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[H]N(C1=NC([H])=C2C([H])=C([H])N(C2=N1)C1=C([H])C([H])=C([H])C([H])=N1)C1=C(SC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)C([H])([H])C([H])([H])N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=NC([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O[C@@]2([H])C([H])([H])N(C3=NN=C(N3C3=C([H])C([H])=C(OC([H])([H])[H])N=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[C@@]([H])(O[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1F)C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N([H])C(C2=C([H])C([H])=C(C([H])=C2[H])N2C(=NC(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]1([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2N([H])C2=C(C([H])=NN2C([H])([H])[H])C1([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=NC2=C([H])C(Cl)=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C1=NC2=C(N=NN2C2=C1SC([H])=C2[H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C1=NC(=NN1C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
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[H]OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=C(OC3([H])C([H])([H])N(C4=C([H])C([H])=C5C([H])=C([H])C([H])=C([H])C5=N4)C3([H])[H])N=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])([H])C1([H])[H]
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[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(O[H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=NN(\C(S1)=N\C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C(=C([H])N=C1[H])C1=C([H])N=C(S1)N([H])C1=NC([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=NC2=C([H])C(=NN12)C1=C([H])N=C([H])N1[H]
[H]OC([H])([H])[C@@]1([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2[H])N2N=C([H])C3=C(N([H])C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C4([H])C([H])([H])C4([H])[H])C([H])([H])[H])C([H])=C(C([H])=C23)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=NC([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])=C([H])C([H])=C12)C(=O)OC([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])C11C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2F)C([H])([H])C2=C([H])N([H])C(=O)C3=C([H])C(Cl)=C(Cl)N23)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])[C@@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])[C@]([H])(OC([H])([H])C1=C(C([H])=C(C#N)C(=O)N1C([H])([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)N([H])[C@@]([H])(C([H])([H])[H])[C@]([H])(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
NC1=C2CCCCC2=NC2CCCCC12
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])S(=O)(=O)C(F)(F)F)[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3(C(=C([H])C(=O)[C@]4([H])[C@@]5(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]5([H])C([H])([H])C([H])([H])[C@@]34C([H])([H])[H])[C@]2([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C(Cl)C(C#N)=C1[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C(C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C(F)C(Cl)=C([H])C([H])=C1[H]
[H]C1=C(Cl)C([H])=C(OC([H])([H])[H])C(=C1[H])C1=NC(=NN1C([H])([H])[H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1N=NN=C1C1=NN([H])C2=C1C([H])([H])[C@@]([H])(C1=C([H])C(F)=C([H])C(F)=C1F)C2([H])[H]
[H]\C(=C(\[H])C1=C(OS(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])C2=C([H])C(OC(F)(F)F)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C(=N\OC([H])([H])[H])\C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]\C(=C(\C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@]1([H])C([H])([H])O[C@]([H])(O[C@@]1([H])C1=C([H])N=C([H])C([H])=C1[H])C(OC1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=NN=C(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CC[C@@H](C1)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](C(=C)C(N)=O)C1=CC=CC=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC([H])=C1[H])C1=C([H])C([H])=C2N=C([H])SC2=C1[H]
[H]N1C(=O)C([H])([H])[C@]([H])(OC(=O)[C@@]([H])(N([H])C(=O)C2=C([H])SC(=N2)C2=C([H])SC(=N2)C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(\[H])=C(/[H])C([H])([H])C([H])([H])SC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=C([H])C3=C(C([H])=C2[H])C([H])=C(O[H])C([H])=C3[H])C([H])([H])C([H])([H])[C@@]([H])(C2=C(F)N=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]3([H])C([H])([H])C4=C([H])N(N=C4[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H])C([H])([H])C([H])([H])C#N
[H]C1=C([H])C([H])=C(O1)C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(C([H])=C1S(=O)(=O)N1C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C3=NC([H])([H])C([H])([H])N3C([H])([H])[H])[C@@]([H])(C([H])([H])C(=O)OC([H])([H])[H])C1([H])[H])C([H])=C(Cl)C([H])=C2[H]
[H]OC1=C2C(=NC(=N1)N([H])[H])N([H])C(=C2SC1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H]
[H]O[C@]1([H])[C@]2([H])C([H])([H])[C@]2([H])[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])C([H])([H])C([H])([H])[H])[C@]1([H])O[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C(Cl)=C(C([H])=C1[H])C([H])([H])N1C(=NC(=C1C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@@](=O)(O[H])O[P@@](=O)(O[H])O[P@@](=O)(O[H])O[P@@](=O)(O[H])OC([H])([H])[C@@]2([H])O[C@]([H])(O[H])C([H])([H])[C@@]([H])(O[H])[C@]2([H])O[H])[C@@]1([H])O[H])N1C([H])=C([H])C(=O)N([H])C1=O
O=C1SC2=CC=CC3=CC=CC1=C23
[H]C1=C([H])C(N(C([H])([H])[H])C([H])([H])[H])=C2C(SC3=C2C([H])=C([H])N(C3=O)C2=C([H])C([H])=C(C#N)C([H])=C2[H])=N1
[H]N1N=C2C3=C([H])C([H])=C(C([H])=C3C([H])([H])C2=C1[H])C1=C([H])N(N=C1C1=C([H])C([H])=NC([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])F
[H]N(C(=O)C([H])([H])N([H])C(=O)[C@@]1([H])N([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C2C([H])=C([H])C([H])=C([H])C2=NC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])C2=C([H])C(=C([H])C([H])=C2OC1(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OP(=O)(O[H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C#CC1=C([H])C([H])=C(F)C([H])=C1F
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=C([H])[H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N1N=C(C(=C1C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N=C1SC([H])=C(N1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C(=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]C1=C(Br)SC(C(=O)C([H])([H])Br)=C1Br
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])[C@@]1([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[C@]1([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]OC1=C(C(=C2N=C(SC2=C1C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])N([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N([H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=NOC(=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C(N([H])C(=O)C([H])=C2[H])C1=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]2([H])C(=O)OC([H])([H])[C@]12[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C(N2C([H])=C([H])C([H])=C([H])C2=N1)C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N(C1=O)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(SC3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C3=C(N=C([H])C([H])=C3N2C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C(OC([H])([H])[C@]([H])(N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])Cl)C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@@]1([H])SC2=C([H])C(O[H])=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]C1=C(C([H])=C([H])C(=N1)C([H])([H])[H])C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C([H])C([H])=C4OC(=NC4=C3C([H])([H])C2([H])[H])C(F)(F)F)N1C([H])([H])[H]
[H]N([H])[C@]1([H])C(=O)N([H])C(=O)[C@](OC2=C([H])C([H])=C(OC3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])=C2[H])(C1=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC2=C(C([H])=N1)C([H])=C(C(=N2)N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C1=NC(OC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C2N=C([H])N([H])C2=N1)C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])N(C4=C([H])C(=C([H])C([H])=C34)C(F)(F)F)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C2=C(N([H])C([H])=C2C([H])([H])C([H])([H])N([H])[H])C([H])=C1[H]
CN(C)CCCOC1=NC2=C(CCCC2=O)S1
[H]OC1=C([H])C([H])=C([H])C2=C([H])C(N([H])C(=O)C3=C([H])C4=C(N3[H])C([H])=C([H])C(Cl)=C4[H])=C([H])C([H])=C12
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C(C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])\C(=N\C2=C3C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C3=NC([H])=N2)C(=O)C(Cl)=C1OC([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])\N=C(/S[H])N([H])C2=C(F)C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C1=C([H])C([H])=C2C(=O)C3=C(N([H])C2=C1[H])C([H])=C([H])C([H])=C3[H])C(C1=NC([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=O)C(=O)C(C2=C([H])N([H])C3=C2C(Cl)=C([H])C(Cl)=C3C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C1O[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2OC([H])([H])C([H])([H])[H])C([H])([H])C2=NC([H])=C(S2)C2=C([H])OC([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C1=NOC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])[C@@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N([H])C1=NC([H])=C(\C([H])=C(/[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C(=C([H])S2)C1=C([H])C(OC([H])([H])[H])=C(N([H])C(=O)C2=C([H])C3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C2C([H])=C(C([H])=C([H])C2=N1)N(C([H])([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C(C(=C2O[C@]([H])(SC2=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C2=C(C([H])=N1)C(=NC([H])=N2)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C(OC([H])([H])[H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])(N3C(=O)OC([H])([H])C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C(=C(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1O[H])C1=C([H])C([H])=C(O1)C(\[H])=C1/SC(=S)N(C1=O)C([H])([H])C(=O)O[H]
[H]N(C([H])([H])C([H])([H])OC1=C([H])C(F)=C([H])C2=C1OC([H])([H])C([H])([H])C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C(C([H])([H])C([H])([H])[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2C#N)C([H])=C1[H]
[H]N1N=C(C(=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C(\N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C3N([H])N=C(C3=C2[H])S(=O)(=O)C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(N([H])C(=O)[C@]1([H])SC([H])([H])C([H])([H])N1C(=O)C([H])([H])[H])C(=O)C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC2=C(N1[H])C([H])=C(C([H])=C2[H])C(F)(F)F)C1=C([H])C([H])=C(OC2=NC([H])=C([H])C([H])=C2C2=NC(=NC([H])=C2[H])N([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(N([H])C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1[H]
[H]C1=C([H])C2=C(O1)C([H])=C([H])N=C2N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C(=O)C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])[C@]1([H])N(C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N(C1=O)[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N([H])C1=C([H])C(=C(N([H])C(=O)N([H])C2=C(C3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C3[H])C3=C(N=C([H])C([H])=C3[H])N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C(=O)C4=C([H])C([H])=C(C([H])=C4C3([H])[H])C3=C([H])C([H])=C([H])C([H])=C3S(=O)(=O)N([H])[H])C([H])=C12
[H]OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]N(C1=NC(OC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C2N=C([H])N([H])C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C2C([H])=NN1[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N([H])[C@]([H])(C1=NN=C(O1)SC([H])([H])C(=O)N([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C([H])C(=N1)C1=NOC(=N1)C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C2N=C(SC([H])([H])C(\[H])=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N([H])C(=O)C1=NC(=NO1)N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C([H])C(C#N)=C(C([H])=C1O[C@@]1([H])C(=O)N(C([H])([H])C2=NN=C(O2)C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C(F)C([H])=C([H])C(=C1F)S(=O)(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)P(=O)(O[H])O[H]
[H]N1C(=O)N(C2=C(N=C(SC3=C([H])C([H])=C(F)C([H])=C3Cl)C([H])=C2[H])C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N(C1=NC(OC([H])([H])[H])=C(C([H])=N1)C(=O)N([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C1([H])[H])C([H])([H])[H]
[H]OC1=NSC(N([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])=C1C#N
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]1([H])C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]\C(=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C1=NC(=C([H])O1)C1=C([H])N=C([H])C([H])=C1[H]
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[H]C([H])=C([H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])N=C(N=C12)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC1=C(C(C2=C([H])C([H])=C(F)C([H])=C2[H])=C(OC([H])([H])[C@]([H])(O[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O)C(=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC1=NC2=C([H])C(Cl)=C(Cl)C(Cl)=C2C(O[H])=C1N=O
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[H]N([H])C1=C([H])C([H])=C(C(=N1)C([H])([H])[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C([H])C([H])=C1C1([H])C([H])([H])C1([H])[H]