[H]C1=C([H])C2=C(C([H])=C1[H])C(=C([H])N=N2)C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C(SC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N([H])C1=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C2([H])[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)N1C(=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC([H])=C1C([H])([H])[H])N([H])C([H])([H])C(F)(F)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])SSC([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C([H])=O)[C@]([H])(O[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl)C1=C([H])C(=NN1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C(=O)N(C2=C1C([H])=NN2C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C(=O)N([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C(C([H])=C(Cl)C([H])=C2[H])N1S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1Br
[H]OC(=O)[C@@]1([H])N(C(=O)[C@@]([H])([S@+]([O-])[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H]
[H]O[C@@]1(C([H])([H])C(=O)C2=C([H])C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3S2)C([H])([H])C([H])([H])[N@+](C([H])([H])[H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(N=C(N2N=C1C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])(C(=O)O[H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])[S@@](=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C(N([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C(=O)N([H])[H])C(=O)N([H])[H]
[H]C(=O)C1=C(SC([H])([H])C([H])([H])C([H])([H])[H])C2=C(C3=C(S2)N=C2N(C3=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)N(C2=NC([H])=C([H])N2C([H])([H])[H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1Cl)C(F)(F)F
[H]C1=NC([H])=C(S1)[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])=C2[H])[C@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]\C(=C1\OC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C(N=C(S1)C([H])([H])[H])C#CC1=C([H])C(I)=C([H])C(C#N)=C1[H]
[H]N([H])C(=S)N([H])\N=C(/C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]2([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C3([H])[H])[C@]([H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])[C@@]([H])(N(C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N1C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C(OC([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])=N1
[H]N(C(=O)N([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N2C([H])=C([H])N=C2C(=N1)N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C1=NC([H])=NN2C1=C(C(Cl)=C2[C@]1([H])C([H])([H])N(C(=O)C([H])=C([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C(C#N)=C2[H])C11C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(\C([H])=C(/[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(=C([H])N1[H])C1=NN([H])C([H])=C1C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]C1=C2C(=C([H])O1)[C@]([H])(C1=C([H])C3=C(OC([H])([H])O3)C([H])=C1[H])C1=C([H])C3=C(OC([H])([H])O3)C([H])=C1C2([H])[H]
[H]C1=C(OC(=N1)[C@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)N(C1=O)C([H])([H])C(=O)N([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([O-])=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])OC([H])([H])[H])C2=C(F)C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
[H]N1C(=NC(C2=C([H])C([H])=C(F)C([H])=C2[H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC([H])=C([H])C(C#N)=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])C([H])([H])[H])N1N=NC([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1O[H])C1=C([H])C([H])=C(S1)C(\[H])=C1/SC(=O)N(C1=O)C([H])([H])C(=O)O[H]
[H]N(C(=O)N([H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])N(C(=O)[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2=C(Cl)C([H])=C(C([H])=C2Cl)C([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=NC([H])=C1[H])C(=O)OC([H])([H])[H]
[H]OC([H])([H])[C@]([H])(C#CC1=C2C(N([H])C(=O)\C2=C(\[H])C2=C(OC([H])([H])[H])C([H])=C([H])N2[H])=C([H])C([H])=C1F)N([H])[H]
[H]ON([H])C(=O)[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/C1=NC([H])=C([H])S1)C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(Br)=C1[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)C(\C#N)=C(/[H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C([H])=C2N=C(OC([H])([H])[H])N=C(O[H])C2=C1[H])C(=O)O[H]
[H]OC(=O)C([H])([H])C1=C([H])C(I)=C(OC2=C([H])C([H])=C(O[H])C(I)=C2[H])C(I)=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C1=NC(=NO1)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N([H])C1=NC(=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(N([H])[H])=C(C([H])=C1C([H])([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C(=O)C([H])([H])Br
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=O)C(O[H])=C(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C2=C1N(C1=C2C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]N1C2=NC3=C(N2C([H])=C1C([H])([H])[H])C(=O)N([H])C(=O)N3C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C(=O)C2=C([H])C3=C(C([H])=C2[H])C2(OC3=O)C3=C(OC4=C2C([H])=C([H])C(=C4[H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C3[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C2[H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1N=C(N(C1=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C(=O)C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]N1C2=C(C([H])=C([H])C(OC([H])([H])C([H])([H])OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])(C(=O)OC([H])([H])[H])C(=O)OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H]
[H]N1N=C(C(=C1C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N([H])C1=C(OC([H])([H])[H])N=C(C([H])=N1)C([H])([H])[H])C([H])([H])[H]
[H]OC1(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1Br
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(OC([H])([H])[H])C([H])=C2C(N(C(=O)C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1OC([H])([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)N(C([H])([H])OC(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H])S2(=O)=O
[H]C1=C([H])C(=C([H])C([H])=C1Cl)S(=O)(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])C1([H])[H]
[H]OC1=C(C(=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C(=O)N3[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([C@@]1([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])[C@@]4(O[C@]5([H])N6[C@@]([H])(O[C@]55C([H])([H])C([H])([H])[C@@]7(O[H])[C@]8([H])N(C([H])([H])C9([H])C([H])([H])C9([H])[H])C([H])([H])C([H])([H])[C@@]77C9=C(C([H])=C([H])C(O[H])=C9O[C@@]57[H])C8([H])[H])C([H])([H])O[C@@]46[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC(=NC(=N1)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])N1C1=C([H])C([H])=C([H])C([H])=C1C#N)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C(\O[H])=C1\C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])N([H])C(=O)C([H])([H])[C@@]1([H])ON=C(C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[C@]([H])(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)P(=O)(O[H])O[H])C([H])([H])C1=C([H])C2=C(C([H])=C1[H])C1=C(O2)C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])[C@@]2([H])[C@]([H])(C([H])([H])OC([H])([H])C([H])([H])[H])[C@@]2(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C1([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C(C#N)C([H])=NC2=C1C([H])=C(OC([H])([H])[H])C(OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])=C2[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C([H])([H])[H])C(=O)C1=NOC(=N1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]C1=C([H])C(C#N)=C(C([H])=C1O[C@@]1([H])C(=O)OC([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
CNC(=O)[C@@H](CC1=CC=C(OC)C=C1)NC(=O)C(CC(C)C)CP(O)(=O)CC1=CC=C(C=C1)C1=CC=CC=C1
[H]N1N=C([H])C2=C([H])C(=C([H])C(=C12)C([H])([H])[H])C([H])([H])[C@@]([H])(OC(=O)N1C([H])([H])C([H])([H])C([H])(C2=C([H])C3=C(N([H])C2=O)C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])SC1=NN=C(N1C([H])([H])C([H])([H])[H])C([H])([H])N1C(=O)C([H])([H])OC2=C([H])C([H])=C(C([H])=C12)[N+]([O-])=O
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]OC(=O)[C@@]12C([H])([H])C([H])([H])[C@@](C3=C([H])C([H])=C(C([H])=C3[H])C3=NC(C(=O)N([H])[H])=C(N=C3C([H])([H])[H])C([H])([H])[H])(C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N=C(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=[N+](C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])[C@]3(N(C(=O)[C@@]([H])(N([H])C3=O)C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C(=O)C([H])([H])OC1=C2C(=NC([H])=NC2=C([H])C([H])=C1[H])N([H])C1=C([H])C(Cl)=C(OC([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2[C@@]([H])(N([H])C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H])[N+]([O-])=O
[H]C1=C([H])C(OS(=O)(=O)C(F)(F)F)=C(C(OS(=O)(=O)C(F)(F)F)=C1[H])C1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1[H]
[H]C1=C([H])C(SC2=C(Cl)N=C(N=C2N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H])=C([H])C([H])=C1Cl
[H]C1=C([H])C(=C([H])C([H])=C1Br)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=NN1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])S(=O)(=O)C([H])([H])C(F)(F)F)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@]([H])(C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])N([C@]([H])(C4=C([H])C([H])=C(C([H])=C4[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1N([H])C(=O)C([H])([H])[H])C(=O)N([H])C1=NC([H])=C(S1)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C([H])=C1C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C(=O)O[C@@]1(C([H])([H])[H])C([H])([H])C(F)(F)F)S(=O)(=O)C([H])([H])[H]
[H]N1C2=C([H])C(=C([H])C([H])=C2OC([H])([H])C1=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
OB(O)C1=CC=CC=C1
[H]C1=C([H])C([H])=C(C#N)C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])[C@](C2=O)(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
CCCCCCCCCC[Si](C)(C)CCC(=O)NC(CC1=CC=C(C)C=C1)C1=CC=CC=C1
[H]C1=NC(=C([H])C([H])=C1[H])C1=NN(N=N1)C1=C([H])C([H])=C([H])C(=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C([H])([H])C1=C([H])C(=NO1)C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=NC2=C([H])C(Cl)=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N(C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H])C([H])([H])C(=O)O[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1F
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C(=C2[H])C1=C(N(N(C1=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2N=C([H])C([H])=NC2=C1[H]
[H]O[C@]([H])([C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])OC(=O)N([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC2=C(O1)C([H])=C([H])C(Cl)=C2[H]
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[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])=C1[H]
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[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C2=C(N=C([H])C([H])=N2)C([H])=C1[H]
NC(=O)C1=C(NC(=C1)C1=CC=NC(N)=C1)C1=CC=CC=C1
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H][C@]12CCC[C@]1(C[C@@H](C2)NC1CCSCC1)C(=O)N1CCC2=C(C1)C=C(C=N2)C(F)(F)F
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[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC([H])([H])C1=NC(I)=C(OC([H])([H])C([H])([H])OC2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C(=C1[H])N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C(Cl)(Cl)Cl)C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])[N+]([O-])=O)C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C#CC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C#CC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]O[C@]1([H])C2=C(C(C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)=C(N=C2C([H])([H])[C@]2(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(O[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C(N([H])C2=NC([H])=C3C([H])=C(C(=O)N(C3=N2)C([H])([H])[H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)=C1[H]
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC3=C(N2C([H])([H])C#CC([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C(Cl)C([H])=C1Cl)C(=O)N([H])C1=C([H])C(=C(SC2=NC3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NN2C(=NC([H])=C2C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C(F)C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@@]2([H])OC([H])([H])[H]
[H]OC1=C([H])C(C#N)=C(C([H])=C1[H])C1=NOC2=C([H])C(O[H])=C([H])C([H])=C12
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C(=O)N([H])C([H])([H])[H]
[H]OC1=C(C(=O)N([H])C([H])([H])[C@]2([H])N(C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1(N([H])C(=O)C2=C([H])C(OC([H])([H])[H])=NO2)C([H])([H])C1([H])[H])[C@@]([H])(C1=NC([H])=C(C([H])=C1F)C1=C([H])C(Cl)=C([H])C(Cl)=C1OC([H])([H])C([H])(F)F)C([H])([H])[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])S1)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])N(C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1C([H])([H])N([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=NC(=O)C1=C(OC(=N1)C1=C([H])C(F)=C([H])C(F)=C1[H])C([H])([H])[H])N([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C([H])([H])C(=O)N1C([H])([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N([H])C1=NC(N([H])C2=C([H])C(Br)=C([H])C([H])=C2[H])=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C2=N1
[H]C1=C(C(=NN1C([H])([H])C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=N2)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1C1=C(C(=NO1)C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC(=NC(=N2)N([H])[H])C([H])([H])[H])=C1[H]
[H]N([H])C1=C([H])C(=C([H])N2N=C(N=C12)C1=C([H])C([H])=C(Br)O1)C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C2C(=NC3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N(C1=C([H])C([H])=C(Cl)C(=C1Cl)C([H])([H])OC1=C2N=C(C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])[H])=C(C(=O)N([H])C([H])([H])C2=C3C([H])=C(Cl)C([H])=C([H])C3=C([H])C([H])=C2C([H])([H])[H])C2=C1[C@]1(C(O2)=C([H])C(O[H])=C(C(=O)C([H])([H])[H])C1=O)C([H])([H])[H]
[H]C1=NC(C2=C3N=C(C([H])=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2O[C@@]([H])(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])[C@]([H])(SC2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C(\[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=NC(=C([H])S1)C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2[H])C(OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)C(=O)N2C([H])([H])C([H])([H])I
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])(C([H])([H])C(=O)N1C([H])([H])SC([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C2([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC2=C([H])C([H])=C(C([H])=C12)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(N([H])C2=C([H])C([H])=C3C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4C3=O)=C2[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=NN=NN1C1=C([H])C([H])=C([H])C(Cl)=C1Cl)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C2=NN=C(S2)C2=C([H])C(C#N)=C(OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])=C([H])C([H])=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C1=NS(=O)(=O)C2=C([H])C(F)=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(Cl)C2=C(C([H])=C([H])C([H])=C2[H])C(=O)O1)N([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])O[C@]1([H])C#CC#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(N([H])C(=C2/C(=O)N([H])C3=C([H])C(=C([H])C([H])=C23)C(=O)OC([H])([H])[H])\C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=NC(N([H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])=C([H])C(=N1)N1C([H])([H])C([H])(N([H])C([H])([H])[H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C1([H])[H])[C@]([H])(N([H])C(=O)[C@@]1([H])N2C(=O)C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H]
[H]N(C1=NOC2=C(C3=C([H])C4=C(C([H])=C3[H])C3(C(=O)N4[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(=C([H])C([H])=C12)C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(=O)N([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(N2N=C([H])C(OC([H])([H])C3=C([H])C([H])=C(F)C(F)=C3F)=C(Br)C2=O)C(Cl)=C1[H]
[H]O[C@]([H])(C(\[H])=C(/[H])C1=C(SC(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])C4=C(C5=C(C([H])=C([H])C([H])=C5[H])N4C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[C@@]([H])(C([O-])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])N([H])[H]
[H]N([H])C(=O)C1=C(N([H])[H])C(=C([H])C(=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(SC([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])[N+]([O-])=O)=NN=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]C1=NC(=NC2=NC(=C([H])C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
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[H]OC1=C([H])C([H])=C2C(O[C@@]([H])(O[H])C([H])([H])N([H])C3([H])C([H])([H])C([H])([H])N(C4=C([H])C([H])=C(C([H])=C4[H])C([H])([H])[C@]4([H])SC(=O)N([H])C4=O)C([H])([H])C3([H])[H])=C([H])C([H])=C([H])C2=N1
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(C1=C(O[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OP(=O)(O[H])O[H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C(=O)O[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)O[H]
[H]C1=C([H])C2=C(C([H])=C(N=C2N1C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C([H])N1[H]
[H]N(C1=NC2=C([H])N=C(N=C2N1C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]C1=C([H])C(F)=C([H])C2=C1[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[C@]2([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=O)OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2SC3=C([H])C([H])=C([H])N=C3C2=NC([H])=N1
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])[C@]1([H])C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]O[C@]([H])(C1=NN=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2O[C@@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@@]4([H])C([H])([H])N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]34C2=C1[H]
[H]C1=C(N(C(=C1C([H])([H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
OC1=CC(Cl)=C(C=C1)C1=C(C=C(S1)C1=CC=C(O)C=C1Cl)C1=CC=C(O)C=C1Cl
[H]N(C(=O)C1=C(N([H])C([H])=N1)C([H])([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])[C@]([H])(N(C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2SC1([H])[H]
[H]N([H])C1=C(N=C(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)N([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=NN(C(=O)N(C([H])([H])[H])C([H])([H])[H])C(SC([H])([H])[H])=N1
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=NC(=C([H])C([H])=N2)C2=C([H])N=C(N2C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@]1([H])C2=C([H])C(OC(=O)N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]C#CC1=C([H])C(N([H])C2=NC3=C(C([H])=C([H])C(=C3[H])C([O-])=O)C3=C2N=C([H])N=C3[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C(F)(F)F)C1=C([H])C([H])=C([H])N=C1N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])[C@]2([H])O[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C1=NC(=C([H])O1)C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(N2C(=S)SC3=C(N=C(N=C23)C([H])([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(Br)=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C(=O)C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])N(C([H])([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C(N([H])C1=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[C@@]3([H])OC([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H])C([H])([H])[H])C2([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C(OC(=O)N(C(=O)O[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=C(S1)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])[H])C(F)(F)F)C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1OC1=NC(OC2=C([H])C([H])=C([H])C(=C2[H])C(=N[H])N([H])[H])=C(F)C(N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1(N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])=C(C3=NC([H])=C([H])C([H])=N3)C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]1(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(N([H])[H])N(N=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C(=O)N1\C(=N\N([H])C([H])([H])C(=O)O[H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
C[N]1=CC=C(C=C1)C1=C2\C=CC(=N2)\C(=C2/N\C(\C=C2)=C(/C2=N/C(/C=C2)=C(\C2=CC=C\1N2)C1=CC=[N](C)C=C1)C1=CC=[N](C)C=C1)\C1=CC=[N](C)C=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)C2=C([N+]([O-])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(F)C([H])(OC2=C([H])C([H])=C([H])C3=C([H])C([H])=C(N=C23)C2=NN=C3C([H])=C([H])C([N+]#[C-])=C([H])N23)C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CN([C@H]1CN(C[C@@H]1C1=CC=CC=C1)C(=O)N1CCN(CC1)S(C)(=O)=O)C(=O)C(C)(C)C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F
[H]OC(=O)C([H])([H])N1C(SC([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])[H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C1=NN(C(=O)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C(=O)C(OC([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])=C([H])C1=O
[H]N1C(=NC(C2=C([H])C([H])=C(F)C([H])=C2[H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C3=C4C(N([H])S2(=O)=O)=C([H])C([H])=C([H])C4=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]C1=C(C2=C(N=C(N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N(C2=O)C([H])([H])[H])N1C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)O[H])C1=C([H])C(C2=NC3=C([H])C(=C([H])C([H])=C3N2[H])C(=N[H])N([H])[H])=C(O[H])C(=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])[H]
[H]C1=NC2=C(C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])N=C23)C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=NC(O[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]1(OC2=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC3=C(C([H])=C(OC4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=NN2C(=N1)C1=C(N=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N([H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=NC3=C(C([H])=N2)C([H])([H])C([H])([H])C2=C3C([H])=C([H])C(N([H])C(=O)C([H])([H])C(=O)OC([H])([H])[H])=C2[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])C([H])([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])C([H])([H])N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])[C@]([H])(N2C4=C(N=C2C([H])([H])[H])C([H])=C([H])C([H])=C4[H])C3([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=N1
[H]OC(=O)[C@]([H])(SC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(OC([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C(S1)N(C(=O)N(C2=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C(=O)N1N=C([H])C([H])([H])[C@]1([H])C#N)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2C([H])=C([H])C(=NN12)N([H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(C([H])=C(\C([H])=C(/[H])N2C([H])=NC([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])OC2=C(C([H])=C(\C([H])=C(/[H])C3=C([H])C(O[H])=C([H])C(O[H])=C3[H])C([H])=C2[H])[C@]1([H])C1=C([H])C(O[H])=C([H])C(O[H])=C1[H]
[H]O[C@]([H])([C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])P(=O)(OC([H])([H])[H])OC([H])([H])[H]
[H]OC1=C([H])C(=C([H])N=C1[H])N1C([H])([H])[C@]2([H])C([H])([H])N([H])C([H])([H])[C@]2([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)N([H])C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(C([H])=N1)C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])OC(=N2)C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]N(C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(\N=C(/[H])C1=C([H])C(Br)=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C(=S)N([H])C([H])([H])[H]
[H]OC(=O)C1=C(N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@](C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C2=NC([H])=C(C([H])=C2C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=N1)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(SC2=C(C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C(F)(F)F
[H]N1C([H])([H])C2=C(N(C([H])=C2C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])C(OC([H])([H])[H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N(C(=O)C([H])([H])N([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H]
[H]OC(=O)[C@]([H])(OC1=C(I)C([H])=C(C([H])=C1I)C1=C2C(OC(=C2C([H])([H])[H])C([H])([H])[H])=C([H])C2=C1C1=C(S2)C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C([H])C2=C1N=C(N1N=C(N=C21)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(C2=N[N-]N=N2)(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C(=C(O[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])O[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC(Cl)=C1C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]N([H])C([H])([H])C([H])([H])N1C([H])=C(C2=C([H])C([H])=C([H])N=C12)S(=O)(=O)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@]2(O[H])C(=O)C([H])([H])SC2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C4=C(C([H])=NN4C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]12[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C1=NC3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3C(=O)N1C([H])([H])C2([H])[H]
[H]C1=C(SC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H])C(=O)C(F)(F)F
[H]C1=C(C(=C([H])C(=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])N([H])C([H])([H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])S(=O)(=O)C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(OC3=NC([H])=NC(=C3[H])C3=C(N([H])C(=O)C4=C([H])C([H])=C([H])C([H])=N4)C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])=C([H])C([H])=C2S1
[H]N([H])C1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])OC1=C(OP(=O)(O[H])O[H])C(OP(=O)(O[H])O[H])=C(OP(=O)(O[H])O[H])C([H])=C1[H]
[H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C2[H]
[H]C1=NC(C2=C3N=C(C([H])=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C2=C(S1)S(=O)(=O)N(C(=C2[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])=C([H])[H]
[H]OC(=O)C(\[H])=C(\C(\[H])=C(/[H])\C(\[H])=C(/C1=C([H])C(=C([H])C(=C1OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])/C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C(C([H])=C([H])C(Cl)=C1[H])C(=O)N([H])C([H])([H])C1=C(F)C([H])=C(I)C([H])=C1F
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(N1N=NC(=N1)N1N=C([H])C([H])=N1)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
COC1=CC=CC(NC2=C3N=CN(C4O[C@H](CO)[C@@H](O)[C@H]4O)C3=NC=N2)=C1
[H]O[P@](=O)(C([H])([H])[H])[C@]([H])(C(=O)N([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(\N=N\[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N=C([H])N1[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(O[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C([H])([H])P(=O)(O[H])O[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C(C([H])=NC2=C1C([H])=NN2C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])N(C([H])([H])[H])C([H])([H])C(=O)N([H])C1=C(C([H])=C(C(Cl)=C1[H])S(=O)(=O)N([H])[H])S(=O)(=O)N([H])[H]
[H]C1=NC(C#CC2=C([H])C3=C(C([H])=C2[H])N(C2=C([H])C([H])=C([H])C([H])=C2C3=O)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N1C2=C(N=C1C(F)(F)F)C(=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])Cl)C1=C([H])C([H])=C(SC2=C(C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=NN=NN1C(SC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=N2
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(SC#N)C([H])=C1[H]
[H]N1C([H])=C(N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]C1=C([H])C([H])=C(S1)C1=NN=C(SC([H])([H])C([H])([H])OC2=C([H])C([H])=C(Cl)C([H])=C2[H])N1C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=NC(C2=NC(=C([H])S2)C([H])([H])[H])=C(N1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
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[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(O2)[C@@]2([H])N(C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N([H])C([H])([H])[C@]1([H])N(C([H])([H])C2=C(Cl)C([H])=NC([H])=C2Cl)C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C(Cl)C([H])=NC([H])=C1Cl)C([H])([H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@]([H])(OC1=C([H])C([H])=C([H])C(C#N)=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C23)S(=O)(=O)C2=C([H])C([H])=C([H])S2)C1([H])[H]
[H]C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C(=O)N1C([H])([H])SC([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C1([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(N2C([H])=C(C(=O)N([H])[H])C(=O)C3=C([H])C([H])=C(C([H])=C23)C2=C(Cl)C([H])=NC([H])=C2[H])C(Cl)=C1[H]
[H]N(C(=O)C1(N([H])C(=O)C2=C([H])N=C([H])C([H])=N2)C([H])([H])C1([H])[H])[C@@]([H])(C1=C(F)C([H])=C(C([H])=C1[H])N1N=C(Cl)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=S)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C(Br)=C(OC2=C([H])C([H])=C(O[H])C(=C2[H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(Br)=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]3([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])O[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])(F)F)C(F)(F)F)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1=C([H])N=C(N2C([H])([H])C([H])([H])N([C@@]([H])(C([H])([H])C([H])([H])[H])C2([H])[H])C2([H])C([H])([H])C([H])([H])N(C(=O)C3=C(N=C(Cl)C([H])=C3[H])N([H])[H])C([H])([H])C2([H])[H])C(Cl)=N1
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N(C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=NC(=C([H])C([H])=N2)C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C(OC([H])([H])[H])=C(Cl)C(=C2[H])C([H])([H])[H])C2=C1C(=O)C1=C(O[H])C(=C(C([H])=C1C2=O)C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N=C1O[H]
[H]OC(=O)[C@@]12C([H])([H])C([H])([H])[C@@]3(C(=C([H])C([H])([H])[C@]4([H])[C@@]5(C([H])([H])[H])C([H])([H])C6=C(N([H])C7=C6C([H])=C([H])C([H])=C7[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]5([H])C([H])([H])C([H])([H])[C@@]34C([H])([H])[H])[C@]1([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[C@]([H])(N([H])C(=O)C([H])([H])C1=C(Cl)C([H])=C([H])C(N([H])C([H])([H])C(F)(F)C2=NC([H])=C([H])C([H])=C2[H])=[N+]1[O-])C([H])([H])[H]
[H]N1N=C([H])C2=C(C([H])=C([H])C(Cl)=C12)C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=NC([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])S(=O)(=O)C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C([H])=C([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]OC(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C(=C1SC(=O)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N2C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1[H])C1=NOC(=C1C1=C([H])SC(=N1)C([H])([H])[H])C(F)(F)F
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C(C([H])=C([H])C(F)=C2[H])[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=NC2=C([H])C([H])=C([H])C([H])=C12)C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C#N)C([H])([H])C([H])([H])N1C(=O)N(C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@](C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C2N(C([H])=C([H])N=C2N([H])[H])C(=N1)C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=NOC([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C(=O)N(C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])N([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2(SC([H])([H])C([H])([H])S2)C1([H])[H]
[H]N(\N=C1/C(=O)N([H])N=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C(=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C(=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(N=C=S)C([H])=C2C(C(=O)C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(N(C(=N1)N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C(C#N)=C1[H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC([H])([H])[C@@]1([H])O[C@]([H])(N2C([H])=C(\C([H])=C(/[H])C([H])([H])N([H])[H])C(=O)N([H])C2=O)C([H])([H])[C@]1([H])O[H]
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[H]OC(C1=C([H])C(Cl)=C(C([H])=C1[H])N(C([H])([H])C1=C(OC(=N1)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
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[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H])C(F)(F)F
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[H]N([H])C1=NC([H])=NC(OC2=C([H])C(Cl)=C(N([H])C(=O)N([H])C3=C([H])N=C([H])C([H])=C3[H])C([H])=C2[H])=C1\C([H])=N\OC([H])([H])[H]
[H]N(C(=O)C1=C(Cl)C([H])=C2N([H])C(=O)C(=C(OC([H])([H])C([H])([H])[C@@]3([H])N([H])C([H])([H])C3([H])[H])C2=C1[H])C1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=N1
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N([H])C1=C(O[C@]([H])(C2=C(Cl)C([H])=C([H])C(F)=C2Cl)C([H])([H])[H])C([H])=C(C([H])=N1)C1=C([H])N(N=C1[H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([C@@]1([H])C(=O)N(C2=C(F)C([H])=C(C([H])=C2[H])N2C([H])=C([H])N=C2C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C(Cl)C([H])=C([H])C2=C1[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])OC([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C(F)(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C(N2N=C([H])C(=C2N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])OC1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1N([H])S(=O)(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1\C(=N/C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])N(C2=C(OC([H])([H])C([H])([H])[H])C([H])=C(Cl)C([H])=C12)C([H])([H])[H])C1=NN=NN1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=NN1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C(=O)N(C([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=C([H])C([H])=NN2C1=NC(=C2C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])N=C1[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])C([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])O[H]
[H]N1N=C2N(C1=O)C(=NC1=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C21)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C2=C1N(C(=N2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1
[H]OC(=O)C1=C([H])C(\N=C2/SC(=NN2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C2O[C@@]([H])(N([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C(=O)N(C1=C([H])C([H])=C(Cl)C(=C1Cl)C([H])([H])OC1=C2N=C(C([H])=C(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=N\C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N2C(=O)[C@@]([H])(C3=C([H])C([H])=C4N=C(C([H])=C([H])C4=C3[H])C(F)(F)F)C([H])([H])C([H])([H])[C@@]2(SC1([H])[H])C([H])([H])[H])C(=O)C1=NC([H])=C([H])S1)\[N+]([H])([H])[H]
[H]OC1=C(C(=C2N=C(SC2=C1C([H])([H])[H])N([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N([C@@]1([H])[C@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N([H])C(=O)C1=C(N([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2O1
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C(SC([H])=C1[H])N([H])C(=O)C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1N([H])C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(OC([H])([H])[H])C(=O)C1=C([H])C([H])=C(C(N([H])C2=NC(=NC(N(C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C2C#N)N([H])C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)N([H])[C@]2([H])C([H])([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])[C@@]2([H])C([H])([H])C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H]
CC1=CC(NC2=NC(NCC3=CC(=NO3)C(N)=O)=NC=C2)=NN1
[H]OC([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=NC(=N2)N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])OC3([H])[H])N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])OC3([H])[H])C([H])=C1[H]
[H]\C(=C(/[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C(=O)C(F)(F)F)C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C(=O)C([H])([H])[H])C1=C([H])C(Br)=C(OC(=O)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C1=NC([H])=NC([H])=C1[H])C1=NC(=NC2=C1N(N=C2C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C(F)(F)F)N1C([H])([H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1N=C(N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C(=O)C(Cl)=C(Cl)C1=O
[H]OC([H])([H])[C@]([H])(N([H])C1=C([H])C(=NC2=C(C(=O)N([H])[H])C(=NN12)N([H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C3=C(Cl)C([H])=NC(=C3[H])N3C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])N(N=C4[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C21)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C(SC([H])([H])C2=C([H])C(=C([H])C([H])=C2OC([H])([H])[H])C(=O)C([H])([H])[H])=NC2=C([H])C(=C([H])C([H])=C12)C(F)(F)F
[H]C1=C(N=NN1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OS(=O)(=O)C1=C(N([H])[H])C2=C(C(=O)C3=C([H])C([H])=C([H])C([H])=C3C2=O)C(N([H])C2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N(C1=C([H])C(=O)OC2=C([H])C([H])=C(Cl)C([H])=C12)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3N([H])C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
[H]O\N=C(/[H])C1=NN2C(=N1)C1=C([H])C([H])=C([H])C([H])=C1N=C2SC([H])([H])C#N
[H]O[C@@]([H])(C([H])([H])N(C1=C([H])C(OC2=C(C([H])=C([H])C([H])=C2[H])[N+]([O-])=O)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC(F)(F)C([H])(F)F)=C1[H])C(F)(F)F
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1N=C(C2=C([H])C([H])=C3OC([H])=C([H])C3=C12)C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])[C@@]([H])(C([H])([H])OP(=O)(OC([H])([H])[H])OC([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])N1C(=NC(=C1C(=O)C([H])([H])C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(S[C@]([H])(C2=C(N=C(S2)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])[H])C([H])([H])C2=C(F)C(F)=C(F)C(F)=C2F)C([H])=C1C([H])([H])[H]
[H]OC1=C(Cl)C([H])=C(\C([H])=C2/S\C(=N/C([H])(C([H])([H])[H])C([H])([H])[H])N(C2=O)C2=C([H])C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OP(=O)(O[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C(C(=O)N([H])[C@@]([H])(C1=NN=NN1C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N([H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C1=NN2C(=NC(=C2C([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C4=C(C([H])=C3[H])N(C([H])=C4[H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C2=C1[H]
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[H]OC(=O)C([H])([H])[C@]1([H])N([H])C2=C(C([H])=C(C([H])=C2[H])C(=O)N([H])C([H])([H])C([H])([H])N([H])C2=NC([H])=C([H])C([H])=N2)C([H])([H])N(C1=O)C([H])([H])[H]
Cl[H].[H][C@]12CNC[C@]1([H])C1=CC=C(C)C(Cl)=C1C(=O)N2
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])C(=O)[C@]([H])(C1=NN=C2N1C([H])=C(N=C2C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(OC2=NC(OC3=C([H])C([H])=C([H])C(=C3[H])C(=N[H])N([H])[H])=C([H])C([H])=C2[H])C([H])=C1[H]