[H]N(C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C(N2C([H])([H])C([H])([H])N(C(=O)[C@]3([H])C([H])([H])N(C([H])([H])[C@@]3([H])C3=C([H])C([H])=C(F)C(Cl)=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(F)=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(O1)C([H])=C1OC(=O)C([H])=C([H])C1=C2OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(OC(=O)C3=C([H])C([H])=NC([H])=C23)C([H])([H])C1([H])[H])C1=NN(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C(C(=O)N([H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C([H])C(=O)N2C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])N(C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F)C([H])([H])C(F)(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C(=O)C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3C([H])([H])SC2=C([H])C([H])=C(Cl)C([H])=C2Cl)[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)C1(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])N=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])N2C3=C(OC([H])([H])[C@]2([H])C([H])([H])[H])C(N([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)=C(F)C(N([H])[H])=C3C1=O
[H]N(C(=O)[C@@]1([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C2=C(C([H])=C1Cl)C(=O)N([H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C(OC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]OC1=C([H])C(C2=C([H])C(=C3N=C(N=NC3=C2[H])N([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=NN=C(N2C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H]
[H]OC([H])([H])[C@]1(OC(=O)\C(=C(\[H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C1([H])[H])C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C3=C([H])C(=NN3C3=C([H])C([H])=C(C#N)C([H])=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=NC(=NC([H])=C2C([H])=C1C1=C(Br)C([H])=C([H])C([H])=C1Br)N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
CC(C)C1=C2N=C(C3=CC=CC=C3Cl)C3=C(NC2=NN1)C=CC(=C3)[N+]([O-])=O
[H]C1=C([H])C(=C([H])N1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C(=C([H])C(=C1[H])N1N=C([H])C([H])=C1[H])N1N=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(=O)N1C2=C(C([H])=C(C([H])=C2[H])C2=NOC(=N2)C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C([H])=C(Cl)C([H])=C(Cl)C2=N1)C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H])C([H])([H])[H])C([H])([H])C([H])=C(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C2N=C([H])C([H])=C([H])C2=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])[C@]([H])(N([H])C2=C([H])C([H])=C([H])C3=C([H])N=C([H])C([H])=C23)C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C1=C([H])C(=C([H])C(=N1)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])Cl)[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(Cl)N=C2N([H])N1C([H])([H])C([H])([H])C([H])(SC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
COC1=CC=C2C(SC3=C2N=CN=C3NC2=CC=C(Cl)C=C2Cl)=C1
[H]O[C@]([H])(C([H])([H])N(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)N1N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=NC3=C([H])C(=C([H])C([H])=C3N2C([H])([H])[H])C2(\C(=N/OC([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C3=NC([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)N(C([H])([H])C1=C([H])SC([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C(N=C(Cl)C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])C1=C([H])C(OC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C(C(OC([H])([H])C(=O)O[H])=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C(C(OC([H])([H])C(=O)O[H])=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(F)C(Cl)=C1[H])C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C12
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=NO[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C2=NC([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C1([H])[H]
[H]C1=C([H])C([H])=C(SC2=C(N=C3C([H])=C([H])C([H])=C([H])C3=C2Cl)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C(N=C(S1)C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
[H]OC(=O)C(\[H])=C(\C(\[H])=C(/[H])\C(\[H])=C(/C1=C([H])C(=C([H])C(=C1OC([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)C(F)(F)F)C([H])([H])[H])/C([H])([H])[H]
[H]N(C(=O)C([H])([H])SC1=NC(=C2C(=C1C#N)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C1=NN=C(S1)C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C(OS(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2Cl)=C([H])C(OC([H])([H])C2([H])C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])C([H])([H])C2([H])[H])=C1[H]
[H]N1C(=O)C([H])=C(C2=C([H])C([H])=C(F)C(F)=C12)C([H])([H])N(C1=C([H])N=C([H])C([H])=N1)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@]1([H])N=C(C2=NC([H])=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N(C1=O)C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]OC1=C([H])C(\C([H])=C(/[H])C([H])=O)=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])=C([H])[H])=C1O[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N([H])C([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])[C@]2([H])OC3=C(N=C([H])N=C3OC2([H])[H])N([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C#N)C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=N1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H])C(F)(F)F
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(=O)O[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
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[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(N1N=NC(=N1)C([H])([H])[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C(ON=C1C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])[C@@]2([H])S[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)(P(=O)(O[H])O[H])P(=O)(O[H])O[H]
[H]N(C(=O)C1=C([H])C(=C(Cl)C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]C1=NN(C2=C1C1(OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C2=C(N=C(N([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2C([H])([H])[H])C([H])=C1[H]
[H]N1N=C(C2=C([H])C3=C(N2[H])C([H])=C(C([H])=C3[H])C([H])([H])C(=O)C([H])([H])C([H])([H])[H])C2=NC([H])=C([H])C([H])=C12
[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C3=C2C([H])([H])C2=C3C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(=O)N([H])[H]
[H]C1=C([H])C([H])=C2N(C(=O)OC2=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C1=C(C([H])=NC(=N1)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C(=O)C([H])([H])[H])C([H])=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=N1
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(Cl)S1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C2=C(C1=O)C1=C(N3C4=C1C([H])=C([H])C([H])=C4C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C1=C2C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=NOC(=N1)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C([H])C([H])=C(C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3F)C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C([H])([H])SC1=NC2=C(C([H])=C3C(=N2)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(=O)N1C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)O[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(Cl)C([H])=C1F)(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@@]3([H])C([H])([H])[C@]1([H])C([H])([H])[C@](C3([H])[H])(C2([H])[H])S(=O)(=O)C([H])([H])[H]
CC1=C(Cl)C=CC=C1CN1C=NC(=O)C2=C1N=C(S2)N1CCOCC1
[H]N1C(SC([H])([H])C([H])([H])C([H])([H])SC2=NC([H])=C([H])N2C([H])([H])[H])=NC(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])[C@]([H])(C2=C(F)C([H])=C(F)C(F)=C2[H])[C@@]([H])(N([H])[H])C1([H])[H]
[H]N(C1=NC(=C([H])S1)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])[C@]2([H])C([H])([H])N(C(=O)C3=C([H])C(F)=C([H])C([H])=C3[H])C([H])([H])[C@]12[H]
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[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C(C#N)=C2[H])C11C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1OC([H])([H])[H]
[H]OC1=NC2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])=C1C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(O[H])C(O[H])=C1[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])[C@]21[H]
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[H]N(C1=C(Cl)C([H])=C([H])C(OC([H])([H])[H])=N1)C1=C2C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])C2=NC([H])=N1
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[H]OC1=C([H])C2=C(N([H])C(=C2[H])C(=O)C2=C([H])C3=C(N2[H])C([H])=C([H])C([H])=C3F)C([H])=C1[H]
[H]N([H])C1=N[C@](C(=O)N1C([H])([H])[H])(C1=C([H])N(N=C1[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1F
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[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C(F)C([H])=C1Cl
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[H]OC1=C([H])C([H])=C2C(=O)C([H])=C(OC2=C1[H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C(=C([H])C([H])=C1Cl)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])SC1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(=NC2=C([H])C([H])=C(Cl)C([H])=C12)N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C([H])C1=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C(=C(Cl)C([H])=C1[H])C([H])([H])[H]
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[H]N([H])C(=O)C1=C(SC(=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H])N([H])C(=O)C1=NOC(=C1[H])C([H])([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=NN=C(N2C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=C(F)C(F)=C(F)C(F)=C1F
[H]N([H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])N(C(=O)C11C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]OC1=C(C([H])=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)OC([H])([H])[H])C(=C23)C([H])([H])[H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
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[H]C1=C([H])C(SC2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)=C(C([H])=C1[H])C([H])([H])[H]
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[H]OC([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])[H]
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[H]N([C@@]1([H])C([H])([H])C([H])([H])[C@@](SC2=NC3=C([H])C(Cl)=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
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[H]O\N=C1/C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])=C([H])C([H])=C2C(=O)OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])=C(C(=O)N=C1SC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=N[C@@](N(C(=N1)N([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C(=O)N(C1=C(Cl)C(=C(Cl)C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])N2C(Br)=C(N=C12)C([H])([H])[H])C([H])([H])[H]
[H]C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=C1[H])C1=C(N(N=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2\C([H])=C(/[H])C(=O)N1N=C(C2=C1C([H])([H])[C@]1([H])[C@@]2([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=C([H])N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)OC([H])([H])[H]
NS(=O)(=O)C1=C(F)C(F)=C(SC2=S=NN3C4=C(C=CC=C4)N=C23)C(F)=C1F
[H]N([H])C1=C([H])C([H])=C([H])C2=C1C1=C(C([H])=C([H])C([H])=C1[H])C(=O)C2=O
[H]\C(C1=NC([H])=C([H])C([H])=C1[H])=C1\C([H])([H])N2[C@]3([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]1([H])C3([H])[H]
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[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2N=C1C1=C([H])[C@]([H])(N2C([H])([H])C([H])=C(C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O
[H]OC(=O)C1=C([H])C2=C([H])C(OC([H])([H])[H])=C([H])C(Cl)=C2O[C@@]1([H])C(F)(F)F
Cc1cnc(N)nc1-c1c[nH]c(c1)C(=O)N[C@H](CCO)c1ccccc1
[H]N(C(=O)C1=C(OC(=C1[H])C([H])([H])[H])C(F)(F)F)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=NC(=O)C([H])([H])N1C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C(C(=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)OC1=C([H])C([H])=C2N(C([H])([H])[H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3(C2=C1[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]ON(C([H])=O)C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(O[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C2=C13
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C2C(OC(=O)C([H])=C2C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(OC2=C(OC3=C([H])C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(P([O-])([O-])=O)S([O-])(=O)=O)C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=C([H])N(N=N1)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(N1C(=O)[C@@](C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C(=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C#CC2=C(OC([H])([H])[H])C([H])=C([H])C(=C2[H])C(=O)N2C([H])([H])C([H])([H])N(C3=NC([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=NC(C#N)=C([H])N1[H])C1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(N(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(S1)C1=NC(=NC([H])=C1[H])N([H])C([H])([H])[H])[C@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])([H])[C@]4(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C4([H])[H])C3([H])[H])C([H])([H])C2([H])[H])C2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1C2=C([H])C(=C(F)C([H])=C2C([H])([H])C1([H])[H])C(F)(F)F
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N(C2=C([H])C([H])=C(C([H])=C12)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C2C([H])=C(C([H])=C([H])C2=N1)C1=C(C([H])=C([H])N(C1=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])C1=C([H])C(O[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(N([H])C([H])([H])C(F)(F)F)(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1=O)C([H])([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C([H])C(=C([H])C([H])=C2N=C1C([H])([H])C([H])([H])[H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])C([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]3([H])C([H])([H])C1=C2C(OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(C#N)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])S(=O)(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CCCC(CCC)C(=O)N[C@H](COC1=C(OC)C=C(\C=C\C(=O)NO)C=C1)CC1=CNC2=C1C=CC=C2
[H]C1=C2C3=C(C([H])=C(N=C3N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])[H])N1C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=NSC(N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=C1C(=N[H])N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C2C(ON=C2C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C1[H]
[H]N1C(=O)C2=C(C1=O)C1=C(N3C4=C1C([H])=C([H])C([H])=C4C([H])([H])C([H])([H])C3([H])[H])C1=C2C2=C(N1[H])C([H])=C(C([H])=C2[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(\[H])C1=C([H])N(N=C1C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C(F)(F)F
[H]N1N=NN=C1C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]2([H])N1C2=C(N=C1C([H])(C([H])([H])[H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C([H])([H])C1(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[N@@+](C([H])([H])[H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C3=C(C([H])=C2[H])N2C([H])=C([H])N=C2C2=C(C([H])=C(O2)C2=C([H])C([H])=C(C#N)C([H])=C2[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC([H])([H])C([H])([H])[H])C2=C(O[H])C([H])=C(O[H])C([H])=C2C1=O
[H]N([H])C1=NC2=C([H])C(=C([H])C([H])=C2C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2F)C2=C([H])C(F)=C([H])C([H])=C2C1=O
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])N1C([H])=NC([H])=C1[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC1=C(F)C(=C([H])C([H])=C1[H])C1=C([H])N(C(=O)N(C1=O)C([H])([H])[C@]([H])(N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]OC(=O)C(C1=C([H])C(C2=C([H])C3=C(N([H])[H])N([H])C([H])=C([H])C3=N2)=C(O[H])C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]([H])(O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C2=C(N([H])C(=N2)C2=C([H])C([H])=C(Cl)S2)C([H])=C1[H])C1=C([H])C([H])=C(N2C([H])=C([H])C([H])=C([H])C2=O)C(F)=C1[H]
[H]N([H])C1=NC2=C(N=NN2C([H])([H])C2=C([H])C([H])=C(N([H])[H])C(=C2[H])C([H])([H])[H])C(=N1)C1=C([H])C([H])=C([H])O1
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1O[H]
[H]N1C(=O)N(C2=C([H])C([H])=C(F)C([H])=C12)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C(=O)N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])[C@@]([H])(C([H])([H])OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@]([H])(C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])N=C1C#N
[H]N(C1=NC2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2N2C1=NC([H])=C2C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=NC2=C(C([H])=C([H])C([H])=C2F)N1C1([H])C([H])([H])C([H])([H])N(C(=O)N([H])[C@]2([H])N=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C(C([H])=C([H])C([H])=C3[H])N(C2=O)C([H])([H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])\N=C(/[H])C1=C(N=C2SC([H])=C([H])N12)C1=C(Cl)C([H])=C(Cl)C(=C1[H])[N+]([O-])=O
[H]N(C1=NC(=C([H])C([H])=N1)N1C([H])=C([H])N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C(C2=C([H])C([H])=C(C([H])=C2N1C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)N(C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C(=O)C1=C(N(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C(OC([H])([H])C(=O)N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])N3C([H])=C([H])N=C23)C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@]([H])(C1=NC2=C(SC([H])=C2[H])C(=O)N1C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=NC(=C(O1)C1=C([H])N2C(=NN=C2N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C(N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3N=C2[H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(S1)C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C(=O)C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])C([H])(N([H])C(=O)C3=C([H])C([H])=C([H])N3[H])C([H])([H])C2([H])[H])C(=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])N1C(=O)C2=C([H])C(C#CC3=C([H])C([H])=C(C([H])=C3[H])C(=N[H])N([H])[H])=C([H])C([H])=C2N(C(=O)C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(OC([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(N([H])C([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])S(=O)(=O)C([H])([H])[H])C2=N1)C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]