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[H]N1N=C(C2=C(C1=O)C([H])([H])C([H])([H])C([H])([H])N2[H])C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])N([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C(=C([H])[H])C2=C([H])C3=C(C([H])=C2[H])[C@]([H])(N([H])C(=O)C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N1[C@@]2([H])C(C(=O)N(C([H])([H])C3=C(Cl)C(Cl)=C([H])C([H])=C3[H])C3([H])C([H])([H])C3([H])[H])=C(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])OC3=C(F)C([H])=C([H])C(F)=C3Cl)C([H])([H])[C@@]1([H])C([H])([H])S(=O)(=O)C2([H])[H]
[H]O[C@@]1(C#CC([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])[C@@]3([H])C(=C4C(=C([H])C(=O)C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])[C@@]([H])(C3=C([H])C(=C(OC([H])([H])[H])C(=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]12C([H])([H])[H]
[H]N([H])C(=O)C1=C2N([H])[C@]3([H])C([H])([H])[N@](C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C3=C(C4=C(N3C(C([H])=C1[H])=C2[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C4=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C(C([H])=C3[H])C(=O)N([H])[H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)C2=C(F)C([H])=C([H])C3=C2C([H])=C([H])N3[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N3C([H])=C([H])C([H])=C([H])C3=N2)C(=O)N(C1=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C([H])C(Cl)=C2[C@]([H])(N1[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])C([H])=C([H])C1=C(C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C2=C(S1)N1C(=C([H])N([H])[C@@]1([H])C(=N2)N([H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C(=C([H])C([H])=C12)N1C([H])=NC([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
ON(=O)C1=C(Cl)C=CC(=C1)C1=NNC(=N1)C1=CC=NC=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NC2=C(N1C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N(C1=C(C(=O)N(C([H])([H])[H])C([H])([H])[H])C(=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C([H])C2=C1N=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(N(C3=C([H])N=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(C(F)=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(OC3=C(C#N)C([H])=NC([H])=C3C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3[H])=C([H])C([H])=C12
[H]N([H])C(=O)C1=C(N([H])[H])C2=C(N=C(N=C2S1)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N([H])N1C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])C([H])([H])C2([H])[H])=NC2=C([H])C([H])=C([H])N=C2C1=O
[H]\C(=C1\SC(=NC1=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NC2=C(N=C(C(=O)N2[C@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C2([H])C([H])([H])C2([H])[H])C([H])([H])[H])C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]N(N1C(=O)N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C(Cl)C([H])=C1[H])C1=C([H])C(=C2N=C(N=NC2=C1[H])N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(Cl)C2=C(S1)[C@@]([H])(OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3C([H])=C([H])C(F)=C([H])C3=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N([H])\N=C(\C(=O)N([H])C([H])([H])C([H])([H])SSC([H])([H])C([H])([H])N([H])C(=O)C(=N\N([H])[H])\C([H])([H])C1=C([H])C(Br)=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C(Br)=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(SC(=C2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])OC2=C(Br)C([H])=C(Br)C([H])=C2Br)=C1[H]
[H]N(C(=O)C1=NOC2=C1C([H])([H])C([H])([H])C1=C2C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]OC(=O)C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N([H])C2=NN=C(S2)C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N=C(SC2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N1C(=S)S\C(C1=O)=C1\C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC(=O)C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])C([H])([H])C1=C([H])SC(=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=NC(Cl)=NC(Cl)=N2)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])OC2=C(C([H])=C(O[H])C(O[H])=C2[H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C(=O)N2C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])N=C(N=C12)N([H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(C2=C(C([H])=C([H])C([H])=C2[H])N1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(OC([H])([H])C3=C2C([H])=C([H])C([H])=C3C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])OC1=C(N=C2C([H])=C([H])C([H])=C([H])C2=C1C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C(=O)N(C([H])=C2[H])C([H])([H])[H])[C@@]([H])(C(=O)N(C([H])([H])C2=C([H])C(=C([H])C(Cl)=C2Cl)C([H])([H])C([H])([H])OC([H])([H])[H])C2([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C2=C([H])C([H])=C(N=C12)C1=C(N=C(C(C#N)=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
CC(=O)N[C@@H](CC1=CC(F)=CC(F)=C1)[C@H](O)CNC1(CCCCC1)C1=CC=CS1
[H]OC1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])[C@]([H])(N([H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C1=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C(S2)C2=NOC(=N2)C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C(Cl)=C2[H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N([H])C(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N(C([H])([H])C2=C([H])C(N([H])C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC(=NO1)C1=C([H])N=C(S1)N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C2=C([H])N(N=C12)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C2=C3OC([H])([H])C([H])([H])C([H])([H])C3=C(N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C1C([H])=C([H])C(Cl)=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
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[H]N(C1=NC2=C(N=C([H])C(=C2[H])C(F)(F)F)N1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC([H])=NC2=C1SC([H])=C2[H]
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[H]N(C(=O)C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)N([H])C1=C([H])C(=C([H])C(Cl)=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])C([H])=NN2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])N(C2=C([H])C([H])=C([H])C([H])=C2C(=NC1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H]
[H]O[C@]1(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N1C([H])([H])C([H])([H])[C@]2(C(=O)N([H])C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C2N=C(C([H])=NC2=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C2C(=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
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[H]N([H])C1=NOC2=C1C([H])=C(C([H])=C2[H])N1N=C(C2=C1C(=O)N(C([H])=N2)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H]
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[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2C2=NC3=C(N2[H])C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
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[H]C1=C([H])C(=C([H])C([H])=C1O[C@]1([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1([H])[H])C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]ON(C(=O)N([H])C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[C@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])=C2[H])C1=C(F)C([H])=C(Cl)C([H])=C1[H]
NC(=O)C1=C(NC(=C1)C1=CC=NC(N)=N1)C1=CSC=C1
[H]OC([H])([H])C1=C([H])C([H])=C(O1)C1=NC([H])=C2N=C([H])N=C(N([H])C3=C([H])C([H])=C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C2=C1[H]
[H]N1C([H])=NC([H])([H])[C@@]11C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])=C(C#CC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC(=C(S1)C1=NOC(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C(S2)C#N)C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C([H])=C([H])C2=NC([H])=NC2=C1[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]OC1=NC2=C(N=C1O[H])C(=C([H])C(=C2[H])[N+]([O-])=O)C([H])([H])N([H])C(=O)C1=C(O[H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C1=C([H])N2C(=NC3=C2C(=O)N([H])C(=O)N3C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)C(C2=NN(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C(C1=O)C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C2(C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C1([H])[H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H]
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[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C#N
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=NN(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])I
[H]N(C(=O)C(\[H])=C(/[H])C1=C2C(=C([H])C([H])=C1[H])N(C([H])=C2C([H])([H])C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]N([H])[C@](C1=C([H])N=C([H])N1C([H])([H])[H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C2N3N=NN=C3N=C(C3=C([H])C(Cl)=C([H])C([H])=C3[H])C2=C1[H]
[H]N(C(=O)C1=C(N([H])C([H])([H])C2=NC([H])([H])C([H])([H])N2[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(N([H])C(=N1)C(F)(F)F)C1=C([H])C([H])=C(C(F)=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C(N([H])C2=C([H])C3=C(N=C([H])N(C3=O)C([H])([H])[H])C([H])=C2[H])=C1[H])C([H])([H])[H]
[H]OC1=C2OC3([H])C45C2=C(C([H])=C1[H])C([H])([H])C([H])(N(C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C4([H])[H])C51C([H])([H])C([H])([H])C3(OC([H])([H])[H])C([H])(C1([H])[H])C(O[H])(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(=NN1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])N=C(N=C1[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(C2=C(C([H])=C1[H])C(=NO2)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C(=O)C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C2=C([H])C([H])=C3OC([H])([H])C(=O)N([H])C3=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)C2=C(C1=O)C1=C(C([H])=C(OC([H])([H])[H])C3=C1N(C([H])=C3[H])C([H])([H])[H])C1=C2C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C(=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)N([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)C([H])([H])N([H])C(=O)C1([H])[H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C(=O)N(C1=C(OC([H])([H])[H])C(=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])OC1=C2N=C(C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC(=NC2=C1N=C(C([H])([H])C1=C([H])C([H])=C([H])O1)C2([H])[H])N([H])[H]
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[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC2=C3C([H])=C(SC3=C([H])N=C2[H])C(=O)N([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC(N([H])C([H])([H])[H])=C(Cl)C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1Br
[H]N([H])C(=O)C([H])([H])OC1=C([H])C(F)=C(N2C(=O)C(Br)=C(OC([H])([H])C3=C(F)C([H])=C(F)C([H])=C3[H])C([H])=C2C([H])([H])[H])C(F)=C1[H]
[H]N(C(=O)C1=C(OC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(N([H])C2=C(N([H])[C@@]([H])(C3=C([H])C(=C([H])O3)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)C2=O)C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C1=NN=C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)N1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C([H])C2=C([H])C([H])=C([H])C(OC([H])([H])C3=C([H])C(Cl)=C([H])C([H])=C3[H])=C2C([H])=C1[H]
[H]C1=NC2=C(C([H])=C1Br)C([H])([H])C([H])([H])C1=C(C([H])=C([H])C(Cl)=C1[H])[C@@]2([H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C([H])=[N+]([O-])C([H])=C2[H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N(C1=C(Cl)C(=O)C2=C(C([H])=NC([H])=C2[H])C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C(=O)N([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
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[H]OP(=O)(O[H])C([H])(C([H])([H])C1=NC([H])=C([H])S1)P(=O)(O[H])O[H]
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[H]N(C([H])([H])C1=NN(C(=C1C([H])([H])[H])C1=C([H])N=C(C(F)=C1[H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(F)C1([H])[H]
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[H]N(C(=O)C([H])([H])C#N)C1=C(Cl)C([H])=C([H])N=C1N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C(F)(F)F)C([H])([H])[H]
[H]C1=C([H])N=C(S1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N1C([H])=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C#N)C1=C([H])C(C([H])=O)=C([H])C([H])=C1N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])OC1=C([H])C(=NN1C([H])([H])[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
OB(O)[C@@H]1CCCN1C(=O)CNC(=O)C1=C(Cl)C=CC=C1Cl
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[H]N1C2=C(C([H])=C1C(F)(F)F)C([H])=C(C([H])=C2[H])C1=C([H])N=C(N=C1[H])N1C([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])[C@]1([H])C2([H])[H]
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[H]OC(=O)[C@]([H])(N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]1([H])SC([H])([H])C([H])([H])N1C(=O)C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C1=NC([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(N([H])C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C2=NC([H])=NC(=N2)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]OC(C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C2=C([H])[H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C3=C(Cl)N=C([H])C([H])=C3[H])C([H])=C21)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C2([H])[H]
[H]OC(=O)[C@@]([H])(N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])C1=C([H])C(O[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(\C([H])=C2/SC(=NC2=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C(Cl)C([H])=C1OC([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=NN([H])C(=C2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(C#CN2C([H])=NC3=C2C([H])=C([H])C([H])=C3N([H])C2([H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C1=NOC(=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(N1C([H])([H])[H])C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C(N([H])[H])C2=C(S1)N=C(C([H])=C2C([H])([H])C([H])([H])C([H])([H])[H])N1C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=C(O1)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
CCCCN1C(C)=C(C)C=C(OC2=NC3=CC=CC=C3O2)C1=O
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C(N=C1C1=C([H])C(Cl)=C(SC([H])([H])[H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(=C(N([H])C(=O)C([H])([H])[N+]2=C(C([H])=C(C([H])=C2C([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1Cl)S(=O)(=O)N([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC2=C([H])C(O[H])=C([H])C(=C2[H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C(=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(O[H])C([H])([H])N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])C([H])([H])N2C3=C([H])C([H])=C([H])C([H])=C3C3=C2C2=C(C4=C(C([H])=C([H])C(\C([H])=C(/[H])C5=NC([H])=C([H])C([H])=C5[H])=C4[H])N2C1([H])[H])C1=C3C([H])([H])N([H])C1=O
[H]N([C@]([H])(C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C(=O)[N-]S1(=O)=O)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(O[H])=C([H])C(C(=O)OC([H])([H])C([H])([H])[H])=C2O1
[H]N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=NON=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC(=O)ON1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])N=C([H])N2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(O1)C(=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1(C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C(Br)C([H])=C2[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C(=NN1C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C#C[C@@]([H])(O[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C(SC2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H])S([O-])(=O)=O
CCN1CCN(CC1)C(=O)C1CN(C(=O)C1)C1=CC=C(C=C1)C#C[C@]1(CN2CC3=C(C=C(OC)C=C3)C2=O)NC(=O)NC1=O
[H]\C(C1=C([H])N=C([H])C([H])=C1[H])=C1\C([H])([H])N2[C@]3([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]1([H])C3([H])[H]
[H]C1=C([H])C2=C(S1)C([H])([H])C([H])([H])OC21C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@@]([H])(C2=C([H])C([H])=C(F)C([H])=C2C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C([H])([H])C([H])([H])N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])[C@]([H])(N2C(=NC4=C2C([H])=C([H])C([H])=C4[H])C([H])([H])[H])C3([H])[H])C([H])([H])C([H])([H])N(\C(OC([H])(C([H])([H])[H])C([H])([H])[H])=N/C#N)C([H])([H])C1([H])[H]
[H]N(C1=NC(Cl)=C([H])N(C1=O)[C@]([H])(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(N1C([H])=NN=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C1=NC([H])=NC(=C1\C([H])=C(/[H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C1(OC([H])([H])C([H])([H])O1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=NN(C(=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C([H])([H])C([H])([H])[C@]1([H])O[C@@]([H])(C([H])([H])C([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
Cl.COC1=CC=C(CN2CCC3(CCCC4=CC=CC=C34)CC2)C=C1
[H]N(C1=NC(=O)[C@]([H])(S1)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C(=NC(OC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=N1)C(F)(F)F)S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC(=C([H])C2=NC([H])=C([H])C([H])=C12)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])SC([H])=C1[H]
[H]N([H])C1=NC([H])=C(C(=N1)N([H])[H])C([H])([H])C1=C([H])C(=C(OC([H])([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC(Cl)=C1C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1F
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]2(O[H])C(=O)C([H])([H])SC2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C(=O)C([H])=C([H])[C@]3(C([H])([H])[H])[C@@]12[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=C2C(=NN1[H])C([H])=C([H])C([H])=C2OC1=C([H])C([H])=C(F)C([H])=C1[H]
OP(O)(=O)C(F)(CC1=CC(=CN=C1)C1=CC2=C(NN=C2)C=C1)P(O)(O)=O
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[H]N(C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C2C([H])=C([H])C([H])=C([H])C2=NC(=C1C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NC(=C2C([H])=C([H])C([H])=C([H])N12)C([H])([H])N1C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H])C1=NC(=C([H])C([H])=C1[H])C(F)(F)F
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)=C1[H]
[H]C1=NC2=C(C([H])=C([H])C([H])=C2N1C1([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])N=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]N([H])C1=NN([H])C2=C1C(=C([H])C([H])=C2[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C1=NS(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C12)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])[H])C(=O)N([H])[C@@]1([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C(Cl)N=C([H])C([H])=C2[H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)C([H])([H])O[C@@]1([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=N1)S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])C2=C(N(N(C2=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]1([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])=C(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])[H]
CC1=CC(NC(=O)NC2=CC=C(OC3=CN=CC(C)=N3)C=C2)=C2C=CC=CC2=N1
[H]N(C1=C([H])C([H])=C([H])C([H])=C1C(=O)C1=C([H])N([H])C2=C1C([H])=C(F)C([H])=C2[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])N=C2C([H])=C1[H]
[H]C1=C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C(Cl)C(=C1[H])C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N(N=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(=C(N([H])C(=O)C([H])([H])N([H])C([H])([H])[H])C([H])=C1Cl)S(=O)(=O)N([H])[H]
[H]N1[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@@]1(C(=O)OC([H])([H])[H])C([H])([H])[C@@]3([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]1([H])[C@]([H])(C([H])([H])C([H])([H])OC([H])([H])[H])C3([H])[H]
[H]N(C(=O)C1=C(N(C(=C1[H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NN1C1=C([H])C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=NC(N([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])=C([H])C([H])=N1
[H]\C(=C(\[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])C([H])([H])OC([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]C1=C(OC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C#CC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(Br)SC(=C1[H])[C@]1([H])OC2=C(N=NC(SC([H])([H])[H])=N2)C2=C(C([H])=C([H])C([H])=C2[H])N1C(=O)C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1N=C([H])C2=C1N=C(N([H])[H])N1N=C(N=C21)C1=C([H])C([H])=C([H])O1
[H]OC(=O)[C@]([H])(OC1=C(C2=C(C([H])=C1C([H])([H])C([H])([H])C([H])([H])[H])C(=NO2)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(N1C([H])([H])C([H])([H])N([H])C2=C(C([H])=C([H])C(OC([H])([H])C3=C([H])C(=NC(=C3[H])C([H])([H])[H])C([H])([H])[H])=C2[H])S1(=O)=O)C([H])([H])[H]
[H]N1N=C([H])C2=C1C(=C([H])C(=C2[H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])[C@]([H])(N(C([H])([H])C([H])([H])OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C2C(=O)C([H])=C(OC2=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])=C([H])C([H])=C1C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C(OC([H])([H])[H])=C(Cl)N=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C2=NC(=C(C([H])=C2C#N)C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])O[C@@]([H])(C2=C([H])N=C([H])N2C([H])([H])[H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])C([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])C2=C(F)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])S[C@]1([H])C(=O)OC([H])([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)[C@@]1([H])[C@]2([H])C([H])([H])N(C3=C(Cl)C([H])=C([H])C([H])=N3)C([H])([H])[C@]12[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=NC([H])=C(N2N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
OC1=C(F)C=C(C=C1F)N1C=CC(=C1)C(=O)C1=CC=C(Br)C=C1F
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@]([H])(C([H])([H])S[H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]O[C@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]1([H])[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C2([H])[H]
[H]N(C(=O)C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C(=C(OC2=C([H])C3=C(N([H])C([H])=C3C([H])([H])[H])C([H])=C2[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H]
[H]N(C(=O)N([H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C(=C1[H])C1=NN=NN1C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NC(=NC(=C1[H])C1=C([H])C([H])=C(O1)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)N([H])C1=C([H])C(N([H])C2=C3C([H])=C([H])C([H])=C([H])C3=NC([H])=C2[H])=C([H])C([H])=C1[H])C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=NC(=N1)C([H])([H])N1C(=O)N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])N(C(=O)C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])[H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])C1=NC2=C([H])C([H])=C(N(C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C3=C2C1=C([H])C([H])=C3[H]
[H]O[C@]1(N2C(=NC([H])([H])C2([H])[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
CCCS(=O)(=O)N1CCN(CC1)C1(CNC(=O)C2=C(F)C=CC=C2F)CCC2(CC2)CC1
[H]OC([H])([H])C1=C(Cl)N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=NN([H])N=N2)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=S)N([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
COC1=CC=C(C=C1)C(N1CCOCC1)C1=C(O)C2=NC=CC=C2C=C1
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
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[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C([H])=C(SC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C2=C(S1)C([H])([H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])[C@@]2([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=NC([H])=C1C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)C1=C(N([H])C2=C1C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])C([H])([H])N(C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C2C([H])=C([H])C([H])=C(N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(N([H])C2=C(C([H])=C([H])C([H])=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C([H])C(OC([H])([H])[H])=C(C([H])=C2N=C1[H])C1=C(ON=C1C([H])([H])[H])C([H])([H])[H]
[H]\C(=C1\SC(=NC1=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C#N)C(=O)N([H])\N=C(/[H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])=C1OC([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@@](=O)(O[H])C([H])([H])P(=O)(O[H])O[H])[C@@]1([H])O[H])N1C([H])=C(I)C(=O)N([H])C1=O
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[C@]1([H])N(C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
CCNCC1=CC=C2N=C(C)C3=NN=C(N3C2=C1)C1=CC=CC=C1Cl
[H]OC1=C(C2=C(O[H])C(N([H])C(=O)\C(=C(/[H])\C(\[H])=C([H])/[C@]([H])(OC([H])([H])[H])[C@@]([H])(OC(=O)N([H])[H])\C(=C([H])\[C@]([H])(C([H])([H])[H])[C@@]([H])(O[H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])C([H])([H])[H])=C1[H])[N+]([H])([H])[H]
[H]N1N=C(C2=C(N(C3=C([H])C([H])=C(Br)C([H])=C23)C([H])([H])C2=C([H])C([H])=C([H])C(C#N)=C2[H])C1=O)C([H])([H])[H]
[H]OC([H])([H])C([H])([H])OC1=NC(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C(OC2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC2=NC([H])=C(Br)C([H])=N2)=N1
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[H]N(C(=O)C1=C2OC([H])([H])C([H])([H])C2=C([H])C(Cl)=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N1N=NN=C1C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]2([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C(C(=N2)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN=C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2F)N1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C(SC(=C2[H])C([H])([H])C([H])([H])N2C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(C([H])=N1)C([H])=C(C(=N2)N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
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[H]N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(N([H])C2=NC([H])=C([H])C(=N2)C2=NC([H])=C([H])S2)C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NC(=NO1)C1=C(OC([H])([H])C([H])([H])[H])N=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[P@](=O)(O[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])SC1=NC2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C([H])C(=NS1)C([H])([H])[H])C1=NC(=C([H])N2C1=NC([H])=C2C1=C([H])N([H])N=C1[H])[S@](=O)C([H])([H])[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(SC([H])=C1[H])C([H])([H])OC1=C([H])C2=C(OC([H])([H])O2)C([H])=C1Cl
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(SC([H])([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])=NN=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C2N=C([H])SC2=C1[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=O)N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C2=O)C([H])([H])C1([H])[H]
[H]C1=NC(OC([H])(C([H])([H])[H])C([H])([H])[H])=NC([H])=C1OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C(=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])\N=C(\S[H])N([H])C([H])([H])C([H])([H])C3=C([H])N([H])C4=C3C([H])=C([H])C([H])=C4[H])C(=C2[H])[N+]([O-])=O)=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(\C([H])=C2/SC(=O)N(C2=O)C([H])([H])C(=O)O[H])C([H])=C1[H]
[H]O\N=C1/C2=C(OC([H])([H])C1([H])[H])C(OC([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])=C([H])C(F)=C2[H]
[H]N=C(N([H])[H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]C1=NC([H])=C(C([H])=N1)C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])=C(C2=C1C(F)=C([H])C([H])=C2[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])[C@@]([H])([C@]1([H])N([H])C(=O)C1=C([H])SC([H])=C1[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])[C@]2([H])N(C3=NC(=C([H])C([H])=C3C2([H])[H])C([H])([H])OC([H])([H])C2([H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=C(C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)OC([H])([H])[H])C2([H])[H]
[H]OP(=O)(O[H])OC([H])([H])[C@@]1([H])[C@@]([H])(OP(=O)(O[H])O[H])C([H])([H])[C@@]1([H])N1C([H])=NC2=C1N=C(Cl)N=C2N([H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C2=NN=C3SC([H])([H])C(=NN23)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(OC([H])([H])C([H])([H])[H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(=O)C1=NC([H])=C([H])S1)N([H])[H]
[H]C1=C([H])C(N2N=C3C(=C2C([H])([H])[H])C(=NN=C3N2C([H])([H])C([H])(OC([H])([H])[H])C2([H])[H])C([H])([H])[H])=C(F)C([H])=C1OC([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)OC1=C([H])C2=C(C([H])=C1[N+]([O-])=O)[C@@]1([H])C([H])([H])C([H])([H])[C@@]3(C(=O)C([H])([H])C([H])([H])[C@@]3([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N([H])C(=O)N([H])C1=C2C(=O)C3=C(N([H])N=C3C2=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])N=C(S2)C2=C(Cl)C([H])=C(O[H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])C([H])([H])[H])C([H])([H])N([H])[C@]([H])(C([H])([H])N([H])[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])[C@@]([H])(C([H])([H])N([H])[C@]([H])(C([H])([H])N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]C1=C(ON=C1OC([H])([H])C#CC([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])[C@@]2([H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N(C(=O)C1=C([H])C([H])=C2N(C3=C(C2=C1[H])C([H])([H])[C@@]([H])(C([H])([H])C3([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C2N([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C(N2N=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C(OC([H])([H])[H])=C(F)C([H])=C1[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=NC(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])N([H])[C@@]([H])(C([H])([H])[H])C1([H])[H])C1=NC([H])=C(SC([H])([H])C2=NC([H])=C(O2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S1
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC(=C([H])N=C2N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(Cl)C([H])=C(Cl)C(=C1[H])C1=C2N=C(N=C(N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])C2=NN1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(\C#N)=C(/[H])C1=C([H])C(\C([H])=C(/C#N)C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N([H])C5(C6=C([H])C([H])=C(Cl)C([H])=C6[H])C([H])([H])C([H])([H])C([H])([H])C5([H])[H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C([H])([H])[N@@+]12C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])[C@@]1(ON=C(Br)C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])N1C(=O)C(Br)=C(OC([H])([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C([H])([H])C1(OC([H])([H])C2=C(C3=C(S2)C2=NN=NN2C2=NN=NN32)C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])N2N=C([H])N=C(N([H])C3=C([H])C([H])=C4N(N=C([H])C4=C3[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2=C1C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(N2[C@]2([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]([H])(O[H])[C@]2([H])O[H])C2=C(C3=C(N2[H])C(O[H])=C([H])C([H])=C3[H])C2=C1C(=O)N(N([H])C([H])(C([H])([H])O[H])C([H])([H])O[H])C2=O
[H]N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C(SC([H])([H])[H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])[H]
[H]N(C(=O)C([H])([H])[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])[C@@]2(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])[C@@]3([H])[C@@]([H])(OC(=O)[C@@]3([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]23[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1(C([H])=O)C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C([H])=C([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])N=C([H])N1[H]
[H]N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(F)C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])O1)C([H])([H])N1C(=O)[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C3=C(C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O\C(OC([H])([H])C([H])([H])[H])=C1\C(=NC(=C(C(=O)OC([H])([H])[H])[C@]1([H])C1=C([H])C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C(S1)C1=NN=C2SC3=C(N=C4C([H])=C([H])C([H])=C([H])C4=N3)N([H])N12)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)C1=C([H])C([H])=C(I)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])C4=C(C5=C(N4[H])[C@]4([H])OC6=C(O[H])C([H])=C([H])C7=C6[C@@]44C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])[C@]([H])(C7([H])[H])[C@]4(O[H])C5([H])[H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]N(C1=C([H])C([H])=C(F)C([H])=C1C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1(C(=O)N([H])C(=O)N([H])C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NO[C@@](C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])(C([H])([H])N2N=NN=C2[H])C1([H])[H]
[H]OC(=O)C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1C(=O)O[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]C1=C(N(N=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
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[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C(C([H])=C1[H])C1=C([H])OC([H])=C1[H]
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[H]N(C1=C([H])C([H])=C([H])N2N=C(N=C12)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)C([H])([H])[H]
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[H]C1=C(C(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])=C2O1)C1=C([H])N=C(C([H])=C1[H])N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
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[H]N([H])C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]C1=C([H])C(=C(C(=C1[H])N1N=C([H])C(Cl)=C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1=O)C([H])([H])[H])C([H])([H])[H]
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[H]N1C(=O)N2N=C(C(=O)OC([H])([H])[H])C([H])([H])[C@]2([H])C2=C([H])C(Cl)=C(Cl)C([H])=C12
[H]OC(=O)[C@]([H])(N1C(=O)N2N(C1=O)[C@@]([H])(C([H])=C([H])C2([H])[H])C(=O)N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1([H])[H])C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)O[C@]1([H])[C@]([H])(C2=C(F)C(=C(F)C([H])=C2N([H])C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1N([H])C([H])=C2Cl)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H]
[H]OC1=NC2=C(C([H])=C(Cl)C([H])=C2[H])N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]([H])(O[H])C([H])([H])N2N=C(C3=C2C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C3([H])[H])C2=C([H])C(=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C([H])([H])C1=C(C(=O)ON1C(=O)N1C([H])([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C2C(=C1[H])[C@@]1([H])N(C([H])([H])C3=C(C([H])=C(C([H])=C3C([H])([H])[H])C([H])([H])[H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N1C(=O)[C@]2(N(C(=O)[C@]1([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]C1=NN=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])[C@]1([H])F
[H]N1N=C(C2=C([H])C(C#N)=C([H])C([H])=C12)[C@]1([H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]1(SC(=NC1=O)N([H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)O[C@]1([H])[C@]([H])(C2=C(F)C(=C(F)C([H])=C2N([H])C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1N([H])C([H])=C2[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])OC(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(OC([H])([H])C([H])([H])C2=C([H])N(C4=C2C([H])=C([H])C([H])=C4[H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C(Cl)=C(F)C(=C1[H])C1=NC([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C12
[H]C1=C([H])C2=C(C([H])=C([H])C(OS(=O)(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])=C2[H])N1C([H])([H])[H]
[H]C1=C(O[C@@]2([H])C(=O)C([H])([H])C([H])([H])C2([H])[H])C(=C2OC(=O)C([H])=C(C2=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2C([H])=NC([H])=C([H])C2=NC(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])[H])=C1C#N
[H]N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])N(C(=O)[C@@]([H])(OC1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C(N([H])C(=O)C2=C([H])C(=NN2C2=C(C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(OC([H])([H])[H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=NC(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N1N=C(N(\N=C(/[H])C2=C([H])C([H])=C(S2)C([H])([H])[H])C1=S)C1=C([H])C([H])=C([H])O1
[H]N([H])[C@]1([H])C2=C([H])C(=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C(=C(/[H])C1=C([H])N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])\C([H])([H])C1=C([H])C([H])=C([H])S1
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C2N=C(C([H])=C(C2=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(OC(F)(F)F)C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])N(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NSC4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C(=O)C([H])([H])[C@]2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)N(C(=C(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C1=O)C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]OC(=O)[C@@]([H])(OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C1=C(N(C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C12)C1=NC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(N(N=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N1C(OC([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)=NC2=C(C1=O)C(=C([H])C(=O)O2)C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(N=C([H])N=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])=NC(=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1C(=O)N2C3=C(C([H])=C(N=C13)C([H])([H])[H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C(C#N)=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]1([H])OC(=O)\C(=C(/N([H])C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O
[H]C1=C([H])C2=C(C([H])=C1[H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=N/OC([H])([H])C([H])([H])N([H])[H])\C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1N([H])C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
C=CC(=O)NC1=CC=C(C=C1)S(=O)(=O)N1CCNCC1
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C2C([H])=C(N([H])C2=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([3H])([3H])C([3H])([3H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(F)(F)F)C1(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])C([H])([H])[C@]2(C([H])([H])OC([H])([H])[H])C1([H])[H]
[H]N(C1=NC2=C(C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C(=N1)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2N([H])C(=C([H])C2=C1C([H])([H])[H])C([H])([H])[H])C1=C(C#N)C([H])=NC([H])=C1\C([H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])OC21C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C1=C(N2C([H])([H])C([H])([H])N(C(=O)[C@]3([H])C([H])([H])OC([H])([H])[C@]3([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C(F)=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C2O[C@@]([H])(N([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC(=C([H])C(=N1)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(C#N)=C([H])C([H])=C2N1C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(N2C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N(C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])[C@](C(=O)N(C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N1C(=NC2=C1C([H])=C([H])C(=C2[H])C(=O)N1C([H])([H])C([H])([H])C2(OC3=C(C(OC([H])([H])[H])=C([H])C([H])=C3[H])C(=O)C2([H])[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]C1=C(C(=O)C2=C([H])C([H])=C(C([H])=C2O1)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])N=C(C([H])=C1[H])N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)C1(N([H])C(=O)C2=C([H])C3=C(N(C2=O)C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C#CC([H])([H])[H])C1=C([H])N=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]N=C(N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])C1=N[C@]([H])(N(C(=N1)N([H])[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2O[C@@]1([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N(C(=O)C1=NC(=NO1)C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(Br)C([H])=C1OC([H])([H])[H]
[H]N([C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C(Cl)C([H])=C2C([H])=C1[H]
[H]C1=C2N(C(=O)C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])[C@@]3([H])[C@]2([H])[C@@]1([H])C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C(=NC([H])=C1N(C(=O)C(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C2C(=O)N([H])C(=O)C(=O)C2=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(I)C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
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C[C@H](NC(=O)C1(N)CCN(CC1)C1=NC=NC2=C1C=CN2)C1=CC=C(Cl)C=C1
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[H]O[C@]([H])(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N1C(=O)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])N1N=C(Cl)C([H])([H])C([H])([H])C1=O)C(=O)[C@@]([H])(C(=O)N2C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])N3C(=O)N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]4([H])C3=O)C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]O[C@@]([H])([C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])SC([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])P(=O)(OC([H])([H])C([H])([H])[H])OC([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])ON([H])C(=O)C1=C(N([H])C2=C([H])C([H])=C(C#C[H])C([H])=C2F)C(F)=C(F)C(=C1[H])C([H])([H])N1OC([H])([H])C([H])([H])C1=O
[H]OC(=O)C1=C(N([H])C(=O)N([H])[C@@]1([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])OC2=C3C([H])=C([H])C([H])=C([H])C3=NC(=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])=C(O2)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(N=C(N(C2=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C(SC(=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C([H])C([H])=C(Cl)C([H])=C2N1C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=NO[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C2=NC([H])=C([H])N2[H])C1([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])N([H])C3=C([H])C([H])=C(F)C([H])=C23)C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(S1)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])N([H])[C@@]1([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC(N([H])C2=C(C([H])=C([H])C([H])=C2[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=N1)C1=C(OC([H])([H])[H])C2=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C(OC1=C([H])C2=C(C([H])=C1[H])C(=NO2)C([H])([H])C([H])([H])C1=C(OC(=N1)C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2=C1[H]
[H]C1=C(N=C2C([H])=C([H])C(I)=C([H])N12)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)C1=C(OC(=C([H])C1=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(N([H])C([H])=C1C([H])([H])[H])C(\[H])=C1/C(=O)N([H])C2=C([H])C(=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N(C2=NC3=C([H])C([H])=C([H])C([H])=C3C(=C2C1=O)C([H])([H])[H])C([H])([H])C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C(N=C(SC2=NC3=C(N2C([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])C(C#N)=C1C([H])([H])OC([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=NC2=C1N=C([H])O2)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C2=C([H])C([H])=C(N=C12)C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N([H])C1=NC(=C(N1[H])C([H])([H])[H])C([H])([H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(C(=O)N([H])[C@@]1([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C2C(O[C@]([H])(C3=C([H])C(O[H])=C(O[H])C(O[H])=C3[H])[C@]([H])(OC(=O)C3=C([H])C(O[H])=C(O[H])C(O[H])=C3[H])C2([H])[H])=C1[H]
[H]C1=C([H])C([H])=C2N=C(OC2=C1[H])SC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])C1=C(ON=C1N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]C1=C([H])C(=C([H])C(C#N)=C1[H])C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(N([H])C2=NSN=C2N([H])[C@@]([H])(C2=C([H])C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C3([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C(Br)C([H])=C([H])C([H])=C1[H]
CCCC1=C(C(=O)OCC)C(C(=O)OCC)=C2N1N=C(C=C2C1CCCCC1)N1CCOCC1
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=S)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1=C(SC2=C1C(=O)C(=C([H])N2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C(N=C([H])S1)C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]O[C@@](C1=C([H])N([H])C([H])=N1)(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])[H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1(C(=O)OC([H])([H])C2=C1C([H])=C1N(C2=O)C([H])([H])C2=C(C3=C([H])C(OC(=O)N4C([H])([H])C([H])([H])C([H])(N5C([H])([H])C([H])([H])C([H])([H])C([H])([H])C5([H])[H])C([H])([H])C4([H])[H])=C([H])C([H])=C3N=C12)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C1=NC2=C([H])C([H])=C([H])N=C2N([H])C2=C1C([H])=C(Cl)C([H])=C2[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N([H])C1=C2C([H])=C(SC2=C(C([H])=N1)C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2N(C([H])=C(C2=C1[H])C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N([H])C1=NN=C(S1)C1=C([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C(=O)C1=C(N([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C3=C(N=C([H])C([H])=C3[H])N([H])[H])C([H])=C21)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C(=O)C(C2=C([H])C(=NO2)C([H])([H])[H])=C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(Cl)=C([H])C([H])=C12
[H]N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N2C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])[C@]([H])(OC(=O)[C@@]1([H])N(C(=O)[C@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])C(=O)[C@]1([H])N(C(=O)C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@](C([H])([H])[H])(C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])N(C(=O)C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C(=O)N([H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C(F)=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=NC(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)SC3(C2=O)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])O[C@@]1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@@]1([H])N([H])C1=C(N=C(OC2=C([H])C(=C([H])C([H])=N2)C([H])([H])[H])C(=N1)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2N2C1=NN=C2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)[C@]([H])(N([H])[H])C([H])([H])N([H])C(=O)OC([H])([H])C1=C(Br)C([H])=C([H])C([H])=C1[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]N([H])C(=O)C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(N=C1[H])C([H])=C(C([H])=C2[H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])O1)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=NC(=NO1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])C(=O)C3=C([H])C([H])=C([H])O3)C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1F)C([H])([H])[H]
[H]N1C([H])=C2C3=C(C([H])=C([H])N=C13)C1=C(N([H])[C@@]2([H])C([H])([H])OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=C(OC)C=C(CCN(C)CCC[C@]2(CCC3=C2C=CC(OC)=C3OC)C#N)C=C1
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])O[C@]1([H])C([H])=C([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=NN(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C(=NN12)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C(N=C(SC([H])([H])[H])N=C1SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)C1=C([H])C([H])=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C(N([H])C2=NC([H])=NC(=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]
CC1=C(Cl)C=CC(=C1)C1CNCC=CC1
CC(C)OC(=O)C1=CC(O)=C(O)C=C1
[H]N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C3N(N=C([H])N=C3N([H])C3=C([H])C([H])=C([H])C(Br)=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=NC(=N2)C([H])([H])[H])N([H])C2=C([H])C(=NN2[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N([H])C(=O)OC([H])([H])C2=NOC(=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(ON=C1C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C([H])C(=C1[H])C1=C([H])N=C(S1)N([H])C1=NC([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C(F)(F)F
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C([H])C3=C(N(N=C3C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)S(=O)(=O)C1=C(Cl)C([H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)N([H])[C@@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OS(=O)(=O)C([H])([H])C([H])([H])C([H])([H])N1\C(SC2=C([H])C([H])=C([H])C([H])=C12)=C1\SC(=S)N(N([H])[H])C1=O
[H]N(\N=C(/[H])[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C(S1)C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C(\[H])=C(/[H])C3=C(F)C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(Br)C([H])=C2C(=NN([H])C2=C1[H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C(S1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]OC1=C(C([H])=C(Br)C([H])=C1Br)C([H])([H])N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@@]1([H])[C@]([H])(N(C([H])([H])C2=C([H])N([H])C([H])=N2)S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])C2=C([H])C(=C([H])C([H])=C2OC1(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C([H])=C1Br)C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C(C#N)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])C1=C(N(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C#N)C2=C([H])SC([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])N(N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CN1C(C)=C(C(=O)N(C)C1=O)C1=CC=C(C[C@H](NC(=O)C2=C(Cl)C=CC=C2C)C(O)=O)C=C1C
[H]OC1=C([H])C(\C([H])=C(/C#N)C(N([H])[H])=C(C#N)C#N)=C([H])C(O[H])=C1O[H]
[H]N([H])C1=NC2=C(S1)C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]1(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C(C(Br)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])N([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2Cl)[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
COC1=CC2=C(CN(C[C@]3(NC(=O)NC3=O)C#CC3=CC=C(N=C3)C3=CC=C(F)C=C3O)C2=O)C=C1
[H]N1C([H])=C(C([H])=O)C2=C1C1=C(C([H])=C2[H])C2=C(N1[H])C([H])=C([H])C(=C2[H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]N(C1=NC(=C([H])C([H])=N1)N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])C(Br)=C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1=O
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[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C(OC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]S\C(=N/N=C(/C1=C([H])C(Br)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])C([H])(OC2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C2=C([H])C(OC(F)(F)F)=C([H])C([H])=C2C(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]ON(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=NC2=C(C([H])=C1[H])C([H])=C(C([H])=C2[H])C([H])([H])OC1=C([H])C(=C([H])C(F)=C1[H])C1(OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H]
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[H]O[C@]([H])(C1=C([H])SC(=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])C([H])=C(OC2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1F
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC3=C(N2C([H])([H])C#CC([H])([H])[H])C(=O)N(N=C3[H])C([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=C(C#N)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]O\N=C1\C(\N([H])C2=C\1C([H])=C([H])C([H])=C2[H])=C1\C(=O)N([H])C2=C([H])C(Cl)=C(Cl)C([H])=C12
[H]OC(=O)C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])[C@]([H])(O[H])C([H])([H])[C@]4([H])C([H])([H])[C@@]([H])(OC([H])([H])C([H])([H])N(C5=C([H])C([H])=C(C([H])=C5[H])[C@]5([H])C6=C7C(=C([H])C(=O)C([H])([H])C7([H])[H])C([H])([H])C([H])([H])[C@@]6([H])[C@]6([H])C([H])([H])C([H])([H])[C@@](O[H])(C#C[H])[C@@]6(C([H])([H])[H])C5([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])[C@]([H])(O[H])[C@]12C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C([H])=C(Cl)C(=C2[H])C([H])([H])C2=NN=C(S2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C(=C(Cl)C([H])=C1Cl)C1=C(C([H])=C([H])C2=C(C([H])=C(N=C12)C([H])([H])[H])N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C2N=C(C([H])=C(N2N=C1SC([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]C1=C([H])C(=C([H])C(OC2=C(OC(=C([H])C2=O)C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1[H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(O[H])C(O[H])=C1[H]
[H]OC(=O)C1=C(F)C([H])=C(N([H])C(=O)C2=C([H])C3=C(C(Br)=C2O[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)N([H])[C@]2(C1=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1S(=O)(=O)C([H])([H])C2([H])[H]