[H]OC1=C(C([H])=C([H])C([H])=C1N([H])C1=C(N([H])N(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])[H])C(=O)C1=O)C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(OC(=O)N([H])C1=C(Cl)C([H])=C([H])C(Cl)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])F
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
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[H]N1C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])N2C3=C(C([H])=C([H])C([H])=C3[H])C3=C([H])C(=C([H])C(OC4=C([H])C([H])=C(Cl)C([H])=C4[H])=C23)C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C2([H])[H])[C@]([H])(F)C1([H])[H]
[H]OC1=C(C([H])=C([H])C(\C([H])=C(/[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(\C([H])=C(/[H])C(=O)OC([H])([H])[H])=C1[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)N2C([H])=NN=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2N(C(=O)OC2=C1[H])C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=NC(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=C(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(O[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([O-])=O)C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C1=NC(N([H])C(=O)C2=C([H])C([H])=C([H])S2)=C(C#N)C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N([H])[H]
[H]C1=C(C2=C([H])N=C([H])C([H])=C2[H])[C@@]2(C([H])([H])[H])C([H])([H])C(=O)[C@]3([H])[C@]([H])(C([H])([H])C([H])([H])C4=C([H])C(=O)C([H])([H])C([H])([H])[C@]34C([H])([H])[H])[C@@]2([H])C1([H])[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])SC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(N(N=C1C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[C@]1([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N(C(=O)C1=C(N2N=C([H])C([H])=C([H])C2=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2[H])C([H])([H])C2=NN=C(S2)C2=C([H])N=C(S2)C2=C([H])C([H])=NC([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
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[H]C1=NN(C(=O)C(C2=C([H])C([H])=C(F)C([H])=C2[H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(S1)C(=NC([H])=N2)N([H])C1=C([H])C(Cl)=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=N1)C([H])([H])C1=C([H])C2=C(N([H])N=C2[H])C(=C1[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(N=N1)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C2=C1C([H])([H])N([H])C2=O
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[C@@]1([H])O[C@@](OC([H])([H])C1([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(OC3=C(C([H])=C([H])C(F)=C3[H])C([H])([H])[H])N(C3=C(N=C([H])C([H])=C23)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C1=C(N(C2=C([H])C([H])=C(OC([H])([H])C([H])=C([H])[H])C([H])=C2C1=O)C([H])([H])C1=C(C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C([H])([H])[H])C(=O)O[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C([H])C1=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C2=C([H])C([H])=C(Cl)C([H])=C2C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])OC2=C(C(OC([H])([H])[H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C(C(Cl)=C([H])C([H])=C1[H])C1=C([H])C2=C([H])N=C(N=C2N(C1=O)C([H])([H])[H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(C#N)C(OC([H])([H])C([H])([H])[H])=NC(=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N1C(=O)C(C#N)=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C1C1=C(OC2([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(SC([H])=C2[H])C([H])=N1)[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C([H])=C(Cl)C(=C2[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])N([H])C(=O)C3=C([H])C([H])=C(C(=C3[H])C([O-])=O)C3=C4C([H])=C([H])C(C([H])=C4OC4=C3C([H])=C([H])C(=C4[H])N(C([H])([H])[H])C([H])([H])[H])=[N+](C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C(=O)OC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C12
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])N([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(OC2=O)C(=C(O[H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])C4=C(C5=C(N4C([H])([H])C4([H])C([H])([H])C4([H])[H])C([H])([H])C([H])([H])C([H])([H])C5([H])[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]ON([H])C(=O)[C@]([H])(N1C([H])([H])C([H])([H])N([H])C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])S1(=O)=O)C([H])([H])[H]
[H]OC([H])([H])[C@]1(OC(=O)\C(=C(\[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])OC(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(Cl)C([H])=C(C([H])=N1)C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=C2C(=NC3=C1[C@]([H])(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C(C(=O)OC([H])([H])C([H])([H])[H])=C(N3[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C1\N(C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3N=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]\C(C1=C([H])C([H])=C(O1)C([H])([H])[H])=C1\SC2=NC(=NN2C1=O)C1=C([H])C([H])=C([H])C([H])=C1Br
[H]C1=C([H])C2=C(S1)C1(OC([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C(Cl)C(=N1)C1=NN(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=NC(C2=C([H])C([H])=C([H])O2)=C2N=C([H])N(C2=N1)C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1\C(=N/C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])N(C2=C(C([H])=C(C([H])=C12)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=NN=NN1[H]
[H]N(C1=NC([H])([H])C2=C1C([H])([H])N(C(=O)N([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2(C([H])([H])[H])C([H])([H])[H])C1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C(=O)C(O[H])=C(O2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(O[H])=C1[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])[S@](=O)C([H])([H])[H]
[H]N([H])C1=NC2=C(N=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]C1=C([H])[N+](=C([H])C([H])=C1N(C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[N+]1=C([H])C([H])=C(C([H])=C1[H])N(C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])[N+]1=C([H])C([H])=C(C([H])=C1[H])N(C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H]
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