[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C3=C([H])C(=NC(=N3)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C2N([H])C([H])([H])C3=C(OC2=NC([H])=N1)C([H])=C(OC([H])([H])[H])C([H])=C3[H])C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])N=C(SC([H])([H])[H])N=C1N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C2OC([H])([H])C([H])([H])C2=C([H])C(Cl)=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])=C(C2=C([H])C(F)=C([H])C([H])=C12)C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C(N=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N1C([H])([H])[C@@]2([H])C([H])=C([H])S[C@@]2([H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N1C(=O)C(C2=C([H])N(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[H])=C(C1=O)C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(N=C1[H])C([H])=C(C([H])=C2[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]N([H])C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=C([H])N=C([H])C(=N1)N([H])[C@]([H])(C1=NC([H])=C(F)C([H])=N1)C([H])([H])[H]
[H]N([H])C1=NN2C([H])=C([H])C([H])=NC2=C1C1=NC([H])=NC(=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(F)(F)F)C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C(N([H])C(=O)C2=NC3=C(S2)C([H])([H])N(C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]N(C1=C([H])C([H])=C2N=NN(C2=N1)C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=S)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC1=C([H])C(Cl)=C([H])C([H])=C1C1=NC(N([H])C(=O)C2=C([H])C([H])=C([H])S2)=C(C#N)C(=C1[H])C1=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N([H])[H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])C([H])=C([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1(O[H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N=[N+]=[N-])C([H])=C2[H])C1([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(N2N=C(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(Cl)=C2C([H])([H])[H])C(=C1[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC(OC2=C([H])C([H])=C([H])C([H])=C2[H])=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1
CC1=CC2=C(OC=C3C=[N+](C4=CC=C(C=C4)S(N)(=O)=O)[Zn]4(Cl)(Cl)(OC5C(=COC6=CC=C(C)C=C56)C=[N+]4C4=CC=C(C=C4)S(N)(=O)=O)OC23)C=C1
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])N2N=C([H])C(=C2C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])C2=C([H])C3=C([H])C([H])=C([H])N=C3C([H])=C2[H])=C1[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])S[C@]([H])(C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=NC2=C([H])C(Cl)=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([O-])=O
[H]N(C(=O)C1=C([H])C(=O)C2=C(O1)C(=C([H])C(F)=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2N=C(N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
CC(=O)N1CCC(CN2C(N)=NC3(CC(C)(C)OC4=C3C=C(C=C4)C3=CC(Cl)=CC=C3)C2=O)CC1
[H]N(N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C([H])=C1C([H])([H])[H])C1=NC([H])=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N2C([H])=C([H])C([H])=C2C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])N([C@]([H])(C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C3=C([H])C4=C(OC([H])([H])O4)C([H])=C3[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(OC2=C(N([H])C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3S(=O)(=O)N([H])[H])C([H])=C([H])C(=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=NN(C2=NC(=O)N(C(=O)C2=N1)C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C(OC2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(OC([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])=NC([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C(C([H])=C([H])O1)C([H])([H])N(C([H])([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C2=NC([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
CC1=CN=C(CNCC2(F)CCN(CC2)C(=O)C2=CC=C(Br)S2)C=C1
[H]OC([H])([H])[C@@]([H])(O[H])C([H])([H])ON1C([H])=NC2=C(C1=O)C(N([H])C1=C([H])C([H])=C(I)C([H])=C1F)=C(F)C(=O)N2C([H])([H])[H]
C[C@H]1C2CC3=CC=C(C=C3[C@@]1(C)CCN2CC1CC1)C(=O)NCCC1=CC=C(N=C1)C1=CC=CC=C1
[H]N1C([H])=C(C2=C([H])C(=C([H])C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])S1(=O)=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(SC2=C1C([H])=C1C(=O)C([H])([H])C([H])([H])C([H])([H])C1=N2)C(=O)N([H])C1=NC([H])=C([H])S1
[H]N([H])C1=NN([H])C2=C1C(=C([H])C([H])=C2F)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(SC([H])([H])[C@]2([H])O[C@@](OC2([H])[H])(C([H])([H])N2C([H])=NC([H])=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(Cl)C([H])=C2C(=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C(N3N=C(C(=C3N=C2C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=O)C2=C(O1)C(=C(O[H])C([H])=C2O[H])C1=C(OC2=C([H])C(O[H])=C([H])C(O[H])=C2C1=O)C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C(Cl)C([H])=C(Cl)C([H])=C3[H])C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C2=C([H])C(C#N)=C([H])C([H])=C2O[C@@]1([H])C(F)(F)F
CN(CC(=O)N[C@@H](CCC\N=C/N)B(O)O)C(=O)CCC1=CC=CC=C1
[H]C1=C([H])C([H])=C2C(=C([H])C([H])=C(\N=C3/OC([H])([H])C4(C([H])([H])N3C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C2=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C2=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N2C(Br)=C(N=C2C(OC([H])([H])C2=C(Cl)C([H])=C([H])C(OC([H])([H])[H])=C2Cl)=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(=O)N=C(SC([H])([H])C(=O)N([H])C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)N1C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN2C3=C(C([H])=C([H])C([H])=C3[H])C3=C2C(=N1)C([H])=C(N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C3=O
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(O[C@@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])C([H])([H])C1=C([H])C([H])=C(N=C=S)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(N([H])C(=O)C2=C(O[H])C3=C([H])C(=C([H])C([H])=C3N=C2O[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C1=NC2=C(S1)C([H])([H])N(C(=O)C([H])([H])C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)[N+]([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(Br)C([H])=C2[H])C1=O)C(=O)O[H]
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[H]N(C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]N(C(=O)C([H])([H])SC1=NC([H])=NN1[H])C1=C(C#N)C2=C(S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@]1([H])C([H])([H])O[C@]([H])(O[C@@]1([H])C1=C([H])N=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H]
[H]C1=NC([H])=C(C([H])=C1[H])[C@]([H])(C(=O)O[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])[C@@]([H])([C@]1([H])C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C(OC(F)(F)F)=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(C#N)(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C1=C(C([H])=C2[H])C(=O)N([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1(F)[C@]2([H])C([H])([H])[C@@]([H])(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@@](N([H])[H])(C(=O)O[H])[C@]12[H]
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C(F)(F)F)C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1(C#N)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(N([H])[H])C([H])=C2[H])C([H])([H])SSC([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])[C@]([H])(O[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C(C(N([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C2N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(O1)C(\[H])=C1/SC(=S)N(C1=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(C([H])([H])S[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])N(C1=NC([H])=NC2=C1C([H])=C(C([H])=C2[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
CC(C)C[C@H](CO)NC1=NC(SCC2=CC=C(C=C2)C#N)=NC2=C1SC(N)=N2
[H]N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(N(C([H])([H])[H])C([H])([H])[H])=C(C#N)C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=N1)C(=O)N([H])C([H])([H])C([H])([H])C(=O)N([H])C1=NN=C(S1)S(=O)(=O)N([H])[H]
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C[C@@H](NC(=O)C1=CC(=CC(=C1)N(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)[C@H](O)CNCCC1CCN(CC2=CC=CC=C2)CC1)C1=CC=C(F)C=C1
[H]N([H])C1=NC(=C([H])C([H])=C1[H])C1=NC(=NC(N([H])C(=O)C([H])([H])[H])=C1[H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
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[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N([H])C1=C(F)C(F)=C(F)C(F)=C1F)C(\[H])=C1/C([H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]N1C(=O)N(C2=C(C(=C([H])C(=C2[H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]C1=C([H])C(F)=C(C([H])=C1[H])[C@]1([H])OC2=C(N=NC(SC([H])([H])[H])=N2)C2=C(C([H])=C([H])C([H])=C2[H])N1C(=O)C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=NC2=C(S1)C(O[H])=C([H])C(O[H])=C2[H]
[H]N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N([H])C1=C([H])C([H])=C2N(C(=O)N=C(C3=C([H])C([H])=C(C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C2N(C([H])([H])[H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3(C2=C1[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2N=C(I)C3=C(N=C([H])N=C23)N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=NN(C([H])=C3C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])[H])C1(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C2=O)C([H])([H])C1([H])[H]
[H]C1=C([H])C(F)=C([H])C(=C1[H])C1=NC(=C(O1)C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C2C(OC(=O)[C@@]([H])(C(=O)OC([H])([H])[H])C2([H])[H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C2=C([H])C(Cl)=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C(Cl)C2=C([H])C([H])=C([H])C([H])=C2S1)C1=C([H])C([H])=C([H])C(=C1[H])C1=NC2=C(O1)C([H])=C([H])C([H])=N2
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])P(=O)(O[H])O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(C([H])=C([H])C([H])=N1)C(=O)C1=NC(=C([H])C([H])=C1[H])N1C([H])([H])C([H])(C([H])([H])N([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=O)N(C([H])([H])[H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(SC([H])([H])C([H])([H])C([H])([H])[H])=N1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1\C(=N/C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])N(C2=C([H])C(Cl)=C([H])C([H])=C12)C([H])([H])[H])C1=NN=NN1[H]
[H]C1=C(SC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=N[C@]([H])(C2=C([H])C([H])=C([H])O2)C([H])([H])C2=C1SC([H])=C2[H]
[H]N(C(=O)C1=C([H])C(N([H])C(=O)C2=NC([H])=C(N=C2[H])C([H])([H])[H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])C2=C([H])N(N=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=NC([H])=C([H])S1
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]12C3=C(N([H])C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C2([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N2C(=NN=C2C(F)(F)F)[C@]1([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(\C([H])=C(/[H])C2=C([H])C([H])=NC([H])=C2[H])=C([H])N=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])N(OC([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(Br)C(OC([H])([H])[H])=C1C(=O)N([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]([H])(C(=O)O[C@@]1([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[N@+]2(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=NC2=C1N=C(OC([H])([H])[H])N=C2[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N(C(=O)C1=C([H])C(C#N)=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C(=NN1C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@]1(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C3(O[H])C([H])([H])C3([H])[H])[C@]([H])(C2([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])[H])C([H])([H])[C@]1(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2([H])N(C([H])(C3=C(Cl)C([H])=C([H])C([H])=C3[H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])[C@@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C(C2=NSN=C2OC([H])([H])C([H])([H])C#CC([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@]([H])(O[C@]1([H])C([H])([H])OP(=O)(O[H])O[H])N1C([H])=C(C(=O)N([H])C1=O)C1=C([H])C(OC([H])([H])[H])=C(C(=C1OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=C(C([H])=N1)C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C([H])=C(C([H])([H])[H])C([H])([H])N1C([H])([H])[C@@]([H])(N(C([H])([H])[C@@]1([H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=C3C(N([H])C([H])=C3C([H])([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])=C([H])C(=C2[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])[C@]([H])(OC(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)[C@@]2([H])C([H])([H])C([H])=C([H])C([H])([H])[C@@]2([H])C1=O)C1=NC([H])=C([H])S1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N(N1C2=C([H])C([H])=C(Cl)C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C(S1)C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N1C([H])=NC([H])=C1[H])C2([H])[H]
[H]N=C(N([H])C1=C([H])C2=C(C([H])=C1[H])N(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]N(C(=O)O[C@]([H])(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])N([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2O1
COC(=O)C(N1C(C2=CC=C(Cl)C=C2)C(=S)NC2=CC(F)=CC=C2C1=O)C1=CC=C(Cl)C=C1
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C1=NC([H])=C(O1)C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C([H])=C1C1=C2C([H])=NN([H])C2=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C([H])=NN2[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C(=O)N2C3=C(N([H])C(=O)C4=C2C([H])=C([H])C([H])=C4[H])C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])OC2=C([H])C([H])=C(C([H])=C2OC1([H])[H])C([H])([H])N([H])C(=O)[C@@]1([H])SC([H])([H])C([H])([H])N1C(=O)C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1F
[H]OC(=O)C1=C([H])C2=C([H])C([H])([H])[C@]3([H])[C@]4([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)C5=C([H])C([H])=C([H])C([H])=C5[H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])\C(=N\C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])\N=C1/N3C(=NC4=C1C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])N1C(=N2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C2=C1C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])[C@]2([H])C([H])([H])N(C(=O)C3=C(N=C([H])N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])=C(C(=NC1=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])N([H])C2=NC3=C(N2[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(Br)C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C(=C2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC1=NC2=C(S1)C([H])=C(N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])=C2[H]
[H]OC1=C(C([H])=C(OC([H])([H])[H])C(Br)=C1[H])C([H])([H])[C@@]1([H])C(=C([H])[H])C([H])=C(C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]OP(=O)(O[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N([H])C(=O)C([H])([H])[C@@]([H])(C([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2(N([H])C(=O)C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C(=O)N([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(F)C([H])=C(C([H])=C1[H])[C@@]1(O[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])F)[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(N([H])C(=O)C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])=C2[H])N(C2=C([H])C3=C(C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(C3=C(O2)C([H])=C([H])C([H])=C3C#N)C([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(O[C@@]([H])(C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C(F)C([H])=C3[H])[C@]2([H])C1([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C([H])([H])[H])[C@]2(C1=O)C([H])([H])C1=C(C([H])=C3C([H])=C([H])C(=NC3=C1[H])C([H])([H])N1C3=C4C(N([H])C(=O)C([H])([H])[C@]4([H])C1([H])[H])=C([H])C([H])=C3[H])C2([H])[H]
[H]N(C(=O)C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N1C(Br)=C2C3=C(C([H])=C([H])C([H])=C13)[C@@]1([H])C([H])([H])[C@@]([H])(C(=O)N3C([H])([H])C([H])([H])N(C4=C([H])C5=NON=C5C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C2([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C(C([H])=C([H])C([H])=C12)C([H])([H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C11C([H])([H])C([H])([H])N(C2=NC3=C(O2)C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])OC(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F)C(=O)N([H])C([H])([H])C(=O)N([H])[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])S(=O)(=O)C1=C([H])C([H])=C(N=C=S)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C2OC3=C(OC(=O)C2=C1OC([H])([H])[H])C([H])=C(C([H])=C3OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C#N)C2=C(C([H])=C(N=C2N1C1=C([H])C([H])=C(C([H])=C1Br)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2N=C1[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]2(OC3=C([H])C([H])=C4N([H])N=C([H])C4=C3C([H])([H])C2([H])[H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C(=O)N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])SC(=O)N([H])C1=O
COC1=CC=CC=C1CNC1=NC(NC2CCCC2)=C(C=N1)C(=O)NCCNC(C)=O
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]OC(=O)[C@@]1([H])C([H])([H])C2=C(SC(=C2[H])C([H])([H])N2C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
COC1=CC(=CC=C1OCCN1CCCC1)N1CC2=CC=C(SC3=C(F)C=C(F)C=C3)N=C2C1=O
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C21
[H]N(C(=O)C1=NN(C(=C1C([H])([H])C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C([H])N=C1Cl
[H]O[C@]1([H])[C@@]([H])(N([H])C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])S(=O)(=O)C([H])([H])[C@@]1([H])C([H])([H])C1=C([H])C(Br)=C(OC(=O)N([H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]11C(=O)N(C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(C(C(=O)C([H])([H])[H])=C(N1[H])C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])[C@]([H])(O[H])C([H])([H])N2[H])=C([H])C(N([H])[H])=C1[H])C1=C([H])C(Cl)=C([H])C(Br)=C1O[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])N=C([H])C(=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]