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[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=NC([H])=C2N=C(N(C2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])C([H])([H])C4=C(N([H])C5=C4C([H])=C([H])C([H])=C5[H])[C@@]4([H])[C@]5([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]C1=C([H])C([H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C3=NC([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])([H])C2=C1C([H])=C(C([H])=C2[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])[C@]12[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N(N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=S)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)[C@@]([H])(C([H])([H])[H])[C@]12C([H])([H])C([H])([H])[C@](C3=C([H])C([H])=C(C([H])=C3[H])C3=NC4=C(OC3(C([H])([H])[H])C([H])([H])[H])N=C([H])N=C4N([H])[H])(C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C3=C(F)C([H])=NC(=N3)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])OC2=C([H])C([H])=C(N=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
CCN1N=CC(NC2=NC=C(C(NC)=N2)C(F)(F)F)=C1C
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@](C(=O)N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]\C(=C(\[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@@]1([H])N(C([H])([H])[C@@]([H])(N([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])N([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])SC2=C([H])C(Cl)=C(O[H])C([H])=C2O[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(OC([H])([H])C([H])([H])C(F)(F)F)C([H])=C1[H])[C@]1([H])C([H])([H])OC2=C([H])C([H])=C([H])C(C3=C([H])N=C([H])N=C3[H])=C2C1([H])[H]
[H]N(C1=C(N([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(=O)C1=O)C1=C([H])C([H])=NC(N([H])C2=C([H])N=C([H])C([H])=N2)=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])SC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C2=C([H])C([H])=C([H])C(N([H])[H])=C2[H])C(=N1)C1=C([H])C([H])=C([H])O1
[H]ON([H])C(=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(OC2=C(F)C(=C(F)C(OC3=C([H])C([H])=C([H])C(=C3[H])C(=O)N([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=N2)C([H])([H])[H])=C1[H]
[H]N([H])S(=O)(=O)C1=NC2=C([H])C([H])=C(OC([H])([H])C([H])([H])OC(=O)C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@@]4([H])[C@]5([H])C(=O)C([H])([H])[C@]6([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[C@]6(C([H])([H])[H])[C@@]5([H])C([H])([H])C(=O)[C@]34C([H])([H])[H])C([H])=C2S1
[H]OC(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(OC([H])([H])C([H])=C([H])[H])C(\[H])=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=O)[C@](O1)(C1=C([H])C([H])=C(S1)C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2N(C(=O)N([H])C([H])([H])C2=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)S(=O)(=O)C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C(Br)C(=NN1[H])C(=O)N([H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(N([H])C1=O)C([H])=C([H])C([H])=C2[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C(N=C12)C#CC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N([H])OC([H])([H])[H]
COC1=CC(\C=C2/CCC\C(=C/C3=CC(O)=C(OC)C=C3)C2=O)=CC(OC)=C1
[H]N([H])C1=NC(=C(S1)C1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=N1
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]\C(=C(\[H])C1=C(Cl)N=C(N1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C2SC3=C([H])C([H])=C([H])C([H])=C3C2=C1[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C1=NC(=NO1)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])C([H])=C1[H])C([H])([H])[H])[C@@]([H])(O[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=NN([H])C([H])=C1[H]
[H]C1=NC(=C([H])N1C([H])([H])C([H])([H])[H])C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC(C2=C([H])C([H])=C(O2)C([H])([H])[H])=C(N=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(=C2[H])C([H])([H])[H]
[H]N(C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)N3C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C2=O)C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]N(C1=NC(N([H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=N1)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C([H])([H])[N+]1(C([H])([H])[C@]2([H])O[C@]3(OC2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C1=C([H])C(SC2=NN=C([H])N2C([H])([H])[H])=C([H])C([H])=C1N([H])[H]
[H]N(C(=O)[C@]([H])(N1C(=NC2=C([H])C([H])=C(C([H])=C12)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=NC(=N2)N2C([H])=NC([H])=C2[H])[C@@]([H])(C([H])([H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(OC3=C(C([H])=C(Br)C([H])=C3[H])[C@@]3([H])O[C@]([H])(C([H])([H])N4OC5=C4C([H])=C(C#N)C([H])=C5[H])C([H])([H])[C@@]23[H])=C1[H]
[H]C1=NC2=C(N=C(C([H])=C2N1C([H])([H])[H])C1=C([H])C(=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C(F)(F)F)C#N
[H]N1C2=C(C([H])=C([H])C3=C([H])N=C(\C([H])=C(/[H])C4=C([H])C([H])=C(C([H])=C4[H])C([H])([H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C([H])=C23)C2=C1C([H])([H])N([H])C2=O
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N1C(=O)N(C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2N=C(SC2=C1[H])C1=C([H])C([H])=C(N([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])N(C2=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]1([H])N(C(=O)N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])C2([H])[H])C(=O)[C@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H])C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2F)C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]C1=C([H])C(=C([H])C([H])=C1C1=NOC(=N1)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])C2=C([H])C([H])=NC([H])=N2)C([H])=C1[H])C1=NC(=C([H])S1)C1=C(F)C([H])=C(C([H])=C1[H])C(F)(F)F
[H]O[C@@]1([H])[C@@]([H])(N([H])C(=O)C([H])([H])N2C(=O)[C@@]([H])(N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=N[H])N([H])[H]
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[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)S(=O)(=O)C([H])([H])C1=C([H])C(=C(C([H])=C1[H])N1C(=O)C2=C(OC([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])N=C3C(OC([H])([H])C([H])([H])[H])=C2C1([H])[H])C([H])([H])[H]
[H]N([H])C1=C(S[C@]([H])(C2=C([H])C(=C([H])C([H])=C2[H])[N+]([O-])=O)C([H])([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C2=C(N([H])C1=O)C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C(=C1[H])[N+]([O-])=O)C(=O)OC([H])([H])[H])C1=C([H])C([H])=C2C(=O)N([H])C(=O)C(=O)C2=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=N2)C([H])([H])C([H])([H])C2=C1C([H])=C([H])C(Cl)=C2[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C(C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C(C([H])=C(C([H])=C1[H])C1=NC(C#N)=C2N=C([H])N([H])C2=C1[H])C(F)(F)F)C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(\C([H])=C(/[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C([H])N=C(C([H])=C1[H])C([H])([H])N(C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C(C([H])=C(Br)C(=C1[H])N1N=NC2=C1N=C(N=C2N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(C1=NC(=C(S1)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(C#CC2=C([H])C(Cl)=NC(Cl)=C2[H])C([H])=C1[H]
[H]O[C@@](C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(OC([H])([H])[H])C(=O)C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=NN=C(N1C([H])([H])C([H])([H])C(F)(F)F)C([H])([H])N1C(=O)C([H])([H])OC2=C(Cl)C([H])=C(Cl)C([H])=C12
[H]ON([H])C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N1C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])N=C(OC([H])([H])C([H])([H])F)C([H])=C1[H]
NC1=NC(=CC=N1)N1C=CC2=C1C=C(O)C=C2
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=NN(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=C(\C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])\C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1(C#CC2=C([H])C([H])=C3N([H])C(=O)C([H])([H])C4=C(N([H])C5=C4C([H])=C(C([H])=C5[H])C(F)(F)F)C3=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])N=C2N(C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C(=C([H])C(N([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)O[C@@]2([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C2=C1C([H])([H])C([H])([H])O2
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C(OC([H])([H])[H])=C1\C([H])=C1/C(=O)N([H])C2=C([H])C([H])=C(F)C(C#C[C@@]3([H])N([H])C([H])([H])C([H])([H])C3([H])[H])=C12
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C1=NC([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2O1
[H]N(C1=NC(=NC2=C1N=C([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@]2([H])N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C2([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C(F)=C([H])C2=C([H])N(N=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=C([H])C2=C(C([H])=C([H])C([H])=C12)C([H])([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]N(C1=NC([H])=C(O1)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(C1=NC2=C(N=C(N=C2N=C1[H])N([H])[H])N([H])[H])C([H])([H])C([H])([H])[H])C(=O)O[H]
[H]N(C(=O)OC([H])([H])[H])C1=C(C([H])=C(N([H])C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1[H])C([H])([H])[H]
[H]C1=C(C2=C([H])C([H])=C(C([H])=C2N1C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=NC3=C2C([H])=C([H])N=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C([H])=C3[H])C(=O)N([H])C1=O)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=NC2=C1N=NN2C1=C([H])C([H])=C(Br)C([H])=C1Br)C([H])([H])[H])C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C([H])=C2N=C([H])C([H])=C(OC([H])([H])[C@@]3([H])C([H])([H])N([H])C([H])([H])C([H])([H])C3([H])[H])C2=C1[H]
C1CN=C(N1)[C@@H]1CO[C@@H](CO1)C1=CC=CC=C1
[H]O[C@@]([H])(C([H])([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C3=C1C([H])=C([H])C([H])=C3[H])C(=O)N([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C2=C(OC([H])([H])C(=O)OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=N3)=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[Na+].[Cl-].Cl[Au](Cl)Cl
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NC1=NC2=C(S1)C=C1CCN(CC3=CC=CC=N3)CCC1=C2
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[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C(F)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
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[H]C1=C([H])N2C(=NN=C2C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(OC2=C(C(Cl)=C([H])C([H])=C2[H])C([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2C#N)C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(C([H])([H])C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)C([H])([H])C(=O)O[C@]([H])(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(Cl)C([H])=C(C(OC([H])([H])C(=O)OC([H])([H])[H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C2C(=C1[H])[C@]1([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N1C2=C(C([H])=C(C([H])=N2)C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])(OC([H])([H])[H])C([H])([H])C2([H])[H])N(C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]N1N=C(\C([H])=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(SC2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C(=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)[C@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C([H])([H])N(C1=C([H])C([H])=C(C#N)C(Cl)=C1[H])[C@]1([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]OC([H])([H])C([H])([H])N([H])C1=C([H])C(=NC([H])=C1[H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
CC(OC1=C(OC=C)C=CC=C1)C1=NCCN1
[H]O[C@@]1([H])C(=O)O[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N([H])[C@@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])[C@@]([H])(N(C2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1C([H])([H])[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(Cl)=C2[H]
[H]N(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C(C(=O)C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])[C@]2([H])C([H])([H])[C@@]([H])(N([H])C3=C([H])C([H])=C(OC4=NC5=C(S4)C([H])=C([H])C([H])=C5[H])C([H])=C3[H])[C@@]1([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C(=O)N1[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H])C(F)(F)F
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@]12C([H])([H])C([H])([H])C(=O)[C@]3([H])OC4=C5C(=C([H])C([H])=C4OC([H])([H])C4([H])C([H])([H])C4([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@@]235
[H]OC(=O)[C@]([H])(C([H])([H])C([H])([H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])N=C([H])N12
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C2=C1N(C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)S(=O)(=O)C1=C([H])C([H])=C([H])S1
[H]N(C1=NC(=NC2=C(C(=NN12)C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])(C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])=C(C(=O)N2C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=NC3=C(N=C(N=C3N=C2[H])N([H])[H])N([H])[H])C([H])=C1[H])C(=O)O[H]
[H]ON([H])C(=O)C([H])([H])[C@]1(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])C3=C4C([H])=C([H])C([H])=C([H])C4=NC(=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C3N(C([H])=NC3=C([H])N=C12)C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(OC1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C1=[N+]([H])C(F)=C([H])C2=C1N=C1N2C([H])([H])[C@]([H])([N+]([H])([H])[H])[C@@]([H])(C2=C(F)C([H])=C(F)C(F)=C2[H])C1([H])[H]
[H]C1=C(Br)C([H])=C2C([H])=C(C(=O)C([H])([H])[H])C(=O)OC2=C1Br
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C#CC1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])\N=C(\C1=C([H])C([H])=C(OC([H])([H])C(=O)N([H])C2=C([H])C(=C([H])C(=C2[H])C(=N\N([H])C(=N[H])N([H])[H])\C([H])([H])[H])C(=N/N([H])C(=N[H])N([H])[H])\C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C(N([H])C(=N/C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])\N([H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1F)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C(=O)\N=C1\N2C(C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C([H])([H])C2([H])[H])=C(C#N)C([H])([H])C1([H])[H]
CCN1N=CC2=C1C1=CC(=CC=C1N(C)S2(=O)=O)C1=CC=C(CC)C=C1
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(C3=C(O2)C([H])=C([H])C(=C3OC([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])[C@]2([H])O[C@]([H])(O[C@]12[H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C(=NC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C(=C1[H])C1=NN([H])C(=O)N1C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N1N=C(C#CC2=C([H])C([H])=NC([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(S1)C([H])=C(S2)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(C#N)=C([H])C([H])=C1N([H])C(=O)N([H])C1=C(Br)C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C#CC([H])([H])[H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C(\[H])C1=C(C([H])=C([H])S1)C([H])([H])[H])C1=C(Cl)C(=O)N([H])N=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])N(C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C2=C([H])N([H])C([H])=N2)=C([H])C([H])=C1[H]
[H]C1=C(N=C2C([H])=C([H])C(Br)=C([H])N12)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(N=N2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=C(C([H])=NC2=C1C([H])=NN2C([H])([H])[C@]([H])(Cl)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])C(=O)C(=O)C1=C2C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])N1C(=O)C([H])([H])OC([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C(=C([H])N=C1[H])C1=C([H])C([H])=C(S1)C([H])([H])[H]
[H]OC(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)N([H])C2(C3=C([H])C(Cl)=C([H])C(Cl)=C13)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC1=C2N=NN=C2N=C2SC([H])([H])[C@]([H])(N12)C([H])([H])[H]
[H]C1=C(C2=C3C(OC([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C2N1C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C(=[N+]([H])[H])C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([O-])C([H])=C([H])C(=C1[H])[N+]([O-])=O
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[H]O[C@@](C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1Cl)(C([H])([H])C(C1=C([H])C(F)=C([H])C([H])=C1OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(S1)N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1[H])C(=O)O[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=C(C3=C(N=C2[H])N=C(N=C3N([H])[H])N([H])[H])C([H])([H])[H])C([H])=C1[H])C(=O)O[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N([H])C1(C2=NC([H])=C([H])S2)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]C1=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C2([H])[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)[C@@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C(=NC2([H])[H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(OC2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=N1
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1=NC(=NN1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(C2=C([H])N([H])C3=C([H])C([H])=C([H])C(Br)=C23)=C(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC(C(=O)N([H])[C@@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2O[C@]2(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C(N(C([H])([H])[H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(C#N)=C([H])N=C2C([H])=C1[H]
[H]C1=C(C([H])=C([H])C(=N1)[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C(Cl)C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=[N+](C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(I)=C(N([H])S(=O)(=O)C2=C(F)C(F)=C(F)C(F)=C2F)C([H])=C1[H]
[H]C1=C([H])C2=C(S1)C([H])([H])[C@]([H])(OC([H])([H])[H])O[C@]21C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(S1)N([H])C1=C([H])C(=C([H])C([H])=N1)C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=NC3=C(N=C(N=C3N=C2[H])N([H])[H])N([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C([H])C2=C1C(=O)C1=C(N([H])N=C21)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
CS(=O)(=O)NC1=C2N=C(C=C(O)C2=CC=C1)C(=O)NC1=CC(F)=CC=C1F
[H]N(C(=O)C1=C([H])C([H])=C2C([H])=C([H])N([H])C2=C1[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N=C1SC([H])([H])C([H])([H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C1=NN=C(N1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C(=O)C([H])([H])OC2=C([H])C([H])=C(Cl)C([H])=C12
[H]N(C(=O)[C@@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])N([H])N=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)N1C([H])([H])C([H])([H])[C@]2(C(=O)N(C3=C([H])C(F)=C([H])C([H])=C3[H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(\C(=N/S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1Cl)N1N=C([H])[C@@]([H])(C([H])([H])C([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C2N(C([H])=C([H])C2=NC([H])=N1)C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C3=C2C([H])=NS3)C(Cl)=C1[H]
[H]OC1=NC2=C(C([H])=C3C(N([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]3([H])C([H])([H])[H])=C2[H])C(=C1[H])C(F)(F)F
[H]N([H])C1=NC(SC([H])([H])C(=O)N([H])C2=C(Cl)C([H])=C(Br)C([H])=C2[H])=NC(N([H])[H])=C1[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C2=NC(=C([H])C([H])=C2[H])C2=NC(=NC(N([H])C(=O)C([H])([H])[H])=C2[H])N2N=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(\C([H])=C2\C(=O)OC3=C([H])C([H])=C([H])C([H])=C23)=C([H])C(O[H])=C1O[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])P1(=O)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C(C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C#N)C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C(Cl)=C([H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H])[C@@]1([H])C([H])([H])N(C(=O)C([H])=C([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(C2=NN([H])N=N2)(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1C1=NN([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
COC1=CC=CC(C[C@@H]2O[C@H]([C@H](N(C)C2=O)C2=CC=C(Br)C=C2)C2=CC=C(Br)C=C2)=C1
[H]C1=C(ON=C1C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C(C([H])=C(C([H])=C3[H])C3=NC(=C(S3)C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])C([H])(N([H])C1=NC([H])=C(S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])P(=O)(O[H])O[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C2=NC(N([H])[C@]34C([H])([H])[C@@]5([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C5([H])[H])C3([H])[H])C4([H])[H])=C(C([H])=N2)[N+]([O-])=O)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=S)N(C([H])([H])C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]C1=C([H])N(C([H])=N1)N(C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C([H])C(=C2C([H])=C1[H])[N+]([O-])=O)N1C(=O)N2[C@@]([H])(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1[H])C1=C([H])C2=C(C([H])=C1Cl)C(=O)N([H])C([H])=C2[H]
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[H]OC1=C(OC([H])([H])[H])C(C(=O)N([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])=C(Cl)C(=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)O1)C1=C([H])C([H])=C([H])C(=C1N1C([H])([H])C([H])([H])C2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=O)OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])N(C2=C([H])C(=C1[H])C(F)(F)F)[C@@]([H])(C1=NN(N=N1)C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])C#CC1=C([H])N=C([H])C([H])=C1[H]
[H]C1=NN(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=C([H])C(=C1[H])[N+]([O-])=O)C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2F)C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C2N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(N(C3=NN(N=N3)C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C2=C([H])C(=C1[H])C(F)(F)F
[H]ON(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])[C@]([H])(C1=C([H])C2=C(OC(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])N=C(C(OC2([H])C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C1=NN(C(OC([H])([H])C([H])([H])C2=NC3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N3[H])=C1[H])C([H])([H])C([H])([H])O[H]
[H]OC1=C2C(=O)C3=C(C(=O)C2=C(O[H])C2=C1C([H])([H])[C@@](O[H])(C(=O)C([H])([H])[H])C([H])([H])[C@]2([H])O[C@]1([H])O[C@@]([H])(C([H])([H])[H])[C@@]([H])(O[H])[C@@]([H])(N([H])[H])C1([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C3[H]
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])C1=C(OC2=C3C([H])=C(SC3=C([H])N=C2[H])C(=O)N([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC(=C(S1)C(=O)N([H])C1=C(Cl)C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C1=NN=C(O1)C1=C([H])N2N=C([H])N=C(N([H])C3=C(F)C([H])=C(F)C(=C3[H])C(=O)N([H])C3([H])C([H])([H])C3([H])[H])C2=C1C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=C([H])C2=C1C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]C#CC([H])([H])N1C([H])([H])C2=C(N([H])[H])C3=C([H])C(C#N)=C(N=C3N=C2C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2C2=NC3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
[H]N1C(=NC(=C1C1=NC2=C(N=C([H])N2C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]N(C(=O)C([H])([H])OC1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(C#N)=C([H])C([H])=C2O1
[H]N([H])C1=C(\C([H])=N\OC([H])([H])[H])C(=NC([H])=N1)N([H])C1=C([H])C2=C(N([H])C(=N2)C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
CN1CCN(CC1)C1CC2=C(SC3=C1C=C(C=C3)C1=CC=NC=C1)C=CC=C2
[H]C1=C(OC([H])([H])[H])C(C2=C3N=C(N=C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C3=C([H])C(O[H])=C([H])C([H])=C3N2[H])C2=C1C(=O)N([H])C2=O
[H]N(C(=O)C1=C(C([H])=C([H])S1)S(=O)(=O)N([H])C1=C(Br)C(=NO1)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]ON1C2=C3C4=C1C(=O)OC([H])([H])[C@]1([H])N([H])C(=O)C5=C([H])SC(=N5)[C@@]([H])(N([H])C(=O)C5=C([H])SC(=N5)\C(N([H])C(=O)[C@@]([H])(N([H])C(=O)C5=C([H])SC(=N5)C5=C([H])C(OC([H])([H])[H])=C(N=C5C5=C([H])SC1=N5)C1=NC(=C([H])S1)C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]([H])(O[H])C([H])([H])[H])=C(/OC([H])([H])[H])C([H])([H])[H])[C@]([H])(OC4([H])[H])[C@]([H])(O[C@]1([H])O[C@@]([H])(C([H])([H])[H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])[C@](O[H])(C([H])([H])[H])C1([H])[H])C(=O)OC([H])([H])C3=C([H])C([H])=C2[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C(Cl)C([H])=C1C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C(OC(F)(F)F)C([H])=C([H])C(N([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])[C@]1(N(C(=O)N([H])C1=O)C([H])([H])[H])C2([H])[H]
[H]N1N=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N([H])C(=O)C([H])([H])SC1=NN=C(N1N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])Cl)C(=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C1=C([H])C(=NC(=N1)N([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N1C([H])([H])[C@]([H])(O[H])[C@@]([H])(O[H])C1([H])[H]
[H]OC1=C(N([H])C2=C3C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C([H])C3=NC3=C2C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C3[H])C([H])=C([H])C([H])=C1[H]
COC1=CC=C(C=C1)C(CCC(N)C(O)=O)(C1=CC=CC=C1)C1=CC=CC=C1
[H]C1=C(OC2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C2C(OC3(C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])=C1[H]
[H]N1C(=O)S[C@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])SSC([H])([H])C2([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC(C2=NN([H])C3=C([H])C([H])=C([H])C([H])=C23)=C(Cl)C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N=C1OC([H])([H])C([H])([H])N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]OC(=O)C1=C([H])C(\N=C2\S\C(=C(\[H])C3=C(Cl)C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C(=O)N2C([H])([H])[H])=C([H])C([H])=C1[H]
[H]S\C(=N/C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@@]2([H])OC([H])([H])C(=O)[C@@]12[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C(OC2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC2=NC([H])=C(Br)C([H])=N2)=NC(=N1)C1=NC([H])=C([H])C([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1Cl)C(=O)OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC(=O)C3=C([H])C(Cl)=C(N([H])[H])C([H])=C3OC([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2N=C([H])C(=N2)C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=C([H])C(OC(=O)C2=C([H])C(=C([H])S2)C([H])([H])[H])=NN1S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])C1=C([H])C2=C(C([H])=C1[H])C(=C([H])N2[H])C1=C([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])S1
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C(OC([H])([H])[H])=C(C#N)C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[C@@]2([H])SC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N3C(O[H])=NC4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C1=NC(=C([H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])S2)C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])C1=C2N(C([H])=N1)C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C21
CCOC(=O)CNC(=O)C(=O)C(COCC1=CC=CC=C1)NC(=O)[C@H](CC1CCCCC1)NC(=O)C1=CC(=CC(Cl)=C1)N(O)=O
NCC1=C(C=C(N1)C1=CC=NC=C1)C(N)=O
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=NC([H])=NC2=C([H])N=C(C([H])=C12)C1=C([H])C([H])=C(O1)C([H])([H])N([H])C([H])([H])C(=O)OC([H])([H])[H]
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[H]N(C1=C2C([H])=C([H])C([H])=C([H])C2=NC([H])=N1)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
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[H]OC(=O)C([H])([H])C1=C(N2N=C(C([H])=C([H])C2=O)C2=C3C([H])=C([H])C([H])=C([H])N3N=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C2N(C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(OC2=C([H])C([H])=C(C([H])=C2[H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C2=NN=NN2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
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[H]N1C(=O)N(C2=C1C([H])=C(F)C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])OC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C(Br)=C([H])C([H])=C2C2=C1C([H])=NC([H])([H])C2([H])[H]
[H]C1=NC(=C([H])C(=N1)N1C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(SC2=C(C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C(F)(F)F
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC(=O)C([H])([H])OC1=C(C([H])=C(C([H])=C1[H])C(C1=C([H])C([H])=C(OC([H])([H])C2=C(ON=C2C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C([H])([H])[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
Cc1cnc(Nc2cc(Cl)cc(Cl)c2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
[H]N(C(=O)[C@]1([H])N([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C(C([H])([H])N2C(=O)OC([H])([H])C2(C([H])([H])[H])C([H])([H])[H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C1=C(OC([H])([H])C2=C(C3=C([H])C([H])=C([H])C([H])=C3S2)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
OC(=O)C1=CC=CC(=C1)C1=CC=C(O1)\C=C1/SC2=NC3=C(CCC4=CC=CC=C34)C(N2C1=O)C1=CC=CC(=C1)N(O)=O
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C2=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C1=C(C2=C([H])C([H])=C([H])C([H])=C2O1)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])C(F)(F)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C(F)(F)F)C(F)(F)F)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C([H])C(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)N2C([H])=NN=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(Cl)=C(SC([H])([H])C([H])([H])C([H])([H])OC2=C(C3=C(C([H])=C2[H])C(=NO3)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C([H])C(Cl)=C2C2=C1C1=C(N([H])C(C([H])=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(OC3=NC(=NC(=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=N3)C([H])=C([H])C([H])=C2S1
[H]C1=C(C2=C3N=C(C([H])=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])C(=C([H])C(=N1)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C(C2=C([H])C([H])=C(O2)C([H])([H])[H])=C1C#N)C1=C([H])C([H])=C([H])O1
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(=C13)C2([H])[H]
[H]N([H])C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C([H])=N1)C1=C([H])C(=NC([H])=C1[H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])N2C(=NC(=NC2(C([H])([H])[H])C([H])([H])[H])N([H])[H])N([H])[H])=C([H])C([H])=C1[H]
CC1=CC(=CC(C)=C1)C(=O)NOCCCCCC(=O)NO
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])[H])C(SSC1([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=NC(SC([H])([H])[H])=N1)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=N/[C@@]1([H])C([H])([H])C2=C([H])C([H])([H])[C@@]3([H])[C@@]4([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)C([H])([H])[H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H])\N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C([H])([H])N1C([H])=NC(=C1C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C(N=C1C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])=C([H])C(=C2[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H][C@]12CN(CCC)Cc3c(C)ccc(Cc4c(O)c(O)ccc14)c23
[H]N([H])C1=NC2=C([H])C(=NC([H])=C2C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@]1([H])[C@]([H])(N(C([H])([H])C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])[C@@]2([H])C3=C([H])C([H])=C([H])C(=O)N3C([H])([H])[C@@]12[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=NC2=C1SC1=NC3=C(C(=C21)C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H]
[H]N1C2=C(N=C1C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])[C@@]2([H])[C@]3([H])O[C@]4(O[C@]3(C(=C([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]2(O4)[C@]2([H])C([H])=C(C(=O)[C@@]2(O[H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])N=N1)C([H])([H])C#N
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[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N=C([H])N=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C(=C1[H])C([H])([H])N(C(=O)[C@@]([H])(C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(Cl)C([H])=C(C([H])=C1Cl)C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C(Cl)C([H])=C2[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C1=NC2=C(N=C([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])N1C(=O)C(=C([H])C2=C([H])N=C(N=C12)N([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
COC1=CC2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=CC=C(N=C3)C3=CC=CC=C3O)C2=O)C=C1
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C2=C(N=C([H])N=C2N([H])C2=C([H])C(Br)=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]OC(=O)C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OP(=O)(O[H])O[H])C([H])=C1[H])C([H])([H])O[H])C([H])([H])C(=O)O[H]
[H]N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)N([H])C2=C3C(=O)C4=C(N([H])N=C4C3=C([H])C([H])=C2[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N([H])C1=NC(=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(N([H])[H])=C(C([H])=C1C([H])([H])[H])S(=O)(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
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[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(S1)C#CC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
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[H]N([H])C(=O)C1=C(SC([H])=C1[H])N([H])C(=O)C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C(F)=C([H])C([H])=C1SC1=NC2=C(C([H])=C1[H])N(C(=O)N([H])C2([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
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[H]C1=C([H])N(N=N1)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C(N=C3[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C2=C(S1)C(=NC(=N2)N(C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C([H])N=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])([H])[C@@]2([H])C(=C1[H])C([H])([H])O[C@]2([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C3=C([H])C(C#N)=C([H])C([H])=C23)C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2=O)C([H])([H])[C@@]1([H])N(C2=C([H])C([H])=C([H])C([H])=C2C(=NC1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H]
[H]N([H])C1=NN([H])C([H])=C1C(=O)N([H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])S1)C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC2=C3C([H])=C([H])N(C3=NC([H])=N2)C([H])([H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]O\C(OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1\C(=NC(C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]1([H])C#CC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=S)OC([H])([H])C1=C([H])C(F)=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1N=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=O
[H]C1=C([H])C(=C([H])C([H])=C1F)[C@@]1([H])OC2=C([H])C(=C([H])C([H])=C2C(=O)C1([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C1[H])C(C1=C([H])C([H])=C(F)C([H])=C1[H])=C(N(C2=O)C([H])([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])N([C@]([H])(C4=C([H])C([H])=C(C([H])=C4[H])C(F)(F)F)C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N=C(O1)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C(=NN(\C(=N\S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N=C(C1=C([H])C([H])=C([H])S1)C([H])([H])C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN=C(S1)C(F)(F)F
[H]C1=C2C(=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C1=C([H])C([H])=C(SC([H])([H])[H])C(=O)C([H])=C1[C@@]([H])(OC(=O)[C@]13OC(=O)[C@](C([H])([H])[H])(C([H])([H])C1([H])[H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C1=NC([H])=C2C([H])=C(C(=O)N(C2=C1[H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C2S[C@]([H])(C([H])([H])[H])C([H])([H])C3=C2C(=C([H])C([H])=C3OC([H])([H])C2=C([H])C([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])N(C(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C1([H])[H])[C@]1([H])C2=NC([H])=C(Br)C([H])=C2C([H])([H])C([H])([H])C2=C1C([H])=C([H])C(Cl)=C2[H])C1=NN=C([H])S1
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])S(=O)(=O)C([H])=C([H])[H])C([H])([H])C1=C([H])SC([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
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[H]N(C(=O)C([H])([H])[H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C1([H])[H])[C@]1([H])N=C([H])C(=N1)C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@]1([H])N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C2=C([H])C(=NC(=N2)N2C([H])=NC([H])=C2[H])C([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(C(=O)C([H])([H])C1=C(N([H])N=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1Cl)C(F)(F)F
[H]N([H])[C@@]1([H])C([H])([H])N(C(=O)N([H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2C(=O)C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])[C@]2([H])C3=C(C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C(=C1[H])N(C([H])=C(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C(O[H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC([H])([H])C([H])([H])C([H])([H])C#CC1=C([H])C([H])=C([H])C(N([H])C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)=C1[H]
[H]N1C([H])([H])[C@]2([H])C3=C([H])C(F)=C([H])C([H])=C3[C@@]([H])(C([H])([H])[H])[C@]2([H])C1([H])[H]
[H]N(N1C(SC([H])([H])SC2=NN=C(N2N([H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])SC(=N2)N([H])C(=O)C([H])([H])Cl)=NN=C1C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C([H])([H])Cl)C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]SC1=NN=C(N1N([H])[H])C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=C(OC2=C1C=C(C=C2)C1=CC=CC=C1)C(=O)NC1=CN=C(C=C1)N1CCC(COC2=CC=CC(CC(O)=O)=C2)CC1
Cc1cnc(Nn2cccc2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Br)C([H])=C([H])C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])N=C([H])C2=C1[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])OC2=C(Br)N=C(C([H])=C2[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]C1=NC([H])=C2N=C(N(C(=O)C2=C1[H])C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)O[H]
[H]C1=C([H])C([H])=C2N(C(=O)C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C3=C(SC2=C1[H])C([H])=C([H])C(=C3[H])C(F)(F)F
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(S[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C(=C([H])C([H])=N1)C([H])([H])N([H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=C([H])C2=C(OC(F)(F)O2)C([H])=C1[H]
ClC1=CC=CC=C1C1=NC2=C(N1)C(=O)N(CC1=CC=CC=C1)C1=C2C=CC(Br)=C1
[H]C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)[C@]1(C(=O)N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])SC1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(C#N)=C2C(=C1[H])C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=NC([H])=C([H])N=C2N1[H]
[H]N([H])C1=NC(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC([H])([H])[C@@]1(F)C([H])([H])N(C([H])([H])C2=C([H])N([H])C3=C2N=C([H])N([H])C3=O)C([H])([H])[C@]1([H])O[H]
[H]C1=NC([H])=C2N=C(N(C2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(C2=NN=C(N2C([H])([H])[H])[C@@]23C([H])([H])C([H])([H])[C@@](C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])C2([H])[H])C([H])([H])C3([H])[H])=C(C([H])=C1[H])C(F)(F)F
[H]C([H])=C([H])C([H])([H])SC1=NC2=C([H])C([H])=C(N([H])C([H])([H])C([H])=C([H])[H])C([H])=C2C(=O)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(SC([H])=C1[H])N([H])C(=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])N([H])C(=O)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C(N=C(N(C2=C(Cl)C([H])=C(Cl)C([H])=N2)C([H])([H])[H])C(=N1)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])F
[H]OC(=O)C([H])([H])C([H])([H])N([H])C([H])([H])C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N1C2=NN(C([H])=C2C2=NC(=NN2C1=O)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(Cl)=C([H])N=C1N([H])C(=N[H])N([H])[H]
[H]OC1=C([H])C(O[H])=C2C(=O)C([H])=C(OC2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C(=N\C1=C([H])C([H])=C(Cl)C([H])=C1[H])\C(=O)C([H])([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2N(C(=N3)C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=C1C([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])[C@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C(N2C(=O)N(C3=C2N=C(N=C3N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(Br)=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C2N=C(N=C1[H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)C1=C([H])C([H])=C(O[C@@]([H])(C([O-])=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]C1=C(Cl)C(=C([H])C(=C1[H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[N+]([O-])=O
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(O[H])=C([H])C(C([H])=O)=C2O1
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])N(C2=C([H])C3=C(C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C(=NN2[H])C1=NC2=C([H])C(=C([H])C([H])=C2N1[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@]1([H])N=C2SC(C(=O)N3C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C3([H])[H])=C(N2[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(C3=C1[C@]1([H])OC4=C(OC([H])([H])[H])C([H])=C([H])C5=C4[C@@]11C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]([H])(C5([H])[H])[C@]1([H])C3([H])[H])C([H])([H])[C@@]1([H])[C@]3([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]11C4=C(O[C@@]21[H])C(OC([H])([H])[H])=C([H])C([H])=C4C3([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(SC3=C2C([H])=C([H])C([H])=C3C#N)C(=O)N(C1=O)C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]1(O[H])C2=C(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])=C(Cl)C(Cl)=C2[H]
[H]N1C(=O)[C@@]2([H])N(C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])OC3=C(C([H])=C(Cl)C([H])=C3[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C2=C(N([H])C3=C([H])C([H])=C(O[H])C([H])=C3[H])C([H])=C3C(=O)N([H])C(=O)C3=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C1=C([H])C(=O)C(OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C([H])O1
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(Br)C([H])=C([H])S1)C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]N1[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C#N)C(=NC(SC([H])([H])C([H])([H])O[H])=C1C#N)N([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])=C(C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(\C([H])=C2/S\C(=N/C([H])(C([H])([H])[H])C([H])([H])[H])N(C2=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]ON([H])C(=O)C1(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C1=C(N([H])[H])N(N=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])N1C(=C(C(=O)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1[C@@]([H])(C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C3=C([H])C([H])=C([H])C([H])=C3C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C(N2C(=S)SC3=C(N=C(N=C23)C([H])([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(Br)=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C2C(=NC3=C1C([H])=C([H])C([H])=C3[H])C1=C([H])C([H])=C([H])C(=C1C2([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])[C@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(O[C@@]2([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])O[C@@]2([H])C([H])([H])N([H])C([H])([H])[H])C(=C1[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(O[H])C([H])([H])SC1=NC(=C(N1[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C2=NC3=C(SC4=C([H])C([H])=C(C([H])=C34)C3=C([H])C([H])=C([H])C([H])=C3[H])C(=O)N2[H])C([H])([H])C1([H])[H]
[H]N(\N=C1\C2=C(N([H])C3=C2C([H])=C(Cl)C([H])=C3[H])C(=O)N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])N(C([H])=C2C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N1C([H])=C(C#N)C2=C1N=C(SC([H])(C([H])([H])[H])C([H])([H])[H])N=C2C1=C([H])C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C(F)(F)C2([H])[H])=C(OC([H])([H])[H])C([H])=C1Cl
[H]C([H])([H])C1=NC(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])=C(C(=N1)C(=O)C1=C(C(=C(C(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(C(=O)N([H])C2=C([H])C(Br)=C(OC([H])([H])C3=C(Cl)C([H])=C([H])C([H])=C3F)C(Br)=C2[H])C([H])([H])SC1([H])[H]
[H]N(OC([H])([H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=C([H])C([H])=C(N=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
COC1=CC=C2C(CCCCN3C(C)(C)CCCC3(C)C)CCCC2=C1
[H]C1=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])SC(=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)N([H])C(=O)C(N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])SC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])(C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C2([H])[H]
[H]N([H])C(=O)C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(N1C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=O)[C@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N([H])C(=O)[C@@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])C1=NC(SC([H])([H])C2=C(F)C(F)=C([H])C([H])=C2[H])=NC2=C1SC(=N2)N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=N1)C(C1=C(C([H])=C(Cl)C([H])=C1[H])C([H])([H])C2([H])[H])=C1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(N([H])C2=C(F)C([H])=C([H])C([H])=C2C(=O)N([H])C([H])([H])[H])=C(Cl)C([H])=N1)C1=C([H])C([H])=C2C(=C1[H])N(C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N(C1=NC([H])=C([H])C(=C1[H])C1=NN([H])C(=S)N1C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(F)=C([H])C2=C1N(C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])[H]
[H]C1=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C(=C2OC(=C([H])C(=O)C2=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N(N=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=C([H])N3C(SC4=C([H])C(O[H])=C([H])C([H])=C34)=N2)C([H])([H])C([H])([H])C1([H])[H]
[H]N(N1C2=C([H])C([H])=C(Cl)C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C(=NC([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N(C3=C2N=C([H])C([H])=C3[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])C([H])([H])C1=O
CC(C)(O)C(=O)N[C@@H](CC1=CC=C(C=C1)C1=CC=CC=C1)C(=O)N1CCC[C@H]1C1=NC2=C(N1)C=C(F)C(F)=C2
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
[H]N([H])[C@]([H])(C1=NN=C(O1)SC([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)C1=C([H])C([H])=C(OC([H])([H])[C@]2([H])N([H])[C@]([H])(C(=O)N3C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C#N)C([H])([H])C2([H])[H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@]([H])(O[C@@]2([H])C([H])([H])N([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])[N@]2C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])OC([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C([H])C1=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
FC(F)(F)C1=CC=CC=C1C(=O)N1CCN(CC1)C1=NN=C(C=C1)C(=O)NCC1=CC=CC=N1
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])N(C(=O)C11C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=N1)C([H])([H])N1C(=O)N(C(=O)C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(SC(F)(F)F)C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])C([H])([H])N1C([H])=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])S(=O)(=O)C1=C([H])C([H])=C(N=C=S)C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C2C(=C1[H])C(=NC2([H])[H])C1=NC2=C(N1[H])C([H])=C([H])C(=C2[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C(C2=C(N=NS2)C([H])([H])[H])\C(=C(/[H])C2=C([H])N(C3=C([H])C([H])=C(C#N)C([H])=C23)C([H])([H])[H])C1=O
[H]N(C1=NC(=C([H])N2C1=NC([H])=C2C1=C([H])N([H])N=C1[H])C([H])([H])[H])C1=C([H])C(Cl)=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N([H])C2(C([H])([H])C2([H])[H])C1([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N(C(=O)C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C([H])C(F)=C(C([H])=C2[H])C2=NC3=C([H])C([H])=C(C([H])=C3S2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(Br)=C(N=C1OC([H])([H])[H])N([H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])[C@]([H])(N([H])[H])C([H])([H])C2=C(F)C([H])=C([H])C(F)=C2[H])C1([H])[H]
[H]N([H])C1=NC(=C([H])C(=N1)C1=C([H])C([H])=C(O1)C([H])([H])[H])C(=O)N([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)C1=C([H])C([H])=C(\N=C(/N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N(C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
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[H]OC(=O)C1=NN2C(=N1)C(O[H])=NC1=C([H])C(Cl)=C(Cl)C([H])=C21
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[H]OC1=C([H])C([H])=C(C([H])=C1F)C1=NO[C@@]([H])(C([H])([H])C(=O)OC([H])([H])[H])C1([H])[H]
CC1=NC(NC2CCCCC2)=CC(=C1)C1=CNC2=C1C=CC=N2
[H]C1=C([H])C2=C3C(=C([H])C([H])=C4C(=O)N(C(=O)C1=C34)C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N(C2=O)C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC(=NO2)C2=C([H])N(C3=C(Cl)C([H])=C([H])C([H])=C23)C([H])([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN([H])C2=C1C([H])=C(C([H])=C2[H])[N+]([O-])=O
[H]C1=C([H])C(N2C([H])([H])C([H])([H])N(C3=C([H])C(=O)OC4=C([H])C([H])=C(C([H])=C34)C([H])([H])[H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(O1)C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([C@]([H])(C([O-])=O)C([H])([H])C([H])([H])C([O-])=O)P([O-])(=O)O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])[C@]([H])([C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]23[H])C1([H])[H]
COC1=CC(=CC=C1OCCCNC(=O)NC1=CC=C(C=C1)C(F)(F)F)C1=C(NC2CCCCC2)N2C=C(Cl)C=CC2=N1
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[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C1=NOC(=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]OC(=O)C([H])([H])[C@]1(O[H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N=[N+]=[N-])C([H])=C2[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC(=C([H])S2)C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]2(O[C@@]([H])(OC2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]1([H])C(=O)O[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C2C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C(OC([H])([H])[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C2=C1[H]
[H]N(C1=NC2=C(N=NN2C2=C1SC([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
C1NCC(CC=C1)C1=CC2=C(O1)C=CC=C2
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)C1=C(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])N(N=C1C1=C([H])C([H])=C(C#CC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1OC1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C([H])([H])N([H])[H])C([H])([H])C([H])([H])C(O[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]C1=C(OC([H])([H])[H])C([H])=C(C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC(=O)[C@]1([H])N(C(=O)C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[C@]1([H])OC2=C(Cl)C([H])=C([H])C([H])=C2OC1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C2N=C(C([H])=C(C2=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1F
[H]N1C([H])([H])[C@@]2([H])N(C([H])([H])[C@]1([H])C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1N=NC(=N1)[C@@]([H])(C(=O)N([H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C(F)(F)F)C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C(OC([H])([H])[H])=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(N3C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])=C1[H]
[H]SC1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=C(C3=C([H])C(Br)=C([H])C([H])=C3N2[H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C1([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C(=O)[C@]([H])(N([H])C(=O)[C@]1([H])C([H])=C([H])[C@@]([H])(N2N1C(=O)[C@@](N([H])[H])(C2=O)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]N(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C1(C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C1=NC([H])=NC([H])=C1C#CC1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C(Cl)=C1[H]
[H]N([H])C1=NC2=C([H])C(C3=C4C([H])=C([H])N([H])C4=C([H])C([H])=C3OC([H])([H])C([H])([H])[H])=C(C([H])=C2C(=N1)N([H])[H])C([H])([H])[H]
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[H]O[C@]1([H])C2=C(N([H])C([H])=NC1([H])[H])N(C([H])=N2)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([O-])=O
[H]N(C(=O)C1=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C3=NSN=C23)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(OC(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]2([H])C3=C(C([H])=C(Br)C([H])=N3)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])=C([H])[N+]([O-])=C1[H]
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[H]ON([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])[N+]([O-])=O
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[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C([H])=C(OC3=NC4=C([H])C([H])=C([H])C([H])=C4O3)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]S\C(=N/N=C(/C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NN(C(OC([H])([H])C(=O)N2C([H])([H])C([H])([H])[C@@]([H])(O[H])C2([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[N+]([O-])=O)S(=O)(=O)N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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[H]C([H])=C([H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1N=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])SC(C(=O)N([H])C2=C(C([H])=C(Cl)C([H])=C2[H])C(=O)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1Cl
[H]N(C1=NC(OC([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]N(C(=O)N([H])C1=C([H])C2=C([H])N(N=C2C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC([H])=NN2C([H])=C([H])C(=C12)C([H])([H])OC1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
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[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(N2[H])C2=C(C3=C(C([H])=C(O[H])C([H])=C3[H])N2O[C@]2([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]2([H])O[H])C2=C1C(=O)N(N([H])C([H])(C([H])([H])O[H])C([H])([H])O[H])C2=O
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[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C([H])=C2[H])C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]OC(=O)[C@@]([H])(O[H])C1=C([H])C([H])=C([H])O1
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[H]N([C@]1([H])C(=O)N(C2=C([H])C([H])=C3C(=C2[H])C([H])([H])C([H])([H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C(Cl)C([H])=C([H])C2=C1[H]
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[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C2=C(C([H])=C([H])C(=C2[H])[N+]([O-])=O)N1C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C(=C1C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C(=C3[H])S(=O)(=O)C3([H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(C([H])([H])C(=O)N1[C@]([H])(C#N)C([H])([H])C([H])([H])[C@]1([H])C#N)C1(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])S[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON1C(=C([H])C2=C1C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C(N2C([H])([H])C([H])([H])N(C(=O)[C@]3([H])C([H])([H])N(C([H])([H])[C@@]3([H])C3=C([H])C(F)=C(F)C(F)=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(F)=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC([H])([H])C([H])([H])SC1=C(C#N)C(=C(C#N)C(=N1)N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
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[H]O[C@@]([H])([C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H])[C@]1([H])N([H])C([H])([H])[C@]([H])(OC2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
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[H]N([H])C1=NN([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])C(=NC(=N1)N([H])[H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C1=C(C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C(=C([H])C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[N+]([O-])=O)[C@@]([H])(C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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[H]N1N=C2N=C([H])N=C(C#CC3=C([H])N=C(C([H])=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C2=C1C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]N([H])C1=C(C#N)[C@@]([H])(C2=C([H])C([H])=C([H])O2)C(C#N)=C2S\C(=C(\[H])C3=C([H])C([H])=C([H])O3)C(=O)N12
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[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(SC3=C([H])C([H])=C(Cl)C([H])=C3[H])C3=C(N=C([H])C([H])=C3N2C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C(=O)N([H])S1(=O)=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C2N([H])C([H])=C(C2=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
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[H]N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12
[H]C1=C([H])C(C2=NN=C3SC([H])([H])C(=NN23)C2=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C2=NC(=N1)N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])(C([H])([H])C2=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])C1=NC(=C2N1C1=NC(OC([H])([H])[H])=C([H])C([H])=C1N=C2C([H])([H])[H])C(F)(F)F
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2S1)C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(C2=NC(=C3N2N=C([H])N=C3N([H])[H])C2=C([H])C([H])=C(C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C(F)=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C(=S)N(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C1=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]O[C@](C([H])([H])N1C([H])=C(N=C1C([H])([H])[H])C([H])([H])[H])(C([H])([H])C(C1=C(OC([H])([H])[H])C([H])=C([H])C(F)=C1[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])[C@]2([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(S2)C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C([H])O1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OP(=O)(O[H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C#CC1=C([H])C([H])=C(F)C([H])=C1F
COC(=O)C1=CC=C(COC2=CC=C(\C=C\C(\C)=N\NC(N)=S)C=C2)C=C1
[H]\C(C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])=C1\C([H])([H])N2[C@]3([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]1([H])C3([H])[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(OC2=C(C([H])=C([H])C(=C2[H])[N+]([O-])=O)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C(=O)C1=C([H])C([H])=C(C(=C1[H])S(=O)(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=NC([H])([H])C([H])([H])C2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C2([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C(C(=O)N([H])C2=C([H])C([H])=C(C(Cl)=C2[H])C2=C([H])C([H])=C([H])C(OC(F)(F)F)=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])=C([H])C2=C(N(C(=N2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])C2=NN([H])N=N2)C1=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C([H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C#N
[H]C1=C(SC(=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2S1)C(=O)O[C@@]1([H])C(=O)OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(C2=NC3=C(S2)N=C([H])C([H])=C3[H])=C1C([H])([H])[H]
[H]N(C1=C([H])C(Br)=C(SC2=NC([H])=C([H])N2C([H])([H])[H])C([H])=C1[H])C1=C(C#N)C([H])=NC2=C1C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])=C2[H]
[H]N(\C(=N/C([H])([H])C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]\C(=C(\C(=O)O[C@]1([H])C2=C(O[C@]1([H])C(OC(=O)C(=C(\[H])C([H])([H])[H])\C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C1=C2OC(=O)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C#CC1=C(SC2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
OB1OCC2=CC=C(NC3=CC=CC=C3)C=C12
[H]O[C@@](C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)(C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NN(C2=NC(=O)N(C(=O)C2=N1)C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2OC1([H])[H])[N+]([O-])=O
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])OC3([H])[H])=C2C([H])=NN(C2=N1)C([H])([H])C(F)(F)F)C1=C([H])C([H])=C([H])N=C1[H]
[H]O\N=C(/[H])C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)N([H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=N1)C1=C(ON=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])SC(=N1)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])[H]
[H]N([H])C1(C2=C([H])C3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H]
CC[C@@H](NC1=NC(NCC2=C(O)C=CC(F)=C2)=C2N=CN(C(C)C)C2=N1)C(C)O
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=NS2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C#CC2=C([H])C([H])=C([H])C(N([H])[H])=C2[H])C([H])=C1[H]
[H]N=C(SC([H])([H])C([H])([H])[H])N([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])C1=C2N=C([H])N=C2N(C([H])=N1)C([H])([H])[C@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C2=C([H])C3=C(O[C@@]2([H])C1([H])[H])C([H])=C(OC3=O)C([H])([H])[H]
[H]N(C([H])=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])=C(C2=C1N=C([H])C([H])=C2[H])C1=C(C(=O)N([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C(=O)C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])[C@]3([H])N4C5=C(SC([H])([H])C([H])([H])C4([H])[H])C([H])=C([H])C([H])=C5[C@]3([H])C2([H])[H])C(N([H])[H])=C1[H]
O=C1\C(CNC\C1=C/C1=NC=CC=C1)=C\C1=CC=CC=N1
[H]OC1=NC(=NC2=C1C(F)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=NC2=C(C([H])=C([H])C([H])=C2[H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C(SC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C(N([H])C(=O)N([H])C2=C([H])C(OC([H])([H])[H])=C(C([H])=C2[H])C2=C([H])N=C([H])O2)=C([H])C([H])=C1[H]
NC(=O)C1=C(NC(=C1)C1=CC=NC=C1)C1=CC(F)=CC=C1
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C(N([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[C@@]3([H])OC4=C(C([H])=C([H])C([H])=C4[H])N(C([H])([H])[H])C3([H])[H])C([H])=C2C([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)N([H])[C@@]1([H])[C@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N1N=C(N(\N=C(/[H])C2=C([H])C([H])=C(OC([H])(F)F)C([H])=C2[H])C1=S)C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=NC2=C(C([H])=C([H])C([H])=C2N1[H])C(=O)N([H])[H]
[H]OC(=O)C(=O)N([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SN=N1)S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C(=O)O[H])C([H])=C1[H])C(=O)O[H]
[H]N(C(=O)C1=C([H])N=C([H])C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]C1=C([H])C(F)=C(C(F)=C1[H])C([H])([H])N1C(=O)N(C(=O)C2=C1C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN([H])C([H])=C1[H]
OB(O)C1=CC(NS(=O)(=O)C2=CC(=CS2)S(=O)(=O)C2=CC=CC=C2)=CC=C1
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N=C(C1=C([H])C([H])=C([H])S1)C([H])([H])C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])C1=C([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(O[H])C([H])([H])N(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=S)N1N=C(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(OC([H])([H])C([H])([H])[H])=C1[H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1Br)C([H])([H])C([H])([H])C(=O)N([H])[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])=C(Br)C(=O)N2C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1[C@]2([H])C3=C(N(C4=C([H])C([H])=C(C([H])=C34)S(=O)(=O)C3=NN(C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]OC(=O)C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C(=C(C4=C([H])C([H])=C([H])C([H])=C4[H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])=C([H])C([H])=C2O1
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C(OC([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C1[H])=C(N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C2=C(N=C(N2[H])C2=C([H])C([H])=C([H])N2C([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])[H])[C@@]1(C([H])([H])[H])C([H])([H])N(C2=NC([H])=NC3=C2OC2=C([H])C([H])=C(Cl)C([H])=C32)C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(S1)C([H])([H])C([H])([H])C(=O)N([H])C1=NC([H])([H])C([H])([H])C([H])([H])N1[H]
[H]N(C(=O)C1=C([H])C(=NN1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])[H]
CN1C(=CC2=C1C(=O)N(C)C(=O)N2C)N1C=C(N=N1)C1=CC=C(Cl)C=C1
[H]C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C2N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])[C@]1(C([H])=C(C2=C([H])C(F)=C([H])C([H])=C2F)C([H])([H])N1C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])N([H])C(=O)C1=C(N(C(=N1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])S[C@@](N2C([H])=NC3=C2N=C(Cl)N=C3N([H])C([H])([H])C2=C([H])C([H])=C([H])C(I)=C2[H])(C(=O)N([H])C([H])([H])[H])[C@@]1([H])O[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(\[H])=C(\[H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C(C2=C(N([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C1=C2C([H])=C(SC2=NC([H])=C1C#N)C(\[H])=C(/[H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(ON=C1C([H])([H])[H])N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C(F)(F)F
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[P@@](=O)(OC([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])S1
[H]OC(=O)[C@@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(C(=O)OC([H])([H])[H])C(O[H])=C([H])C([H])=C1[H])C(=O)N([H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)C(=C(/[H])C1=C([H])N=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])\C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])S1
[H]N(C1=NC2=C(N=NN2C2=C1SC([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=CC=C(C)C(=C1)C(=O)CCCN1CCC(O)(CC1)C1=CC=C(Cl)C=C1
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C1=NC2=C(N=C(N=C2O[H])N([H])[H])C([H])=C1[H])C(=O)O[H]
[H]OC(=O)[C@]([H])(OC1=C(C2=C(C([H])=C1C([H])([H])C([H])([H])C([H])([H])[H])C(=NO2)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])SC1=C([H])C(=NC2=C(C(=NN12)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])N=C(C2=NC([H])=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N(C1=O)C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C(C([H])=C1[H])C1=C([H])OC([H])=C1[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=NC2=C([H])C3=C(C([H])=C2S1)C(=O)[C@@]1([H])N(C([H])([H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[C@@]32C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1N=NC2=C([H])C([H])=C(Br)C([H])=C2C1=O
[H]OC(C1=C([H])N=C(S1)N(C(=O)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])(C(F)(F)F)C(F)(F)F
[H]O[C@@]([H])(C([H])([H])OC1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])=C([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2=O)C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C(N=C(O1)C1=C2C([H])=C([H])C(=NC2=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)N(C2=NC([H])=C([H])N2C([H])([H])[H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1Cl)C(F)(F)F
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(=O)(=O)O[C@@]1([H])C([H])([H])N([C@]([H])(C(=O)OC([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NN2C(=NC3=C(C2=O)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])\C1=N\N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(O[H])C(=C1[H])C([H])([H])N([H])C1=C([H])C([H])=C(O[H])C(=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C(SC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C([H])C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C12)C(=O)N1C([H])([H])C([H])([H])C([H])([H])C(F)(F)C1([H])[H]
[H]N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(OC1=NC(=C([H])C(C#N)=C1[H])C1=C(C#N)C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]O[C@]([H])(C(\[H])=C(/[H])[C@@]1([H])[C@]([H])(O[H])C([H])([H])[C@]([H])(O[H])[C@]1([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])P(=O)(O[H])O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]2(C3=C(C([H])=C([H])C([H])=C3[H])[S@+]([O-])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
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[H]N1C2=C([H])C(Cl)=C([H])C(Cl)=C2C(=O)[C@@](C1=O)(C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])[C@]([H])(F)C([H])([H])N2[H])=C([H])C(O[H])=C1[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1O[H]
[H]N([H])C(=O)C1=C([H])C2=C(C([H])=C3N2C([H])([H])C([H])([H])C([H])([H])N([H])C3=O)C([H])=C1[H]
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[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C(F)=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C(N([H])C(=O)C([H])=C2[H])C1=O)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]N1N(C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C([H])([H])C1=C([H])C([H])=NC(=C1[H])C(=O)N([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])[H])C1=C([H])C2=C(OC(F)(F)O2)C([H])=C1[H]
[H]N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C3N(N=C([H])N=C3N([H])C3=C([H])C4=C(C([H])=C3[H])N(N=C4[H])C([H])([H])C3=C([H])N=C([H])C(=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C(N([H])[H])C([H])=C1C([H])([H])C([H])([H])N([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=NC2=C([H])C([H])=C([H])C([H])=C12)C(=O)N(C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[C@@]1([H])C([H])([H])N2C([H])=C([H])N=C2C1([H])[H]
[H]OC(=O)C1=C(C(=O)O[H])[C@@]([H])(C2=C(Cl)C([H])=C([H])C([H])=C2[H])C(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])=C(N1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H]
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[H]N(C(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(C#CC3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1[H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]O[C@]([H])(C([H])([H])N([H])S(=O)(=O)C1=C(C(=C(OC([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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COC1=CC2=NC=NC(NC3=CC(Cl)=C(F)C=C3)=C2C=C1OCCO
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[H]OP(=O)(O[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1P(=O)(O[H])O[H]
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[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1Br)C([H])([H])C1=C([H])C([H])=C([H])S1
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Cl.C=CCCN1CCC2(CCCC3=CC=CC=C23)CC1
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[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H]
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[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]N(C(=O)C1=C2N=C([H])C([H])=C([H])N2N=C1[H])C1=C([H])N(N=C1C1=C(C([H])=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])OC2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(OC3=C(O[H])C([H])=C([H])C(=C3[H])C1([H])[H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]1([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N(C1=O)[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])N([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C2=NSN=C12)C(\C([O-])=O)=C(\C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C1=C(C([H])=C([H])C(Cl)=N1)C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])N(C3=NC([H])=C(N=C3C([H])([H])[H])C(=O)N([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(SC([H])([H])C2=NN=C3C([H])=C([H])C(=NN23)C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]C1=C2C(=C([H])C(=C1[H])C([H])([H])[H])N(C(=O)C2([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2C2=NN(C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(C2=NN=C(N2C([H])([H])[H])[C@@]23C([H])([H])C([H])([H])[C@@](C([H])([H])C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])(C([H])([H])C2([H])[H])C([H])([H])C3([H])[H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C(SC2=C1C(=NC([H])([H])C1=NN=C(N21)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C#CC([H])([H])N1C(=O)[C@]2(C3=C(C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H]
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[H]N([H])C1=NC([H])=NN2C(=NC(=C12)C1=C([H])C2=C(C([H])=C([H])C(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])[C@]1([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
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[H]N(C(=O)N1C([H])([H])C([H])([H])N(\C(=N\C#N)N([H])C2=C3C([H])=C([H])C([H])=NC3=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]N(C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NN(C([H])=C1[H])C([H])([H])C([H])([H])C#N)[C@@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(OC2=C([H])C(Cl)=C(C#N)C([H])=C2[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C([H])=C(C2=C1[H])C1=C([H])C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C(C(=O)C2=C(O1)C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]C1=C(SC2=C1C(=NC([H])([H])C1=NN=C(N21)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C#CC1=NC([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC([H])=NC2=NN(C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])[C@]1([H])SC([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C([H])=C([H])N2N=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
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[H]N(C1=C2C([H])=C([H])C([H])=C([H])C2=C(N=N1)C1=C([H])C([H])=C([H])C2=C([H])N=C([H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N([C@]1([H])C(=O)N(C([H])([H])C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C(Cl)S1
[H]N(C1=NC([H])=NC2=C1SC1=C2C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=C(/[H])C([H])([H])C1=C(O[H])C(Cl)=C(C(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])\C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C3C(=N2)N([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2=O)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])OC2=C(C(OC([H])([H])[H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C2=C(Cl)C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])O[H]
COC1=CC=C2N(C(=O)C3=CC=C(Cl)C=C3)C(CCC(=O)NS(=O)(=O)C3=CC=C4C=CC=CC4=C3)=C(C)C2=C1
NC(C1=CC=CC(Cl)=C1)C1=NC2=CC=C(C=C2C(=O)N1)C1=CNN=C1
[H]OC1([H])C([H])([H])C([H])([H])N(C2=NC(=C(C([H])=C2C#N)C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])O[C@@]([H])(C2=C([H])N=C([H])N2C([H])([H])[H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(OC([H])([H])[H])C(=O)C1=C([H])C([H])=C(C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)N([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C(=C23)C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C1=C(OC([H])([H])[H])N=C(OC([H])([H])[H])C([H])=C1[H])N([H])C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C(=NC2=C([H])C([H])=C(C([H])=C12)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C(N(N=N1)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1SC([H])([H])[H])C1=C2C3=C(C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])OC1=O
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])=NC2=C1C([H])=C([H])C([H])=C2[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])N(C(=O)N([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(N([H])C2=C3N=NN(C3=NC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C(=O)N([H])C(C1=O)(C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)N(C([H])([H])[H])C([H])([H])[H])C(SC([H])([H])[H])=N1
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N1C(=O)C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N([H])[C@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])C(=O)C1=C(N([H])[H])C2=C(S1)N=C(C([H])=C2C([H])([H])C([H])([H])C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(C(=O)OC([H])([H])N2C(=O)C3=C(C([H])=C(C([H])=C3S2(=O)=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])C#N)C([H])([H])C1([H])[H]
[H]O[C@@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])N(C(=O)[C@@]2([H])C([H])([H])N(C3=NC([H])=C([H])C([H])=C3[H])C([H])([H])[C@]2([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C([H])C2=C1OC(=N2)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
OB(O)C1=CC=C(F)C=C1
[H]N(C([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=N[H])N([H])[H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=C2N([H])C([H])=C(C2=C1[H])C1=C([H])C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2F)C(F)(F)F)=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C2=C(C([H])=C(N=C12)C([H])([H])[H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C([H])C(=C([H])N2C([H])=C1C1=C([H])C([H])=C([H])C(Cl)=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(SC([H])([H])C(=O)N2C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])C2([H])[H])=C1C([H])([H])[H]
[H]C1=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C(=N1)C#CC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(\[H])=C(\C(\[H])=C(/[H])\C(\[H])=C(/C1=C([H])C(=C([H])C(=C1OC([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])/C([H])([H])[H]
[H]N=C(OC([H])([H])[H])N([H])S(=O)(=O)C1=C(F)C(F)=C(F)C(F)=C1F
[H]N([H])[C@]([H])(C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(\C([H])=C1/C(=O)N([H])C(=O)C2=C([H])C([H])=C(C([H])=C12)C1=C([H])OC([H])=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])=O)C1=C([H])C([H])=C([H])C2=C1C(=O)C1=C(N([H])N=C21)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(SC([H])([H])C2=C([H])C(\C([H])=C(/C#N)C(=O)N([H])[H])=C([H])C(OC([H])([H])C([H])([H])[H])=C2O[H])C([H])=C1[H]
[H]N1N=C(C2=C1C1=C([H])C([H])=C([H])C([H])=C1O2)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(N=C3N(N(C(=O)C3=C2C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]N([C@]1([H])C(=O)N(C2=C(F)C3=C(C([H])=C2[H])C([H])([H])N([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)S1
[H]N(C(=O)C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C2C3=C4C(C([H])=C([H])C([H])=C4C(=O)C2=C1[H])=C([H])C([H])=N3
[H]O[C@]([H])([C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])[C@]([H])(OC([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])[C@]([H])(OC([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])OC(=O)N(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N(N1C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])=C(Cl)C([H])=C2[H])C(=O)C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C(=O)N([H])N1C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])=C(Cl)C([H])=C2[H]
[H]N(C1=C2C([H])=C([H])C(OC([H])([H])[H])=C([H])C2=NC([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]([H])(N([H])C1=NC2=C(N([H])C([H])([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C([H])C(Br)=C([H])C([H])=C12)N1C([H])([H])C([H])([H])C2(OC(=O)N(C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])OC2=C(C(OC([H])([H])C([H])([H])C([H])([H])OC3=C(C(OC([H])([H])[H])=C(C([H])=C3[H])C3=C([H])SC(SC([H])([H])[H])=N3)C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C(C([H])=C(OC([H])([H])C([H])([H])SC([H])([H])[H])C([H])=C1[H])C([O-])=O
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C([H])N=C1[H])C1=C([H])C([H])=C2N([H])N=C(Cl)C2=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1N=C(C(=O)OC([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C(C(=NO1)C([H])([H])[H])S(=O)(=O)N1C([H])([H])C2=C(N(C(=N2)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C(O\C1=C1/C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)SC([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])N(C([H])=C2C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N1C(=O)C2=C(C1=O)C1=C(C3=C2C2=C([H])C([H])=C([H])C([H])=C2N3[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
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[H]N1C([H])([H])C([H])([H])C([H])([H])[C@]2(OC([H])([H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1OC(=O)C(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=C([H])C(=O)O2)C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C(C([H])=C([H])C(Cl)=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N([H])C(\C([H])=C2/C(=O)N([H])C3=C([H])C([H])=C(F)C([H])=C23)=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N(C([H])([H])[H])C(C3=C([H])C([H])=C([H])C([H])=C3[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C3C(ON=C3C3=C([H])C([H])=C([H])C([H])=C3[H])=C2C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])N(C([H])([H])C1=C3C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C3=NC([H])=C1[H])C2([H])[H])C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]N1C([H])=C(C2=C(OC([H])([H])[H])C([H])=C([H])N=C12)C1=NC(SC([H])([H])[H])=NC([H])=C1[H]
[H]N([H])C1=C([H])C(F)=C([H])C([H])=C1N([H])C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C(N=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
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[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(C1=C([H])N=C(S1)C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]N(\C(=N\C#N)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O
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[H]N(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)N=C1[H]
[H]OC(=O)[C@]1(N([H])C(=O)[C@@](N([H])C(=O)O[C@@]2([H])[C@@]3([H])C([H])([H])[C@]4([H])C([H])([H])[C@]([H])(C3([H])[H])C([H])([H])[C@@]2([H])C4([H])[H])(C([H])([H])[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C([O-])=O)C1=NC(=C(S1)N1N=C([H])N=C1[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
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[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N([H])C2=C([H])C(Cl)=NC(Cl)=C2[H])=C([H])N=C1[H]
[H]N([H])C(C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC([H])=C1C#N)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])=C([H])N=C1C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
CN1C(SCCCN[C@@H]2CC[C@@]3(CC23)C2=CC=C(C=C2)C(F)(F)F)=NN=C1C1=C(C)N=CO1
[H]N1C([H])([H])[C@]2([H])C([H])([H])[C@]2(C2=C([H])C([H])=C3OC([H])([H])C([H])([H])C3=C2[H])C1([H])[H]
CCC1=C(C=CC=C1CCCC(O)=O)C1=NSC(=N1)C1=CC=C(C2=CC=CC=C2)C(=C1)C(F)(F)F
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[H]OC1=C2N([H])C(=O)C([H])=C([H])C2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(=C([H])C([H])=C2[H])N(C(=O)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(OC(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C1=NC(C2=C([H])N=C3C([H])=C([H])C([H])=C([H])N23)=C(C#N)C([H])=N1)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1([H])C([H])([H])N(C2=C(C(=NC(=N2)C2([H])C([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C1([H])[H]
[H]OC1=C(F)C([H])=C2C(=C1[H])C([H])([H])[C@@]([H])(N([H])[H])[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(Br)C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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COC1=CC2=C(CN(C[C@]3(NC(=O)NC3=O)C#CC3=C(O)N=C(C)N=C3)C2=O)C=C1
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[H]C1=NC([H])=C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N=C1O[C@@]1([H])C([H])([H])[N@@]2C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
O=C(CCCCC1CCSS1)OC1CCN(CC2=CC=CC=C2)CC1
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[H]ON(C(=O)N([H])[H])[C@]1([H])C2=C([H])C3=C([H])C(Cl)=C([H])C([H])=C3N2C([H])([H])C1([H])[H]
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[H]OC([H])([H])C#CC1=C([H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]OC(=O)C(=O)N([H])C1=C(SC(=C1[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)O[H])C([H])=C1[H])C(=O)O[H]
[H]OC(=O)C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])=C(C2=C([H])C([H])=C(F)C([H])=C2C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2C([H])([H])[H])C1([H])[H]
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[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])\N=C2/C(=O)N([H])C3=C([H])C([H])=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C23)C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
ClC1=C(Cl)C=C(C=C1)[C@H]1CNCC=CC1
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[H]C1=C([H])C([H])=C(O1)C1=C([H])C(=O)C([H])([H])C2(O1)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
NC1=NC(O)=CC(=N1)C1=CC(C#N)=C(OCC2=CC=C(F)C=C2)C=C1
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[H]N(C1=NC2=C(N=NN2C2=C1C([H])=C([H])C([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C#N)C2=C1N=C(SC([H])([H])[H])N=C2C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC([H])([H])[H]
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[H]N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C1=C(N([H])C([H])([H])C2([H])[H])C([H])=C([H])C([H])=C1[H]
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[H]N(C1=C2C(=NC3=C(C(=NN13)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[C@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(\C(=N/C(=O)C([H])([H])[H])N([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(C1=O)C1=C(N3C4=C1C([H])=C([H])C([H])=C4C([H])([H])C([H])([H])C3([H])[H])C1=C2C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
CN1CCN(CC1)C1CC2=C(SC3=C1C=C(CN)C=C3)C=CC=C2
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C(=O)OC([H])([H])[H])C([H])=C1[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(Br)=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H]
[H]O[C@]1([H])C([H])=C([H])[C@]([H])(O[C@@]2(N(C(=O)C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H])C(=O)C1=NC([H])=C([H])S1
[H]C1=C(C2=C([H])C([H])=C([H])C([H])=C2N1[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]C1=C(C#N)N(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1N=NN=C1C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C(N(C(=O)C([H])([H])[H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C(=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])N(C([H])([H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N1[H]
[H]N1C([H])=C(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C(=NC3=C2C([H])=C([H])N=C3[H])C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C12)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])([N+]([H])([H])[H])[C@@]([H])(O[H])C([H])([H])C(\[H])=C(/[H])[C@]([H])(O[H])[C@]([H])(C(=O)OC([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=NO[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C1([H])[H]
[H]\C(=C(\[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1([H])N([H])C(=S)N([H])C2=C([H])C([H])=C(C([H])=C12)C([H])([H])[H]
CS(=O)(=O)C1=CN=C(C=C1)[C@H]1CC[C@@H](CC1)OCC1CCN(CC1)C1=NC=C(C=N1)C(F)(F)F
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C(=C1[H])C1=C([H])C(=NC([H])=C1[H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C(F)C([H])=C1[H])C1=C([H])C(=C(C#N)C(=N1)N([H])[H])C1=C([H])C(N([H])C(=O)[C@]([H])(O[H])C([H])([H])C([H])([H])C([O-])=O)=C([H])C([H])=C1[H]
[H]N1C2=C(C([H])=C(Cl)C([H])=C2[H])C2=C1C([H])([H])[C@@]([H])(C([H])([H])C2([H])[H])[C@](C(=O)OC([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])N1C(=NC(=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(F)(F)F
[H]N(C1=NC(=NC([H])=C1[H])N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=NC([H])([H])C2=C1C([H])([H])N(C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C1=C2C([H])=C(SC2=NC([H])=N1)C([H])([H])[H]
[H]N([H])C1=C(C([H])=C(C([H])=N1)C1=C([H])N(N=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=NC2=C(O1)C(=C([H])C([H])=C2[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NO[C@@](C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])(C([H])([H])C(=O)OC([H])([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C([H])([H])C1=C([H])C(O[H])=C(O[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(SC3=C([H])C([H])=C(Cl)C([H])=C3[H])C3=C(C([H])=C([H])N=C3N2C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(SC([H])=C2[H])C(=N1)C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(OC2=C(N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C(C([H])=C2[H])C(=O)N([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])OC1=C(OC([H])([H])C([H])([H])[H])C([H])=C(\C([H])=C(/C#N)C(=O)N([H])C([H])([H])[C@@]2([H])OC([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(O[H])C(O[H])=C2[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=NN2[C@@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C(C2=NC3=C(C([H])=C([H])C(=C3[H])C(=O)OC([H])([H])[H])N2C([H])([H])[H])=C1C([H])([H])[H]
[H]N(C1=NC(=NC2=C1N([H])C([H])([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])O1)C1=NC2=C([H])C([H])=C([H])C([H])=C2S1
CN1C=C(C=N1)C1=CC(NC2=CC=C(OC(F)(F)F)C=C2)=NC=N1
[H]N([H])C(=O)C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(O1)C([H])([H])[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C([H])C(=C([H])N=C1N([H])C1=C([H])N=C(OC([H])([H])[H])N=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C(N=C=S)C([H])=C3[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(S1)C([H])([H])C([H])([H])C(=O)N([H])C1=NC([H])([H])C([H])([H])C([H])([H])N1[H]
[H]N(C1=C([H])C([H])=C([H])C(Br)=C1[H])C1=NC([H])=NC2=C1N=C(N=C2[H])N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(I)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]O[C@]([H])(C1=C([H])C2=C([H])N=C(N=C2N1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])C1=C([H])N(C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])N3C(=O)N4C([H])([H])C([H])([H])C([H])([H])[C@@]4([H])C3=O)C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N([H])C1=NN([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])C(=NC(=N1)N([H])[H])N1C([H])([H])[C@]([H])(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(S1)C([H])([H])C([H])([H])C(=O)N([H])C1=NC([H])([H])C([H])([H])C([H])([H])N1[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C([H])C([H])=C1[H]
[H]O[C@]1([H])[C@]([H])(O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])[C@@]2([H])C([H])([H])OC([H])([H])C2([H])[H])[C@@]1(O[H])C([H])([H])[H])C([H])([H])OC(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=NN(\C(S1)=N/S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C(=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(OC([H])([H])[H])C(F)=C([H])C(C2=C3N=C(N=C(N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C1Cl
[H]OP(=O)(O[H])C(F)(F)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)P(=O)(O[H])O[H])C([H])=C1[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])OC1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C(=O)N1C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2C([H])([H])C1([H])[H]
[H]OC1=NC2=C(N=C1O[H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2S1
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[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1([H])C([H])=C(C2=C([H])C(F)=C([H])C([H])=C2F)C([H])([H])N1C(=O)[C@@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(C#N)=C([H])C(=C2O1)C([H])([H])[H]
[H]N(C(=O)C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])=C1[H]
[H]N1C(=NC2=C1C([H])=C(F)C(F)=C2[H])N1C([H])([H])C([H])([H])C2(OC(=O)C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[H])[C@]([H])(N2C([H])=NC3=C(N=C(N=C23)N([H])C([H])([H])C([H])([H])C2=C([H])N(C([H])=N2)C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])N([H])C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1F)C1=NC2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(SC([H])([H])[C@]([H])(N([H])C1=O)C(=O)O[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])\C(=N/N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])[C@]2([H])N(C3=C([H])C(=C([H])C([H])=C3C2([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
CC1=C(Cl)C(C)=C2C(N)=C(SC2=N1)C(=O)NCCC1=CC=CC=N1
[H]N1C([H])([H])C([H])([H])C([H])(N2C([H])=NC(=C2C2=C([H])C([H])=NC(OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])=N2)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C([H])=C2[H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C(=O)C1=C([H])C([H])=C(C2=NN=C(N2C([H])([H])[H])[C@]23C([H])([H])C([H])([H])[C@](C4=NC(=NO4)C4=C([H])C([H])=C(F)C([H])=C4[H])(C([H])([H])C2([H])[H])C([H])([H])C3([H])[H])C(Cl)=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N(C(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(=N1)N1C([H])([H])C([H])([H])C([H])(C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])OC3=C([H])C([H])=C([H])C([H])=C3OC2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])N([H])[C@]([H])(C1=C([H])C(F)=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]C1=C(SC(=N1)[C@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NN([H])C2=C([H])C(=C([H])C([H])=C12)C1=C([H])C([H])=NC([H])=N1
CN1C(\C=C\C2=CC=C(C=C2)C(C)=O)=CC2=C1C(=O)N(C)C(=O)N2C
[H]O[C@]([H])(C([H])([H])N1N=C2N=C([H])N=C(N([H])[H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(=C(C#CC([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(=N1)N([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])C(=O)N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])N(C(=O)C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])[H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C(\C#N)C(=O)N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N=C(N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])[H])C([H])([H])F
[H]N(C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@](C([H])([H])C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])(C([H])([H])C(C1=C2OC([H])([H])C([H])([H])C2=C([H])C(F)=C1[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C1=C(N(C2=C([H])C([H])=C(OC([H])([H])C([H])=C([H])[H])C([H])=C2C1=O)C([H])([H])C1=C(C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C([H])([H])[H])C(=O)O[H]
[H]N1C(=O)C([H])([H])N(C(=O)C2=C(N3C(S2)=N[C@@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]3([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C1=C([H])C2=C(N([H])C([H])=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1N=C([H])C([H])=C2[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]1([H])C([H])([H])C([H])([H])[C@@](N([H])[H])(C(=O)O[H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=S)C([H])([H])[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@](OP(=O)(O[H])O[H])(N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@@](=O)(O[H])OP(=O)(O[H])O[H])[C@@]1([H])O[H])N1C([H])=C(F)C(=O)N([H])C1=O
[H]N(C1=C([H])C(Cl)=C(F)C([H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])C([H])=C(N([H])C([H])([H])C3=C(N=C([H])N3C([H])([H])[H])C([H])([H])[H])C([H])=C12
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])N2C(=O)N([H])C3=C(N(N=C3C(F)(F)F)C3=C([H])C4=C(ON=C4N([H])[H])C([H])=C3[H])C2=O)C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C(C(=O)N1C([H])([H])[H])C1=C([H])C(F)=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C([H])=C([H])C([H])([H])[C@]1([H])[C@]2([H])C3=C(C(=NN3[H])C3=NN=NN3[H])C([H])([H])[C@]12[H]
[H]N(C(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C2C([H])=C([H])N(C(=O)C2=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
CCCCN1C(C)=C(C)C=C(NC(=O)C2=C(F)C=CC=C2)C1=O
[H]O[C@]1([H])C2=C([H])C([H])=C(N([H])C(=O)C3=C([H])C4=C(N3[H])C([H])=C([H])C(Cl)=C4[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N1\C(SC([H])=C1C([H])([H])[H])=C(\C#N)C1=C2C([H])=C(F)C([H])=C([H])C2=NC1=O
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C(=O)C3=C([H])C([H])=C(F)C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=NC(=C(C(=O)OC([H])([H])[H])C2=C([H])C([H])=C3N=C(N([H])C4=C(Cl)C([H])=C([H])C([H])=C4Cl)N(C3=C12)C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(C1=O)C1=C(C3=C2C2=C([H])C(=C([H])C([H])=C2N3[H])C(=O)C([H])([H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@](=O)(O[H])O[P@](=O)(O[H])C(Cl)(Cl)P(=O)(O[H])O[H])[C@@]1([H])O[H])N1C([H])=C([H])C(=O)N(C1=O)C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=NC(=C(N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NN(C2=C1C([H])([H])[C@@]1(C(=C2[H])C([H])([H])C([H])([H])N(C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(N=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])S(=O)(=O)C2=C(C([H])=C(C([H])=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C2N(C(=O)C([H])([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]OC1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C(C([H])=NC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1O[H])C1=C([H])C([H])=C(S1)C(\[H])=C1/SC(=O)N(C1=O)C([H])([H])C([H])([H])C(=O)O[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC([H])([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])[H]
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[H]\C(=C(\[H])C1=C([H])C(OC([H])([H])[C@@]2([H])N([11C]([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])=C([H])N=C1Cl)C1=C([H])C([H])=NC([H])=C1[H]
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[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])SC2=C([H])C([H])=C([H])C([H])=C2C1=O)[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C(=NN1C([H])([H])C(F)(F)F)C1=C([H])C([H])=C(OC([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=N2)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])N(C([H])([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C2=NC([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)C1=NN=C(O1)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
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[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=C3C(=NC([H])=N2)N([H])C([H])=C13
[H]N([H])C1=C(Br)C([H])=C(C([H])=C1F)S(=O)(=O)N([H])[H]
[H]N=C1N([H])[C@](C(=O)N1C([H])([H])[H])(C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=C([H])C(C#N)=C1[H])C1([H])C([H])([H])C1([H])[H]
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[H]O[C@]1(\C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])=C1\C(=O)N([H])C2=C([H])C([H])=C(C([H])=C12)S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])=C([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C([H])=C([H])C([H])=C([H])C2=NC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C(N=C(S1)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])N(C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]OC1=C2C(=NC3=C1C([H])=C([H])C([H])=C3[H])N(N=C2C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C2=C(C(F)=C([H])C([H])=C2[H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]C1=C([H])N(N=N1)C1=C([H])C([H])([H])[C@]2([H])[C@]3([H])C([H])([H])C([H])([H])C4=C([H])C(=O)C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
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[H]OC1=C(C(OC([H])([H])C2=C([H])C([H])=C(\C([H])=C3/SC(=S)N([H])C3=O)C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N=C(SC([H])([H])C([H])([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=NC(=C(S1)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N1C(=O)N(C2=C(N(C(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])Cl)C1=O)C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])OP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=S)[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N([H])[H])N([H])C2=O
[H]N1C2=C(C([H])=C([H])C(=C2[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C1=O
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])N([H])C(=O)C([H])(N([H])C(=O)C([H])(N(C(=O)C([H])(N([H])C(=O)C2([H])N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])[H])C([H])([H])SSC([H])([H])C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C2([H])[H])C([H])([H])O[H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(O[H])C([H])([H])[H]
[H]OC(=O)[C@]12O[C@@](O[C@]([H])(C3=NN=C(O3)N([H])C([H])([H])[H])[C@@]1(O[H])C(=O)O[H])(C([H])([H])C([H])([H])C(=C([H])[H])[C@@]([H])(C(=O)C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(O[H])[C@@]2([H])O[H]
[H]\C(C1=C([H])C(=NO1)C1=C([H])C([H])=C(C#N)C([H])=C1[H])=C1/C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=N2)N2C(=O)C3=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C(F)=C([H])C([H])=C1F
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@@]([H])(C([H])([H])C([H])([H])C2=C(C([H])=C(N=C2C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(F)(F)F)C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])O[H]
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1C(=O)OC([H])([H])C([H])([H])[H]
[H]O[C@]1([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C#N)N1C([H])([H])[H]
[H]OC1=C([H])C2=C(OC(=O)C([H])=C2C([H])([H])N([H])C2=C([H])C([H])=C([H])C([H])=C2F)C([H])=C1C([H])([H])[H]
[H]N([H])C1=C(\C([H])=N\OC([H])(C([H])([H])[H])C([H])([H])[H])C(=NC([H])=N1)N([H])C1=C([H])C([H])=C2N(N=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])C2=C(OC([H])([H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C#N)C1=C(C([H])=C([H])N=C1N([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)[C@@]([H])(C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])N=C1C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@]([H])(C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1OC([H])([H])C([H])([H])N1N=C([H])C([H])=C1[H])C([H])([H])N(C(=O)N([H])C1([H])C([H])([H])C(F)(F)C1([H])[H])C2([H])[H]
CC1=CC=CC=C1NC(=O)NC1CCN(CC2=CC=C(C=C2)C2=NN=C3N2C2=CC=CN=C2NC2=C3C=CC=C2)CC1
[H]C1=C([H])C(=C(C([H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC(=O)[C@](N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(OC3=C(C([H])=C(F)C([H])=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@]([H])(C1=NN=C2N1C([H])=C(N=C2C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])=C([H])[H])=C(C([H])=C1Cl)C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(C([H])=C1[H])[S@](=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N1[C@@]([H])(C2=C(C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])[C@@]1([H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C(=O)O[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C(C(SC3=C([H])C([H])=NC([H])=C3[H])=C1C([H])([H])[H])C(=O)N([H])C(=N2)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C(N([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1N=C([H])C2=C(C([H])=C([H])C([H])=C12)C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=NC([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C(=O)N3C([H])([H])C([H])([H])C([H])([H])[C@]3([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])\N=C(\S[H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(OC2=C(N([H])S(=O)(=O)C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C(C([H])=C2[H])C(=O)N([H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]N(C(=O)C1=C([H])N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC1=NN=C2N1C1=C([H])C(F)=C([H])C([H])=C1N=C2N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C(N=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OP(=O)(O[H])C(F)(F)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])[C@]([H])(C1=NC(SC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(N1C([H])([H])[H])C(=O)N([H])[H])C([H])([H])[H]
[H]OC1=NSC(N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])S2)=C1C#N
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(C([H])=C(C([H])=C1[H])C(\C#N)=C(\[H])C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C2=NC([H])([H])[C@@]([H])(N2C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N1C2=C(SC3=C2C([H])=C(C#N)C([H])=C3[H])C(=O)N(C1=O)C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(Cl)=C(SC([H])([H])C([H])([H])C([H])([H])OC2=C(C(O[H])=C(C([H])=C2[H])C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C3N(C([H])([H])C2([H])[H])[C@]2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])[C@]2([H])C3=C1[H]
[H]OC1=C([H])C([H])=C2C(OC3=C(C([H])=C([H])C([H])=C3[H])[C@]2([H])C(C(=O)N([H])C2=NN=C([H])S2)(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]OC1=NC2=C(C([H])=C3C(N([H])[C@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])=C2[H])C(=C1[H])C(F)(F)F
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1Cl
[H]N1C(=NC2=C1C([H])=C([H])C(=C2[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@@]3([H])[C@@]4([H])C([H])([H])C([H])([H])C(=O)[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]23[H])C1([H])[H]
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[H]OC1=C([H])C2=NC([H])=NC(N([H])C3=C([H])C([H])=C([H])C(Br)=C3[H])=C2C([H])=C1[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])SC1=NN=C(N1N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])[H]
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[H]OC1=C([H])C(O[H])=C2C([H])=C(SC2=C1[H])C1=C([H])C([H])=C(O[H])C(F)=C1[H]
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[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C4=C(N=NN4C([H])([H])C([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C(N([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C(=O)OC([H])([H])C([H])([H])[H])[C@@]1([H])C#CC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(\N=C(/[H])C1=C(C([H])=C([H])S1)C([H])([H])[H])C(=O)C([H])([H])N1N=C(C(=C1C([H])([H])[H])[N+]([O-])=O)C([H])([H])[H]
[H]C1=C([H])C2=NC([H])=C(N=C2C([H])=C1[H])N1C([H])([H])C([H])([H])C2(C(=O)N(C([H])([H])C3=C([H])C(=C([H])C([H])=C3[H])C3=NOC(=N3)C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C2=C([H])C([H])=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C([H])=C(SC2=C1[H])C1=C([H])C([H])=C(O[H])C(F)=C1[H]
[H]N(\C([H])=C1\S\C(N(C1=O)C([H])([H])C([H])([H])[H])=C(\C#N)C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]N1C(=NC2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)C([H])([H])C([H])([H])[H])C1=C([H])N=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C1=NC(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(=C(N1[H])C1=C([H])C2=NC([H])=C([H])N=C2C([H])=C1[H])C1=NC(=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1N([H])C1=C([H])C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=NC([H])=C1C(F)(F)F
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C2=NC(=NC([H])=C2[N+]([O-])=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C([H])=C(\N=N\N(C([H])([H])[H])C([H])([H])[H])C([H])=C12)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C2C([H])=C(OC2=C1[H])C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C1=C([H])C([H])=C([H])C(O[H])=C1C(=O)C1=C(O[H])C([H])=C(C([H])=C1O[H])C(=O)O[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(O[H])C([H])=C1[H]
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[H]N(C(=O)N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=O)N(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C3[H])C(=NC2=C1[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])[H])C1=C(C(=O)OC([H])([H])C([H])([H])[H])C(=C(S1)C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C(SC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C(=O)N([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N2N=C(C3=C(C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C([H])([H])[H])C(=C([H])C2=C1C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(N([H])C2=NC3=C(C#N)C([H])=NN3C(=N2)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]C1=NN(C(=O)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=NN=NN1C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1[H])N1C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2C(=C([H])C(F)=C1[H])C1(OC2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N2C(=O)C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C2ON=C(C2=C1[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])N(\C(S1)=N\C(=O)C([H])([H])Cl)C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])N(C([H])([H])C(=O)N([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H]
CCOC1=CC=C(C=C1)N1C(=O)C2=CC=CN=C2N=C1[C@@H](C)N(CC1=C[N](O)=CC=C1)C(=O)CC1=CC=C(OC(F)(F)F)C=C1
[H]N1C(=C([H])C2=NC(=NC(=C12)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
CC1=CC(=CC=C1C(=O)N1CCOC2=CC=C(C=C2C1)C1=CC=C2N=CNC2=C1)S(C)(=O)=O
CN1CCc2c(Cl)c(O)c(O)cc2[C@H](C1)c1cccc(C)c1
[H]N1C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N4C([H])([H])C([H])([H])N(C5=C(Cl)C(Cl)=C([H])C([H])=C5[H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C([H])=C12
[H]C([H])=C([H])C([H])([H])[N+](C1=C([H])C([H])=C([H])C(OC(=O)C([H])([H])[H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(=O)N1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)C(OC2([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(SC2=NN3C([H])=C([H])C([H])=C3C(=N2)N([H])C2=NN([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C(=O)N([H])C([H])([H])C2=C(C([H])=C(N([H])C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C(=N[H])N([H])[H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C2=C(C([H])=C1[H])C([H])=C(OC([H])([H])C1=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C1[H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NN([H])N=N1
[H]N(C(=O)N([H])C([H])([H])C([H])([H])OC1=C(OC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C(=NC(=N1)C([H])([H])[H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])S(=O)(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)\N=C1\SC(=NN1C([H])([H])[H])S(=O)(=O)N([H])[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2C2=C1C1=C(C3=C([H])N(N=C3C([H])([H])C1([H])[H])C([H])([H])[H])C1=C2C([H])([H])N([H])C1=O)C(=N\OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])\C([H])([H])[H]
[H]C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C2=C1[C@@]1(OC2=O)C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C(F)C([H])=C([H])C(F)=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N2C3=C(C([H])=C([H])C([H])=C3C1([H])[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N(C(=O)C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=O)C(=O)C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]N(N1C(=S)S\C(=C(\[H])/C(=C(\[H])C2=C([H])C([H])=C([H])C([H])=C2[H])/C([H])([H])[H])C1=O)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])O[H]
[H]N=C1N([H])[C@](C(=O)N1C([H])([H])[H])(C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C(O[H])=C2C(=O)C([H])=C(OC2=C1OC([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])N(C([H])=N1)C1=NC(=C([H])C([H])=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=NC(=NN1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]\C(=C(\[H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=NOC3=C2C([H])=C([H])C2=C([H])C(O[H])=C([H])C([H])=C32)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]SC1=NC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C(F)=C([H])C([H])=C2[C@@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N1C(=O)N([H])[C@@]([H])(C(C(=O)OC([H])([H])C([H])([H])[H])=C1C([H])([H])OC(=O)C1=C([H])C([H])=C(S1)[N+]([O-])=O)C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C1=NS(=O)(=O)C2=C([H])C(F)=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(C2=NN=C(N2C([H])([H])[H])[C@@]23C([H])([H])C([H])([H])[C@@](C([H])([H])C([H])([H])SC([H])([H])C([H])([H])[H])(C([H])([H])C2([H])[H])C([H])([H])C3([H])[H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C(ON=C1C([H])([H])[H])[C@]1([H])[C@@]2([H])S[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)N([H])C1(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])P(=O)(O[H])O[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])S(=O)(=O)[C@]1([H])C([H])([H])N(C2=NC(C#N)=C([H])N=C2[H])[C@]([H])(C(=O)OC([H])([H])[H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C1=C(C([H])=C([H])N(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1=O)C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C(=O)C1=NC([H])=C([H])S1)N([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C(=C1C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C1=C(C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N(C(=O)C1(N([H])C(=O)C(F)(F)F)C([H])([H])C1([H])[H])[C@@]([H])(C1=NC([H])=C(C([H])=C1F)C1=C([H])C(Cl)=C([H])C(Cl)=C1OC([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1C([H])=NN2C([H])([H])[C@]([H])(Br)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]1([H])C(=O)N2[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])[H]
CN1CC[C@@H]([C@H](CCC[N+]23CCS[Re]22(=O)SCCN2C(=O)C3)C1)C1=CC=C(Cl)C=C1
[H]N(C1=NC([H])=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C2=C1C([H])=NN2[H]
[H]N(C1=N\C(=C(\[H])C2=C([H])N([H])C3=NC([H])=C([H])C([H])=C23)C(=O)N1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@]([H])(O[H])[C@]2(C([H])([H])O[P@](=O)(O[H])O[P@](=O)(O[H])OP(=O)(O[H])O[H])C([H])([H])[C@]2([H])[C@]1([H])N1C([H])=NC2=C1N=C(SC([H])([H])[H])N=C2N([H])[H]
[H]C1=NC(OC([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C3N(C(=O)C(=O)C3=C2[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])C([H])=N1
[H]N(C(=O)N([H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C2=C3N=C(N(C3=NC([H])=N2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=S)C([H])=C(OC2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])N=C([H])N=C3[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])C([H])([H])[C@]2(C([H])([H])OC([H])([H])[H])C1([H])[H]
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[H]C1=C([H])C([H])=C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H]
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[H]N(\C([H])=C1/SC2=C([H])C([H])=C([H])C([H])=C2C1=O)C1=C([H])C([H])=C([H])C2=C1N=C([H])C([H])=C2[H]
[H]N(C1=NN=C(O1)C1=C([H])N=C([H])C([H])=C1C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(C1=NC([H])=NN2C([H])=C([H])C(=C12)C([H])([H])OC([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])N([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])[C@@]1([H])C2=NC([H])=C([H])N2C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C(F)=C2F)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN2C(=N1)C1=C(N=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1Cl
[H]OC1=C([H])C(O[H])=C2C(OC([H])([H])[C@@]([H])(C2=O)C2=C([H])C([H])=C(OC([H])([H])[H])C(=C2[H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]OC([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])N1[H])C1=C(C([H])=NC(=N1)N([H])C1=C([H])C([H])=C([H])C2=C1OC([H])([H])O2)C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]O[C@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])[C@]4([H])[C@]5(C([H])([H])[C@@]35C(=O)C([H])([H])[C@]2(C([H])([H])[H])[C@@]1([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])N=C(SC([H])([H])[C@@]41C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C2C(=O)N(C([H])([H])OC(=O)C3=C(Cl)C([H])=C([H])C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])=C3Cl)S(=O)(=O)C2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C(=C1[H])C([H])([H])N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N1C(=NC2=C(N=NC2=C1N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])[H]
[H]N(C1=C(C#CC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=NC(=N1)C#N)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N1C(=O)C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(=N[H])N([H])[H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]