C3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H]
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[H]N([H])C([H])([H])C([H])([H])O\N=C(\C1=C([H])C([H])=C([H])C(=C1[H])C(N([H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C(=C1[H])[N+]([O-])=O)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])C1=C([H])C([H])=C2N(C([H])([H])C([H])([H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C2=C1[H])C1=C([H])C([H])=C([H])S1
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])C([H])=C2N([H])C([H])=C([H])C2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(I)=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
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[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(I)C([H])=C2[H])C([H])=C1[H]
[H]N1N2C(N=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])=NC(=C(C2=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])C2=C([H])C(O[H])=C(C(=O)O2)C2=C(\C([H])=C(/[H])C3=C([H])C4=C(C(=O)O3)C3=C(C([H])=C(O[H])C(O[H])=C3[H])C(=O)O4)C([H])=C(O[H])C(O[H])=C2[H])C([H])=C1O[H]
[H]C1=C(C(=NN1C([H])([H])C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(S1)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1N=C(C2=C([H])C([H])=C(SC([H])([H])[H])N3N=C(C([H])=C23)C([H])([H])C([H])([H])[H])C(C1=O)(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(F)=C2[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C([H])([H])OC2=C([H])C([H])=C3C(C(=O)N([H])C3([H])[H])=C2C1([H])[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(/[H])C2=C([H])C(Cl)=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(O[H])C(=NC2=C([H])C([H])=C(F)C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CN(CC1=CC=C(C=C1)C1=NCCN1)C(=O)CCCN(C)S(=O)(=O)C1=CC=C(Cl)C(C)=C1Cl
[H]OC(=O)[C@@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C(\[H])=C(/[H])C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C2[H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=S)N([H])N([H])C2=C(F)C(F)=C(F)C(F)=C2F)C([H])=C1[H]
[H]N=C(N([H])[H])[C@]1([H])N([H])C([H])([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])=C(C(=NC1=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])C2=NC3=C(N2[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(N=C(N=C1O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C(I)C(=NC(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C(Br)=C([H])C([H])=C2C([H])=C1OC([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2N([H])C(=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]N(C(=O)C1=C2N=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(=NC2=C(C(=NN12)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1Cl)C([H])([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)O[C@]1([H])C2=C(C([H])=C3OC([H])([H])OC3=C2[H])[C@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])[C@]2([H])C(=O)OC([H])([H])[C@@]12[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])[C@]1(N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@](C([H])([H])N([H])C(=O)C1=C(N([H])[H])N(N=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]N([H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(N(C([H])([H])[H])S2(=O)=O)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C(\[H])=C(/[H])C1=C(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1N=C(C(=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@](C1=NC([H])=C(Cl)C([H])=C1[H])(C1=C([H])C(=C([H])C(F)=C1[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN(C([H])=N1)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C(=O)N1[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=NC2=C1C([H])=C([H])C(=N2)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C([H])C2=C([H])C([H])=C(C([H])=C12)[C@]([H])(N1C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C([H])C([H])=N2)C1=O)C([H])([H])[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C(F)(F)F
[H]OC([H])([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NN=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1(C2=NC([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])[C@@]([H])(C([H])([H])[H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C(=C(OC([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(SC2=C1C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N1C(=O)C2=C([H])C([H])=C(F)C([H])=C2N=C1C([H])([H])[H]
[H]C1=C([H])N2N=C(N=C2C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C(N=C2N([H])C([H])([H])C([H])([H])N2[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])[C@@]([H])(C([H])(F)F)[C@@]2([H])OC([H])([H])C(=O)[C@@]12[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(N=C([H])C([H])=C2[H])N(C(=O)C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C2N([H])C(=O)OC2=C1[H]
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C3=C([H])C([H])=C(O[H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1=O
[H]N([H])C(=O)C1=C2C(OC([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3=C([H])N([H])C4=C3C([H])=C(F)C([H])=C4[H])C2([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])SC([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C2=NC([H])=C([H])C([H])=C2[H])=C1[H]
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[H]N([H])[C@]([H])(C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1=NN(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=N2)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C(C(=O)N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])N1C([H])([H])C(=O)N(C2=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(N([H])C(N([H])[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])=C2C(=O)OC([H])([H])C([H])([H])[H])C([H])=C1[H]
COC1=CC=CC=C1C1=C2C=CC(OC3=CC=C(F)C=C3F)=NN2C=CC1=O
[H]C1=C([H])C(=C([H])C([H])=C1F)[C@]1([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])N(C(=O)N(C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])S1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O\N=C1\C(\N([H])C2=C\1C([H])=C([H])C([H])=C2[H])=C1\C(=O)N([H])C2=C([H])C(Br)=C([H])C([H])=C12
[H]N(C(=O)C([H])([H])[H])C([H])([H])C1(C2=C([H])N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2=O)C([H])([H])C([H])([H])N1C(=NC2(C1=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C1=C(O[H])C2=C(C([H])=C([H])C(=C2[H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])O[H])N(C1=O)C([H])([H])[H]
CCC1=C(CCCC(O)=O)C=CC=C1C1=NSC(=N1)C1=CC=C(N2CCN(C)CC2)C(=C1)C(F)(F)F
[H]OC1=C(O[H])C([H])=C(\C([H])=C(/[H])C(=O)C2=C([H])C(=C([H])C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(=O)OC([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=O)N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])C2=O)C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C(Cl)C(=C([H])C(=C1[H])[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])Br)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C2C(N([H])C(=O)\C2=C(\[H])C2=C([H])C([H])=C([H])N2[H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])N=C2C([H])=C(N([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(OC([H])([H])[H])=C([H])C2=C1N([H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N([H])N([H])[C@@]([H])(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C2=C(N([H])C(=O)C([H])=C2C(F)(F)F)C([H])=C1[H])C([H])([H])C(F)(F)C(F)(F)F
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])[C@@]4([H])C3([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(N([H])C(=N[H])N([H])[H])=C([H])C([H])=C2[H])C(F)=C1[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N3C(=O)C([H])([H])C4(C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]OC1=C([H])C(\C([H])=C(\C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C([H])([H])[H])=C([H])C(O[H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C([H])N=C12)N([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=NOC(=C1[H])C([H])([H])[H]
[H]SC1=NC(=NN1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N(C(=O)N1C2=C(C([H])=C(OC([H])([H])[H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C(=C1[H])C1=C([H])N=C([H])C([H])=C1[H])C(F)(F)F
[H]C1=NC(=C([H])C([H])=C1[H])C1=NOC(=N1)C1=C([H])C([H])=C(OC(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(\N=C(/[H])[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
COC1=CC(\C=C2/CCC\C(=C/C3=CC=C(F)C=C3)C2=O)=CC(OC)=C1
[H]OC([H])([H])C([H])([H])N([H])C1=C([H])C(=NC(=C1[H])C([H])([H])[H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@](N([H])C(=O)C(F)(F)F)(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])=O)N([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C(N=C(N([H])[H])N([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C(Cl)C(=C(Cl)C([H])=C2[H])C([H])([H])OC2=C3N=C(C([H])=C(OC([H])([H])[H])C3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C(S2)C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(S1)C(=O)C([H])([H])[H])C1=C(C(=NC2=C([H])C([H])=NN12)N([H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C1=NC(=C(S1)C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C([H])=C([H])C2=C1C([H])([H])[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]2(\N=C(/[H])C2=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C2[H])\C1=C(/[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])S1)C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC2=C(C([H])=C([H])C(=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C4=C([H])C([H])=C(C#N)C([H])=C4C([H])([H])C([H])([H])[C@]23[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]