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[H]C1=C([H])N2C(=C1[H])C(=O)[C@](OC1=C([H])C([H])=C([H])C([H])=C21)(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
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[H]C1=C(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])\C1=[N+]1/C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])[H]
[H]O[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C1([H])[H])C([H])([H])[C@@](N([H])C([H])([H])C(=O)N1[C@]([H])(C#N)C([H])([H])C([H])([H])[C@]1([H])C#C[H])(C3([H])[H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N(C(=O)O[C@@]2([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C12
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[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1C1=C(C([H])=C(C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C(=O)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]1([H])C(C(=O)OC([H])([H])[H])=C(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C2([H])[H]
[H]C1=NC([H])=C(OC([H])([H])[C@@]2([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C3=C(C([H])=C2[H])N(C(=O)C3=C(C#N)C#N)C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=NC(=C([H])C([H])=N1)C1=C([H])C2=C(N1C([H])([H])C(F)(F)F)C([H])([H])C([H])([H])N([H])C2=O
[H]N([H])C1=NC(=NN1C1=NC([H])=C([H])C([H])=C1[H])N([H])C1=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])[H])=C1[H]
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[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]\C(=N/C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C(N(N=C1C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])=C([H])C([H])=C1C(=O)OC([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(\C(SC([H])([H])C1=C([H])SC2=NC([H])([H])C([H])([H])N12)=N\C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C(=N2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@]([H])(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@@]1([H])N([H])C2=C(C([H])=C(OC(=O)C3=C(Cl)C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H]
[H]C1=C(OC([H])([H])[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]21[H]
[H]N(C1=C(Cl)C(=O)C(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])=C(Cl)C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C(Cl)C([H])=C2[H])C2=C([H])N(N=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@@]([H])(C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C([H])=C([H])[C@@]3([H])C([H])([H])[C@@]([H])(O[H])C([H])([H])[C@]([H])(OC(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]23[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(F)=C(C(=C1[H])C1=C([H])C2=NN=C(N2N(C1=O)C([H])([H])[H])C1=C(F)C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])O[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])O[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])SSC1([H])[H])C([H])([H])O[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]C1=C([H])C(F)=C([H])C2=C1ON=C2C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])SC2=NN=C(S2)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC(C2=C([H])C([H])=C(O2)C([H])([H])[H])=C(N=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])SC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C2=NC3=C(N2[H])C([H])=C([H])C(=C3[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(N([H])[H])=C2C([H])=C([H])N=C([H])C2=N1
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C2=C(N=C(N([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=NC([H])=C(N([H])C2=C3C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C3=NC([H])=N2)C([H])=N1
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[H]OC1=C(C(=O)N([H])C([H])([H])[C@]2([H])N(C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C(Cl)C([H])=C1C([H])([H])C([H])([H])[H]
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[H]N(C1=NC(=NC([H])=C1C1=NN([H])N=N1)N([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C1=NC([H])=C(C2=C1C(=C([H])S2)C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])SC2=NN=C3C(=N2)N(C2=C3C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])=C([H])[H])C([H])=C1[H]
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[H]N([H])C(=O)C1=C([H])N=C2C(C([H])=C([H])C([H])=C2C([H])([H])[H])=C1C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C1[H]
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[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C(OC([H])([H])[H])C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
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[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(N([H])C(=O)[C@@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N=C(N([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C(=O)C([H])([H])N2C(=O)[C@@]([H])(N([H])S(=O)(=O)C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3F)C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C([H])=C2[H])=C1[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(Cl)C([H])=C([H])S1)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C2(OC([H])([H])C3=C4C([H])=C([H])C([H])=C([H])C4=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C([H])=C1C(=O)C([H])=C2C([H])([H])C([H])([H])[C@@]3([H])[C@@]4([H])C([H])([H])C([H])([H])[C@@](OC(=O)C([H])([H])[H])(C([H])([H])[H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C1([H])[H]
[H]\C(=C(/[H])[N+]([O-])=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(OC2=C(C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(O[C@]2([H])C([H])([H])N(C(=O)C([H])([H])[H])[C@@]([H])(C(=O)N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C3([H])[H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C2([H])[H])=C([H])C(F)=C1[H]
[H]OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2[C@@]([H])(N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])[N+]([O-])=O
[H]ON=C1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@]([H])(N(O[H])C([H])=O)C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[S@@](=O)C1=NC2=C([H])C(=C([H])C([H])=C2N1[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N1C([H])=C(N=C(N([H])C([H])([H])C2=NON=C2C([H])([H])[H])C1=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC2=C1C([H])=C(F)C(F)=C2[H])N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C(N=C(S1)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]1([H])N(C(=O)[C@@](N([H])C(=O)ON2[C@@]3([H])C([H])([H])[C@@]4([H])C([H])([H])[C@]2([H])C([H])([H])[C@@]([H])(C3([H])[H])C4([H])[H])(C([H])([H])[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]([H])(OC2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N1C(=NC2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]ON([H])C(=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)S(=O)(=O)C1=C([H])C([H])=C([H])C(N([H])C(=O)N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])=C1[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(C(OS(=O)(=O)C(F)(F)F)=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N=C([H])N=C2O1)N1C([H])([H])[C@]2([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=NOC(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N1OC(=O)C(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
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[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC(=O)C1=C([H])C([H])=C(C(I)=C1[H])C([H])([H])[H]
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[H]\C(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])=C1/C(=O)C2=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C2OC1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C(=NN1C([H])([H])C1=C([H])C([H])=C(C([H])=C1Cl)C(F)(F)F)C1([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@]1([H])N([H])C(=O)N(C1=O)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=NC(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=C(\C([H])=C2/SC3=C([H])C([H])=C([H])C([H])=C3N([H])C2=O)C2=C1C(=C([H])C([H])=C2[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(N(C3=NN(N=N3)C([H])([H])[H])C([H])([H])C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C2=C([H])C(=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)O[H])C1=C([H])C(C2=NC3=C([H])C(=C([H])C([H])=C3N2[H])C(=N[H])N([H])[H])=C(O[H])C(=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])O[H]
[H]OC(=O)C1=C(OC([H])([H])C(=O)O[H])C(Br)=C(S1)C1=C([H])C(N([H])C2([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C(C2=C([H])C([H])=C([H])S2)\C(=C(/[H])C2=C([H])N(C3=C2C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C3[H])C([H])([H])[H])C1=O
[H]N(C(=O)C([H])([H])C(=O)OC1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C(=C1[H])N1N=C(N(C1=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C(=O)[C@]1([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(\C([H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=N[C@]([H])(C([H])([H])[H])[C@]([H])(C([H])([H])N([H])C(=O)C([H])([H])N2C(=O)C(N([H])S(=O)(=O)C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])N1[H]
[H]O\C(OC([H])([H])C([H])([H])[H])=C(/C(/[H])=C(/[H])C(=O)C(=O)OC([H])([H])C([H])([H])[H])\C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[H])[C@@]2([H])C([H])([H])C3=C([H])N(C4=C([H])C([H])=C([H])C(=C34)[C@@]2([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C(N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H]
[H]N1C(=O)N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])N(C4=C3C([H])=C(Cl)C([H])=C4[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2[C@@]([H])(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C3([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])N2C(=NC3=C([H])C4=C(C([H])=C3C2=O)C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]ON([H])C(=O)[C@@]([H])(O[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(Cl)=C([H])N2C1=NC(=C2C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=C([H])C([H])=C2N(C(=O)N([H])C([H])([H])C2=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(F)C([H])=C1F
[H]N(C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN(C([H])=N1)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
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[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C(=O)N(C1=C(C([H])=C([H])C([H])=C1[H])C(=O)O[H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(C(=O)OC([H])([H])[H])C(O[H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)C(=O)C([H])=C2C1=C([H])C(Cl)=C([H])C([H])=C1Cl
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=NSN=C1C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1Br)C([H])([H])C(=O)N([H])[H])C1=C(C2=C([H])C(=C([H])C([H])=C2N1[H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N
[H]N1N=NC(=N1)N1N=C(C2=C1OC(=O)C([H])=C2C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])N([H])C(=O)C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2O\C1=C(\[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])([H])C([H])([H])C([H])([H])O1
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])N(C2=C([H])C([H])=C([H])C(OC3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3[H])=C12)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C(F)=C1[H]
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[H]N([H])S(=O)(=O)\N=C(\N([H])C1=C([H])C2=C(OC(=C2[H])C([H])([H])[H])C([H])=C1[H])N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])O1
[H]O[C@@](C1=C([H])C([H])=C(OC2=C3C([H])=C(SC3=C([H])N=C2[H])C(=O)N([H])C([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])C(=O)C1=C([H])C([H])=C(OC2=C3C([H])=C(SC3=C([H])N=C2[H])C(=O)N([H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N(C(=O)C(N([H])C(=O)N2C([H])([H])C([H])([H])C([H])(N3C(=O)N([H])C4=C3C([H])=C([H])C([H])=N4)C([H])([H])C2([H])[H])=C1[H])C([H])([H])C(F)(F)F
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@@]3([H])[C@]4([H])C(=O)C([H])([H])[C@]5([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[C@]5(C([H])([H])[H])[C@@]4([H])C([H])([H])C(=O)[C@]23C([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(S1)S(=O)(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N1C(=O)C2=C([H])C([H])=C([H])C(N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])=C2C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)[C@@]([H])(N1C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
CCC1=C(C=CC=C1CCCC(O)=O)C1=CC=C(N=N1)C1=CC=C(OC(C)C)C(=C1)C#N
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(O1)S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[N+]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])([H])[C@]12C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])[C@@]2([H])C3=NC([H])=C(Br)C([H])=C3C([H])([H])C([H])([H])C3=C2C(Br)=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1(N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=NC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N([H])C(=S)N([H])\N=C(\C1=C([H])C(Br)=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(OC(=O)C([H])([H])[H])=C1[H]
[H]N(\N=C(\N([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]N([H])C1=C(Cl)C([H])=C(C(=O)OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C4=C3C([H])=C([H])C([H])=C4N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C2N([H])C3=C(C([H])=C([H])C(=C3[H])C3=C([H])N(N=C3[H])C([H])([H])[H])C2=C(N=C1[H])N([H])[C@@]([H])(C1([H])C([H])([H])C1([H])[H])C(F)(F)F
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[H]OC(=O)C([H])([H])[C@]([H])(C(=O)O[H])C1=C([H])C(C2=NC3=C([H])C(=C([H])C([H])=C3N2[H])C(=N[H])N([H])[H])=C(O[H])C([H])=C1[H]
[H]OC([H])([H])[C@]12C(=C([H])C([H])([H])[C@]3([H])[C@]4([H])C([H])([H])C([H])([H])C(=O)[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]13[H])[C@]([H])(O[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1(N([H])C(=O)C(F)(F)F)C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C(Cl)=C([H])C(Cl)=C1C1=NOC(=N1)C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)C1(C(=O)OC([H])([H])OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])S[C@@]([H])(C2=C([H])C([H])=C(C(=C2[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]OC1=NC2=C([H])C(Cl)=C(C([H])=C2C(OC([H])([H])C([H])([H])[C@@]2([H])N([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1C1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=NSN=C1[H]
[H]N=C(N([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])N([H])C1=C(Cl)C(=C([H])C(SC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C2N=C(C([H])=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N2N=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C(C#N)C(=N1)N([H])[H])[C@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C1=C3C([H])=C([H])C([H])=C([H])C3=C([H])C3=C([H])C([H])=C([H])C([H])=C13)C1=C([H])C([H])=C([H])C([H])=C1S2
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C(C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])C2=C([H])C([H])=C([H])C(F)=C2C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])C1=NC2=C([H])C([H])=C(F)C([H])=C2C(=C1[H])C(=O)OC([H])([H])[H]
[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C([H])=C3[H])C(=O)N([H])C1=O)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=C(C([H])=NC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C2=C(N([H])C([H])=NC1([H])[H])N(C([H])=N2)C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C(C2=C([H])C(=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C(F)(F)F
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=NC(=O)N([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(N([H])C(C2=C([H])C([H])=C(C([H])=C2[H])N2C(=NC3=C([H])N=C([H])C([H])=C23)C([H])([H])[H])=C(C(=O)OC([H])([H])C([H])([H])[H])[C@@]1([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
CCN1C(C)=C(C(=O)N(CC)C1=O)C1=CC=C(C[C@H](NC(=O)C2=C(Cl)C=CC=C2C)C(O)=O)C=C1
[H]C1=C([H])C([H])=C(S1)C(C(=O)O[C@@]1([H])C([H])([H])[N@+]2(C([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H])(C1=C([H])C([H])=C([H])S1)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(SC(Cl)=C2[H])N1[H])[C@@]1([H])C(=O)N([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])SC(=S)N(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H][C@@]1(CCCCN1CC#C)[C@H](C(=O)OC)C1=CC=CC=C1
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[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])S[H])[C@]([H])(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
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[H]N1C([H])=C([H])C2=C1C([H])=C([H])C(OS(=O)(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])=C2[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])(C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C(\[H])=C(/[H])C([H])([H])\N=C(\S[H])N([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=NN1C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])OC([H])([H])C1=C([H])C(I)=C([H])C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])N=C(N([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])=C12
[H]OC1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])=C3N(C4=C(C([H])=C([H])C([H])=C4[H])C3=C2[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]2([H])F)C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(=NN2C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(F)=C1[H])C1=C([H])C([H])=C([H])C(N([H])C2=C([H])C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=O)=C1[H]
NC(=O)C1=C(NC(=C1)C1=C(F)C=NC(N)=N1)C1=CC=CC=C1
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[H]N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C([H])([H])C([H])([H])[H]
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[H]N([H])C1=N[C@](C2=C([H])C([H])=C([H])C(F)=C12)(C1=C([H])C(=C(OC([H])([H])[H])C(=N1)C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=C([H])N=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2N1S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1F)N1C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])[C@]([H])(N([H])[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])N=C2C([H])=C1[H]
[H]C1=C([H])C(C2=NC(=C3N2C2=C([H])C(F)=C([H])C(OC([H])([H])[H])=C2N=C3C([H])([H])[H])C([H])([H])[H])=C(C([H])=N1)C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2N([H])C([H])=C([H])C2=C1C([H])([H])[H])C1=C(C#N)C([H])=NC([H])=C1\C([H])=C(/[H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1F)N(C([H])([H])C#C[H])C([H])([H])C1=C(C([H])=C2N=C(N=C(O[H])C2=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])S(=O)(=O)C(F)(F)F
[H]N(C(=O)C1=C(C(=NC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])N=C([H])C([H])=C1[H])[S@](=O)C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C2=NC(=NN12)C([H])([H])[H])C(=O)C([H])([H])C([H])([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC(=C([H])C([H])=C1[N+]([O-])=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])N2C(=O)C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C1=NN=C(O1)C([H])([H])[H])C1=C([H])C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(OC([H])([H])[C@]2(OC3=C([H])C([H])=C(C([H])=C3N(C([H])([H])[H])C2([H])[H])N(C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C([H])C(=C2C([H])=C1[H])[C@]1([H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(ON=C1C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])[C@]2([H])S[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=C([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=N1)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])N=C(OC([H])([H])C([H])([H])C(F)(F)F)C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H][C@]12SC=C(N1C(=O)\C2=C\C1=CN2C(SC3=C2C(C)=CC=C3)=N1)C(=O)O[Na]
[H]OC1=C([H])C(=C([H])C(O[H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
COC[C@H](C)OC1=CC(\C=C\C2=CC=CC=C2[N+]([O-])=O)=CC(=C1)C(=O)NC1=NN(C)C=C1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])OC2=C(C([H])=C(\C([H])=C(/[H])C3=C([H])C(O[H])=C([H])C(O[H])=C3[H])C([H])=C2[H])[C@]1([H])C1=C([H])C(O[H])=C([H])C(O[H])=C1[H]
[H]OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(C#N)=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H]
[H]OC1=C([H])C(Cl)=C([H])C([H])=C1C1=NC(N([H])C(=O)C2=C([H])C([H])=C([H])S2)=C(C#N)C(=C1[H])C1=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(C2=C([H])SC(=N2)C2=C([H])C([H])=NC([H])=C2[H])C(=O)N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C2=C(C([H])=C(C([H])=N2)C(=O)N([H])C2=NC(=C([H])S2)C2=C([H])C([H])=C([H])C(=C2F)C(F)(F)F)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C2=C1N=C(C([H])=C2[H])C([H])([H])[H])[C@]([H])(N([H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(S1)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C1([H])N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C2([H])N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])O[H])C([H])([H])SSC2([H])[H])C([H])([H])O[H])C([H])([H])O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)N([H])C([H])(C(=O)O[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)N([H])C1=NN=C(SC([H])([H])[H])S1
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC(=O)N([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])O[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])N([H])C2=O)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]C1=NC2=C(C([H])=C1Br)C([H])([H])C([H])([H])C1=C(C([H])=C([H])C(Cl)=C1[H])[C@@]2([H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(OC(=O)C([H])([H])C([H])([H])[H])C2=C3C(=C1[H])C([H])([H])[C@]1([H])[C@]4([H])C([H])=C([H])[C@]([H])(OS([O-])(=O)=O)[C@]([H])(O2)[C@]34C([H])([H])C([H])([H])[N@+]1([H])C([H])([H])[H]
[H]C([H])=C1C(=O)[C@]23C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]1(C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@](C(=O)OC([H])([H])[H])(C([H])([H])[H])[C@@]1([H])C([H])([H])[C@]3([H])OC(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(N2C(=O)N(C(=C(C2=O)C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])[H])C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2F)C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]\C(C(=O)C([H])([H])[H])=C1/SC2=C(C([H])=C(OC([H])([H])[H])C([H])=C2[H])N1C([H])([H])C([H])([H])[H]
[H]N([H])C1=N[C@]([H])(N2C(=N1)N([H])C1=C([H])C([H])=C([H])C([H])=C21)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C1=NC([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C([H])C2=C1C(=NS2)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3(SC2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
CN(C)CC1=CC=CC=C1SC1=C(CO)C=C([123I])C=C1
[H]OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C1=C([H])C(=NC2=C(C([H])=NN12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C1=C([H])C(OC([H])([H])C2([H])C([H])([H])C2([H])[H])=C(OC([H])(F)F)C([H])=C1[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C3OC(C4=C([H])C([H])=C([H])C([H])=C4[H])=C(C(=O)C3=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C(\[H])=C(/[H])C1=C(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C(N([H])C(=O)C2=C([H])C3=C(N2[H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]([H])(N([H])C1=C(C([H])=NC([H])=C1[H])S(=O)(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(N([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=NN(C2=C([H])C(Cl)=C(C#N)C([H])=C2[H])[C@]([H])(C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]1(C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@@]([H])(N([H])C([H])([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C(=O)N([H])[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C([H])C(F)=C2[H])C2=C1C(=C([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C3C([H])=C(OC4=C(C#N)C([H])=C([H])C(=C4[H])C([H])([H])N4C([H])=NC([H])=C4C([H])([H])N(C([H])([H])[H])[C@@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C([H])C3=C([H])C([H])=C2[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C(N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])SC([H])([H])C([H])([H])N1C(=O)C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C2C(=O)N(C3=C([H])C([H])=C(C([H])=C3[H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C2=C([H])C([H])=C1[H]
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[H]N(C(=O)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
COC(=O)C1=CC2=C(NC3=CC=C(OC(F)(F)F)C=C3)N=CN=C2S1
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[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]([H])(C1=NC([H])=C(N1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H]
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[H]N1N=NC([H])=C1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C(ON=C1C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C2=C1OC([H])([H])O2)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]N([H])C1=NC([H])=C(N=C1C(=O)N([H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C(F)=C1F
[H]N1C2=C(SC3=C2C([H])=C([H])C([H])=N3)C(=O)N(C1=O)C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
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[H]O[C@@]1([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2S[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])[H]
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[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N=C(N([H])[H])C1=C([H])N([H])C2=C1C([H])=C([H])C(=C2[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@]1([H])N([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
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[H]OC1=C2N(C3=C(C2=C([H])C(=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)[C@@]1([H])N([H])[C@]([H])(C([H])([H])C1([H])[H])C3([H])[H])C([H])([H])[H]
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[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])P(=O)(O[H])O[H]
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NS(=O)(=O)C1=C(F)C(F)=C(NC23CC4CC(CC(C4)C2)C3)C(F)=C1F
[H]OC(=O)C([H])([H])[C@@]([H])(O[H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[C@@]([H])(O[H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])([C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N1C([H])([H])[C@]([H])(OC([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])[C@]([H])(OC([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])OC(=O)N(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N(C1=NC([H])([H])C([H])([H])N([H])C(=C1[H])C1=C([H])C([H])=C(F)C([H])=C1F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C2N1C([H])([H])C1=C([H])C(OC3=C([H])C4=C(C([H])=C([H])C([H])=C4C([H])=C3[H])N3C(=O)C([H])([H])[N@](C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(=O)C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C#N
[H]N([H])N1C(SC([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)=NN=C1C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])(C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])\N=C(\S[H])N([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)[C@@]([H])(N(C([H])([H])C1=C([H])C2=C(N=C([H])N=C2N([H])C2=C(F)C(Cl)=C([H])C([H])=C2[H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C#N)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C([H])C(F)=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N2C(=O)N(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=NC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])N([H])[H]
[H]OC1=C(O[H])C(F)=C(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@@](C([H])([H])C1=C([H])C(=C([H])C(=C1C#N)C([H])([H])[H])C([H])([H])[H])(C([H])([H])C(C1=C([H])C(F)=C([H])C([H])=C1OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C([H])=C1F)[C@@]([H])(N(C1=NN(C(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1OC([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(Cl)C([H])=C(Cl)C([H])=C1S(=O)(=O)OC1=C(C([H])=C(Cl)C([H])=C1Cl)S(=O)(=O)N([H])C1=C([H])C([H])=C(SC2=NC3=C(S2)C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N1C2=C([H])C([H])=C(Cl)C([H])=C2C(=C1C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]1([H])OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@]1([H])N(C2=C([H])C([H])=NC(=N2)N2C([H])=NC([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C1SC(=C2[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])OC([H])=C1[H])C1=C(F)C([H])=C([H])C(N([H])C2=C([H])C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C3=O)=C1[H]
CC1=CC=C(C)C(=C1)N1CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1
[H]C1=C([H])C(=C([H])C([H])=C1C#N)C(=O)[C@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C([H])=C2N=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C2=C1[H]
[H]\C(=N/C1=C(C#N)C(=C(S1)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C#N
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=C(C([H])=O)C2=C1C([H])=C([H])C1=C2C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])C1(N(C(=O)C2=NOC(=C2[H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])N2N=C([H])N=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])=C([H])[H]
Cl[H].COC1=C(OC)C=C(C=C1)C(=O)OCCCCCN[C@H]1CCCC2=C1C=CC(=O)N2
[H]O\N=C1/C2=C(C([H])=C(C([H])=C2[H])C2=C([H])N(N=C2C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C([H])([H])O[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C1=C(C([H])=NC(=N1)N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(C([H])=C(Br)C([H])=C1Br)C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(C1=NC(=C([H])C2=NC([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1Br)C([H])([H])C(=O)OC([H])([H])[H])C1=C(C2=C([H])C(=C([H])C([H])=C2N1[H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(OC3=C([H])C([H])=C([H])C([H])=C3F)N(C3=NC([H])=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])N=C([H])C(=N1)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C2([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC2=C([H])C(O[H])=C([H])C([H])=C2C1=O)C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)C([H])([H])F)C([H])([H])C(=O)OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1(N([H])C(=O)C2(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(OC3=C(Cl)C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])N=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])SC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(\[H])=C(\[H])C1=C([H])C([H])=C([H])C(O[H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]C1=C(SC2=C1C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C21)C(=O)N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)[C@@]3([H])C([H])([H])[C@]3([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[C@@]1([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]2([H])N(C([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C([H])C([H])=C([H])C([H])=C3Cl)[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])[H]
[H]N(\N=C(/[H])C1=C([H])C(F)=C([H])C([H])=C1[H])C(=O)C1=C([H])SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])C2([H])[H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C(=O)N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(O1)C([H])([H])[H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])O[C@@]1([H])C([H])([H])C([H])([H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N([H])[C@@]([H])(C2([H])[H])[C@]1([H])C([H])([H])[H]
[H]OC1=C2N([H])C(=NC2=NC(=N1)N([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])[H]
[H]N1C([H])([H])C([H])([H])N2C3=C(C([H])=C(Cl)C([H])=C3C([H])([H])[C@@]2([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]\C(C(=O)C([H])([H])[H])=C1\SC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2N1C([H])([H])C([H])([H])[H]
[H]N1C(=NC([H])([H])C1([H])[H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N/C(=O)C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C(=O)\N=C(/N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])\N([H])[H]
[H]N(C1=C([H])C([H])=C2N([H])C([H])=C([H])C2=C1C([H])([H])[H])C1=C(C#N)C([H])=NC([H])=C1C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])[N+](=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C(=O)N([H])C(=S)N([H])C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])O1)C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)N(C2=C(C1=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]OC1=C([H])C([H])=C(C(O[H])=C1[H])[C@@]1([H])N([H])N=C(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C1([H])[H]
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[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3N([H])C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]1([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=NC([H])=C2C([H])([H])C(=O)C2=C([H])C([H])=C(F)C(=N2)C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N([H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])N1C(=C([H])C([H])=C1C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(O2)C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=NO2)C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C(=O)N1N=C(C2=C([H])C(Cl)=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]OC(=O)[C@]1([H])[C@@]([H])(C(=O)O[H])[C@@]([H])(C(=O)N(C([H])([H])C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C(=O)N(C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC2=C([H])C(=C([H])C([H])=C2S1)N1C([H])=C([H])C2=C(SC3=NC([H])=C([H])C(N(C([H])([H])[H])C([H])([H])[H])=C23)C1=O
[H]N(C([H])([H])C([H])([H])OC([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(Cl)=C([H])N(C1=O)[C@]([H])(C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C1=C(Cl)C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=NO1)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)S(=O)(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C1=C(C([H])=C(C([H])=C1[H])C(C1=C([H])C([H])=C(OC([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C([H])([H])[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N([H])[H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C(N=C1SC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C1=NN=NN1C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C([H])=C2N=C([H])C(=C([H])C2=C1C([H])([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC([H])=C(C([H])=C2C#N)C([H])([H])N2C([H])([H])C([H])([H])C2([H])[H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])N(C(=O)C2=C(N=NS2)C([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C2N(C3=C(C2=C([H])C(OC([H])([H])[H])=C1F)[C@]([H])(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])F
[H]N([H])C(=O)[C@@]1(C2=C([H])C([H])=C(C#N)C([H])=N2)C([H])([H])C2([H])N(C([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C(Cl)C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])N(C(=O)C2=C([H])C(Br)=C(Br)S2)C2=C([H])C([H])=C([H])C([H])=C12
[H]N(\C([H])=C1/N(C(=O)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2C1=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)C2=C3C4=C(C([H])=C([H])C([H])=C4[H])N4C3=C3N(C5=C(C([H])=C([H])C([H])=C5[H])C3=C2C1([H])[H])[C@@]1(O[C@@]4([H])C([H])([H])[C@]([H])(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])[C@]1([H])OC([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1(C([H])([H])N([H])S(=O)(=O)C(F)(F)F)C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C(Cl)=C(OC([H])([H])[H])C([H])=C2[H]
[H]N1C([H])=C(\C([H])=N\C2=NC(=C([H])S2)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2OC([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
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[H]OC1=NC([H])=C(Br)C([H])=C1C(=O)N([H])C1=C2N=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C2=C(OC1=O)C([H])=C([H])C(=C2[H])C([H])([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])S1)C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=N1)C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])F
[H]N([H])[C@](C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1F)C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]N(\N=C(\C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C(=S)SC([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1O[H])C1=C([H])C([H])=C(S1)C(\[H])=C1/SC(=O)N(C1=O)C([H])([H])C(=O)OC([H])([H])[H]
[H]ON([H])C(=O)[C@@](C([H])([H])[H])(C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])[C@@]2([H])N(C3=NN=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C1=NC2=C(SC(=C2[H])C2=NC([H])=C([H])S2)N2C1=NC([H])=C2C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=O)[C@@]2([H])C([H])=C([H])C(O[H])=C([H])[C@@]2([H])O1
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[H]N([H])C(=O)C([H])([H])N([H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
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[H]N(C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])=C(C#CC2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C(C2=C([H])C([H])=C([H])C([H])=C2Cl)C2=C([H])C(=C([H])C(=C2N=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2[C@@]([H])(N([H])C(=S)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H])[N+]([O-])=O
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=NN([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=NN([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H]
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[H]N([H])C1=NC(N(C(=N1)N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=NC2=C([H])C3=C(C([H])=C12)N(C(=O)N(C3=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1N=NC(=N1)[C@]([H])(OC([H])([H])C([H])([H])C1=C2S[C@]([H])(C([H])([H])[H])C([H])([H])C3=C2C(=C([H])C([H])=C3OC([H])([H])C2=C([H])C([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(N2N=C3C(=C2C([H])([H])[H])C(=NN=C3N2C([H])([H])C([H])(OC([H])([H])[H])C2([H])[H])C([H])([H])[H])=C(OC(F)(F)F)C([H])=C1Cl
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@](O[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]([H])(O[H])C([H])([H])[C@@]21C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[C@]1([H])C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)C2=C(N=C(N=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=C(N(C(=C1[H])C([H])([H])C([H])([H])C(=O)N(C1=C([H])C([H])=C(Cl)C(=C1Cl)C([H])([H])OC1=C2N=C(C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C(Cl)N=C1[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])[C@@]1([H])O[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=NC2=C(SC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)N=C([H])N=C2N1C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N([H])C1=C([H])C(C#CC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C2C(OC(=O)C(=C2C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])([N+]([H])([H])[H])[C@@]([H])(O[H])C([H])([H])C(\[H])=C(/[H])[C@@]([H])(O[H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=NC(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(O[H])C(Cl)=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C(I)C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(Cl)=C([H])N=C(N([H])C([H])([H])C(F)(F)C2=[N+]([O-])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C1=C([H])C(OC([H])(F)F)=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C(=C(Cl)C([H])=C1C([H])([H])[H])S(=O)(=O)N([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=NC(Cl)=NC(Cl)=N2)C([H])=C1[H]
[H]N([H])C([H])([H])[C@]1([H])O[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]3([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C4=C([H])C([H])=C(O[H])C([H])=C4[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)O[H]
[H]N(C1=NC([H])=NN2C([H])=C(C3=NN=C(O3)C([H])([H])C([H])([H])[H])C(=C12)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(N=C1[H])N([H])C(=C2[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@](N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]N(C(=O)C1=NC(=C([H])C([H])=C1[H])C1=C([H])C([H])=NN1[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C(=O)OC2=C([H])C(OC([H])([H])C3=C([H])C(Cl)=C([H])C([H])=C3[H])=C([H])C([H])=C12
[H]O[C@]([H])(C([H])([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(C(=O)N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])=C(C2=C1C([H])=C([H])C1=C2OC([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])C(F)(F)F
[H]OC1=C([H])C([H])=C(C2=NN(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C(O[H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C(C(=N1)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
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[H]C1=C([H])C(=C([H])C([H])=C1C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C(F)(F)F
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[H]C1=C([H])C(=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C2C(=O)C([H])([H])C(C2=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])OC([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])=C4C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@]4(C([H])=C([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(N=C2N1[H])C1=C([H])N([H])N=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H]
OC1=CC=CNC1=S
[H]OC1(C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(Br)=C([H])C([H])=C2OC([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C1=C([H])C(=C([H])C2=NC([H])=C(N=C12)N1C([H])([H])C([H])([H])C([H])(OC([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=NN=C2C([H])=C([H])C(=NN12)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=NC(=C([H])S1)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]N1[C@@]([H])(C([H])([H])[H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N(C(=O)C([H])([H])C2=C([H])C(=NO2)C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC([H])([H])C([H])([H])N2C([H])([H])[H])C([H])([H])C([H])([H])N(C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(Cl)C([H])=C2[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(C#N)=C2[H])[C@@]1([H])C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
CN(CC1=CC=CC=C1)C1=C2CCC(C)(C)CC2=C2C(SC3=C2N=CN=C3NCCN2CCOCC2)=N1
[H]O[C@@]1(C#C[H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])[C@@]4([H])C([H])([H])C5=C(C([H])=C(O5)S(=O)(=O)C([H])([H])[H])C([H])([H])[C@]4(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(=N[H])N([H])[H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1\C(SC2=C([H])C([H])=C([H])C([H])=C12)=C(/N=O)C#N
[H]N(\N=C(\C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C2C([H])=C([H])C(OC([H])([H])[H])=NN2N=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(N2C([H])=C([H])C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])S1)C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])S(=O)(=O)C1=C2C([H])=C([H])C([H])=C3C(=O)N(C(C([H])=C1[H])=C23)C([H])([H])C([H])([H])[H]
[H]N(N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C(=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])=C4C([H])([H])[C@@]5([H])OC([H])([H])C([H])([H])[C@@]4(C([H])([H])C5([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]N1C([H])=NC2=C1N=C(N1N=C(N=C21)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C(N=C(N1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1Cl
[H]OC(=O)[C@@]([H])(C([H])([H])C1=C([H])C(=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1F)C([H])([H])N([H])C(=O)C1=C(F)C([H])=C(C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])[H]
ClC1=CC=C(\C=N\NC2=NC3=CC=CC=C3N=C2CC2=CC=CC=C2)C=C1
[H]C1=C([H])C([H])=C(C#CC2=NC3=C(C([H])=C2[H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(C(=N1)C([H])([H])N1C([H])([H])C([H])([H])C2(C(=O)N(C3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
CC1=CC(Cl)=C(OCCOC2=CC=C(CC(CN)C3=C(C)C=C(C=C3)C3=CN=CN=C3)C=C2)C(Cl)=C1
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C(=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[18F]CCCN1CCC(COC2=CC=C(C=C2)C#N)CC1
[H]N(C(=O)C1=C([H])C([H])=C(O1)C([H])([H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC(N([H])C([H])([H])[C@@]2([H])OC([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=N1
CC1=CN=C(CNCC2(F)CCN(CC2)C(=O)C2=CC=CO2)C=C1
[H]OC([H])([H])[C@@]([H])(N([H])C(=O)[C@]1([H])C([H])=C2C3=C4C(N([H])C([H])=C4C([H])([H])[C@]2([H])N(C([H])([H])[H])C1([H])[H])=C([H])C([H])=C3[H])C([H])([H])[H]
CC(C)C[C@H](CO)NC1=NC(S[C@@H](C)C2=C(F)C=CC=C2)=NC2=C1SC(N)=N2
[H]N(C1=NC([H])=C(C2=NN=C(O2)C2([H])C([H])([H])C2([H])[H])C(OC([H])([H])C([H])([H])[H])=N1)C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(C2=C([H])C([H])=C([H])C(C#N)=C2[H])=C2N=C([H])C([H])=C([H])C2=C1[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])OC([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]C1=NC(=NC(=C1[H])N(C([H])([H])C1=C([H])C([H])=C(C#CC([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C#N
FC1=CC=CC=C1C(=O)N1CCN(CC2=CC=C(C=C2)C2=NN=C3N2C2=CC=CN=C2NC2=C3C=CC=C2)CC1
[H]OC1=C([H])C2=C(C(OC([H])([H])[H])=C(Cl)C(=C2[H])C([H])([H])[H])C2=C1C(=O)C1=C(O[H])C(=C(C([H])=C1C2=O)C(=O)OC([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C([H])C([H])=C(C([H])=C12)C1=C([H])C(=C2N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]([H])(C2=C1Cl)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C1=C([H])N=C2N=C(N=C(N([H])[H])C2=N1)N([H])[H])C([H])([H])C([H])([H])C(=O)O[H])C(=O)O[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]([H])(N([H])C(=O)OC([H])([H])[H])C1([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C(=S)N([H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C#N)C2=C(S1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
NC(=N)N1CCN(CCC2=CN(CC(=O)N[C@@H](C(O)=O)C3=CC=CC=C3)N=N2)CC1
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N1N=C([H])C(=C1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C(=O)OC([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N=C(S1)N1C([H])([H])C([H])([H])N(C(=O)[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C(=N1)C([H])([H])[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(N([H])[H])=C(C([H])=C1C([H])([H])[H])C(F)(F)F
[H]C1=NC(Cl)=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(=O)N=C(SC([H])([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2C(=O)OC([H])([H])[H])N1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]S\C(=N/C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C(ON=C1[H])C([H])([H])[H]
[H]C1=C(C2=C([H])C([H])=C([H])N=C2N1[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C(N([H])C([H])=N2)C(=N1)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])C1=C([H])C2=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C21
[H]N([H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C(=O)[C@@]([H])(N2C(=O)[C@@]([H])(N([H])C(=O)\C(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])[C@]([H])(OC(=O)[C@@]([H])(N([H])C1=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C(/[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N1C([H])=C(N=C1[C@]1([H])N([H])[C@@]2(C3=C(C4=C([H])C([H])=C([H])C([H])=C4N3[H])C1([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]C1=C([H])C2=C3C(=C([H])C([H])=C4C(=O)N(C(=O)C1=C34)C([H])([H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])[C@]([H])(C(=O)N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C([H])C(Br)=C([H])C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(N2C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C3=C([H])C([H])=C([H])C(C#N)=C3[H])C2([H])[H])=C(S1)C([H])([H])C([H])([H])[H]
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[H]N1C(=NC(=C1C1=C([H])C2=C(C([H])=C1[H])N(C(=O)N2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
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[H]OC([H])([H])C([H])([H])C([H])([H])N1C([H])=NC2=C(N=C(N=C12)C#N)N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@@]1([H])N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]12[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(N([H])[H])=[N+]([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N1C(=O)C(=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]C1=NN(C2=C1C([H])([H])SC1=C(SC(=C21)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=NC(=O)N=C12)C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[C@@]2([H])SC(=O)N([H])C2=O)C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@]([H])(C(=O)N(C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)C(=O)OC([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])\C(=C(\[H])C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C(F)C([H])=C12
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(O[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(Cl)=C2[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=NC([H])=C([H])C(OC2=C([H])C3=C(OC(=N3)N([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])=C1[H])C([H])([H])[H]
[H]N(C1=NC([H])=C2C([H])=C([H])N(C2=N1)C1=C([H])C([H])=C([H])C([H])=N1)C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@]([H])(O[P@@](=O)(O[H])O[P@](=O)(O[H])O[P@](=O)(O[H])O[P@](=O)(O[H])OC([H])([H])[C@@]2([H])O[C@@]([H])(N3C([H])=C([H])C(=O)N([H])C3=O)[C@]([H])(O[H])[C@]2([H])O[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@@]1([H])O[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])=NC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12
[H]OC1=C([H])C([H])=C(N([H])C2=NC(=C([H])S2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])N2[C@]1([H])C(=O)N(C1=C(C(Cl)=C(C#N)C([H])=C1[H])C([H])([H])[H])S2(=O)=O
[H]N(C(=O)C1=NOC(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]2([H])OC(=O)[C@@]3([H])N(C(=O)C(=O)[C@]4(O[H])O[C@@]([H])(C([H])([H])C([H])([H])[C@@]4([H])C([H])([H])[H])C([H])([H])[C@]([H])(C4=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C4OC([H])([H])[H])\C(=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C([H])\[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)[C@]([H])(OC([H])([H])[H])[C@]([H])(O[H])\C(=C([H])\[C@]([H])(C(=O)C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(S1)C([H])([H])[H])C1=C([H])C([H])=C([H])C(N([H])C2=C([H])C([H])=C3C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4C3=O)=C2[H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@]13C([H])([H])C([H])([H])N(C([H])([H])C4([H])C([H])([H])C([H])([H])C4([H])[H])[C@]([H])(C2([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H]
BrC1=C2NC(=O)OC2=CC(C[C@@H](NC(=O)N2CCC(CC2)N2CC3=C(NC2=O)C=CC=C3)C(=O)N2CCC(CC2)N2CCCCC2)=C1
[H]N1N=C(C(=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=S)S1)C([H])([H])C([H])([H])C#N
[H]N1C(=NC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[C@]([H])(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(F)=C1[H])C([H])([H])[H]
[H]N=C(N(C([H])([H])[H])C([H])([H])[H])C1=C([H])SC(=C1[H])C(=O)N([H])C1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=N1
CN1C=C(C=N1)C1=CC2=C(C=CC3=C(C=C(CS(=O)(=O)NCC4=NN=CC=C4)C=C3)C2=O)N=C1
[H]N(C(=O)C(F)(F)F)[C@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NSC4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])N1N=C([H])N=C1[H])C(C#N)(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N2C(=NC(=C2C2=NN(C(=O)C([H])=C2[H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=C(F)C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=NC([H])=C(C([H])=C2N1S(=O)(=O)C1=C([H])C([H])=C([H])C2=NON=C12)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C(=C(C([H])=C2N=C(C2=C([H])C([H])=C([H])C(=C2[H])C2=C([H])C(=NC([H])=C2[H])C([H])([H])OC([H])([H])[H])C([H])([H])C1=O)C([H])([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])[C@@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@](C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])(C([H])([H])F)C([H])([H])F)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)(C([H])([H])[H])C(F)(F)F
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=NC(=C(C([H])=C1[H])[C@@]([H])(C#N)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])ON=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C([H])=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N1C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]2([H])N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(F)(F)F
[H]OC1=C([H])OC(=C([H])C1=O)C([H])([H])SC([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])[N@@+](C([H])([H])[H])(C([H])([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C2=NC(=NC([H])=C2[N+]([O-])=O)N([H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2F)C([H])([H])C1([H])[H]
[H]N1C(=O)N(C([H])([H])[H])[C@]2(C1=O)C([H])([H])C1=C(C([H])=C3N=C(OC3=C1[H])C([H])([H])N1C(=O)N(C3=C1C([H])=C([H])C([H])=C3[H])C1=C([H])C([H])=C([H])C([H])=N1)C2([H])[H]
[H]N(C1=NC([H])([H])C2=C1C([H])([H])N(C(=O)O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C1=C(F)C([H])=NC([H])=N1
[H]N(C(=O)N1C([H])([H])C([H])([H])N(\C(=N\C#N)N([H])C2=C3C([H])=C([H])N([H])C3=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(Br)C([H])=C2[H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C(Cl)C([H])=C(C(=O)N([H])[C@@]2([H])[C@@]3([H])C([H])([H])N4C([H])([H])[C@]2([H])C([H])([H])[C@@]4([H])C3([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N2C(=NC([H])=C2C2=C([H])N([H])N=C2[H])C([H])=N1
[H]C1=C(N(N=C1OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])C2=C(C3=C([H])C(F)=C([H])C(=C3N2[C@]([H])(C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[S@](=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]OC1=C(OC([H])([H])[H])C([H])=C([H])C2=C1[C@]13C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]([H])(C2([H])[H])[C@@]11C([H])([H])\C(=C(/C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])[C@]3([H])C(=O)C([H])([H])C1([H])[H]
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[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C3=NSN=C3C([H])=C1[H])C([H])([H])C2([H])[H]
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[H]N([H])C(=O)C([H])([H])C([H])([H])N1C(=O)C(=NC2=C([H])C([H])=C(N=C12)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C(C(=O)N(C1=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C(=O)N([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N(C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1N=C(N(\N=C(/[H])C2=C([H])C([H])=C([H])N2C([H])([H])[H])C1=S)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C2N=C([H])C([H])=C([H])C2=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])OC([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]OC(=O)[C@@]1([H])N([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C3C(=C2[H])C(=O)C2=C3C([H])=C([H])C([H])=C2[H])[C@@]1([H])C(=O)O[H]
[H]C1=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])\N=C1\SN(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=NC([H])=C([H])S1)[C@@]([H])(C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])N=C([H])S1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]N(N1C(=O)N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
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[H]N1C(=O)N(C2=C(C(=NC(=N2)N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=C2C([H])([H])[H])C([H])([H])N1C([H])=NC([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
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[H]C([H])=C([H])C([H])([H])N1C([H])([H])C([H])([H])N(\C(=N/C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(O[H])C([H])([H])[C@@]([H])(O[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])C([H])([H])SC1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
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[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C(=O)C2=C(N(C3=C([H])C(=C([H])C([H])=C23)C([H])([H])[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])OC([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])[C@@]([H])(C([H])=C2C3=C([H])C([H])=C([H])C4=C3C(=C([H])N4C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])[C@@]12[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=NC(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3F)=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])N1C([H])=NC([H])=C1[H]
[H]OC(=O)[C@]([H])(SC1=NC(N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C(Cl)=N1)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]O[C@]1([H])[C@]([H])(O[C@]([H])(C([H])([H])OP([O-])(=O)OP([O-])(=O)O[H])[C@@]1([H])O[H])N1C([H])=C([H])C(=O)N([H])C1=O
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])S(=O)(=O)C([H])([H])C(F)(F)F)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(Cl)=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])SC([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])F)C([H])([H])C1([H])[H]
[H]N1N=NC([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C(OC2=C([H])C(Cl)=C(Cl)C([H])=C2[H])=NC([H])=C1C(F)(F)F
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=N1)C1=C([H])C(F)=C([H])C(F)=C1[H])C1=C([H])C(=NN1C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)[C@@]1([H])[C@]2([H])C([H])([H])N(C3=C([H])C([H])=C(C([H])=C3[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[C@]12[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C(=O)C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])N=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(C([H])=O)N(C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C(SC([H])([H])C([H])([H])C4([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])N=C23)N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])[C@]([H])(O[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
OC1=CC(O)=C(C=C1)C1=NN=C(S1)C1=CC(O)=C(O)C=C1
[H]C1=C([H])N(C([H])=N1)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(C#N)=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C3=NSN=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1[C@]2([H])C3=C([H])C([H])=C([H])C([H])=C3[C@]1(C1=C(C([H])=C([H])C([H])=C1[H])C2([H])[H])C([H])([H])Cl
[H]OC1=C(OC([H])([H])[H])C(C(=O)N([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])=C(C(Cl)=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[P+](C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[P+](C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
ClCC1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
[H]OC(=O)C([H])([H])[C@@]([H])(C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])SC(=N1)C([H])([H])C([H])([H])C([H])([H])C1=NC2=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N2[H]
[H]ON(C([H])=O)[C@]([H])([C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=NC([H])=C([H])S1)C([H])([H])C([H])([H])C([H])([H])\N=C(\N([H])[H])N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])C([H])([H])C([H])([H])O[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])N=C(N1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]ON(C(=O)C([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C2([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])O[C@@]([H])(OC([H])([H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])[C@]([H])(OC([H])([H])C2=C([H])N([H])C([H])=N2)[C@@]([H])(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]1([H])OC([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]O\N=C(/C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)N1C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])N(C(=C1[H])C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C([H])C([H])=C(C([H])=C3C([H])([H])C2([H])[H])C2=NOC(=C2[H])C([H])([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]ON(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C1=C([H])C2=C(OC(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]OP(=O)(O[H])OC([H])([H])[C@](N([H])[H])(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=NC(=N1)N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C(=C([H])C(C#N)=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])P(=O)(OC1=C([H])C([H])=C([H])C([H])=C1[H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(Br)O1)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]OC1=C(OC([H])([H])[H])C([H])=C2C([H])=C([H])N=C3C4=C(C([H])=C([H])C([H])=C4[H])C(=O)C1=C23
[H]OC1=C2C(=NC(=N1)N([H])[H])N([H])C(=C2SC1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])[C@@](N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])(C(=O)OC([H])([H])C([H])([H])[H])C(F)(F)F
[H]N(C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N1C(=NN=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1N=C([H])C2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C([H])N=C12)C(=O)C1=NC([H])=C([H])S1
O[As](O)(=O)C1=CC=CC=C1
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])[N+]([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(SC2([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(C(OC([H])([H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]2([H])C3=C(C([H])=C([H])C([H])=N3)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]OC1(C([H])([H])C([H])([H])C([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(C(=O)C2=C([H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C3=C([H])C(Br)=C([H])C([H])=C23)=C2N1[C@@]([H])(SC2([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C(=O)N(C([H])=C2[H])C([H])([H])[H])[C@@]([H])(C(=O)N(C([H])([H])C2=C([H])N(C3=C2C(F)=C([H])C([H])=C3[H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C2([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C1=NC(=NN(C1=O)[C@]([H])(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=C(C([H])=C1Cl)C(F)(F)F
[H]N1C2=C(N=C1[C@@]1([H])N(C(=O)C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])(C4=NC(=NO4)C4=C([H])C([H])=C(C([H])=C4[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])=C(Cl)C(Cl)=C2[H]
[H]N(C(=O)C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC2=C([H])N=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])N1C(=C(C(=C1C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=NC2=C(S1)C([H])=C(C([H])=C2[H])C1=C([H])C([H])=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(\C([H])=C(/[H])C2=NC3=C(N2C([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=NC(=N1)C([H])([H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C2=C(C([H])=N1)C(=O)C(=C([H])N2C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C(F)(F)F
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1(N2C([H])([H])C([H])([H])C([H])(F)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CC1=NN=C2CCC3=C(C=CC(=C3)C3=CN=CC4=CC=CC=C34)N12
[H]N(C(=O)C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])SSC([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(C2=NC(=C3N2C([H])=C([H])N=C3N([H])[H])C2=C(C([H])=C(C([H])=C2[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
COC1=CC=C(OC2=C(Cl)C=NN(C(C(=O)C3=CC=CC=C3)C3=CC=CC=C3)C2=O)C=C1
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C(N([H])[H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=C(N([H])C(=O)N([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])C([H])([H])N(C3=C(OC(F)(F)F)C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C#N
[H]OP(=O)(O[H])C([H])(C([H])([H])N1C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])P(=O)(O[H])O[H]
[H]N([C@]1([H])C([H])([H])C([H])([H])[C@](C(=O)N2C([H])([H])C([H])([H])N(C3=NN=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]1([H])[C@@]2([H])C([H])([H])OC([H])([H])[C@]1([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C(O[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=C(OC2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])N=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C(=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=NC2=C(S1)C([H])=C([H])C(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C2[H]
[H]C1=C([H])C2=C(C3=C([H])C4=C(OC([H])([H])O4)C([H])=C13)[N+](=C([H])C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C21)C([H])([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C(O2)C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C#CC([H])([H])N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])[S@](=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])C([H])([H])C1=C(C2=C(N=C(N=C2N=C1[H])N([H])[H])N([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N([H])C(=O)C1=C([H])C2=C(N=C(C([H])=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])[C@]3([H])OC4=C5C([H])=C([H])C(=NC5=C([H])C([H])=C4OC3([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])OC(=O)C1=C([H])C(O[H])=C(C(O[H])=C1[H])[C@]1([H])OC(=O)C2=C1C(O[H])=C([H])C([H])=C2[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2[C@@]2(C1=O)[C@]([H])(C(=O)C1=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C1[H])[C@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])[C@@]21C(=O)N([H])C2=C1C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C(ON=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])([H])[C@@]2([H])C([H])([H])[C@]1([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N(C1=NC([H])=NC(N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H])C1=C(Cl)C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1Cl
[H]C1=C([H])N(C([H])=N1)C([H])([H])[C@@]1([H])SC2=C(C([H])=C(F)C([H])=C2[H])[C@@]1([H])OC([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1F
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C(N=C1[H])C#N
[H]\C(=C1/C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(OC([H])([H])C2([H])[H])C([H])=C1[H])C1=NN=C(S1)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C(OC2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C(OC([H])([H])C([H])([H])N([H])S(=O)(=O)C([H])([H])C([H])([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=NC([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])[C@]2([H])C([H])([H])[C@@]1([H])C([H])([H])[C@@]2([H])N([H])C1=C2N=C(N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])N(C2=NC([H])=N1)C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C1=NC2=C(S1)C([H])([H])N(C([H])([H])C2([H])[H])[C@@]([H])(C1=C([H])N=C(N([H])C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=S)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1C(F)(F)F
[H]N1C(=O)N(C(=O)[C@@]1(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(SC(=C2C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])[H])=NC([H])=N1
[H]C1=C([H])C([H])=C(C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)N([H])[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C(C(=O)OC([H])([H])[H])=C1C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(N1C([H])([H])[C@]([H])(N(C([H])([H])C([H])=C([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C(=O)N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])[C@@]([H])(C([H])([H])OC([H])([H])C2=C([H])C(=C(F)C([H])=C2[H])C(F)(F)F)C1([H])[H]
[H]C1=C([H])C([H])=C2N=C(C3=C(N=C(N3C2=N1)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(OC2([H])C([H])([H])N(C3=NC4=C(S3)C([H])=C([H])C([H])=C4[H])C2([H])[H])=C(C([H])=C1[H])C1=C([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)OC([H])([H])[H]
[H]C1=C(C(OC2=C([H])C([H])=C(C#N)C([H])=C2[H])=C(N1C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(N(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C2C(=O)C3=C(N([H])N=C3C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])S1
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[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])[H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C2([H])[H]
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[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C2=C(N([H])C(=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2F)C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])OC1=C([H])C(Cl)=C([H])C([H])=C1[H])C1([H])C([H])([H])N(C([H])([H])C2=C([H])N(C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C1([H])[H]
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[H]N(\N=C1/C(=O)N([H])N=C1C1=C([H])N=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(N=C(S1)N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)[C@@]2([H])N(C(=O)C([H])([H])C3([H])C4=C(C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C#CC1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C(C([H])=C([H])N=C12)C1=C(N=C(N1C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=NC(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C(Cl)=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])C([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C([H])=C([H])C(Cl)=C2[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1\C(S\C(=C(/[H])C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1=O)=N\C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=NC([H])=C2C([H])=C1[H])[C@@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(N([H])C(=O)C3=NN=C(O3)N([H])C3=C(F)C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]ON(\C([H])=C(\[H])C(=O)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]O[C@]([H])(C([H])([H])OC1=C2C(N([H])C(=O)C22C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC2=NC([H])=C(C([H])=C2[H])C(=O)N([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F)C([H])([H])C(F)(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C#N)C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
CCCCCC1=CC=CC=C1C1=CC=C(OC(CC2=CC=CC=C2)C(O)=O)C=C1
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[H]N(C(=O)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C1C([H])=C(OC([H])([H])[H])C(Cl)=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])O[N+]([O-])=O
[H]N(C(=O)C1=C([H])C(=C([H])N1[H])C1=NN([H])C([H])=C1C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
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[H]C1=C([H])C([H])=C(O1)[C@]1([H])N(N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C([H])([H])[H]
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[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2C2=NN(C([H])=C12)C1=C([H])C([H])=C(F)C([H])=C1[H]
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[H]N1C([H])([H])C([H])([H])N(C2=C(C#N)C3=C(N2C([H])([H])C#CC([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])C2=NC([H])=C3C([H])=C([H])C([H])=C([H])C3=C2C#N)C([H])([H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(=O)N(C2=O)C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])=C1[H]
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[H]C1=C([H])C(=C([H])C(F)=C1F)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C([H])C4=C(N=C(O4)C([H])([H])C([H])([H])[H])C([H])=C3C([H])([H])C2([H])[H])N1C([H])([H])[H]
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[H]N(C(=O)O[C@]1([H])C(=O)N(C(=O)OC2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C(N2[H])C2=NN([H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])[H]