[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OS(=O)(=O)O[H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C(C([H])=C([H])C(=N1)N(C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C2=C([H])C([H])=C(C([H])=C2C2=C1C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H])C(F)(F)F
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])N3C2=NC([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])[H])[C@@]([H])(N1C(=O)N(C2=C1C(F)=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(SC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)C(=O)C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[N@@+](C([H])([H])[H])(C([H])([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C#CC2=C([H])C3=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])=C3C2=C([H])C(O[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=C2C([H])=C(C([H])=C([H])C2=C([H])C([H])=C1[H])N1C(=O)N([H])N=C1C1=C([H])C(=NC([H])=C1[H])N([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@@](C#CC1=C([H])N2N=C(N=C2C(=N1)N([H])[H])C1=C([H])C([H])=C([H])O1)(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)S2)C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])=C([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(=N1)N([H])C([H])([H])[C@]1([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(SC2=C([H])C3=C(C([H])=C2[H])N(C([H])=C3[H])C([H])([H])C([H])([H])OC([H])([H])[H])C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C2C(=O)C([H])([H])[C@]([H])(OC2=C1C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(O[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)OC1=C([H])C2=C(C([H])=C1[H])N(C([H])([H])[H])[C@]1([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])[N@@+]1([O-])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=NC([H])=NC(=C1[H])N1C(=O)N(C(=O)C11C([H])([H])C([H])([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=N2)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)C([H])([H])OC([H])([H])[H]
[H]N1C([H])=C([H])C([H])=C2C([H])=C(N=C12)C([H])([H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N([H])C1=C(C([H])=NC(=N1)N([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)OC([H])([H])C1(C([H])([H])OC2=C3SC([H])=C([H])C3=NC([H])=N2)C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C([H])C(OC3=C([H])C([H])=NC([H])=C3[H])=C([H])C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C(C([H])([H])N2N=C([H])N=C2[H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])N=C1N([H])[H])C1=C([H])C([H])=C([H])S1
[H]C1=NC([H])=C([H])C(=C1[H])N1C([H])([H])[C@]2([H])C([H])([H])N(C(=O)C3([H])C([H])([H])N(C3([H])[H])S(=O)(=O)C3=C(Cl)C(Cl)=C([H])C([H])=C3[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]N(C(=O)O\N=C(\[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])S1)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])N(C1=C([H])SC([H])=C1[H])C(=NC([H])([H])C2([H])[H])C([H])([H])[H]
[H]ON(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C#CC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]N1C([H])=C([H])C2=C(N=C([H])N=C12)N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])OC([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@@]([H])(C([H])([H])C([H])([H])C2=C(C([H])=C(C3=C([H])C([H])=C(C([H])=C23)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C(F)=C1[H])C1=NN=C(O1)C1=C2N(C([H])=C(C2=C([H])C(F)=C1[H])C([H])([H])[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1I)[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)N(OC([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)\N=C(/N([H])C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@]2(O[H])C(=O)C([H])([H])SC2=NC3=C(S2)C([H])=C([H])C([H])=N3)[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C(=O)C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]12[H]
[H]N([H])C1=NC(N([H])[H])=C(C#C[C@@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])[H])C(=N1)C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C2=C(N=C([H])N=C2N([H])C2=C([H])C([H])=C([H])C(Br)=C2[H])C([H])=N1
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@]([H])(F)C([H])([H])[C@]1([H])C#N)C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C(F)=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N(C(=O)[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC(OC2=C([H])C([H])=C([H])C([H])=C2[H])=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]O[C@@](C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(I)=C(C([H])=C1OC([H])([H])[H])C(=O)OC([H])([H])C1=C([H])[C@@]2([H])[C@@]3([H])OC([H])([H])O[C@@]3(C(=C([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]2(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]2([H])C([H])=C(C(=O)[C@@]2(O[H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(S1)[C@@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C2([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(SC2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]S\C(=N/C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C2N([H])C([H])=C([H])C2=C1[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N(C1=C([H])C(OC2([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])C(F)(F)F
BrC1=C2C(NC3=C2C=CC2=C3NC=C2C=O)=CC=C1
CCOC1=CC=C(NC(=O)C23CC4CC(CC(C4)C2)C3)C=C1
[H]C1=NC(=C(O1)C1=C([H])N2C(=NN=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=C(F)C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]C1=C(SC(=N1)[C@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=NC(OC2=C([H])C(=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])N([H])[H])=C(F)C([H])=C1F
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])[C@@]1([H])C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2C([H])([H])C1([H])[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(Cl)C([H])=C([H])C(Cl)=C1[H]
[H]C1=C2N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(N(C3=NN(N=N3)C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C2=C([H])C(=C1[H])C(F)(F)F
[H]C1=C([H])C(F)=C2C(=C1[H])N(C1=C2[C@]([H])(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])F
[H]C1=C([H])C2=C(S1)C(=NC(=N2)C([H])([H])C([H])([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC1=C(N([H])C2=NSN=C2N([H])[C@@]([H])(C2=C([H])C(=C([H])O2)C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1N=C(C2=C1C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C1(C3=NC([H])([H])C([H])([H])O3)C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C(F)(F)F
[H]N(C1=NC([H])=C(C#N)C(=N1)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=NOC(=N2)C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C1=NC([H])=C2C([H])=C(C(=NC2=C1[H])N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C2[C@]([H])(OC([H])([H])[H])C([H])([H])[C@]3([H])[C@]4([H])C([H])([H])C([H])([H])C(=O)[C@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3([H])[C@]2(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C#CC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]O\C(=C(\C#N)C(=O)N([H])C1=C([H])C([H])=C(C(=C1[H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC(=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3OC([H])([H])C([H])([H])OC3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(I)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C(F)=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])S(=O)(=O)C([H])([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC(=C1C#CC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])N1C(=C(C(=O)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)[C@]([H])(N=C(N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])S(=O)(=O)O[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@]1([H])C([H])([H])O[C@@]([H])(O[C@]1([H])C1=C(O[H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H])\C2=C([H])N=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(OC2=NC([H])=NC(N([H])C3=C([H])C([H])=C(OC([H])([H])C4=C([H])C(F)=C([H])C([H])=C4[H])C(Cl)=C3[H])=C2[H])=C([H])C([H])=C1[H]
[H]N(C([H])=C1C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=O)C1=C(C(=O)OC([H])([H])C([H])([H])[H])C(=C(S1)C([H])([H])[H])C([H])([H])[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C#N)(C(F)(F)F)C(F)(F)F
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])[H])C2=O)=C1[H]
[H]\C(=C(\[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(N([H])C2=C([H])C([H])=C([H])C3=C([H])C(OC([H])([H])C4=C(ON=C4C4=C(Cl)C([H])=C([H])C([H])=C4Cl)C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C23)=C1[H]
[H]N(C1=NN([H])C2=C1C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C(=O)N([H])C1([H])C([H])([H])N(C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NN([H])C2=C1C([H])=NC(OC1=C(F)C([H])=C(F)C([H])=C1[H])=N2)C1([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C2=C(C([H])=NC([H])=C2[H])C([H])=C1[H]
[H]N1C(=NC2=C([H])C(=C(F)C([H])=C12)C(F)(F)F)C(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])=C1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])S2)C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1(C([H])([H])[H])C([H])([H])[C@]2([H])C3=C([H])C([H])=C([H])C([H])=C3[C@@]1([H])C1=C2C([H])=C([H])C([H])=C1[H])C1=NC([H])=C(S1)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(N1C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])=C([H])[H]
[H]N1C2=C(C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C1([H])[H])C([H])=C(C#N)C([H])=C2[H]
[H]N1C2=C([H])C([H])=C([H])N=C2N(C(=O)C([H])([H])[C@]2([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]N(C1=NC(=NC(=N1)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])C(=O)N1C([H])([H])C([H])([H])C(=C2C3=NC([H])=C(Cl)C([H])=C3C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C(Br)=C1C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C([H])([H])N(C(=O)[C@]([H])(C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C(=O)S[C@]([H])(C1=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC2=C(C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C(F)=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C(=O)N1C([H])([H])SC([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H])C2([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(OC(=O)C3=C([H])C([H])=NC([H])=C23)C([H])([H])C1([H])[H])C1=NC([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])F
[H]N1N=C(C2=NC([H])=C([H])S2)\C(=C(/[H])C2=C([H])N(C3=C2C([H])=C(Cl)C([H])=C3[H])C([H])([H])[H])C1=O
[H]N(\C(=N\C1=C([H])C([H])=C(C2=C([H])N=C([H])O2)C(OC([H])([H])[H])=C1[H])N([H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])SSC1([H])[H])C([H])([H])O[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([C@]([H])(C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(OC([H])([H])[H])C(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C2=NOC(=C2C(=O)N(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]N([H])C1=NC2=C([H])C(F)=C([H])C([H])=C2C([H])([H])N1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@@](=O)(O[H])OP(=O)(O[H])O[H])[C@@]1([H])O[H])N1C([H])=C([H])C(SC([H])([H])C([H])([H])[H])=NC1=O
[H]O[C@]([H])(C([H])([H])[H])C([H])([H])N([H])C1=NC2=C(N=C([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)C(SC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)(C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C1/C(=O)N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)C([H])([H])N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C(Cl)C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(O1)C(\[H])=C1/N([H])C(=O)N(C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N([C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C(C#N)=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C(ON=C1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N([H])C([H])([H])C(=O)N([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2O[C@]([H])(C([H])([H])N3C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])N4C(=O)N(C5=C(Cl)C([H])=C([H])C([H])=C5Cl)C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C([H])([H])OC2=C1[H]
[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])N(C([H])([H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=NC([H])=NC(=C2[H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(C2=NC(=C3N2N=C([H])N=C3N([H])[H])C2=C([H])C([H])=C(C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C(F)=C2[H])C1([H])[H]
[H]C1=NN(C(=C1[H])C1=C([H])C(=NC2=C(OC([H])([H])C3=C(Cl)C([H])=NC([H])=C3[H])C([H])=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])[H]
CCB(CC)OC(=O)[C@@H](N)CCCCNC(=S)NC1=C(F)C=C(C=C1)S(N)(=O)=O
[H]OC(=O)[C@]([H])(C([H])([H])C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N(C(=O)C1=C(N([H])[H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]1(OC([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])N=C1[H]
[H]N1C(=O)[C@@](C(=O)C2=C(Cl)C([H])=C(OC([H])([H])[H])C([H])=C12)(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N(C1=NN([H])C([H])=C1[H])C1=C(N2N=C([H])C([H])=C([H])C2=N1)C1=NC(=NC(N([H])C2=C([H])N(N=C2[H])[C@@]2([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])SC(=N1)C([H])([H])[H]
[H]OS(=O)(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(C(=O)OC([H])([H])[H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C(N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C1=NC([H])=C(N1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C1=C([H])C(=NC(=C1[H])C([H])([H])[H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])=[N+](C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1Cl)C(=O)C([H])([H])SC1=NC([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C(=O)N1[H]
[H]O[C@@]1([H])[C@@]([H])(O[H])[C@]([H])(N2C([H])=NC3=C(N=C(N=C23)N([H])C([H])([H])C([H])([H])C2=C([H])N(C([H])=N2)C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])N([H])C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(N=NN2C2=C1SC([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C(N([H])C2=NC([H])=C([H])C(=N2)N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N1C(=O)C(C2=C([H])C(F)=C(OC3=C([H])C([H])=NC4=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C34)C([H])=C2[H])=C(N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]ON(C([H])=O)[C@@]([H])(C([H])([H])N1C(=O)N([H])C(C1=O)(C([H])([H])[H])C([H])([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C([H])=C1SC([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1Br)C([H])([H])C([H])([H])C1=C(C(=O)C([H])([H])C([H])([H])N21)C([H])([H])[H]
COC[C@H](C)OC1=CC(CCC2=CC=C(F)C=C2)=CC(=C1)C(=O)NC1=NN(C)C=C1
[H]N(C([S-])=S)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C1=NN(C(=O)[C@]2([H])C([H])([H])C([H])=C([H])C([H])([H])[C@]12[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C(=O)C([H])([H])C1([H])[H]
[H]N(C(=O)C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H])C1=C(OC([H])([H])[H])C(Cl)=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(O[H])=NN=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N([H])C(=NC1=NC([H])=C(Cl)C([H])=C1\C([H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])N([H])[H]
[H]C1=C(Cl)C(=C([H])C(Cl)=C1S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=NC2=C([H])C([H])=C(N([H])C(=O)C(\[H])=C(/[H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)C2=C(C1=O)C1=C(N([H])C3=C1C([H])=C([H])C(F)=C3[H])C1=C2C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C([H])S2)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]N([H])[C@@]1([H])C(=O)[C@@]2([H])[C@@](C([H])([H])[H])(C([H])([H])C([H])([H])[C@@]3([H])C(=O)O[C@]([H])(C4=C([H])OC([H])=C4[H])C([H])([H])[C@]23C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C1([H])[H]
[H]N(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)O[C@]1([H])C([H])([H])N(C(=O)OC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]ON(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2S1
[H]C1=NN(\C(=N\S(=O)(=O)C2=C([H])C([H])=C([H])C(Cl)=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1(OC([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])[C@]2([H])C1=NC([H])=C([H])N1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C2=C(S1)S(=O)(=O)C1(C([H])([H])C1([H])[H])C([H])([H])N2[H]
[H]OC(=O)[C@@]([H])(OC1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])C(OC([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C1=C(N=C(O1)C1=C2C([H])=C([H])C(=NC2=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C(=O)N1C([H])([H])C([H])([H])C([H])(C(=N\OC([H])([H])[H])\C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(C(=O)N([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])C([H])([H])F
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1\C([H])=C(/[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(C2=C(C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=N3)=C2[H])C2=NN(N=N2)C([H])([H])C([H])([H])[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]2(C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=NC([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC(Cl)=C1C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])C([H])([H])C([H])([H])N([H])[H]
[H]N(C(=S)N([H])C([H])(C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])N=C(N=C1[H])C1=C([H])C([H])=NC2=C1C([H])=C(N2[H])C([H])([H])[H]
[H]N1C(=O)[C@@]2([H])N(C3=C([H])C(Cl)=C(Cl)C([H])=C13)C([H])([H])C([H])([H])N([H])C2([H])[H]
[H]OC1=NC(=NN1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
FC1=CC=C(C=C1)C(=O)NC1(CCC1)C1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=C([H])[C@]3([H])C(=C([H])C([H])([H])[C@@]4([H])[C@]5(C([H])([H])[H])C([H])([H])[C@@]6([H])O[C@@]([H])(C([H])([H])C(=O)[C@@](O[H])(C([H])([H])[H])[C@]6([H])[C@@]5(C([H])([H])[H])C([H])([H])C(=O)[C@@]34C([H])([H])[H])C(O[H])(C([H])([H])[H])C([H])([H])[H])C(C2=O)(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]S\C(=N/[C@]([H])(C(=O)OC([H])([H])C(=O)N([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(OC2=C(F)C(=C(F)C(OC3=C([H])C([H])=C([H])C(F)=C3[H])=N2)C([H])([H])[H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])N1C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C1=NC(N([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3N=C2C([H])([H])[H])=C([H])C([H])=N1)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])OC(=C([H])C1=O)C([H])([H])SC([H])([H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C([H])C(=C([H])C(=C2N=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])O1)C1=NC(=NC(Cl)=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])S1)[C@@]([H])(O[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C1=NN(C(=C1C1=C([H])C([H])=C(C([H])=C1C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=C(F)C=CC=C1CC1=C(C(=O)N2CCNCC2)C2=CC=CC(F)=C2N1C1=CC=CC=C1
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C([H])N([H])C4=C([H])C([H])=C([H])C(=C34)[C@@]2([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(O1)S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[N+]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])[C@]1([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C(=NC1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C1C(=C(N2[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])S1
[H]OC1=NC(=NC(=C1N(C([H])([H])C1=C([H])N(C(=O)N([H])C1=O)[C@]1([H])O[C@]([H])(C([H])([H])OP([O-])([O-])=O)[C@]([H])(O[H])C1([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@@]([H])(C([O-])=O)C([H])([H])C([H])([H])C([O-])=O)C([H])([H])[H])N([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(C#N)C(OC2=C([H])C([H])=C([H])C3=C2C([H])=C([H])C([H])=C3[H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H])S(=O)(=O)C([H])([H])[H]
OC(=O)C1=CC=C(C=C1)C1=CC=C(OCCC2=C(Cl)C=CC(=C2)C(O)(CCN2CCOCC2)C2=CC=C(Br)C=C2)C=C1
[H]O[C@@](C1=C([H])C([H])=C(C#N)C([H])=C1[H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C3=C(N=C([H])N3C([H])([H])[C@]12C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OP(=O)(O[H])C([H])(N([H])C1=NC(=C([H])S1)C([H])([H])[H])P(=O)(O[H])O[H]
[H]N([H])C1=C(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])N1C(=S)S\C(=C(/[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C3=C([H])C(=C([H])C([H])=C3[H])C(=O)O[H])C(Cl)=C2[H])C1=O
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])S(=O)(=O)N(C1=C([H])C2=C(SN=C2C([H])([H])[H])C([H])=C1Cl)C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(C2=C3N=C(N=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C4([H])C([H])([H])C4([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(SC2=C(C3=C(O2)N=C(N=C3N([H])[H])N([H])[H])C([H])([H])[H])C([H])=C1[H])C(=O)O[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[N+]([O-])=O
[H]OC(=O)C1=C([H])C(N([H])C(=O)C(\C#N)=C(/[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NN(C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(O[H])C(=C1[H])C(=O)N([H])C1=C([H])C([H])=C([H])C(C#C[H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(N([H])C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C2=NC([H])=NC(N([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C2[H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(C3=C([H])C([H])=C([H])C([H])=C3O[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])O2
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C([H])C(\C([H])=C(/[H])C([H])([H])N2C(=NC3=C2C([H])=C([H])C([H])=C3[H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=C1[H]
[H]N([H])C1=NC([H])=C([H])C(=C1[H])C1=C(C2=C([H])C(Cl)=C([H])C([H])=C2S1)C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C(OC(=O)C([H])([H])[H])C2=NON=C2C(OC(=O)C([H])([H])[H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C([H])C(I)=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=C(/[H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])\C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N(C(=O)[C@@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(F)=C(OC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C2=NC([H])=C([H])C([H])=C2C1=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C1=C([H])N(C([H])=N1)[C@]1([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=N2)C1([H])[H]
[H]OC(=O)C1=C(O[H])C([H])=C2C3=C(C4=C(N3[H])C([H])=C(C([H])=C4[H])C3=C([H])C(=C([H])C([H])=C3[H])C(F)(F)F)C([H])([H])C([H])([H])C2=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C2=C([H])N(N=C12)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N([H])C([H])([H])C1=C(C2=C(N=C1C([H])([H])[H])C(=O)N(C([H])([H])C(=O)OC([H])([H])[H])C2([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])N(N=C12)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C#CC([H])([H])N1C([H])([H])C2=C(N([H])[H])C3=C([H])C([H])=C([H])C([H])=C3N=C2C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)N([H])C2=C([H])C3=C(N=C2[H])C([H])=C([H])C([H])=C3[H])C1=O
[H]OC1=C([H])C(O[H])=C(C([H])=C1[H])C1=C(O[H])C(=O)C2=C(O1)C([H])=C(O[H])C([H])=C2O[H]
[H]N(C(=O)C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])SSC([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])[C@]([H])(N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])[C@@]1([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
ON(=O)C1=C(C=C2NN=C(\C=C\C3=CC=CC=C3)C2=C1)N1CCCC1
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC(=O)C([H])([H])N([H])C(=O)C([H])([H])C2=C([H])C([H])=C(N([H])C3=C([H])C([H])=NC(=C3[H])C(F)(F)F)C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])C2=C(OC([H])([H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])=C([H])C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])O1)C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(\C([H])=C1\S\C(N(C1=O)C([H])([H])C([H])([H])[H])=C(\C#N)C(=O)N([H])C([H])([H])C([H])(F)F)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=N1)C([H])([H])[C@@]1([H])\C(=C(\[H])C([H])([H])[H])[C@]2(N([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=NC(OC2=C([H])C([H])=C([H])C([H])=C2[H])=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N([H])S(=O)(=O)C1=C(OC2=C(C([H])=NC([H])=C2[H])S(=O)(=O)N([H])[H])C([H])=C([H])N=C1[H]
[H]C1=C([H])C(C2=C([H])C(=C(SC3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])=C2[H])S([O-])(=O)=O)=C(C([H])=C1[H])C([H])([H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C(C#N)C(=N1)N([H])[H])C([H])([H])[C@]([H])(N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(N([H])C(=N[H])N([H])[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])O[C@]1([H])OC([H])([H])[C@@]([H])(C([H])([H])OC(=O)N(C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=[N+]2C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N([H])C1=NC([H])=C(N=C1C([H])([H])N([H])C(=S)N([H])C1=C([H])C([H])=C2N([H])C(=O)OC2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([C@]1([H])C([H])([H])C([H])([H])[C@](C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])N=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])OC([H])([H])[H]
[H]N(C(=O)C1=C(N([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])=NN1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C2=C(C(=O)N(C(=O)N2C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2F)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])[C@@]2([H])[C@@]3([H])[C@@](OC(=O)C([H])([H])C([H])([H])C([H])([H])[H])([C@]([H])(OC(=O)C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]2(O[H])[C@]2([H])C([H])=C(C(=O)[C@@]2([H])C1([H])[H])C([H])([H])[H])C3(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC([H])([H])[C@]([H])(O1)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]S\C(=N/C([H])([H])C([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1SC([H])=C([H])C1=O)C1=C([H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])C2=C1[H]
[H]N(C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])N=C1[H]
[H]ON([H])C(=O)[C@@](C([H])([H])[H])(C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
COC1=C(CSC2=NC3=C(SC(N)=N3)C(N[C@@H](CO)CC(C)C)=N2)C=CC=C1
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(Cl)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC(=C([H])C2=NC([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=N[C@@](C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])C(=O)C2=C([H])N=C(OC([H])([H])C([H])([H])C([H])=C([H])[H])C([H])=N2)(C([H])([H])[H])C([H])([H])C([H])([H])S1
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C2=C([H])C([H])=C(O[H])C(C3=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])[H])=C3[H])=C2C([H])=C1[H]
[H]OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(C#N)=C([H])C([H])=C2N1C([H])([H])C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1OC([H])([H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C3=C1C([H])=C([H])C([H])=C3[H])C(=O)N([H])[H])C([H])([H])C1=C(C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]C1=C([H])N2C(=NC(=C2C2=C([H])C(OC3=C([H])C(=C([H])C([H])=C3[H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C(F)(F)F
[H]N1[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(OC(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]N([H])C(=O)C([H])([H])OC1=C([H])C2=C([H])C([H])=C(N=C2C([H])=C1[H])C(\[H])=C(/[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H]
[H]N1N=C(C2=C(C1=O)C([H])([H])C([H])([H])C([H])([H])N2[H])C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C(=O)C([H])=C1C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H])[C@@]([H])(C1=C([H])N=C([H])N1C([H])([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=NC2=C(S1)C([H])=C([H])C(=C2[H])C(F)(F)F
[H]N1C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2C2=C1C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C2SC3=C(N=C(N([H])C3=O)C([H])([H])N3C([H])([H])C([H])([H])[C@]([H])(O[H])C3([H])[H])C2=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=[N+]([O-])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1N([H])S(=O)(=O)C([H])([H])[H])C1=C(C([H])=C([H])C([H])=N1)C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC([H])([H])[C@@]1([H])C([H])([H])N2C3=C([H])C([H])=C(C([H])=O)C([H])=C3C3=C2C2=C(C4=C(C([H])=C([H])C(Br)=C4[H])N2C1([H])[H])C1=C3C([H])([H])N([H])C1=O
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@](C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])(C([H])([H])C(C1=C([H])C(F)=C([H])C([H])=C1OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]N([H])C1=NC2=C(OC3=C([H])C([H])=C([H])C(Cl)=C23)C(=N1)N1C([H])([H])[C@@]2([H])N([H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N(C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]1([H])C([H])([H])N(C(=O)N([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1(C([H])([H])OC2=C([H])C([H])=C([H])C3=C([H])C([H])=C(N=C23)C2=NN=C3C([H])=C([H])C([H])=C([H])N23)C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C1N(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(OC2=C([H])C([H])=C([H])C3=C2C([H])=NS3)C([H])=C1[H]
[H]OC(=O)C(\[H])=C(\C1=C([H])C2=C(SC([H])=C2C2=C([H])C(=C([H])C(=C2O[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NC(F)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1S(=O)(=O)C2=C(C([H])=C([H])C([H])=C2[H])S1(=O)=O
[H]N(C(=O)C([H])([H])O[C@@]12C([H])([H])C([H])([H])[C@@](C([H])([H])[H])(C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(C#N)=C([H])C([H])=C2O1
[H]C1=C([H])C([H])=C(C(Br)=C1[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C([H])C(=NC([H])=N2)C2=C([H])N=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[C@]1([H])C1=C([H])C(F)=C(F)C([H])=C1F
[H]N(\C(=N/C(=O)C1=C([H])C([H])=C(F)C(F)=C1[H])N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CC(C)C[C@H](CO)NC1=NC(S[C@@H](C)C2=NC=CC(Cl)=C2)=NC2=C1SC(=O)N2
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C(=O)SC3=C([H])C([H])=C(Cl)C([H])=C23)C([H])([H])C1([H])[H])C1=NC([H])=C([H])S1
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
CC(=O)N1N=C(CC1C1=CC=CC=C1)C1=CC2=CC=CC=C2OC1=O
[H]C1=C(Br)C([H])=C2C(=N1)[C@@]([H])(N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C3=C([H])C([H])=[N+]([O-])C([H])=C3[H])C([H])([H])C1([H])[H])C1=C(C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=NC3=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C([H])=C3C(N([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C3[H])=C2C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C2=C(C#N)C3=NN=C(N3C([H])=C2[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1O2)C([H])([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C(=O)N([H])C1=NC([H])=C(S1)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]2(O[C@]([H])(OC([H])([H])[H])C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC1=C(I)C([H])=C(C([H])=C1I)C([H])([H])C1=C(N=C(N=C1[H])N([H])[H])N([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])\N=C(/S[H])N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N=C(N([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C2C(N=C([H])N=C2N2C([H])([H])C([H])([H])N(C(=O)N([H])C3=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])=C1[H]
[H]OC([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C2=NC([H])=C(C#N)C(=N2)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[H])C([H])=C1[H]
[H]O[C@@]1([H])N([H])C([H])([H])C([H])([H])N(C2=NC([H])=C3C([H])=C(C4=C([H])C([H])=C([H])C([H])=C4[H])C(=NC3=N2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=NN=C(N3[H])C3=NC([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=NC([H])([H])C([H])([H])N1C(=C2[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(SC([H])([H])C([H])([H])[H])=NN=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)[C@]2([H])N([H])C(=O)N([H])C(=O)C2([H])[H])C([H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])O[H])C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])N([H])[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)N([H])[H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C1=NC(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C1=C([H])C2=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C2([H])[H]
[H]N([H])C(=NC(=O)C1=C(OC(=N1)C1=C([H])C(Cl)=C([H])C([H])=C1Cl)C([H])([H])[H])N([H])[H]
[H]N(C1=C([H])C2=C(OC([H])([H])C2=O)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(N([H])C2=C3C([H])=NN(C3=NC([H])=N2)C2=C([H])C([H])=C(F)C([H])=C2[H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])S2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC(=NC(=C2[H])C(F)(F)F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])OC4=C([H])C([H])=C(F)C([H])=C34)[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C3N([H])C4=C(C([H])=C([H])C([H])=C4[H])C3=C2[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]N=C(N([H])[H])N([H])C(=O)C1=C([H])C2=C(C([H])=C([H])C([H])=C2S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=NN(C(=C2C([H])([H])C#N)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N1C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(C(C(=O)SC([H])([H])C([H])([H])OC([H])([H])[H])=C1C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1O[C@@]1([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C2N=NN(C2=N1)C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]O[C@@](C(=O)N([H])[C@@]([H])(C1=C(F)C([H])=C(C([H])=N1)C1=C([H])C(Cl)=C([H])C(Cl)=C1C1=NC(=NO1)C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C(F)(F)F
[H]OC([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])N1[H])C1=C(C([H])=NC(=N1)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=NC2=C(N1[H])C([H])=C([H])C(=C2[H])C(N([H])[H])=[N+]([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])[H])C([H])([H])N([H])C2=C([H])C([H])=C(OC([H])(F)F)C([H])=C2[H])=N1
[H]OC1=NSC(N([H])C2=C([H])C(Br)=C([H])C([H])=C2[H])=C1C#N
[H]N(C(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)C([H])([H])O[C@@]1([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])[C@]([H])(N([H])[H])C([H])([H])[C@]([H])(C2=C(C([H])=NC([H])=C2[H])C([H])([H])C(=O)C2=C(N([H])[H])C([H])=C([H])C(=N2)C2=C(F)C([H])=C([H])C([H])=C2F)C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N1C(=O)N(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C(SC([H])([H])C([H])([H])[C@@]4([H])OC([H])([H])C([H])([H])OC4([H])[H])N=C23)N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])C1=NC2=C(S1)C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C21
[H]N([H])C1=C([H])C([H])=NC(=C1[H])C1=C(SC(=N1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])[H])[C@]1([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C2C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])C([H])([H])O[H])=C([H])C2=NC2=C1C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])O[H])C([H])=C2[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]1([H])N(C(=O)C([H])([H])C([H])([H])S[H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])OC([H])([H])[H]
[H]O[C@]1(C(=O)O[C@]([H])(C([H])=C(C([H])([H])[H])C([H])([H])[H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]2([H])[C@]1([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(OC(=O)C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])OC(=O)N1C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C1=NC([H])=NC(=C1C#CC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H][C@]12CC[C@H](N1C(=O)[C@H](CC[C@H](O)C2)NC(=O)[C@H](C)NC)C(=O)NC(C1=CC=CC=C1)C1=CC=CC=C1
[Na+].[Na+].CC1=CC(=CC=C1NC1=CC(=C(N)C2=C1C(=O)C1=CC=CC=C1C2=O)S([O-])(=O)=O)C1=CC=C(NC2=CC(=C(N)C3=C2C(=O)C2=CC=CC=C2C3=O)S([O-])(=O)=O)C(C)=C1
[H]C([H])=C([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])=C([H])[H])C([H])([H])C1([H])[H]
[H]N(\C([H])=C(/[H])C(=O)C1=C([H])C([H])=C([H])S1)C1=C([H])C(=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C1=C([H])C(F)=C(C([H])=C1[H])C1=NC2=C(S1)N=C(C([H])=C2[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC3=C(N=C([H])N3C([H])(C([H])([H])[H])C([H])([H])[H])C(=N2)N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])S2)C([H])([H])C1([H])[H]
[H]C#C[C@@]1([H])N(C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(=O)N([H])[C@@]2([H])C([H])([H])[C@]2([H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])[C@@]([H])(F)C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C(=O)OC2=C1C([H])=C([H])C(Cl)=C2[H]
[H]OC(=O)C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1C(=O)O[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]N1C([H])([H])C([H])([H])[C@]([H])(OC2=C([H])C([H])=C([H])C3=C([H])C([H])=C(N=C23)C2=NN=C3C([H])=C(Cl)C([H])=C([H])N23)[C@]([H])(F)C1([H])[H]
[H]N(C1=NC(=NC(=N1)N([H])C([H])([H])[H])N([H])C([H])([H])[H])C1=C([H])C([H])=C(C2=C([H])N=C([H])O2)C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])N([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(SC([H])([H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])(C1([H])[H])[C@@]([H])(OC1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N/C(=O)C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[N+]1=C(C([H])=C(\C([H])=C(/[H])C2=C([H])C3=C4N(C([H])([H])C([H])([H])C([H])([H])C4=C2[H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])[H])\N([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C#CC2=C([H])C([H])=C([H])C(C#C[H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C(N([H])C2=C([H])C([H])=NN2[C@]1([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])SC([H])=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C(C#N)C([H])=C3C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C(=O)O[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)[C@@]1([H])C([H])([H])[C@]11C([H])([H])C([H])([H])N(C2=C([H])C(F)=C([H])C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(I)=C(N([H])C(=O)C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@@]3([H])[C@]4([H])C(=O)C([H])([H])[C@]5([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[C@]5(C([H])([H])[H])[C@@]4([H])C([H])([H])C(=O)[C@]23C([H])([H])[H])C([H])=C1[H]
CCCCN(C(=O)C1=CC=C(C=C1)C(F)(F)F)C1=NN=C(S1)C1=C2C(Cl)=CN(CCC(O)=O)C2=CC=C1
[H]OC1=C([H])C(=NC2=NC([H])=C([H])C([H])=C12)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(C([H])=C([H])C(=C2[H])C([H])([H])[H])[N+]([O-])=O)C([H])=C1[H]
[H]N(C1=C2N=C([H])N([H])C2=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])SC1=NC(=C(N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C2=C(N([H])C3=C2C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C3=C(C([H])=C(C#N)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C3=C([H])C([H])=C([H])N=C23)C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2F)N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C1=C([H])N2C([H])=C(C([H])=C([H])C2=N1)C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C(SC([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=NC([H])=C(C([H])=C2C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N([H])C(C(=O)N([H])[C@@]([H])(C1=NN=C(N1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H])S(=O)(=O)C(F)(F)F
COC1=CC2=C(CN(C[C@]3(NC(=O)NC3=O)C#CC3=CC4=C(C=C3)C(C)=NN4)C2=O)C=C1
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]ON(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C#CC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])C(=O)N(C2=C([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2(C(=O)OC([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
CC(=O)NC1=C(OC[C@@H](O)CN2CCC3(CC4=CC(Cl)=CC=C4O3)CC2)C=C(O)C=C1
[H]OC1=C([H])C([H])=C([H])C(=C1[H])N1N=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
CC(NC(=O)C1(N)CCN(CC1)C1=NC=NC2=C1C=CN2)C1=CC=CC=C1
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])=NC2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(O1)C([H])=C([H])C(=C2[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C([H])N(C2=C1C([H])=C(N([H])C(=O)OC1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1Br)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[C@@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C(OC([H])(F)F)C(OC([H])(F)F)=C1[H])C([H])([H])C1=C([H])C([H])=[N+]([O-])C([H])=C1[H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(S1)C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])N([C@]([H])(C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C3=C([H])C([H])=C4OC([H])([H])OC4=C3[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C1C(=C([H])C(Cl)=C2[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C(=O)[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=NSN=C12
[H]OC1=C([H])C([H])=C2N([H])C([H])=C(\C([H])=N\N([H])C(=N[H])N([H])[H])C2=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]1([H])OC(=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(O[H])[C@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)O[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C(F)=C([H])C(F)=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=CC2=C3C=C1OC1=C4OCOC4=CC4=C1[C@H](CC1=CC=CC(OC5=C(OC)C=CC(C[C@H]3N(C)CC2)=C5)=C1)N(C)CC4
[H]N1C([H])=C(\C([H])=C2/N=C(N([H])C2=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])N=C12
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(OC([H])(F)F)C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(OC(=O)N(C2=C([H])C(=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2[H])C2=NC3=NC([H])=NC(N([H])[H])=C3C(=C2[H])C2=C([H])C(Br)=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C#N
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N(N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N(C(=O)N([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N(C(=O)C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C(=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N([H])C1=C(C(=O)N([H])N2C3=C([H])C([H])=C(Cl)C([H])=C3N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C2C([H])=C([H])C([H])=C3[H])C(Cl)=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC2=C(I)C([H])=C(C([H])=C2I)C([H])([H])C([H])([H])N([H])[H])C([H])=C1I
[H]N([H])C1=NON=C1C1=NC2=C([H])N=C([H])C(C(=O)N3C([H])([H])C([H])([H])[C@@]([H])(N([H])[H])C3([H])[H])=C2N1C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C2=NC([H])=C([H])N=C2C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])\C(=N\C2=C3C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C3=NC([H])=N2)C(=O)C(Cl)=C1OC([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])OC(=O)N2C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C2=C([H])N(N=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(C(=O)N([H])[C@@]([H])(C1=NN=C(N1C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(=C2[H])N1C([H])=NN=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C2=NC(N([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C3N=C(N=C3N2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)N(C(F)=C(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]N=C(N([H])[H])C1=C([H])C2=C(N([H])C([H])=C2C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C(N([H])C2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C2=NC(=C([H])C(=N2)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)[C@@]3([H])N(C(=O)C2([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])C1=C(Br)C(OC(F)(F)F)=C([H])C(Br)=C1[H])N(C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(C([H])=C(Cl)C([H])=C2[H])[N+]([O-])=O)C([H])=C1[H]
[H]N([H])C1=C([H])C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])S(=O)(=O)N([H])[H])=C(C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Br)C([H])=N1
[H]N(C([H])([H])C1=NN([H])N=N1)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]OC1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C(=O)[C@]([H])(N([H])C1=C([H])C([H])=C(C([H])=C1Cl)C([H])([H])[H])C1=C(Br)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(\C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])=C1\C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])OC([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]3([H])N(C(=O)[C@]4([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[C@]([H])(O[H])C3([H])[H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])O[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]N(C1=NC(=C([H])O1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C1=NC(=C(O1)C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C2C([H])=C(C(=O)OC([H])([H])[H])C(=O)OC2=C1[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C(=N\OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])\C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C2=C(C3=C(S2)N2C(=NN=C2[C@]([H])(N=C3C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C2=C(N(N=C2[H])C2=NC([H])=C([H])C([H])=C2C(F)(F)F)N(C1=O)C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])=NC(=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C2=C([H])C(=C([H])C([H])=C2N1[H])C(=N[H])N([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(\C([H])=C(/[H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N1C(=O)N([H])C(N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C(C1=O)C([H])([H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])ON([H])C(=O)C1=C(N([H])C2=C([H])C([H])=C(I)C([H])=C2F)C(F)=C(F)C(=C1[H])C([H])([H])N(OC([H])([H])[H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2O[C@]3([H])C(=O)\C(=C(\[H])C4=C([H])C([H])=C5C([H])=C([H])C([H])=C([H])C5=C4[H])C([H])([H])[C@@]4(O[H])[C@]5([H])C([H])([H])C(C([H])=C1[H])=C2[C@]34C([H])([H])C([H])([H])[N@@+]5([H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N([H])C1=C2C(=O)C3=C(N([H])N=C3C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(S1)C([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C(F)=C([H])C([H])=C12)C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C(C2=O)C(=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C(OC1=C([H])C([H])=C(C([H])=O)C([H])=C1[H])=C2[H])C([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C(=O)[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)C(=O)C([H])=C2C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C(Cl)=NC([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])=C1[H])C([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])N(C(=O)C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C2=C(N=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(F)=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=NC([H])=C([H])C([H])=C2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])[C@@]([H])(N([H])[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1C([H])=C(N=C1C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(N([H])C([H])([H])N2N=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])=C1[H]
[H]OC1=C(Br)C([H])=C(\C([H])=C(/[H])C(=O)C2=C([H])C([H])=C(OC(=O)C3=C([H])C([H])=C(C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C1=C([H])C2=C(OC([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])\C2=C(/[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])N([H])[C@]([H])(C(=O)OC1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]1([H])O[C@]2(O[C@](C(=O)O[H])(C([H])([H])C2([H])[H])[C@]1(O[H])C(=O)O[H])C([H])([H])C([H])([H])C(=C([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N=C1[H])C1=NC([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])[C@]1([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
COC1=CC2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=CC=C(C=C3)C(O)(O)C(F)(F)F)C2=O)C=C1
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(Br)SC(=C1[H])C(=O)C([H])([H])Br
[H]C1=C([H])C(=C([H])C([H])=C1C#N)C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C1=C2N=C(N(C2=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C([H])(C1([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(C(=O)N([H])C2=C([H])C([H])=C(Cl)C([H])=N2)=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])N=C(SC2=C([H])C3=C(C([H])=C2C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N([H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C1=NC([H])=C([H])S1
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])O[H])C([H])([H])S[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C1=C2C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)N(C2=C([H])C(=C([H])C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C(=N2)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C2C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C2=C1C1=NC2=C([H])C(=C([H])C([H])=C2N1[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
O[N]1=CC=CC(=C1)C1=NN2C(=C1)N=CC=C2C1=CC(OCC2CC2)=C(OC(F)F)C=C1
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C(=O)C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C([H])=C2N1[H])[C@]1([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(C#N)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]OP(=O)(O[H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C1=NC(=NO1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]N([H])C1=NC([H])=C(Cl)N=C1C([H])([H])N([H])C(=S)N([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(F)=C(F)C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C2=NC([H])=C(C(=N2)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(N1C(=O)[C@@](C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])N(C2=C([H])C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C3([H])[H])C2=C(C([H])=NC(=N2)N([H])C2=C([H])C(=C([H])C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=O
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C(C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]N1C(=O)N([H])C(=O)C(OC2=C([H])C([H])=C(OC3=C([H])C([H])=C(C([H])=C3[H])C3=NC(=C([H])O3)C3=C([H])C([H])=C([H])C([H])=C3F)C([H])=C2[H])(C1=O)C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])[C@@]6([H])O[C@]([H])(C([H])([H])C6([H])[H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C(Cl)N=C2C([H])=C1[H])C(=O)O[H]
[H]N1C(=NC2=C(C([H])=C(C([H])=C12)C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])SC(=NC1=O)N([H])\N=C(/[H])C1=C([H])C(OC([H])([H])C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])N1N=C([H])N=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])N2C([H])=C([H])C([H])=C2C1([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C(N=C1C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])=C([H])C(=C2[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])S(=O)(=O)N1C2=C([H])C(=C([H])C([H])=C2C(=O)C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C(=NN1C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=NC(=C2N1C1=NC(OC([H])([H])[H])=C([H])C([H])=C1N=C2C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1(C([H])([H])N([H])C(=O)N([H])C2=C(C([H])=C([H])C([H])=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])[C@@]2(O[C@](C([H])([H])[H])(C1([H])[H])[C@@]1([H])C(=O)N(C(=O)[C@@]21[H])C1=C([H])C([H])=C(C#N)C(=C1[H])C(F)(F)F)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(OC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(F)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C2N(C(=NC2=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])OC([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C1=C([H])C(=C([H])C3=C1[C@]([H])(N(C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)N1C2=C(SC([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C2OC(SC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])N3C(=O)C(C3=O)(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=NC2=C1[H]
[H]OC(=O)C1=C(C(=NN1C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])SC([H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1Cl
[H]N(C(=O)C1=C2C([H])=C([H])C(OC3=C([H])C([H])=NC4=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C34)=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)[C@@](OC2([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]OC(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(\C(=N/C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=NC2=C([H])C(=C([H])C([H])=C12)C(F)(F)F)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(=C([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=NN(N=N1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])C1=NC2=C(C([H])=C3C(=N2)C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C3([H])[H])C(=N1)N([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C#CC1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])C(=O)[C@]1([H])[C@]([H])(N([H])C2=NC(=NC([H])=C2Cl)N([H])C2=C([H])N(N=C2[H])C([H])([H])C([H])([H])[H])[C@@]2([H])C([H])=C([H])[C@]1([H])C2([H])[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C1OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1C2=O)C([H])([H])[H]
CC1=C(C=C2C(=C1)C(C)(C)CCC2(C)C)N1C2=CC=C(C=C2N=C1C(F)(F)F)C(O)=O
[H]OC(=O)C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(S2)C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(/C1=C([H])C2=C(OC([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(OS(=O)(=O)O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C(F)=C(C([H])=C1[H])N1C(=O)[C@]([H])(N(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C3C([H])=C(Cl)C([H])=C([H])C3=C2[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)C(=C(I)I)C1=C([H])C([H])=C([H])C([H])=C21
[H]N([H])C1=NC(=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(N([H])[H])=C(C([H])=C1C([H])([H])[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NSC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=N[C@@](C2=C([H])C([H])=C([H])C(F)=C12)(C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=C([H])N=C1[H])C1=C([H])N(C(=O)C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[H])[C@]([H])(N2C([H])=NC3=C(N=C(N=C23)N([H])C([H])([H])C([H])([H])C2=C([H])N(C([H])=N2)C([H])([H])C([H])([H])[H])N([H])C([H])([H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])N1N=NC(=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=C(Cl)C([H])=C(C(=O)N([H])[C@]2([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C(F)=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])N(C(=O)C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1F)[C@]1([H])N([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C3C(=NC([H])=N2)N([H])C([H])=C13
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC(C2=C([H])C([H])=C([H])C([H])=N2)=C(C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C1=NC([H])=C(C(=N1)N([H])C([H])([H])[H])C(F)(F)F)C1=C(Cl)C([H])=C(C([H])=C1[H])C1=NN=NN1C([H])([H])[H]
[H]OC([H])([H])C#CC([H])([H])C([H])([H])C([H])([H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C(C(=O)C(=C(C1=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N(C1=C(C(=O)C([H])([H])[H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C#N)C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])[C@@]([H])(N([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C1([H])[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]C1=C(SC(=C1[H])C1=C([H])C2=NC([H])=C([H])N=C2C([H])=C1[H])C(=O)C(F)(F)F
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[C@]1([H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=N1)C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C(SC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])N=C23)N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=NOC(=C1[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N2C([H])=NC(=C2C([H])([H])N2C(=O)C(N([H])S(=O)(=O)C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]C#CC([H])([H])N([H])[C@]1([H])C2=C([H])C(OC(=O)N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]1(OC(=O)\C(=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C1([H])[H])C([H])([H])OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC1=C(N=C2N1C([H])=C(N=C2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=NO1)C1=NC2=C([H])C(=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H])C([H])([H])N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
NC(=O)C1=C(NC(=C1)C1=CC=NC=C1)C1=CC(=CC=C1)[N+]([O-])=O
[H]OC(=O)C1=C(N([H])C(\C([H])=C2/C(=O)N([H])C3=C([H])C(N([H])C(=O)N([H])C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C4[H])=C([H])C([H])=C23)=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(Cl)=C3Cl)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C(=NC2([H])[H])C([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=N1
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C2=C(N=C(N([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(N([H])C2=C([H])C([H])=C3SC(=C(C3=C2[H])C([H])([H])[H])C2=NC(=NC([H])=C2[H])N([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC([H])([H])[H])C2=C(O[H])C([H])=C(O[H])C([H])=C2C1=O
[H]OC1(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=N[C@@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])SC([H])([H])C1([H])[H]
[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(C2=NC(SC([H])([H])C([H])([H])[H])=NC(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C12)C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(N=C1N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C#N)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(C(=O)C(=O)C([H])=C2[C@]23C([H])([H])C([H])([H])N4C([H])([H])C5=C([H])C([H])([H])O[C@@]([H])(C([H])([H])C(=O)OC([H])([H])[H])[C@@]([H])([C@@]12[H])[C@]5([H])C([H])([H])[C@]34[H])[N+]([O-])=O
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])C([H])([H])N(C1=C([H])C(Cl)=C(C#N)C([H])=C1[H])[C@]([H])(C1=NN=NN1C([H])([H])[H])C([H])([H])[H]
[H]C1=C2OC(=O)C([H])([H])[C@]([H])(C3=C([H])C(OC([H])([H])[H])=C(OC(=O)C([H])([H])[H])C(OC([H])([H])[H])=C3[H])C2=C([H])C2=C1OC([H])([H])O2
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=NOC3=C2C([H])=C([H])C2=C([H])C(O[H])=C([H])C([H])=C32)C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C2=C(N([H])C3=C2C([H])=C(C([H])=C3[H])C([H])([H])[H])[C@]1([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C2O[C@]1([H])C(F)(F)F
[H]N(C(=O)[C@]([H])(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C3(OC([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C1=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)O[C@@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C([H])([H])OC(=O)C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]OC([H])([H])C1=C([H])N(N=C1C(F)(F)F)C([H])([H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H])C2([H])[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C(F)=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(N=C(C([H])=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(=NC3=C1[C@@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C(C(=O)OC([H])([H])C([H])([H])[H])=C(N3[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1(N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NC2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C4=C(OC([H])([H])O4)C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)C1=C([H])C2=C(OC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C([H])N(N=N2)C([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3S2)=C1[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C1=C([H])C(C2=NN3C4=C2N=C(C([H])=C4N(C([H])([H])C3([H])[H])C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]O[C@]([H])(C([H])([H])Cl)C([H])([H])N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)[C@]2([H])C([H])=C([H])C([H])([H])N3N2C(=O)N(C3=O)[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])SC2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(O[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(SC1=NC(N([H])C2=C(C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])=C([H])C(Cl)=N1)C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C([H])=C(C(=S)N([H])[H])C(=O)OC2=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C(N([H])C2=C([H])C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=O)=C1[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])[C@]4([H])[C@]5(C([H])([H])[C@@]35C(=O)C([H])([H])[C@]2(C([H])([H])[H])[C@@]1([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])N=C(C([H])=C([H])[C@@]41C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(C2=C([H])N=C(N2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C(F)C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])SSC(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(N([H])C1=O)C(=O)O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]OC([H])([H])[C@@]([H])(N([H])C1=C(C([H])=NC([H])=C1[H])S(=O)(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])SC(=N1)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(Br)C2=C1C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C2([H])[H]
[H]C1=NC2=C(C([H])=C1[H])C(=O)C(=O)C1=C2C([H])=C([H])C([H])=C1[H]
[H]OC1=C(SC(=N1)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]C1=NC(=C2N1C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C21)C1=C([H])C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(=S)N([H])C2=C1C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3N=C(N([H])C3=C([H])C([H])=C2[H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=C([H])N(N=N1)C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)N([H])[C@]2([H])N(C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C3=C1C([H])=C([H])C([H])=C3[H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N1C(SC([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=NC2=C([H])C([H])=C(C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C([H])C([H])=C2C([H])=C(C([H])=NC2=C1C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(N([H])C2=C3N=NN(C3=NC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(N([H])C2=NC3=C(N=NN3C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=N2)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C(N([H])C(=N/C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])\N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C1(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=N2)C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C1=NC([H])=C(N1[H])C1=C([H])C([H])=C([H])C(F)=C1[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C(OC([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])N=C(C([H])=N1)C1=C([H])N(N=C1[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(C([H])([H])C1=C([H])C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=NS2)N1C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])[C@@]2([H])C([H])([H])N2C(=O)C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])[H])[C@@]([H])(N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(\N=C1/C(=O)N([H])N=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(C2=NON=C12)[N+]([O-])=O
[H]N1C(=O)C([H])([H])OC2=C([H])C([H])=C(C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N2C(=NC(=C2C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]N(N=C1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C1=NC([H])(C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])(N1[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])SC([H])=C1[H]
[H]N(C(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=[N+]([O-])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]C1=NC(=C([H])C(=C1[H])C([H])([H])N1C(=O)N(C(=O)C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(SC(F)(F)F)C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C1=NC(N([H])[H])=C2N=C([H])N(C2=N1)[C@]1([H])O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])[C@@]1([H])O[H]
[H]\C(=C1/C2=C([H])C([H])=C(F)C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC1=C(I)C([H])=C(OC(=O)OC([H])([H])C2=C([H])[C@@]3([H])[C@@]4([H])O[C@@]5(O[C@@]4(C(=C([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]3(O5)[C@]3([H])C([H])=C(C(=O)[C@@]3(O[H])C2([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1OC([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C(Cl)=C([H])C([H])=C12)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC1=NC2=C([H])C([H])=C([H])C([H])=C2C2=N[C@@]([H])(C(=O)N12)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])O1)C([H])([H])C1=C([H])C([H])=C([H])O1
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])N=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(=NC2=C(C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C3=C2N([H])C(=S)N3[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)C([H])=C(C2=C1C([H])=C1OC([H])([H])[C@]([H])(N(C1=C2[H])C([H])([H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=NC([H])=C(C([H])=C1[H])[C@]([H])(C(=O)N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C([H])C(C#N)=C([H])C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(C2=C([H])C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])S1)C([H])([H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C(=O)C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C4=C3C([H])=C([H])O4)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=NN2[C@@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C2=C([H])N=C([H])C([H])=C2[H])=C1C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])C4=C(C5=C(N4[H])C([H])=C([H])C(=C5[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]C1=C([H])C([H])=C(O1)C([H])([H])N1C(SC([H])([H])C2=C([H])C(=C([H])C3=C2OC([H])([H])OC3([H])[H])C(=O)OC([H])([H])C([H])([H])[H])=NC2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]C1=C([H])C([H])=C(O1)C([H])([H])N1C(=O)C2=C(SC3=C([H])C([H])=C([H])C([H])=C3C2=O)N=C1C([H])([H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])S[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])C([H])([H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])O[H]
[H]OC1=C(\C([H])=C(/[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])[C@]2(C([H])([H])[H])[C@@]([H])(N(C1=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]4(OC([H])([H])C([H])([H])C4([H])[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2[H])C#N)N1C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])N(N=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC(C2=C([H])C([H])=C(O2)C([H])([H])[H])=C(C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C1=NC([H])=C([H])C(=C1[H])C1=C(N=C(S1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C(O[H])C([H])=C2OC(=C(C3=C([H])N(N=N3)C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C3=C4C([H])=C([H])C([H])=C([H])C4=C([H])C([H])=C3[H])C2=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])N([H])C(=O)C1=NO[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C2=C([H])C([H])=C([H])C([H])=N2)C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN([H])C2=C1C(=NC([H])=N2)N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C2=C([H])C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])N(C(=N2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N([H])S(=O)(=O)C([H])([H])[H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=NS2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NN1[H]
[H]OC(=O)C1=C([H])C([H])=C(C(N([H])C2=C([H])C(=O)N(C3=C2C([H])=NN3C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(N([H])C(=O)N([H])C1=O)C([H])([H])N1C(=O)C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)C(=O)OC1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C(=O)C([H])([H])[H]
[H]O[C@@](C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])C([H])([H])C1([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C(F)(F)C1([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C([H])C2=C1OC([H])([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1[H])C1=NC(=C(C(=O)OC([H])([H])C([H])([H])C([H])([H])[H])C(=C1C(=O)OC([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C(N=C([H])C([H])=C1[H])C(=O)N([H])C1=NN=C(S[H])S1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C(=C1[H])C1=NN=C(O1)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]O[C@@]1([H])[C@]([H])(O[H])[C@@]([H])(C([H])([H])[H])C([H])([H])[C@@]1([H])N1C([H])=NC2=C1N=C([H])N=C2N([H])[H]
[H]N1C(=O)C([H])=C(C2=C([H])C([H])=C(F)C(F)=C12)C([H])([H])N1C2=NC([H])=C([H])C(N(C([H])([H])[H])C([H])([H])[H])=C2N=C1C1([H])C([H])([H])C([H])([H])C1([H])[H]
FC1=C(C=C(CC2=NNC(=O)C3=C2C=CC=C3)C=C1)C(=O)N1CCC2=C3C1CNC(=O)C3=CC=C2
[H]OC1=C(\C([H])=C(/[H])C([H])([H])[C@]2([H])C(=C([H])[H])C([H])=C(C([H])([H])[H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])=C(OC([H])([H])[H])C(Br)=C1[H]
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])N1C([H])=NC2=C(C1=O)C(N([H])C1=C([H])C([H])=C(I)C([H])=C1F)=C([H])C(=O)N2C([H])([H])[H]
[H]C1=C(C2=C([H])C([H])=C([H])C([H])=C2N1S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[C@@]([H])(OC([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=NC([H])=NC(N2C([H])([H])C([H])([H])N(C(=O)N([H])C3=C([H])N=C(OC4([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])=C1\C([H])=N\OC([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C2=C([H])C(OC3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])C(F)=C1[H]
[H]O[C@]([H])(C([H])([H])[H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]N1C(=NC2=C1C([H])=C(Cl)C(Cl)=C2[H])[C@@]1([H])N(C2=NC([H])=NC(=C2[H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C3=C(C([H])=C([H])C([H])=C3[H])N(C1=O)C([H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NN=C2C([H])=C([H])C(=NN12)C1=C([H])SC([H])=C1[H]
[H]N([H])C1=NC([H])=C2C([H])=C(C(=NC2=C1[H])N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])(C(=O)O[H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])SC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C(N([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[H]
OC1=C2C(=O)C=C(OC2=CC(OCCCCCCON(O)=O)=C1)C1=CC=CC=C1
[H]N(N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C([H])C2=C1C(=O)C1=C(N([H])N=C21)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C3C(N([H])C([H])=C3C([H])([H])C([H])([H])C1([H])[H])=C([H])C([H])=C2[H]
CNC1=NC(NC2=C(Cl)N(C)N=C2)=NC=C1C(F)(F)F
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])N(C(=O)N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C(C#N)=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]S\C(=N/C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
CC1=CC2=C(OC=C3CN(CC4=CC=C(C=C4)S(N)(=O)=O)[Zn]4(Cl)(Cl)(OC5C(CN4CC4=CC=C(C=C4)S(N)(=O)=O)=COC4=CC=C(C)C=C54)OC23)C=C1
[H]C1=C([H])C(Cl)=C([H])C2=C1C(=NO2)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])C3(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2=O)C([H])([H])C1([H])[H]
[H]C1=NN(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C2(C1([H])[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C(C#N)=C2[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])N3C([H])=C([H])N=C23)C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])N=C([H])C([H])=N3)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C3=NC([H])=NC(N([H])C4=NN([H])C(=C4[H])C([H])([H])C(=O)N([H])C4=C(F)C(F)=C([H])C([H])=C4[H])=C3C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C1=NN(C(OC([H])([H])C([H])([H])C2=NC3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N3[H])=C1[H])C([H])([H])C(F)(F)F
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C(C2=C(N=C([H])N=C2N2C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])N1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C2=C(C([H])=N1)C(=NC([H])=N2)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Br
[H]N(C(=O)C1=C(N([H])C(=O)C2=C(Cl)C(=C([H])S2)C([H])([H])N([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C([H])C(Cl)=C1[H])C1=NC([H])=C(Cl)C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[N+]([O-])=O)S(=O)(=O)N([H])C1=NC([H])=NC2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=S)N(C(=O)C2=C1C([H])=C(C([H])=C2[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(OC(=O)C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1=NN=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=O)C([H])=C(C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C(O[H])C(F)=C1[H]
[H]N(C(=O)C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(SC([H])([H])[H])C([H])([H])[H])[C@]([H])(C2([H])[H])[C@@]1([H])C([H])([H])[H]
[H]N(C1=NC(N([H])C2=C(C([H])=C([H])C([H])=C2[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=N1)C1=C([H])C2=C(C([H])=C1OC([H])([H])[H])N(C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[C@]2([H])OC([H])([H])C([H])([H])C2([H])[H])N2N=C([H])C(=C2[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
CN1C(=O)N(C2CCN(CC2)C(C)=O)C2=C1C=NC1=CC=C(N=C21)C1=CC=C(C)N=C1
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(Br)=C([H])C([H])=C2OC([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])[C@@]2(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]S[C@@]([H])(C([H])([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])=C3N(C4=C(C([H])=C([H])C([H])=C4[H])C3=C2[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]2([H])F)C([H])([H])C1([H])[H]
CO[C@H](C[C@H](CCN(C)C)C(=O)NO)C1=CC=C(F)C=C1
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(OC2=C(N([H])S(=O)(=O)C3=C(Cl)C([H])=C(Cl)C([H])=C3[H])C([H])=C(C([H])=C2[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(C#N)=C1[H]
[H]OC1=C([H])C(=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C(O[H])C([H])=C2C([H])([H])[H])[C@]2([H])[S@@](=O)[C@@]1([H])C([H])([H])[C@]2([H])S(=O)(=O)OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1[C@@]2([H])C([H])([H])[C@]1([H])C([H])([H])N(C1=C([H])N=C([H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])C(=NN1[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=NC2=C([H])C([H])=C(Cl)C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]OC1=C(Cl)C([H])=C(\C([H])=C2/S\C(=N/C([H])(C([H])([H])[H])C([H])([H])[H])N(C2=O)C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C([H])([H])N1N=C(C(=C1C([H])([H])[H])C([H])([H])N(C([H])([H])C1=NC(=NO1)C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2C(N(C(=O)C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1OC([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1(OC([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C(\[H])=C1\C2=C(C([H])=C([H])C([H])=C2[H])N(C(=O)C2=C(Cl)C([H])=C(C([H])=C2[H])N2N=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C([H])N2C(=NN=C2C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=C1[H])C([H])([H])OC([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC([H])([H])C([H])([H])OC1=C([H])C2=C(N([H])C3=C(C(=O)N([H])[H])C(=NN3C([H])([H])C2([H])[H])C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)[C@]1([H])[C@@]([H])(SC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C(=O)N=C2C([H])=C([H])C([H])=C([H])N2C1=O
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]O[C@@]1(C#CC([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])[C@@]3([H])C(=C4C(=C([H])C(=O)C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])[C@@]([H])(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])Br)C([H])=C3[H])C([H])([H])[C@]12C([H])([H])[H]
[H]OC(=O)C1=C(C(=NC2=C([H])C([H])=C(F)C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=NC2=C(C(=NN2C(=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])C([H])(N([H])C(=O)C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])O[H]
[H]C1=C([H])C([H])=C2C(=O)N(C3=C([H])C([H])=C(Cl)C([H])=C3[H])[C@@]([H])(C2=N1)C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1O[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C([H])S2)C2=NOC(=N2)C2=C([H])C([H])=C(OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])N(C(SC([H])([H])C(=O)N2C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])C2([H])[H])=N1)C1=C([H])C([H])=C([H])C(=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C(OC([H])([H])C(=O)OC([H])([H])[H])=C(C([H])=C1Cl)C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C([H])C(=C1N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=NC([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N([H])C1=NC([H])=NC(OC2=C([H])C(Cl)=C(N([H])C(=O)N([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])=C1\C([H])=N\OC([H])([H])[H]
[H]OC1=C([H])C(\C([H])=C(/[H])N([H])C([H])=O)=C(O[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]([H])(N([H])C1=C(C([H])=NC([H])=C1[H])S(=O)(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])F)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2N=NC([H])=C2[H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC([H])([H])C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1(OC([H])([H])[H])C(=O)N2C(C(=O)OC([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C(C([H])([H])SC3=NN=NN3C([H])([H])[H])C([H])([H])O[C@]12[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]21[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(C(=O)C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(=N2)C([H])([H])N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])S1)C1=C2C([H])=C([H])N([H])C2=C([H])C([H])=C1[H]
[H]O\N=C(\C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C([H])([H])[H])C([H])([H])C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C1[H])N1C(=NC(=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N2C1=C(Cl)C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C(Cl)C(=N1)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])N12)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1([H])N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])([H])SC([H])([H])C([H])([H])C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C1=O)C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OP(=O)(O[H])O[H])C([H])=C1[H]
CN(C)CCCNC(=O)C1=C(C)N(C(=C1)C1=CC=CC=C1)C1=CC=C(C=C1)S(N)(=O)=O
FC1=CC=CC=C1\C=C1/CNC\C(=C/C2=C(F)C=CC=C2)C1=O
[H]N(C1=NC([H])=C([H])C2=C1C(=NC2([H])[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)N1C2=NC([H])=C([H])C([H])=C2N([H])C(=O)C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C([H])([H])SC([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])S1
[H]N1C(=O)C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]OC1=C2C(=NN(C2=C2C([H])=C(C([H])=C([H])C2=N1)[N+]([O-])=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C([H])C2=C1[H]
[H]N([H])S(=O)(=O)C1=NN(\C(S1)=N\C([H])([H])C1=C([H])C(=O)OC2=C1C([H])=C([H])C(Cl)=C2[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1N=C([H])C(Cl)=C(Cl)C1=O)[C@]1([H])C([H])([H])C([H])([H])S(=O)(=O)C1([H])[H]
[H]N([H])C1=NOC2=C([H])C([H])=C(C([H])=C12)N1N=C(C([H])=C1C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C(=O)C1=C([H])N=C(C([H])=N1)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=NC(Cl)=C1SC1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C2C(=O)C3=C4C(C([H])=C([H])N=C4C2=C1[H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=NC2=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N2[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1O[C@@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])S1)S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N(C(=O)C2=C([H])C([H])=C(Br)C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=NC2=C(N1[H])C(=C([H])C([H])=C2[H])C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=O)N(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C4([H])[H])C([H])=C3[H])C(=NC2=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@]1([H])C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[H])C1=O
[H]OC1=C([H])C([H])=C2N([H])C3=C(C([H])=C([H])[N+](=C3[H])C([H])([H])[H])C2=C1[H]
[H]OC(=O)C([H])([H])N1C2=C([H])C([H])=C(F)C([H])=C2C(=C1C([H])([H])[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C(OC1=O)C1=C(C([H])=C(OC([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])=C1[H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1OC([H])([H])[H])[C@@]13C([H])([H])C4=C(C5=C(N4[H])C([H])=C([H])C([H])=C5[H])C([H])([H])[C@@]1(O[H])[C@]([H])(N(C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C3([H])[H])C2([H])[H]
[H]C([H])=C([H])C1=NN2C(SC(=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=N1
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C(=O)N(C1=C(SC([H])([H])[H])C(=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])OC1=C2N=C(C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NC(SC2=NN=C([H])N2C([H])([H])[H])=C([H])C([H])=C1SC1=C([H])C([H])=C(F)C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C(OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C(C([H])=C1C(F)(F)F)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(N([H])C1=C(C#N)C(N([H])[H])=C([H])C(=N1)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(N([H])S(=O)(=O)C2=C(\C([H])=C(\[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(SC3=C([H])C([H])=C(Cl)C([H])=C3[H])C3=C(C([H])=C([H])N=C3N2C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N1C(=O)C2=C(SN=C2C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N=C1C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(\C([H])=C(/[H])C2=C(Cl)C([H])=C(OC([H])([H])C3=C(ON=C3C([H])([H])O[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])=C1[H]
[H]N1C(=O)C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])=C(C3=C([H])C([H])=C(C#N)C([H])=C3[H])C([H])([H])C1([H])[H])C(Cl)=C([H])C([H])=C2[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])N2C(=C1[H])C(=O)N(C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[Cl-].[H][C@@]12C[C@@H]3C[C@@H](C3(C)C)[C@]1(C)OB(O2)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)C1=CC(CC2=CC=CC=C2C)=CC=C1
[H]N(C1=NC2=C(S1)C([H])([H])C([H])([H])C([H])([H])C1=NN([H])C([H])=C21)C1=NC(OC([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])C([H])([H])C([H])([H])N2[H])=C([H])C(O[H])=C1[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1O[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=C([H])N=C1C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]C1=C(N=C(S1)C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N1N=C(C2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])N(C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])C2([H])[H])S1(=O)=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C2=C([H])C(=O)C([H])([H])C([H])([H])[C@]2(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(N([H])C([H])([H])P(=O)(O[H])O[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C(=O)C1=C([H])C([H])=C2N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]OC1=NSC(N([H])C2=C([H])C([H])=C(I)C([H])=C2[H])=C1\C(=N\C([H])(C([H])([H])[H])C([H])([H])[H])N([H])[H]
[H]N(C(=O)[C@@]([H])(N1C(=O)[C@@]([H])(N(C(=O)[C@]([H])(N([H])C(=O)C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])[C@@]1([H])SC2=C(C([H])=C(F)C([H])=C2[H])[C@@]1([H])OC([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1F
[H]N1C([H])([H])[C@]2([H])C([H])([H])[C@]2(C2=C([H])C3=C(S2)C([H])=C([H])C([H])=C3[H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@](N([H])C(=O)[C@@]1([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C(=NC([H])=N1)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C(Br)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])[C@]([H])(N([H])[H])C([H])([H])C2=C(F)C([H])=C([H])C(F)=C2[H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])[C@]4([H])[C@]5(C([H])([H])[C@@]35C(=O)C([H])([H])[C@]2(C([H])([H])[H])[C@@]1([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])N=C(SC([H])([H])[C@@]41C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]1([H])C2=C(OC([H])([H])C1([H])[H])C([H])=C([H])C([H])=C2[H]
[H]OC1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])C1=C([H])C(O[H])=C(O[H])C(O[H])=C1[H]
[H]OC1=C2O[C@@]3([H])C4=C(C([H])=C(C([H])=N4)C4=C([H])C([H])=C(Cl)C([H])=C4[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C1=C(C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C(OC([H])([H])[H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O)[C@@]([H])(C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]\C(C1=C([H])C([H])=C(OC(=O)C([H])([H])[H])C([H])=C1[H])=C1/C(=NC([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
OC(=O)C1=CC(OCC2CCN(CC2)C2=NC=C(NC(=O)C3=CC=C(OCC4=CC=CC=C4)C=C3)C=C2)=CC=C1
[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N1C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(N(N=C1C([H])([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(F)C([H])=C2F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])N(C2=C3C(Cl)=C([H])N([H])C3=NC([H])=N2)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=NN1C1=C([H])C([H])=C2C([H])=C(Cl)C([H])=C([H])C2=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C(=S)C(C(=O)C([H])([H])[H])=C(SC([H])([H])[H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N1N=C(C([H])=C([H])C1=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N=C2C([H])=C([H])C([H])=C(N12)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])S(=O)(=O)C2=C([H])C3=C([H])C([H])=C(Cl)C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C(=O)N(C(=N2)C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(OC2=C(N([H])C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3S(=O)(=O)N([H])[H])C([H])=C(Br)C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C([H])C(F)=C(C([H])=C2[H])C2=NC3=C([H])C(=C([H])C([H])=C3S2)[C@@]([H])(C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])[P@@](=O)(O[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])SSC([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])O[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(O1)C([H])([H])[H])C1=NC([H])=C([H])S1
[H]N(C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])N([H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C([H])=C2C([H])=C([H])C(=NC2=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1(C2=C([H])C([H])=C(OC([H])([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])C([H])=C2[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1=C([H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
FC1=CC=C(C(=O)N2CCN(CC2)C2=NN=C(C=C2)C(=O)NCCC2CC2)C(=C1)C(F)(F)F
[H]N(OC([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C(=N1)N(C([H])=C(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=NN=C(O1)SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C(=O)N([H])C(=C(C(=O)OC([H])([H])[H])[C@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])OC([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3C#N)C([H])([H])C2([H])[H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C3=C(SC2=C1[H])C([H])=C([H])C(=C3[H])C(F)(F)F)C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])N2[C@]1([H])[C@]([H])(N(C1=C(C(Cl)=C(C#N)C([H])=C1[H])C([H])([H])[H])S2(=O)=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N(\N=C(/[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=NOC3=C2C([H])=C([H])C2=C(F)C(O[H])=C([H])C([H])=C32)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C(=C([H])C([H])=N1)C1=C([H])C2=C(N1[H])C([H])([H])C([H])([H])N([H])C2=O
[H]N1C(=NC2=C([H])C([H])=C([H])C([H])=C2C1=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])N1C(=O)C(=O)N(C2=C([H])C([H])=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1(O[H])C([H])([H])[C@@]([H])(OC1(C([H])([H])[H])C([H])([H])[H])N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C1=C(C3=C(N1[H])C([H])=C([H])C([H])=C3[H])C1=C2C(=O)N([H])C1([H])[H]
CN1N=C(C)C(C(=O)N2CCCCC2C2=CC=CN=C2)=C1OC1=CC=CC=C1C#N
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])[C@@]12C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N(C1=NC3=C(N1[H])C([H])=C(F)C(F)=C3[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(Cl)=C([H])C([H])=C1N([H])C1=C(N([H])C2=C(Br)C([H])=C([H])C([H])=C2[H])C(=O)C1=O
[H]N1C(=O)C2=C(C1=O)C1=C(N(C3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C1=C2C2=C(N1[H])C([H])=C(F)C([H])=C2[H]
[H]N(C(=O)C1=C([H])C([H])=C(\N=C(/N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N2C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1C(=O)C2=C(C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H]
[H]OC1=C([H])\C(=N\C2=C3C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C3=NC([H])=N2)C(=O)C([H])=C1Br
[H]N1C2=NC3=C(N2C([H])=C1C1([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N3C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=NC(=C([H])N2N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@](C2=C(F)C([H])=C([H])C(F)=C2[H])(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]C1=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C(Br)C(=C1[H])C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C(=O)N(C(=O)C1([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N([C@]1([H])C(=O)N(C([H])([H])C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C([H])C(Cl)=C2[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(O[H])C(Br)=C([H])C([H])=C1[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])[C@@]1([H])C2=NN(C(=C2OC([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC(=O)C([H])([H])N1C(SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])C1=C(Cl)C([H])=C(C(=O)OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC3=C(N=C([H])N3C([H])(C([H])([H])[H])C([H])([H])[H])C(=N2)N([H])C([H])([H])C2=C([H])C([H])=C(S2)C2=C([H])SC([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])[C@]([H])(C(=N\OC([H])([H])C([H])([H])C([H])([H])SC([H])([H])[H])\C([H])([H])N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])N1N(C(=O)C(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1(C(=O)N([H])C(=O)N([H])C1=O)C([H])([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
COC1=CC=C2C=C(CNCCC3=CC(Br)=CC=C3)C(=NC2=C1)C1=CSC=C1
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=NC([H])=C2[H])C1=O)C([H])([H])[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C(F)(F)F
[H]N1C2=C([H])C([H])=C(C([H])=C2C(C(=O)C1(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])SC(C#N)=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=O)C2=C(N=C(S2)C([H])([H])[H])C1=O
[H]N(C1=C(C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC2=C1N([H])C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=NC(=NC2=C1N=C(N([H])C([H])([H])C1=C([H])C([H])=C([H])S1)C2([H])[H])N([H])[H]
[H]N([H])C(C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C2=NN(C(=O)[C@@]2(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(C([H])=C2[H])N2C(=NO[C@]2([H])C2=C([H])C([H])=NC([H])=C2[H])C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C1=NC2=C(OC([H])([H])[H])C([H])=C([H])C(N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])=C2S1
[H]O[C@]([H])(C([H])([H])N1N=C(C2=C1C([H])([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(C#CC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C(Cl)C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N(N=N1)[C@@]1([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@]1([H])OC(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C1=NN=C(S1)C1=C([H])C([H])=C([H])S1
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1O[H])C([H])([H])C([H])([H])C1=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N1C(=O)N(C2=C(C([H])=NC([H])=C2[H])C1=O)C([H])([H])C1=C([H])N(C2=C1C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C2=C([H])C(\C([H])=N\N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]OC(=O)[C@@]1([H])[C@@]([H])(N(C([H])([H])C(=O)N([H])C2=C(C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N1C(=O)C([H])([H])N(C(=O)[C@]([H])(C([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC2=C([H])C([H])=C(Cl)C([H])=C2C1=O
[H]OC1=C([H])C2=C(OC([H])([H])[C@]([H])(O2)[C@@]2([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])N=C([H])C(=C1[H])C1=C([H])N=C(N=N1)N1C([H])([H])C([H])([H])C([H])(OC2=C(Br)C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C(=O)C2=C([H])N=C3C([H])=C([H])C([H])=C([H])C3=N2)C(=O)[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])N1C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C1=C([H])N(N=N1)C([H])([H])C(=O)N(C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C(=O)\C(=C2/N([H])C3=C(C([H])=C([H])C([H])=C3[H])/C/2=N\OC([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)O[H])C([H])([H])P(=O)(O[H])O[H]
[H]OC1=NC(=NC2=C1C([H])=C([H])C([H])=C2[H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=N1)C(=O)N([H])C([H])([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])[C@]([H])(C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N([H])C(=O)C1=C2N([H])C3=C(C([H])=C(F)C([H])=C3[H])C2=C(N=C1[H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C(\[H])=C(/[H])C1=C(C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(C3=C(O2)C([H])=C([H])C([H])=C3OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C1/C(=O)N([H])C2=C1C(Br)=C([H])C(=C2[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])C1=C([H])C2=C(OC([H])=C2[H])C([H])=C1[H]
[H]O[C@@]([H])([C@@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])N(C(=O)C1([H])[H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H])[C@]1([H])N([H])C([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])(C(F)(F)F)C(F)(F)F
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@](N(C1=C([H])C([H])=C([H])C(=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])(C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C2N=C(N=C2N(C(=N1)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])O1)N([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N=C([H])C(=N1)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C2C(=NN([H])C2=C1[H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C3N(C(=O)[C@]([H])(N4C([H])([H])C([H])([H])N(C([H])([H])C5=C([H])C([H])=C(Cl)C([H])=C5[H])C([H])([H])C4([H])[H])C([H])([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C3=C1[H]
[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NN2C(=O)C3=C(SC(=C3C([H])([H])[H])C([H])([H])[H])N=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]OC(=O)C([H])([H])C([H])([H])C(=O)OC1=C(C([H])=C(SC(SC2=C([H])C(=C(O[H])C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N([H])C1=C2C(=O)C3=C(N([H])N=C3C2=C([H])C([H])=C1[H])C1=C(N=C(S1)C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C1=NC(=C([H])N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])SC1=C([H])C([H])=C2C3=C(C(=O)OC([H])([H])C(=O)OC([H])([H])C(F)(F)C(F)(F)F)C(=O)N=C3C3=C2C1=C([H])C([H])=C3[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])O[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])[C@]([H])(OC([H])([H])C4=C([H])C([H])=C(N=C=S)C([H])=C4[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]N(C(=O)C#CC([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=NC([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]N(C1=NC(=C([H])S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C(O[H])C([H])=C2OC1([H])[H]
[H]\C(=C(\[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N1C(=O)S[C@@]([H])(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC2=C(C([H])=C(OC3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]OC(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C(\[H])=C(/[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(SC2=NN3C([H])=C([H])C([H])=C3C(=N2)N([H])C2=NN([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C(C(C#N)=C(N1C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])OC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]N(C1=NC(Cl)=C(SC([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C1=C(C(=O)OC([H])([H])[H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])[C@@]([H])(OC([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=NC3=C2[H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C1=NC(SC([H])([H])C2=C(F)C(F)=C([H])C([H])=C2[H])=NC2=C1N=C(C(=O)OC([H])([H])[H])C(=O)N2[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
CC(CCOC1=CC2=C(C=CC(=O)O2)C=C1)C1=CC(=O)C(C)(C)O1
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C(N([H])C2=C(N([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C(=O)C2=O)=C([H])C([H])=N1
[H]OC([H])([H])C([H])([H])OC1=C([H])C2=C(N=C(S2)S(=O)(=O)N([H])C(=O)C([H])([H])N([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C(Cl)C2=C(S1)C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N2N=C(C3=C([H])N=C(N=C23)N([H])C([H])([H])C([H])([H])OC([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C#CC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])[C@]2([H])N([H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC([H])=C3N=C(N([H])C4=C(F)C([H])=C(F)C([H])=C4F)N(C3=N2)[C@@]2([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])[H]
[H]N([H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])N1C(=C([H])C([H])=C1C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N([H])C2=C([H])N=C([H])N=C2[H])C([H])=C1[H]
[H]OC1=C([H])C(\C([H])=C(/[H])C(=O)C2=C([H])C(=C([H])C([H])=C2[H])C2=C([H])C(F)=C([H])C([H])=C2[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C([H])([H])N1C2=C([H])C(=O)C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])[H])[C@@]1(O[H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])[C@]4([H])N(C(=O)C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])C([H])([H])C2=C([H])C(I)=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])N([H])C(=O)N([H])[H]
[H]N(C(=O)N1C(=O)N([H])C(=C(C(=O)OC([H])([H])[H])[C@@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(C#N)(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(N1C(=O)[C@@](C2=C([H])C([H])=C(OC([H])([H])C([H])=C([H])[H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C(Cl)=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)S1
[H]N1C([H])=NC(=C1[H])C([H])([H])N1C2=C(C([H])=C(Br)C([H])=C2[H])C([H])([H])N([C@]([H])(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C1=C(C#N)C([H])=NC2=C1C([H])=C(S2)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C2=C(N([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)\N=C1\SC(=NN1C([H])([H])[H])S(=O)(=O)N([H])[H]
[H]OC1=NC(=NC2=C1C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])N(C1=C([H])C(F)=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])C#C[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])N1C2=C([H])C([H])=C(C([H])=C2C2=C1C([H])([H])C([H])([H])N(C2([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=NC(=C(C(=O)OC([H])([H])[H])[C@]2([H])C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=NC([H])=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(F)=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N([H])[C@@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C([H])C([H])=C(C([H])=C12)C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N(C([H])([H])[H])[C@@]1([H])C2=C([H])C(F)=C([H])C([H])=C2[C@@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N1C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C1=NOC(=N1)C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N2C([H])=C([H])N=C2C(=N1)N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])C([H])([H])C1=C([H])C([H])=C(N=[N+]=[N-])C([H])=C1[H]
[H]N([H])C(=O)[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@@]([H])(N([H])C(=O)[C@]1([H])SC([H])([H])C([H])([H])N1S(=O)(=O)C1=C([H])C(F)=C([H])C([H])=C1[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]N(C1=C([H])C([H])=C2C(=C1[H])N(C([H])=C2C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C2=NC(N([H])C3=C(C([H])=C([H])C([H])=C3[H])C(=O)O[H])=C([H])C([H])=N2)C([H])=C1[H]
[H]N(\C(=N/C#N)N([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(Cl)(Cl)C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1OC([H])([H])[H]
[H]N1C(=O)C2=C(N=C1C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(=NN2C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C2=NN=C(O2)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])N1C(=O)N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H][C@]12CC[C@]([H])(C[C@H](C1)OC1=CC=CC(=C1)C(N)=O)N2C1CCCC2=C1C=CC=C2
[H]C1=C([H])N(C([H])=N1)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2N(C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=NC(=S)C2=C1N(C([H])=N2)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(OP([O-])(=O)OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]1=C(\C([H])=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C2\N(C3=C(C4=C([H])C(=C([H])C(=C4C([H])=C3[H])S(=O)(=O)O[H])S(=O)(=O)O[H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(C2=C3C([H])=C(C([H])=C(C3=C([H])C([H])=C12)S(=O)(=O)O[H])S(=O)(=O)O[H])(C([H])([H])[H])C([H])([H])[H])C(=O)O[H])C(=O)O[H])C(=O)O[H]
[H]N([H])C(=O)C1=C2C(OC([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])=C([H])C4=C3C([H])=C([H])C([H])=C4F)C2([H])[H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C(OC([H])([H])[H])=C([H])C2=C1C(=O)C(O[H])=C(O2)C1=C([H])C(O[H])=C(O[H])C([H])=C1[H]
[H]N1C(=O)C(=C(OC(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1C([H])([H])[H])[N+]([O-])=O
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=N3)C([H])=C12
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1C(=O)C(C1=O)(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@]([H])(N([H])C1=C3N=C([H])N(C3=NC([H])=N1)[C@]1([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]1([H])O[H])C([H])([H])C2([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2N(C(=N3)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)C2=C([H])C(=C([H])C(=C2[H])C(=O)N([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])OC([H])([H])C2=C([H])C(F)=C([H])C(F)=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C(=O)O[H]
[H]O[C@](C#CC1=NC(N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C2N=C([H])N(C2=N1)C([H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=NC(=C([H])C([H])=N1)C1=C(N=C([H])N1C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(S1)C([H])=C(C([H])=C2[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C([H])O2)C([H])([H])C1([H])[H]
[H]SC(=N[H])N([H])\N=C(/[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC([H])([H])[C@@]1([H])C([H])([H])[C@@]([H])(OC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(N([H])C(=O)N([H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(C#N)=C([H])C([H])=C1C1=C([H])C([H])=C2N([H])C(=O)C([H])([H])O[C@](C3=C([H])SC([H])=C3[H])(C2=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S1(=O)=O)[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])C(OC3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C12)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1Cl
[H]N(C(=O)C1=C(C([H])=C(N([H])C([H])([H])C2=C([H])N=C([H])N2C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(Cl)=C2[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)C([H])([H])[H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=NC2=C(S1)C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])=C(C2=C([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])[C@]([H])(O[H])[C@@]2(C(=O)N([H])C([H])([H])[H])C([H])([H])[C@]2([H])[C@@]1([H])N1C([H])=NC2=C1N=C(N=C2N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C#CC([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]N(C1=NC([H])=C(Cl)C(=N1)N([H])C1=C(F)C([H])=C([H])C([H])=C1C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C2N(C(=O)C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])OC2=C1[H]
[H]C1=NN(C([H])=N1)[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2O[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C(C2=C1C(=O)C([H])=C(O2)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=NN1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)C([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C2N(C3=C(C2=C1[H])[C@@]1([H])N([H])[C@]([H])(C([H])([H])C1([H])[H])C3([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C([H])=C(N([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])=C([H])C2=N1
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(OC1=C(C([H])=C2N(C(=O)OC2=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(C([H])=C(C([H])=N1)C1=C([H])N(N=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC2=C(O1)C([H])=C(F)C([H])=C2[H]
[H]ON([H])C(=O)C1=C([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C34)C([H])=C2S1
[H]N(C1=C(N=C([H])C(=C1[H])C([H])([H])[H])C1=C2N=C(C([H])=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N2N=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(Cl)=C(C([H])=C1[H])C1=NN(N=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C(=O)C2=C1C([H])=C(\C([H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(F)=C1N([H])C1=C(Cl)C([H])=NC(=N1)N([H])C1=C([H])C([H])=C2N(C(=O)C([H])([H])C([H])([H])C(C2=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(N=O)C(O[H])=C2C([H])=C(F)C(Cl)=C(F)C2=N1
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C(C#N)C([H])=N1)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])[C@]2([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[N@+]2(C([H])([H])[H])C([H])([H])Cl
[H]N1N(C(=O)C2=C(N(C(=C2C1=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])=C1[H])C(=O)N([H])C1=C([H])N(N=C1C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C(=C1F)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]C1=C([H])C([H])=C2C(SN=C2C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C1[H]
[H]OC(=O)C([H])([H])C1=C(N(C(=O)C2=C(C([H])=C(OC([H])([H])C3([H])OC4=C(O3)C([H])=C([H])C([H])=C4[H])C([H])=C2[H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(SC2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=N3)=C([H])C([H])=C2[H])C(=C1C(F)(F)F)C(F)(F)F)C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])[C@@]2([H])N(C(=O)[C@@]([H])(N([H])S(=O)(=O)C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]3([H])C([H])([H])C1=C2C(OC(=O)C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C1=C([H])C(C(=O)N([H])C2=C([H])N=C([H])C([H])=C2[H])=C(Cl)C([H])=C1[H]
[H]N1C(=O)[C@]2(N(C(=O)[C@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C(F)C([H])=C3[H])=C1[H])C([H])([H])C2([H])[H]
[H]\C(=C(\[H])[N+]([O-])=O)C1=C([H])C2=C(C([H])=C1[H])N(C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=N[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=NOC(=C1[H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2(N3C([H])=C([H])C(=O)N([H])C3=O)C([H])([H])[C@@]2([H])[C@]1([H])C([H])([H])O[P@](=O)(O[H])OP(=O)(O[H])O[H]
[H]OC1=C2C([H])=C([H])C([H])=C([H])C2=C2N([H])C(=C(C(=O)OC([H])([H])C([H])([H])[H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2[H])C2=NC3=NC([H])=NC(N([H])[H])=C3C(=C2[H])C2=C([H])C(Br)=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])O[H]
[H]C1=C(Cl)C([H])=C(C2=NC(=C3N=NC4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C4N23)C([H])([H])[H])C(Cl)=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C(\N=C(/N([H])C#N)N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C(=S)N([H])N([H])C(\[H])=C1/C(=O)C(OC2=C1C1=C(C([H])=C([H])C(=O)O1)C([H])=C2[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=NS2)N1C([H])([H])C([H])([H])N(C([H])([H])C#CC([H])([H])N2C(=O)C3=C([H])C([H])=C([H])C([H])=C3C2([H])[H])C([H])([H])C1([H])[H]
COC1=CC=C(NC(=O)C2=C3C=CC=CC3=C(CN3C=CN=N3)C=C2)C(=N1)C(=O)NCC1CCC1
[H]N([H])C1=C([H])C(=NC2=C([H])C([H])=C(N([H])C(=O)C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])=C12)C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C2C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]ON([H])C(=O)C1(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3F)C([H])=C2[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C([H])C(C#CC3=C([H])C([H])=C([H])C([H])=C3[H])=C(OC([H])([H])[H])C([H])=C12
[H]N(C(=O)O[C@]1([H])C([H])([H])C([H])([H])[C@@]2(OC2([H])[H])[C@]([H])([C@]1([H])OC([H])([H])[H])[C@]1(O[C@]1([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])Cl
[H]N(C(=O)N([H])C1=C(C(=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=C2C([H])=C([H])C([H])=C(OC([H])([H])C(F)(F)F)N2N=C1C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@]1(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C(=O)N([H])C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2C([H])([H])N([H])[H])C2=C(C([H])=C([H])N=C2[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C(SC2=C([H])C([H])=C(F)C([H])=C2F)=C([H])N2C1=NN=C2C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])OC(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(C#CC([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1Cl)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC1=C([H])C([H])=C2C(=O)N(SC2=C1[H])C([H])([H])[H]
[H]OC1=C(C([H])=C2O[C@@]([H])(C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[C@@]([H])(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(N=C1O[C@@]([H])(C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[C@]([H])(O[H])C([H])([H])O[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])[H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)[C@@]([H])(O[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])O[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)[C@]([H])(O[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C(=C([H])C([H])=C12)N1C([H])=NN=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2OC1=O
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(O1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C([H])C(=C([H])C([H])=C2N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]2([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1Cl)C1=NN=C(N1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N1C(=O)C([H])([H])OC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])[N+]([O-])=O
[H]N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2[C@@]1([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=N1)S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
CN(C)CCC(=O)NC1=NNC2=NN=C(C=C12)C1=CC=CC=C1
[H]N(C(=O)C([H])([H])[H])C1=C(N(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])S(=O)(=O)C2([H])[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]C1=C([H])N(C([H])=N1)C([H])([H])C([H])([H])OC1=C([H])C(=O)OC2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])C4=C([H])C([H])=C([H])C([H])=C4N3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)C(=O)N([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])C3=C(N=C(N([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])N3[H])C([H])=C12
[H]C1=C([H])C(=O)N2C(=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])[C@@]([H])(C2([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@]([H])(N1C([H])=NC([H])=C1[H])C([H])([H])[C@]([H])(O2)C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=CC=C(OC2=C(Cl)C=NN(CC3=CC=C(F)C4=CC=CC=C34)C2=O)C=C1
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=NC(C2=NN=C(O2)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C(=NN1C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC([H])=C([H])S1
[H]OC(=O)[C@@]1(F)[C@]2([H])C([H])([H])[C@@]([H])(OC([H])([H])C3=C(F)C([H])=C(F)C([H])=C3[H])[C@@](N([H])[H])(C(=O)O[H])[C@]12[H]
[H]OC([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C2C(=N1)C([H])=C([H])C([H])=C2N([H])C(=O)C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(=C2[H])C(=O)C([H])([H])SC(=S)SC([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N1N=C([H])C2=C1C([H])=C([H])C1=C2C([H])([H])[C@]2(C1=C(Br)C(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)N([C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON(C(=O)N([H])[H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])N(C(=O)O[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]C1=NC([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C2=C(C#N)C(=O)N(C([H])=C2[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])N(C3=C([H])N=C(Cl)C(=C3[H])C([H])([H])[H])[C@@]2([H])C1([H])[H]
[H]N([H])C(=NC1=NC([H])=C(Cl)C([H])=C1\C([H])=C(/[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]N1C2=C([H])C([H])=C(Cl)C([H])=C2C(=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(N([H])C(=N[H])N([H])[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]1([H])N([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(=C([H])S1)C(=O)C([H])([H])[H]
[H]N1C(=S)N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=NC2=C([H])C3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C(=O)N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C([H])=C3N([H])C2=N1
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])N(C1=C([H])C([H])=C2C(=C1[H])[C@]13C([H])([H])C([H])([H])N(C([H])([H])C4([H])C([H])([H])C([H])([H])C4([H])[H])[C@]([H])(C2([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H]
[H]N([H])C1=C(C#N)C(=C([H])C(=N1)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(O1)C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])N(C1=O)C([H])([H])C([H])([H])OC([H])([H])[H])C(=O)N([H])C([H])([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2C(=O)C1([H])[H]
[H]N(C(=O)C([H])([H])N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])=C(C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C([H])C2=C(N([H])C3=C4C(=C5C(=O)N([H])C([H])([H])C5=C23)C([H])([H])C([H])([H])C4([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])N=C(N=C1N([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])N([H])C([H])([H])C([H])([H])N([H])[H]
[H]ON(C(=O)N([H])C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[C@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@]([H])(C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C([H])=C([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(OC(=O)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]23[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C(O[H])=C1[H])[C@@]1([H])N([H])N=C(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])[N+](=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C(C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=N[C@@](C2=C([H])C(=C([H])C([H])=C2F)C([H])([H])C(=O)C2=NC([H])=C(N=C2[H])C([H])([H])[H])(C([H])([H])[H])C(F)(F)C([H])([H])S1
[H]C1=C(F)C([H])=C(F)C(=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])[C@]2(C3=C([H])C(Cl)=C(C([H])=C3[C@]([H])(C2([H])[H])C(C2=NOC(=N2)C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])=C(N(C2=O)C([H])([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])\N=C(/C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=NOC4=C([H])C(F)=C([H])C([H])=C34)C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C2=C(OC3=C([H])C(=C([H])C([H])=C23)S(=O)(=O)C2=C([H])C([H])=C([H])C(F)=C2[H])[C@]11C([H])([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N(N=NC2=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]C([H])([H])OC1=NOC2=C1C([H])([H])[N@@+]([H])(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NOC(=N1)C1=C([H])C([H])=C([H])C([H])=C1SC([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C([H])C(Cl)=N2)C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@]2([H])[C@@]4([H])[C@]([H])(C(=C([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]4(C(=O)OC([H])([H])N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]32C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]\C(C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])=C1\C([H])([H])N2[C@]3([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]1([H])C3([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NN=C(S1)N=C(N([H])[H])N([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C23)C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1C(OC([H])([H])C([H])([H])N1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=NN2[H])C1=C([H])C([H])=C(OC([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C(Cl)=C1[H]
[H]C1=NC([H])=C(OC([H])([H])[C@@]2([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C3=C(C([H])=C2[H])N(C(=O)C3=C(C#N)C#N)C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
C(CCCCN1C(=NC(=C1C1=CC=CC=C1)C1=CC=CC=C1)C1=CC=CC=C1)CCCN1C(=NC(=C1C1=CC=CC=C1)C1=CC=CC=C1)C1=CC=CC=C1
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[C@]([H])(N([H])C(=O)C([H])([H])C1=C(Cl)C([H])=C([H])C(N([H])C([H])([H])C(F)(F)C2=NC([H])=C([H])C([H])=C2[H])=[N+]1[O-])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]1(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])N(C(=O)N([H])C2=C([H])C([H])=C(F)C([H])=C2[H])[C@@]([H])(C(=O)N([H])C2=C(F)C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)C([H])([H])[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[H])C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]N(N1C2=C([H])C([H])=C(Cl)C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C([H])C(=C([H])C([H])=C12)C1=C([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=NOC([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(Cl)=C1[H])C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])N([H])[H]
[H]N([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N([C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C(F)C([H])=C([H])C(F)=C3OC([H])([H])[C@@]2([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C([H])C([H])=C(\N=C3/OC([H])([H])C4(C([H])([H])N3C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C2=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1N=NN=C1[C@]([H])(N([H])C(=O)C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(N([H])C([H])([H])[H])C(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(O[C@]([H])(C([H])([H])[H])C([H])([H])N([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])N1C(=NC2=C([H])C(=C([H])C([H])=C12)C(=O)N(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])C(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC(=O)[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])=C(C3=C([H])C([H])=C([H])C(Cl)=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1N1N=C(C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(F)(F)F)C([H])([H])C(=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])SC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(OP(=O)(O[H])O[H])C([H])=C1[H]
[H]N([H])C1=C([H])C2=NC([H])=NC(N([H])C3=C([H])C([H])=C(C([H])=C3[H])N(C([H])([H])[H])C([H])([H])[H])=C2C([H])=N1
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]N(C1=NC([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C(C([H])=C1[H])[C@@]([H])(N(C1=C([H])C(F)=C([H])C([H])=C1F)S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H])C1=NC([H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C([H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(Br)=C(N([H])S(=O)(=O)C2=C(F)C(F)=C(F)C(F)=C2F)C([H])=C1[H]
[H]N1C(=O)S[C@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])O\N=C(\C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C(Cl)C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C2N=C([H])N(\C([H])=C(/[H])C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C2=NC(OC([H])([H])C([H])([H])OC([H])([H])[H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])P(=O)(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1N1N=C(N=C1C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(F)C([H])=C2F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(O1)C([H])([H])N1C(SC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])=NC2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]N1C([H])=C(C2=C([H])C(=C([H])C([H])=C12)N1C([H])=NN=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C(OC2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(OC([H])([H])C([H])([H])OC2=NC([H])=C([H])C3=C2C([H])=C([H])C([H])=C3[H])=NC([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C(=O)N1C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[C@@]1([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C1=C(N=C(O1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C(=O)N1N=C(C2=C1C([H])([H])[C@]1([H])[C@@]2([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN=C(S1)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2OC1=O)C([H])([H])C1=C([H])C([H])=C([H])O1
[H]O[C@]1([H])C([H])([H])[C@]([H])(C2=C(N([H])C(=N[H])N([H])[H])C([H])=C([H])C([H])=N2)[C@@]([H])(C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]O[C@@]1(C#CC([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])OC([H])([H])C4=C([H])C(=O)C([H])([H])C([H])([H])C4=C3[C@@]([H])(C3=C([H])C([H])=C(C([H])=C3[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]12C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])=O)N([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)C2=C(OC([H])([H])[H])C([H])=C(O[H])C(=C2O[H])C([H])([H])[C@]([H])(C(=C([H])[H])C([H])([H])[H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C(O[H])=C1[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]2(O[H])C(=O)C([H])([H])SC2=NC3=C(O2)C([H])=C([H])C([H])=C3[H])[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C(=O)C([H])=C([H])[C@]3(C([H])([H])[H])[C@@]12[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C([H])([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(=NS1)C([H])([H])[H])C1=NC(SC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])N2C1=NC([H])=C2C1=C([H])N([H])N=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])S1)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])N1C(=NC(C(=O)N([H])C([H])([H])C2=C([H])C(F)=C(C([H])=C2[H])C([H])([H])[H])=C1C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(\N=C(\C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])/C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C([H])([H])[H]
[H]N1N=C(C2=C(C1=O)C([H])([H])C([H])([H])C([H])([H])N2[H])C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(N=C(N2C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=NC([H])=C(Br)C([H])=C3N(C(=O)C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=N1
[H]O[C@]([H])(C([H])([H])OC1=C([H])C2=C(N([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)[C@@]1([H])N2C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[C@@]2([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])(C(F)(F)F)C(F)(F)F
[H]N([H])C1=N[C@@]([H])(C([H])([H])C(\[H])=C(/[H])C([H])([H])[H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(C1=C([H])C([H])=C([H])N=C1[H])(C1=C([H])C([H])=C([H])N=C1[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C2=C(C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])[H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1([H])[H]
[H]N1C([H])([H])C2=C(N(C([H])=C2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OS(=O)(=O)O[H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]1([H])C(=O)N(C([H])([H])C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H]
[H]O[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])OC1=C(C([H])=C(Cl)C(N([H])[H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])[H])C([H])([H])C6=C([H])C([H])=NC([H])=C6[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C([H])=C1[H]
[H]C1=NN(C([H])=C1C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=NO[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]OC1(C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C2=C(N(N=C2[H])C2=C(F)C([H])=C([H])C([H])=C2F)N(C1=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1OC([H])([H])[H])C(=O)C([H])=C(O2)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(=NN1[H])C1=C([H])C([H])=C(N([H])C(=O)OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)O[H]
[H]OC(=O)C1=C(N([H])C(=O)N([H])[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=NC([H])=C2OC([H])([H])C([H])([H])OC2=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C(Cl)C([H])=NC3=C([H])C([H])=C(OC([H])([H])[H])N=C23)C([H])([H])C1([H])[H]
CC1=CC=C(C=C1C)C1=NN(C(C1)C1=CC=C(C=C1)N(O)=O)C(N)=S
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C(=C([H])N2[H])C(=O)C(F)(F)F
[H]C1=NC(=C([H])N1C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])N(N=N1)C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])N=C12)C([H])([H])[H]
[H]N1C(=O)C2=NN(C([H])=C2C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
CC1=CC=C(C=C1C(=O)NCC1=NC=NC=C1)N1N=C(C=C1NC(=O)NC1=C2C=CC=CC2=CC=C1)C(C)(C)C
[H]N([H])C(=O)C1=C([H])C([H])=C2C3=C(C([H])=C(S3)C(=O)N(C3=C([H])C([H])=C([H])C([H])=C3Cl)C([H])([H])[H])C([H])([H])C([H])([H])OC2=C1[H]
[H]OC(=O)C([H])([H])N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]([H])(O[H])[C@@]([H])(N([H])C1=NC2=C(C([H])=NN2C(N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])O[H]
[H]C1=C(N=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C(=O)C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C2=C1OC([H])([H])C2([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(Br)C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])[H])C2([H])[H]
NS(=O)(=O)OC[C@H]1O[C@H](OC[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O
O\N=C/C1=CC=C2N\C(\C(=N\O)\C2=C1)=C1/C(=O)NC2=C1C=CC=C2Br
[H]OC([H])([H])[C@]1(OC(=O)\C(=C(\[H])C2=C([H])C(Cl)=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])OC(=O)[C@@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(OC2=C([H])C([H])=C([H])C([H])=C12)[C@@]1([H])N2C([H])([H])C([H])([H])C([H])([H])[C@]22C(=O)N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)C([H])([H])C1=C2N=C([H])C(=C([H])C2=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NC(OC([H])([H])[H])=C([H])C([H])=C1N1C(=NN=C1C([H])([H])OC([H])([H])[H])C1=C([H])N=C(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(S[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C(=O)C1=C(N(C2=C([H])C([H])=C([H])C(OC([H])([H])C(=O)N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C([H])C(=C(C([H])=C2N=N1)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N([H])C([H])([H])C2(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC3=C([H])C([H])=C([H])C([H])=C3OC2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])SC([H])([H])C(=O)OC([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N1C([H])=C(Cl)C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C(C([H])=C2C(=N1)N([H])[H])C([H])([H])OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1\C(S\C(=C(\[H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1=O)=N\C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=NC(Cl)=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])N=C(N2C([H])([H])C([H])([H])N(C3=NC4=C(N3[H])C([H])=C([H])C(=C4[H])C(F)(F)F)C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N([H])C(=O)C(N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)C([H])([H])C2([H])[H])(C1=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1(C2=NC([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=NN(C(=C2C([H])([H])C(=O)N([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])C#CC([H])([H])N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C1=C([H])N(N=N1)[C@]1([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]1([H])OC(=O)C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])N=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)C([H])([H])SC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CCC(=O)NC1CCN(CCCN2C(=O)COC3=C2C=C(F)C(F)=C3)CC1
[H]N([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C(Cl)=C([H])C([H])=C2Cl
[H]OC1=NC(=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])C1=C([H])C([H])=C(C2=C([H])N=C([H])O2)C(OC([H])([H])[H])=C1[H]
[H]N([H])C1=NC2=C(C(=O)C3=C([H])C([H])=C(C([H])=C23)C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(N=N1)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])P(=O)(O[H])O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]1([H])N(C(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N=C(C([H])=NC2=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C(=O)N([H])[C@]([H])(C1=C(N=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1F)C([H])([H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC([H])([H])C(=O)C(F)(F)F
[H]N(C1=C(F)C([H])=C(I)C([H])=C1[H])C1=C(F)C(F)=C([H])C([H])=C1C(=O)N1C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])O[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C2=C(N([H])C([H])([H])N([H])S2(=O)=O)C([H])=C1SC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)C#CC([H])([H])[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])N1C(=O)N(C([H])([H])C1([H])[H])[C@@]([H])(C(=O)N([H])C([H])([H])[C@@]1([H])OC([H])([H])[C@]([H])(N([H])[H])C([H])([H])O1)[C@]([H])(C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
CC(C)C1=C2NN=CC2=CC(CC(NC(=O)N2CCC(CC2)N2CC3=C(NC2=O)C=CC=C3)C(=O)N2CCC(CC2)N2CCCCC2)=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]O[C@@]1(C(=O)OC([H])([H])C2=C1C([H])=C1N(C2=O)C([H])([H])C2=C(C3=C([H])C(OC(=O)N4C([H])([H])C([H])([H])C([H])(N5C([H])([H])C([H])([H])C([H])([H])C([H])([H])C5([H])[H])C([H])([H])C4([H])[H])=C([H])C([H])=C3N=C12)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])N([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(O[H])C(F)=C1[H]
[H]\C(=C(\[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C([H])C([H])=C3[H])S2(=O)=O)C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])OC([H])([H])[H])=C([H])C([H])=C1OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[C@@]1([H])SC1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(C1=NC([H])=C(N1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])O[H]
[H]ON1C(=C([H])C2=C1C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])[C@@]4([H])[C@@]5([H])C([H])([H])C([H])([H])C([H])([H])[C@@]4(C([H])([H])C([H])([H])[C@]5([H])O[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C2=C(C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(Br)C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C([H])C(=N2)C([H])([H])[H])C1=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1N=C(C2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]O\C(N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C1\C(=O)N(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=C(N(C(=N2)C(F)(F)F)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H]
[H]C1=C([H])C2=C(N=C(C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C2C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C([H])(F)F)C([H])([H])C([H])(F)F
[H]N([H])C1=NC(=NN1C(=O)C1=C(F)C([H])=C([H])C([H])=C1F)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)C([H])([H])C([H])([H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])[N+]([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])N1C([H])([H])C2=C(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3OC2=O)C([H])([H])C1([H])[H]
[H]C#CC([H])([H])N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C(OC2=C(N([H])S(=O)(=O)C3=C([H])C(Cl)=C(C([H])=C3[H])C([H])([H])[H])C([H])=C(C([H])=C2[H])C(=O)N([H])C([H])([H])C([H])([H])[H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C(=O)C1([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H])C1=NN=C(SC([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)S1
[H]C1=C([H])C2=C(C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C(=O)C4=C([H])C([H])=C(OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])O2
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(N([H])C(=O)C1=NC(=NO1)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=S)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
O\C(\C=C\C1=CC=C(C=C1)[N+]([O-])=O)=C/C(=O)C1=CC=CC=C1O
[H]N(C(=O)C([H])([H])OC(=O)C1=C([H])C([H])=C(S1)[N+]([O-])=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=N1
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC(=O)N(C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C([H])C(=C([H])C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])=C1N2C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NN(C2=C1C([H])=C(C([H])=C2[H])N1C([H])=C([H])C2=C(C([H])=C(O2)C2=C([H])C([H])=C([H])C([H])=C2Cl)C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=C([H])N=C1N([H])C([H])([H])C1=C([H])N=C([H])N1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C(N=C(N=C1[H])C([H])([H])[H])N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(OC(=O)C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1=NC([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=NC([H])=C([H])S2)=C1[H])C(F)(F)F
[H]N1C([H])=C([H])C2=C(C([H])=C([H])C([H])=C12)C1=NC([H])=C(N=C1[H])N1C([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N1C(SC([H])([H])C([H])([H])C([H])([H])[H])=C2C3=C(C([H])=C([H])C([H])=C13)[C@@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C2([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])=C(C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N=C1[H])N([H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])N(C#N)C([H])([H])C1([H])[H]
[H]OC1=C2O[C@@]3([H])C4=C(C5=C(N4[H])C([H])=C([H])C(N([H])C(=N\C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])\N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C5[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N1C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=NC2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])=C(C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])O2
[H]N(C1=NC(=NC2=C([H])C([H])=C([H])C([H])=C12)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=N\OC([H])([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(\C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])\C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]1([H])N(C([H])([H])C2=C(C([H])=C(C([H])=C2[H])C(=O)N([H])C([H])([H])[H])N(C(=O)C([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H]
[H]C1=C(C2=NSN=C2OC([H])([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])[H])C([H])=C2OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C(Cl)=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C([H])([H])C([H])([H])OC(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)[N+]([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(N1C(=O)C([H])=C2C([H])=C3OC([H])([H])OC3=C([H])C2=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C2C([H])=C3N(C2=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])N([H])C3=O)C1=NC(=C([H])S1)C(=O)N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=NC(=NC2=C1C([H])([H])C([H])([H])N(C1=NC([H])=C([H])C([H])=C1C(F)(F)F)C([H])([H])C2([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(\[H])=C(\C(\[H])=C(/[H])\C(\F)=C(/C1=C([H])C(=C([H])C(=C1OC([H])([H])C([H])(F)F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])/C([H])([H])[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C([H])N=C1[H])C1=NC([H])=C2N([H])N=C([H])C2=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C1=NC2=C(N1[H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C2N(C(=O)C(F)(F)C2=C([H])C([H])=C1[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])C3=C([H])C([H])=C(C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])=C2OC1([H])[H]
[H]OC(=O)[C@]1([H])C([H])([H])N([H])[C@]([H])(C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C(=C(S3)C(F)(F)F)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1([H])[H]
[H]O[C@]1([H])[C@]([H])(O[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])[C@@]2([H])C([H])([H])OC([H])([H])C2([H])[H])[C@@]1(O[H])C([H])([H])[H])C([H])([H])OC(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=N[C@]2([H])[C@]([H])(Cl)[C@]2([H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(Cl)SC(Cl)=C1[H])C([H])([H])N([H])C(=O)C1=NO[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C1([H])[H]
[H]ON([H])C(=O)[C@@](C([H])([H])[H])(C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])SC([H])=N1
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(F)C([H])=C2[H])[C@]1([H])C([H])([H])OC2=C([H])C([H])=C3C(C(=O)N([H])C([H])([H])C3([H])[H])=C2C1([H])[H]
[H]N1C(=S)N(C(=O)C1(C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1C(=O)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])C(=O)N([H])C1=C([H])C(Br)=C([H])C(=C1[H])C(F)(F)F)C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)N([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=NC3=C([H])C(=C([H])C([H])=C3N2C([H])([H])[H])C2(C(=O)N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C(C(=NN1C([H])([H])C1=C(OC([H])([H])C(=O)O[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1Cl
[H]N=C(N([H])[H])C1=C([H])C(O[C@]([H])(C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N([H])C1=N[C@@](C2=C([H])C(=C([H])C([H])=C2F)C([H])([H])C(=O)C2=NC([H])=C(N=C2[H])C([H])([H])C([H])([H])C(F)(F)F)(C([H])([H])[H])C([H])([H])C([H])([H])S1
[H]N([H])C(=S)N([H])\N=C(\C1=C([H])C([H])=C([H])C(Br)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]C1=C(ON=C1C([H])([H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(N2C([H])([H])C([H])([H])N([C@@]([H])(C([H])([H])[H])C2([H])[H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]2([H])C3=C(C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C(Cl)=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])N2N(C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C3=C4C([H])=C([H])C([H])=C([H])C4=C([H])C([H])=N3)C2=O)C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C(=O)O[C@@]1([H])OC([H])([H])C([H])([H])[H]
[H]N1C([H])=NC([H])=C1C1=C([H])C2=C(C([H])=C1[H])N(C(=O)N2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1=NC(O[C@]2([H])C([H])([H])[C@@]3([H])N(C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C([H])C([H])=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(F)C([H])=C([H])C(=C1[H])[N+]([O-])=O)C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]C1=C2C(Cl)=C([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])[C@](OC(=O)C([H])([H])[H])(C(=O)C([H])([H])[H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])[C@@]2([H])C([H])([H])[C@@]2([H])C1=O
[H]N(C(=O)C1=C([H])C([H])=C(I)S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=NN(C(=C2C([H])([H])C#N)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C1C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C3=C(N=C2[H])C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C(C2=C(C3=C([H])C(OC([H])([H])[H])=C([H])C(=C3N=C12)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1(C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(C(=O)OC([H])([H])[H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(N1[H])C([H])([H])C([H])([H])[H]
[H]\C(C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])=C1/C(=O)ON=C1C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])\C([H])=C([H])\C([H])([H])[C@@]([H])(C([H])([H])N2C([H])=C([H])C3=C2C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2(N([H])C(=O)[C@@]1([H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C(=O)N([H])[H]
[H]C1=C([H])C(=C2N=C(N(C(=O)C2=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C(F)(F)F
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])C([H])=C(C2=C([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]O\N=C1/C(=O)N(C2=C([H])C([H])=C([H])C(=C12)C([H])([H])[H])C([H])([H])C1=C2OC([H])([H])OC([H])([H])C2=C([H])C(F)=C1[H]
[H]N(C(=O)C([H])([H])N1N=C(C2=C([H])C([H])=C([H])C([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(N([H])C([H])([H])[H])=C1[H]
[H]N=C(N([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])N([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]C1=NC([H])=C(C#CC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C(F)(F)F)C(F)(F)F
[H]OC(=O)[C@]([H])(O[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)N([H])C1=C([H])C([H])=C(C#N)C(=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])C([H])([H])N(C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])N(C([H])=N1)C([H])([H])[H]
[H]N([H])C1=C(Br)C(=NC2=C(C([H])=NN12)C1=C([H])N(N=C1[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(Cl)C(=C1[H])C1=C([H])C2=C(N=C(N=C2[H])N([H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])N2N1C(=O)C([H])([H])C2([H])[H]
[H]\C(=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C1=NN=C(S1)C1=NC([H])=C([H])C([H])=C1[H]
[H]N1C2=NC3=C([H])C([H])=C(Cl)C(Cl)=C3C([H])([H])N2C([H])([H])C1=O
[H]OC1=C([H])C([H])=C2C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(N([H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C(O[H])=C(Cl)C([H])=C1C1=C(N([H])C(=O)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=NO1)C(=O)N([H])C([H])([H])C([H])([H])[H]
[H]N([C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])S(=O)(=O)C1=C([H])C(F)=C(Br)C([H])=C1F
[H]C1=NN(C([H])=C1[H])C1=C([H])C([H])=NC(=C1[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C(N=C3[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(C2=NC(=C3N2N=C([H])N=C3N([H])[H])C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C(F)=C2[H])C1([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)C(=C(/[H])\C(\[H])=C(/[H])C([H])([H])[H])\C([H])([H])[H])C([H])([H])C2=C([H])C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2C1([H])[H]
[H]N(C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C(Cl)C([H])=C([H])C(Cl)=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C(=N[H])N([H])[H]
[H]OC(=O)[C@]1([H])N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC([H])([H])C1=NC2=C(S1)C([H])=C([H])C(N([H])C(=O)C1=C([H])C([H])=C(OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])=C2[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2N=C(SC([H])([H])[H])N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N([H])C1=NC2=C([H])C([H])=C([H])C3=C2C1=C([H])C([H])=C3[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]ON(C(=O)N([H])[H])[C@]([H])(C(\F)=C(/[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(F)C([H])=C2[H])O1)C([H])([H])[H]
[H]OC(=O)C1([H])N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C2([H])N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])[H])C([H])([H])C3=C([H])C([H])=C(O[H])C([H])=C3[H])C([H])([H])SSC1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(O[H])C([H])([H])[H])C([H])(O[H])C([H])([H])[H])C([H])([H])O[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])C(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])[C@](C1=C([H])N=C([H])N1C([H])([H])[H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C2N3C(=NN=C3C([H])([H])[H])C([H])=C(C3=C([H])C(Cl)=C([H])C([H])=C3[H])C2=C1[H]
[H]N(C(=O)C1=C([H])N=C(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(C#N)C([H])=C3[H])C([H])([H])C2([H])[H])C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC(=C(S1)C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H]
[H]C([H])=C(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C([H])C(=C([H])C([H])=C12)C1=C([H])SC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C(=O)C(F)(F)F)[C@@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])[C@]1(SC(=NC1=O)N([H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)C2=C(C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
CCC[C@H](CO)NC1=NC(S[C@@H](C)C2=CN=CC=C2Cl)=NC2=C1SC(=O)N2
[H]N(C1=C([H])C([H])=C(C([H])=C1[N+]([O-])=O)S(=O)(=O)N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])[H])[C@@]([H])(C([H])=O)C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H]
[H]N(C(=O)N([H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C(Cl)=C1[H])[C@@]([H])(C(=O)N1N(C#N)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C([H])C2=C1OC(=O)N2C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C(Br)C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])N([H])C(=O)C1=C(N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]N(\C(=N/C#N)N([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(F)C(F)=C([H])C([H])=C1[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])[C@@]2([H])N3C([H])([H])\C(=C(\[H])C4=C([H])C(Cl)=C(Cl)C([H])=C4[H])C1([H])C([H])([H])[C@@]3([H])C([H])([H])C2([H])[H]