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[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]C1=C(N(C2=C1C([H])=NC(=N2)C#N)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
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[H]N(C1=C(C#CC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])[H])C(=NC([H])=N1)C([H])([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)O[H])C1=C([H])C(C2=C([H])C3=C(N2[H])C([H])=C([H])C(=C3[H])C(=N[H])N([H])[H])=C(O[H])C(=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]N([H])C(=O)C([H])([H])C1=C(N(N=C1C(=O)N([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=N\OC([H])([H])[H])\C1=C([H])C2=C(C([H])=C1[H])N(C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]([H])(N2C([H])=NC(N([H])C(=O)C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])=C2[H])C1([H])[H]
[H]OC([H])([H])C1=C(N=C(C(=C1C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])C(=O)N([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C1=C(OC2=C([H])C([H])=C(F)C([H])=C2C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
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[H]OC(=O)C1=C([H])C2=C(Cl)C([H])=C([H])C(Cl)=C2O[C@]1([H])C(F)(F)F
[H]C1=NC(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])[C@]4(C([H])([H])C([H])([H])N(C(=O)[C@@]4([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C4([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NN2C([H])=C([H])C(=C12)C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C1=NN=C(N1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]O[C@@]([H])(C([H])([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])N(C1([H])[H])S(=O)(=O)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C2C3=NN(C4=C([H])C([H])=C(C#N)C(Cl)=C4[H])[C@@]([H])([C@@]4([H])OC([H])([H])C([H])([H])C4([H])[H])[C@@]3([H])C([H])([H])C([H])([H])C2=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])O[H])C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)N([H])[H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2C(N([H])N=C2S(=O)(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)=C1[H]
[H]OC(=O)C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])OC([H])([H])[C@@]([H])(C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C(=O)O[H])[C@]([H])(O2)C2=C(O[H])C([H])=C([H])C([H])=C2[H])=C(OC([H])([H])C([H])([H])N2C([H])=NC([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C(S1)C([H])([H])C([H])([H])N([H])C1=C2SC([H])=C([H])C2=NC([H])=N1
[H]C1=C([H])C([H])=C(C(=N1)N1C([H])([H])C([H])([H])N(C(=O)OC2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C(F)(F)F
[H]C#CC([H])([H])C(=O)OC([H])([H])[C@]1([H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])[H])C(=O)[C@@]2([H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)O[C@]([H])(C3=C([H])OC([H])=C3[H])C([H])([H])[C@]21C([H])([H])[H]
CC(C)C(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC1=CC=CC=C1)C(C1=CC=CC=C1)C1=CC=CC=C1)B1O[C@@H]2CC3CC(C3(C)C)[C@]2(C)O1
[H]OC1=C([H])C(O[H])=C(Cl)C([H])=C1C1=NOC2=C1C([H])=C(C([H])=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(\C([H])=C2\C3=NC4=C([H])C(Cl)=C([H])C([H])=C4C(=O)N3C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C(=O)C([H])([H])C2=C([H])C(=C([H])C([H])=C12)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC(=NC(=C1[H])N1N=C([H])C([H])=C1[H])N1N=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C(F)=C([H])C([H])=C1C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]2([H])N3C4=C(C([H])=C([H])C([H])=C4[C@]2([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C#N)C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N(C1=C(C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]ON([H])C(=O)[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(Br)=C([H])C2=C1OC1=C([H])C(Br)=C([H])C(Br)=C1O2
[H]N(C(=O)N([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C(N(C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]N([H])C1=NC([H])=C(N=C1C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=NN2[H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])N1C(=NC(=C1C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N=C1OC2=C(C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])=C1C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3OC2=N[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C(O[H])=C([H])C(OC([H])([H])[H])=C2O1
[H]ON([H])C(=O)C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=NC([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])N2N=C([H])C(C#N)=C(N([H])C3=C([H])C([H])=C(OC4=C([H])C([H])=C([H])C(OC([H])([H])[H])=C4[H])C([H])=C3[H])C2=C1C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])[C@]1([H])[C@@]([H])(C(=O)O[H])[C@]1([H])C([H])([H])C1([H])C2=C(OC3=C1C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]1([H])C(=C([H])C([H])([H])C1([H])[H])C(=O)N(C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]O\N=C(\C(\[H])=C(\[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])/C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2N=C([H])C(=N2)C2=C([H])C(F)=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C#CC([H])([H])N([H])[C@]1([H])C([H])([H])C2=C(C([H])=C([H])C(OC(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=N[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=C(\F)C(=O)N([H])C1=C(Cl)C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H])\C([H])([H])[H]
[H]N1C(=O)C([H])([H])OC2=C1C([H])=C(C([H])=C2[H])C1=C([H])C(=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(F)(F)C(F)(F)F
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C(=O)C1([H])[H])C1=C([H])C(SC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C(=O)S\C(=C(\[H])C2=C([H])N=C([H])C([H])=C2[H])C1=O
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(=NC3=C1C([H])=C([H])C(F)=C3[H])C1=C([H])C([H])=C([H])C([H])=C1C2([H])[H]
[H]C1=C(C#N)N(C(=C1[H])C1=C([H])C(F)=C2N(C(=O)C(C2=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C#C[H])[C@@]([H])(N([H])C(=O)C1=C([H])C2=C3C(=C1[H])N(C([H])=C3C([H])([H])C([H])([H])S(=O)(=O)N2C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C2C([H])=C(N([H])C2=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([3H])([3H])C([3H])([3H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(Cl)C(=C1[H])C1=NC(SC([H])([H])C(=O)N([H])C([H])([H])C([H])([H])F)=NC2=C1C(C#N)=C([H])N2[H]
[H]N(C(=O)C1=C([H])C(=NC2=C1C([H])=C(C([H])=C2[H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(OC([H])(F)F)C([H])=C1[H]
[H]N([C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C3=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C(Br)=C1[H]
[H]O[C@]([H])([C@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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O=C1NCC2=CC=C(OCCCCN3CCN(CC3)C3=CC=CC4=C3CCC4)C=C12
[H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)C(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])OC1([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N1C2=C([H])C3=C(C([H])=C2[C@@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C(=C([H])C(=O)O3)C(F)(F)F
[H]N1C([H])([H])[C@@]2([H])C([H])([H])[C@@]([H])(N(C(=O)C3=C([H])N(C([H])=N3)C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C([H])C(OC(F)(F)F)=C3[H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N1C2=C(C3=C1C(=NC([H])=N3)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2[H]
[H]N(C1=C(C#CC([H])([H])N2C([H])=NC(Cl)=C2Cl)C([H])=NC(=N1)C#N)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1OC1=NC(OC2=C([H])C(=C([H])C([H])=C2[H])C(=N[H])N([H])[H])=C(F)C(N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1F)C(=O)N([H])[C@]([H])(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C([H])C(=C([H])N=C2C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C(\C([H])=N\N([H])C(=O)[C@]2([H])OC3=C(OC2([H])[H])C([H])=C([H])C([H])=C3[H])C(O[H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]1([H])OC(=O)C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1N([H])C(=O)C(\F)=C(/C1=C([H])C([H])=C2C([H])=C([H])N=C(N([H])[H])C2=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H]
[H]N1C2=NN(N=C2C(=NC2=C1C([H])=C([H])C(F)=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C3OC([H])([H])C([H])([H])C([H])([H])C3=C(N=C2C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C1C([H])=C([H])C(Cl)=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])N(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2F)C1=O
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C2=NC([H])=C(O2)C2=C([H])C([H])=C([H])C([H])=N2)=C([H])C([H])=C1[H]
[H]N1C([H])=C(C(=O)[C@@]2([H])N([H])[C@]([H])(SC2([H])[H])C2=C([H])C([H])=C([H])N=C2[H])C2=C1C([H])=C([H])C([H])=C2OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(O[H])C([H])([H])[C@@]([H])(O[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=C([H])C(=N1)N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])[H])C1([H])[H]
[H]\C(=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])O1
[H]N=C(N([H])[H])C([H])([H])C1=C(N(N=C1C(=O)N([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C2O[C@@]3([H])[C@]45C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C4([H])[H])[C@]51C([H])=C([H])[C@@]3(OC([H])([H])[H])[C@@]([H])(C1([H])[H])[C@]([H])(OC([H])([H])[H])C([H])([H])[H]
[H]C1=C2C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=NC1=C2C([H])=C([H])C([H])=C1[H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
Cc1cnc(NC2CCCC2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(Cl)c1
[H]N(\N=C(/C([H])([H])C(=O)C1=C([H])C([H])=C([H])S1)C(F)(F)F)C(=O)C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])C([H])(N1C2([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[C@@](C1=C([H])C([H])=C([H])C(F)=N1)(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])SC([H])=C1C(=O)OC([H])([H])[H]
[H]OC(=O)[C@@]([H])(C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=NN1[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])SC([H])=C2[H])C([H])=C1O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C(=O)O[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@]2(OC([H])([H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1SC1=C([H])C([H])=C([H])C([H])=C1C#N)C([H])([H])[H])C(=O)C(=O)N([H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]N1N=C([H])C2=C1C1=C(SC3=C1N=C([H])N(C3=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])N=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])N(C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N2C(=NC(=C(C(=O)OC([H])([H])[H])[C@]2([H])C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C(Cl)=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])N2C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)O[H])C([H])([H])[H])C([H])([H])[H]
[H]N(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C(=O)C1=C(OC([H])=C1[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])[C@@](C2=C([H])C([H])=C3N(C([H])=C([H])C3=C2[H])C([H])([H])[H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
CN1N=C(CC(=O)NC2=CC(Cl)=CC(Cl)=C2)C2=CC=CC=C2C1=O
[H]N(C(=S)N([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C2C([H])=C([H])C([H])=NN2N=C1[H])C1=C([H])C(=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C(=O)OC([H])([H])C([H])([H])OC1=C(OC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C(=NC(=N1)C([H])(C([H])([H])[H])C([H])([H])[H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C([H])C(=C([H])C(=C1[H])C1=NC2=NC(=C([H])C([H])=C2C([H])=N1)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])OC2=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC3=C(C([H])=C(OC4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])S1)C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC2=C3C([H])=C([H])N(C3=NC([H])=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=NC([H])=C2C([H])=C([H])C([H])=C([H])C2=C1C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])N1C2=C(C([H])=C1C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C3=C(S1)C([H])=C(Cl)C([H])=C3[H])C([H])=NC([H])=C2[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C(F)(F)F)[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])[H]
[H]OC(=O)[C@@]([H])(\N=C1/C(O[H])=C(O[H])\C/1=N/C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=NC([H])=C2Cl)C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(OC([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])=O)N([H])[H]
[H]C1=C(C(C(=O)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C(C([H])=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C(=C([H])C([H])=N1)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C(=O)OC([H])([H])[H]
[H]N(C(=O)C1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C(=O)C1=NC([H])=C([H])S1
[H]ON([H])C(=O)C([H])([H])S(=O)(=O)N1C([H])([H])C([H])=C(C2=C([H])C([H])=C(C3=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C3[H])C(=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])Cl)[C@@]12C(=C([H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@]1([H])[C@@]3([H])C([H])([H])C([H])([H])C(=O)[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]21[H]
COC(=O)C1=CC=C(NC(=O)C2CCN(CC2)S(=O)(=O)C2=CC=C(C)C=C2C)C=C1
[H]OC(=O)C1=C(Cl)C([H])=C(F)C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(C#N)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C(Cl)C([H])=C([H])C(Cl)=C1[H]
[H]N1[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])SSC(C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])O[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])[C@]([H])(O[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(OC([H])([H])C2=NC3=C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C([H])C([H])=C3N2C([H])([H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C3=C([H])C([H])=C(I)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
COC1=CC=C(\C=N\NC2=NC3=C(N=CN3[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C(N)=N2)C=C1Cl
[H]N(C1=NC([H])=C([H])C(=N1)N1C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CN(C)CC[C@H](CSC1=CC=CC=C1)NC1=C(C=C(C=C1)S(=O)(=O)NC1=NN(C)C2=C1C=NC(=N2)N1CCN(CC2=C(C=CC=C2)C2=CC=C(Cl)C=C2)CC1)[N+]([O-])=O
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C(Cl)=C(OC([H])([H])C4=C([H])C(F)=C([H])C(F)=C4[H])C([H])=C3[H])C2=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C(=C([H])C([H])=C1I)C(=O)C#CC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C(OC([H])([H])C2=C(ON=C2C([H])([H])C([H])([H])[H])C([H])([H])[H])=NC2=C(C1=O)C(=C([H])C(=O)O2)C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C(O[H])C([H])=C2C([H])([H])[H])[C@]2([H])[S@@](=O)[C@@]1([H])C([H])([H])[C@]2([H])S(=O)(=O)OC1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H]
[H]N(C(=O)[C@]([H])(C([H])([H])C(=O)N1C(=O)[C@]([H])(C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C([H])([H])C(=O)C1([H])[H])C([H])([H])C([H])([H])[H])C1=NN=NN1[H]
COC1=CC=C(NC2=C(C(C)=NN2C2=C(Cl)C=CC=C2)C2=CC3=NC=CN=C3C=C2)C(=C1)C(O)=O
[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1Cl)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N1C(=O)N(C2=C([H])N=C([H])C([H])=C2C1=O)C([H])([H])C1=NSC2=C1C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C(=NC2=C(C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C(N(C([H])=N2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H]
[H]C1=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])(C4=C([H])C([H])=C([H])C(Cl)=C4Cl)C([H])([H])C3([H])[H])=C([H])C([H])=C2S1
[H]N1C([H])=C(C2=C([H])C(F)=C([H])C([H])=C12)C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C(F)C([H])=C3[H])C2=O)C([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)N(C(=O)C1=C([H])C2=C(OC([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C([H])=C1OC([H])([H])[H])[C@]1([H])C([H])([H])C2([H])N(C([H])([H])C3=C([H])C([H])=C([H])O3)[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]ON(C(=O)C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])C1=NN=C(N1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C2OC([H])([H])C([H])([H])OC2=C1[H]
[H]C1=C(N2N=C(OC([H])([H])[H])C(N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])[C@]3([H])C([H])([H])OC([H])([H])C3([H])[H])=C2S1)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])[C@]([H])(OC([H])([H])[H])C([H])([H])[H]
[H]N=C(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(Cl)C([H])=C2[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C2N=C([H])C([H])=C([H])C2=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)[C@]23C([H])([H])[C@]4([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@](C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])(C4([H])[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C1=C(N2C([H])([H])C([H])([H])N(C(=O)[C@]3([H])N([H])C([H])([H])C([H])([H])[C@]3([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C(F)=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C1N=C([H])N2[C@]1([H])C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]([H])(OC([H])([H])[H])[C@@]1([H])OC([H])([H])[H])C#CC1=NC([H])=C([H])S1
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])N(C2=O)C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C2([H])N(C([H])([H])C3=C([H])C([H])=C4C([H])=C(F)C([H])=C([H])C4=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(=C(N([H])[C@@]([H])(C([H])([H])SC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])[N+]([O-])=O
[H]OC(=O)C([H])([H])[C@@]1(C(=O)N([C@@]([H])(C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]1([H])N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])N(C2=C(C([H])=C(F)C(=N2)N2C([H])([H])[C@]([H])(N([H])[H])[C@]([H])(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C2([H])[H])C1=O)C1([H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(SC([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C2=NC([H])=C([H])N2C([H])([H])[H])=NC(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=NN=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])[C@@]([H])(N([H])C([H])([H])[C@@]2([H])C([H])([H])[C@]2([H])OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])S(=O)(=O)C([H])([H])[C@@]1([H])C([H])([H])C1=C([H])C(OC([H])(C(F)(F)F)C(F)(F)F)=C(N([H])[H])C(F)=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])O[H])=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])[C@]1([H])C2=C(C([H])=C([H])C(Cl)=C2[H])[C@]([H])(C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=N[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CC(SC1=NN2C(C=C1)=NN=C2C1=CC=CC(Cl)=C1)C1=CC=NN1
[H]OC1=C([H])C([H])=C([H])C2=C1N=C(N=C2N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N([H])C1=C(C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=NO[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C2=NC([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC1=C2C(=C(S1)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2=O
[H]OC(=O)C1=C(C([H])=C(OC2=C([H])C([H])=C(C([H])=C2N([H])C(=O)C2=C([H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C(F)(F)F)C([H])=C1[H])C(=O)O[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=NC2=NC3=C([H])C([H])=C([H])C([H])=C3N=C12
[H]O[C@]1(C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])C1=C([H])N(C2=C1C(F)=C([H])C([H])=C2[H])C([H])([H])C(=O)N([H])OC([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C(S1)C([H])([H])N(C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C(F)(F)F)C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]C1=NC([H])=C(N(C(=O)C([H])([H])F)C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])[H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=N1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C1=NC2=C([H])C([H])=C(F)C([H])=C2C(C([O-])=O)=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C(=N1)C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(O[H])C([H])([H])[C@]([H])(O[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])C#CC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])C1=NC(=C([H])C([H])=N1)C1=C([H])C2=C(N1C([H])([H])C([H])([H])F)C([H])([H])C([H])([H])N([H])C2=O
COC1=CC(C)=C(C(C)=C1)S(=O)(=O)N(C)CCOCC(=O)N1CCN(CC1)C1CC2CCC(C1)N2C
[H]OC([H])([H])[C@]1([H])O[C@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@@]([H])(O[H])[C@@]1([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)OC([H])(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=NN1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C([H])C2=C(C(=NC2([H])[H])C2=C([H])C(F)=C(C([H])=C2[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=N1
[H]N([H])C1=NC([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C(=C1[H])C1=NN=NN1C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C(=NC2=C(Br)C([H])=NN12)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
FC1=CC=C2C=CC=C(N3CCN(CCCCOC4=CC=C5CNCC5=C4)CC3)C2=C1
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C3=C2OC([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C3=C([H])C([H])=C(O[H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])[C@](C(=O)N([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C([H])N(C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=NC([H])=C2C([H])=C(N(C2=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(N(N=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC1=C([H])C(=NC(SC([H])([H])C(=O)C2=C([H])C(O[H])=C(O[H])C([H])=C2[H])=N1)C([H])([H])[H]
[H]N(C(=O)C1=C([H])N([H])C(=O)C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1(OC(=O)C(=C1C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C([H])C2=NSN=C2C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C(=NN1C([H])([H])[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)N2C([H])=NN=C2[H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])[N+](C1=C([H])C([H])=C([H])C(OC(=O)C([H])([H])[H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(N([H])C3=NC([H])([H])C([H])([H])C([H])([H])N3[H])=C([H])C([H])=C2[H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C(O2)C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=NC(=NC(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C1\C([H])([H])[C@]2([H])[C@]([H])(O[H])C([H])([H])[C@@]([H])(C(\[H])=C(/[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]2([H])C1([H])[H]
[H]N(C1=NN(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC3=C(F)C([H])=C(F)C([H])=C3[H])C([H])=C12
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N(C(=C(N2C(=O)C3=C([H])C([H])=C4C5=C(C([H])=C([H])C(C2=O)=C35)C([H])([H])C4([H])[H])C1=O)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(N([H])S(=O)(=O)C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)=C2[H])N(C2=C([H])C3=C(C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C(=C([H])C([H])=C2[H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N(C2=C3C(=C([H])C([H])=C2[H])N(C([H])=C3C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OP(=O)(O[H])C([H])(N([H])C1=NC([H])=C(S1)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])P(=O)(O[H])O[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])I)[C@]([H])(O[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
[H]N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])F
[H]N(C(=O)[C@]([H])(N1C([H])([H])C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])[C@@]1([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]13C([H])([H])N(C([H])([H])C4([H])C([H])([H])C4([H])[H])C([H])([H])C([H])([H])[C@@]21C([H])([H])C1=C(C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[H])C3([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N1C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C1=NOC(=N1)C1=C([H])C(Cl)=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]2(C3=C([H])C(F)=C(F)C([H])=C3[H])C([H])([H])N(C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C(OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC1=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@]22C([H])([H])C(=O)C([H])([H])C([H])([H])[C@@]12OC([H])([H])[H]
[H]C1=C2N(C(=O)OC2=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])([H])OC1=NO[C@]2(C1([H])[H])C([H])([H])[N@+]1([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=NC(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(SC(F)(F)F)C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=NN([H])C(=C2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]C1=NC2=NC(=C(N2C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C(=C(F)C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H]
CNC1=NC(=C(S1)C1=NC(NC2=CC(=C(C)C=C2)S(=O)(=O)N2CCOCC2)=NC=C1)C1=CC=CC=C1
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2OC1([H])[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C#N)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C2N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[C@]([H])(N(C(=O)C([H])([H])[H])C([H])([H])C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C2=NC(=C1[H])C(F)(F)F)C1([H])C([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C2/SC(=S)N(C2=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[N+]([O-])=O
[H]OC1=C(\C([H])=N\C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)C([H])([H])N2C(=O)C(N([H])S(=O)(=O)C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])[H])[C@@]([H])(N([H])C1=NC2=C(N=C([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C2=C(C([H])=C([H])C3=C2C([H])([H])C([H])([H])O3)C([H])([H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C(Cl)C([H])=C1C1=C(C([H])=NN1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(O1)C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C3=C(C([H])=C([H])O3)C(OC([H])([H])[H])=C1C(=O)C([H])([H])[H])C(C(=O)C([H])([H])[H])=C2OC([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])N1C(=NC2=C1C(=O)N(C([H])([H])[H])C([H])([H])N2C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2N(C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1N([H])[H])[N+]([O-])=O
[H]OC(=O)C1=C([H])C(N([H])C2=C([H])C([H])=C(C([H])=C2OC(F)(F)F)[N+]([O-])=O)=C([H])C([H])=C1[H]
[H]N=C1SC(C#N)=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])N1C([H])([H])C([H])=C([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C(=NC3=C2N=C([H])N=C3N2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(\C(=N/C#N)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(C(=N1)C1=C([H])C([H])=C(Br)O1)C([H])([H])C1=C2C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)C([H])([H])N2N=C([H])N=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])C(=O)N1N=C([H])C2=C1C([H])=C(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C1[H])C([H])=C2[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])N2C(=O)C(=NC(Cl)=C2C([H])([H])[H])N([H])C2([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C2([H])[H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C3=C([H])C4=C(C([H])=C3[H])C([H])([H])C([H])=N4)[C@@]1([H])C2([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(C([H])([H])C1=C([H])C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(OC(=N1)C(=O)[C@]1([H])C([H])([H])C2=C(C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])N2C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])[C@]2([H])SC1([H])[H])N([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@](N(C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(C2=NC(=C3N2C([H])=C([H])N=C3N([H])[H])C2=C(F)C([H])=C(C([H])=C2[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])(P(=O)(O[H])O[H])P(=O)(O[H])O[H]
[H]OC(=O)C(OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C12)C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])N([H])N=C1[H]
[H]C1=C([H])C2=C(C([H])=C([H])C([H])=C2C([H])=N1)S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N(C([H])([H])[H])S(=O)(=O)C1=C2C([H])=C([H])N=C([H])C2=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(C1=O)C1=C(N3C4=C1C([H])=C([H])C([H])=C4C([H])([H])C([H])([H])C3([H])[H])C1=C2C2=C(N1[H])C([H])=C(C([H])=C2[H])C([H])([H])N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C3C([H])=C(C4=C([H])C([H])=C([H])C([H])=C4[H])C(=NC3=N2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=NN=C(N3[H])C3=NC([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=[N+]2[O-])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C2O[C@@]3([H])C4=C(C([H])=C(C([H])=N4)[N+]([O-])=O)C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C(=O)N([H])C1=C(Br)C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(C2=C1OC1=C([H])C([H])=C([H])C([H])=C1C2=O)[N+]([O-])=O
[H]N([H])C1=NC(N([H])[H])=C(C2=C([H])C(\N=N\N(C([H])([H])C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C([H])([H])C([H])([H])OC(=O)C([H])([H])[H])=C(Cl)C([H])=C2[H])C(=N1)C([H])([H])C([H])([H])[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])N(C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])[H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)N1N=NC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(OC([H])([H])[H])C(=C([H])C(OC([H])([H])[H])=C1Br)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@](O[H])(C#CC([H])([H])[H])[C@@]([H])(O[H])C([H])([H])[C@@]21C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(O[H])C1=C([H])C([H])=C(C2=NN=C3C([H])=C([H])C(SC4=C([H])C([H])=C(F)C([H])=C4F)=C([H])N23)C(=C1[H])C([H])([H])[H]
[H]N(C1=NC2=C(S1)C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])N2C(=NC(=C2C2=C([H])C([H])=NC(=N2)N([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
CCOC1=NO[N](O)=C1S(=O)(=O)C1=CC=CC=C1
[H]N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C([H])C([H])=C3[H])C(=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C(N([H])C(=O)[C@]([H])(N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C(C(=O)C([H])([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C#N)C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C1=C(C([H])=C([H])S1)C1=NC2=C([H])C([H])=C([H])C([H])=C2S1)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C(=O)N1C([H])([H])[C@@]([H])(N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(C#N)C(OC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C#N
[H]N1C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C#CC([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC(=O)N(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=NC(N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C(C([H])=N3)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C2C([H])=C(SC2=N1)C([H])([H])C([H])([H])[H]
[H]N1[C@@]2([H])C3=C(N(C4=C(C([H])=C(C([H])=C34)S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N1C([H])=C([H])N=C1C1=NN(N=N1)C1=C([H])C(F)=C([H])C(C#N)=C1[H]
[H]N([H])N([H])C(=O)[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(\C([H])=C1/C(=O)N([H])C(=O)C2=C([H])C([H])=C(C([H])=C12)C1=C([H])OC([H])=C1[H])C1=C([H])C(F)=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N1C([H])=C(C2=C([H])C(F)=C([H])C([H])=C12)C1=C([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])C([H])(N([H])C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H]
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC([H])=NC2=C1N=C([H])N2[C@]1([H])O[C@]([H])(C(=O)N([H])C([H])([H])[H])[C@@]([H])(O[H])[C@@]1([H])O[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(OC1=O)C([H])=C([H])C([H])=C2[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])=C([H])[C@@]2([H])[C@]3([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]22C4=C(C([H])=C([H])C(OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC5=C([H])C([H])=C6C(=C5[H])[C@]57C([H])([H])C([H])([H])N(C([H])([H])C8([H])C([H])([H])C([H])([H])C8([H])[H])[C@]([H])(C6([H])[H])[C@@]5([H])C([H])([H])C([H])([H])C([H])([H])C7([H])[H])=C4O[C@@]12[H])C3([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C(=C1[H])C(=N[H])N([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=NC(=NC2=C1N=NN2C1=C([H])C([H])=C(C([H])=C1Br)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N1C2=C(C([H])=C(C([H])=C2[H])[N+]([O-])=O)C2=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1N([H])C(=O)C2([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=NOC(=N1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]N(C1=NC2=C(N=C(N=C2[H])N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])N1C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(O1)C1=C(N=C(SC([H])([H])[H])N=N1)C1=C([H])C([H])=C([H])O1
[H]N1C([H])=C(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C(=NC3=C2C([H])=C([H])N=C3[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C(=C12)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C([H])=C([H])N([H])C1=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3N=C(N=C(N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C3=N2)C2=C([H])C([H])=C([H])C3=C2C([H])=C([H])N3[H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2F)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])OC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NC2=C(S1)C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1=C(N([H])C(=O)C2=C([H])C3=C(N2[H])C([H])=C([H])C(Cl)=C3[H])C([H])=C([H])C(=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])N=C1[H])[C@@]([H])(C1([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])S(=O)(=O)N1C2=C([H])C(Br)=C([H])C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C2C(=O)C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C(=C1C([H])=C([H])N=C([H])C1=C2C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1(C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])Br)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC2=C(Cl)C([H])=C(C#N)C([H])=C2[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C(=O)N([H])C1=C([H])N=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=NC(=C([H])C(=C1[H])C1=C([H])N=C2N=C(OC2=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(C#N)[C@@]1([H])C(=O)N(C2=C([H])C([H])=C(F)C([H])=C12)C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[N+]([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C#CC([H])([H])OC([H])([H])[H]
[H]O[C@@]1(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C3=C(C([H])=NN3C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])[C@]12C([H])([H])[H]
[H]N(C1=NC([H])=C([H])S1)C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C([H])([H])C([H])([H])OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
CN1N=C(CC(=O)NC2=CC=C3C=CC=CC3=C2)C2=CC=CC=C2C1=O
[H]N([H])C1=NC(=C(N1[H])C([H])([H])[H])[C@]1([H])[C@@]([H])(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1N=C(C2=C1C([H])=C([H])C(=C2[H])C(=O)N1C([H])([H])C([H])([H])C2(OC3=C(N=C([H])C([H])=C3[H])C(=O)C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]SC([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C1=C([H])C2=NC([H])=C([H])C(OC3=C([H])C([H])=C(N([H])C(=S)N([H])C(=O)C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C3F)=C2S1)C([H])([H])[H]
[H]OC(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])N(C3=C([H])C([H])=C([H])N=C3[H])[C@@]2([H])C1([H])[H]
[H]O\N=C(\C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C(\N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])=C(/[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(C([H])=C([H])S1)S(=O)(=O)N([H])C1=C(Cl)C(=NO1)C([H])([H])[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1C#N
[H]N(C(=O)C1=C([H])N(C2=C(N([H])C(=O)C([H])=C2[H])C1=O)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(O[C@@]2([H])C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C2([H])[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C(=O)[C@@]1([H])N(C([H])([H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H]
[H]OC(=O)C1=C([H])C(N([H])C2=C([H])C(=O)C(=O)C3=C2C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C1[H]
CN(C)C(=O)C(CN1CCC2(CC1)OCCC1=C2SC=C1)CC1=CC=CC=C1F
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C1(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C(SC(=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)C(F)(F)F
[H]OC1=C(F)C([H])=C(C([H])=C1[H])C1=NN(C2=C1C(=NC([H])=N2)N([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C(=C2C(=O)N1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@]2([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]3([H])N(C(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])[C@]([H])(SS[C@]4([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N5C([H])([H])C([H])([H])C([H])([H])[C@@]5([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C5=C([H])C([H])=C([H])C([H])=C5[H])C([H])([H])C5=C([H])N([H])C([H])=N5)C([H])([H])SSC2([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C4([H])[H])C3([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])[C@]4([H])[C@]5(C([H])([H])[C@@]35C(=O)C([H])([H])[C@]2(C([H])([H])[H])[C@@]1([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])N=C(SC([H])([H])[C@@]41C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C2N1[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C([H])([H])C1([H])C([H])([H])C1([H])[H])C2([H])[H]
[H]OC(=O)C1=NN2C(N=C(C([H])=C2C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1Br
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])N=C(F)C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C(=NN=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N2C([H])=C(C3=C([H])C([H])=C([H])C([H])=C23)S(=O)(=O)C2=C([H])C([H])=C([H])C(F)=C2[H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H])[C@]([H])(C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]N(C(=O)C1=C([H])C(F)=C(C(=C1[H])C1=C([H])C2=C(C([H])=C1[H])C1(C(=O)N2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]OC(=O)[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])[C@]4([H])C([H])([H])[C@]3(C([H])([H])[C@]4([H])C([H])([H])OC(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]12[H]
[H]N(C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3C([H])=C(F)C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C23C([H])=C([H])C1(OC([H])([H])[H])C1([H])OC4=C5C(=C([H])C([H])=C4OC([H])([H])C(=C([H])[H])C(=O)OC([H])([H])[H])C([H])([H])C2([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C315
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)O[C@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)C(F)(F)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=[N+](C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N(C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC(=NC(=N1)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])[C@]2([H])C([H])([H])C([H])([H])[C@]([H])(OC3=C([H])C(=C([H])C([H])=C3[H])C(=O)O[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C(=O)C1=C2N(C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1(O[C@@]([H])(C([H])([H])[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC(=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N(C(=O)C1=C(C3=C(O1)C([H])=C([H])C(=C3[H])S(=O)(=O)N1C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@]([H])(S[C@@]12O[C@@]([H])(O[C@]1([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])[C@]([H])(F)C4=C([H])C(=O)C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3(F)[C@@]([H])(O[H])C([H])([H])[C@]21C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])O[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C3OC4=C(C([H])=C([H])C(=C4[H])N(C([H])([H])[H])C([H])([H])[H])C3=C2[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]OC1=C2N([H])C(=O)C([H])=C([H])C2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC(=O)N([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1C([H])=C([H])C2=C([H])C(F)=C(Cl)C([H])=C12
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C2=C1N([H])N([H])C2=O
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C([N+]#N)=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])N=C([H])N=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@]1(C3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])O3)C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C(N([H])C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(N([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2O[H])P(=O)(O[H])O[H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(O1)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C(N([H])C2=C([H])C([H])=C([H])C([H])=C12)=C(C#N)C#N
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1(N(N=C(C2=C([H])C(F)=C([H])C([H])=C2F)C1([H])[H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H]
C=CC(=O)NC1=CC=C(C=C1)S(=O)(=O)NC1CCN(CC1)C(=O)OCC1=CC=CC=C1
[H]C([H])=C(C1=C([H])C([H])=C([H])C(=C1[H])C(N([H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C(=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)[C@]([H])(N(C(=O)[C@@]1([H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(N=C1C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
COC1=C(C=CC=C1)C1=CN2C(=N1)N=C(C)C(CN)=C2C1=CC=C(Cl)C=C1
[H]C1=C(ON=C1C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])SC1=NN=C(N1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]OC1(C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(F)C([H])=C23)C([H])([H])C1([H])[H])[C@@]([H])([S@+]([O-])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])[C@]1([H])N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C2=C(C([H])=NN2[H])C([H])=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(C([H])=C(\C([H])=C(/[H])C2=C([H])N=C([H])S2)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])[C@]2([H])N(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2([H])[H])C([H])([H])C1=C([H])N=C(C([H])=N1)C([H])([H])[H]
[H]O[C@]([H])(C(F)(F)F)[C@]1(C(=O)N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[C@@]([H])(N([H])[C@@]2([H])C([H])([H])C([H])([H])OC([H])([H])[C@@]2([H])OC([H])([H])[H])C1([H])[H]
[H]N([H])C(=O)[C@]1([H])OC2=C([H])C([H])=C(F)C([H])=C2[C@@]2(N([H])C(=O)N([H])C2=O)C1([H])[H]
NC1=NC(=CC=N1)N1C=C(C2=C1C=C(Cl)N=C2)C1=C(Cl)N=CC=C1
[H]ON1C(=O)\C(=C(\[H])C2=C(C([H])=C(N2[H])C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C2=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N(C1=C([H])C([H])=C([H])C(F)=C1[H])C1=C2C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN(C([H])=N1)C1=C([H])C(=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(=C([H])C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)OC([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(O[H])C(=C(/[H])C([H])([H])C1=C(O[H])C2=C(C(=C1OC([H])([H])[H])C([H])([H])[H])C([H])([H])OC2=O)\C([H])([H])[H]
COC1=CC(NC(=O)\C=C\C2=CC(O)=C(O)C=C2)=CC=C1
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2OC([H])([H])[C@]([H])(C2=C1[H])C([H])([H])C([H])([H])N([H])[H]
[H]N1C([H])=C(C(OC2=C([H])C([H])=C(C#N)C([H])=C2[H])=C1C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])[C@@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=C1OC([H])([H])O2)C([H])([H])C(\C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])=C(\C([O-])=O)C1=C([H])C2=NSN=C2C([H])=C1[H]
[H]N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1N(C(=S)N(C2=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])S1
[H]\C(=C(\[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C1=C(C(=O)N([H])C2=C(Cl)C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(C(=C2N=C(SC2=C1C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])N([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NOC3=C([H])C(F)=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)N2C3=C(N([H])C(=O)C4=C2C([H])=C([H])C([H])=C4[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])N(N=C12)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1S(=O)(=O)N([H])[H])N1N=C(C([H])=C1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(F)(F)F
[H]C1=NC2=C(C([H])=C([H])C([H])=C2C(C2=C([H])C(=C([H])C([H])=C2[H])C2=C([H])C([H])=C(F)C(=C2[H])S(=O)(=O)C([H])([H])[H])=C1C([H])([H])[H])C(F)(F)F
[H]N1C(=O)S\C(=C(\[H])C2=C([H])C(Br)=C(OC([H])([H])[H])C(Br)=C2[H])C1=O
[H]OC(=O)C([H])([H])C1=C2N(C3=C([H])C(C#N)=C([H])C([H])=C13)C([H])([H])[C@]([H])(N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N3C([H])([H])C([H])([H])N(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(SC3=C([H])C(Br)=C([H])C([H])=C23)C(=N1)N1C([H])([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=N1)N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C(F)(F)F
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])C(=O)C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C(F)C(F)=C(F)C(F)=C1F
[H]N1C(=S)S\C(=C(\[H])C2=C([H])C3=C(N([H])C(=N3)C3=C([H])C([H])=C([H])C(=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C1=O
[H]C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C([H])=NC2=C(SC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)N=C([H])N=C12
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])N(N=N2)C([H])([H])C([H])([H])C([H])([H])N([H])C(=S)N([H])C2=C([H])C(C(=O)O[H])=C(C([H])=C2[H])C2=C3C([H])=C([H])C(=O)C([H])=C3OC3=C2C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
[H]C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N2C([H])([H])C([H])([H])C3(C([H])([H])C([H])([H])N(C(=O)C4=C([H])C([H])=C(Cl)C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=N1)C(=O)C(\[H])=C(/[H])C1=C(C#N)C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C#CC([H])([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C3C([H])=C(OC([H])([H])[H])C([H])=C([H])C3=C2[H])C(=O)N(C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N1C([H])=C([H])N=C1C([H])([H])SC1=NC2=C([H])C([H])=C([H])C([H])=C2C2=NC(=NN12)C([H])([H])[H]
[H]OC1(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])S(=O)(=O)C2=C([H])C([H])=C([H])S2)C([H])([H])C1([H])[H]
[H]C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C(N(C2=NC(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1Br
[H]N(C(=O)[C@@]1([H])N([H])C([H])([H])C2=C(C3=C([H])C([H])=C([H])C([H])=C3S2)C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C(Cl)C([H])=C(Cl)C([H])=C1S(=O)(=O)OC1=C(C([H])=C(Cl)C([H])=C1Cl)C(=O)N([H])C1=C([H])C([H])=C(SC2=NC3=C(S2)C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])=C1[H]
[H]OC1=C([H])C2=C3C(N([H])C(SC([H])([H])[H])=C3C([H])([H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])C(=C([H])[C@]23[H])C([H])([H])[H])=C1[H]
[H]OC1=C(C(=O)C([H])([H])[C@@]([H])(C([H])([H])[H])C1([H])[H])[C@@]1([H])C2=C(OC3=C1C(=O)C([H])([H])[C@]([H])(C([H])([H])[H])C3([H])[H])C([H])=C([H])C([H])=C2[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H]
[H]C1=C2C([H])([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])[C@@]([H])(Br)C(=O)[C@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3([H])[C@]2(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
ClC1=CC=CC(=C1)C(=O)N1CCC[C@@H](C1)C1=NC(=NO1)C1=CC=CC=C1
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC([H])([H])C([H])([H])N1N=NC(=N1)C1=C([H])C([H])=C(OC([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(OC([H])([H])C([H])([H])SC(=S)SC([H])([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C(N(N=C1C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1(N([H])C(=O)C(F)(F)F)C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C(Cl)=C([H])C(Cl)=C1C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC([H])=NC2=C([H])C([H])=C(Cl)C([H])=C12
[H]OC(=O)C1=C(N([H])S(=O)(=O)C2=C(\C([H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C(C2=C([H])C([H])=C([H])C([H])=C2N1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=NN=C(O1)S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])N1C2=C(OC([H])([H])C1([H])[H])C([H])=C([H])C(F)=C2[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C2C(=C1[H])C1=NO[N+]([O-])=C1C([H])([H])C2([H])[H]
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[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])N([H])C(=O)C1=C([H])OC([H])=C1[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])OC2=C(C1=O)C(O[H])=C(OC([H])([H])[H])C(O[H])=C2[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(C2=C1C([H])([H])[C@]1(C(=C2[H])C([H])([H])C([H])([H])N(C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(O[H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC1=C(C(=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N(C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]O[C@]([H])(C([H])([H])C(\[H])=C(/[H])[C@@]1([H])[C@]([H])(O[H])C([H])([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C1(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(N=C(N1C1=C2OC([H])([H])C([H])([H])OC2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C2N([H])C3=C(C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C([H])([H])N2N=C1C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]C1=C([H])C(OC(=O)C([H])([H])[H])=C(SC([H])([H])C([H])([H])C#CC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C(Cl)C(=C(Cl)C([H])=C2[H])C([H])([H])OC2=C3N=C(OC([H])([H])[H])N(C3=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(O2)C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C2=C([H])N=C([H])N=C2[H])C([H])=C1C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(SC3=C([H])C([H])=C(Cl)C([H])=C3[H])C3=C(SC([H])([H])[H])C([H])=C([H])N=C3N2C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C([H])C(Cl)=C3[H])C([H])([H])N(C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N=C1N2N=C(SC2=NC(=O)\C1=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=NC([H])=C(Cl)C(=N1)N([H])C1=C(F)C([H])=C([H])C([H])=C1C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C2N(C(=O)C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])OC2=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@@]([H])(C1=C([H])C([H])=C3C(N([H])C4=C3C([H])([H])C([H])([H])N3C([H])([H])[C@]5([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])[H])[C@@]3([H])[C@@]4(C(=O)OC([H])([H])[H])C5([H])[H])=C1[H])C([H])([H])[C@@]1([H])[C@@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(S[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C(=O)N1C([H])([H])[C@]2(C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H]
[H]N(N([H])C(=O)C([H])([H])SC1=NN=C(N1N([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C([H])([H])[H])C(=O)C([H])([H])[H]
[H][C@]12SC=C(N1C(=O)\C2=C\C1=CN2C(SC3=C2C=CC(C)=C3)=N1)C(=O)O[Na]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1N=C(C2=C([H])C([H])=C(N=C12)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC([H])=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@]1([H])N(C2=C([H])C([H])=NC(=N2)N2C([H])=NC([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])N1C2=C(SC([H])([H])C1([H])[H])C([H])=C(Cl)C([H])=C2[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=NC3=C(C(OC([H])([H])[H])=C([H])C([H])=C3[H])[C@]2([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])[N+]([O-])=O)C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C1=NC2=C(C([H])=N1)C(=C(Br)C(=O)N2C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]1([H])[C@@]([H])(N(C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C([H])([H])C1([H])O[C@@]([H])(C([H])([H])[H])[C@@]([H])(O1)C([H])([H])[H]
[H]N(C(=O)C1=C(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])=C2\C1=[N+](/[O-])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=C([H])C([H])=C1[H]
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[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=O)C21C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H][C@@]12C[C@]1([H])N([C@@H](C2)C#N)C(=O)[C@@H](N)C1CCN(CC1)C(=O)C1=CN=C(C=C1)C(F)(F)F
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[H]N([C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]N(C(=O)C([H])([H])C([H])([H])SC1=NC(=C([H])C(=N1)C(F)(F)F)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])=C([H])N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
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[H]N(C1=NC(=NC2=C([H])C([H])=C([H])C([H])=C12)C(F)(F)F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])N([H])C(=O)C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC(=O)C(\[H])=C(\C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2C1=C([H])C(=C([H])C(=C1OC([H])([H])C(F)(F)F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])N(C([H])=N1)C1=C(C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2O1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C([H])=C(C2=C([H])C([H])=C(F)C(F)=C12)C([H])([H])N1C2=C([H])C([H])=C([H])N=C2N=C1C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C#CC([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])N(C2=C([H])C(=C(Cl)C([H])=C2[H])C(F)(F)F)S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C([H])=N1)C1=C([H])C2=C(C([H])=C1[H])N(C1=C2C2=C(C(=O)N([H])C2([H])[H])C2=C1C([H])([H])C([H])([H])C1=C2C([H])=NN1C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=NC(=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])([H])C([H])([H])C1=C2SC(=N1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N(C1=C([H])C([H])=C2N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(N(C3=NN(N=N3)C([H])([H])[H])C([H])([H])C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C2=N1)C([H])([H])C([H])([H])[H]
[H]C1=C(N(C2=C1C([H])=NC(=N2)C#N)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C([H])=C(Cl)C(=C2[H])C([H])([H])C2=NN=C(S2)C2=C(C([H])=C([H])O2)C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]OC1(C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C(N=C1[H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=C([H])C2=C([H])C(Cl)=C([H])C([H])=C12)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1([H])N(C2=NN=C(S2)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])[C@]([H])(F)C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(I)=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN([H])C2=NC(C3=C([H])C([H])=C([H])S3)=C(Br)C([H])=C12
[H]N1C([H])([H])[C@]2([H])C([H])([H])[C@]2(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C1([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C(N([H])S(=O)(=O)C(F)(F)F)C([H])=C([H])N=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]N(OC([H])([H])[H])C(=O)C1=C([H])C([H])=C(C(N([H])C2=NC(=NC(=N2)N2C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C2([H])[H])N(C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]C1=NN=C(N1C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1C([H])([H])[H])C1=C(Cl)C(Cl)=C([H])C([H])=C1[H]
[H]C1=C(C(=O)C(=O)N2C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C([H])C([H])=C2N1C1=C([H])C([H])=NC([H])=C1[H])C1=C(C([H])=C([H])N=C1[H])C([H])([H])[H]
[H]C1=C([H])[N+](=C([H])C([H])=C1N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[N+]1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(Br)C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N1N([H])[C@@]2(OC3=C([H])C([H])=C([H])C([H])=C13)C(=O)N(C1=C([H])C([H])=C([H])C([H])=C21)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C1OC(C1=C([H])C([H])=C([H])C([H])=C1[H])=C(C2=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=C3C(=C([H])C(=C2[H])C([H])([H])[H])N(N=C3C([H])([H])C([H])([H])C2=C([H])C([H])=C3OC([H])([H])C([H])([H])C3=C2[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])S(=O)(=O)C1=C([H])C(I)=C(N([H])S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C([H])=C1[H]
[H]N(C1=NC([H])=C2C(=N1)N(C(=O)C([H])=C2C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]OC1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]([H])(O[H])C([H])([H])N2N=C(C3=C2C([H])([H])C([H])([H])N(C3([H])[H])S(=O)(=O)C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])N=C2C([H])=C([H])N(C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=NON=C12
[H]N(C1=NC([H])=NC2=C([H])C([H])=C(C#CC([H])([H])N([H])C(=O)C([H])([H])OC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C(=C2[H])C(=O)N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N2N1N=C(C2=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C1([H])C([H])([H])C1([H])[H]
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[H]C1=NC(=C([H])N=C1N1C(=O)C(Br)=C(OC([H])([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C([H])([H])[H])[C@@]([H])(N2C1=NC1=C2C(=O)N(C(=O)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
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NC(=S)N1N=C(CC1C1=CC2=CC=CC=C2C=C1)C1=CC=C(Cl)C=C1
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[H]N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C([H])C(=C1[H])N1N=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])S(=O)(=O)C([H])([H])[H])[C@@]1([H])C2=NN(C(=C2OC([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)[C@@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(O[C@@]([H])(C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)OC1=C2C(=C([H])[N+](=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])OC(OC2([H])[H])(C([H])([H])[H])C([H])([H])[H])[N+]([O-])=O
CC[C@@H](CO)N1[C@@H]([C@@H](O[C@@H](CC(O)=O)C1=O)C1=CC=CC(Cl)=C1)C1=CC=C(Cl)C=C1
[H]OC1(C2=C([H])C([H])=C(Cl)C(=C2[H])C(F)(F)F)C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])OC(=O)N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1(C([H])([H])O[C@]2(N(C(=O)C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(OC([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C2OC([H])([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C(=NC(OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1C#N)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C(F)=C(C(F)=C1[H])C([H])([H])N1C(=O)N(C(=O)C2=C1C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C(O[H])(C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1(OC([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])N=C1[H]
[H]N(C1=NC(=C(S1)C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])N2C([H])=C([H])C([H])=C2C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C(F)=C([H])C(=C1[H])C([H])([H])N(C(=O)O[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
COC1=CC=C(C=C1C1=C2C=CC(OC3=CC=C(F)C=C3F)=NN2C=CC1=O)C1=NN=C(C)O1
[H]O[C@@]([H])([C@@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])N(C(=O)[C@@]1([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H])[C@]1([H])N([H])C([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]O[C@]1(N(N=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C(=O)C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C([H])=C(N([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@](N([H])C(=O)[C@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=NC(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(OC3=NC(=NC(=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C3=C([H])C([H])([H])N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C2S1
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])N1N=C([H])C(C(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1SC([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C#CC2=C([H])C([H])=C(N([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C(C([H])=C(Br)C([H])=N2)C([H])([H])C([H])([H])C2=C1C([H])=C([H])C(Cl)=C2[H]
[H]N(C(=O)C([H])([H])SC([H])([H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N2C(=O)C([H])([H])N(C(=O)C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])C(=O)C1=NC2=C(S1)C([H])([H])C([H])([H])C2([H])[H]
[H]ON(C(=O)C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([C@@]1([H])C([H])([H])N(C#N)[C@@]([H])(C([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C(Br)C([H])=C([H])C(Br)=C1[H]
[H]N([H])C1=NC2=C(C(=O)C3=C([H])C([H])=C(C([H])=C23)C(=O)N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C(F)(F)C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1C([H])=C([H])C2=C([H])C([H])=C3N=C([H])C([H])=C([H])C3=C12
[H]N1C2=C([H])C([H])=C(C([H])=C2OC([H])([H])C1=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C(=C([H])C(=N1)C([H])([H])[C@@]1([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])C2=C(F)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C(C(=C([H])C(Cl)=C1[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2C(=NN3[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N1C(=O)N2N(C1=O)[C@@]([H])(C([H])=C([H])C2([H])[H])C(=O)N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1([H])[H])C([H])([H])SC1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C([H])C2=C(OC3=C2[C@@]2(C([H])([H])C([H])([H])[C@]3([H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C(Br)=C1O[H]
[H]N([H])C1=NN2C(=N1)C1=C([H])C([H])=C([H])C([H])=C1N=C2C1=C([H])C([H])=C([H])C([H])=C1Br
[H]C1=C([H])C([H])=C(OC([H])([H])C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=NC(=C([H])C([H])=C1N([H])C1=C([H])N=C([H])N=C1[H])C1([H])C([H])([H])C1([H])[H])C1=NN(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]2(O[C@@]([H])(OC([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C23)C1([H])[H]
[H]C1=C(F)N=C2C([H])=C3N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C2=C1C(F)(F)F
[H]C1=NN(C([H])=C1C1=NC([H])([H])C2=C1C(OC1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])=NC([H])=C2[H])[C@@]1([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C(OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C(=O)N([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])O1)(C([H])([H])[H])C([H])([H])[H]
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[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC(=O)C(\[H])=C(\[H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1O[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC(=O)C1=C([H])C([H])=C(S1)C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(C2=NOC(=C2N(C(=O)OC([H])([H])C2=C([H])N=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
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[H]N(\C([H])=C1/C([H])=C(Br)C(=O)C(OC([H])([H])[H])=C1[H])N1C(=S)N([H])N=C1C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N(C1=C([H])C([H])=C2N(C([H])([H])[H])C([H])([H])[C@](OC2=C1[H])(C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC(=O)C4=C([H])C(Cl)=C(N([H])[H])C([H])=C4OC([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
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[H]C([H])=C([H])C([H])([H])N(C(=O)OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C2=C(S1)C([H])([H])C([H])([H])C2([H])[H])C1=NC(=C([H])S1)C([H])([H])[H]
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[H]N1C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])N(C4=C([H])C([H])=C(Cl)C([H])=C34)C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])OC(=O)[C@]1([H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])[H])C(=O)[C@@]2([H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)O[C@]([H])(C3=C([H])OC([H])=C3[H])C([H])([H])[C@]21C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=NN1C([H])([H])C([H])([H])[H])C([H])([H])[H]
CC1=CC=C2OC(=O)N(CC3=CC=CC(O)=C3)C2=C1
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[H]N([H])C1=NOC2=C1C([H])=C(C([H])=C2[H])N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1F)N1C([H])=C([H])N=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC1=C(C([H])=C(C([H])=C1C([H])([H])[H])C1=NN([H])C(=O)C(=C1[H])C1=NC2=C([H])C([H])=C(C([H])=C2N1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(OC(=C2[H])C(=O)N([H])[C@@]2([H])[C@@]([H])([N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C([H])([H])C2=C([H])C([H])=C([H])N=C2[H])C([H])=C1[H]
[H]O[C@@]12C([H])([H])[C@]3(C(=O)[C@]4([H])OC5=C(OC([H])([H])[H])C([H])=C([H])C6=C5[C@@]14C([H])([H])C([H])([H])N(C([H])([H])C(=C([H])[H])C([H])([H])[H])[C@@]2([H])C6([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C3([H])[H]
[H]C1=C(SC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=C(N2N=C(OC([H])([H])[H])C(N(C3=C([H])N=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])[H])=C2S1)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]N(C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[C@]1([H])OC(C2=C([H])C([H])=C([H])C([H])=C2[H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C2=C([H])C([H])=C([H])C(=C2S1)[C@]1([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C1([H])[H])C([H])([H])[C@]([H])(O[H])[C@@]1([H])[C@]3([H])C([H])([H])C([H])([H])[C@]([H])([C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])C4=C([H])C([H])=C(C([H])=C4[H])S(=O)(=O)N([H])[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N(C(=O)C(C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
CC(C)N(CC1=CC=CC=C1)C(=O)CN1C2=C(C=CC=C2)N2C(=NN=C2C2=CC=CC=C2)C(NC2=CC=CC=C2)C1=O
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@@]12C([H])([H])C([H])([H])C(=O)[C@]3([H])OC4=C(OC([H])([H])[H])C([H])=C([H])C5=C4[C@]13C([H])([H])C([H])([H])N(C([H])([H])C1([H])C([H])([H])C1([H])[H])[C@]2([H])C5([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C(Cl)=C(C([H])=C12)[N+]([O-])=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C2=C(C([H])=C(C([H])=C2[H])C(=O)N([H])C([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])N(C1=O)C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]C1=C([H])C2=C(C([H])=C1F)C1=[N+](C3=C([H])C([H])=C(F)C([H])=C3C3=C([H])C(=C([H])C(N2C([H])([H])[H])=C13)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C#N)C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N1C(=O)C2=NC([H])=C([H])C([H])=C2C1=O
[H]\C(=N/S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C(\C([H])=N/N=C2\SC([H])([H])C(=O)N2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C(C#N)=C2[H])C([H])([H])C1([H])[H]
CC(C)(C)OC(=O)N1CCN(CC1)S(=O)(=O)C1=C(Cl)C=C(NC(=O)C=C)C=C1
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[H]N(C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C(C(=C1[H])N1C(=O)C2=C(N=C1C([H])([H])[H])C([H])=C([H])C(=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
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[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)O[H]
[H]N(C(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(O[C@]3([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])=NC(=C2[H])C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])C(=O)C([H])([H])N1C(Br)=C(N=C1C([H])([H])[H])[N+]([O-])=O
[H]C1=NC([H])=C([H])C(=C1[H])C1=NN2C(N=C([H])C([H])=C2C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])([H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])[C@]2([H])C3([H])[H])=C1C1=C([H])C(OC([H])([H])[H])=C(F)C([H])=C1[H]
[H]O[C@](C1=C([H])N(N=N1)C([H])([H])C1=C([H])C([H])=C2C(SC(C(=O)C([H])([H])[H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])(C([H])([H])C([H])([H])[H])C(F)(F)F
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C1=C(N([H])C(=O)N([H])[C@@]2([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C4C([H])=C(F)C([H])=C([H])C4=C3[H])C([H])([H])C2([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C1([H])[C@@]([H])(C(=O)O[H])[C@]1([H])C(=O)O[H]
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COC1=CC(=CC=C1)N1N=NC(C2CC2)=C1C(=O)N(C)C1=CC=C(C=C1)C#N
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CC(C)CNCC1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
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[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=NC([H])=NC2=C1N=C([H])N2[C@]1([H])O[C@]([H])(C([H])([H])N([H])C([H])([H])[C@@]2([H])C([H])([H])[C@]2([H])C(=O)OC([H])([H])C([H])([H])[H])[C@@]2([H])O[C@@]([H])(O[C@@]12[H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
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[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1Cl)C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(O[H])(C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C2=C3C(=C([H])C([H])=C12)C([H])([H])C([H])([H])N([H])C3([H])[H]
[H]O[C@@]([H])(C([H])([H])OC([H])([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
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[H]C1=[N+](C([H])=C(S1)C([H])([H])[H])C([H])([H])C1=C([H])C(OP([O-])(=O)OC2=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@]1([H])C2([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C2=NC(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(C1=C2N=C(N([H])C2=NC([H])=C1Br)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(N=N1)N([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])SC1=NC2=C(N=N1)C1=C(C([H])=C([H])C([H])=C1[H])N(C(=O)C([H])([H])[H])[C@@]([H])(O2)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C2C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C2C(=C1[H])[C@]([H])(N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C1=NC2=C([H])C(=C([H])C(=C2N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])[N+]([O-])=O)[N+]([O-])=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)OC1(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C([H])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C(=O)C([H])([H])[H])C(O[H])=C(C(O[H])=C1C(=O)C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C2N=C([H])N([H])C2=NC(=N1)N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C(OC([H])([H])[H])=C1[H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C3(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1=O)C([H])([H])O2
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[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=O)\C2=N\C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=C([H])N=C2C([H])([H])[H])C(=O)N([H])[H])C([H])([H])C1([H])[H]
NS(=O)(=O)C1=C(F)C(F)=C(C(F)=C1F)S(=O)(=O)CCO
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(\[H])=C2\C3=C([H])C([H])=C([H])C([H])=C3SC3=C2C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N(C(=O)C([H])([H])N(C(=O)[C@]3([H])N(C(=O)[C@]4([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[C@]([H])(O[H])C3([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])O[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]N(C(=O)C1=C(C([H])=O)N(C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C3=C(C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])=C(C(=NC1=O)N([H])C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N(C1=C(Cl)C(=C(Cl)C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])N2C(Br)=C(N=C12)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])C(=O)N(C([H])([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]([H])(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(N([H])C2=NC(=O)\C(S2)=C(/[H])C2=C([H])C([H])=C([H])S2)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)[C@]2([H])ON(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])[C@]2([H])C1=O
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[H]O[C@@](C(=O)N([H])C1=C([H])C2=C(C([H])=C1[H])C(=O)ON=C2C([H])([H])[H])(C([H])([H])[C@]1([H])C2=C(C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=NO1)C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)C2=C(C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C1=O
[H]N1C(=O)N(C2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])=NC([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2N(C([H])([H])[H])[C@]3([H])N(C([H])([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=C3C([H])=C([H])C([H])=C1[H]
[H]N(N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C([H])N2C([H])([H])[H])C1=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]\C(=C(/[H])[C@@]1([H])[C@@]2([H])N3C([H])([H])\C(=C(\[H])C4=C([H])C(Cl)=C(Cl)C([H])=C4[H])[C@]1([H])C([H])([H])[C@@]3([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
COC1=CC=C(C2=CC(=NN12)C(F)(F)F)C1=NN(CCCCOC2=CC=C(C=C2)C2=NNC(=O)CC2)C(=O)CC1C
[H]N1C([H])=C(C2=C1C([H])=C(F)C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N1C(=O)N([H])[C@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C1([H])[H]
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[H]N=C(N([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H]
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[H]C([H])=C([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C(\[H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
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[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C(F)C(F)=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])[H])C(=O)N([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]1([H])OC([H])([H])C2=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])SSC([H])([H])C3([H])[H])=C([H])C([H])=C2C1([H])[H]
[H]N(C1=C2N=C([H])N(\C([H])=C(/[H])C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C2=NC(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])P(=O)(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=NN=C(O2)N([H])C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=NN(C(=O)C2=C1C([H])=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])N(C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(C2=C([H])C([H])=C([H])O2)=C(F)C([H])=C1[H])C(F)(F)F
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C(N([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(C(=O)O[H])[C@]([H])(C2=C(Cl)C([H])=C([H])C([H])=C2[H])C(C(=O)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C(N1C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)C([H])([H])C([H])([H])S[H]
CCCCN1CCCC[C@H]1[C@H](C(=O)OC)c1ccccc1
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C1=NC(=NO1)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(N=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])C([H])=[N+]1[O-]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])N(C3=C(N([H])C(=O)C([H])=C3[H])C2=O)C([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2F)C([H])=C1[H]
[H]\C(=N/C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N2C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N1C(=NN=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=NC(=NC([H])=C3C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])N2C([H])([H])C([H])([H])C(F)(F)C2([H])[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])S(=O)(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1(N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2N([H])C(=O)N([H])C2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=NC([H])=C([H])N=C2N1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[C@@]1([H])O[C@@](OC([H])([H])C1([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C(N=C(S1)C1=C([H])N(C2=C(F)C([H])=C([H])C([H])=C12)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C1=NC(=NC(=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])C(F)=C(Br)C([H])=C1[H]
[H]C1=C2N(C(=O)C(=O)C2=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C(OC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C1=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N=C(O1)C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2O[C@]1([H])C1=C([H])C([H])=C(O[H])C(O[H])=C1[H]
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1F)C([H])([H])C1(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC3=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C(=O)N2C([H])([H])C2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])[C@]([H])(C1=C(N([H])C2=C1C([H])([H])N(C(=O)[C@]13C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C1([H])[H])C3([H])[H])C([H])([H])C2([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C(OC([H])([H])[H])=C(Cl)N=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(=O)N(C(=O)C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])N(C1([H])[H])S(=O)(=O)C1=NN(N=C1[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
CC1=C(C=CC=C1)C1=CN=C(N1)[C@@H]1CCCN1C(=O)COC1=CC=C(C=C1)C1=CC=CC=C1
[H]OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]N([H])C1=NC2=C([H])C(SC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C3=C([H])C2=C(C([H])=C3C([H])([H])[H])C([H])([H])[H])=N1
[H]N([H])C1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
COC1=CC(NC2=C3C=NN(C)C3=NC(=N2)N2CC(C)OC(C)C2)=CC=C1
OC(CNC1CCN(CC1)C1=NC=NC2=C1C(=CS2)C1=CC=CC=C1)COC1=CC(O)=CC=C1C(O)=O
FC1=CC=CC=C1NC(=O)NC1CCN(CC2=CC=C(C=C2)C2=NN=C3N2C2=CC=CN=C2NC2=C3C=CC=C2)CC1
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C(OC([H])([H])[H])C([H])=C([H])C2=C([H])C3=[N+](C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C31)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
COC1=C(C=CC=C1)C1=CN2C(=N1)N=C(C)C(CN)=C2C1=CC=C(Cl)C(F)=C1
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[H]N(C(=O)C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C1=NC(=C([H])C([H])=N1)C1=C2C([H])=C([H])C([H])=NN2N=C1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]C1=C(N2C([H])=C([H])C(N3C([H])([H])C([H])([H])N(C4=NC([H])=C([H])C([H])=N4)C([H])([H])C3([H])[H])=C(C#N)C2=N1)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(\C([H])=C(/[H])C2=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])=C1[H]
[H]C([H])([H])C([H])([H])OC1=NO[C@@]2(C1([H])[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2([H])[H])[N+]1(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(Br)=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])OC([H])([H])[H])=C(OC([H])([H])OC([H])([H])[H])C([H])=C12
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[H]OC1=C([H])C2=C(O[H])C(=C1[N+]([H])([H])C([H])([H])C([H])=C([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(OC([H])([H])[H])[C@]([H])(O[H])[C@]([H])(\C([H])=C(C([H])([H])[H])\[C@]([H])(OC(=O)N([H])[H])[C@@]([H])(OC([H])([H])[H])\C([H])=C(\[H])/C(/[H])=C(/C(=O)N2[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N(C1=C([H])C([H])=C([H])C(\C([H])=C(/[H])C(=O)OC([H])([H])[H])=C1[H])C([H])([H])C1=C([H])C([H])=C(\C([H])=C(/[H])C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])C([H])=C2C3=C4C(N([H])C([H])=C4C([H])([H])[C@@]2([H])N(C([H])([H])[H])C1([H])[H])=C([H])C([H])=C3[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=N[C@]([H])(N(C(=N1)N([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]2(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])N(C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
FC1=CC(NC(=O)C2=CC=CN(C3=CC=C(C=C3)C(F)(F)F)C2=O)=CC=C1OC1=NC=NC2=C1N=CN2
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])=C(C2=C([H])C([H])=C(OC([H])([H])[H])N=C12)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1N=C(C#N)C(=O)N(C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C2=C([H])C(=C(Cl)C([H])=C2[H])C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])[C@]2([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]ON(C(=O)N([H])[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])C1([H])[H])C([H])=C([H])C(OC1=C([H])C([H])=C([H])C([H])=C1[H])=C2[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])SC1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2SC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(\C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])=C(\C([O-])=O)C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(C1=NN([H])C(=S)S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])C([H])(N([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C(Cl)=C(Cl)C([H])=C1C(=O)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NC(=NO1)C1=C([H])N=C([H])N=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(C#N)C([H])=C(C([H])=C1C#N)C1=NN=C(S1)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C([H])([H])C([H])([H])OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(C([H])=O)=C(N=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
CC1=CC(NC(=O)\C=C\C2=CC(O)=C(O)C=C2)=CC=C1
[H]N(C1=NC([H])=C([H])C(=N1)N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C#N)C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(N2SC3=C(C([H])=C([H])C(F)=C3[H])C2=O)=C(C(Cl)=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(OC([H])([H])[H])=C([H])C(=N1)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N(C([H])=O)C2=C([H])C([H])=C([H])C([H])=C12
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=N1
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C(=C([H])C([H])=C1I)C(=O)O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])OC(=O)C([H])([H])[H]
[H]N([H])C1=NN([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])C(=NC(=N1)N([H])[H])N1C([H])([H])[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C(=O)N(C(=N2)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])N(N=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(=C([H])C(N=[N+]=[N-])=C2[H])C([H])([H])N=[N+]=[N-])C([H])=C1[H]
ONC(=O)C1=CC=CC(F)=C1S(=O)(=O)N1CCC(CC1)OC1=CC=C(C=C1)C(F)(F)F
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C2C([H])=NN1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])C(=O)C1=C(N([H])[H])N(N=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C(=O)C1=C([H])C([H])=C2SC3=C([H])C([H])=C([H])C([H])=C3C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C(C([H])=O)N12
[H]OC([H])([H])C(N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[C@]2([H])N([C@@]([H])(C([H])([H])OC2([H])[H])C2(C([H])([H])[H])C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2OC([H])([H])OC2=C([H])C(=C1[H])C([H])([H])[C@@]1([H])C(=O)OC([H])([H])[C@]1([H])C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]O[C@]([H])(C([H])([H])N=[N+]=[N-])[C@@]([H])(O[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(C#N)=C2C3=C1C([H])=C([H])C([H])=C3C(=O)N([H])C([H])([H])C2([H])[H]
[H]N([H])C1=C(N([H])C2=C([H])C([H])=C(C(=O)C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C(Cl)=C2[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C([H])S1)C(=O)C(F)(F)F)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(ON=C1C([H])([H])C([H])([H])[H])[C@@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(I)=C2[H]
[H]OC1=C(N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])\C(=N\C2=C(O[H])C(=C([H])C([H])=C2[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=O
[H]N([H])S(=O)(=O)C1=C([H])C2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])SC([H])([H])C2([H])[H])S1
[H]C1=C([H])C([H])=C(C2=NN=C3SC([H])([H])C(=NN23)C2=C([H])C(OC([H])([H])C3([H])C([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])[C@]([H])(C2=NN3C([H])=C([H])C([H])=C3C(=O)N2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])N1C2=C([H])C([H])=C([H])C(C3=C([H])C(OC(F)(F)F)=C([H])C([H])=C3[H])=C2OC([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H])C(F)(F)F
[H]OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])[N+]([H])([H])C([H])([H])C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C1=C(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])F
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[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(C#N)C([H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C([H])C(=N1)C([H])([H])SC1=C(Cl)C([H])=C([H])C([H])=C1Cl
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[H]C1=C(N(C2=NC3=C(N12)C(=O)N(C(=O)N3C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])N=C([H])N=C2C(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
COC(=O)C1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
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[H]N(C(=O)C([H])([H])OC(=O)C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)\C(=C(\[H])C1=C([H])C([H])=C([H])O1)C([H])([H])C2([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
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[H]O[C@]([H])(C1=C([H])N=C([H])N1C([H])([H])[H])C1=C2C(=NC3=C(C([H])=C(Cl)C([H])=C13)C([H])([H])[H])N([H])N=C2C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N(C1=C([H])C(OC([H])([H])C(=O)OC([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])C(F)(F)F
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[H]OC1=C([H])C([H])=C(\C([H])=C(/C#N)C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])=C1[H]
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[H]C([H])=C([H])C([H])([H])N1C(=O)N(C2=C(N(C(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])Cl)C1=O)C([H])([H])[H]
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[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=NC(=NC(=C1[H])C([H])([H])[H])N(C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1Br)C([H])([H])C([H])([H])[H]
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[H]O\C(OC([H])([H])C([H])([H])[H])=C1\C(=NC(=C(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N1C(=O)C2=C(N=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1S2)C([H])([H])[H]
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[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C([H])=C(F)C([H])=C1F)[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H]
[H]O[C@]1([H])OC([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])OC1=C([H])C2=C(SC3=C(N2[H])C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C1(N2C([H])([H])C([H])([H])N(C(=O)[C@@]3([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[C@]3([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C2C(=O)[C@]([H])(C([H])([H])OC(=O)C3=C(Cl)C(=C([H])C([H])=C3Cl)S(=O)(=O)N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])S(=O)(=O)C2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
COC1=C2N=C(NC(=O)C2=CC(=C1)C1=CNN=C1)C(N)C1=CC=CC(Cl)=C1
[H]N([H])C(=S)N1N=C(C2=C([H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])N=C2C([H])=C([H])N(C2=C1[H])S(=O)(=O)C1=C(Cl)N=C2SC([H])=C([H])N12
[H]N(C(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H][C@@]1(CCCCN1CC1=CC=C(C=C1)[N+]([O-])=O)[C@H](C(=O)OC)C1=CC=CC=C1
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(OC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(N([H])[H])C(=C1[H])C([H])([H])N1C(=O)[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C3=C(S2)C([H])=C([H])C(OC([H])([H])[H])=N3)C([H])([H])C1([H])[H]
CN1C=C(C=N1)C1=CC=C(CN2C(=O)C(O)(C3=CC=CC=C23)C(F)(F)F)C=C1
[H]N(C1=C([H])C(=C([H])C2=NC([H])=C(N=C12)N1C([H])([H])C([H])([H])C([H])(OC([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=NN=C2C([H])=C([H])C(=NN12)C1=C([H])C([H])=C(F)C([H])=C1[H]
COC1=CC=C(C=C1)C1=CSC(NN=C2CCCCCC2)=N1
[H]OC(=O)[C@@]([H])(N([H])[C@]([H])(C(=O)N1C(=O)N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)O[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC(=O)C2(C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2S(=O)(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H]
[H]OC1=C(C([H])=C([H])C([H])=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)N([H])C1=C(F)C([H])=C([H])C([H])=C1F)C1=C([H])C2=C([H])N=C([H])C([H])=C2N1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C([H])C2=C([H])C([H])=C(N=C12)C1=NN=C2C([H])=C([H])C([H])=C([H])N12
[H]OC([H])([H])C([H])([H])C([H])([H])[C@]1(OC(=O)N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC3=C(C(=N2)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N=C1S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C(Cl)=C([H])C([H])=C2[H])C(=O)N1C1=NC([H])=C([H])S1
[H]N1C(=O)N(C(=O)C(=C1N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=N/C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N(C([H])([H])[H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])\N([H])[N+]([O-])=O
[H]N(N([H])S(=O)(=O)C([H])([H])[H])C(=O)C(N([H])C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=N/C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C(N(N=C1C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=NS2)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2N=NC3=C(C([H])=C([H])C([H])=C3[H])C2=O)C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=C2C([H])=C([H])C([H])=C(C2=NC(=C1[H])C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N2C(=O)C(Br)=C(OC([H])([H])C3=C(F)C([H])=C(F)C([H])=C3[H])C([H])=C2C([H])([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(Br)=C([H])C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C(=C([H])C(=O)O2)C([H])([H])[H]
NC1=NC(N[C@H]2CCNC2)=C2C=C(NC2=N1)C1=CC=C(F)C=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C2=C(C3=C([H])C([H])=C([H])C([H])=C3N2S(=O)(=O)C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])O[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])C2=C1[H]
[H]N(C(=O)C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H])C1=C(N([H])C2=C1C([H])=C([H])C(=C2[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
CN1CCCC1CCNC(=O)C1=C(N)C2=C(C)C(Cl)=C(C)N=C2S1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@@]([H])(N1C(=O)SC([H])([H])C1=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2N=C([H])C(=O)N([H])C2=O)[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])SC(C(=O)N([H])C2=C(C([H])=C(Cl)C([H])=C2[H])C(=O)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1Cl
[H]OC1=C(C(=O)O\C1=C(\[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=C(/[H])C([H])([H])C([H])([H])C1=C([H])OC(=C1[H])C([H])([H])C1=C([H])OC([H])=C1[H])\C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=O)C(=O)C2=C([H])C(OC(F)(F)F)=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)N=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])C(=O)C(N([H])C(=O)C2=C([H])C3=C(C([H])=C2[H])C(=C(N3C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=N2)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])OC1=C2OC([H])([H])C([H])([H])C([H])([H])C2=C([H])C(F)=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
Br.CN(C)CCCC1(OCC2=C1C=CC(=C2)C#N)C1=CC=C(F)C=C1
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1SC([H])([H])C([H])([H])C([H])([H])N1C([H])=NC(=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=NC([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C21)[C@@]1([H])C(=C([H])C([H])=C([H])[C@]1([H])C#N)C([H])([H])[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2N=NC(=N2)C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C(O[H])=C1[H])[C@@]1([H])OC2=C(C(O[H])=C([H])C(O[H])=C2[H])C(=O)C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=NN(N=N1)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])C([H])([H])OC(O[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C1=NC(=NC(N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C(F)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(Br)=C([H])C2=C1OC(=C([H])C2=O)C1=C([H])C([H])=C([H])C(\C([H])=C(/[H])C2=NC3=C(C([H])=C([H])C([H])=C3[H])C([H])=C2[H])=C1[H]
[H]N(C1=C([H])C(Cl)=C2C(=O)N(C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N([H])C1=C(C(=O)OC([H])([H])C([H])([H])[H])C2=C(S1)C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C1=NC([H])=C(C([H])=C1[N+]([O-])=O)[N+]([O-])=O)C([H])([H])C1=C([H])C2=C(OC(=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])[H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2(C1=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])[C@@]([H])(C2([H])[H])[C@]1([H])C([H])([H])[H]
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[H]N1C2=C([H])C([H])=C3C4=C(C([H])=C(Br)C([H])=C4[H])C([H])([H])C3=C2C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]SC1=NN=C(S1)N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=N1
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C(/C#N)C(=O)N([H])[H])C([H])=C1C([H])([H])SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C([H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C([H])C([H])=C([H])N=C12)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(N1N=NN=C1[H])C1=C(SC([H])([H])[H])N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(N=N1)C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C3C(=C([H])C(=O)C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]2([H])[C@]2([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C(=O)C3([H])C([H])([H])C3([H])[H])[C@@]2(C([H])([H])[H])C1([H])[H]
[H]O[C@@]1([H])C2=C(N([H])C([H])=NC1([H])[H])N(C([H])=N2)C([H])([H])C([H])([H])C([H])([H])C#N
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C2C3=C(N=C(C([H])=C3N(C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])N1C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C(=C1[H])N(C([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC([H])([H])C([H])([H])N1N=NN=C1[C@]([H])(N([H])C(=O)C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(F)(F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC2=C(N3C([H])([H])C([H])([H])N(C([H])([H])C4=NOC(=C4[H])C([H])([H])[H])C([H])([H])C3([H])[H])C(Br)=C([H])N=C12)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[N+]([O-])=O)C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])=C([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C(=O)OC([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)OC([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])N2N=C([H])C(=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])[C@@]([H])(N2C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=O)C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)C([H])=C(C2=C1C(F)=C([H])C([H])=C2[H])C([H])([H])N(C(=O)C1=NC([H])=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])[C@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C(Cl)C(=C(Cl)C([H])=C1[H])C([H])([H])OC1=C2N=C(C([H])=C(C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1(C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C(=O)N([H])[C@@]2([H])[C@@]3([H])C([H])([H])[C@]4([H])C([H])([H])[C@]([H])(C3([H])[H])C([H])([H])[C@@]2([H])C4([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2C(=C([H])C(=C1[H])C([H])([H])[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=NN=C(N2C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=C(F)C(F)=C(F)C(F)=C1F
[H]N1C(=NC2=C1C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C21)C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N(N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H])C1=NC(=O)C([H])([H])S1
[H]OC(=O)C([H])([H])C([H])([H])OC1=C(C#N)C(N([H])[H])=C([H])C(=N1)N([H])C(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12
[H]N=C(N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C([H])([H])C([H])([H])[H])C(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=NOC([H])=C1[H]
[H]C([H])=C(C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)C1([H])[H]
[H]C1=C([H])N=C(S1)C1=NN(C([H])=C1[H])C1=C2C(=NC([H])=C1[H])N(C1=C([H])C([H])=C(C([H])=C1S(=O)(=O)C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C1=NC(N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(C#N)C(=N1)N([H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=NN1C([H])([H])C([H])([H])[H]
[H]O[C@]([H])([C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])OC(=O)N(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1F)C1=NN([H])C(N([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[H])=C1[H]
FC(F)(F)OC1=CC=C(C=C1)C1=CN(N=N1)C1=CC=C2OS(=O)(=O)C=CC2=C1
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])[C@@]1(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[N+]([H])([H])[H]
[H]N1C(C(=O)OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C(C2=C1C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])O1)C([H])([H])C2=O)C([H])([H])[H]
[H][C@]12CN(C)Cc3cccc(Cc4c(O)c(O)ccc14)c23
[H]N(C(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C(=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])ON([H])C(=O)C1=C2N(C(=O)C(F)=C1N([H])C1=C([H])C([H])=C(I)C([H])=C1F)C([H])([H])C([H])([H])C2([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC3=C(N=C([H])N3C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(=N2)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N2C(SC3=C([H])C([H])=C(F)C([H])=C3[C@]([H])(N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])O[C@]([H])(C([H])([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
OC(=O)C1CCN(CC1)C1=CC2=C(OC(=N2)C2=CC=C(C3=CC=CC=C3)C(=C2)C(F)(F)F)C=C1
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=NC(=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C2=C3OC(=NC3=C([H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C2=C(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3OC2=O)C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])OC([H])([H])[C@]12C([H])([H])[C@@]1([H])[C@@]([H])(N1C([H])=NC3=C(N=C(Cl)N=C13)N([H])C([H])([H])[H])C([H])([H])[C@@]2([H])OP(=O)(O[H])O[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(Cl)=C([H])N=C1N([H])C(=N[H])N([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])N1C([H])=C([H])\C(=N/C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C1C([H])=C(Cl)C([H])=C2[H]
[H]N(C(=O)C1=NSC([H])=C1N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N([H])C(=O)C1=C(C2=C([H])C(=C([H])C([H])=C2N1[H])S(=O)(=O)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[C@]2(SSC1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])[H])N([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=O)N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C1=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
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[H]N([H])C1=NC([H])=C([H])C2=C1C(=C([H])S2)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(Br)C([H])=C1\C([H])=N\N([H])C(=O)[C@@]([H])(SC1=NN=C(N1C([H])([H])C([H])=C([H])[H])C([H])([H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C1=C2C([H])=C([H])C([H])=C([H])C2=NC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C([H])=C([H])C(Cl)=C([H])C2=NC2=C1[C@]1([H])C([H])([H])C(=C([H])[C@]([H])(C2([H])[H])C1([H])[H])C([H])([H])[H]
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[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N=[N+]=[N-])C([H])=C1[H]
[H]OC1=C(C([H])=C2C([H])=C3C([H])=C([H])C([H])=C([H])C3=C([H])C2=C1OC([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(N([H])C(=N[H])N([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(N([H])C(=O)C3=C(O[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])=C1O[H]
[H]C1=C([H])C([H])=C(C(=N1)C([H])([H])[H])[C@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
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[H]N(C1=C([H])C2=C(C([H])=C1[H])C([H])=C([H])C1=C(C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H])S(=O)(=O)C([H])([H])[H]
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[H]N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C([H])C(N([H])C(=O)C4([H])C([H])([H])C4([H])[H])=C3[H])C([H])([H])[C@]12[H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
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[H]N(C(=O)C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[N+]2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]OC([H])([H])[C@@]1([H])N([H])[C@@]([H])(C2=C([H])N([H])C3=C2N=C([H])N([H])C3=O)[C@]([H])(O[H])[C@]1([H])O[H]
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[H]\C(=C1\C(=NN=C1C(F)(F)F)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
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[H]C1=C(C2=C([H])C(=C([H])C([H])=C2N1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=NC([H])=C([H])C([H])=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C#N)C([H])([H])C1([H])[H]
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NC1=C2C(SC=C2C2=CC(NC(=O)C3=CC=CC=C3)=CC=C2)=C(C=N1)C1=CN=CC=C1
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[H]N(C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1OC1=C([H])C([H])=C(Cl)C([H])=C1OC([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
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[H]OC1(C(=O)N([H])C(=O)N([H])C1=O)C([H])([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
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[H]S\C(=N/N=C(\[H])C1=C([H])C([H])=C([H])N1S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
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[H]N(C([H])([H])C1=C([H])C2=C(N([H])C1=O)C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
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COC1=CC2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=CC=C(CC(N)=O)C=C3)C2=O)C=C1
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[H]N([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@]([H])(C1=NN2C([H])=C(Cl)C([H])=C2C(=O)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
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[H]N(C1=NC2=C(C([H])=N1)C([H])=C([H])C(=O)N2C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
CCCCCCCN(CC1=CC=C(C=C1)N(CC)CC)S(=O)(=O)C1=CC=C(Cl)C=C1
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1OC1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C2=C(OC1=O)C([H])=C(C([H])=C2[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1N=C(C(=O)N([H])C2([H])C([H])([H])[C@@]3([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])C3([H])[H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
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[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])N=C1[H]
[H]C([H])([H])C1(C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(Cl)=C([H])N=C(N([H])C([H])([H])C(F)(F)C2=[N+]([O-])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[H]
[H]N1C(=O)N([H])C(N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C(C1=O)C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC1=NSN=C1O[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C(=O)N([H])C([H])([H])C2=NN=C(S2)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(OC2=C(F)C([H])=C([H])C([H])=C2[H])C([H])=C1C(=O)N([H])C1=NC(=C([H])S1)C([H])([H])[H]
[H]C1=NC(=C(C([H])=C1[H])[C@@]([H])(C#N)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[C@@]([H])(N(C(=O)OC([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C(OC2=C([H])C([H])=C([H])C([H])=C12)C(=O)C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H]
[H]N([H])C(=O)[C@@]1([H])[C@]2([H])C([H])=C([H])[C@@]([H])(C2([H])[H])[C@@]1([H])N([H])C1=NC(=NC([H])=C1Cl)N([H])C1=C(OC([H])([H])[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C2=NC(=NC([H])=C2[N+]([O-])=O)N([H])C([H])([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])[C@]([H])(O[H])[C@]([H])(O[C@@]1([H])N1C([H])=NC2=C(N=C(Cl)N=C12)N([H])OC([H])([H])[H])C1=NOC([H])=C1[H]
[H]C1=C([H])C2=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C(=C3Cl)C(F)(F)F)C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2N1C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@@]([H])(N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C2SC(=C3[H])C2=C([H])N(C([H])=N2)C([H])([H])[H])C(F)=C1[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NOC3=C2C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(O[C@@]([H])(C(=O)N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])=C([H])C(=O)OC2=C1[H]
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[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C(N=C1C1=C([H])C([H])=C([H])N=C1C([H])([H])[H])C(F)(F)F
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C2N(C3=C(C([H])=C([H])C([H])=C3[H])C2=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])\C(=C(\[H])C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])N=C23)C2=C([H])C([H])=C(F)C([H])=C12
[H]OC(=O)C1=C([H])N(N=C1[H])C1=NC([H])=C(C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=O)C([H])([H])C([H])([H])[H])C(=O)SC2=C([H])C(=C1[H])C(=O)C([H])([H])C([H])([H])[H]
[H]N1C(=C([H])C2=NC(=NC(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C12)C([H])([H])[H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2OC([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C2=NOC(=N2)C2=C(C([H])=C([H])C([H])=C2F)C2=C([H])C(Cl)=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NN1C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C(Cl)C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(C(=O)N([H])C([H])([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])=C(Cl)C([H])=C1[H]
[H]N1C([H])([H])C2=C([H])N=C([H])N2C([H])([H])C2=C([H])C(OC3=C([H])C4=C(C([H])=C([H])C([H])=C4C([H])=C3[H])N(C(=O)C1([H])[H])C([H])([H])[H])=C(C#N)C([H])=C2[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(\[H])=C2/C(=O)N([H])C3=C([H])C([H])=C([H])C(C(=O)OC([H])([H])C([H])([H])[H])=C23)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=NN(C(=O)C([H])=C2[H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2Cl)[C@]([H])(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
CN(C)C1=CC(=CC(COCC2(CCNCC2)C2=CC=C(F)C=C2)=N1)C(F)(F)F
[H]N([H])C1=NC(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
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[H]OC(=O)C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])SSC([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])O[H]
[H]C1=C([H])C2=C(C([H])=C1[H])[C@]1([H])N(C([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C13)C([H])([H])C2([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC2=C(S1)C([H])=C(C([H])=C2[H])C(=O)N([H])C1=C(Cl)C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(C2=C([H])N=C(N=C2[H])C2=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C(C#N)=C2[H])=C1C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=C([H])C2=C1C1=C([H])C([H])=C([H])C([H])=C1N2[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C(O[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@]1([H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])C2(OC3=C(C(=C([H])C([H])=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]OC(C1=C([H])N=C(S1)N(C(=O)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])(C(F)(F)F)C(F)(F)F
[H]N(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])S1)C(=S)N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]C1=C([H])C([H])=C(\N=C2\SN(C(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@]1([H])C1=C([H])N([H])C([H])=N1
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[H]N(C(=O)C([H])([H])[H])C1=NC2=C(OC3=NC(=NC(=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)N([H])C([H])([H])[C@]3([H])N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C2S1
[H]N(C1=NC([H])=C([H])N2C1=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C(C2=C(N([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C1=C(C#N)C([H])=NC([H])=C1\C([H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])OC(=O)N2C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C(OC([H])([H])[H])C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C4=C(C([H])=C([H])[N+]([O-])=C4[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3OC([H])([H])C([H])([H])OC3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N(C1=NC(=NC([H])=C1[H])N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1I)[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])[C@@]2([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3OC2([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C1=NC(=C([H])S1)C([H])([H])C1=NN=C(S[H])N1N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C([H])C(=O)O1
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(=O)N1C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])[C@]([H])(C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(O[H])C([H])([H])O[C@]1(C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])C1=C([H])N(C2=C1C(F)=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=N1)N1C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])[H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(SC2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C2[H])C(=C1[H])C(F)(F)F
[H]C1=C(OC([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=C(OC2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])N=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=C(C([H])=C(Cl)C([H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C([H])C(Br)=C([H])C([H])=C12
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[H]C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C(=C([H])C(Cl)=C1OC([H])([H])[H])C1=C([H])C(F)=C(F)C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=NC(=NC2=C1C([H])=C(N2C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])=NC2=C1C([H])=NC([H])=C2[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1N1C(=O)N(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
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[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
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[H]N(C1=NC(=C([H])C([H])=N1)C1=C2C([H])=C([H])C([H])=NN2N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC(=O)C1=C([H])C([H])=C([H])C2=C1N(C([H])=C(C(=O)N([H])C1=C([H])C([H])=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C(=C1[H])C(F)(F)F)C2=O)C([H])([H])[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N([H])C([H])([H])[C@@]1([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C(Cl)N=C(C(=O)OC([H])([H])[H])C(=N3)N([H])[H])C([H])([H])[C@@]2([H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])[C@@]([H])(N(C([H])([H])[C@@]1([H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(I)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)N([H])[C@]([H])(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C(F)C([H])=C2C(N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2=O)=C1[H])C(C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O\N=C1\C(\N([H])C2=C\1C([H])=C([H])C([H])=C2[H])=C1\C(=O)N([H])C2=C([H])C(I)=C([H])C([H])=C12
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C1=C([H])C2=C(OC(=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=C2C(=N1)N(C(=O)C(=C2C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])C2=C([H])C([H])([H])[C@]3([H])[C@@]4([H])C([H])([H])C([H])=C(C5=C([H])N=C([H])N=C5[H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C([H])=C(Br)C(F)=C1[H])C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1Cl)[C@@]([H])(N1N=C([H])N=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C(C#N)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C(C(OC([H])([H])C([H])([H])OC2=NC([H])=C(Br)C([H])=N2)=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O\C(OC([H])([H])[H])=C1\C(=NC(=C(C(=O)OC([H])([H])[H])[C@@]1([H])C1=C([H])C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@](C([H])([H])N([H])C(=O)C1=C(N([H])[H])N(N=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])N(C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])[H])C(F)(F)F
Cc1cnc(NC2(CO)CC2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C([H])N=C2OC2=C1C([H])=C([H])C([H])=C2[H])C1=NN=C([H])S1
[H]OC1=C(Cl)C([H])=C(Cl)C([H])=C1S(=O)(=O)N([H])C1=C([H])C([H])=C(N2N=C(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(Cl)=C2C([H])([H])[H])C(=C1[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C(=C([H])C([H])=C2N=C(C2=C([H])C([H])=C([H])C(=C2[H])C2=C([H])OC(=N2)C([H])([H])[H])C([H])([H])C1=O)C(F)(F)F
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[N@@+]12C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])[C@@]([H])(OC(=O)C1([H])C3=C(OC4=C1C([H])=C([H])C([H])=C4[H])C([H])=C([H])C([H])=C3[H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])OC([H])([H])C([H])([H])C([H])([H])O1
[H]OC(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C2=C([H])C3=C(C([H])=C2[H])C(=O)C(=O)C2=C3C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([C@@]([H])(C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C(=O)N([H])S1(=O)=O)S(=O)(=O)C1=C(F)C([H])=C([H])C([H])=C1F
COCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC1=CC=CC=C1)NC(=O)OCC1=CC=CC=C1)B1O[C@@H]2CC3CC(C3(C)C)[C@]2(C)O1
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N2N=C(C3=C([H])N=C(N=C23)N([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])[H])C([H])([H])N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]\C(=C(\[H])C1=[N+](C2=NC3=C([H])C([H])=C([H])C([H])=C3N=C2N1C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])\C(\[H])=C1/N(C2=C(C([H])=C([H])C([H])=C2[H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[N+]([O-])=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C(F)(F)F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C(O[H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C2N=NN=C2N=C2SC([H])([H])C([H])([H])N12
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(F)C(=C([H])C([H])=C1[H])C1=C(N(C(=O)N(C1=O)C([H])([H])[C@]([H])(N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1F)C(F)(F)F)C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C3=C([H])C([H])=C(O[H])C([H])=C3[H])C([H])([H])SSC1([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]C1=C(ON=C1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=C([H])C(C2=C3N(N=C2C2=C([H])C([H])=C([H])C(=N2)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])=C2C([H])=C([H])C([H])=C([H])C2=N1
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C(F)C2=NC(=C([H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N([H])C2=C([H])C([H])=NN2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)O[C@@]1([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
COCC(=O)CC1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
[H]C1=C([H])C(=C([H])C(Cl)=C1[H])C([H])([H])OC1=C([H])C([H])=C2C(OC(=O)C([H])=C2C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])[C@]2([H])C([H])([H])N(C(=O)C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C(N([H])C(=O)C([H])=C2[H])C1=O)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1F)C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C(C(OC2=C([H])C([H])=C(C#N)C([H])=C2[H])=C(N1C([H])([H])S(=O)(=O)C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=NC2=C(S1)C([H])=C(OC([H])([H])C([H])([H])OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C([H])=C2[H]
CSC1=CC=C(OC2=C(Cl)C=NN(CC3=CC=CC4=CC=CC=C34)C2=O)C=C1
[H]C1=C([H])C(Cl)=C(C(Cl)=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])([H])[C@@]2([H])C([H])([H])[C@]1([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=NC(=NC2=C1[H])C1=NC([H])=C([H])C([H])=C1[H]
NS(=O)(=O)C1=CC2=C3N(C(=NC3=C1)C1=CC=CC=C1O)C1=CC=CC=C1O2
[H]N(C1=C(N([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(=O)C1=O)C1=C([H])C([H])=NC(=C1[H])C1=C([H])SC([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])O[C@@]2([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])=C(C2=NOC3=C2C([H])=C([H])C(F)=C3[H])C([H])([H])C1([H])[H]
[H]N1C(=NC([H])([H])C1([H])[H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(F)=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(OC([H])([H])C([H])([H])C([H])([H])[H])=NC3=C1C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])C2([H])[H]
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[H]N(C1=C2C([H])=C([H])C([H])=C([H])C2=NC([H])=N1)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(O2)C([H])([H])N([H])C([H])([H])C([H])([H])N2C(N([H])C([H])([H])C2([H])[H])=C(C#N)C#N)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C([H])=C2N3N=NC4=C([H])C([H])=C([H])C([H])=C4C3=NC2=C1[H]
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[H]C1=C([H])C([H])=C(SC([H])([H])[C@@]([H])(C(=O)C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(O[H])(C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C(\[H])=C(/[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C2SC([H])([H])C([H])([H])C([H])([H])C3=C2C(=C([H])C([H])=C3OC([H])([H])C2=C([H])C([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])N(C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C(N=C3[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C2=C1N([H])C1=C2C2=C(C(=O)N([H])C2=O)C2=C1C([H])=C([H])C1=C2N(C([H])=C1[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C(=C1[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])C([H])([H])[H]
[H]C1=C(N(C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(O[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)N([H])C(=O)C(N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C(I)=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])(C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)[C@@]1([H])N([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])SC([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])N([H])C(=O)C1=C(O[H])C2=C(C([H])=C([H])C(=C2[H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])N(C1=O)C([H])([H])[H]
CCS(=O)(=O)C1=CC2=C(C=C1)C(=O)N(C=N2)[C@@H](CC1CCCCO1)C(=O)NC1=NC=C(F)S1
[H]N(C(=O)[C@]1([H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])[H])C(=O)[C@@]2([H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)O[C@]([H])(C3=C([H])OC([H])=C3[H])C([H])([H])[C@]21C([H])([H])[H])C([H])([H])C([H])([H])C#N
[H]C1=C([H])C(OC([H])([H])C([H])([H])F)=C(OC([H])([H])[H])C(=C1[H])C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(C2=C(C([H])=C1[H])C(=NO2)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C(=O)O[C@]1([H])C2=C([H])C(=O)C(SC([H])([H])[H])=C([H])C([H])=C2C2=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
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[H]OC(=O)[C@]1([H])N(C(=O)C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(C(OC3=C([H])C([H])=C(N([H])[H])C([H])=C3[H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)[C@]1([H])N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C2C([H])=C(N(C(=O)C3=C([H])C([H])=C(OC([H])([H])C([H])([H])OC4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C2=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N(C(=O)C(F)(F)F)C([H])([H])C([H])([H])C2=C([H])C(O[H])=C([H])C([H])=C12
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N([H])C1=N[C@@](C(=O)N1C([H])([H])[H])(C1=C([H])SC([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=C([H])N=C1[H]
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C(F)(F)F)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C#N)C(=O)N([H])\N=C(/[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C(=C1[H])C(=O)C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])O[C@]1([H])O[C@]([H])(C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]1([H])O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)N([H])N([H])C(=O)C1=C([H])C(N([H])C(=N[H])N([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])N1C(=NC(=C1C(=O)OC([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]1=C(C([H])=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N2C(=N1)C([H])([H])C(=NC1=C([H])C(Cl)=C(Cl)C([H])=C21)C1=C([H])C([H])=C(C([H])=C1[H])N1C(=NC2=C1C([H])=C([H])N=C2[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C([H])C(=C([H])N2C([H])=C1C1=C([H])C([H])=C([H])C(Cl)=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N=C(O1)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)C(C2=C(F)C(=C([H])C([H])=C12)C1=C([H])C([H])=C(C#N)N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C(Cl)=C([H])N=C(N([H])C([H])([H])C(F)(F)C2=[N+]([O-])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C1=C(C([H])=C([H])C([H])=C1F)C(F)(F)F
[H]OC([H])([H])C([H])(N(C(=O)C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C([H])=C2N1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])O[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@@]2(C1([H])[H])C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])[N+]([H])([H])[H])C([H])([H])C1=C([H])N([H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])OC(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])[C@]1([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=C(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C2C(=C([H])C(Cl)=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C([H])([H])[H])[C@]1([H])C([H])([H])C2=C([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])[C@]5([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[C@]45C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])[C@]1([H])C(=O)N([H])C(=O)[C@@](OC2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C(F)=C3[H])C([H])=C2[H])(C1=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]N1C2=C([H])C3=C(C([H])=C2C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C(=C([H])C(=O)N3C([H])([H])[H])C(F)(F)F
[H]N1C(=O)C([H])([H])C([H])([H])C2=C1N=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C4C(OC([H])([H])C([H])([H])C4([H])[H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])=C2[H]
[H]N(C(=O)C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C1=C(C(=C([H])C([H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(OC2=C([H])C(Cl)=C(C#N)C([H])=C2[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1N=NC(=N1)C1=C([H])N=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])[H])C(=C([H])C([H])=N2)C([H])([H])[H]
[H]N([H])C1=NC2=C(N=C([H])N2C([H])([H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])C(=N1)C1=C([H])C([H])=C([H])O1
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C3=C([H])C([H])=C(O[H])C([H])=C3[H])C([H])([H])SSC1([H])[H])C([H])([H])[H])C([H])([H])[C@]([H])(O[H])C2([H])[H]
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(C([H])=NC([H])=C1C#N)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=NC(=NN2C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]C1=C([H])N(C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C(C(=O)OC([H])([H])[H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=NN(N=N1)C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=NOC([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C(=O)N(C([H])([H])C1=C([H])OC([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])[H])N([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C([H])C(OC([H])([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])=C2[H])C([H])=C1[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])SC1=NC([H])=C(C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F
[H]O[C@@]([H])(C([H])([H])OC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]OC(=O)C([H])([H])[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(N([H])C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NN(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C2C(=C1[H])[C@@]13C([H])([H])C([H])([H])N(C([H])([H])C4([H])C([H])([H])C4([H])[H])[C@@]([H])(C2([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(S[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=NC(Cl)=C1[H])C1=C([H])C([H])=C2N=C([H])C([H])=C([H])C2=C1[H]
OC(=O)C1(CCN(CC1)C1=NC=C(S1)C(O)(C(F)(F)F)C(F)(F)F)C1=CC=CC=C1
[H]N(C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])N2C(=O)N(N=C12)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])C(=O)N([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])\N=C(\S[H])N([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])[H])[C@@]([H])(N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(C1=C([H])C(N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=NC([H])=C2Cl)C([H])=C1[H]
[H]N([H])C1=NC(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])[H])C([H])=C2[H])=C([H])C(=N1)N([H])C([H])([H])[H]
[H]N1C(=O)C([H])=C(C2=C1C([H])=C([H])C(=C2[H])N(C([H])([H])C(F)(F)F)C([H])([H])C(F)(F)F)C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])N1C(SC([H])([H])C2=C([H])C(F)=C([H])C(F)=C2[H])=NN=C1C1=C([H])C([H])=C([H])C([H])=N1
[H]N1C([H])([H])C(=O)N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])[C@@]([H])(C([H])([H])OC([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C1([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])N([H])C3=C2C(F)=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N([H])C([H])([H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])[N@]2C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C2([H])[H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])S[H])[C@]([H])(C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N(C(=O)C1=C(Br)C([H])=C([H])S1)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(C(=O)O[H])C([H])([H])[P@](=O)(O[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@@]12C([H])([H])[C@@]3(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]4=C(\C([H])=C(/[H])C5=C(OC6=C([H])C([H])=C(C([H])=C6[H])S([O-])(=O)=O)\C(=C(/[H])\C(\[H])=C6\N([H])C7=C(C([H])=C([H])C([H])=C7[H])C6(C([H])([H])[H])C([H])([H])[H])\C([H])([H])C([H])([H])C5([H])[H])C(C5=C4C([H])=C([H])C([H])=C5[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@](C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])[P@@](=O)(O[H])C([H])([H])[C@@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([O-])=O)(C1([H])[H])C([H])([H])[C@](C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])[P@@](=O)(O[H])C([H])([H])[C@@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C(=O)O[H])(C3([H])[H])C2([H])[H])C(=O)O[H]
[H]N1N=C(C([H])=C([H])C1=O)C1=C([H])C([H])=C(OC([H])(F)F)C(OC([H])([H])[H])=C1[H]
[H]N([C@@]1([H])C(=O)N(C2=C(F)C([H])=C(C([H])=C2[H])N2C([H])=NC(=C2[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C(\[H])=C(\C1=C([H])C([H])=C(Cl)S1)C([H])([H])[H]
[H]SC1=NC(=NN1C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(N=C(C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])C([H])([H])C3([H])[H])=C2C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1N=C(N(C1=S)C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1(N([H])C(=O)[C@@]([H])(S[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N=C(C([H])=C1[H])C1=C([H])C([H])=C([H])O1
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[H]C1=C([H])N2C(=C1[H])C(OC(=O)C([H])([H])C([H])([H])[H])=C(SC1=C([H])C([H])=C([H])C([H])=C21)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C1=NC2=C(C#N)C([H])=NN2C(=N1)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C2=C(C3=C(S2)N=C(OC3=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C(C2=C([H])C(=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C3OC([H])([H])C([H])([H])C3=C12
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[H]C1=C([H])C(=C2C(=C1[H])N(C1=C2C([H])=C([H])C2=C1C(=O)C([H])=C([H])C2=O)C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F
[H]N(C1=NC2=C([H])C([H])=C(C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1(C2=C([H])C([H])=C([H])O2)C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(C2=C(O1)C([H])=C([H])C([H])=C2[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]O[C@]([H])(C(\[H])=C(/[H])C(=C(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NN=NN1C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
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[H]N1C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C2=C1C(=NC([H])=N2)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(Cl)=C([H])N(C1=O)C([H])(C([H])([H])OC([H])([H])[H])C([H])([H])OC([H])([H])[H])C1=C(Cl)C([H])=C(OC([H])([H])[H])C([H])=C1Cl
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C(O2)C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]S\C(=N/N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(C2=NN=C3C([H])=C([H])C(SC4=C([H])C([H])=C(F)C([H])=C4F)=C([H])N23)C(=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C1(C([H])([H])[H])C([H])([H])OC1([H])[H])C1=C([H])C([H])=C([H])C2=C1OC(=C([H])C2=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(N(N=C1OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C([H])=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C1[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C(Cl)=C(F)C([H])=C1[H])C1=NN=C(O1)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C([H])([H])[H])C([H])([H])[C@@]([H])(C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(F)C([H])=C([H])C(F)=C1Cl
[H]C1=C([H])C(=C([H])C([H])=C1N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C2N=C(C([H])=C(N2N=C1SC([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(\C([H])=C(/[H])S(=O)(=O)OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])N([H])C1=C([H])C(F)=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C1=NC(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])=C(C#N)C([H])=N1)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C2=NC([H])=C([H])C([H])=C2C([H])=C1C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C(SSC1(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N2C(=C1[H])C(OC(=O)C([H])([H])[H])=C(SC1=C2C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])[C@@]([H])(N(C([H])([H])[C@@]1([H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(=NC2=C1C([H])=C(C([H])=C2Cl)C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])S[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N(C1=C2C([H])=C(SC2=NC([H])=N1)C1=C([H])C([H])=C([H])N1[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C(Cl)=C1[H]
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[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C(OS(=O)(=O)N([H])[H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@@]1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])[S@](=O)C([H])([H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C(C([H])=C1[H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C(=O)N(C([H])=C1[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@@]([H])(C(\[H])=C(/[H])C2=C(C([H])=C(Cl)C([H])=C2C([H])([H])[H])C2=C([H])C(=C(F)C([H])=C2[H])C([H])([H])[H])C1([H])[H]
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[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@]1([H])C2=C([H])C([H])=C(N=C2OC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C(F)=C1[H])C1=NN=C([H])S1
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=O)C2=C(O1)C(N([H])C(=O)C1=C([H])C3=C(C([H])=C([H])C(OC([H])([H])C4=NC5=C([H])C([H])=C([H])C([H])=C5C([H])=C4[H])=C3[H])C([H])=C1[H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C(Br)=C1OC([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@@]([H])(O[C@@]2([H])C([H])([H])N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])[C@@]([H])(OC([H])([H])C1=C(N=C(C#N)C([H])=C1[H])C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N1C([H])=C2N=C3C([H])=C([H])C([H])=C([H])C3=C2C([H])=C1C(=O)OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C([H])C([H])=C1C1=NC2=C([H])C([H])=C(N=C2N1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C2C([H])=NC([H])=C([H])C2=C1[H]
[H]C1=C([H])N2C(=NN=C2C2=C([H])C([H])=C3C([H])=C([H])C([H])=C(OC([H])([H])C4(F)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])F)C([H])([H])C4([H])[H])C3=N2)C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C(=O)C1=C([H])C([H])=C(C(=C1[H])C(F)(F)F)C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=O)N2C(=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])[C@@]([H])(C2([H])[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(OC1=C([H])C([H])=C(Cl)C(=C1[H])C([H])([H])N1C2=NC(F)=C([H])C([H])=C2C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C([H])([H])[H])C([H])([H])[H]