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[H]N(C([H])([H])C1=C(N=C2N1C(=O)C(C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])=C(N2C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N1C(=O)C2=C(N(C(=O)N([H])[C@]2([H])C2=C([H])C([H])=C([H])C(=C12)[N+]([O-])=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C(=O)O[C@@]1(C([H])([H])[H])C([H])([H])C(F)(F)F)S(=O)(=O)C([H])([H])[H]
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[H]N(C1=NOC2=C([H])C(=C([H])C([H])=C12)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N1C2=NC([H])=C([H])N=C2C([H])=C1C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C(=NC2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])N(C([H])([H])[H])C([H])([H])[H]
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[H]O[C@@](C1=NC2=C([H])C(Cl)=C(Cl)C([H])=C2N1[H])(C([H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C(F)C([H])=C1F
CC1=CC(=CC=C1)C(C1=CN=CC=C1)C1=CC2=C3N(CCC3=C1)C(=O)CC2
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])O[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])C1=C([H])C(OC([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C(C(OC([H])([H])C(=O)O[H])=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C(C(OC([H])([H])C(=O)O[H])=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])[H]
CN(C(=O)C1=CC2=C(S1)C1=NC=CC=C1OCC2)C1=CC=CC=C1Cl
[H]C1=C2C([H])=C([H])C([H])=C(C2=NN1[N+]([O-])=O)[N+]([O-])=O
[H]OC1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C(OC([H])([H])[H])=C2[H])C2=NC3=C(C(=NS3)C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(=O)N2[H])C([H])([H])C1([H])[H]
[H]C1=C(N(N=C1C([H])([H])[H])C1=NC(=NC(=N1)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])[C@]1([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N2C([H])=C([H])N=C2C(=N1)N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC([H])([H])C(=O)N([H])[C@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(SC([H])([H])C2=NC(=C(S2)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]C1=C(C#N)N(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C2C(=O)N(C([H])([H])OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])S(=O)(=O)C2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(N([H])C(=N[H])N([H])[H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=C([H])C([H])=C2N([H])N=C(C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H]
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[H]ON([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])O2)C([H])([H])[C@]1([H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H]
[H]ON1C([H])=C([H])C([H])=C(C1=O)C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
[H]N([H])[C@]([H])(C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)N(C1=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(\C(=C1/C(=O)N([H])C2=C([H])C(=C([H])C([H])=C12)C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C2C([H])=C([H])C(C([H])=C2SC2=C3C4=C(C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C3([H])[H])=[N+](C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)S[C@@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C([H])=N2)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N(C1=NC2=C(S1)C([H])=C(Br)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(C(=O)C(C2=C([H])C([H])=C(F)C([H])=C2[H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C([H])=C([H])C(=C1[H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]\C(=N/N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N1N=C(C2=NC3=C(N2[H])C([H])=C([H])C(=C3[H])N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C(OC([H])([H])[H])C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C2[H]
[H]O[C@]([H])(C([H])([H])C1([H])C([H])([H])C(=O)N([H])C(=O)C1([H])[H])[C@]1([H])C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])[C@@]2(C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])C#N
[H]N1C(=O)C2=C(C1=O)C1=C([H])N(C3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])N1C([H])=C2C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C1=C([H])C([H])=C(C([H])=C1C#N)C1=C([H])C2=NC(=C([H])C([H])=C2C([H])=C1[H])C([H])([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C2(C(=O)N([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]OC([H])([H])C([H])([H])N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(Br)=C([H])C(OC([H])([H])[H])=C1OC([H])([H])C([H])([H])F)C([H])([H])C(\[H])=C(/[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
COC(=O)C1=CC=C(C=C1)C1=CSC2=C1OC(=CC2=O)N1CCOCC1
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC([H])=NC(OC([H])([H])[H])=C1[N+]([O-])=O
[H]O[C@]([H])(C([H])([H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C3=C([H])C([H])=C([H])C([H])=C3N(C1=O)C([H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C2C([H])=C(C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C1[H]
[H]OC([H])([H])C1=C([H])N=C([H])C(=C1[H])C([H])([H])N1C(=C(C#N)C(=C1C([H])([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C(O[H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C1=C([H])C(N([H])[H])=C(SC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N([H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C3=C(C([H])=C4C([H])=C([H])C([H])=C([H])C4=N3)C([H])([H])[C@@]12[H]
OC1=CC=CC(\C=C\C(=O)NCC2=CC=CC=C2)=C1
[H]OC([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(C2=NN=C3C([H])=C([H])C(SC4=C([H])C([H])=C(F)C([H])=C4F)=C([H])N23)C(=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])C([H])([H])C([H])=C([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(=C([H])C2=C1C([H])=C(F)C([H])=C2[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2[C@@]2(C1([H])[H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)C(N([H])C(=O)C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(C(=O)N([H])[H])=C(N=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
CC(C)C[C@H](CO)NC1=NC(S[C@@H](C)C2=NC=CC(Cl)=C2)=NC2=C1SC(=O)N2
[H]N(C([H])([H])[H])[C@]1([H])C2=C([H])C(=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)N([H])C([H])([H])[H]
[H]C1=C(OC([H])([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])N(N=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=C1[H])C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])OC1=C([H])C(F)=C([H])C(F)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])OC([H])([H])[C@]2(O1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N1C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C2=C1C([H])([H])N([H])C([H])([H])C2([H])[H]
NCC[C@H](N)C(=O)N1CCC[C@@H]1B(O)O
[H]\C(=C(\[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])C([H])([H])F)C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
CNC(=O)C1=CC2=C(CCC3=C(C=CC(NC4=C(F)C=C(F)C=C4)=C3)C2=O)C=C1
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=C(N([H])C(C#N)=C2C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC(F)(F)F)C(=C1[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C1=C2C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C2=NC(=C([H])S2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[N@@+]12C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])[C@@]([H])(OC(=O)[C@@](N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C2([H])[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C(N=C2C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]C([H])([H])[C@@]1([H])C(=O)C([H])([H])C([H])([H])[C@]2([H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]3([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C(F)(F)F
[H]OC(=O)[C@@]1([H])[C@@]([H])(N(C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(O[H])C(=C1[H])C([H])([H])N([H])C1=C([H])C([H])=C(O[H])C(=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1C(=C([H])C2=C1C(=C([H])C([H])=C2[H])C1=C([H])C(=C2N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]([H])(C2=C1Cl)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[S@+]([O-])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=C3C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])C(=O)N([H])C1=NOC(=C1[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])[C@@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C2=C1N([H])C1=C([H])C([H])=C(Cl)C([H])=C21
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])=C1Br)[C@@]([H])(C(=O)OC([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[N+]1([H])[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(C([H])=N1)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C(F)=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])F)C([H])=C1[H]
[H]N([H])[C@]([H])(C1=C(N2C([H])([H])C([H])([H])N(C(=O)[C@]3([H])C([H])([H])N(C(=O)C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@@]3([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C(F)=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=NN([H])N=N1
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])O2
[H]N(C(=O)C([H])([H])OC1=C2C(N([H])C([H])=C2S(=O)(=O)C2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=NN=C(N1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]O[C@]1([H])[C@]2([H])C([H])([H])[C@]2([H])[C@@]([H])(N2C([H])=NC3=C(N=C(Cl)N=C23)N([H])C([H])([H])C2=C([H])C(I)=C([H])C([H])=C2[H])[C@]1([H])O[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N3C(=O)C([H])([H])C4(C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]N1C(=C(C2=C([H])C(Cl)=C([H])C(Cl)=C12)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=NC(N([H])C2=C([H])C([H])=C3N([H])N=C(C3=C2[H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])=C([H])C([H])=N1
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C2=C(C([H])=C1OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N2N(C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@](N([H])[H])(C2=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H])C(F)(F)F
[H]N([H])C(=S)N([H])\N=C(\C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C(F)=C1[H])/C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C(SC([H])([H])C([H])([H])N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(F)=C1[H])C1=C([H])C([H])=C([H])C(N([H])C2=C([H])C([H])=C3C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4C3=O)=C2[H])=C1[H]
[H]N(C(=O)[C@]1([H])C(=O)N2C3=C(C([H])=C([H])C([H])=C13)C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])C2=NC(=C([H])C([H])=N2)C2=C([H])N=C(N2C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])S1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[P@](=O)(O[H])[C@]([H])(N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[N+]([O-])=O)C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N2C([H])=C([H])N=C2C(=N1)N([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N1C2=C([H])C(=NN2C2=C([H])C([H])=C([H])C([H])=C2C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C(O[H])=C([H])C(=N2)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=C([H])C2=NC([H])=NC(N([H])C3=C([H])C([H])=C([H])C(Br)=C3[H])=C2C([H])=C1[N+]([O-])=O
CCOC1=CC(=CC=C1Cl)N1CCN(CC1)C(=O)CN1N=C(C(Cl)=C1C)C(F)(F)F
[H]N([H])C(=NC(=O)C1=C([H])C([H])=C(O1)C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]C1=NC(=NC([H])=C1Br)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[C@@]12C(=O)C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N=C(S1)N1N=C(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C(\C([H])=C(/[H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(O[H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C(C#C[C@]([H])(OC([H])([H])[H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])[H])C(=N1)C([H])([H])[H]
[H]N(C1=C2C([H])=C([H])C(OC([H])([H])[H])=NC2=NC([H])=N1)C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)[C@@]1([H])[C@]2([H])C([H])([H])N(C3=C(C([H])=C([H])C([H])=N3)[N+]([O-])=O)C([H])([H])[C@]12[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])N(C2=O)C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1N=C([H])C2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C([H])N=C12)C(=O)C1=C(F)C([H])=C([H])C([H])=C1F
[H]N(C(=O)C1=C([H])C([H])=C(S1)C1=NC(=NC([H])=C1[H])N([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C([H])SC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
CCCCCCCCN1C=C(CNC(C)=O)C2=CC(=CC=C12)C1=CC(C)=CC=C1
[H]N([H])C(=O)C1=C2N([H])C3=C(C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])C([H])([H])N2N=C1C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1C([H])=C(N=C1C1=NC([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C2OC([H])([H])OC2=C([H])C2=C1C1=C3C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(N=C1[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2F)C2=C([H])C([H])=C([H])C(OC(F)(F)F)=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])C([H])([H])N(C(=O)OC([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]S\C(=N/C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=N1
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C([H])C([H])=C3[H])C(=C2[H])C2=C([H])C(=C(C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])[C@]2(O[C@]1(C([H])([H])[H])[C@@]1([H])C(=O)N(C(=O)[C@@]21[H])C1=C([H])C(I)=C(C#N)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C1=C([H])C(SC([H])([H])C([H])([H])C([H])([H])[H])=NC([H])=N1)C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=NC([H])=C2Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C2=C(C([H])=C([H])C(Br)=C2[H])N(C([H])([H])C2=C([H])N([H])C([H])=N2)C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])[C@]([H])(C([H])([H])O[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])=NC1=C2C2=C(S1)C(=O)N(C([H])=N2)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(N([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(O1)C([H])([H])[H])C1=NC([H])=C([H])S1
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@]([H])(C([H])([H])C([H])([H])N2C(=C([H])C([H])=C2C(F)(F)F)C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
FC1=C(C=C(CC2=NNC(=O)C3=C2C=CC=C3)C=C1)C(=O)N1CCCC1C(=O)N1CCC2=C3C1CNC(=O)C3=CC=C2
[H]N1C(=O)C([H])=C([H])C2=C1C([H])([H])[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@]22N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3=NC([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(C(=O)C1=C([H])C2=C([H])C(F)=C([H])C([H])=C2N1C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C#N)C1=C([H])C([H])=C(I)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C3=C(O[H])N=C(N=C3N=C2[H])N([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])S(=O)(=O)O[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)[C@]1(C([H])([H])C([H])([H])N2C([H])([H])C([H])(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C2([H])[H])C([H])([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2C2=C1C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N3C(=O)C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])[C@]1([H])[C@@]2([H])C([H])([H])[H])C(F)(F)F
[H]N1C2=C(N=C1[C@@]1([H])N(C(=O)C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])(C4=NOC([H])=N4)C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])=C(Cl)C(Cl)=C2[H]
[H]N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C2C(=C([H])C(Cl)=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(OC1=NC(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=N1)C(OC([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]1(C([H])([H])C([H])([H])[C@@]([H])(N([H])[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]ON(C(=O)OC([H])([H])[H])[C@]([H])(C#CC1=NN(C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C(Br)=C(O[C@]3([H])C([H])([H])N([H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])S[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])O[H]
[H]C1=C2C([H])([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])C(=O)[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C(C1=O)(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])C2=C1C(=NC([H])=N2)N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N(N([H])C(=O)C([H])([H])SC1=NN=C(N1N([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C([H])([H])Cl)C(=O)C([H])([H])Cl
[H]N(C(=O)N([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2(C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])N1C2=NC3=C(N2C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C(=NC([H])=N1)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[H])[C@]([H])(C1=C([H])C(Br)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C(=O)[C@]2(N3C([H])([H])SC([H])([H])[C@@]3([H])[C@@]([H])(C3=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])[C@@]22C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C2([H])[H])C2=C1C([H])=C([H])C(Cl)=C2[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])S[H]
[H]N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])OC([H])=C2[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C1=C(N=C(S1)C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]1([H])[C@@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C([H])=C(Cl)C(=C2[H])C([H])([H])C2=NC([H])=C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S2)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)C1=C(Cl)C(=C2C(=C1Cl)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N1C([H])=NC2=C1N([H])C([H])=NC([H])([H])[C@@]2([H])O[H]
[H]C1=C([H])C2=C(C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]21[H]
[H]N1C(=O)N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C(N=C(O2)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(OC([H])([H])C([H])([H])[C@@]2(OC3=C(C(=C(O[H])C(=C3C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N([H])C1=C(Cl)C2=C(C([H])=NC([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1(C([H])([H])C(=O)N([H])C([H])([H])C2=C(Cl)C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C(=O)OC([H])([H])[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C3=C([H])C([H])=C([H])C([H])=C3N(C1=O)C([H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(N([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=NN(C([H])=C2C(=NC2=C1C([H])=C(Cl)C(Cl)=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([S-])=S
[H]OC1(C2=C(F)C([H])=C([H])C([H])=C2F)[C@@]([H])(C([H])([H])[H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C1=C([H])C(I)=C(N([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C(=C1[H])C(=O)N1C2=C(C([H])=C(C([H])=C2[H])N2C([H])=C([H])N=C2C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C2ON=C(N([H])[H])C2=C1[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C(=C1C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC([H])([H])C1=NC2=C(C(SC([H])([H])[H])=NN2C(=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(OC4([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C(Br)C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])[C@]1([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H][C@@]12C[C@]3([H])C[C@@H](CC[C@@]3([H])[C@H](\C=C\C3=CC=C(C=N3)C3=CN=CN=C3)[C@]1([H])[C@@H](C)OC2=O)NC(=O)OCC
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C2OC(=C(C2=N1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C3=C2N([H])C2=C3C3=C(C(=O)N([H])C3=O)C3=C2C([H])=C([H])C2=C3N(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C(F)C(F)=C(F)C(F)=C1F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(\C(=C1/C(=O)N([H])C2=C([H])C(=C([H])C([H])=C12)C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=NSC(N([H])C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])=C1\C(=N\C([H])(C([H])([H])[H])C([H])([H])[H])N([H])[H]
[H]O[C@]([H])(C1=C([H])C(N([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2OS(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1S2(=O)=O
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1(C([H])([H])S[C@@]([H])(C2=C([H])C(\C([H])=C(/[H])C3=NC4=C([H])C(Cl)=C([H])C([H])=C4C([H])=C3[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])N1C(=O)N([H])C2=NC3=C([H])C(N([H])C(=O)C([H])([H])[H])=C([H])C([H])=C3N=C2C1=O
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])[H]
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[H]\C(=C(\[H])C1=C([H])C([H])=C([H])S1)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]C1=C(N=C(S1)C([H])([H])[H])C#CC1=C([H])N=C([H])C(=C1[H])C1=NC([H])=C([H])C([H])=C1[H]
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[H]C1=C([H])C([H])=C(C(=N1)C1=C([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
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[H]OP(=O)(O[H])C([H])(N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])P(=O)(O[H])O[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)C([H])([H])[N+]1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N([H])C1=O
[H]N([H])C(=O)C(\[H])=C1\C2=C(C([H])=C([H])C([H])=C2[H])N(C(=O)C2=C(Cl)C([H])=C(C([H])=C2[H])N2N=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1(F)F
[H]N1N=C(C2=C1C(=C1N([H])N=C(C1=C2[H])C([H])([H])[H])[N+]([O-])=O)C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C2=C(OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])O[C@@]3([H])OC([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=NC([H])=C2S1
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[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N([H])C1=C([H])C([H])=C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C1[H])C2([H])[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1N=C(N(\N=C(/[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C1=S)C1=C([H])C([H])=C([H])C([H])=N1
FC1=CC=C(C=C1)C1=CSC(NN=C2CCCC2)=N1
[H]N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C([H])C([H])=C3[H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N1C([H])=C(N=C1[C@@]1([H])N([H])[C@]([H])(C2=C(C3=C([H])C([H])=C([H])C([H])=C3N2[H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])C1=C([H])C([H])=C(C([H])=C1I)C([H])([H])C([H])([H])OC(=O)[C@]1([H])[C@]2([H])N(C([H])([H])[H])C([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H][C@@]12C[C@H](NC3=NC=NC4=C3N=CN4[C@@H]3O[C@H](C[Se]C)[C@@H](O)[C@H]3O)[C@]([H])(C1)C1SC21
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C2=C([H])C([H])=C([H])C([H])=C2N(C([H])([H])[C@@]2([H])OC([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H])S1(=O)=O
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[H]N([H])C1=NC(N([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(=N1)N1C([H])([H])C([H])(N([H])C([H])([H])[H])C1([H])[H]
[H]OC1=C(C([H])=C(\C([H])=C2/N(C(=O)N([H])C2=O)C([H])([H])[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C(C#CC2=C([H])C(C(=O)N([H])[H])=C(S2)N([H])C(=O)N([H])[H])=C([H])S1
[H]N1N=C(C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C1=C(N([H])C(\C([H])=C2/C(=O)N([H])C3=C([H])C(N([H])C(=O)N([H])C4=C([H])C([H])=C(Cl)C([H])=C4[H])=C([H])C([H])=C23)=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])[C@]([H])(N([H])C(=O)C4=C([H])C([H])=NN=C4[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N([H])C1=NC2=C(C([H])=N1)C([H])=C(OC1=C([H])C([H])=C(F)C([H])=C1F)C(=O)N2C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(C2=C(OC1=O)C([H])=C(OC([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])=C2[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1(C([H])([H])S[C@@]([H])(C2=C([H])C(\C([H])=C(/[H])C3=NC4=C(C([H])=C3[H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C4([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C2=C(C3=C([H])C([H])=C(C([H])=C3O2)S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
CCCCOC1=NO[N](O)=C1S(=O)(=O)C1=CC=CC=C1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(=NN1[H])C1=C([H])C(N([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(N(N2C([H])([H])C([H])([H])C(O[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C([H])([H])[C@]2([H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)N([H])C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\[H])C3=C([H])C(=C([H])N3[H])C3=C([H])C(=C([H])C([H])=C3[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2=C1[H]
[H]N(C(=O)[C@@]([H])(N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C(=O)C([H])([H])N(C(=O)[C@@]([H])(N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=N1)C1=NC([H])=C([H])N1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])N(C([H])([H])SC1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)C1=C([H])SC2=C1C([H])=C(Cl)C([H])=C2[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(OC([H])([H])C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=NN(C2=NC([H])=NC(N3C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)C(CCCCNC(C)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CS)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O
[H]N(C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])N([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])SC(=N1)C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C#N
[H]N(\C(=N/C#N)N([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(Cl)(Cl)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1OC([H])([H])[H]
[H]N(C(=O)C1(SC([H])([H])C([H])([H])S1)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]O[C@@]([H])(C([H])([H])S[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C(=C(/[H])C1=C(C#N)C([H])=C([H])C(OC([H])([H])C2=C([H])SC([H])=C2[H])=C1[H])\C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C2C([H])=C(C(=NC2=C1OC([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(N([H])C([H])=N1)C([H])([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])[C@]2([H])[C@]3([H])C([H])([H])C([H])([H])[C@]4([H])N([H])C(=O)C([H])=C([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C2=C(C([H])=C1[H])C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(S1)C1=NN(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C1=C([H])N2C(=NC(=C2C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N2C(=O)[C@](N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]3([H])N(C(=O)[C@@]4([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[C@]([H])(O[H])C3([H])[H])C([H])([H])C3=C([H])C([H])=C([H])S3)C([H])([H])O[H])(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])[C@@]2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]N1C(=O)C2=C(OC(=O)C([H])=C2C([H])([H])C([H])([H])[H])N=C1C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C2=C(O[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])N([H])C(=O)OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2S1
[H]C1=C([H])C([H])=C2C(=O)N(C3=C([H])C([H])=C(OC4([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C4([H])[H])C([H])=C3[H])C(=NC2=C1[H])C([H])([H])[H]
[H]N([C@]1([H])C(=O)N(C2=C(F)C([H])=C(C([H])=C2[H])N2C([H])=C([H])N=C2C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C(Cl)C([H])=C([H])C2=C1[H]
[H]OC1=NC2=C([H])C3=C([H])C(=C([H])C([H])=C3N([H])C2=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)N([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C([H])C(=N1)C([H])([H])SC([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)O[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C#CC([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1N=C(N=C1C1=NC([H])=C([H])N=C1[H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C1\C(=C1/N([H])\C(\C([H])=C1[H])=C(/C1=N/C(/C([H])=C1[H])=C(\C1=N\C(\C([H])=C1[H])=C2\C1=C(F)C([H])=C(F)C([H])=C1[H])C1=C(F)C([H])=C(F)C([H])=C1[H])C1=C(F)C([H])=C(F)C([H])=C1[H])C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]N([H])C([H])([H])C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C(=O)N1C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(O1)C([H])=C([H])C(OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])=C2[H])[C@]([H])(C(=O)N([H])[C@@]1([H])C(=O)C([H])([H])N(C(=O)C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C2=NC(=C3C([H])=C(N([H])C(=O)C(\[H])=C(/[H])C4=C([H])C([H])=C(Cl)C([H])=C4[H])C([H])=C([H])C3=N2)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(O[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C2=C13
[H]N(C(=O)[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
CCOC1=CC=C(C=C1)C(C1=NC2=CC=CC=C2N1)=C1C(=O)NC2=C1C=CC=C2
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
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[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C(=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C1=NC([H])=C(N1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C(=O)N([H])C(=O)C(N2C([H])([H])C([H])([H])N(C(=O)C3([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])(C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(OC([H])([H])[H])C(=O)N(C([H])([H])C1=C([H])SC([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C(Cl)N=C(Cl)C([H])=C1C([H])([H])[H]
[H]C1=C(C([H])=C2N1C([H])([H])C([H])([H])N(C2=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]O[C@]1([H])[C@]([H])(O[H])[C@]2(C(=O)N([H])C([H])([H])[H])C([H])([H])[C@]2([H])[C@@]1([H])N1C([H])=NC2=C1N=C(N=C2N([H])C([H])([H])[H])C#CC1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C(=NN([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])=C1[H])N([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])OC([H])([H])C([H])([H])C(=O)N([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])[H]
[H]O[C@@]1([H])\C([H])=C([H])/C(=O)[C@]23C(=O)N([H])[C@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]2([H])[C@]([H])(C(=C([H])[C@@]3([H])\C([H])=C(C([H])([H])[H])\C([H])([H])C([H])([H])[C@]1([H])O[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C(C([H])=C1[H])C1=C([H])C([H])=C(F)N=C1[H])C1=C(OC([H])([H])[H])C(C#N)=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1N=C(C2=C(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C3=C([H])C(OC([H])([H])[H])=C([H])C(=C3N=C12)C([H])([H])[H])C([H])([H])[H]
[H]N1N=NC(=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])OC1=C([H])C([H])=C(\C([H])=C(/[H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])C([H])=C(C#CC3=C([H])C([H])=C([H])N=C3[H])C([H])=C12
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])N=C1N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C2=C(S1)N1C(=NC([H])=C1C([H])([H])[H])C(=N2)N([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)C4=C([H])C([H])=C([H])C([H])=C4[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])SC(=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N1C(=NC2=C1C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C21)C1=C([H])C([H])=NC([H])=C1[H]
[H]OC1=C(C([H])=C(\C([H])=C(/[H])C2=C([H])C([H])=C([H])S2)C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(OC([H])([H])C(=O)O[H])C(Br)=C(S1)C1=C([H])C(N([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])C2=C(C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(N1C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OP(=O)(O[H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C(=O)N([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C(N=C2N1C(=O)C(C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])=C(N2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])C([H])([H])C([H])([H])N2[H])=C([H])C([H])=C1[H])C1=C([H])C(Br)=C([H])C(Br)=C1O[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C2C(O[H])=C([H])C([H])=C([H])C2=C1[H]
[H]C1=C(N=NN1C1=C([H])C(=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]N(\N=N\C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C2=C(N=C([H])N=C2N([H])C2=C([H])C(Br)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]ON1C([H])=C(Br)C([H])=C(N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])C1=O
[H]N(C(=O)C1=C([H])C(=NN1C1=C([H])C([H])=C2C([H])=C(Cl)C([H])=C([H])C2=C1[H])C([H])([H])[H])C1=C(F)C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C([H])C(OC([H])([H])C(=O)OC([H])([H])[H])=C(C([H])=C1Cl)C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=NC([H])=NC2=C([H])C([H])=C(\N=N\N(C(=O)OC3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)C([H])([H])[H])C([H])=C12
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(C2=NN3C([H])=C([H])N=C3C(=N2)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1C([H])([H])[H]
[H]C(=O)[C@]1([H])N(C(=O)[C@@]2([H])N(C(=O)OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(N([H])C(=O)C3=NC(C#N)=C([H])N3[H])C(=C2[H])C2=C([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C(N([H])C3=C2C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(\[H])=C2/C(=O)N([H])C3=C([H])C([H])=C(C([H])=C23)S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])N=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])SC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C([H])C(C#N)=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2N(C(=C3[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
COC[C@H](C)OC1=CC(CCC2=C(F)C=CC=C2F)=CC(=C1)C(=O)NC1=NN(C)C=C1
[H]OC1=C([H])C([H])=C([H])N(C1=O)C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C(=C(C#N)C#N)C1=C([H])C([H])=C([H])N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
C(N1C2=C(CCCC2)C2=C1C=CC=C2)C1=CC=C(CN2C3=C(CCCC3)C3=C2C=CC=C3)C=C1
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C([H])=C2N=C([H])C([H])=C(N([H])C3([H])C([H])([H])C3([H])[H])C2=C1[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N([H])C2=C([H])C(N([H])C3=NC(=C([H])C([H])=N3)C3=C([H])N=C([H])C([H])=C3[H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N2N=NN=C12)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])SC1=NN=C(N1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1O2
CCOC1=CC=C(C=C1)S(=O)(=O)N(CC(=O)N\N=C1/C(=O)NC2=CC=CC=C12)C1=CC=C(C)C=C1
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[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)C(=O)C([H])=C2OC([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C(=O)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
[H]OC(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@]1([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
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[H]N([H])[C@]([H])(C(=O)N1C([H])([H])SC([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C(C#N)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C(Br)S1
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])SC(=C2[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
COC1=CC=CC=C1CC(CN1CCC2(CC1)OCCC1=C2SC=C1)C(=O)N(C)C
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[H]O[C@@](C([H])([H])C1=C([H])C([H])=C(C([H])=O)C([H])=C1Cl)(C([H])([H])C(C1=C([H])C(F)=C([H])C([H])=C1OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]N(C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=NC([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N([H])C(=O)C1=C(N([H])[H])C2=C(S1)N=C(C([H])=C2C([H])([H])OC1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C2N(C(=C(C2=C1[H])C([H])([H])[H])C([H])([H])N1C([H])=NC([H])=C1[H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
COC1=CC=C(C=C1)C1=C(COC2=CC=C(CCC(O)=O)C=C2)C=CC=C1
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)O[H]
[H]OC(=O)C([H])([H])[C@]1(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)O[C@@]2([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C2=C1C([H])([H])C([H])([H])O2
[H]C1=C(N=C(O1)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
OC1(CC2=CC=CC=C2)CCN(C1)C1=CC(Cl)=C(C=C1)C#N
C1CCC(CC1)NC1=CC(=CC=N1)N1C2=C(C=CC=C2)N=C1C1=CC2=CC=CC=C2C=C1
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=C(N([H])C(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(O2)C2=C([H])N=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C1=C(C([H])=NC(=N1)N(C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C(\[H])=C(/[H])C2=C([H])N=C([H])C(C#N)=C2N([H])C2=C(C3=C(N([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C([H])C(=C1[H])C(=O)OC([H])([H])[H]
[H]N1C(SC([H])([H])C([H])([H])[H])=NC(=C1C1=C([H])C([H])=NC(Cl)=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C1=C(N([H])C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C2=NN(C([H])=C2[H])C2=C([H])C([H])=C(O[H])C([H])=N2)C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NN2C(=NC(=C2C([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC(=C(S1)C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C2C(=O)C3=C(N([H])N=C3C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=NC1=NC(=C([H])S1)C([H])([H])SC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])C1=N[C@]([H])(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H])N([H])[H]
[H]OC([H])([H])C([H])([H])N(C(=O)C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C([H])=C2N1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)N(C(=O)C([H])([H])[C@@]12[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(OC([H])([H])C([H])([H])C2=C([H])N([H])C4=C2C([H])=C([H])C(Cl)=C4[H])N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C2C([H])=C([H])C(N([H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])=C([H])C2=NN1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
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[H]N1C(=O)C2=C(N=C1C([H])([H])[H])C([H])=C([H])C([H])=C2Cl
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[H]C(=O)C1=C([H])N(N=N1)C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C1([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C(=NC2=C1C([H])=C(OC([H])([H])C([H])([H])F)C([H])=C2[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C2N(C(=O)OC(C2=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])C(=C([H])C([H])([H])C1([H])[H])C(=O)N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
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[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(N2C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2SC([H])([H])C1([H])[H]
[H]N1C([H])=C([H])N=C1C(=O)N1C([H])([H])C([H])([H])C([H])(OC2=NC([H])=C([H])C([H])=C2C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(N=C2[H])N2C([H])([H])[C@]3([H])N([H])C([H])([H])[C@@]2([H])C3([H])[H])C([H])=C([H])C([H])=C1[H]
NC(=O)C1=CC=C2C3=C(CCOC2=C1)C=C(S3)C1=NNC(=O)N1C1=CC=CC=C1Cl
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[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N(C2=NC3=C([H])C([H])=C([H])C([H])=C3C(=C2C1=O)C([H])([H])[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])SC1(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC#C[H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])[H])=C1OC([H])([H])[H]
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[H]OC1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]O[C@]1([H])C([H])([H])[C@@]23C(=C([H])C(=O)C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])[C@@]1([H])[C@]2([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@]31[H]
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CN1C(\C=C\C2=CC=C3OCOC3=C2)=CC2=C1C(=O)N(C)C(=O)N2C
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[H]O[C@]([H])(C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C2=C3N(C([H])=C2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])S(=O)(=O)N(C3=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]C1=C([H])C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])N([C@]([H])(C4=C([H])C([H])=C(C([H])=C4[H])S(=O)(=O)C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C3([H])[H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])C21C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[C@]12C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[C@]1([H])N1C(=O)C([H])([H])[C@@]([H])(OC(=O)C([H])([H])[H])C1=O)C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(C([H])=C([H])C([H])=C3OC([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[H])C1=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(=C(C([H])=C1[H])N1C(=O)C2=C(OC([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3C(OC([H])([H])C([H])([H])[H])=C2C1([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]OC1=NC([H])=C(C(O[H])=N1)C1=C([H])C2=C(C([H])=C1[H])C(=C([H])N2C(=O)N(C([H])([H])[H])C([H])([H])[H])C(=O)C1=C2N(C([H])=C1[H])[C@]([H])(SC2([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C([H])C(Cl)=C2[H])[C@@]1([H])C(=O)N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N1C(=O)N([H])[C@]2(N(C(=O)N([H])C3=C([H])C([H])=C(C([H])=C23)[N+]([O-])=O)C([H])([H])[H])C1=O
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[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(C3=C(O2)C([H])=C([H])C(=C3O[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C1(N([H])C([H])([H])C(=O)N2[C@]([H])(C#N)C([H])([H])C([H])([H])[C@]2([H])C#N)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C(F)=C([H])C([H])=C2[C@@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(\C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])[H])=C1\C([H])([H])[C@@]2([H])N(C([H])([H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
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[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])S1)(C(F)(F)F)C(F)(F)F
[H]N(C(=O)C([H])([H])N1C(Cl)=C([H])N=C(N([H])C([H])([H])C(F)(F)C2=[N+]([O-])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]1([H])C([H])([H])N([H])[C@]([H])(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(Cl)C(=C([H])C(Cl)=C1S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])C(=O)C1=C([H])C2=C3N(C([H])=C2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])S(=O)(=O)N(C3=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C(N=[N+]=[N-])C(I)=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N=C(C1=C([H])C([H])=C([H])S1)C([H])([H])C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(\N=C(/[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NN=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C2C(=C1[H])[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])C([H])([H])O[C@]2([H])C([H])([H])C([H])([H])[C@@]([H])(C(\[H])=C(/C([H])([H])[H])[C@@]3([H])OC(=O)[C@@]4([H])N(C(=O)C(=O)[C@]5(O[H])O[C@@]([H])([C@@]([H])(OC([H])([H])[H])C([H])([H])[C@@]5([H])C([H])([H])[H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])\C(=C([H])\[C@]([H])(C(=O)C([H])([H])[C@]([H])(O[H])[C@@]3([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[C@@]2([H])OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C2C(OC(=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])=NC([H])=N1)C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=C([H])C2=C(N=C1[H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C1=NC2=C(N1[H])C([H])=C([H])C(F)=C2[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])N=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N(C(=O)OC2=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(S1)S(=O)(=O)\N=C1/C(=O)C2=C([H])C([H])=C([H])C([H])=C2C([O-])=C1[N+]1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C2C(O[C@]([H])(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])[C@@]([H])(C2=O)C([H])([H])[H])=C1[H]
[H]N(N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(=C1OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)C1=C([H])[C@@]3([H])C(=O)[C@@]4(OC(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(C3([H])[H])[C@]14O2)C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C(C(=O)OC([H])([H])C([H])([H])[H])C(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C1=C2N([H])C([H])=NC2=NC(Cl)=N1)C([H])([H])C([H])([H])N1C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(O1)C([H])([H])[H])N1N=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C#N)C(=O)N([H])[C@]([H])(C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC1=NC(=C([H])C(=N1)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C2=C(N=C(N=C2C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N([H])C(=O)C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3OC([H])([H])C([H])([H])OC3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]OC([H])([H])[C@@]1([H])N([H])[C@@]([H])(C2=C([H])N([H])C3=C2N=C([H])N([H])C3=O)[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC([H])([H])C([H])([H])N([H])C1=NN=C(O1)C1=C([H])N2N=C([H])N=C(N([H])C3=C(F)C([H])=C(F)C(=C3[H])C(=O)N([H])C3([H])C([H])([H])C3([H])[H])C2=C1C([H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])[C@]1(OC(=O)C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])[H]
[H]OC1=C(O[H])C(Br)=C([H])C(\C([H])=C(/[H])C(=S)N([H])C([H])([H])C2=C([H])C(O[H])=C(O[H])C(O[H])=C2Br)=C1[H]
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[H]OC1=C(C([H])=C2C(N([H])N=C2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=C(C([H])=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C(C([H])=C([H])C(=C1[H])C(=O)N([H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(N([H])[H])C(=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])S(=O)(=O)N([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C(C([H])=C(C([H])=C12)C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC(Cl)=C([H])N(C1=O)[C@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])C1=C(C([H])=C(OC([H])([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C#CC([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])C2=C1[H]
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[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(N([H])C2=C([H])C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C3=O)=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC(=O)C([H])([H])C2=C([H])C([H])=C(N([H])C3=C([H])C([H])=NC(=C3[H])C(F)(F)F)C([H])=C2[H])C([H])=C1[H]
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[H]N1C(=O)N([H])[C@]2(C1=O)C1=C([H])C(F)=C([H])C([H])=C1OC([H])([H])C2([H])[H]
[H]N(\N=C1/C([H])=C([H])C(=O)C2=C1C([H])=C([H])C([H])=N2)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]N([H])C1=N[C@@]([H])(N2C(=NC3=C2C([H])=C([H])C([H])=C3[H])N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N1C3=C(N=C1C([H])([H])[H])C([H])=C([H])C([H])=C3[H])C2([H])[H]
[H]OC1=C(C([H])=C([H])C(F)=C1[H])C1=C(C(=NC(=C1[C@@]([H])(O[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1N=C(C([H])=C1C1=C([H])C([H])=C2C([H])=C(OC([H])([H])[H])C([H])=C([H])C2=C1[H])C(F)(F)F)C([H])([H])[H]
[H]\C(=C(\[H])C1=C(C(OC([H])([H])C([H])([H])[H])=C(OC(=O)C([H])([H])[H])C([H])=C1[H])[N+]([O-])=O)C1=NC2=C(C([H])=C([H])C([H])=C2OC(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]1([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])OC(=O)C1=C([H])C(O[H])=C(C(=O)C2=C(O[H])C([H])=C([H])C3=C2C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(O[H])=C1[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(=C2[H])C2=C(C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C(OC3=C(C#N)C(=C([H])C([H])=C23)C(F)(F)F)C(OS(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F)=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C(=O)[C@]([H])(OC2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])[C@]([H])(C([H])([H])[H])C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])N([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C(=O)N(C1=C(Cl)C(=C(Cl)C([H])=C1[H])C([H])([H])OC1=C2N=C(SC2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(Cl)N(C2=NC(=C(N12)C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(F)(F)F)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2OC([H])=C(C2=C2O[C@@]3(N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C2=C1[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC(=O)[C@@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])S1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])N1C(=NC(=C1C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(F)(F)F
[H]OC(=O)C1=C([H])C(N([H])C2=NC(=NC3=C(C#N)C([H])=NN23)N([H])C2=C([H])C(N([H])C(=O)C([H])([H])[H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC1=C2C([H])=C(N([H])C(=O)\C(=C([H])\C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])[H])[C@@]([H])(OC(=O)N([H])[H])\C(=C([H])\[C@]([H])(C([H])([H])[H])[C@@]([H])(O[H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(SN=C2N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C3=C4N(C(=O)C([H])([H])C5=C([H])C(OC([H])([H])[H])=C([H])C([H])=C5[H])C([H])([H])C([H])([H])[C@@]([H])(C4=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H]
[H]C1=C2C(=C(S1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[C@]([H])(OC([H])([H])[H])O[C@]21C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]SC([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C(C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]OC1=C(OC([H])([H])[H])C(=C2N=C(SC2=C1C([H])([H])C([H])([H])[H])N([H])C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(C#CC2=C([H])N=C3C([H])=C([H])C([H])=C([H])N23)=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])N1C([H])=NC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]C#CC([H])([H])N(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[C@]1([H])C([H])([H])C2=C(N=C(N=C2C([H])([H])C1([H])[H])N([H])[H])N([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C(N=C(N1C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(N=C2C(=O)OC([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C3C(=NC([H])=C([H])C3=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C2=O
[H]N(C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])N(C([H])=N1)C([H])([H])C([H])([H])[H]
ClC1=CC=C(C=C1)C1=NC(=C(N1CCCCCCCNC1=C2CCCCC2=NC2=CC=CC=C12)C1=CC=CC=C1)C1=CC=CC=C1
[H]N(C(=O)C([H])([H])SC1=NN=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C(S1)C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
OC[C@H]1O[C@@H](CC(=O)\C=C\C2=CC=C(O)C=C2)[C@H](O)[C@@H](O)[C@H]1O
[H]C1=C2N(C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])N(C2=C([H])C(=C1[H])C(F)(F)F)[C@@]([H])(C1=NN(N=N1)C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]C1=C([H])N=C(O1)C(=O)[C@@]1([H])C([H])([H])C2=C(C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C2C(=O)N([H])C(=O)C(=O)C2=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C2C([H])=C([H])C(=NC2=C1OC([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)C1=NOC2=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)N([H])[C@@]2([H])C([H])([H])C3([H])N(C([H])([H])C4=C([H])C([H])=C([H])O4)[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=NOC(=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C#CC([H])([H])[H])C1=C([H])C([H])=C(OC2=NC([H])=C(Br)C([H])=N2)C([H])=C1[H]
[H]C1=C(C([H])=C(Br)C(=C1[H])N1C(=O)N(C2=C1N=C(N=C2N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC1=C(C([H])=C(C([H])=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
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[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C([H])C(=C([H])C([H])=C2N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])N(O[C@@]2([H])C([H])([H])C([H])([H])C(=O)[C@@]12[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C(C2=C([H])N(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[H])=C(C1=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C(=O)[C@@]([H])(N([H])C(=O)C2=C([H])C3=C(N2[H])C([H])=C([H])C(Cl)=C3[H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C(=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C([H])([H])[H])C([H])([H])N2C1=C(Cl)C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C2C(=C1\C([H])=C1/C(=O)N([H])C3=C([H])C([H])=C(Cl)C([H])=C13)C([H])([H])C([H])([H])OC2=O
[H]N([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1C1=C([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2O1
[H]OC(=O)C1=C(C(=NC2=C([H])C([H])=C(F)C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N(C(=O)C2(C1=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])[C@@]1([H])N(C2=NC3=C(N([H])C([H])([H])N3C([H])(C([H])([H])[H])C([H])([H])[H])C(=N2)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C(=O)N(C([H])([H])C(=O)N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C(C#N)=C2[H])C([H])([H])C1([H])[H]
[H]C([H])=C(C([H])([H])[H])C([H])([H])N([H])C1=C([H])C([H])=NC2=C1C1=C(S2)C(=O)N(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=NC([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N1C(C#N)=C([H])C2=C1C(=NC([H])=N2)N([H])C1=C([H])C(Cl)=C(OC2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=N1
[H]N(C(=O)C([H])([H])OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)C1=C([H])C(=C(Cl)C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C1=C(C([H])([H])[H])C([H])([H])C([H])([H])N(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2OC([H])([H])[H])C([H])([H])[H])C1=O
[H]N1C(=O)C([H])=C(C2=C1C([H])=C([H])C1=C2OC([H])([H])[C@]([H])(N1C([H])([H])[H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=C([H])N3C([H])=C(C([H])=C([H])C3=N2)C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C([H])N=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])[H]
[H]OC1=C(C([H])=C(\C([H])=C2\C(=NC([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])N=C2[H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(I)C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(Cl)N=N3)C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
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[H]C1=C([H])C(=C([H])C([H])=C1C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[C@]([H])(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])[H]
[H]C1=C(OC([H])([H])[H])N=C2C(=C1[H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])[C@]2([H])N(C1=NN(N=N1)C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C([H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN([H])C2=C1C([H])=NC(OC1=C(F)C([H])=C(F)C([H])=C1[H])=N2
CN1CC[C@@H]([C@H](CCC[N+]23CCS[Re]22(=O)SCCN2C(=O)C3)C1)C1=CC=C(Cl)C=C1
[H]OC1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])[C@]([H])(C([H])([H])N([H])[H])C([H])([H])C([H])([H])C2([H])[H]
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[H]N=C(N([H])C1=C(\C([H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H])N([H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H]
[H]O[C@@]([H])(C1=C(C2=C([H])C([H])=C([H])C([H])=C2O1)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])C([H])([H])[H])N1N=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)C1=C(N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])[C@]([H])(C1=NOC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C3=C2C(=C([H])C(=C3[H])C(=O)C([H])([H])Br)C1=O
[H]N1N([H])C(N=NC1=C1C([H])=C([H])C(=O)C([H])=C1[H])=C1C([H])=C([H])C(=O)C([H])=C1[H]
[H]N([H])C([H])([H])C1=C([H])N=C2C(C([H])=C([H])C([H])=C2C(F)(F)F)=C1C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1N1C(=O)C(C1=O)(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)\C(N([H])C(=O)\C1=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C2N([H])C([H])=C(C2=NC(=N1)N([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])O[H]
CC1=CC2=C(N=CN=C2C=C1)N1CCN(CC1)C(=O)[C@H](N)CC1=CC=C(Cl)C=C1
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])[C@@]([H])(O[H])C([H])([H])N2[H])=C([H])C(O[H])=C1[H])C1=C([H])C(Br)=C([H])C(Cl)=C1O[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C(=C1C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C(C([H])=O)C(=NC(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C2=C(C([H])=C(S2)C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C3=C([H])C([H])=C(Cl)C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC(=N1)N([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(=C1[H])[C@@]1([H])SC(=NN1C(=O)C1=C([H])C(F)=C([H])C([H])=C1[H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N([H])C1=NN2C(=N1)N(C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C(=C([N+]#[C-])C2([H])C1=C(C([H])=C(C#N)C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2C(=O)C([H])=C(OC2=C1[H])C1=C([H])C([H])=C(O[H])C(O[H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(N([H])C([H])=C1C([H])([H])[H])C(\[H])=C1/C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12
CCOC1=CC=C(C=C1)N1C(=O)C2=CC=CN=C2N=C1[C@@H](C)N(CC1=C[N](O)=CC=C1)C(=O)CC1=CC=C(OC(F)(F)F)C=C1
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[H]O[C@@]12N(C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])[C@]3([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC(=O)[C@@]1(F)[C@]2([H])C([H])([H])[C@@]([H])(OC([H])([H])C3=C([H])C(F)=C([H])C(F)=C3[H])[C@@](N([H])[H])(C(=O)O[H])[C@]12[H]
CN1C=CC2=C1C(OC1=CC=C(NC(=O)NC3=CC=CC=N3)C(Cl)=C1)=NC=N2
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]([H])(C1=C(F)C([H])=C([H])C(F)=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
CCSC1=NC(=C(N1)C1=CC=C(C=C1)S(C)(=O)=O)C1=CC=C(Cl)C=C1
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C2=C([H])C([H])=C([H])C([H])=C2N([H])C1=O)S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])N1[H]
[H]O[C@@](C1=C([H])C([H])=C(C([H])=C1[H])N(C1([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)(C([H])([H])[H])C(F)(F)F
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[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(C([H])=C(C([H])=C1[H])C([H])([H])N(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=NC3=C(C(=NN13)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(Cl)C(OC([H])([H])[H])=C1[H])C2([H])[H]
[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=NC(=NS1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C2=C(N=C1[H])C1(C(=O)N2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N(C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C2=C(N([H])C(=N2)C([H])([H])C2=C([H])C([H])=C([H])C(F)=C2F)C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C(=N\OC([H])([H])C([H])([H])[H])\C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)C2=C([N+]([O-])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(N([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N(C2=C1C([H])=NC(=N2)C#N)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=N1
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[H]OC1=C([H])C2=C3[C@](O[H])(OC2=C([H])C1=O)C([H])([H])C([H])([H])[C@]1([H])[C@]3(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C1OC1=NC([H])=C(C([H])=C1Cl)C(F)(F)F)S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2F)N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])C(=S)N1N=C(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)OC1=C([H])C([H])=C2N(C([H])([H])[H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3(C2=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C([H])C(=C([H])C([H])=C2N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(OC([H])([H])[H])C([H])([H])[H])[C@]([H])(C2([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]C([H])([H])O[C@]1([H])OC([H])([H])[C@]2(O1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC(C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(P(=O)(O[H])O[H])P(=O)(O[H])O[H]
[H]N(C(=O)C([H])([H])C1=C(N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])[H])[C@]([H])(C1=NC2=C(N1[H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C([H])([H])[C@]2([H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC1=C(C(=O)N([H])C([H])([H])C([H])([H])[H])C(O[H])=C(C([H])=C1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]1([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]1([H])O[H]
[H]O[C@@]1([H])\C(=C(/[H])C2=C([H])C(F)=C([H])C(F)=C2[H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])[C@@]4([H])N(C(=O)C([H])=C([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])N(C1([H])[H])S(=O)(=O)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C#N)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1Cl)C(=O)OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC(=O)C3=C([H])C(Cl)=C(N([H])[H])C([H])=C3OC([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])N=C(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=S)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])C([H])([H])OC1=C([H])C(=O)N(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=C([H])C(N2C([H])([H])C([H])([H])N(C(=O)[C@]([H])(C([H])([H])C(=O)N3C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])[C@@]([H])(N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=NC(C2=NN=C(O2)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]O[C@@](C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(\N=C(/C1=C([H])C2=C(OC1=O)C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
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[H]N([H])C([H])([H])C1=C2C(O[C@@]([H])(C3=C2C([H])=C([H])C2=C3C(=C([H])C(N2[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])=C([H])[H])=C([H])C([H])=C1[H]
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[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC2=C1N([H])C([H])=NC([H])([H])[C@@]2([H])O[H])C([H])([H])[H]
CC(C)(C)C1CCCN1C[C@@H](O)CNS(=O)(=O)C1=C2C=CC=CC2=CC=C1
[H]C1=NC2=C(OC3([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])N=C([H])N=C2N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
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[H]S\C(=N\C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])N(N=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C(N=C12)C#CC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])N([H])OC([H])([H])[H]
[H]OC(=O)[C@]([H])(C([H])([H])C1=C([H])C(=C(OC([H])([H])C([H])([H])[H])C([H])=C1F)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NC([H])=C([H])S1
[H]N([H])C1=NC(=NC2=C1C(=C(N2[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])O1
[H]N1C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(F)C([H])=C1[H])[C@@]([H])(C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2Cl)=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=C(\[H])C1=C([H])C2=C(SC([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])\C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C(N(C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
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[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C([H])=NC([H])=C2[H])=N1
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[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])S(=O)(=O)C([H])([H])[H]
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[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])=O)C([H])([H])C([H])([H])N(C(=O)C(F)(F)F)C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(C2=NON=C12)[N+]([O-])=O
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C([H])=C(C1=O)C1=C([H])C([H])=C(C([H])=C1Cl)C(F)(F)F)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1C(F)(F)F
[H]N(C1=C([H])C([H])=C([H])N=C1[H])C1=C2C([H])=C([H])C(Cl)=C([H])C2=NC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12
[H]OC([H])([H])C([H])([H])N([H])C1=NC([H])=C2N=C([H])N=C(N([H])C3([H])C([H])([H])C4=C(C([H])=C([H])C([H])=C4[H])C3([H])[H])C2=C1[H]
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[H]O[C@]([H])(C([H])([H])S[H])C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C(=O)[C@@]([H])(N([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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COC1=NC(Cl)=NC(C)=C1NC1=NC(Cl)=CN([C@@H](COCCF)C2CC2)C1=O
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[H]OC(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C2O1
[H]OC(=O)C([H])([H])SC([H])([H])C([H])([H])C([H])([H])S[C@@]1([H])C(=O)C([H])([H])[C@@]([H])(O[H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC([H])([H])[H]
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[H]N1C(=NC2=C(Cl)C([H])=C([H])N=C12)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
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C[C@@H](NC(=O)C1=CNC2=NC=C(N=C12)C1CC1)C(=O)N1CCC1
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[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N2C(SC([H])([H])[C@@]2([H])C2=C([H])C([H])=C([H])C([H])=C2F)=C(C1=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1=N[C@@]2([H])N(C(=O)N(C(=O)[C@@]2([H])N1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@@]([H])(N([H])C(=O)[C@]1([H])SC([H])([H])C([H])([H])N1S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]C1=C(C([H])=C(N1C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N(C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])F)C([H])([H])C([H])([H])C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
NC1=NC2=C(S1)C=C1CCN(CCO)CCC1=C2
[H]ON([H])C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C([H])=C([H])[H])C([H])=C2C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(OC2=C([H])C3=C(SC(=N3)N([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])=C([H])C([H])=N1)C([H])([H])[H]
[H]C1=C([H])N2C(=NN=C2C2([H])C([H])([H])C([H])([H])C(F)(F)C([H])([H])C2([H])[H])C(OC2=C(C(Cl)=C([H])C([H])=C2[H])C([H])([H])[H])=C1[H]
[H]N(\N=C(/[H])C1=C([H])C2=C(OC([H])([H])O2)C(OC([H])([H])[H])=C1[H])C(=O)C1=C([H])N=C([H])C([H])=C1[H]
CCB(CC)OC(=O)[C@@H](N)CCCCNC(=S)NC1=CC=C(C=C1)S(N)(=O)=O
[H]C1=C([H])N(C([H])=N1)C([H])([H])[C@@]1([H])SC2=C(C([H])=C(F)C([H])=C2[H])[C@@]1([H])OC([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1F
[H]OC1=C(C([H])=C(\C([H])=C2/SC(=O)N([H])C2=O)C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C(=C([H])C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=O)\C(N1[H])=C1\C2=C(N([H])C([H])=C2[H])C(=O)N([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1(C([H])([H])S[C@@]([H])(C2=C([H])C(\C([H])=C(/[H])C3=NC4=C(C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(C([H])=C(SC2=C([H])C([H])=C(C([H])=C2[H])C(=N\OC([H])([H])[H])\C([H])([H])[H])S1)[C@]1(OC(OC1([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C(N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)[C@]1([H])N(C(=O)C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C1([H])[H]
[H]OC1(C([H])([H])C([H])([H])N2C(=O)N(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1F)C1=C([H])N=C([H])O1
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]1([H])C3=C(C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C1=NC(=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C2=C(C([H])=C1C([H])([H])[H])S(=O)(=O)N(C([H])([H])N2[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]12C([H])([H])C3=C(N=C([H])C(=C3[H])C3=C([H])C([H])=C(Br)C([H])=C3[H])[C@]3([H])OC4=C(OC([H])([H])[H])C([H])=C([H])C5=C4[C@]13C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C5([H])[H]
[H]C1=C(N(N(\C1=N\C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
CC1=CC(CCC2=CC(=CC(CCC3=NC(N)=CC(C)=C3)=C2)C#N)=NC(N)=C1
[H]N([H])C1=C([H])C(=NC2=C([H])C([H])=C(N([H])C(=O)C(\[H])=C(/[H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C2C([H])=C([H])C([H])=C([H])C2=C2C(=N1)C([H])([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C(=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)OC([H])([H])[H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2S1)N([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[C@@]([H])(C#N)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
COCCC1(CCCC1)C(=O)N[C@@H](CC1=CC=C(C=C1)C1=C(C)N(C)C(=O)N(C)C1=O)C(O)=O
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2(C([H])([H])N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C3=NOC(=N3)C3=C([H])OC([H])=C3[H])C(F)=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])(OC2=C(OC3=C([H])C([H])=C([H])C([H])=C3F)C([H])=C([H])C([H])=C2F)C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N([C@@]([H])(C([H])([H])OC(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])S1)C(=O)C([H])([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C(F)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C2=C1C([H])([H])N([H])C2=O
[H]O[C@]([H])(C(\[H])=C(/[H])C(=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN=NN1C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]N([H])C([H])([H])C1(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])N(N=C1[H])C([H])([H])C1=C([H])C(=C([H])C(N=[N+]=[N-])=C1[H])C([H])([H])N=[N+]=[N-]
[H]N(C([H])([H])C([H])([H])OC1=C([H])C(OC([H])([H])[H])=C([H])C2=C1OC([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])O[C@@]2([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C3=C([H])C(C#N)=C([H])C([H])=C23)C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H])C1=N[C@@]2([H])N=C([H])N=C(N([H])C3=C([H])C4=C(C([H])=C3[H])N(N=C4[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2=C1C([H])([H])C([H])([H])[H]
[H]C1=NC2=C(OC3=C2C([H])=C([H])C([H])=N3)C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C(=O)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2C(=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])[C@@]([H])(C2([H])[H])[C@]1([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Br
ClC1=C(Cl)C(CN2C=NC(=O)C3=C2N=C(S3)N2CCOCC2)=CC=C1
[H]N(C(=O)C1=C([H])C([H])=C(N([H])C2=NC(OC([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C3N=C([H])N([H])C3=N2)C([H])=C1[H])C([H])([H])[H]
[H]C1=NC([H])=C(C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=NC(=NC2=C1C([H])([H])C([H])([H])N(C1=NC([H])=C([H])C([H])=C1C(F)(F)F)C([H])([H])C2([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C3(N([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C(N(N=C1C(F)(F)F)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C2N(C(=O)OC2=C1[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C(C(=O)N([H])C([H])([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])=C(Cl)C([H])=N1
[H]O[C@@]1([H])C([H])([H])N(C(=O)C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])N(C([H])=O)C3=C2C([H])=C([H])C([H])=C3[H])C1([H])[H]
[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N1C([H])=C([H])C(=C(N([H])S(=O)(=O)C([H])([H])[H])C1=O)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CN(C(=O)CN1C(=O)N2CCCC3=C2C1=CC(=C3)C1=CC=CC=C1)C1=CC=CC(Cl)=C1
[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C3=C2C2=C(C([H])=C([H])C([H])=C2[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])O[C@@]2(C3=C([H])C([H])=C([H])C([H])=C3C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1=C(C([H])=NC2=C(C([H])=C([H])C([H])=C12)[C@]1([H])OC1([H])[H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C(Cl)=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]N([H])C1=C(C(=O)N([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2N=C1C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])[C@]([H])(OC([H])([H])[H])[C@@]([H])(N([H])C(=O)C2=C([H])C([H])=C(Cl)S2)C1([H])[H])C1=C([H])C([H])=C(C([H])=C1F)N1C([H])=C([H])C([H])=C([H])C1=O
[H]OC([H])([H])C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C1=NN([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC([H])([H])C(N1C(=O)[C@]([H])(OC2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1(C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C2C([H])=C([H])C(OC3=C([H])C([H])=NC4=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C34)=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]12C(=C([H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(SN=N1)S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(S1)C(=O)N(C([H])=N2)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N([H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C1=NC([H])=C([H])S1
[H]OC(=O)[C@@]1([H])N(C(=O)C([H])([H])C2=C(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C(=C(N=C2C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)C(=O)N2C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])N2C1=NC([H])=C2C1=C([H])N([H])N=C1[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N1N=C2OC(=O)C([H])=C(C2=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OP(=O)(O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(SC2=NC([H])=NC(N3C([H])([H])C([H])([H])N(C(=O)C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])=C12)C([H])([H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C(Br)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C(SC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(S1)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N(C2=C([H])C([H])=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C2C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C2=C(N=C(O2)N2C([H])([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]C1=C(C([H])=C2C([H])=C3C(=NC2=C1[H])C([H])([H])C([H])([H])C3([H])[H])C(=O)[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C(F)=C([H])C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C2=C(C3=C([H])C([H])=C([H])O3)C(OC([H])([H])[H])=C([H])C([H])=C2C([H])=C1[H]
[H]OC1=C([H])C([H])=C(\N=N\C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(OC([H])([H])[C@@]2([H])C([H])([H])N(C(=O)C2(C([H])([H])[H])C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]3([H])[C@]([H])(C(=O)OC([H])([H])C([H])([H])[H])[C@@]3([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1C#N
[H]OC1=C(O[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3=C1C2=C([H])C1=C3C(=O)C([H])([H])C([H])([H])S1
[H]OC(=O)C1=C(C(=NN1C1=C([H])C(Cl)=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1
[H]N1C(=O)N(C2=C(N(C(=N2)N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
[H]OC(=O)C1=C(O[H])C([H])=C([H])C(=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(S1)C(=O)N([H])[C@]([H])(C(=O)C([H])([H])SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C(=O)O[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=N[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=C(\F)C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H])\C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])[C@@]([H])(C([H])([H])C([H])([H])N2C(=O)C([H])([H])S[C@]2([H])C2=C([H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N(C(=O)N([H])C([H])([H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
COC1=CC=CC2=C1N=C(C=C2C(O)=O)C1=CC=CC=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])OC([H])([H])C#CC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C(N([H])C(=N\C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])\N([H])C#N)=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])[C@]1(C2=C(Br)C(=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
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[H]N(C1=NC2=C(C#N)C([H])=NN2C(=N1)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C([H])N1[H])C1=NN([H])C([H])=C1C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC1(C#CC2=C([H])C3=C(C([H])=C2[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2O3)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]1([H])[C@@]([H])(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]2([H])[C@]1([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(C#N)C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])([H])C2([H])[H])=C1[H]
[H]OC(=O)C(\[H])=N\O[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])C2=C([H])SC(=N2)C([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O\C(=C(/N([H])\N=C(/[H])C1=C([H])C(=O)C(=O)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C2OC(=NC2=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C2=C(N=C(S2)C2=C([H])C([H])([H])N(C([H])([H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=C([H])N(C(=N1)C([H])([H])N1C([H])([H])C([H])([H])C2(C(=O)N(C3=C([H])C([H])=C(C([H])=C23)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C1=NC(=NC2=C(C#N)C([H])=NN12)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])C1=C([H])C2=C(C([H])=C1[H])N(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]N(\C(=N/S(=O)(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H])N1N=C([H])C2(C1([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@@]3(O[H])C3=C([H])C([H])=C4C(=C3[H])C([H])([H])[C@](C#N)(C(=O)OC([H])([H])C([H])([H])[H])C4([H])[H])[C@]1([H])C([H])([H])C2([H])[H]
COC1=C(OCCCOC2=CC=C(Br)C=C2)C2=C[N]3=C(C=C2C=C1)C1=CC2=C(OCO2)C=C1CC3
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(N1C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])=C(Cl)C([H])=C2[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])N1C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])=C(Cl)C([H])=C2[H]
[H]C([H])=C(C1=C([H])C([H])=C2N(C(=O)SC2=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]C([H])([H])C1=C(C(=O)ON1C(=O)N1C([H])([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(O[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1Cl
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC([H])=NC([H])=N2)=C1[H]
[H]C1=C(SC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]ON([H])C(=O)[C@@]([H])(C([H])([H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(N=C1C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C([H])C(Br)=C([H])C([H])=C1O2
[H]N([H])C1=NC2=C([H])C(=C([H])C([H])=C2[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])[C@]1(OC(=O)N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(\C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])=C1\C([H])([H])[C@@]2([H])N(C([H])([H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C2O[C@]3(C(=O)C([H])([H])C([H])([H])[C@@]4(OC([H])([H])C([H])([H])[H])[C@]5([H])N(C([H])([H])C([H])([H])C6=C([H])C([H])=C([H])C([H])=C6[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C([H])N=C12)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C([H])C([H])=C([H])N=C3C2([H])[H])C([H])([H])C1([H])[H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N(C1=O)C([H])([H])C(F)(F)F
[H]C1=C(C2=NSN=C2OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(O1)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(N([H])C2=C([H])N=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])=C1[H])C([H])=O
[H]N1C([H])=C(C2=C1C([H])=C([H])C(Br)=C2[H])C([H])([H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])SC2=C([H])C([H])=NC([H])=C2[H])=C1C([H])([H])[H])C(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C(=C1[H])N1N=C([H])C(Cl)=C(OC3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C1=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C(=O)C(F)(F)F
[H]O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(=C([H])C(N([H])[H])=C1[H])C(F)(F)F)C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])[H])C1=NC([H])=C([H])C(=C1[H])C1=NN([H])C(=O)N1C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C([H])C(OC3=C([H])C([H])=NC(N([H])C([H])([H])[H])=C3[H])=C([H])C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]1(OC([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=NC([H])=C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])[C@]2([H])O[C@]([H])(O[C@]12[H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=NC(=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N1C(=S)N([H])N=C1C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[123I]\C=C\CN1CCC(COC2=CC=C(C=C2)C#N)CC1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(\C(=N/C2=C(Cl)C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C2O[C@@]3([H])C4=C(C5=C(N4[H])C([H])=C([H])C(Br)=C5[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N1C2=C([H])C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2C2=C1C([H])=NC([H])([H])C2([H])[H]