[H]C1=NN=C(N1C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C1=C(Cl)C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N([H])C(C2=C([H])C([H])=C(C([H])=C2[H])N2C(=NC3=C([H])N=C([H])C([H])=C23)C([H])([H])[H])=C(C(=O)OC([H])([H])C([H])([H])[H])[C@@]1([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])C(=O)C1(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C(C([H])=C2C([H])([H])N1[H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(N([H])S(=O)(=O)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])C2=C([H])C([H])=C([H])C(F)=C2C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C2=C1OC(=C([H])C2=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(SC(=C1[H])C1=NN=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)OC2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)C1=C([H])C2=C(OC([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])\C2=C(\[H])C([H])([H])N2C([H])=NC3=C2C([H])=C([H])C(=C3[H])C(F)(F)F)C([H])=C1[H]
[H]N([H])C1=N[C@@](C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])C(=O)C2=NC([H])=C(OC([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])C([H])([H])S1
[O-][Cl](=O)(=O)=O.CC1=CC(C)=[N+](CCC2=C(C=CC=C2)C2=CC=CC=C2)C(C)=C1
[H]N(C(=O)N([H])S(=O)(=O)N([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])\N=C(\S[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]C1=NN(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=N1)C(=O)N1C([H])([H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@](C([H])([H])[H])(C([H])([H])OC2=NC([H])=C(Cl)C([H])=C2[H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(O2)C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C2=C([H])N=C([H])N=C2[H])C([H])=C1C([H])([H])[H]
[H]\C(=C(\[H])C([H])([H])[N+]1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[N+]1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]O[P@@](=O)(OC1=C(Cl)C([H])=C([H])C([H])=C1[H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)[C@@]([H])(C(=C([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])C3=C(C(=O)C([H])([H])[C@]12C([H])([H])[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])C(=O)[C@@]([H])(C([H])([H])[H])[C@]1([H])C([H])([H])C3=O)C([H])([H])[H]
[H]ON(C(=O)N([H])[H])[C@]([H])(C1=C(OC(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC(=NC2=C([H])C([H])=C(C(SC3=C([H])C([H])=NN=C3[H])=C12)C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1S2)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(O[H])C([H])([H])[C@]([H])(O[H])C(\[H])=C(/[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]2([H])C([H])([H])N(C([H])([H])[C@]2([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])N2C(=NC3=C2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])SC2=NN=C(N2C([H])([H])[H])C2=C([H])C([H])=C([H])C4=NC(=C([H])C([H])=C24)C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]O\C(OC([H])([H])[H])=C1\C(=NC(=C(C#N)[C@@]1([H])C1=C([H])C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C2C([H])([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])C(=O)[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@]2(C([H])([H])C([H])([H])C1=O)C([H])(F)F
[H]C1=NN(C([H])=C1[H])[C@@]([H])(C(=O)N(C([H])([H])C([H])([H])F)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(OC([H])([H])C3=C2C([H])=NC(F)=C3[H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N1C([H])=C([H])C2=NC(=NC2=C1[H])C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(Cl)C([H])=C2[H]
CC1=CC=C(C(C)=C1)S(=O)(=O)N1CCC(CC1)C(=O)NC1=CC=CC2=CC=CN=C12
[H]N([H])C(=N/C1=C(C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])\N([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]OC1=NC([H])=NC(=C1[H])N1C(=O)N(C(=O)C11C([H])([H])C([H])([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=N2)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NO1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])OC3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC([H])=NC4=C3C([H])=C([H])C4([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])C1=C(C(=O)OC2=C([H])C([H])=C([H])C([H])=C2[H])C(Cl)=C([H])C([H])=C1[H]
[H]OC1(C2=C([H])SC([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])OC(=O)N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1F)C([H])([H])C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(\C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])=C1\C([H])([H])[C@@]2([H])N([H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C(OC([H])([H])[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])C1=C2C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(\C([H])=N\OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])N2C(=C1[H])C(OC(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C(OC1=C([H])C([H])=C([H])C([H])=C21)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(=O)C([H])=C(OC2=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
CCOC1=C2C(CCC3=CC=C(C=C3)C(F)(F)F)N(CCN2C(CC)=N1)[C@@H](C(=O)NC)C1=CC=CC=C1
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)OC([H])(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
OC1=CC=C(C=C1)[B]1234[B]567[B]89%10[B]55%11[B]161[B]556[B]211[B]323[B]478[B]922[C]%10%115[C]6132
[H]N([C@]1([H])C([H])([H])OC([H])([H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)N=C1[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])N1N=NC(=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C([H])=C1OC([H])([H])[H])[C@]1([H])C([H])([H])C2([H])N(C([H])([H])C3=C([H])C([H])=C([H])O3)[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C2=NC([H])=C(C([H])=C2C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])[C@]([H])(O[H])[C@]2(C(=O)N([H])C([H])([H])[H])C([H])([H])[C@]2([H])[C@@]1([H])N1C([H])=NC2=C(N=C(Cl)N=C12)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(C#CC2=C(Cl)C([H])=C([H])C(=C2[H])C2=NN(C3=C2C([H])([H])N(C([H])([H])C3([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]([H])(O[C@@]([H])(C([H])([H])O[P@@](=O)(OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N([H])[H])N([H])C3=O)C([H])([H])[C@]1([H])O[P@](=O)(OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=C(C(=O)N([H])C2=O)C([H])([H])[H])C([H])([H])[C@]1([H])O[P@@](=O)(OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N([H])[H])N([H])C3=O)C([H])([H])[C@]1([H])O[P@@](=O)(OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N([H])[H])N([H])C3=O)C([H])([H])[C@]1([H])O[P@@](=O)(OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=C(C(=O)N([H])C2=O)C([H])([H])[H])C([H])([H])[C@]1([H])O[P@@](=O)(OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=C(C(=O)N([H])C2=O)C([H])([H])[H])C([H])([H])[C@]1([H])O[P@@](=O)(OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N([H])[H])N([H])C3=O)C([H])([H])[C@]1([H])O[P@](=O)(OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N([H])[H])N([H])C3=O)C([H])([H])[C@]1([H])O[H])N([H])[H])N([H])[H])N([H])[H])N([H])[H])N([H])[H])N([H])[H])N([H])[H])N([H])[H])C([H])([H])O[P@](=O)(O[C@@]1([H])C([H])([H])[C@@]([H])(O[C@]1([H])C([H])([H])O[P@](=O)(O[C@]1([H])C([H])([H])[C@]([H])(O[C@@]1([H])N1C([H])=NC2=C1N=C(N([H])[H])N([H])C2=O)C([H])([H])O[P@](=O)(O[C@@]1([H])C([H])([H])[C@@]([H])(O[C@]1([H])C([H])([H])O[P@](=O)(O[C@@]1([H])C([H])([H])[C@@]([H])(O[C@]1([H])C([H])([H])O[P@](=O)(O[C@@]1([H])C([H])([H])[C@@]([H])(O[C@]1([H])C([H])([H])O[P@](=O)(O[C@@]1([H])C([H])([H])[C@@]([H])(O[C@]1([H])C([H])([H])O[H])N1C([H])=NC2=C1N=C(N([H])[H])N([H])C2=O)N([H])[H])N1C([H])=NC2=C1N=C(N([H])[H])N([H])C2=O)N([H])[H])N1C([H])=C(C(=O)N([H])C1=O)C([H])([H])[H])N([H])[H])N1C([H])=C(C(=O)N([H])C1=O)C([H])([H])[H])N([H])[H])N([H])[H])N1C([H])=NC2=C1N=C(N([H])[H])N([H])C2=O)N([H])[H])N1C([H])=C([H])C(=O)N([H])C1=O
[H]N(C(=O)[C@@]([H])(N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N=C(N([H])[H])[C@]1([H])N([H])C([H])([H])C1([H])[H]
[H]N([H])C(=N/C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)\N=C(/N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)\N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
COC[C@H](C)OC1=CC(\C=C\C2=CC(F)=CC(F)=C2F)=CC(=C1)C(=O)NC1=NC=C(C=C1)C(O)=O
[H]OC([H])([H])C1=NC2=C(S1)C([H])=C([H])C(N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C(F)(F)F)N=C1[H])=C2[H]
[H]C1=C([H])C2=C(C([H])=C1Cl)C([H])([H])C([H])=C1N(C(=O)C([H])([H])C([H])([H])[C@@]21C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])=[N+](C([H])=N1)C([H])([H])[H]
[H]N(\C([H])=C1/C(=O)N([H])C(=O)C2=C([H])C([H])=C(C([H])=C12)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)S\C(=C(/[H])C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C([H])C(Br)=C2[H])C1=O
[H]N([H])C1=NC2=C(S1)C([H])=C(N([H])C1=C3C([H])=C(C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])=C([H])C3=NC([H])=C1C#N)C([H])([H])[H])C([H])=C2[H]
[H]N(C1=C2C([H])=C(N([H])C([H])([H])C3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])=C([H])C2=NC([H])=N1)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)N([H])C1=C2C(=O)C3=C(N([H])N=C3C2=C([H])C([H])=C1[H])C1=C(SC(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1=NC2=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N2[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N([H])C([H])([H])[H])C1=C([H])C2=C(C([H])=NN2S(=O)(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=NC(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1C#N)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(\N=C(/[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@@]([H])(OC([H])([H])C([H])=C([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=C1[H])C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])OC1=C([H])C(F)=C([H])C(F)=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)O[H])C1=C([H])C(C2=NC3=C([H])C(=C([H])C([H])=C3N2[H])C(=N[H])N([H])[H])=C(O[H])C(=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])O[H]
[H]N([H])S(=O)(=O)N([H])C([H])([H])C1=C([H])OC2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C([H])([H])N1C([H])([H])C([H])([H])[C@]2(O[C@@]([H])(OC2([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2[C@]([H])(N1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N([H])C1=C2C(N=C(N([H])[H])C(C#N)=C2N([H])[H])=C2C(S1)=NC(=O)C([H])([H])[C@]2([H])C1=C(F)C([H])=C([H])C([H])=C1Cl
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)[C@]1([H])C([H])([H])[C@]2([H])C([H])([H])[C@]([H])(OC(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C(F)(F)F)C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)N=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@]([H])(OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NN=C(SC([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(C(=NC2=C1C([H])=C([H])C(=C2[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[S@](=O)C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(=O)C([H])([H])F
[H]O\N=C(/[H])C1=C(Cl)C(OC2=C1C1=C(C([H])=C([H])C(=O)O1)C([H])=C2[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(SC2=C(N(OC2=O)C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])[C@@]([H])(N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])C3=C(C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C(Cl)N=C23)N([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=N1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@@](C2=C([H])C(O[H])=C([H])C([H])=C2[H])(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OP(=O)(O[H])C([H])(N([H])C1=C([H])C(=C([H])C([H])=N1)C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])P(=O)(O[H])O[H]
[H]N(N1C2=C([H])C([H])=C([H])C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C(Cl)=C2[H])C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(C(=O)N(C([H])([H])[H])C([H])([H])[H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=NOC([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C(=O)N(C([H])([H])C1=C([H])OC([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])C([H])([H])[H])N([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])=O
[H]OC(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])S[C@@]([H])(C1=C([H])C(\C([H])=C(/[H])C2=NC3=C([H])C(Cl)=C([H])C([H])=C3C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C(O[H])(C([H])([H])[H])C([H])([H])[H]
[H]S\C(=N/N=C(\[H])C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[H])N([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(OC([H])([H])[C@@]2(OC3=C([H])C(=C([H])C([H])=C3N(C([H])([H])[H])C2([H])[H])N(C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(=O)N2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]2([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(F)=C(C(Cl)=C1[H])[C@]1([H])C([H])([H])N2C(=NC([H])([H])C2([H])[H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])S(=O)(=O)C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]O[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(S1)C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(O[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C(O[C@]([H])(C3=C([H])C(F)=C([H])C([H])=C3[H])C([H])([H])[H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2=C1[H])C([H])([H])C([H])([H])[C@]([H])(F)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C2=C([H])C([H])=C(Cl)C([H])=C2N1[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]N(C([H])([H])[H])[C@]1([H])C2=C([H])C(=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H])N1N=NC([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])S1)C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[C@@]2([H])N(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)C1=NO[C@@]([H])(C([H])([H])OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C2C([H])=C([H])C(=NN2N=C1[H])C1=C([H])C([H])=C([H])S1)C1([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])C2=C([H])C3=C([H])C([H])=C(N=C3C([H])=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]C1=C([H])C(=C([H])C([H])=C1N1C(=O)N2C3=C(C([H])=C(N=C13)C([H])([H])[H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]O[C@@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])N([H])C3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]ON([H])C(=O)[C@@](O[H])(C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(SC2=C1C(=NC([H])([H])C1=NN=C(N21)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C#CC([H])([H])N1C(=O)C([H])([H])OC2=C1C([H])=C(Cl)C([H])=C2[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]O\C(OC([H])([H])C([H])([H])[H])=C1\C(=NC(C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C(=O)OC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C#CC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])SC([H])([H])C(=N/OC([H])([H])[H])\C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])C3(O[H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C([H])C([H])=C2C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N1C(=O)[C@]([H])(C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@@]1([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N([H])C(=NC1=NC(=C([H])S1)C1=C([H])N([H])C(=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])N([H])[H]
[H]OC1=C2O[C@@]3([H])C(=C([H])[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C(=O)N([H])[C@]([H])(C(=O)C2=NC3=C(O2)C([H])=C([H])C([H])=C3OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C1=NC(=NO1)C1=NC([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C1=NC([H])=C([H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]21[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C1=NC(=C(N21)C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=O)OC1([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)C([H])([H])C([H])([H])[C@]2([H])[C@](C(=O)OC([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=NC(SC2=C([H])C(Cl)=C(Cl)C([H])=C2[H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]O[C@@]([H])(C([H])([H])OC1=C(C([H])=C(SC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]N(C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H])C([H])([H])C([H])([H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C(Cl)C([H])=C(C([H])=N1)C(F)(F)F)C1=C([H])C(Cl)=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(OC(=O)C2=C([H])C3=C(C([H])=C2[H])N2C(=C(C(=O)C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C1[H])C(F)(F)F
[H]N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(OC1=C([H])C(C#N)=C([H])C([H])=C1[H])C2([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C1=C(N([H])C2=C([H])C([H])=NC([H])=C2[H])C(=O)C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C(C#N)C(=N1)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([O-])=O
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C(N1[H])C([H])=C(C([H])=C2[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])[C@]12[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C([H])=NC2=C(N=C(N=C12)C#N)N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C(O[C@]([H])(C2=C(Cl)C([H])=C([H])C(F)=C2Cl)C([H])([H])[H])C([H])=C(C([H])=N1)C1=C([H])N(N=C1[H])C(C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C(SC([H])([H])[H])S1)C1=C([H])SC(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@]1([H])C([H])([H])O[C@@]([H])(O[C@]1([H])C1=C(O[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H])\C1=C([H])N=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@]1([H])N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N1C([H])([H])C([H])=C(C2=C([H])C([H])=C3N([H])C([H])=C(C3=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])[C@]([H])(F)C([H])([H])N2[H])=C([H])C(O[H])=C1[H])C1=C([H])C(Br)=C([H])C(Br)=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@](=O)(O[H])O[P@](=O)(O[H])OP(=O)(O[H])O[H])[C@@]1([H])O[H])N1C([H])=C(C(=O)N([H])C1=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C(O[H])=C([H])C([H])=C2C11C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]OC1=C(Cl)C([H])=C(C2=C1N=C([H])C([H])=C2[H])[N+]([O-])=O
[H]N=C(N(N([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C(OC2=C(Cl)C([H])=C(C([H])=C2[H])[N+]([O-])=O)C(Cl)=C1[H])C([H])([H])Cl
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(OC2=NC([H])=NC3=C2C(=C([H])S3)C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C(F)=C1[H]
[H]N1C([H])([H])[C@@]2([H])C([H])([H])N(C3=NC([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N1C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(N2C(=O)C([H])=C([H])C3=C2C([H])=C(N=C3C2=C([H])C([H])=C(F)C([H])=C2F)C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]N(C1=NC([H])=NN2C([H])=C([H])C(=C12)C([H])([H])OC([H])([H])[C@]1([H])OC([H])([H])C([H])([H])N([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C(=C([H])O1)C([H])([H])C1=C([H])C2=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
COC1=CC(=CC=C1)N(C)C(=O)CN1C(=O)OC2=CC=C(C=C12)C1=CC=CC=C1
[H]SC([H])([H])C([H])([H])N([H])C(=O)C(=N\OC([H])([H])[H])\C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(Br)=C1[H]
[H]O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C2=C3N(C([H])=C2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])S(=O)(=O)N(C3=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1Cl)C1=C(C(=NO1)C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C([H])=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2N=C(SC2=C1[H])[C@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2N=C([H])SC2=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C2=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=C([H])C(OC4=C([H])C([H])=C([H])C([H])=C4[H])=C3[H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(C(F)=C1[H])C(F)(F)F)C1=C2C(=C([H])C([H])=C1[H])C([H])([H])N(C(=O)[C@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)C(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N([H])[C@]([H])(C1=C(N=C(O1)C1=C2C([H])=C([H])C(=NC2=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)C1=C(C(=O)N([H])C1=O)C1=C([H])N(C2=C1N=C([H])C([H])=C2[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])N(C(=O)C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=S)C([H])([H])[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C(=C([H])C([H])=C2[H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]