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[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])SC2=C(C#N)[C@]([H])(C3=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])C(=O)N2C1([H])[H]
[H]ON(\C(S[H])=N\C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])\N=C(/[H])C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C([H])(N1C(N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])=C(C#N)C#N)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=NC([H])=C(Cl)N(C2=O)C([H])([H])C(=O)N([H])C([H])([H])C2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC(=O)N([H])C([H])([H])[C@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C([H])C(Cl)=C2[H]
[H]OC(=O)[C@@]([H])(OC1=C([H])C([H])=C(F)C(=C1[H])C([H])([H])N1C2=NC([H])=C([H])C([H])=C2C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(C([H])=NN2[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC(=O)C1=C(C([H])([H])OC(=O)C([H])([H])[H])C([H])([H])S(=O)(=O)[C@@]2([H])N1C(=O)[C@]2([H])OC([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C2C([H])=C(SC2=C([H])N=C1[H])C1=NN=NN1[H]
[H]C1=C([H])C(=C([H])S1)C1=C2N=C([H])C(=C([H])N2N=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])N(N=C1[H])C1=C([H])C(=C([H])C(=C1[H])N(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C([H])N=C([H])C(=C1[H])C([H])([H])[H]
[H]O[C@@]1([H])C(=O)O[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C3=C(N2[H])C([H])=C([H])C([H])=C3[H])C(=O)N([H])[C@@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CN1C=C(C=N1)C1=CC(F)=C(CN2C(=O)CCC3=C2C=CC=C3)C=C1
[H]N([H])C(=O)C1=C([H])N=C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C3([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C1=C([H])C2=C(N=C([H])N=C2O[H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(=O)O[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C(=O)N([H])C2=C([H])N(N=N2)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N([H])C(=O)C([H])([H])SC1=NN=C(N1N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(OC(=O)C([H])([H])[H])=C(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(Cl)=C(OC(=O)C([H])([H])[H])C2=C1[H]
[H]C1=NC(O[C@]2([H])C([H])([H])C3([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C(C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])=N1)C([H])([H])[H]
[H]OC(=O)[C@]12C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C5=C(N=C(N=C5[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
CC(C)C1=CC(=CS1)C1(CCCCC1)NC[C@@H](O)[C@H](CC1=CC(F)=CC(F)=C1)NC(C)=O
[H][C@@]12C[C@]3([H])C[C@@H](CC[C@@]3([H])[C@H](\C=C\C3=CC=C(C=N3)C3=CC(C)=CC=N3)[C@]1([H])[C@@H](C)OC2=O)NC(=O)OCC
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C2=C(C([H])=C(C#CC([H])([H])[H])C([H])=C2[H])C(=O)N([C@@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1=O
[H]C1=NC(OC2=C([H])C([H])=C(OC(=O)N3C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])=C([H])C([H])=C1C(F)(F)F
[H]N([H])C1=NC(C2=C([H])N([H])C3=C([H])C([H])=C(Br)C([H])=C23)=C(I)C([H])=N1
[H]C1=C(C(=O)OC([H])([H])C([H])([H])[H])C(=C2N1N=C([H])C(C#N)=C2OC1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H][C@@]12C[C@H](OC(=O)C3=CC=C(I)C=C3)[C@@]3(C)OC4=C([C@H](O)[C@]3([H])[C@@]1(C)CC[C@H](OC(C)=O)[C@@]2(C)COC(C)=O)C(=O)OC(=C4)C1=CN=CC=C1
[H]N1C(=O)N(C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2[H])C2(C1=O)C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C1=C([H])C([H])=C2N([H])N=C(C3=C([H])C4=C(N3[H])C([H])=C(C([H])=C4[H])C([H])([H])[H])C2=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N2N(C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@](N([H])[H])(C2=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]N1C(=O)N(C([H])([H])C1(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[N+]2(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C(=NC1=NC([H])=C([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)N([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])SSC([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C(=O)[C@@]([H])(N([H])C(=O)C2=C([H])C3=C(SC(Cl)=C3[H])N2[H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]OC(=O)C(OC1=C([H])C2=C(C([H])=C1[H])C(=NO2)C([H])([H])C([H])([H])C1=C(OC(=N1)C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@]([H])(O1)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H]
[H]O[C@]1([H])C2=C(N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C3=C(N=C2C([H])([H])C([H])([H])C1([H])[H])C([H])=C([H])C([H])=C3[H]
[H]S\C(=N/C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C2N([H])C([H])=C([H])C2=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2N=C(SC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C(C([H])=C([H])C([H])=C4[H])[N+]([O-])=O)C([H])([H])C3([H])[H])SC2=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C2C([H])=C([H])N([H])C2=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C3=C(S2)C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2C2=NN=C([H])N2[H])C2=C([H])N=C([H])C([H])=C12)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1Cl
[H]OC1=C([H])C2=C(C([H])=C1OC([H])([H])[H])C1=C3C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C2([H])[H]
[H]C1=C(N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])C1=C([H])C(=C(C#N)C#N)C([H])([H])C2([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C(Cl)C([H])=C2[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12F
[H]N(C1=C(N([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(=O)C1=O)C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]N([H])C1=NC2=C([H])N(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
O=C(CCCCC1CCSS1)OC1CCN(CC2CCCCC2)CC1
[H]N(C(=O)C1=NC([H])=C([H])N=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])C(Br)=C([H])C(=C1N(C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=NC2=C(C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=NN=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])C2=C([H])N=NC([H])=C2[H])C([H])=C1[H])C1=NC(=C([H])S1)C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]N(C1=C2C([H])=C(Cl)C([H])=C([H])C2=NN1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(OC([H])([H])[H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
[H]N1C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]N1C(=O)S[C@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C(OC2=C(C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N([H])[C@@]1([H])OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(N([H])C(=O)N([H])C([H])([H])C(=O)N([H])[H])=C([H])C([H])=C1[H])C([H])([H])O[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
CCN1C2=C(N(C)C(\C=C\C3=CC=C(Cl)C=C3)=C2)C(=O)N(CC)C1=O
[H]N(C(=O)C1=C([H])C(F)=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C(=O)N2C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])N3C([H])=C([H])C([H])=C3C2([H])[H])C(=C1[H])C([H])([H])[H]
O=C(NCC1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1)C1=CC=CN=C1
[H]N(C(=O)C([H])([H])C1=C([H])C(Br)=C(OC(=O)C([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]2([H])N(C([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C([H])C([H])=C([H])C([H])=C3Cl)[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(Cl)=C(N([H])C(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C2=O)C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C(\C([H])=C(/[H])C(=O)N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N([H])[C@]([H])(C(=O)N2[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]23[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C(C#N)=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C1=C2N=C(N1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])[H])C1([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(O1)C1=NC([H])([H])C([H])([H])N1[H]
[H]N(C(=O)C([H])([H])N1N=C(C([H])=C1C([H])([H])[H])C1=NC2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C1=NC(=C(S1)C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(C#CC2=C([H])N=C(N2C([H])([H])[H])C(=O)N([H])C([H])([H])[H])=C1[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])=NC(=C2Cl)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])[C@]2([H])O[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])N([H])C([H])([H])[H])[C@@]([H])(N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CCN1C(C)C2=C(C=CC=C2)C(SC2=NC3=CC=CC=C3O2)C1=O
[H]N=C(N([H])[H])N1C([H])([H])C2=C(C([H])=C([H])C(O[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C3=C([H])C([H])=C(OC4([H])C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C([H])=C3[H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC(=NC(=N1)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])[C@@]([H])(N2C([H])=C(C3=C([H])C([H])=C([H])C([H])=C23)S(=O)(=O)C2=C([H])C([H])=C([H])C(Cl)=C2[H])C1([H])[H]
[H]N1N=C(N(\N=C(/[H])C2=C([H])C(=C([H])C([H])=C2[H])[N+]([O-])=O)C1=S)C1=NN([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C(F)=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=C([H])C2=C1C([H])=C([H])C([H])=C2C([H])([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]S\C(=N/C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(C2=C([H])N=C3C([H])=C([H])C([H])=C([H])N23)=C(OC([H])([H])[H])C([H])=N1)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(C#N)C2=C(C(SC([H])([H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])=N1)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])SC2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C#N)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C(=O)OC([H])([H])C([H])([H])C#N)C1=C([H])C2=C(C([H])=C1[H])C(C#N)=C([H])N2C([H])([H])[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(C#N)(C([H])([H])[H])C([H])([H])[H])C(C#N)(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC1=C(F)C([H])=C([H])C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=NC(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2S[C@@]([H])(C([H])([H])[H])[C@]([H])(OC2=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1C(=O)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C2=C(C([H])=NN2[H])C([H])=C1[H]
[H]N(C(=O)N(N=O)C([H])([H])C([H])([H])Cl)C1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]2(C3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C2C3=C(C([H])=C(Cl)C([H])=C3N1[H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])C(=O)O[H])C([H])([H])N([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])N(C(=O)OC2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(OC([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])N(C([H])([H])C4=NC5=C6N4C([H])([H])C([H])([H])C([H])([H])C6=C([H])C([H])=C5[H])C([H])([H])[C@]23[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=S)SC2=C(C([H])=C(C([H])=C2[H])[N+]([O-])=O)[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2SC([H])=C(C2=N1)C([H])([H])[H]
[H]N(C1=C(C#N)C(=NN1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(\N=C(\[H])C1=C([H])C([H])=C([H])N=C1[H])C1=NC(=C([H])S1)C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])SC(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C(C#N)C([H])=C([H])C(N([H])C([H])([H])C(F)(F)C2=NC([H])=C([H])C([H])=C2[H])=[N+]1[O-])C([H])([H])C1=NC([H])=C([H])C([H])=C1N1N=C([H])N=C1[H]
[H]N(C(=O)[C@]([H])(N1N=NC(=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NOC(=N1)C1=C([H])C([H])=C([H])C([H])=C1F)C1=C([H])C2=C(C([H])=C1[H])N(C1=C2C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1Cl)C(=O)C(Cl)=C(O2)C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
CN1C=C(Cl)C(=N1)C(=O)NC1=CC=C(F)C(=C1)[C@@]1(C)N=C(N)OCC1(F)F
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C2C([H])=C([H])C(=NN12)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])OC2=C3OC([H])([H])C(C#N)=C([H])C3=C([H])C([H])=C2[H])C1([H])[H]
[H]N1N=C([H])C2=C1C(=C([H])C(=C2[H])C([H])([H])[C@]([H])(OC(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(C#N)=C([H])C([H])=N1)C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=N[H])N([H])[H]
CC[C@H](C)[C@@]1(C)N([C@@H](C(=O)N2CCOCC2)C2=COC(C)=N2)C(=O)[C@H](NC1=O)C1CC2=C(C1)C=CC=C2
[H]N([H])S(=O)(=O)[C@]([H])(Cl)S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC2=C(C([H])=C1OC1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N(C(=N2)C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(N(C1=O)C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C2=C(C([H])=C([H])C(OC([H])([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN([H])N=N1
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C([H])=C(Cl)C(=C2[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(S2)[C@]([H])(C2=C([H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C([H])C(=C2C([H])=C1[H])S(=O)(=O)C1=C2N=C(OC2=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(O[H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N2C(=S)S\C(=C(\[H])C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3[H])C2=O)C([H])=C1[H]
[H]N1N=C(\C([H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(C3=C([H])C([H])=NC([H])=C3[H])=C(C([H])=C12)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])N(N=C1C1=C([H])C([H])=C(C#CC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)[C@]1([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]\C(=N/N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N=C2C([H])=C(C([H])=C([H])N12)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1C([H])([H])[H]
[H]N([H])C([H])([H])C1=C(N=C(C(=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])[C@@]([H])(C(=O)OC([H])([H])[H])C1([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])[C@@]([H])(N([H])C(=O)C4=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C4[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@]([H])(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)O\N=C(\[C@]([H])(C([H])([H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)[C@]([H])(C1=C([H])C([H])=C2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2=C1[H])C([H])([H])[H]