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[H]N([H])C1=NC2=C(C(=N1)C1=C([H])C([H])=C(Br)O1)C([H])([H])C1=C2C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
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[H]OC(=O)[C@]([H])(SC1=NN=C(N1C([H])([H])[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(N([H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])(OC3=C(C([H])=C([H])C([H])=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])=C([H])C([H])=N1
[H]O\N=C1\C2=C([H])C([H])=C(C([H])=C2C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N([H])C1=C(C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N1C(=O)N([H])[C@]2(N(C(=O)N([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])[H])C1=O
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[H]OC([H])([H])[C@@]1([H])N(C2=NC(=NC(=N2)N(C([H])([H])[H])C([H])([H])[H])N([H])C2=NC([H])([H])C3=C2C([H])([H])N(C(=O)N([H])[C@@]2([H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N1C(=O)N([H])[C@]2(C1=O)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C2([H])[H])C(F)(F)F
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[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C1=NC(=NN1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])\N=C1/N2C(=NC3=C([H])C(Cl)=C([H])C([H])=C13)C([H])([H])C([H])([H])C2([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])C1=C([H])C([H])=C([H])C2=C1C(=O)C1=C(N([H])N=C21)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]ON(C(=O)N([H])[H])[C@]([H])(C1=C([H])C2=C([H])C(=C([H])C([H])=C2S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])N1N=C(C2=C1C([H])([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(C(SC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H])C(F)(F)F)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2C#N)C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C(\[H])=C(/C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])(N1C([H])([H])C2=NC([H])=C(C3=NOC(=N3)C3=C([H])C(C#N)=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C3[H])C(=C2C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])O[H]
[H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[S@@+]([O-])C([H])([H])C(=O)C(F)(F)F
[H]C(=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=NN2C(=C1C1=C3C([H])=C([H])C(SC([H])([H])C([H])([H])[H])=C([H])C3=NC([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C1=NN(C([H])=C1C([H])([H])C1=C([H])C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C(Cl)C(=C(Cl)C([H])=C2[H])C([H])([H])OC2=C([H])C([H])=C([H])C3=NC(=C([H])N=C23)C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C([H])C(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C1=O
[H]OC1=NC([H])=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(N1C([H])([H])[H])C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C2N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1O[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC(=NC(C2=C([H])C([H])=C(F)C([H])=C2[H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C#CC1=C(OC2=C1C([H])=C(C([H])=C2[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C(OC([H])([H])[H])C([H])=C(SC([H])([H])[H])C(=C1[H])N(C1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=N\N=C(/[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(OS(=O)(=O)C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])=C([H])C(=C1[H])C([H])([H])[H])N([H])[H]
[H]C1=C([H])C([H])=C(S1)C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C2O1
[H]N([H])C1=NC([H])=NC2=C1C(=C(N2C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(O1)C1=C([H])C2=C(N=C([H])N=C2N([H])C([H])([H])C2=C([H])C([H])=C(O2)C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])(C([H])([H])O[H])C([H])([H])O[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C(N([H])S(=O)(=O)C2=C(\C([H])=C(\[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N1C(=O)C2=C(N=C1C1=C(C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(Br)=C([H])C([H])=C1O2
[H]OC(=O)C1=C(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2N1C([H])([H])C1=C([H])C2=NSN=C2C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C2=C(OC3=C([H])C([H])=C(C([H])=C3[H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])=NC([H])=C2S1
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])[C@]([H])(C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C2C3=C(N=C(C([H])=C3N(C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])N1C1=C(OC([H])([H])[H])N=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C(Cl)C([H])=C2C(N([H])C(SC([H])([H])[H])=NC([H])([H])C2([H])[H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])N1C(=NC(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
C[C@H](N)C(=O)N1C[C@H](F)C[C@H]1B(O)O
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(N([H])C2=NS(=O)(=O)N=C2N([H])[C@@]([H])(C2=C([H])C([H])=C(O2)C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])[C@]1([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(F)C([H])=C2[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C([H])N2N=C(N=C12)C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])N=C12
[H]OC(=O)C1=C([H])C2=C([H])C(OC(F)(F)F)=C([H])C(=C2O[C@]1([H])C(F)(F)F)C([H])([H])[H]
[H]N1N=C(C2=C3C1=C([H])C([H])=C([H])C3=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H]
[H]O[C@]1(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(N=C(N([H])C2=O)C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])SC2=C1C([H])=C([H])C([H])=C2[H]
[H]N1C([H])=NC2=C3N=C(N=C12)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])\C([H])=C([H])\C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C3=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C(Cl)=C(N([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C2=C1[H]
[H]C1=C(N=NN1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)N1C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N
[H]N(C(=O)C([H])([H])C([H])([H])[H])C1=NC(=C(N1[H])C1=C([H])C2=NC([H])=C([H])N=C2C([H])=C1[H])C1=NC(=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C([H])C([H])=C([H])C([H])=C1SC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])S1)C1=NC([H])=C(S1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])C([H])([H])C(=O)N1C(=O)[C@@]([H])(C1([H])[H])[C@]([H])(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OP(=O)(O[H])OC1=C2C(N([H])C([H])=C2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])SC([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N
[H]N1C(=O)C([H])=C(C2=C1C([H])=C([H])C1=C2C(=O)OC2=C1C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C(N([H])C([H])=N2)C(=N1)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2C(=O)OC([H])([H])C2=C(C(OC([H])([H])[H])=C1C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=NC(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C(=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C2N=C(C([H])=C(C2=C1[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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OC1=C(SC2=CC=CC=C2)C=C(NS(=O)(=O)C2=CC=CS2)C2=CC=CC=C12
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[H]N1C([H])=C(C2=C(OC([H])([H])[H])C([H])=C([H])N=C12)C1=NC(SC([H])([H])[H])=NC([H])=C1[H]
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[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NN(C([H])=C1C1=C([H])C([H])=NC2=C1C([H])=C([H])N2[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C(C([H])=C([H])C(Cl)=C1F)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC1=C2O[C@@]3([H])C4=C(C5=C(C([H])=C([H])C([H])=C5[H])N4C([H])([H])C4=C(N=C=S)C([H])=C([H])C([H])=C4[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]C1=C(C(=O)C2(O1)C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=C(N=NN2C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
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[H]C([H])=C=C([H])C(=O)N([H])C1=C([H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])C2=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C([H])([H])N1C([H])([H])C([H])([H])N(C(=S)SC2=C(C([H])=C(C([H])=C2[H])[N+]([O-])=O)[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(S1)C(=O)C([H])([H])[C@@]([H])(C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])(C#N)C#N
[H]N(C(=O)C1=C([H])N=C2N=C([H])C([H])=C([H])N12)[C@@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(OC2=NC(=C(C#N)C([H])=C2[H])C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=N1)[C@@]([H])(N1C([H])([H])C([H])([H])N3C(=O)C([H])([H])C([H])([H])[C@@]3([H])C1([H])[H])C1=C(C([H])=C(Cl)C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])Cl)C1=C([H])C(=C(S1)C1=NN=C2SC3=C(N=C4C([H])=C([H])C([H])=C([H])C4=N3)N([H])N12)C([H])([H])[H]
[H]N1C(=O)N(C2=C(C(=C([H])C(=C2[H])C(=O)OC([H])([H])[H])C2=C(F)C([H])=C([H])C([H])=C2F)C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC([H])([H])C([H])([H])[C@]1([H])N(C(=O)C([H])([H])[C@]([H])(N([H])[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)C([H])([H])C([H])([H])C2=C1C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC(OC([H])([H])[H])=NC(=N2)N([H])C([H])([H])C#N)=C1[H]
[H]N1C2=C(C(=NN2C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(S[C@]([H])(C1=O)C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])OC(=O)C2=C([H])C(Cl)=C([H])C3=C2N=C([H])N3[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C(=C23)C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(N=C2N(C(=O)C(C(=O)C([H])([H])[H])=C(N(C([H])([H])[H])C([H])([H])[H])C2=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1(N2C([H])([H])C([H])([H])N(C(=O)[C@@]3([H])C([H])([H])N(C([H])([H])[C@]3([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C1=C2C(=NC3=C(C([H])=C(OC([H])([H])[H])C([H])=C13)C([H])([H])[H])N([H])N=C2C([H])([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC(Cl)=NC([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H])[C@](C1=C([H])C([H])=NC([H])=C1[H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
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[H]C1=C(Br)C([H])=C2C(=N1)C(C1=C(C([H])=C(Cl)C([H])=C1Br)C([H])([H])C2([H])[H])=C1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C([H])=[N+]([O-])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]O[C@@]([H])(C(=O)C1=C(F)C([H])=C([H])C(F)=C1[H])C1=C([H])C(F)=C([H])C([H])=C1F
[H]N([H])C(=O)C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
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[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C([H])N=C1[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C1=C([H])C2=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])C1=NC([H])([H])C([H])([H])N1[H])C2=O
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C2C(=NN([H])C2=N1)N([H])C(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(O2)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]N([H])C(=O)N([H])C1=C(C([H])=C(S1)C#CC1=C([H])C([H])=C([H])C(N([H])C(=O)C2=C([H])C([H])=NC([H])=C2[H])=C1[H])C(=O)N([H])[H]
[H]N(C1=C([H])C([H])=C2SC(=C([H])C2=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C1=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C([H])C2=NC([H])=N1
[H]C1=C([H])C([H])=C(O1)C(=O)N1C([H])([H])C([H])([H])N(C2=C3C(SC4=C3C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C4([H])[H])=NC(=N2)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N=C(OC2=C1[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N([H])C1=NC([H])=NN2C(=NC(=C12)C1=C(F)C2=C(C([H])=C([H])C(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])[C@]1([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OP(=O)(O[H])C([H])(N([H])C1=C([H])C(=C([H])C([H])=N1)C1=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])P(=O)(O[H])O[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])[C@]1([H])O[H])C1=C([H])C([H])=C(Cl)C(=C1[H])C([H])([H])C1=NC([H])=C(SC([H])([H])[H])C([H])=N1
[H]\C(=C(\[H])[C@@]1([H])C2=C(C([H])=C(F)C([H])=C2[H])C([H])([H])[C@]2([H])C(=O)OC([H])([H])[C@]12[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C1=NC2=C(N=C([H])N=C2N([H])[H])N=C1[H])C(=O)O[H]
[H]N([H])C1=C(Cl)C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C(=O)C([H])([H])Br
[H]C1=NC(=C([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=N1)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC([H])([H])C1=C(N2C([H])=C([H])C([H])=C2[H])N(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C(C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[H])C1=C([H])C(=O)C(=O)C2=C([H])C([H])=C([H])C([H])=C12
[H]OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C(=C2[H])C2=C([H])C([H])=C(SC3=C(C([H])=C([H])C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)N([H])[H]
OC(C1=CN=C(S1)N1CCN(CC1)C1=CC=C(C=C1)[N+]([O-])=O)(C(F)(F)F)C(F)(F)F
[H]C1=C([H])C([H])=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C(=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=NC2=C([H])C(Cl)=C([H])C([H])=C2C(OC([H])([H])C#N)=C1C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])C([H])([H])Cl)C([H])([H])C([H])([H])Cl
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(C(=O)O[H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N2C([H])=C([H])C(=C([H])C2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=N1
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(N([H])C([H])([H])C(=O)N([H])C3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(O[C@]([H])(N2C(=O)C([H])([H])C([H])([H])[H])C2=C([H])C(Br)=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])[H])=C2[H])N=C(SC([H])([H])[H])N=N1
[H]C1=NN(C(=O)C(Cl)=C1OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(\C(=N/S(=O)(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H])N1N=C([H])[C@]([H])(C([H])([H])C([H])([H])[H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])N=C(O[C@]2([H])C([H])([H])[H])C2=C([H])C(Br)=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C1=N\C(=C(\[H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C(=O)N1C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C3=NOC(=N3)C3=C([H])C([H])=C([H])C([H])=C3[H])C(F)=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])N([H])C([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]2([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C2([H])[H]
FCC(CN1CCC2(CC1)OCCC1=C2SC=C1)CC1=CC=CC=C1Cl
[H]OC(=O)[C@@]([H])(OC1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])[C@]1(N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(F)(F)F
[H]OC(=O)[C@@]1([H])N(C(=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2C1([H])[H]
[H]OC(=O)[C@]([H])(\N=C(/S[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1[C@@]2([H])C(C(=O)N(C([H])([H])C3=C(Cl)C(Cl)=C([H])C([H])=C3[H])C3([H])C([H])([H])C3([H])[H])=C(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])OC4=C([H])C(Cl)=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])[C@]1([H])C([H])([H])N(C(=O)C([H])([H])[H])C2([H])[H]
[H]C1=C([H])C([H])=C(C(=O)N2C([H])([H])C([H])([H])C([H])(C(=O)C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C(F)=C1[H]
[H]C([H])=C(C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C(OC(F)(F)F)C([H])=C1[H])S(=O)(=O)C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C(F)=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])S[C@@]2([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])OC3=C2C([H])=C(C([H])=C3[H])C([O-])=O)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
CCNC(=O)[C@H]1CC[C@](CO[C@H](C)C2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)(NC1)C1=CC=CC=C1
[H]OC1=C(I)C([H])=C2C(=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C2([H])[H])[C@@]1([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N(C2=NC([H])=NC(N([H])[H])=C12)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])[H])S(=O)(=O)C2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C2C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])N(C2=NN3C([H])=C([H])C([H])=C3C(=N2)N([H])C2=NN([H])C(=C2[H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])N=C(F)C([H])=C1[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])N1C(=O)N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NN(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])N2C([H])=C([H])N=C2C1([H])[H]
OC[C@H]1OC([C@H](O)[C@@H](O)[C@@H]1O)C1=CC(CC2=NN=C(S2)\C=C\C2=CC=CC=C2)=C(Cl)C=C1
[H]N(C1=C(Cl)C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])C3=C(N=C([H])N3[H])C([H])=C12
[H]N([H])C1=NC2=C(S1)C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=NC2=C(N=C([H])N2C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])N1C(=O)C(Cl)=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1=O
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=NC([H])=C1[H])C1=C(OS(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C1=C([H])N=C(N=C1[H])N([H])C1=NN=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
COC1=NC(C(=O)NCC2CCC2)=C(NC(=O)C2=C3C=CC=CC3=NC=C2)C=C1
[H]N(C1=NC(=NC2=NC([H])=C(C([H])=C12)C1=C([H])N(N=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=C(Cl)C(F)=C([H])C([H])=C1Cl
[H]N([H])C1=NC2=C(C([H])=C(\C([H])=C(/[H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])=N2)C(=N1)N([H])[H]
[H]O[C@@]([H])(C([H])([H])[H])[C@]([H])(N1C([H])=NC2=C(N=C([H])N=C12)N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
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COC1=CC=C(C=C1)N1C=C2N=C(N=C(N)C2=N1)C1=CC=CC=C1
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[H]C1=C([H])C([H])=C(S1)C1=NC(Cl)=NC2=C1SC([H])=C2[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N([H])C1=NN(C(=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@](C#CC1=C([H])C([H])=C(C#N)C([H])=C1[H])(C1=C([H])N=C([H])N1C([H])([H])[H])C1=C([H])C([H])=C(C#N)C(=C1[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(C(=O)O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]C1=C([H])C(=C(Cl)C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]N(C(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])=O)C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C([H])=NC2=C(C1=O)C(N([H])C1=C([H])C([H])=C(I)C([H])=C1F)=C(Cl)C(=O)N2C([H])([H])[H]
[H]N(C(=O)C#CC([H])([H])[H])C1=C([H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]C([H])([H])[C@@]1([H])O[C@@]([H])(C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=O
[H]OC(=O)C1=C([H])C([H])=C(S1)C(=O)C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1Cl)C1=C(C#N)C(=O)N(C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])SC1=C([H])C2=C3C(=C1[H])C1=C(C([H])=C([H])C(O[H])=C1O[H])C([H])([H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C1=NC2=C(N=C(C([H])=C2[H])C([H])([H])N([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C(=N1)N([H])[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])C([H])=C([H])C1=C(C([H])=C(C([H])=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C2=O)S(=O)(=O)C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N([H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NC([H])=C([H])S1
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)O[H])C1=C([H])C(C2=NC3=C([H])C(=C([H])C([H])=C3N2[H])C(=N[H])N([H])[H])=C(O[H])C(=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])O[H]
[H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C1(C(=O)OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(Cl)C([H])=C(\C([H])=C2/S\C(=N/N(C([H])([H])[H])C([H])([H])[H])N(C2=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(I)=C(N([H])C(=O)C([H])([H])N([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C([H])([H])[H])C([H])([H])C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2C(O[C@@]1([H])C([H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(F)=C([H])C(C#N)=C1[H]
[H]\C(=C1\SC(=S)N(C1=O)C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O\C(OC([H])([H])C([H])([H])[H])=C1\C(=NC(=C(C(=O)N([H])C2=NC([H])=C([H])C([H])=C2[H])[C@@]1([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])OC([H])([H])C([H])([H])N1C(=NC2=C1C([H])=C([H])C([H])=N2)C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=C([H])C([H])=C1\C([H])=C1/SC(=O)N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N([H])C(=O)C([H])([H])N1C([H])([H])C([H])(C([H])([H])N2N=C([H])C(=C2[H])C2=C([H])C(O[C@]([H])(C3=C(Cl)C([H])=C([H])C(F)=C3Cl)C([H])([H])[H])=C(N=C2[H])N([H])[H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
O=C(NCC1=CC=CC=C1)C1=CC=C2NC(=NC2=C1)C1=CC=C(OC2=CC=CC=C2)C=C1
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]C#CC1=C2C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C2=C([H])C([H])=C(Cl)C([H])=C2C2=C1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]N1C([H])=C([H])C2=C([H])C([H])=C3C(=C12)C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=N2)C([H])([H])C1=C([H])C([H])=C([H])S1)C([H])([H])[H]
[H]OC1=C2C([H])=C([H])C([H])=C([H])C2=C2C(=N1)C([H])([H])C([H])([H])N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N=C2C(C([H])=C([H])C([H])=C2C(F)(F)F)=C1C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(C#N)(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NC(SC([H])([H])[H])=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C(N([H])C2=NC([H])=NC3=C2N([H])C([H])([H])C2=C(O3)C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])=N1
[H]N1C2=C(C([H])=C1C1=C([H])C3=C(N([H])C1=O)C([H])=C([H])C([H])=C3[H])C([H])=C(OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)C1=NC(=C(S1)C(=O)N([H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N1C(=O)N(C2=C([H])C([H])=NC([H])=C2C1=O)C([H])([H])C1=C([H])N(C2=C1C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=NSC(N([H])C2=C([H])C([H])=C(OC3=C(Cl)C(=C([H])C([H])=C3[H])C(F)(F)F)C(Cl)=C2[H])=C1\C(=N\[C@]([H])(C([H])([H])[H])C([H])([H])O[H])N([H])[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(\C([H])=N\C([H])([H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C(O1)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C(O1)C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(N=C(C([H])=N1)C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)N([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])N(C(=O)C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C(ON=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)OC1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])N1C(=NC2=C([H])C(=C([H])C([H])=C12)N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])N([H])C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]C1=C([H])C2=C(OC1=O)C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N(C(=C(C1=O)C([H])([H])N(C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C(F)C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]OC1=C(O[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3=C1C2=C([H])C(OC([H])([H])C([H])([H])[H])=C3[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl)C1=C([H])C(=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@@]1([H])N([H])C(=S)N([H])C(=C1C(=O)OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])S[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C2=C1C1=C([H])C([H])=C([H])C([H])=C1[N+](=C2[H])C([H])([H])[H]
OB(O)C1=CC=CC(=C1)C1=CC=CC=C1
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C([H])=C4N([H])C([H])([H])C([H])([H])C4=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C1[H])C2([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(OC3=NC(=NC(=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C3=C([H])C([H])=NC([H])=C3[H])C([H])=C([H])C([H])=C2S1
[H]N1C(C#N)=C([H])C2=C1[C@]([H])(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2N1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(/[H])C2=C([H])C(Br)=C(OC([H])([H])[H])C([H])=C2[H])C1=O
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(OC3=C([H])C(F)=C([H])C([H])=C3C([H])([H])[H])N(C3=C([H])C(OC([H])([H])[H])=NC([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC([H])([H])C1=C([H])N(N=N1)C([H])([H])C([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(Cl)=C([H])C([H])=C2N2C([H])=C([H])C([H])=C12)C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C([H])C(F)=C2[H])=N1
[H]N(C(=O)C1=C([H])C2=C(C([H])=C([H])S2)N1C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])C(=O)C([H])([H])C([H])([H])[C@@]4(N([H])C(=O)C(\[H])=C(/[H])C(=O)OC([H])([H])[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]N([H])C1=NC([H])=C([H])C2=C([H])C([H])=C(OC3=C(N([H])C(=O)C4=C([H])C([H])=C(C([H])=C4[H])C4=C([H])C([H])=C([H])C([H])=C4S(=O)(=O)N([H])[H])C([H])=C(F)C([H])=C3[H])C([H])=C12
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N2C(=O)[C@]3([H])N(N([H])C([H])([H])C([H])([H])C3([H])[H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]3([H])N(C(=O)[C@]([H])(N(C(=O)[C@]2([H])C([H])([H])C([H])([H])C1=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])[C@@]([H])(O[H])C([H])([H])N2[H])=C([H])N=C1[H])C1=C([H])C(Cl)=C([H])C(I)=C1O[H]
[H]OC([H])([H])C([H])([H])C([H])([H])OC1=C(C([H])=NC(=C1[H])N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)C([H])([H])[C@@]([H])(C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N([H])C([H])([H])[H]
[H]N(C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@]1([H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)S(=O)(=O)C(F)(F)F
[H]OC(=O)C([H])([H])[C@]([H])(N1C(=O)N(C2=C([H])C([H])=C([H])N=C2C1=O)C([H])([H])C1=C([H])N(C2=C1C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=O)OC([H])([H])C2=C([H])C(=O)C(OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C([H])O2)C(OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
CC1=C(OC2=C1C=C(C=C2)C1=CC=CC=C1)C(=O)NC1=CN=C(C=C1)N1CCC(CC1)OCC1=CC=CC(=C1)C(O)=O
[H]C1=NC([H])=C(N=C1[H])C([H])([H])C1=C(C([H])([H])C([H])([H])N2C([H])([H])C(F)(F)C2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])SSC([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])S[C@@]([H])(N(C1=O)C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C(N1C([H])([H])[H])C([H])([H])[H]
O=C(NC1CCN(CC1)C1=NC(=NS1)C1=CC=CC=C1)NC1=NOC2=C1C=CC=C2
[H]OC1=C(C(OC([H])([H])[H])=C(C2=C1C(=O)OC2([H])[H])C([H])([H])[H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])O[H]
[H]N(C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])S(=O)(=O)N1C([H])=C(C2=C([H])C(Cl)=C([H])N=C12)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C(C#N)C#N)C([H])=C1C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(OC([H])([H])[C@]2([H])N([H])[C@]([H])(C(=O)N3C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C#N)C([H])([H])C2([H])[H])C(Br)=C1[H]
[H]OC(=O)C1=C([H])C(=O)[C@](O1)(C1=C([H])C([H])=C(S1)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C2=C([H])C([H])=C(C(F)=C2[H])C([H])([H])N2C(OC([H])([H])C([H])([H])C([H])([H])[H])=C([H])C(=O)N(C2=O)C([H])([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(=C1[H])C1=NOC([O-])=N1
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])[C@]1(C2=C(C(=O)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(Cl)C2=C(N=C1[H])N(N=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])C(=NC([H])=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1F)N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C1=NN([H])N=N1)C([H])([H])[H]
[H]C1=NC(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C1=NC2=C([H])C(OC([H])([H])[H])=C([H])C(=C2C(=O)O1)C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=C(OCCC2=C(OCC3=CC=CC=C3)C=CC(=C2)C(O)(C(O)=O)C(F)(F)F)SC(=N1)C1=CC=C(Cl)C=C1
[H]N(C(=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C(S1)N(C(=O)N(C2=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C(=C1[H])N1C(=O)C2=C(N=C1C([H])([H])[H])C([H])=C([H])C(=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(N=N1)C([H])([H])C([H])([H])C([H])([H])C#N
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]2([H])N(C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)N([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])N(C(=O)N(C([H])([H])C2=C([H])N=C([H])S2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[C@]1([H])N([H])C(=O)N([H])C1=O
[H]N(N([H])C1=C2C([H])=C([H])C(=C(C2=NC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C2=C(OC([H])([H])C1([H])[H])C([H])=C(OC1=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C13)C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C2O[C@@]3([H])C4=C(C5=C(N4[H])C([H])=C([H])C([H])=C5[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]OC([H])([H])C([H])([H])OC1=NC(=NC(N([H])S(=O)(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1OC1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=NC([H])=C([H])C([H])=N1
OC1=C(O)C=C(\C=C\C(=O)NC2=CC=CC(F)=C2)C=C1
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C([H])C(=C([H])N=C1N([H])C1=C([H])C([H])=C(Cl)N=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])N(C([H])([H])[H])[C@@]([H])(N2[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=NC=C(C=N1)C1=NC2=C(C)N=C(N)N=C2N(C(C)C)C1=O
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=NN=C(O1)C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2OC(=O)\C(=C(/[H])C3=C([H])C(O[H])=C(O[H])C(O[H])=C3[H])C2=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(F)(F)C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1(C(=O)N([H])[C@@]2([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)O[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C2O[C@@]3([H])C4=NN([H])C([H])=C4C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C(=C([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N1C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])OC(=C([H])C1=O)C([H])([H])SC([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C#CC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C2=C(N=C([H])N=C2N([H])C2=C([H])C(Cl)=C(F)C([H])=C2[H])C([H])=N1
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2Cl)[C@]1([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C1=NOC(=N1)[C@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CCC[C@@H]1CC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N1CCC[C@@H]1C(N)=O
[H]OC(=O)C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])C3(C([H])([H])N(C4=C([H])C([H])=NC([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(=NS1)C([H])(C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C([H])N2C1=NC([H])=C2C1=C([H])N(N=C1[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C1C1=C([H])C3=C(N([H])C1=O)C([H])=C([H])C([H])=C3[H])C([H])=C(C([H])=C2[H])S(=O)(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C([H])=C(C1=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C1=C([H])C(F)=C(OC2=C3C([H])=C([H])N([H])C3=NC([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=C(Cl)C(OC2=C(F)C([H])=C(N([H])C(=O)C3=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])N(C3=O)C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])=C([H])C([H])=N1
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C(=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[H]
[H]N1C(=C([H])C2=C1C1(C([H])([H])N([H])C2=O)C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC(=N1)C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C2=C1C(=O)C1=C(N([H])N=C21)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1N(C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(O[H])C2(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1=O
[H]N(C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC([H])=C(SC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])S1
[H]N(C1=C([H])C(=C([H])C([H])=C1F)C1=C2C(=C(N1[H])C1=C([H])C(N([H])C([H])([H])[H])=C(F)C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=C(C2=C([H])SC(=N2)C2=C([H])C3=C(OC([H])([H])C3([H])[H])C([H])=C2[H])C1=O)C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]N(C(=O)OC([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C2=C([H])C(=NC([H])=N2)N([H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C(=NN([H])C1=O)C1=C([H])N(C(=O)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=C([H])C(=NC([H])=C2C([H])=C1C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C1C(Cl)=C([H])C1=C2[C@@]([H])(C2=NC([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C([H])=[N+]([O-])C([H])=C2[H])C([H])([H])C1([H])[H]
CN1N=NC(CC2=CC=C3N(C=C(C4CCN(CCN5CCNC5=O)CC4)C3=C2)C2=CC=C(F)C=C2)=N1
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])C(OC([H])([H])[H])(OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)O1)C([H])([H])C([H])([H])C#N
[H]N([H])C1=C2C([H])=C(SC2=C(C([H])=N1)C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(O[H])C(=O)C([H])=C([H])C([H])=C1C([H])([H])C(=O)O[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C2([H])C([H])([H])C2([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(Cl)N=C2N([H])C([H])([H])C1=C([H])C([H])=C([H])C(I)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1SC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])N2C([H])=C([H])C([H])=C2C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(N([H])S(=O)(=O)C3=C([H])C([H])=C(F)C([H])=C3[H])=C2[H])N(C2=C([H])C3=C(C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC(=C1[H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C(N([H])C([H])=N2)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C(C([H])=NC2=C1[H])[C@]1([H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C1=NC(=NO1)[C@@]1([H])N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1(C([H])([H])C2=C([H])C(=C(C([H])=C2[H])N2C(=O)C3=C(OC([H])([H])C(F)(F)F)C4=C([H])C([H])=C([H])N=C4C(OC([H])([H])C(F)(F)F)=C3C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
COC1=CC=C(NC(=O)NC2CCN(CC3=CC=C(C=C3)C3=NN=C4N3C3=CC=CN=C3NC3=C4C=CC=C3)CC2)C(C)=C1
[H]N1C([H])=C(C2=C([H])C(OS(=O)(=O)C(F)(F)F)=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=NC(=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O
CC(C)N1CCC(CC1)OC1=CC=C2N3CCN(CC4CC4)C(=O)C3=CC2=C1
[H]C1=NN(N=C1[H])C1=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C1C(=O)N1C([H])([H])[C@]([H])(OC2=NC([H])=C([H])C(C#N)=C2[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=C([H])C([H])=C([H])C3=C2C(=C([H])N3[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=NC(SC([H])([H])[H])=N1
[H]\C(=C(/[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]SC1=NC(=NN1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])([H])[C@@]2([H])C([H])([H])N(C3=NC([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]C1=C2OC(=O)C(=C([H])C2=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C1=C(Cl)C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])N(C2=C3C(OC([H])([H])C3([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(Cl)=C(SC2=NC([H])=C([H])N2C([H])([H])[H])C([H])=C1[H])C1=C(C#N)C([H])=NC2=C1C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])S(=O)C([H])([H])C1([H])[H])=C2[H]
C(COC1=NC2=C(CCN(CC3=CC=CC=C3)C2)S1)CN1CCCCC1
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C(C([H])=C(C([H])=C1[H])C([H])([H])OC1=C2C(=NC(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1[H])C([H])([H])[C@@](N([H])C([H])([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(N([H])C(=C(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C(C(=O)OC([H])([H])C([H])([H])[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C(C([H])=NC([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N(C([H])([H])C([H])([H])OC1=C([H])C(F)=C([H])C2=C1OC([H])([H])C([H])([H])C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])N1C2=C([H])C([H])=C([H])C(C3=C([H])C(OC(F)(F)F)=C([H])C([H])=C3[H])=C2OC([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C(OC(F)(F)C([H])(F)F)=C1[H])C(F)(F)F
[H]OC([H])([H])C1=C([H])C2=C(C([H])=C([H])N2C2=NC3=C(C#N)C([H])=NN3C(N([H])C3([H])C([H])([H])C3([H])[H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])C4=C(C([H])=C(C([H])=N4)C4=C([H])C([H])=C(Cl)C([H])=C4[H])C([H])([H])[C@@]4(OC([H])([H])C(\[H])=C(/[H])C5=C([H])C([H])=C([H])C([H])=C5[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
C[C@H](OC1=C(Cl)C(Cl)=CC=C1)C(=O)NC1=CC=C2OC(=NC2=C1)C1=CN=CS1
[H]N1C(=O)[C@@]2([H])N(C3=C([H])C(F)=C(F)C([H])=C13)C([H])([H])C([H])([H])N([H])C2([H])[H]
[H]\C(=C(\[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=NC(=NC2=C([H])C([H])=C([H])C([H])=C12)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2OC([H])([H])C([H])([H])F)C([H])([H])C1([H])[H]
CCNC1=NC(C(N)=O)=C2CN(CCC2=N1)C(=O)CCC1=CC=C(C)C=C1