[H]N(N1C(SC([H])([H])SC2=NN=C(N2N([H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])SC(=N2)N([H])C(=O)C([H])([H])[H])=NN=C1C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C([H])([H])[H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C(=O)N(C(=O)C2=C1C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1C1=C2C([H])=C([H])C(=O)C([H])=C2OC2=C([H])C(O[H])=C([H])C([H])=C12)C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1N=NC(=C1[H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N2C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
C[C@@H](NC(=O)C1=CNC2=NC=C(N=C12)C1CC1)C(=O)N1CC(C1)C#N
[H]C1=C([H])C(=C([H])C(OC([H])([H])C2=C([H])C3=C(C([H])=C2[H])N(C(=O)C([H])=C3[H])C([H])([H])[H])=C1[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(=O)[C@]2(C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N1C(=NC(C2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C2C(OC(C([H])([H])[H])(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])=C([H])C(=C1[H])C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])Br
[H]ON([H])C(=O)[C@@]([H])(O[H])C([H])([H])N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C(C([H])=C(O[H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CCn1cc(cc1C(=O)N[C@H](CO)c1cccc(Cl)c1)-c1nc(NCC(F)(F)F)ncc1C
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C#CC([H])([H])N(C(=O)[C@@]1(C2=C([H])C([H])=C3OC([H])([H])C([H])([H])OC3=C2[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[C@]1(O[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)OC([H])([H])[C@]12OC(O[C@@]1([H])[C@]1([H])OS(=O)(=O)O[C@]1([H])C([H])([H])O2)(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]C1=C(C(N2C3=NC(=C(N3C([H])([H])C([H])([H])C2([H])[H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C(F)(F)F)C(F)(F)F)=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])[P@@](=O)(O[H])C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C1=C(N([H])N=C1O[C@]1([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]1([H])O[H])C(F)(F)F
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)C(=NC2=C([H])C([H])=C(N=C12)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])N=C(C([H])=C1[H])N(C1=C([H])C(OC([H])([H])C(=C([H])[H])C([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C(C(=O)N([H])C2=C(F)C([H])=C(C([H])=C2F)C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])[C@]1([H])N=C(C2=NC([H])=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N(C1=O)C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]O[C@]1([H])\C(=C([H])\[C@]([H])(C(=O)C([H])([H])[C@@]([H])(OC(=O)[C@@]2([H])N(C(=O)C(=O)[C@]3(O[H])O[C@@]([H])(C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])[H])C([H])([H])[C@]([H])(OC([H])([H])[H])\C(=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C([H])\[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)[C@]1([H])OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(OC(=O)N(OC([H])([H])[H])C([H])([H])[H])[C@]([H])(OC([H])([H])[H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C(N=C(S1)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C(\C([H])=C(/[H])C2=C([H])N=C([H])C([H])=C2[H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(C(=C1C(=O)C([H])([H])SC1=NN=C(N1C1=C([H])C([H])=C([H])C([H])=C1F)C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])O1)[C@]1([H])C(=O)[C@@]2([H])O[C@@]22[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])[C@]3(C([H])=C([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]21C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C2OC([H])=C([H])C2=C(C2=C1C([H])=C([H])O2)C([H])([H])C1=NC(=NO1)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C(=C23)C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N1C([H])([H])C(=C([H])C([H])([H])C1([H])[H])C1=NN(N=C1[H])C([H])([H])[H]
[H]N([C@]1([H])C(=O)N(C([H])([H])C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])S(=O)(=O)C1=NC2=C(S1)C([H])=C([H])C(Cl)=C2[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])=C([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C2C([H])=C(N([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C3=C(S2)C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1Cl)C(=O)N([H])\N=C(/[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C(O2)C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])=C1OC([H])([H])[H]
[H]C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
CC1=CC=C(CC2=CC=NC(COC3=CC=C(C)C=C3)=C2)C=C1
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3C([H])=C(F)C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)C(\[H])=C(/[H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2C1([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])O[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@@](=O)(O[H])O[P@](=O)(O[H])OP(=O)(O[H])O[H])[C@@]1([H])O[H])N1C([H])=C([H])C2=C(C([H])=C(Cl)C(Cl)=C2[H])C1=O
[H]OC1(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C(=O)N([H])C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2C([H])([H])C([H])([H])N([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])C(=N\C(=O)C([H])([H])N1C(=C([H])C([H])=C1[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])\N([H])C([H])([H])C1=C([H])C([H])=C([H])C(N([H])[H])=C1[H]
[H]N(\C(=N/C#N)N([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C3=NOC(=N3)C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(F)=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C2OC([H])([H])C([H])([H])C2=C([H])C(=C1[H])C1=NN=C(O1)SC([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(Br)=C(C([H])=C1OC([H])([H])[H])C([H])([H])N([H])C(=S)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C2=C([H])C([H])=C(Cl)S2)C1([H])[H])C1=C([H])C([H])=C(C([H])=C1F)N1C([H])=C([H])C([H])=C([H])C1=O
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1([H])C([H])=C(C2=C([H])C(F)=C([H])C([H])=C2F)C([H])([H])N1C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])O[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1([H])[H]
[H]N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@]1(N2C(=NC([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(OC([H])([H])C([H])=C([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(Br)=C2C([H])=C([H])C([H])=C([H])C2=C1OC([H])([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N(C(=O)C1=C(N([H])C(\C([H])=C2/C(=O)N([H])C3=C([H])C([H])=C(F)C([H])=C23)=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1N=C(SC([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(OC2=NC(OC3=C([H])C([H])=C4OC([H])([H])OC4=C3[H])=NC([H])=C2[H])C([H])=C1[H]
[H]N([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C(OC([H])([H])[H])=C(N([H])C3=NC([H])=C(Cl)C(=N3)C3=C([H])N=C4C([H])=C([H])C([H])=C([H])N34)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(\C([H])=C(/[H])C([H])=O)=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])=C([H])[H])=C1O[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=NN1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C(Cl)=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(S1)S(=O)(=O)N1C2=C([H])C([H])=C([H])C([H])=C2[C@@]([H])(C(=O)N(C([H])([H])[H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(OC3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])=NC([H])=C2S1
[H]OC1=C([H])N=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O\N=C(\C(=O)N([H])C([H])([H])C([H])([H])S[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]OC1=C(C([H])=C2C([H])=C([H])C3=C(N([H])C4=C([H])C([H])=C([H])C([H])=C34)C2=C1[H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=C(C([H])=O)C2=C1C([H])=C([H])C1=C2C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H][C@@]12C[C@H](OC(=O)C3=CC=CC(SC)=C3)[C@@]3(C)OC4=C([C@H](O)[C@]3([H])[C@@]1(C)CC[C@H](OC(C)=O)[C@@]2(C)COC(C)=O)C(=O)OC(=C4)C1=CN=CC=C1
[H]OC1=C([H])C(=C([H])C(OC2=C(F)C(=C(F)C(OC3=C([H])C(=C([H])C([H])=C3[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])=N2)C([H])([H])[H])=C1OC([H])([H])[H])C(=N[H])N([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C3=C(C([H])=C2[H])N(C(=O)S3)C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N([H])C1=C([H])C([H])=C(N([H])C2=NC(=C([H])S2)C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])=NC(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)C([H])([H])[H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)C([H])([H])OC2=C([H])C([H])=C(C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(\C([H])=C(/[H])N([H])C([H])=O)=C(O[H])C([H])=C1[H]
[H]C1=C([H])C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(OC([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])C3([H])[H])C3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
CN1CC[C@@H](C1)OC1=C(C=CC(NCC2=CC3=C(OCO3)C=C2Br)=C1)C(F)(F)F
[H]N1C(=O)C(C2=C([H])C(C3=C([H])C([H])=C(C#N)N3C([H])([H])[H])=C(F)C([H])=C12)(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(N([H])C(=N1)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N([C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(F)=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])N(N=C1C(F)(F)F)C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C(Br)C([H])=C2[H])C([H])([H])C([H])([H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C(=O)N1C1=C([H])C([H])=C([H])C(=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(N([H])C(=O)C4=C([H])C(=C([H])C([H])=C4[H])C(F)(F)F)C([H])([H])C([H])([H])[C@@]3([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])C3([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@]1([H])C([H])([H])O[C@]([H])(O[C@@]1([H])C1=C([H])N=C([H])C([H])=C1[H])C(OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(N=N2)C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C(N=C3[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=NC(=NN2C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H]
[H]OC1=C2C(=C3C(N=C(N=C3N([H])[H])N([H])[H])=N1)C([H])([H])C([H])([H])N(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C2([H])[H]
[H]OC1=C(C#N)C2=C(C(SC([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])S(=O)(=O)C([H])([H])[H])=N1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1(OC([H])([H])C2=C(N=C(N=C12)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])[C@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])N([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])N=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C#CC2=NC(Cl)=NC([H])=C2[H])C([H])=C1[H]
[H]O[C@]1(C([H])([H])[H])[C@@]([H])(OC(=O)C2=C([H])C([H])=C([H])N=C2[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]2(C([H])([H])[H])[C@@]([H])(OC(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]3([H])C([H])([H])[C@]12OC3(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]