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[H]O[C@]1([H])C([H])([H])C2=C(N(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C(=C([H])C([H])=C1Br)C1=C(C2=NN=C(O2)C([H])([H])[H])C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=C(S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C(Cl)=C(O1)C1=NC(=NO1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]N(C(=O)OC([H])([H])C1=C(F)C([H])=C([H])C([H])=C1Cl)C1=C(ON=C1C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]N([H])C1=NC([H])=C(C(=N1)N([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@@]1([H])\C(=N/OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]ON1C(C([H])=C(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C(=O)N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C(=O)O[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C1(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])N([H])C(=O)N2C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])SC(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C2=NC(=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C2C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C(OC1=C(C#N)C([H])=NC3=C1C([H])=C(S3)C1=C([H])C([H])=C([H])C([H])=C1[H])=C2[H]
[H]OC1=C([H])C([H])=C2N([H])C(=NC2=C1C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])S1)C1=C([H])C([H])=C([H])C(F)=C1F
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(C([H])=C3N(C(=NC3=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])O1)[C@]1([H])OC(=O)[C@]2([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[C@]([H])(OC([H])([H])OC([H])([H])C([H])([H])[H])C(=O)[C@]3([H])[C@@]2(C([H])([H])[H])C1([H])[H]
C\C(=N/OCC1=CC(=C(C=C1)C1=CC=C(C)C=C1)C(F)(F)F)C1=CC=C(CNCCC(O)=O)C=C1
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CN1C2=C(C=CC=C2)C(=C1S(=O)(=O)C1=C(F)C=CC=C1)S(=O)(=O)N1CCC(CNS(=O)(=O)C(F)(F)F)CC1
[H]N1C2=C(SC3=C2N=C(Cl)C([H])=C3[H])C(=O)N(C1=O)C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC1=NC2=C(C([H])=C3C(N([H])[C@]([H])(C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C3([H])[H])=C2[H])C(=C1[H])C(F)(F)F
CCC1=NC2=C(N1[C@H]1CCC3=C1C=CC(=C3)C1=CC=CC=C1C1=NN=NN1)C(=O)N(CC1=CC=NC=C1)C=C2
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[H]N(C(=O)C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]C1=C([H])C2=C(C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]21[H]
[H]C([H])=C(C([H])([H])[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
OC(=O)C1=C(CCCOC2=CC=CC3=CC=CC=C23)C2=CC=CC=C2N1
[H]O[C@@]([H])(C([H])([H])N(C1=C([H])C(=C([H])C([H])=C1[H])C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(OC(F)(F)C([H])(F)F)=C([H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])O[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]N(C1=C([H])C([H])=C2C(=O)C3=C4C(=NC([H])=C([H])C4=C([H])C([H])=C3[H])C2=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]O\N=C1/C2=C(C([H])=C(C([H])=C2[H])C2=C([H])N(N=C2C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)N([H])C1=C(Cl)C([H])=C([H])C(=C1[H])C(F)(F)F)C1=C([H])C([H])=C(OC2=C([H])C([H])=NC(=C2[H])C2=NC([H])=C(N2[H])C(F)(F)F)C([H])=C1[H]
CCC1=C(C=CC=C1CCCC(O)=O)C1=NC=C(C=N1)C1=CC=C(OC(C)C)C(=C1)C#N
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[H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])=C2[H]
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[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(\C(S1)=N\C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
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[H]N([H])C1=NON=C1C1=NC2=C([H])C(N([H])[H])=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
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[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2C3=C(C4=C([H])C([H])=C(C(F)=C4N3[H])C3=C([H])C([H])=C(F)C(=C3[H])C([H])([H])[H])C([H])([H])C2=C1[H]
[H]C1=C(N=C(S1)C([H])([H])[H])C#CC1=C([H])C(I)=C([H])C(C#N)=C1[H]
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[H]O[C@]([H])(C([H])([H])S(=O)(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C([H])([H])C2=C1C([H])=C1ON=C(C1=C2[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]OC([H])([H])C([H])([H])C([H])([H])C1=C(C(=NC(=N1)N([H])[H])N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC([H])=NC2=C1N=C(Br)N2C([H])([H])C([H])=C([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)N1C([H])=C(N=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C3C1=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C2C3=C4C(C([H])=C([H])C([H])=C4C(=O)C2=C1[H])=C([H])C([H])=N3
[H]N([H])C(=O)C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])C([H])=C(OC([H])([H])[C@]2([H])C([H])([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3(SC2([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=C(C(=O)N([H])C2([H])C([H])([H])C2([H])[H])C(=O)C2=C([H])C([H])=C([H])N=C12)(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(N=NN2C2=C1SC([H])=C2[H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])C#CC([H])([H])N1OC([H])([H])C([H])([H])C1=O
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C#C[H])[C@]1([H])C2=C([H])C3=C(N=C(N=C3O[H])C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H])C(=O)O[H])C1=NN([H])N=N1
[H]C1=C2C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C1OC([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C(Cl)N=C23)N([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])O[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]C([H])=C([H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C(Br)C(OC([H])([H])[H])=C2C2=C1C1=C(N([H])C(C([H])=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N2C([H])([H])[C@]([H])(O[H])C([H])([H])[C@@]2([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])O[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C([H])([H])C(=O)N([H])[H]
[H]C([H])=C([H])C([H])([H])N(C(=O)OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N2N=C([H])N=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)C1=NN2C(=N1)C1=C([H])N(N=C1N=C2N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NN=C(S1)C1=C([H])C(=C(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NN([H])C(=C2[H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])[C@]([H])(N(C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[C@@]1([H])O[C@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C(=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])SC([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])[C@@]2([H])C(=O)C3=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)C1=NC(=C(S1)C1=NOC([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(=NO1)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)S(=O)(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C2=C(C([H])=C1[H])N(C(=C2[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])=C(C(=O)C(F)(F)F)C2=C1C1=C(C([H])=C2[H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])=C([H])C([H])=C1C2=O
[H]N1C2=C(C([H])=C(C([H])=N2)C2=C([H])C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])C([H])([H])[H])N(C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])N([H])C([H])([H])C([H])([H])[H])[C@@]([H])(N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C(C([H])=C3C([H])=C2[H])[N+]([O-])=O)[C@]([H])(C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C2=C([H])C(C#CC([H])([H])C([H])([H])N3C([H])([H])C([H])=C(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])=C([H])C([H])=C2O1
[H]OC(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(C([H])=C2[H])C(Cl)=C(S3)C(=O)N([H])C2=C(C([H])=C(Cl)C([H])=C2[H])C(=O)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C2C([H])=NN(C2=NC([H])=C1C(=O)O[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1(O[C@]([H])(C([H])([H])[H])[C@]([H])(O1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2O[C@]3([H])[C@@]([H])(N([H])C(=O)C4=C([H])C([H])=C(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])[C@]4(O[H])[C@@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])S1
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])[C@]1([H])N(C(=O)C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1N1C([H])([H])C([H])([H])C2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=S)C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])[C@@]1([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C3=C([H])C([H])=NC(=N3)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(Cl)S1
[H]N(C1=C2N=C(N([H])C2=NC([H])=N1)C1=C([H])C([H])=C([H])C(C#N)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(Cl)C([H])=C(Cl)C(=C1[H])N1C2=C(N(C(=N2)C([H])([H])C([H])([H])[H])C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C2C(=NC3=C(C(=NN13)C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1OC([H])([H])[H])[C@]1([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])OC2=C(C([H])=C(O[H])C([H])=C2[H])[C@@]2([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[C@@]12[H]
[H]O[C@]([H])(C([H])([H])N(C(=O)C1=C([H])C2=C(N=C(O2)N([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])N=C([H])S1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)C2=C([H])C(=C([H])C(=C2[H])C(=O)N([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])OC2=C([H])C(F)=C([H])C(F)=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C(=O)O[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1\C([H])=C1/N([H])C(=O)N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])SC2=C([H])C(O[H])=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1N=C(C(=C1[H])C1=C([H])C([H])=C2N=C(C(=NC2=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]1([H])C(=O)N2[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C(N=C1C1=C([H])C([H])=C(C([H])=C1[H])S([O-])(=O)=O)C(=O)N(C(=O)N2[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(S1)N(C([H])([H])C([H])=C([H])[H])C([H])([H])C1=C([H])C2=C(N=C(N([H])C2=O)C([H])([H])[H])C([H])=C1[H])C(=O)O[H]
[H]C1=NN(C(=C1[H])C1=NN(C([H])=C([H])C1=O)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])C1=C(C([H])=C([H])C([H])=N1)C(=O)C1=NC(=C([H])C([H])=C1Cl)N1C([H])([H])C([H])([H])N([H])[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=O)[C@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N([H])[H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(C#N)=C(C([H])=C1N1C(=S)N(C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C(C1=O)(C([H])([H])[H])C([H])([H])[H])C(F)(F)F