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[H]N1C([H])([H])C([H])([H])N(C2=C([H])N=C([H])C(OC([H])([H])C([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1(C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C2C(=NN1[H])C1=C([H])C([H])=C([H])C([H])=C1OC2([H])[H]
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[H]C1=C([H])C(=C([H])C([H])=C1C#N)C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]N=C1N2C([H])=C([H])C3=C(C([H])=C([H])C([H])=C3[H])C2=NC(SC([H])([H])[H])=C1S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(OC3=C(C([H])=C([H])C(F)=C3[H])C([H])([H])[H])N(C3=C([H])C([H])=C([H])C([H])=C23)[C@@]2([H])C([H])=C([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])=C4C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=NC2=C(S1)C([H])=C([H])C(=C2[H])S(=O)(=O)C([H])([H])[H]
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[H]N(C(=O)C1=C(N([H])C2=C([H])N=C([H])N=C2[H])C([H])=C([H])C(=N1)C1([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])N=C1[H])C(=O)N([H])C([H])([H])[H]
[H]N(C1=NC(=C(N=C1C([H])([H])C([H])([H])[H])N([H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=N1
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])N(N=C1C1=C([H])C([H])=C([H])S1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(C#N)(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C2C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C([H])([H])C([H])(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
COC1=C(OC)C=C(CC(OC(=O)\C=C\C2=CC=C(Br)C=C2)C(=O)NO)C=C1
[H]N1N=NC(=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])OC1=C([H])C([H])=C(\C([H])=C(/[H])C2=NC3=C([H])C(Cl)=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=NC(=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
NC1=C(C=CC(NCCNC2=NC=C(C3=NC=CN3)C(=N2)C2=C(Cl)C=C(Cl)C=C2)=N1)N(O)=O
[H]C1=C([H])C2=NC(=C([H])C([H])=C2C(=C1[H])C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C([H])[C@]4([H])OC(=N[C@]4([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]C1=C(Cl)C(=C([H])C(Cl)=C1SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])O[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])O[H]
CCC1=NC(C(N)=O)=C2CN(CCC2=N1)C(=O)CCC1=CC=C(OC(F)(F)F)C=C1
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C([H])C([H])=C(C([H])=C1C(=O)C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C(=N1)N1C([H])([H])C([H])([H])O[C@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C1([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C2=C(SC3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C23)C(=O)N([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N([H])[C@]1([H])C([H])([H])N(C2=C(C#N)C3=C(N2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])C2=NC([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C1([H])[H]
[H]N(N([H])C(=O)C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])[H])C([S-])=S
[H]O[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)C2=C1C([H])=C([H])C(=C2[H])C(=O)N([H])C([H])([H])[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]OC1=NC(=C(N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(C#N)C([H])=C1[H]
[H]N1C(=O)N(C2=C1C([H])=C(C([H])=C2[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]12[H])C([H])([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])C(=O)C([H])=C1[H])C1=C([H])C([H])=C2N=C([H])SC2=C1[H]
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2Cl)C(=O)N([H])C2=NC(=C(S2)C([H])([H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C(F)C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(N([H])C2=NC(=NC3=C(C#N)C([H])=NN23)N([H])C2=C([H])C(N([H])C(=O)C([H])([H])[H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])N=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=NC(OC([H])([H])[H])=NC([H])=C1C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C([H])=C2N([H])C(=O)C([H])([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N1C(=NC2=C(Br)C(Br)=C(Br)C(Br)=C12)N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N1C(=O)C(=NC([H])=C1C([H])([H])C([H])([H])[H])N([H])C([H])([H])C1=NC2=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N2[H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C([H])([H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C2=NC(Cl)=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]12C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C3=C([H])C([H])=C([H])C(I)=C3[H])[C@]3([H])OC4=C5C(=C([H])C([H])=C4OC([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])[C@@]235
COC1=CC=CC=C1\C=C(/C#N)C(=O)NC1=CC=C(C=C1)S(N)(=O)=O
[H]C1=C([H])C(=C([H])C2=C1OC(=N2)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=O)C([H])=C1[H])[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC([H])([H])[C@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]([H])(N(C2=C3C([H])=C([H])N([H])C3=NC([H])=N2)C([H])([H])[H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)C1=C2C(SC3=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=NC([H])=N1
[H]OC([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C2=C1N(C([H])=C(C(=O)N([H])C1=C([H])C([H])=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C(=C1[H])C(F)(F)F)C2=O)C([H])([H])[H]
[H]C1=C([H])C2=NC([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])[N+]([O-])=O
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(=O)N(C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@](O[H])(C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C(=O)C([H])([H])\C([H])=C([H])\[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
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[H]OC1=C([H])C([H])=C([H])C2=C(OC(=O)C(\[H])=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C12
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[H]C1=C([H])C(=C(S1)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
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[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])SC([H])([H])C([H])([H])N1C(=O)C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1F)C([H])(C([H])([H])[H])C([H])([H])[H]
CN(C1=NC=CC=C1CNC1=C2C=CNC2=NC=C1C)S(C)(=O)=O
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[H]N(C1=NC(=C([H])C2=C1C(=O)N([H])C([H])=C2[H])C1=C([H])N=C([H])C(OC([H])([H])[H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(O1)C([H])([H])[H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C2N=C(C([H])=NC2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(OC([H])([H])C([H])([H])C1=C([H])N([H])C3=C1C([H])=C([H])C([H])=C3[H])N=C2N([H])[H]
[H]N(\C(=N/C#N)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C([H])C(Cl)=C(O1)C1=NC(=NO1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
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[H]OC1=C([H])C(C([H])=C([H])[H])=C2OC(=NC2=C1[H])C1=C(F)C([H])=C(O[H])C(F)=C1[H]
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[H]N([H])C(=O)C1=C([H])C(=NN=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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COC1=CC=C(C=C1)N(C)C(=O)CN1C(=O)OC2=CC=C(C=C12)C1=CC=CC=C1
FC1=CC=CC=C1C(=O)CC1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
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[H]N1N=C2C3=C([H])C([H])=C([H])C([H])=C3C(=O)[C@@]3([H])C([H])=C([H])C([H])=C1[C@@]23[H]
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[H]C([H])=C([H])C([H])([H])N(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)[C@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C2=C(C(=NN2C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])C1=C([H])C(F)=C(C(F)=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(Cl)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@@]3([H])C([H])([H])[C@]1([H])C([H])([H])[C@](C3([H])[H])(C2([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C2O[C@@]([H])(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])[C@]([H])(SC2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C(=C(F)C([H])=C2[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C([H])=C2N1[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])OC([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NN=C(O1)SC([H])([H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]N(C1=C([H])N=C([H])C(=N1)C1=C([H])C(N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])N=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C(C(SC3=C([H])C4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])=C(S2)C([H])([H])[H])C(=O)N1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C2=NC3=C(N2[H])C([H])=C(Cl)C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@@]([H])(OC(=S)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C(=O)[C@]([H])(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
CN1N=C(C)C(C(=O)N2CCCCC2C2=CC=CN=C2)=C1OC1=CC=C(Cl)C=C1Cl
[H]N([H])C1=NC2=C(N=C([H])N2C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C(Cl)=N1
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])[C@@]([H])(OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1N=C(OC1=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=C([H])C(F)=C3[H])N3C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])N(C1=C([H])C(=NC(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])C1=NC([H])=C([H])C([H])=N1)N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC(=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]O\C(OC([H])([H])C([H])([H])[H])=C1\C(=NC(=C(C(=O)OC([H])([H])C([H])([H])SC([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
Cl[H].CCCCCCCNC1=C2CCCCC2=NC2=CC=C(OC)C=C12
[H]C1=C([H])N2C(=NC(=C2C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C(F)(F)F
[H]C1=C(SC2=C1N=C1N(C2=O)C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
OC(=O)C1=NN=C(C=C1)N1CCC2(CC1)CCN(CC1=CC(=CC=C1)C(F)(F)F)C1=C(O2)C=CC=C1
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1F)N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])SC1=NN([H])C(O[H])=N1
[H]N(C(=O)C1=C([H])C(=C([H])C(N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(F)=C([H])C([H])=C1C(=O)N1C([H])([H])C([H])([H])C(=C([H])C(=O)N([H])[C@@]2([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C4C([H])=C(F)C([H])=C([H])C4=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(N=C(F)S1)C#CC1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C(=C2[H])C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C(F)=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])C1=C(C3=C(N1[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
COC1=CC2=C(C=C1)N=C(N2C1=CC=NC(NC2CCCCC2)=N1)C1=CC2=CC=CC=C2C=C1
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(SC([H])=C1[H])C([H])([H])OC1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(OC([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C(=N1)N(C([H])=C(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])=C([H])C2=NC([H])=NC(N([H])C3=C([H])C([H])=C(OC4=C([H])C5=C(C([H])=C4[H])C(=O)N([H])C5([H])[H])C(Cl)=C3[H])=C12
CC(C)(C)OC(=O)N1CCC(COCC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)(CC1)C1=CC=CC=C1
[H]OC1=C(C([H])=C([H])C2=C1[C@]13C([H])([H])C([H])([H])N(C([H])([H])C4([H])C([H])([H])C4([H])[H])[C@]([H])(C2([H])[H])[C@]1(O[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(=O)N([H])[H]
[H]N(C(=O)[C@@]1([H])N([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C(N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C([H])=C([H])C([H])=C(N([H])C3=NC([H])=C(O3)C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C2=C1[H]
[H]C1=C([H])C2=C(C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])O2
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(Cl)N=C1[H])C2([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C2SC3=C(N=C(N([H])C3=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2=C1[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])[C@@]([H])(OC([H])([H])C1=NC(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C2C([H])=NN(C2=NC(SC([H])([H])[H])=N1)C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C(=O)N([H])[C@]2(N(C(=O)N([H])C3=C([H])C([H])=C(C([H])=C23)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])C1=O
[H]N(C(=O)C1=C(N(C2=C([H])C(OC3=NC([H])=C([H])S3)=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]OC(=O)[C@]1([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C(Cl)C([H])=C2[C@]([H])(O[H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
CC1=CC(OCCCC2=C(NC3=CC(Cl)=CC=C23)C(O)=O)=CC=C1Cl
[H]C1=NN=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=N1)C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C2=C(N([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=NC2=C1SC(=C2[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@](C(=O)N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C1=NS(=O)(=O)C2=C([H])C(F)=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C(F)(F)F
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C1=NC(=C(N([H])C1=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1(C(=O)N([H])C([H])([H])C(F)(F)F)C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N([H])C1=NC(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])=C([H])C2=NC(=NN12)C1=C([H])C([H])=C(Cl)O1
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(S1)C([H])=C(C([H])=C2[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C(OC([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])\C2=C(\[H])C([H])([H])N2C([H])=NC3=C2C([H])=C(C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])OC1=C2C([H])=C([H])N(C2=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N(\C([H])=C(/[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C([H])([H])[H]
[H]N(C(=O)N([H])C1=C(C([H])=C([H])N=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C2=C(N=C([H])C([H])=C2[H])N(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])C1=NN=C2N1C([H])([H])C([H])([H])C1=C2N(N=C1C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2S1
[H]N1C([H])=C(C#N)C2=C([H])C([H])=C([H])C(C(=O)N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C4=C([H])C([H])=C(F)C([H])=C4F)C([H])([H])C3([H])[H])=C12
[H]C1=NC2=C(N1C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
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[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])N(C1=C(C(=NC(=N1)C([H])([H])[H])C(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])=C([H])[H]
[H]N1C([H])=C(N=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C2C3=C(C([H])=C([H])C([H])=C3[H])C(=O)N([H])C([H])([H])C2=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C#N)C(=C1[H])C(=O)C([H])([H])[H]
[H]N([H])C1=C2C(SC([H])=C2C2=C([H])C([H])=C(N([H])C(=O)C3=C([H])C4=C(C([H])=C([H])C([H])=C4[H])N3C([H])([H])[H])C(OC([H])([H])[H])=C2[H])=C([H])C([H])=N1
[H]N1C([H])=C([H])C([H])=C2C([H])=C(N=C12)C([H])([H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1(C2=C([H])C([H])=C(F)C([H])=N2)C([H])([H])C([H])([H])N(C2=NC(=C3C([H])=C(N([H])C(=O)C([H])([H])OC4=C([H])C([H])=C(OC(F)(F)F)C([H])=C4[H])C([H])=C([H])C3=N2)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O\N=C(\C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])=C([H])[H])C([H])=C1[H])/C([H])([H])[H]
[H]C1=C([H])C2=C(C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C(=O)C4=C([H])C([H])=C(Cl)C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])O2
COC1=CC=C(NC2=C(C(C)=NN2C2=C(C)C=CC=C2)C2=CC=C(C=C2)C(C)=O)C(=C1)C(O)=O
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[H]N1C(=O)N([H])[C@]2(C1=O)C1=C([H])C(F)=C([H])C([H])=C1OC([H])([H])C2([H])[H]
[H]ON([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]1([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=NC(=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(C2=C([H])C([H])=C(O2)C([H])([H])[H])=C(C(=N1)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H]
IC1=CC=C(CN2C=CN=C2)C2=C1OC1=CC=CC=C1C2=O
[H]N(C1=NN=NN1C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H]
[H]C1=C([H])C(=NC(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=NC(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(N2C3=C(N=C2C([H])([H])[H])C(=C([H])C(=N3)C([H])([H])[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(Br)=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C(N([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C(=O)C1=O)C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
CCOC(=O)C1=C2N(N=C(C=C2C2=CC=CC=C2)N2CCOCC2)C(CCO)=C1C1=NC(CCO)=NO1
[H]C1=C2C(=O)N(C(=O)C2=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2Cl)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])S1(=O)=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])C(Cl)=C([H])N2[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])[C@]1([H])C(=O)N2[C@]([H])(SC([H])([H])[C@@]2([H])C(=O)N([H])[C@@]2([H])C([H])([H])C(=O)O[C@]2([H])O[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(C(C(=O)C([H])([H])[H])=C(N1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C1=C([H])C3=C(OC([H])([H])O3)C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])\C(\[H])=C(\C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N([H])[C@]1([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])N1N=C(C([H])=C1N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C(=C1[H])C([H])([H])N([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3N=C(N([H])C3=NC([H])=C2Br)C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C([H])C2=C1[C@@]13C([H])([H])C(=O)C([H])([H])C([H])([H])[C@@]1(OC([H])([H])[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C(C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C1=NC2=C(S1)C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C3=C([H])C(=C([H])C([H])=C3[H])N3N=C([H])N=C3[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C1=C([H])C2=C(N=N1)C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])C2=O)C(F)(F)F
[H]N(N1C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])=C(Cl)C([H])=C2[H])C(=O)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C(=O)N([H])N2C3=C(N=C(N4C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C4([H])[H])C4=C2C([H])=C([H])C([H])=C4[H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C(=O)N([H])C1=NN=C(S1)S(=O)(=O)N([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2S1)[C@]([H])(C(=O)N([H])[C@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C(Br)=C(OC3([H])C([H])([H])C([H])([H])N([H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C2C([H])=C([H])C([H])=C([H])C2=N1
[H]N([H])C([H])([H])C1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C#N
[H]N(C(=O)[C@@]([H])(N1C(=O)C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1[H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N1N=C(C2=C1C([H])([H])C([H])([H])N(C(=O)C([H])([H])SC([H])([H])[H])C2([H])[H])C1=C([H])C([H])=C(C(SC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(F)C([H])([H])C2([H])[H])=C1[H])C(F)(F)F)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N=C([H])C(=N1)N([H])C([H])([H])C([H])([H])N([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C(F)=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])C(C(=O)N([H])[C@@]2([H])[C@@]3([H])C([H])([H])[C@]4([H])C([H])([H])[C@]([H])(C3([H])[H])C([H])([H])[C@@]2([H])C4([H])[H])=C1SC1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N=C(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(F)C2=C1C([H])([H])C(=O)N2[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=NC(=C([H])C([H])=C1[H])C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)C1=NSC([H])=C1N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])[C@]2([H])C([H])=NN([H])[C@]2([H])C([H])=C1[H]
[H]N(C1=NC(C2=C([H])N=C3C([H])=C([H])C(=C([H])N23)C([H])([H])[H])=C(Cl)C([H])=N1)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])N(C(=O)C1=C([H])C(O[H])=C(O[H])C([H])=C21)C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C2C(O[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=N\OC([H])([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(\C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])\C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=NN=C2N1C([H])=C([H])C1=C2C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NN([H])C(=N2)C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(O1)C1=C([H])C([H])=C([H])C([H])=C1C(=O)C2=O
[H]O[C@]1([H])[C@]([H])(O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])[C@@]2([H])C([H])([H])OC([H])([H])C2([H])[H])[C@@]1(O[H])C([H])([H])[H])C([H])([H])OC(=S)N([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C(SC2=NC(=C([H])C(=C12)C([H])([H])[H])C([H])([H])[H])C(=O)N([H])\N=C(/[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N1C(=N[C@](C2=C([H])C([H])=C(F)N=C2[H])(C2=C([H])C([H])=C(F)C([H])=C2[H])[C@]1([H])C([H])([H])[H])C1=C([H])C(=C([H])C(=O)N1[H])C([H])([H])[H]
CN(C(=O)CN1C(=O)OC2=CC=C(C=C12)C1=CC=CC(=C1)C(F)(F)F)C1=CC=CC=C1
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(N([H])S(=O)(=O)C2=C(SC([H])=C2[H])C(=O)OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)N([H])C(=O)C(OC2=C([H])C([H])=C(OC3=C([H])C([H])=C(C([H])=C3[H])C3=NC(=C([H])O3)C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])(C1=O)C([H])([H])C([H])([H])OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C2=NN(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C(O[H])=C1O[H]
[H]ON1C(=O)C2=C(N=C1C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])=C([H])C(Br)=C2[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(/C([H])([H])N1C([H])=NC([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C(=C([H])C2=C([H])C(=C([H])C([H])=C12)C([H])([H])[H])[C@@]([H])(N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=NN=NN1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)[C@]([H])(C#N)N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C(Cl)N([H])C4=C3C(=C([H])C([H])=C4[H])[C@]2([H])C1([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C1=C(O[H])C2=C(C([H])=C([H])C(=C2[H])C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])N(C1=O)C([H])([H])[H]
FC(F)(F)C1=CC=CC(SC2=NN3C(C=C2)=NN=C3C2CCCC2)=C1
[H]N(C1=NC(=NC2=NC([H])=C(C([H])=C12)C1=C([H])N(N=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]OC1=NC(=NC2=C1C([H])=C(C([H])=C2[H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])SC([H])=N1)C([H])([H])C#C[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])[C@@]1([H])C(=O)N(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(N([H])C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC2=C(C([H])=C(C(O[H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])[H])=C1C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(N([H])C([H])([H])C([H])([H])[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
[H]N1C(=NC2=C([H])N=C3C([H])=C(Br)C([H])=C([H])C3=C12)C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)O[C@]1([H])C(=O)[C@@]2([H])[C@@](C([H])([H])[H])(C([H])([H])C([H])([H])[C@@]3([H])C(=O)O[C@]([H])(C4=C([H])OC([H])=C4[H])C([H])([H])[C@]23C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C1([H])[H]
[H]N([H])C([H])([H])[C@@]12N([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(C(=O)C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])[N+]([O-])=O
[H]N([H])C1=NC2=C(C([H])=N1)C([H])=C(C(=N2)N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]OC([H])([H])C([H])([H])C([H])([H])C1=NC2=C(C(SC([H])([H])[H])=NN2C2=C(Cl)C([H])=C(Cl)C([H])=C2Cl)C(=O)N1[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=N\C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])\N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[P+](C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
COC1=CC=C(C=C1)C(=O)NC1=NC(=NC2=CN(N=C12)C1=CC=CC=C1)C1=CC=CC=C1
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C([H])C(=NC([H])=N2)C2=C(C([H])=C([H])C([H])=C2[H])C(=O)C([H])([H])[H])C([H])([H])[C@]1([H])C1=C([H])C(F)=C(F)C([H])=C1F
[H]OC1(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])OC2=C([H])C([H])=C3C(=C2[H])C([H])=C(C([H])=C3C2=C([H])OC([H])=C2[H])C2=NN(N=N2)C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(SC2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C2[H])C(=C1[H])C(F)(F)F)C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=C1C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C1=C([H])N(N=C1[H])C([H])([H])[H]
[H]C1=C(O[C@@]2([H])C([H])([H])SC([H])([H])C2([H])[H])C([H])=C2C(OC3(C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(Cl)C(=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
COC1=NC(=NC(C)=C1F)N1C[C@H]2C(=O)N(C)C(=N)N[C@]2(C1)C1=C(F)C=CC=C1F
[H]OC([H])([H])[C@@]1([H])OC(=O)\C(=C(/N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O
ONC(=O)CCCCCNC(=O)NC(=O)C1=CC=CC(=C1)N(O)=O
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C1=C([H])C(C#N)=C(C([H])=C1O[C@@]1([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
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CCNC(=O)CC#N
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[H]OC([H])([H])C1(N([H])C2=NC3=C(N([H])C([H])([H])N3C([H])(C([H])([H])[H])C([H])([H])[H])C(=N2)N([H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@@]([H])(C(\[H])=C(/[H])C2=C(C([H])=C(Cl)C([H])=C2Cl)C2=C([H])C(=C(F)C([H])=C2[H])C([H])([H])[H])C1([H])[H]
[H]OC1(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])OC2=C([H])C([H])=C3C(=C2[H])C([H])=C(C([H])=C3C2=C([H])C([H])=C([H])C([H])=C2[H])C2=NN(N=N2)C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C1C([H])=C1N=C([H])C([H])=NC1=C2[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(N([H])C2=NC([H])=NC3=C([H])C(OC([H])([H])C4([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C4([H])[H])=C([H])C([H])=C23)C([H])=C1[H]
[H]C1=C([H])C2=C(N=C(N2C([H])([H])C([H])([H])C([H])([H])O[C@@]2([H])O[C@]([H])(C3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])=N1
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)N(C2=C([H])C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(OC([H])([H])C([H])([H])OC([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(SC2=NN3C([H])=C([H])C([H])=C3C(=N2)N([H])C2=NN([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=NC3=C(N=C(N=C3N=C2[H])N([H])[H])N([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H])C(F)(F)F
[H]N1C2=C(SC3=C2C2=C(N=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])=C3[H])C(=O)N([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])C2(OC([H])([H])C([H])([H])O2)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
CNC1=NC(NC2=C(C)N(N=C2)C(C)C)=NC=C1C(F)(F)F
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2N(C(=N3)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(C1=C2C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(=NC2=NC(=C([H])N12)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NN(C2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(N([H])C2=NS(=O)(=O)N=C2N([H])[C@@]([H])(C2=C([H])C([H])=C3N(C([H])([H])[H])C([H])([H])C([H])([H])OC3=C2[H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])N(C([H])([H])[C@]([H])(O[H])C([H])([H])O[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C([H])=C([H])C(=O)N([H])C1=NC2=C(N=C([H])N=C2N([H])C2=C([H])C(Br)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=NC([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C(=C([H])C([H])=N2)C([H])([H])[H])C([H])([H])C1([H])[H]
CNC1=NC(C)=C(S1)C1=NC(NC2=CC(=CC=C2)S(N)(=O)=O)=NC=C1C#N
[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C([H])=C2N=C([H])C([H])=C(O[C@]3([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C2=C1[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(=O)C1=NC([H])=C([H])N1C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(N([H])C(=S)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C3=C(C([H])=C(O[H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C([H])([H])C(=O)O[H])=C([H])C([H])=C1C1=C2C([H])=C([H])C(=O)C([H])=C2OC2=C1C([H])=C([H])C(O[H])=C2[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C(=NN1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(N=C(C(=N1)C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2Br)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(C2=C3N=C(N=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])N(C([H])=N1)C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])N(C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(F)(F)F
[H]N=C(N([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])N(C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1Cl)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(N(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C2C(=O)C3=C(N([H])N=C3C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])O1
[H]N(C1=NC2=C(C([H])=C([H])N2C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])=N1)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C3OC([H])([H])C([H])=C([H])C3=C12
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(N1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@]1([H])N([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C1=NC(N([H])C2=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C2[H])=C(C(=O)N([H])[H])C2=NC([H])=C([H])N12
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N2C([H])([H])C3=C(C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]ON([H])C(=O)C1=C([H])N(C(=O)C(F)=C1N([H])C1=C([H])C([H])=C(Br)C([H])=C1F)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)N([H])C(=O)C(=C([H])C2=C([H])C([H])=C(O2)SC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=O
[H]N([H])C1=NC(N([H])[H])=C2C(=N1)C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])N1C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(C([H])=N1)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])F)C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(OC([H])([H])C([H])([H])N2S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C1=NS(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C(=C([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(C#CC2=C([H])N=C3C([H])=C([H])C([H])=C([H])N23)=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C([H])C(Cl)=C1Cl)C1=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@@]1([H])C(=O)N(C([H])([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]([H])(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
CN(C)C(=O)CC1=CC2=C(C=C1)C=CC1=C(C=C(C=N1)C1=CN(C)N=C1)C2=O
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])[C@]([H])(C([H])([H])[H])[C@@]2([H])OC([H])([H])C(=O)[C@@]12[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]O[C@]1([H])[C@@]([H])(C([H])([H])N([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])C2([H])C3([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C3([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=NN=NN1C1=C([H])C([H])=C([H])C(Cl)=C1Cl)C([H])([H])[H]
[H]N(C1=C2N([H])C([H])([H])C3=C(OC2=NC([H])=N1)C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C([H])=C(C2=C1C([H])=C([H])C(=C2[H])N(C([H])([H])C(F)(F)F)C([H])([H])C(F)(F)F)C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C(=O)N([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(F)=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
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[H]N(C(=O)C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])N(C1=O)[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C1=NC([H])([H])C([H])([H])C([H])([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC2=C(S1)C([H])=C(C([H])=C2[H])C([H])([H])[H]
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[H]ON([H])C(=O)[C@@]([H])(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])N(C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N/C(=O)N([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])\N([H])[H]
[H]OC(=O)[C@@]1([H])OC([H])([H])C2=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])[C@]3([H])SC(SC3([H])[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC1=C2C([H])=C(N(C2=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=N[H])N([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]1([H])N(C(=O)C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C(C([H])=C(S1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C(C([H])=C2N=C(N=NC2=C1[H])N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2N=C([H])C(OC(F)(F)F)=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=NC(=C(S1)C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=N1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(C3=C([H])C([H])=C(O[H])C([H])=C3O[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])O2
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(C#N)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C1C([H])=C([H])C(Cl)=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1N1C([H])([H])C([H])([H])C2(C(=O)N(C([H])([H])C3=C4C([H])=C([H])C([H])=C([H])C4=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C([H])=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C(=C([H])C([H])=C3[H])[C@]([H])(O[H])C([H])([H])[H])C2=C1[H]
[H]C1=C(C(=O)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C(Cl)=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)N([H])[C@@]2([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N1N=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(N1[H])C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(=O)N([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])[H])=NN=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C2OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3N(C2=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])[C@@]([H])(OC([H])([H])C1=C(C([H])=C(C#N)C([H])=N1)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C2N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C13)C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])C([H])([H])[H])C([H])([H])N([H])[C@]([H])(C([H])([H])N([H])[C@]([H])(C([H])([H])N([H])[C@]([H])(C([H])([H])N([H])[C@]([H])(C([H])([H])N([H])[C@]([H])(C([H])([H])O[H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])C2=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1SC2([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N=C(S2)N([H])C2=C([H])C([H])=C([H])N=C2[H])C([H])=C1[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(OC(=O)C([H])=C2C([H])([H])C([H])([H])[H])N=C1C(F)(F)F
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C(F)=C(F)C([H])=C1[H])[C@@]1([H])C([H])([H])N(C(=O)C([H])=C([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N1C(=C(C#N)C(=C1C([H])([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(=O)N([H])C(C1=NN=NN1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=NN(C(=O)C(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=NC2=C(S1)C([H])=C([H])C(=C2[H])C(F)(F)F
[H]OC([H])([H])C([H])([H])ON([H])C(=O)C1=C(N([H])C2=C(F)C([H])=C(Br)C([H])=C2[H])N(C2=C1C([H])([H])C([H])([H])C([H])([H])C2=O)C([H])([H])[H]
[H]C1=C([H])C2=C(C(=NC2([H])[H])C2=C([H])C(=NC([H])=C2[H])N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])OC3([H])[H])C(OC([H])([H])[H])=N1
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C(Br)N=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]1(C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])OC4=C([H])C([H])=C([H])C([H])=C34)[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=O
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C3=NC([H])=NC(N([H])C4=NN([H])C(=C4[H])C([H])([H])C(=O)N([H])C4=C(F)C(F)=C([H])C([H])=C4[H])=C3C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1C([H])([H])[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]OC1=C([H])C([H])=C(C2=NN(C(=O)C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C2([H])[H])C(O[H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(=O)C(N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC([H])([H])C([H])([H])N(C1=NC2=C(N=C([H])N2[C@]2([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]2([H])O[H])C(SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)=N1)C([H])([H])C([H])([H])O[H]
[H]N1C(=O)N(C2=C1C([H])=C(C([H])=C2[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])[C@]12[H])C([H])([H])[H]
[H]O[C@@]1(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])OC2=C([H])C([H])=C3C(C([H])=C4C(=O)OC([H])([H])C4=C3C3=C([H])OC([H])=C3[H])=C2[H])C([H])([H])[C@]2([H])OC([H])([H])[C@@]([H])(O2)C1([H])[H]
[H]OC1=C(O[H])N=C2C(=N1)C([H])=C(Cl)C(OC([H])([H])[H])=C2[N+]([O-])=O
[H]N(C(=O)[C@]([H])(N1C(=O)C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C([H])C([H])=C1F)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C([H])C(=C([H])N=C1N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NN(C([H])=C1[H])[C@@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(=O)C1=C([H])C2=C(N1[H])C([H])=C(C([H])=C2[H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C(=C1[H])C([H])([H])[H])N([H])[H]
CC(C)(C)NC(=O)NCCCN1CCN(CC(=O)NC23CC4CC(CC(C4)C2)C3)CC1
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(N([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C(=C1[H])C1=NN=NN1C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC3=C(S2)N=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]N1C2=NC3=C(N2C([H])=C1C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N3C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C2=C(OC([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(=C23)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C#C[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])N([H])[H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([O-])=O
[H]N(C(=O)N(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C2O[C@@]3([H])C([H])([H])N(C([H])([H])C([H])([H])C4=C([H])C([H])=C(C([H])=C4[H])[N+]([O-])=O)C([H])([H])C([H])([H])[C@]3(C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C1=NC(=C([H])N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(C2=NC(=C3N2C([H])=C([H])N=C3N([H])[H])C2=C([H])C(OC([H])([H])[H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1([H])[H]
[H]O[C@@]1([H])C2=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C2O[C@]2(C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C3=C([H])C4=NON=C4C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C1=NC(=NC([H])=C1Cl)S(=O)(=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=NC(=NC([H])=C2C([H])=C1C1=C(Cl)C([H])=C([H])C([H])=C1Cl)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC(=O)C([H])([H])C([H])([H])N1C(=O)C2=C(C1=O)C(=C([H])C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]12C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3C([H])=C([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C(N=C23)C#CC([H])([H])[C@@]([H])(O[H])C([H])([H])[H])N([H])OC([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])N1C(=C([H])C(C(=O)C([H])([H])OC2=C([H])C3=C(C([H])=C([H])C(=O)O3)C([H])=C2[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C([H])=S1(=O)C([H])([H])C([H])([H])C([H])(N([H])C2=C([H])C([H])=C([H])C(SC3=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C(=C3C(F)(F)F)C(F)(F)F)=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NOC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C(F)=C(F)C(F)=C2[H])C([H])([H])C1([H])[H]
O=C(CCCC1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1)CC1=CC=CC=C1
[H]N(C(=O)[C@@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C(=O)OC([H])([H])[H]
[H][C@]12CC[C@H](N1C(=O)[C@H](CN(CC2)C(=O)N1CCN(CC1)C(=O)N1CC[C@@]2([H])CC[C@H](N2C(=O)[C@H](C1)NC(=O)[C@H](C)NC)C(=O)NC(C1=CC=CC=C1)C1=CC=CC=C1)NC(=O)[C@H](C)NC)C(=O)NC(C1=CC=CC=C1)C1=CC=CC=C1
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C2([H])[H]
[H]N(\C(N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C(\C#N)C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1N([H])C([H])=C2Br
[H]N(C(=O)C1=C([H])C([H])=C2N(C([H])=C(C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C(=O)N([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=C(\[H])C(F)(F)F)\C([H])([H])[H]
[H]C1=C([H])C(=O)C([H])=C([H])N1C([H])([H])C1=NN=C2N=C([H])C(=NN12)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(\C([H])=C(\C2=C([H])C3=C(SC([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])C(=O)N([H])C1=C([H])C2=C(N=C([H])N(C2=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])C([H])([H])C([H])([H])N2[H])=C([H])C(O[H])=C1[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1O[H]
[H]N(C(=O)C1=C([H])C(\C([H])=C(/[H])N2C([H])=NC3=C(N=C([H])N=C23)N([H])C2([H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C(N2C([H])([H])C([H])([H])N(C(=O)[C@]3([H])C([H])([H])OC([H])([H])[C@]3([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C(F)=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=NC(=C([H])C([H])=C1[H])C1=C(C2=C([H])C(Cl)=C([H])C([H])=C2OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])N(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]OC1=C([H])C([H])=C([H])C(C2=NC3=C(N2[H])N(C(=O)N(C3=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C1O[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])N1C2=NC3=C(N2C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]1([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=NC([H])=C2C([H])([H])C(=O)C2=C([H])C([H])=C(F)C(=N2)C2=C(F)C(F)=C([H])C([H])=C2F)C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C2N=C(SC2=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C(OC([H])([H])C([H])([H])C(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])N=C(OC([H])(F)F)C([H])=N1
[H]N(C(=O)C1=C([H])C(=C(S1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=S)N(N=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N3C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C4C([H])([H])C([H])([H])[C@@]3([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(=C2[H])C([H])([H])C([H])([H])[H])[C@]1([H])C(=O)N(C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[H]
[H]O[C@]([H])(N1N=C(N=C1N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C(=C(N([H])C2=C([H])N=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])=C1[H])C([H])([H])[H])C([H])=O
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
NCCCC[C@H](N)C(=O)N1CCN(CC1)C1=NC(=NC(=N1)N1CCOCC1)N1C(=NC2=CC=CC=C12)C(F)F
[H]N(C(=O)C1=C([H])C(=NN([H])C1=O)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C(=O)N([H])S1(=O)=O
[H]C1=C([H])C(=NC(OC2=C([H])C3=C(C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])C3([H])[H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]([H])(N1C(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(N([H])C(=O)C([H])([H])SC1=NN=C(N1N([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@](C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(N([H])[H])=C2[H])C([H])([H])C1([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C(F)(F)C1([H])[H]
[H]OC(=O)C(N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])SC([H])([H])C([H])([H])N1C(=O)C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C1/C(=O)N([H])N=C1C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])OC([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])N1N=NC2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]C1=NC(=O)N(C([H])=C1C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=NC2=C(C([H])=C3C(N([H])C4(C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C2[H])C(=C1[H])C(F)(F)F
[H]S\C(=N/C1=C([H])C([H])=C(C([H])=N1)[N+]([O-])=O)N([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=C(C([H])=C(C([H])=N1)S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C1=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])SSC(C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])[C@]([H])(O[H])C([H])([H])[H]
CNC(=O)C1=CC=CC(=C1)C1=CC=C2C(N=C(N=C2N2CCOC[C@@H]2C)N2CCOC[C@@H]2C)=N1
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC3=C(S2)C([H])=C(Cl)C([H])=C3[H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]1(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C(=C1C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(=O)[C@]1([H])N(C([H])([H])C2=C(C([H])=C([H])C(N([H])[H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1N=C([H])C(=C1[H])C1=NN2C(=NN=C2C([H])([H])C2=C3C([H])=C([H])N([H])C(=O)C3=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])S[C@@]([H])(N(C1=O)C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C([H])C(=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC([H])=C(C([H])=N1)C1=C([H])C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H]
[H]C([H])=C([H])C1=NC(Cl)=C(OC([H])([H])C([H])([H])OC2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]N1C(=O)C([H])=C([H])N(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=NC(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H]
O=C(CCCCC1CCSS1)OC1CCN(CC2CCCCC2)CC1
[H]OC1=NC(=NC2=NN(N=C12)C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])P(=O)(O[H])O[H])N([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C(C([H])=C([H])C(Cl)=C1[H])N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C(=O)[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=NN(C(=O)C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NN(C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C([H])C([H])=C([H])C([H])=C4N=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C(S1)C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N([H])C([H])([H])C([H])([H])SC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C1=C([H])C([H])=C2N=C([H])N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN=NN1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])N([H])C([H])([H])C([H])([H])S[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
OC(=O)C1CN(C1)C1=CC2=C(OC(=N2)C2=CC=C(C3=CC=CC=C3)C(=C2)C(F)(F)F)C=C1
[H]OC(=O)C([H])([H])C([H])([H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])N1[H])C1=NN([H])C([H])=C1C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
COC1=CC=CC(SC2=NN3C(C=C2)=NN=C3C2=CN=CS2)=C1
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C([H])=C2N=C(N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C(C2=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=O)C([H])([H])[H])C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C3([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C2=C(N([H])C([H])=NC1([H])[H])N(C([H])=N2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H]
[H]N1C([H])=C(\C([H])=C(/[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])N(C([H])=N1)[C@@]1([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2O[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(F)C([H])=C1[H])[C@@]([H])(C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
CN1C=C(C2=NC3=C(O2)C=C(CC(=O)N2C[C@@H](F)C[C@H]2CO[C@H]2CC[C@@H](CC2)C(O)=O)C=C3)C2=C1C=CC(Cl)=C2
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C2C([H])=C([H])C(OC3=C([H])C([H])=NC4=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C34)=C([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]O\N=C1/C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
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[H]N(C(=O)C1=C([H])C([H])=C([H])C(Br)=C1[H])[C@@]1([H])[C@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C1=C2C(=NC3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N1C2=C(C([H])=C(S2)C(C(=O)N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC([H])([H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N(C(=O)C3=C([H])C([H])=C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2=C1[H]
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[H]C1=C(ON=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])N=C([H])C(=C1[H])C1=C([H])N2C(=NC([H])=C2C2=C([H])N=C([H])C([H])=C2[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C(=C2C3=C(C([H])=C(Cl)C([H])=C3[H])C([H])([H])C([H])([H])C3=C2[N+]([O-])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
COC1=CC=C2N(C(=O)C3=CC(=CC=C3)C(F)(F)F)C3=C(CC(CC3)C(O)=O)C2=C1
[H]N(C(=O)C1=C(N=C(S1)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N1C(=C([H])C(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C(Cl)C([H])=C(Cl)C(=C1[H])C1=C2N=C(N=C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=NN1C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C(=O)C2=C([H])C(C3=C([H])N=C([H])O3)=C(OC([H])([H])[H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=NC(OC2([H])C([H])([H])N(C3=NC4=C(C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C2([H])[H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C2C([H])=C([H])C([H])=C(C2=C1[H])S(=O)(=O)N(C([H])([H])[H])[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OS(=O)(=O)C2=C3C([H])=C([H])N=C([H])C3=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@@](C(=O)O[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N([H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)C1=NC([H])=C([H])S1)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C(=O)C([H])([H])OC1=NC(=C2C(=C1C#N)C([H])([H])C(OC2([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2O1
[H]N1C(=NC2=C([H])C(OC(F)(F)F)=C([H])C([H])=C12)[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(OC(=O)N(C3=C([H])C([H])=C([H])C([H])=N3)C2([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)[C@@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])C1=NN=NN1C1=C(Cl)C(Cl)=C(F)C([H])=C1[H]
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[H]N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C(SC([H])([H])C2=NC([H])=C(O2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S1
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[H]OC1=C([H])C2=C(OC(=O)C3=C2C2=C(C([H])=C([H])C([H])=C2N3[H])C(F)(F)F)C([H])=C1[H]
[H]ON([H])C(=O)C1=C([H])N=C(N=C1[H])N([H])C1=NN=C(S1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(\N=N\C1=C([H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C([H])C([H])=C3[H])C2=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])Cl
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[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(SC(=N1)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)OC([H])([H])[H])C2([H])[H]
[H]OC1=C2C([H])=NC([H])=C([H])C2=NC(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1C#N
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[H]C1=C([H])C(=C([H])C([H])=C1N1N=C(C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(F)(F)F)C([H])([H])C(=O)C([H])([H])[H]
[H]C1=C([H])C(N(C([H])([H])[H])C([H])([H])[H])=C2C(SC3=C2N=C([H])N(C3=O)C2=C([H])C([H])=C(C([H])=C2[H])C2([H])C([H])([H])C2([H])[H])=N1
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
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[H]N(\N=C(/C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C(=O)C1=C([H])C([H])=NC([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C(SC([H])([H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=NC(=C1C1=C([H])C([H])=NC(N([H])C(=O)C([H])([H])[H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])SC1=NC(=O)N(C([H])=C1[H])[C@]1([H])O[C@]([H])(C([H])([H])O[P@@](=O)(O[H])OP(=O)(O[H])O[H])[C@@]([H])(O[H])[C@@]1([H])O[H]
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[H]N([C@]1([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1Cl)C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)S1
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])[C@@]([H])(C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C(=O)N(C2=C(\C([H])=C(/[H])C(=O)N([H])S(=O)(=O)C3=C([H])C(F)=C(F)C([H])=C3[H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N1C([H])([H])[C@]2([H])C([H])([H])C([H])([H])N(C3=C([H])N=C(Cl)C(=C3[H])C([H])([H])[H])C([H])([H])[C@]12[H]
[H]OC(C1=C([H])C2=C(C([H])=C1[H])C1=C(N=C(N1[H])C1=C(C#N)C([H])=C([H])C([H])=C1C#N)C1=C2C([H])=C(Cl)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C([H])C4=C(N=C(O4)C4([H])C([H])([H])C4([H])[H])C([H])=C3C([H])([H])C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2S1(=O)=O
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@]1([H])C([H])([H])O[C@@]([H])(O[C@]1([H])C1=C(O[H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H])\C1=C([H])N=C([H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C([H])C([H])=C3[H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C2=C1C(=O)C(OC([H])([H])C([H])([H])[H])=C(O2)C1=C([H])C([H])=C([H])C([H])=C1[H]
CC(=O)OC[C@@H](NC(=O)c1cc(c[nH]1)-c1nc(Nc2ccccc2)ncc1C)c1ccccc1
[H]N(C1=NN(C2=C1C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C#N
[H]C1=C([H])C2=C(O1)C([H])=C([H])C(=C2[H])C1=C([H])N=C(N=C1[H])N1C([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])[C@]1([H])C2([H])[H]
[H]C1=NC(OC([H])([H])[H])=C([H])C([H])=C1N(C(=O)N1C([H])([H])C([H])(OC2=C(C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])N([H])C(=O)[C@@]2([H])[C@]1([H])C1=C(C([H])=C(OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])[C@]2(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C([H])N=C(S1)C1=C([H])C([H])([H])[C@]([H])(N(C(=O)N([H])C2=C([H])C(Cl)=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C2=C(C([H])=C([H])C(=C2[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])C2([H])C([H])([H])C2([H])[H])=C(OC([H])(F)F)C([H])=C1[H]
[H]OC1=C2N=C([H])C([H])=C(C2=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C#C[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])C([H])([H])[C@](C3=C([H])C([H])=C([H])C([H])=C3[H])(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]12[H]
[H]O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[N+]([O-])=O
[H]C1=C([H])N2C(=C1[H])C(OC(=O)C([H])([H])[H])=C(OC1=C([H])C([H])=C([H])C([H])=C21)C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])OP([O-])(=O)O[H])[N+]1([H])[H]
[H]N(C1=NC(=NC([H])=C1C(=O)OC([H])([H])C([H])([H])[H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C(=C([H])C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C1=N[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(C(=O)OC([H])([H])[H])[C@]([H])(N1C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(S1)C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])O[C@@]21[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H]
[H]S\C(=N\C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]C1=C([H])C(=C(C(=O)N2C([H])([H])[C@@]3([H])C([H])([H])N(C([H])([H])C([H])([H])C4(C5=C([H])C([H])=C([H])C([H])=C5[H])C([H])([H])N(C(=O)C5([H])C([H])([H])C([H])([H])C(F)(F)C([H])([H])C5([H])[H])C4([H])[H])C([H])([H])[C@@]3([H])C2([H])[H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C(OC([H])([H])[H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C2C(=C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C#C[H])C2([H])[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC([H])=C(SC([H])([H])C3=NC([H])=C(O3)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S2)C1([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C1=C([H])C(=C2N=C(N([H])C2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NN=NN1C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])F)C1=NN2C(N=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2OC1=O
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])[C@@]([H])(S[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N(C1=C([H])C([H])=C([H])C([H])=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])N(C(=O)C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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COC1=CC(=CC=C1Cl)N1CCN(CC1)C(=O)CN1N=C(C(O)=O)C(Cl)=C1C
[H]OC1=C(C([H])=C([H])C([H])=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C2=C([H])N=C([H])C([H])=C2N1[H]
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[H]OC1=C(C(=O)C(\[H])=C(/[H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC(O[H])(C([H])([H])N1C(=O)S\C(=C(\[H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1=O)C(F)(F)F
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[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(F)C(F)=C(F)C(F)=C2F)C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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[H]O[C@@]([H])(C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC(=O)C1=C([H])C([H])=C(C(N([H])C(=O)C2=NC3=C(S2)C([H])([H])N(C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]SC([H])([H])[C@]([H])(N([H])[H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C(=C([H])N=C12)C1=C([H])C([H])=C([H])C(=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C([H])([H])OC(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])S2)C([H])=C1[H])C1=NC2=C(S1)C([H])=C(F)C(F)=C2F
[H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C2=C1[C@]1([H])N(C2=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])=C([H])C([H])=C(C1=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])[H])C([H])([H])OC1=C([H])N2N=C([H])N=C(N([H])C3=C([H])C4=C(N=C3[H])N([H])C(=C4[H])C([H])([H])[H])C2=C1C([H])([H])[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2C(C#N)=C1[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C2=C([H])SC([H])=C2[H])C1([H])[H]
[H]C(=O)N(C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)N2C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[C@@]2([H])C1=O
CN1C(C)=CC2=C1C(=NN=C2NCCCN1CCN(CC1)C(=O)C1=NC=CN=C1)C1=CC=CC(=C1)N(O)=O
[H]N([H])C1=C2C([H])=C([H])C(=C([H])C2=C([H])C([H])=N1)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(OC([H])([H])[H])C(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])ON([H])C(=O)C1=C(N([H])C2=C([H])C([H])=C(I)C([H])=C2F)C(F)=C(F)C(=C1[H])C([H])([H])N([H])OC([H])([H])C([H])([H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NN=C(S1)N=C(N([H])[H])N([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N(C(=O)[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(Cl)=C([H])N(C1=O)[C@@]([H])(C([H])([H])OC([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C1=C(C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C#CC1=C([H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(N([H])S(=O)(=O)C2=C(N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C(Cl)C([H])=C2[H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]O[C@@]([H])(C1=NC(=C([H])N1[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
CCNC1=NC(C(N)=O)=C2CN(CCC2=N1)C(=O)CCC1=CC=C(C)C=C1
[H]N=C(N([H])[H])C1=C([H])C(N([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)O[C@@]1([H])[C@@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])[C@@]2([H])N([H])[C@]([H])(C1([H])[H])C([H])([H])C(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(F)C([H])=C([H])C(F)=C1Cl)=C2C(=O)N(C([H])([H])C1=C(C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C(=O)C1=C([H])OC2=C([H])C([H])=C(OC([H])([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])C([H])=C2C1=O
[H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1C2=C(C([H])=C(F)C([H])=C2[H])C2=C1C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C2([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C(=O)O[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(N=C2[H])N2C([H])([H])[C@@]3([H])N(C(=O)OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]([H])(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]C1=NC([H])=C(N=C1[H])C1=C([H])C(F)=C(C([H])=C1[H])C1=NN=C(N1C([H])([H])[H])C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]