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[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])S1)C1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1([H])[H])C1=C3C([H])([H])C([H])([H])C2=NN(C([H])=C12)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)N1C([H])([H])C([H])([H])N2C(=O)N(C(=O)[C@@]2([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C1=C([H])N=C2C(=C1[H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C(Cl)=C1[H])C2=C1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C(O1)C(=O)N(C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])N([H])[H]
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[H]N([H])S(=O)(=O)C1=C([H])C2=C(SC(=C2[H])C([H])([H])N([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])[H])S1
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[H]OC(=O)C1=C([H])SC([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
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[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1([H])N([H])C(=S)N([H])C2=C([H])C([H])=C([H])C(F)=C12
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[H]N(C1=C2C([H])=C([H])C(Cl)=C([H])C2=NC2=C1[C@]1([H])C([H])([H])C(=C([H])[C@]([H])(C2([H])[H])C1([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N=[N+]=[N-]
[H]N(C1=NC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C2=C(N([H])C(=N2)C2=C([H])C([H])=C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(C(=O)N([H])C2=C([H])C([H])=C(N([H])C3=NC(=C([H])C([H])=N3)C3=C([H])C([H])=C([H])N=C3[H])C([H])=C2[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C(N([H])C3=C2C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(\[H])=C2/C(=O)N([H])C3=C([H])C([H])=C(C([H])=C23)S(=O)(=O)N([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])[N+]([O-])=C1[H])C1=C([H])C([H])=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])N([H])C1=C([H])C(F)=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
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[H]C1=C([H])C(=NC(=C1[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C(Cl)C([H])=C(F)C([H])=C1[H])C([O-])=O
[H]N1C([H])=NC2=C1C([H])=C(C([H])=C2Cl)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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CC(C)C[C@H](CO)NC1=NC(SCC2=CC=C(C=C2)C#N)=NC2=C1SC(N)=N2
[H]C1=C(N(C(Br)=N1)C1=C([H])C(F)=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(C#C[C@@]2(N([H])C(=O)N([H])C2=O)C([H])([H])N2C(=O)C3=C(C([H])=C([H])C(OC([H])([H])[H])=C3[H])C2([H])[H])=C1[H]
[H]N(C(=O)OC1=C([H])C([H])=C2N(C([H])([H])[H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3(C2=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C2=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N(C1=C2C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C(=O)N=C(C([H])=C1N(C([H])([H])[H])C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C(=O)N([H])C1=NN=C(S1)S(=O)(=O)N([H])[H]
[H]N1C(=O)C([H])([H])N(C([H])([H])C([H])([H])C(=O)C2=C([H])C(Cl)=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C(S2)C(C(=O)N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]O[C@@]([H])(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])N=C([H])N=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C1C2=C(N(C3=C1C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]O\N=C1/C(=O)N(C2=C([H])C([H])=C([H])C(=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C2OC([H])([H])OC([H])([H])C2=C([H])C(F)=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C(OC2=NC([H])=NN3C([H])=C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C4([H])[H])C(=C23)C([H])([H])[H])C(F)=C1[H]
[H]N([H])C1=NC(=C(S1)S(=O)(=O)N1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=NSC(N([H])C2=C([H])C([H])=C(OC3=C([H])C(Cl)=C([H])C([H])=C3Cl)C([H])=C2[H])=C1\C(=N\[C@@]([H])(C([H])([H])O[H])C([H])([H])C([H])([H])[H])N([H])[H]
[H]N([H])C1=NC2=C(N=C([H])N2C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C(=N1)C1=C([H])C([H])=C([H])O1
[H]N(C(=O)C1=NC([H])=C([H])C(OC2=C([H])C3=C(OC(=N3)N([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C([H])=C([H])C2=NC([H])=NC2=C1[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])[C@]2([H])C3=C([H])C([H])=C([H])C(=O)N3C([H])([H])[C@]([H])(C1([H])[H])C2([H])[H]
[H]N([H])C([H])([H])C1=C([H])SC([H])=C1N(C([H])([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H])[C@]1([H])C2=NC([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(OC3=C(F)C(F)=C([H])C([H])=C3[H])N(C3=C([H])C([H])=C([H])N=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC(F)(F)F)C(Cl)=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=[N+]([O-])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C(=O)OC2=C([H])C(OC([H])([H])C3=C([H])C(=C([H])C([H])=C3[H])[N+]([O-])=O)=C([H])C([H])=C12
[H]OC1=C(O[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C2=C13
[H]C#CC([H])([H])OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])C(=O)C([H])([H])C([H])([H])[C@@]4(N([H])C(=O)C(\[H])=C(/[H])C5=C([H])C([H])=C(Cl)C([H])=C5[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]N(C(=O)C([H])([H])OC1=C2C(SC3=C([H])C4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])=C([H])N([H])C2=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C1=C2N=C([H])N(C2=NC([H])=N1)[C@]1([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]1([H])O[H]
[H]OC1=C(F)C([H])=C2C(=C1[H])C([H])([H])[C@@]([H])(N([H])C([H])([H])[H])[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC(C2=C([H])C([H])=C([H])O2)=C(S1)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])N(C1=C(C([H])=C([H])C([H])=C1[H])C([H])=C2[H])C([H])([H])C1=NC2=C(N=C(N=C2N=C1[H])N([H])[H])N([H])[H]
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[H]N(C(=O)N([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
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[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=NC(=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C(OC(=O)C([H])([H])[H])=C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)C(C2=NN(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C(C1=O)C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]3([H])N([H])C(=O)C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)O[H])C([H])([H])S[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])O[H])C([H])([H])S[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C2=C(N(C(=N2)N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N(C(=O)C([H])([H])N(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C2C([H])=C(N([H])C2=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])[C@]([H])(O[H])C([H])([H])[C@]4([H])C([H])([H])[C@@]([H])(OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])OC5=C([H])C([H])=C([H])C(OC6=C([H])C([H])=C(C([H])=C6[H])C([H])([H])N(C6=C([H])C([H])=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C6C([H])([H])[H])C([H])([H])C6=C([H])C([H])=C([H])C([H])=C6[H])=C5[H])C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])[C@]([H])(O[H])[C@]12C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C2=C(SC(=C2[H])S(=O)(=O)N([H])[H])S(=O)(=O)C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])OC([H])([H])[H])C(=O)C1=NOC(=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1OC([H])(F)F)N1C(=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])N1C(=NC(=C1C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(F)(F)F
[H]\C(=C(\[H])[C@@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C([H])=C1N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C(=C1C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)N3C(=C(C2=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C2C([H])=C(N=C12)C1=NC(=NO1)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C(C(=O)OC([H])([H])C([H])([H])[H])C2=C(S1)C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C2([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(=N/OC([H])([H])C([H])([H])C([H])([H])[H])\C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(Cl)C([H])=C(C([H])=C1[H])C(=O)N([H])N([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C1=NC([H])=C2C(=C1[H])N(N=C2C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])N([H])C2=C([H])C([H])=C([H])C(OC([H])([H])C(=O)N([H])S(=O)(=O)C3=C([H])C(Cl)=C(Cl)S3)=C12
[H]OC(=O)C([H])([H])C([H])([H])[C@]12C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]O[C@@](C1=C([H])N([H])C([H])=N1)(C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C(=O)N([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
CC1=CC=C(C=C1C(=O)NCC1=NC=NC=C1)N1N=C(C=C1NC(=O)NC1=C2C=CC=CC2=CC=C1)C(C)(C)C
[H]OC(=O)C(\[H])=C(\C(\[H])=C(/[H])\C(\[H])=C(/C1=C([H])C(=C([H])C(=C1OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])/C([H])([H])[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]OC(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N(C1=NC([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C1=C([H])C2=C(OC(=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])[H])C([H])=C1[H]
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[H]N([H])C(=O)C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])O[C@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N(C([H])([H])C([H])([H])OC([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Br
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(N=C3N(N(C(=O)C3=C2C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C21
[H]ON([H])C(=O)[C@@]1(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C([H])([H])C#CC([H])([H])[H])C([H])=C2[H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1Br)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
CC(C)S(=O)(=O)N1CCN([C@@H](CC2CCCCC2)C(=O)NC2=NC=CS2)C(=O)C1
[H]N(C(=O)C1=C(N=C(S1)\N=C(/[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C3C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C3=NC([H])=N2)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
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[H]N=C1S\C(=C(\[H])C2=C([H])C([H])=C([H])O2)C(=O)N1C1=NC([H])=C([H])S1
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[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C2=C(C([H])=C(I)C([H])=C2[H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]C1=NC2=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C(Cl)=C1[H])[C@]2([H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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CC1=C(C=C2C(=C1)C(C)(C)CCC2(C)C)N1C=CC2=C1C=CC(=C2)C(O)=O
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[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])O[C@@]([H])(C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@@]1([H])O[H]
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[H]C([H])([H])OC(=O)[C@@]1([H])OC(=O)[C@]2([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])[H])C(=O)[C@]3([H])[C@@]2(C([H])([H])[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1N(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=NC([H])=C(S1)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]O[C@]1([H])C([H])([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])O[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]ON(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C(C2=C([H])C3=C([H])N=C([H])C([H])=C3N2[H])=C1O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])[C@@]([H])(C(=O)N([H])[C@]([H])(C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(O[H])C([H])([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC2=C(N=C([H])N2C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(=O)C(C2=C([H])N(C3=C2N=C([H])C([H])=C3[H])C([H])([H])[H])=C(C1=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
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COC1=CC(C)=C(C(C)=C1)S(=O)(=O)N(C)CCOCC(=O)N1CCN(CCCN(C)C)CC1
[H]OC1(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
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[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(N(C3=C([H])C([H])=C(OC([H])([H])[H])N=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(C(F)=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N1N(C2([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(N2[H])C2=C(C3=C(C([H])=C(O[H])C([H])=C3[H])N2O[C@]2([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]2([H])O[H])C2=C1C(=O)N(N([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1C([H])([H])O[H])C2=O
[H]O[C@@]12C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]11C3=C(C([H])=C([H])C(OC(=O)C([H])([H])C4=C([H])C([H])=C(C([H])=C4[H])C4=C([H])C([H])=C([H])C([H])=C4[H])=C3[H])C([H])([H])[C@@]2([H])N(C([H])([H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C([H])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])=C1F
[H]N(\N=C(/[H])C1=C([H])C([H])=C(S1)[N+]([O-])=O)C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])S(=O)(=O)C([H])([H])C([H])([H])OC([H])([H])OC([H])([H])[H])C([H])([H])C1=C([H])SC([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(N([H])S(=O)(=O)C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])=C(OC2=C([H])C([H])=C(C([H])=C2OC([H])([H])[H])C([H])([H])C(=O)N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
CC(=O)N[C@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)B(O)O
[H]C([H])=C([H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C2C([H])=C(\C([H])=C(/[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])=C([H])C2=NC([H])=C1C#N
[H]N(C1=C([H])C2=C(N([H])C([H])=C2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[N+]([H])([H])[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C(=C2[H])C(F)(F)F)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N1[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
CN1C(N)=NC2(CC(C)(C)OC3=C2C=C(C=C3)C2=CC(=CC=C2)C(F)(F)F)C1=O
Cc1nc(NCC=C)sc1-c1ccnc(Nc2cccc(c2)[N+]([O-])=O)n1
[H]N([H])C(=O)C1=C2N([H])C3=C(C([H])=C(F)C([H])=C3[H])C2=C(N=C1[H])N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C(Cl)C([H])=NC(=N1)N([H])C1=C(OC([H])([H])[H])C2=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(O[H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC1=C(C(=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=C(C2=C(N=C([H])N=C12)N([H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=NC(=NC(=C1[H])C([H])([H])[H])N(C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1Br)C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]3([H])C(=O)C4=C([H])C([H])=C([H])C([H])=C4C(C3=O)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])[C@]4([H])C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C(\C([H])=C(/[H])C2=C([H])N=C([H])C([H])=C2[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[C@]([H])(OC1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)[C@@]1([H])N(C(=O)N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=O)[C@]1([H])C([H])([H])[C@]1([H])C([H])([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])\N=C(/[H])C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C3=C([H])C([H])=NC([H])=C3C([H])=C2[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C2=C([H])C([H])=C(Br)C([H])=C2C1=O
[H]N1N=C(C2=NC3=C(N2[H])C([H])=C([H])C([H])=C3C([H])([H])OC([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(=C([H])N=C12)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])N=C1[H]
[H]C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(OC3=C2[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]11N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C1=C(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C(=O)C([H])([H])F
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(O1)C(=O)OC([H])([H])[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C(N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2(C3=C(C([H])=C([H])C([H])=C3F)C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
Cc1cnc(Nc2ccccc2)nc1-c1c[nH]c(c1)C(=O)NCc1ccc(F)c(Cl)c1
[H]N(C([H])([H])C1=C([H])C([H])=NN1[H])[C@@]1([H])C(=O)N2C([H])([H])[C@]([H])(O[C@@]([H])(C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C(F)C([H])=C3[H])[C@]2([H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C(N([H])C(=C1C([H])([H])[H])[N+]([O-])=O)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[C@]1([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]ON([H])C(=O)[C@](C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
CN1C(C)=C(C(=O)N(C)C1=O)C1=CC=C(C[C@H](NC(=O)C2=C(Cl)C=CC=C2C)C(O)=O)C=C1
[H]N(C(=O)C1=C(C2=C([H])C([H])=C([H])C([H])=C2O1)C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])N1N=NN=C1[H])C([H])([H])[H]
[H]C1=NN(C([H])=N1)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(ON=C1C([H])([H])N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@@]1([H])[C@@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C1=C(N=C(C(OC([H])([H])[H])=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(\C([H])=C(/[H])C3=C([H])C([H])=NC([H])=C3[H])=C([H])C([H])=C12
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[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]N1C(=O)C([H])([H])OC2=C1C([H])=C(C([H])=C2Cl)C1=C([H])C(=NN1C1=C([H])C([H])=C(F)C([H])=C1C([H])([H])[H])C(F)(F)F
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[H]N1C(=O)N([H])[C@]2(N(C(=O)N([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])[H])C1=O
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[H]OC(=O)C([H])([H])C([H])([H])N([H])C([H])([H])C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1Cl
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[H]C1=C([H])C(=C([H])C([H])=C1C1=NC(=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C#N)C(F)(F)F
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[H]N(C(=O)OC1=C([H])C([H])=C2N(C([H])=O)[C@@]3([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3(C2=C1[H])C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C(=O)C1=C2N([H])C3=C(C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C([H])([H])N2N=C1C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1S2)C([H])([H])[H]
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NC(=N)NCCCC1=CN(CC(=O)N[C@H](C(O)=O)C2=CC=CC=C2)N=N1
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[H]\C(C1=C([H])C([H])=C([H])C([H])=C1[H])=C1/C(=O)C2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
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[H]C([H])([H])N1[C@@]2([H])C([H])([H])[C@@]([H])(OC(=O)OC([H])([H])C(Cl)(Cl)Cl)[C@]1([H])C([H])([H])C([H])([H])C2([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H]
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[H]N([H])C(=O)[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@]([H])(N([H])C(=O)[C@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C(F)(F)C1([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
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[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(\C([H])=C(/[H])C2=C([H])C(OC([H])([H])[H])=NC([H])=C2[H])=C([H])N=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
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[H]OC1=C([H])C([H])=C2C(SC(=C2OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(S1)C1=NN=C(SC([H])([H])C([H])([H])OC2=C([H])C([H])=C(Cl)C([H])=C2[H])N1C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N([H])C([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C2([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C1=C2C([H])=C([H])C([H])=C1[H])=C1C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(C#CC([H])([H])OC2=NSN=C2[C@]2([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])=C([H])C(C#CC([H])([H])OC2=NSN=C2[C@]2([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])=C1[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(\[H])=C1/C(=O)N([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C12
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])[N@]2C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])OC([H])([H])C1=C([H])C(I)=C([H])C(=C1[H])C([H])([H])[H]
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[H]C1=C([H])C(=NN2N=C(C(=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])[H]
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[H]N1C(=O)N(C2=C1N=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=NN=C(O2)C2=C([H])C(Cl)=C([H])C(=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C2C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C2C(=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
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[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=S)N([H])[C@]2([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])SN=C1[H]
[H]N(N(C(=O)N([H])[C@@]([H])(C1=NC([H])=C(C([H])=C1F)C1=C([H])C(Cl)=C([H])C(F)=C1OC([H])([H])C([H])(F)F)C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)C(F)(F)F
[H]N1C(C#N)=C([H])C([H])=C1C1=C([H])C([H])=C2N([H])C(=O)C([H])([H])C2=C1[H]
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[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C(F)(F)F)C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
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[H][C@@]12C[C@]3([H])C[C@@H](CC[C@@]3([H])[C@H](\C=C\C3=CC=C(C=N3)C3=C(C=CC=C3)C#N)[C@]1([H])[C@@H](C)OC2=O)NC(=O)OCC
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[H]N([H])S(=O)(=O)C1=C([H])C(Cl)=C(N([H])C(=O)C([H])([H])[N+]2=C(C([H])=C(C([H])=C2C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(O1)C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=NC([H])=C2[H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C2C(OC([H])=C2C2=C(C(=O)N([H])C2=O)C2=C([H])N(C3=C(C([H])=C([H])C([H])=C23)C([H])([H])O[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)[C@]([H])(N1C(=O)C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C([H])C([H])=C1F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1=C2N=C([H])C(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])=C(N([H])C3=C([H])C([H])=C(F)C([H])=C3C([H])([H])[H])C2=C([H])C([H])=C1[H]
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(SC3=C(C([H])=C([H])C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
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[H]N(C(=O)OC1=C([H])C([H])=C2C(=C1[H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])[C@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C2=C(OC([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])\C2=C(\[H])C([H])([H])N2C([H])=NC3=C2C([H])=C(C(=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
CC(=O)N[C@@H]1C[C@@H]2CC[C@H](C1)N2CC1=COC2=CC(OC3=NC4=CC=CC=C4S3)=CC=C12
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[H]N(C(=O)C1=C(Cl)C([H])=C([H])C(N([H])C(=O)C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C1[H])C1=C([H])N=C([H])S1
[H]OC([H])([H])C([H])([H])N(C1=NC(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C(OC2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC2=NC([H])=C(Br)C([H])=N2)=N1)C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(OC2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1[H]
[H]OC(=O)C1=C(OC2=NC([H])=C([H])C([H])=C2N([H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=NOC(=N1)C1=C([H])C(OC([H])([H])C([H])([H])[H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
O=C(NCC1CCOCC1)C1=NC=CC=C1NC(=O)C1=C2C=CC=CC2=C(CN2C=CN=N2)C=C1
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[H]OC(=O)C(\[H])=C(\C(\[H])=C(/[H])C([H])([H])C1(C2=C([H])C3=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])/C([H])([H])[H]
[H]N(C1=NC(=NC(=N1)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C2=C([H])N=C([H])O2)C(OC([H])([H])[H])=C1[H]
[H]SC([H])([H])[C@]1(C(=O)N([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(=O)C(=C([H])N3C2=C(OC([H])([H])[C@]3([H])C([H])([H])[H])C(N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])=NC([H])=C2[H])=C1F)C1=NN=NN1[H]
[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])C=CC2=CC(=O)C=C[C@]12C
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[H]C([H])=C([H])C([H])([H])N1C([H])([H])[C@@]([H])(N(C([H])([H])[C@@]1([H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])([H])[C@@]11C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NN([H])N=N1
[H]C([H])=C([H])C([H])([H])N1N=C(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC(\C([H])=C(\[H])C2=C([H])C([H])=C([H])C([H])=C2\C([H])=N\N2C(=O)OC([H])([H])C2([H])[H])=C([H])C(=N1)C([H])([H])[H]
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[H]N=C(SC([H])([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]C([H])=C([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H])=C1OC([H])([H])[H]
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[H]N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)C1=C([H])C(O[H])=C([H])C(O[H])=C1[H]
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[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])=C([H])[H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N1C(=O)C([H])([H])S(=O)(=O)C2=C1C([H])=NC([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C1C(=O)N2[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=C(\F)C(=O)N([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H])\C([H])([H])[H]
[H]N(C(=O)[C@@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NC(=C1C1=C([H])C([H])=NC(F)=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
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[H]OC1=C([H])C2=C(C([H])=C1[H])C1(OC(=O)C3=C1C([H])=C([H])C(=C3[H])C(=O)N(C([H])([H])C([H])([H])OC1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C1=C(O2)C([H])=C(O[H])C([H])=C1[H]
[H]N([H])C1=N[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C(C(=O)N([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2N=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1(ON=C(C1([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)O[H]
[H]N(C(=O)C1=C(Cl)C(=C([H])S1)C([H])([H])OC([H])([H])[C@@]1([H])OC(OC1([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C2=C(OC(=O)C([H])=C2[H])C([H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C([H])([H])C([H])([H])C([H])([H])C3=C([H])N([H])C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3F)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])C([H])([H])[S@@](=O)C([H])([H])[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N1N=C([H])C(=C1C([H])([H])[H])C1=C([H])C(=NC2=C(OC([H])([H])C3=C(Cl)C([H])=NC([H])=C3Cl)C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=[N+](C([H])=C1[H])C([H])([H])[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
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[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
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[H]OC1=C([H])C([H])=C2N([H])C3=C(C([H])=C([H])C([H])=C3[H])C(=NC2=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@](C(=O)N([H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N([H])C2([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C(F)(F)C1([H])[H]
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[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=NS2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(S[C@@]([H])(C(=O)OC([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NN=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C2N(C(=O)C(F)(F)C2=C([H])C([H])=C1[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC([H])([H])[C@@](N([H])[H])(C([H])([H])OP(=O)(O[H])O[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(SC2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])=C1F
[H]N(C1=C([H])C([H])=C2N([H])C([H])=C([H])C2=C1C([H])([H])[H])C1=C(C#N)C([H])=NC(=C1\C([H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]O[C@]1([H])[C@]([H])(O[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])[C@@]2([H])C([H])([H])OC([H])([H])C2([H])[H])[C@@]1(O[H])C([H])([H])[H])C([H])([H])OC(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(N([H])C3=C(C4=C(N([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])[H])C(C#N)=C([H])N=C2S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])SC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C(O[H])C(OC([H])([H])[H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]([H])(N([H])[H])C2([H])[H]
FC(F)(F)C1=CC=C(NC2=NC=NC(NCCN3CCOCC3)=C2)C=C1
[H]N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C(SC(=C1[H])C([H])([H])[H])C(=S)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(C2=C3N(N=C2C2=C([H])C([H])=C([H])C(=N2)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])=C2C([H])=C([H])C([H])=C([H])C2=N1
[H]OC(=O)[C@@]1([H])[C@@]([H])(C2=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=N2)[C@]1([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N(OC([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N1C(=O)[C@@]([H])(N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NC([H])=C([H])S1
[H]OC(=O)C1=C([H])C([H])=C([H])C(=N1)C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)S(=O)(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])[C@@]1([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2[H])N2N=C([H])C3=C(SC(=C3[H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C2=O)C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(C([H])=C(S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C(=O)N([H])C([H])([H])C1([H])[H]
Cl.COC1=NSN=C1OCCOCCOCCOCCOC1=NSN=C1C1=CCCN(C)C1
[H]C1=C([H])C2=NC(=C([H])C([H])=C2C([H])=C1[H])C1=NOC(=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C#N)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[125I]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C2=C([H])C([H])=C([H])C(Br)=C2[H])C([H])([H])[H])C([H])=C1Cl
NC(=O)[C@@H]1CCCC2=C1NC1=CC=C(Cl)C=C21
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C2N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(OC([H])([H])C([H])([H])C([H])([H])O2)C([H])=C1[H])C1=NN=C(S1)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C2C([H])([H])C([H])([H])[C@@]3([H])C(=C([H])C([H])([H])[C@@]4(C(=O)C([H])([H])C([H])([H])[C@@]34[H])C([H])([H])[H])[C@@]2(C([H])([H])C([H])([H])SC#N)C([H])([H])C([H])([H])C1=O
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(Br)=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C(Br)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])[C@]([H])(OC(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C1=C([H])C([H])=C([H])C2=C1N=C(C([H])=C2[H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]\C(=C1/C2=C([H])C([H])=C([H])C(F)=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N1C(=NC2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)C([H])([H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NN(C2=C1C([H])([H])[C@]1(C(=C2[H])C([H])([H])C([H])([H])C([H])([H])[C@]11O[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=C([H])C(=NC2=C(Br)C([H])=NN12)C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
COC1=CC=C(F)C=C1C(=O)N1CCN(CC1)C1=NN=C(C=C1)C(=O)NCCC1CC1
[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
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[H]N(C(=O)C([H])([H])SC1=C(SC([H])=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
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[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C([H])([H])N1N=C([H])C(Cl)=C(Cl)C1=O
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[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCO
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CN1CCC(CC1)NC(=O)C1=C(NC2CCNCC2)N=C(NCC2=C(Cl)C=CC(Cl)=C2)N=C1
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OC1=C(SC2=CN=NN2)C=C(NS(=O)(=O)C2=CC=CS2)C2=CC=CC=C12
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])C([H])([H])C([H])([H])[H])N([H])C(=O)C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C([H])C([H])([H])C3=C([H])C(Cl)=C([H])C([H])=C3[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2[C@](C1=O)(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C#C\C([H])=C(/[H])C2=C(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N1C([H])([H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2C2=C(Cl)C([H])=NC(=N2)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])S(=O)(=O)C2=C([H])C([H])=C3C([H])=C([H])C([H])=C(Cl)C3=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C1=C(OC2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(OC([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])=NC([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(N(C1=S)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(C([H])=C1[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
[H]N(C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C(Br)N(C([H])=N1)C([H])([H])[H]
CCC1=NC(=NC(OC)=C1F)N1C[C@H]2C(=O)N(C)C(=N)N[C@]2(C1)C1=CC=CC=C1
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C2=C(C([H])=C3OC([H])([H])OC3=C2[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])Br)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
[H]N1C([H])=C([H])C(OC([H])([H])[H])=C1\C([H])=C1/C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])N1N=NN=C1C1=C(C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])[H]
[H]C([H])([H])C([H])([H])C([H])([H])N1C2=C(N(N=N2)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=O)N(C1=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1N=NN=C1C1=C([H])C2=C(C([H])=NC([H])=C2S1)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C([H])C([H])=C(C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NN([H])C([H])=C1C(=O)N1C([H])([H])[C@@]2([H])C([H])([H])N(C(=O)C([H])([H])N3C(=O)[C@@]([H])(N([H])S(=O)(=O)C4=C([H])C5=C([H])C([H])=C(Cl)C([H])=C5C([H])=C4[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]([H])(C1([H])[H])C2([H])[H]
[H]N(C1=NN=C(SC([H])([H])C2=NOC(=C2[H])C([H])([H])[H])N1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C1=NC2=C(N=NN2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C(=O)OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C(=C1[H])C1=NN(C(=O)N1C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])N([H])C(=O)C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C2N(C(=O)C(=O)C2=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OS(=O)(=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(O[H])=N2)C1([H])C([H])([H])C([H])([H])N(C(=O)N([H])[C@]2([H])N=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C(C([H])=C([H])C([H])=C3[H])N(C2=O)C([H])([H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C(=C([H])C(=N1)C([H])([H])[C@]1([H])C([H])([H])N([H])C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])N([H])C([H])([H])C(F)(F)C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N1C(=O)C2=C(C1=O)C1=C(C([H])=C([H])C3=C1N(C([H])=C3[H])C([H])([H])[H])C1=C2C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)C1=NN=C(O1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C(OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])OC1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1=C(C(=C([H])C([H])=C1[H])C1=NOC([H])=N1)C1([H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]1([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NC4=NC(=NN4C(=N3)N([H])[H])C3=C([H])C([H])=C([H])O3)C([H])([H])[C@]2([H])C([H])([H])C1([H])[H]
[H]O[C@]1(C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]O[C@](C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])=C([H])[C@]2([H])C([H])([H])C([H])([H])N(C(=O)[C@]12[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C(=C(Cl)C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C([H])=C1C1([H])C([H])([H])C([H])([H])N(C(=O)N2OC(=O)C(=C2C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N(\C(=N/C#N)N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(SC(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]C1=C([H])C(=O)N(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])=C([H])C1=O
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(OC2=C(F)C(=C(F)C(OC3=C([H])C([H])=C([H])C(=C3[H])N3C([H])=NC([H])=C3[H])=N2)C([H])([H])[H])=C1[H]
[H]N([C@]1([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C1=C(C([H])=C([H])C(F)=C1[H])C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])[H])[C@]1([H])C2=C([H])C([H])=C(C([H])=C2[C@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1Br
[H]OC1=C([H])C([H])=C2N=C(SC2=C1[H])N([H])C(=O)C1=C(F)C([H])=C([H])C(O[H])=C1F
[H]N([H])C([H])([H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])S(=O)(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC3=C(C([H])=C(OC([H])([H])[H])C([H])=C3[H])C(=O)N2C([H])([H])C2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(Cl)=C2[H]
[H]N1C2=NN(N=C2C(=NC2=C1C([H])=C([H])C(F)=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])C2=C(C3=C(C([H])=C(F)C([H])=C3N2C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C2C(=C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])N([H])C3=C([H])C(F)=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C2OC([H])([H])C3(C2=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NC(=C(N1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC1=C([H])C([H])=C2C(O[C@]([H])(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])[C@]([H])(C2=O)C([H])([H])[H])=C1[H]
[H]N(C1=NC([H])=NC2=C1N=NN2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(\C([H])=C2\C3=NC4=C([H])C(Cl)=C([H])C([H])=C4C(=O)N3C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])=C([H])C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2C([H])([H])[H])C([H])([H])[H]
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[H]C1=C2C3=C(C([H])=C([H])C([H])=C3N1C([H])([H])[H])C(=O)N(C([H])([H])C2([H])[H])[C@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C3N(N=C([H])N=C3N([H])C3=C([H])C4=C(C([H])=C3[H])N(N=C4[H])C([H])([H])C3=C([H])N=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=NC(C2=NC(=C([H])S2)C([H])([H])[H])=C(N1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])[C@]1([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C1([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)[C@@]1([H])[C@]2([H])C([H])([H])N(C3=C(C#N)C([H])=C([H])C([H])=N3)C([H])([H])[C@]12[H]
[H]ON([H])C(=O)C(C([H])([H])C([H])=C([H])[H])(C([H])([H])C([H])=C([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)C(Br)=C(OC([H])([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])S2(=O)=O)C([H])([H])C1([H])[H]
[H]C1=NN(C(=C1[H])C1=C([H])C(=NC2=C(OC([H])([H])C3=C(C([H])=NC([H])=C3Cl)C([H])([H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])N(N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1F)C([H])([H])[H]
[H]OS(=O)(=O)C([H])([H])C([H])([H])C([H])([H])N1C(=S)N(C(=O)C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C#N)C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])[C@@]([H])(OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])[C@@]1([H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])C2([H])[H])C1=C([H])C([H])=C(O[C@]2([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C1N([H])C(C([H])=C(C1=C2[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1SC1=C([H])C(F)=C(C(=C1[H])C1(OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])N(C(=O)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])N(C1=O)C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C3C(=NC2=C1[H])C([H])([H])N(C#N)C3([H])[H]
[H]N1N=C(C([H])=C1C(=O)N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])[C@@]4(C([H])([H])C3([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[C@]4([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C([H])([H])C(F)(F)F)(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])O[C@@]([H])(N2C([H])=C(C3=C2C([H])=C([H])C([H])=C3Cl)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@@]1([H])O[H]
[H]C([H])=C([H])C([H])([H])N1C(=O)N(C2=C(N(C(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])Cl)C1=O)C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])[C@@]1([H])ON=C(C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C1([H])[H])C([H])([H])[P@@](=O)(O[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC([H])=NC2=C1C([H])=C(O2)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=NC2=NC3=C([H])C([H])=C([H])C([H])=C3N=C12
[H]C1=NN2C(N=C(C([H])=C2N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2Cl)C([H])([H])OC([H])([H])[H])=C1[H]
[H]N1C([H])([H])C([H])([H])O[C@]([H])(C1([H])[H])[C@@]([H])(OC1=C(OC([H])([H])[H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]C([H])=C([H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C3=C(N=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(O[H])=C1C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)N(C(=O)C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(F)C([H])=C2C2=C1C([H])([H])[C@]1([H])N(C([H])([H])C3=C(I)C([H])=C([H])C([H])=C3[H])[C@@]2([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NN(C2=C1C(=C([H])C([H])=C2[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N(C(=O)ON=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[C@@]([H])(OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C#C[H])N([H])C(=O)C([H])([H])[C@]1([H])C(=O)N(C([H])([H])C([H])([H])C2=C([H])C(=NC([H])=C2[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(SC([H])=C2[H])C(=N1)C(=O)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=C(Br)C([H])=NC(=N1)N([H])[C@]([H])(C1=NC([H])=C(F)C([H])=N1)C([H])([H])[H]
[H]N([H])C1=C([H])C(C#CC2=C([H])C([H])=C([H])C(=C2[H])C(=O)N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=NC(OC([H])([H])[C@@]2([H])OC([H])([H])C([H])([H])C2([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C(=NC([H])=C1N(C(=O)C(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C2(OC3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(ON=C1OC([H])([H])C#CC([H])([H])[N+]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)N1C([H])([H])C([H])([H])C1([H])[H]
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[H]O\N=C(/[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC(=C([H])S1)[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C(C([H])=C([H])C([H])=N1)C(=O)C1=NC(=C([H])C([H])=C1Cl)N1C([H])([H])C([H])([H])N([H])[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
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[H]N(C1=NC([H])=C2N(C(=O)N(C2=N1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
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[H]N([H])C1=NC([H])=NC2=C1C(=C([H])N2C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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CC[C@@H](COC(=O)COCCOC)Nc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](COC(=O)COCCOC)c1cccc(Cl)c1
[H][C@@]12CCC(=C)[C@H](\C=C\C(C)=O)[C@@]1(C)CCCC2(C)C
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[H]OC(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])N1N=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C3C([H])=C(C([H])=C([H])C3=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])[N+]([O-])=O
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[H]N(C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(C#CC2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Br)=C([H])C(=C1[H])C([H])([H])SC1=NN=C(O1)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
CC(C)(C)C1=NN(C(NC(=O)NC2=C3C=CC=CC3=CC=C2)=C1)C1=CC=C(CCC(O)=O)C=C1
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[H]N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=N1)N1C([H])([H])C([H])([H])[C@]([H])(C2=C(F)C([H])=C(F)C(F)=C2[H])[C@@]([H])([N+]([H])([H])[H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(SC2=C([H])C([H])=C(Cl)C([H])=C2[H])=NN(C1=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])([C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])OC(=O)N(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])N1C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C(C([H])=C(O[H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(N([H])C3=C2C([H])=C([H])C([H])=C3[H])C1([H])[H]
[H]N(C1=NC([H])=C(S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]N1C(=O)C(C2=C([H])C(=NO2)C([H])(C([H])([H])[H])C([H])([H])[H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C12
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])N2C(=O)N=C([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C(N([H])C2=NC(=NC3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC1=NC([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N(C1=NC(N([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C2N=C([H])N(C2=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])O[H]
[H]OC([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C2=C([H])N([H])C3=C([H])C([H])=C(N([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C(F)=C(F)C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C(=S)C2=C1C(OC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2[C@@](OC([H])([H])C1=O)(C1=C([H])SC([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])C(F)=C([H])C(C#N)=C1[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H]
[H]C1=NC(=NC(C2=C([H])C([H])=C(Br)C([H])=C2C([H])([H])[H])=C1C([H])([H])[H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C1([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=NN2[C@@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C(C2=NC3=C(C([H])=C([H])C(Cl)=C3[H])N2C([H])([H])[H])=C1C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])[N@]2C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C#N
OC[C@H]1OC([C@H](O)[C@@H](O)[C@@H]1O)C1=CC(CC2=NN=C(S2)C2=CN=CC=C2)=CC=C1
[H]N(C(=O)[C@]1([H])C([H])([H])N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=NOC(=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C(C([H])=C3C([H])=NC(SC([H])([H])[H])=NC3=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([C@@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C3=C([H])C([H])=C(O3)C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C(Cl)C(=N1)N([H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@](O[H])(C([H])([H])[H])[C@]1([H])O[H]
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[H]N=C(OC([H])([H])[H])N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]2([H])N(C(=O)N([H])S(=O)(=O)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N(C2=C3C4=C(C([H])=C2[H])C(=NN4C([H])=C3C1([H])[H])C(F)(F)F)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])[C@]([H])(OC([H])([H])C1=C(C([H])=C(C#N)C(=O)N1C([H])([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(C#N)C(Cl)=C1[H]
[H]N(C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=O)C2(O1)C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C([H])=C([H])N=C12)C([H])([H])C1=NN=C2N=C([H])C(=NN12)C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC(C1=C([H])C(Cl)=C(C([H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(F)(F)F)(C(F)(F)F)C(F)(F)F
[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C([H])C([H])=C([H])N=C12)C([H])([H])C1=NC2=C(S1)C(F)=C([H])C(F)=C2[H]
[H]N(C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(C2=C([H])C([H])=C([H])C(Cl)=C2[H])=C2C([H])=C([H])C([H])=C([H])C2=N1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])[C@@]([H])(C1=NN=C(N1C([H])([H])C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C(N(C2=NC(=C([H])C(=N2)C([H])([H])[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H])C(Br)=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(C([H])([H])C(=O)OC([H])([H])[H])[C@@]2([H])N(C([H])([H])[H])[C@@]([H])(C1([H])[H])[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]N([H])C1=NC2=C(C([H])=N1)C([H])([H])N(C(=O)N2C([H])([H])[H])C1=C(C([H])=C([H])C(N([H])C(=O)C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])N=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@](C1=C([H])C2=C([H])C(Cl)=C(C([H])=C2N1[H])C(F)(F)F)(C([H])([H])[H])C([H])([H])OC(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C(=C(Cl)C([H])=C1[H])[N+]([O-])=O)C1=C(C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])([H])C2=C1C([H])([H])N(C(=O)N([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2(C([H])([H])[H])C([H])([H])[H])C1=NC(Cl)=NC(OC([H])([H])C([H])([H])C([H])([H])[H])=N1
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(\C([H])=C1/C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1I)[C@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])(OC([H])([H])[H])OC([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]O[C@@]1(C2=C([H])C([H])=C([H])C(C#N)=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(F)C([H])=C2F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]O[C@]1(OC(=O)C(=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C(C([H])=C([H])C(N([H])C2=NC([H])=C(O2)C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C1=C([H])N=C([H])O1
[H]N(C(=O)C1=NC([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C3=NC(Cl)=C([H])C(=C3C([H])=C2C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC(=O)C1=C([H])N(C2=C(C([H])=C(F)C(=N2)N2C([H])([H])[C@]([H])(N([H])[H])[C@]([H])(C3=C([H])C([H])=C(N([H])[H])C([H])=C3[H])C2([H])[H])C1=O)C1([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(SC([H])([H])C(=O)N2C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC1=NC(=C([H])C(=O)N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C(C([H])=C1[H])C1=C([H])N=C([H])O1
[H]OC1=C([H])C([H])=C2O[C@]3([H])C([H])([H])N(C([H])([H])[C@]([H])(O[H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])[C@@]3(C2=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C(O[H])C([H])=C2C3=C(C4=C(N3[H])C([H])=C(C([H])=C4[H])C3=C([H])C([H])=C(C([H])=C3[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C(=[N+]1C([H])([H])[H])C([H])([H])[H]
[H]N1N=C([H])C2=C1C(=C([H])C([H])=C2[H])C(=O)N1C([H])([H])C([H])([H])C2(OC3=C(C(OC([H])([H])[H])=C([H])C([H])=C3[H])C(=O)C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]1(C#CC2=C([H])C([H])=C(C([H])=C2C([H])([H])C([H])=C([H])[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=NC3=C(N=C(N=C3N=C2[H])N([H])[H])N([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]C1=C(N=C(N=C1C([H])([H])[H])N(C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1Br)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(N=C([H])C([H])=C2[H])N(C(=O)C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C2=NC(=O)C([H])([H])S2)[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C(F)(F)F
ClC1=CC=C(C=C1)C1=CC=C(NC(=O)CCCCN2CCCCC2)C=C1
[H]C1=C([H])C(=C([H])C([H])=C1I)[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])C([H])([H])F)[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(C(=NC(=N1)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])N([H])C([H])([H])C1=C([H])C([H])=C([H])O1)[N+]([O-])=O
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C(F)(F)F)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])[C@@]([H])(O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])C1=NN([H])N=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=NN(C(=C2C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1F
[H]C([H])=C1C2=C([H])C([H])=C([H])C([H])=C2C(=O)N(C2=C([H])C([H])=C(C([H])=C12)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N1C([H])([H])C2=C(C([H])=C([H])C(OC([H])([H])C3([H])C([H])([H])C([H])([H])N(C4=C(C([H])=NC([H])=C4[H])C(=O)OC([H])([H])[H])C([H])([H])C3([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1N=NN=C1C1=C([H])C([H])=C([H])C(=C1[H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=NC([H])=C([H])C2=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]O[C@@]1([H])C2=C(N([H])C([H])=NC1([H])[H])N(C([H])=N2)C([H])([H])C([H])([H])C1=C2C(=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC1(C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(C#N)(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C2C([H])=C([H])N([H])C(=O)C2=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C2=NN=C(C(=O)N2C2=C([H])C(Cl)=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]OC(=O)[C@]1([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[H])C2=C(C([H])=C(O[H])C([H])=C2[H])C1([H])[H]
[H]O[C@@]([H])([C@@]([H])(OC([H])([H])C(\[H])=C(/[H])C#C[H])C(=O)N([H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]1([H])O[H])[C@@]([H])(O[H])[C@@]([H])(OC([H])([H])C(\[H])=C(/[H])C#C[H])C(=O)N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])O[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(=C(\OC(=O)C([H])([H])[H])C(F)(F)C(F)(F)F)\C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C2C([H])=C(OC2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])O1)C(=O)OC([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=NC2=C(O[H])C([H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C([H])=C([H])N2N=C1[H])C(=O)OC([H])([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C([H])=C([H])C(=C2[H])N1C(=C(C2=C1C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2=O)C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OC(=O)[C@@]1([H])N(C(=O)[C@@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])C([H])([H])OC1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])N1C(=O)C2=C(ON=C2C2=C1C([H])=C([H])C([H])=C2Cl)C([H])([H])[H]
[H]N(C1=C(C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O)C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N1C([H])([H])[C@@]([H])(OC2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C2=C(N=C(N2C([H])([H])[H])C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(N([H])C(=O)C([H])([H])C1=NN=C2N1C([H])=C(N=C2C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N1C(SC([H])([H])C2=C([H])C([H])=C([H])C(C(=O)OC([H])([H])[H])=C2Br)=NC2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])[C@]([H])(C1=C(N2C([H])([H])C([H])([H])N(C(=O)[C@]3([H])C([H])([H])N(C(=O)C4([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[C@@]3([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C(F)=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(\C(S1)=N\C(=O)C([H])([H])Cl)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]O\C(=C(\C#N)C(=O)N([H])C1=C([H])C([H])=C(C2=C([H])C(F)=C(F)C(F)=C2[H])C(=C1[H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]\C(=C(/C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C3=C(C([H])=C4C([H])=C(OC([H])([H])[H])C([H])=C([H])C4=N3)C([H])([H])[C@@]12O[H]
[H]OC1=C([H])C([H])=C(C([H])=C1Cl)C(=O)C([H])([H])SC1=NC2=C([H])C(OC([H])([H])C3=C([H])C(=C([H])C([H])=C3[H])C(=O)OC([H])([H])[H])=C([H])C([H])=C2N1[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])C1=NN=C(S1)S(=O)(=O)N([H])[H]
[H]ON([H])C(=O)C([H])([H])C1=C([H])C([H])=C(S1)C1=C([H])SC(=N1)N([H])C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC(=NC(=N1)N([H])C([H])([H])[H])N([H])C([H])([H])[H]
[H]ON1C(=O)[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C(=C1C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N([H])C1=NC(=C(S1)C1=C([H])C2=NC([H])=C([H])N=C2C([H])=C1[H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)N(C([H])([H])C1(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N1N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2\C1=N/C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])S(=O)(=O)[C@]1([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C([H])C(=C([H])S1)C1=C([H])N=C([H])C(=C1[H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(F)=C(C([H])=C1[H])C1=C([H])N([H])C2=C([H])C([H])=C(C([H])=C12)C1=NC(OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])[H])=C([H])N=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=NC(N([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C2N=C([H])N(C2=N1)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=NC(N([H])C3=C([H])C(=C([H])C([H])=C3N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C3=C(C([H])=C(OC([H])([H])[H])C1=C3[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])=C(Cl)C([H])=N2
[H]N([H])C(=O)C1=C(N=C(N=C1[H])N([H])[C@]1([H])C([H])([H])C([H])([H])OC([H])([H])[C@]1([H])N([H])[H])N([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N([H])C1=C(C([H])=C([H])C(Cl)=C1[H])[C@]([H])(N1C(=O)C2=C([H])C(I)=C([H])C([H])=C2N(C(=O)[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC3=C(N2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C(=O)N(C2=C3C([H])=C([H])C(=C2[H])C([H])([H])OC([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C2=C([H])C([H])=NC(=N2)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2N(C([H])([H])C3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C([H])([H])C([H])([H])C2=C1[H]
[H]N(C1=NC(Cl)=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C2=NC([H])=C(C([H])=C12)C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])C([H])=C([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
Cl.COC1=CC=C2CCCC3(CCN(CC4=CC=CC=C4)CC3)C2=C1
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(N([H])C(=O)N1C(=O)[C@]([H])(C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])N([H])C(=O)C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C2C([H])=C([H])C([H])=C(N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])SC1=NC([H])=NC2=C1C([H])=NN2C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C1=C([H])C(=NC([H])=N1)N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])N([H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C(=O)N([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=NC(=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1([H])[H]
[H]O[C@]1([H])C([H])([H])C2=C([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])[C@]([H])([C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C(O[H])(C([H])([H])[H])C([H])([H])[H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C([H])C(=C([H])C1=O)C1=C([H])N=C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
CCN(C)C(=O)C1=CN=C2N(CCCOC)C(NC(=O)C3=CC=CC(=C3)C#N)=NC2=C1
[H]O[C@@]([H])(C([H])([H])N1C(=O)N(C2=C(C([H])=C(S2)C([H])([H])C([H])([H])[H])C1=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NOC(=O)N1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C(S2)C2=NC([H])=C(S2)C2=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C(=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])C2=C(C(=O)C3=C([H])C([H])=C(Cl)C([H])=C3[H])C3=C(C([H])=C(F)C([H])=C3N2C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[N+]([O-])=O)N2C(=O)N(N=C12)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC2=C(N=NN2C2=C1SC([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC1=C(C([H])=C([H])C([H])=C1N([H])C1=C(N([H])N(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])[H])C(=O)C1=O)C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(=O)N(C2=O)C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])([H])C([H])([H])N([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=NC(=C([H])C([H])=C2C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C3OC([H])([H])C(=O)N(C3=C([H])C([H])=C2[H])C([H])([H])C([H])(F)F)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])[C@@]([H])(C2([H])[H])[C@]1([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])[C@@]2([H])C3=C(C(OC([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N1C2=C([H])C(=NN2C2=C([H])C([H])=C([H])C([H])=C2C1=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)C([H])=C([H])C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C12)C1=C(C(Br)=C([H])S1)C1=NC([H])=NN1[H]
[H]C1=NC(Cl)=C(N=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)[C@@]3([H])[C@@]([H])(C2=O)[C@@]2([H])C([H])([H])C([H])([H])[C@]3([H])[C@@]3([H])C([H])([H])C([H])([H])[C@@]23[H])C([H])([H])C1([H])[H]
[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)[C@]3([H])[C@]([H])(C2=O)[C@]2(OC(=O)C([H])([H])[H])C([H])=C(C([H])([H])[H])[C@@]3([H])[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C([H])C(C3=C([H])C(=C([H])C([H])=C3OC([H])([H])C([H])([H])[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C(C([H])=C2C(=N1)N([H])[H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])N2C(=O)C3=C(ON=C3C3=C2C([H])=C([H])C([H])=C3Cl)C([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C2=C([H])C(Cl)=C(C#N)C([H])=C2[H])[C@@]([H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(N2C([H])([H])[H])C([H])([H])[C@]23C4=C(C([H])=C([H])C(OC([H])([H])[H])=C4[H])C([H])([H])[C@]2(C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])S(=O)(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)OC3=C2C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NOC2=C([H])C([H])=C([H])C(=C12)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(S2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC3=C([H])C([H])=NN3C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1=C([H])C([H])=C(C#CC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C([H])N=C1[H])C1=C([H])C([H])=C2N([H])N=C(C2=C1[H])C(F)(F)F)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C(N(C2=C([H])C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C12)C([H])([H])C#N)C(=O)N1C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)[C@]1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C2([H])[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@@]([H])(C(\[H])=C(/[H])C2=C(Cl)C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C1([H])[H]
[H]N(\N=C(/[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(OC([H])([H])[H])C(=O)C1=C(F)C([H])=C(F)C(N([H])C2=NC([H])=NN3C([H])=C(C4=NC(=NO4)C([H])([H])[H])C(=C23)C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(O[H])[C@]([H])(N([H])[H])C([H])([H])SC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C([H])=C(C([H])=C(C2=N1)C1=C([H])C([H])=C([H])C(OC([H])(F)F)=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C#N
[H]N(\C(=C1/C(=O)N([H])C2=C([H])C(=C([H])C([H])=C12)C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]([H])(C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[P@@](=O)(C([H])([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(SC2=C([H])C(C(=O)N3C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])=C(C([H])=C2[H])C([H])([H])[H])S1)C1=NC(Br)=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(Br)C([H])=C2[C@@]([H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])N=C1C(=O)N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C1=NS(=O)(=O)C2=C([H])C(F)=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])N([H])\N=C(/[H])C1=C(N2C3=C1C([H])=C([H])C([H])=C3C(=O)N([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C([H])([H])C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@@]12C([H])([H])C([H])([H])C(=O)[C@]3([H])OC4=C(OC([H])([H])[H])C([H])=C([H])C5=C4[C@]13C([H])([H])C([H])([H])N(C([H])([H])C1([H])C([H])([H])C1([H])[H])[C@]2([H])C5([H])[H]
[H]OC(=O)C1=C(C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C2O[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N1C(=C([H])C2=C([H])C(C3=C([H])N=C([H])O3)=C(OC([H])([H])[H])C([H])=C12)C1=C([H])SC2=C1C([H])=C([H])C([H])=C2[H]
[H]OC1=C([H])C([H])=C(N([H])C2=C([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])=C1[H]
[H]O[C@]1([H])[C@]([H])(O[C@@]([H])(N2C([H])=C([H])C(=O)N([H])C2=O)[C@]1([H])N([H])[H])C([H])([H])O[P@@](=O)(O[H])OP(=O)(O[H])O[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N1C(=O)C(N([H])C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])C([H])([H])[H])C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C(SC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC([H])=C2C(=O)N(C3=NC4=C(C([H])=C([H])C([H])=C4[H])N3C2=N1)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])[C@@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(S1)C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C([H])=NN(C2=C1C([H])([H])[H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])[H]
[H]OC1=NC(=O)N(C([H])=C1F)[C@@]1([H])OC([H])([H])C([H])=C([H])C1=O
[H]N(C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])O[C@@]2(C3=C1C([H])=C(C(Cl)=C3[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)[C@]1([H])C([H])([H])N(C([H])([H])[C@@]1([H])C1=C(F)C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
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[H]N(C(=O)N([H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC(=C([H])C([H])=C2C#N)C([H])([H])O[C@@]([H])(C2=C([H])N=C([H])N2C([H])([H])[H])C2=C([H])C(=C(C#N)C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(Br)C(OC(=O)C([H])([H])[H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C(=C([H])C(=C1[H])N1N=C(C#N)C(=O)N(C1=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])C([H])([H])[H])N2N=C([H])C(=C2[H])C(=O)N([H])C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
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[H]N(C(=O)N([H])C([H])([H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]SC1=NC(=NN1C([H])([H])C1=C([H])C([H])=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=NN(C([H])=N1)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@@]1([H])OC2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(=S)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=NC2=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(OC4=NC([H])=C(C([H])=C4[H])C(=O)N([H])[H])C([H])=C3[H])C([H])=C([H])C([H])=C2N1[H]
[H]C1=C([H])C(F)=C(C([H])=C1F)[C@]([H])([C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(OC([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C2([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=N\[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])\N([H])C(=O)C1=C(SC([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C(F)=C([H])C(F)=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(=C(Cl)C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]C#CC([H])([H])N(C(=O)[C@@]1([H])N([H])[C@@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C1([H])[H])C([H])([H])C#N
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(SC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(N([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2N=C1[H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])N([H])OC([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C2=C(C([H])=C(S2)C(C(=O)N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C2=C1C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N1C2=C(C([H])=C1C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)N([H])C([H])=N2
[H]C1=C([H])C([H])=[N+]2C([H])=C(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C(=C([H])C2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])OC1=C([H])C(F)=C([H])C2=C1OC([H])([H])C([H])([H])C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]C1=C(SC(=C1[H])C1=C([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C(=O)C([H])([H])[H]
[H]N(C1=NC(=C([H])S1)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])[C@]2([H])C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])[C@]12[H]
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[H]N1N=C(C([H])=C1C(=O)N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])[C@@]1([H])C2=C(OC3=C1C1=C(C([H])=C([H])C([H])=C1[H])C([H])=C3[H])N=C1C(=C2N([H])[H])C([H])([H])C([H])([H])C1([H])[H]
CC1CCCCC1C(=O)N1CCN(CC1)C1=NN=C(C=C1)C(=O)NCCC1CC1
[H]N1N=C(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])N(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=N1)C([H])=C([H])C([H])=C2[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=C2[H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=N[C@@]([H])(C#CC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C1SC([H])=C2[H]
[H]S\C(=N\C1=C([H])C([H])=C(N=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=C(/[H])C([H])([H])C1=C(O[H])C2=C(C(=C1OC([H])([H])[H])C([H])([H])[H])C([H])([H])OC2=O)\C([H])([H])[H]
[H]C1=C([H])C([H])=C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])[C@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C1=NC2=C([H])C([H])=C(OC3=C([H])C(=NC([H])=C3[H])C3=C([H])N=C(N3[H])C(F)(F)F)C([H])=C2N1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
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[H]N(C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C(=C2N=C1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C#CC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C(=C(N([H])C(=O)N([H])C2=C(C3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C([H])=C3[H])C3=C(N=C([H])C([H])=C3[H])N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C1=C2N=C([H])C([H])=C(C2=C(OC2=C([H])C(F)=C([H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=C([H])C([H])=NC(=N2)N([H])C(=O)C([H])([H])[N+]2=C(C([H])=C(C([H])=C2C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1F)C([H])([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
COC(=O)NCC1=CC=C(Cl)C(CN(C2CC2)C(=O)[C@H]2CNCC[C@@H]2C2=CC=C(OCC3=CC(=NO3)C3=C(Cl)C(F)=CC=C3F)C=C2)=C1
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C2=C1C(=O)C1=C(N([H])N=C21)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1N=C(C2=NC3=C(N2[H])C([H])=C([H])C([H])=C3C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=C([H])C(=C([H])N=C12)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])N=C1[H]
[H]N(C(=O)C1=C2N([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C(N2N=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C2=C(N([H])[C@@]([H])(N([H])S2(=O)=O)C2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C3=NC(=C([H])C(=C3N=C2C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1Cl
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])N=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N(C1=C(N=C(O1)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C#N)C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=NN([H])C2=C1C([H])([H])N(C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C1=NC([H])=NC2=C1OC([H])=C2[H]
[H]N([H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N2[C@]([H])(C(=O)N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(\C#N)=C(/[H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])O1)C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C(=O)[C@@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])OC1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C([H])=C2[H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C(N([H])N=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1Cl
[H]OC(=O)C(=O)N([H])C1=C([H])C([H])=C2C3=C(C4=C([H])C([H])=C(C(F)=C4N3[H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=O)OC(C2=N1)(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])N=C(C([H])=C1OC1=C([H])C([H])=C(Cl)C([H])=C1OC([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])[C@]([H])(F)[C@]([H])(C([H])([H])N(C(=O)N2C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])[C@@]([H])(C2=NC(=NN2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(F)C([H])=C([H])C(F)=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C(OC([H])([H])[H])C([H])=C(F)C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C(=O)O[C@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@]1([H])C([H])([H])[H]
[H]C1=C(SC2=C1[C@]1(O[C@@]([H])(OC([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C#N
[H]N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])S(=O)(=O)C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(Br)O1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])O[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N\C([H])([H])C([H])([H])[H])\N([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N\C([H])([H])C([H])([H])[H])\N([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C#N)C1=NN=C(S1)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C2N=C(C([H])=C(C2=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
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CCN(CC)C(=O)CC1=C2N=C(C)C(Cl)=C(C)N2N=C1C1=CC=C(OCCF)C=C1
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[H]S\C(=N/N=C(/C1=C([H])C(Br)=C([H])C([H])=C1[H])C([H])([H])[H])N([H])[H]
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[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])N1C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N(C(=O)N(C1=C([H])C([H])=NC(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(SC([H])([H])C(=O)N2[H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(N([H])C(=O)C2=C(O[H])C3=C([H])C(=C([H])C([H])=C3N=C2O[H])[N+]([O-])=O)C([H])=C1[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
CCC1=C(C=CC=C1CCN1CC(C1)C(O)=O)C1=NSC(=N1)C1=CC=C(CC(C)C)C(=C1)C#N
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[H]N(C(=O)C1=C([H])C(=NC([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C2C([H])=C([H])N([H])C(=O)C2=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C(SC([H])([H])[H])S1)C1=NC(=C([H])S1)C1=C(OC([H])([H])C([H])([H])C([H])([H])[H])N(N=C1[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=NC2=C(SC3=C([H])C([H])=C(Cl)C([H])=C23)C(=O)N1[H]
[H]OC(=O)C1=C([H])\C(=N\C(\S[H])=N\C([H])([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])[C@]([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C([H])C1=C1C2=C(OC3=C1C([H])=C([H])C(O[H])=C3[H])C([H])=C(O[H])C([H])=C2[H]
[H]N([H])C([H])([H])[C@@]12C(=O)N(C3=C1C(N([H])C(=O)C2([H])[H])=C([H])C([H])=C3[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C3C(=C([H])C2=N1)C([H])([H])[C@@]1(C(=O)N([H])C2=C1C([H])=C([H])C([H])=N2)C3([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N([C@]1([H])C(=O)N(C([H])([H])C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C2=C(O1)C([H])=C([H])C(Cl)=C2[H]
[H]OC1=C([H])C([H])=C2C(ON=C2C2=C3C([H])=C([H])C([H])=C(O[H])C3=C([H])C([H])=C2[H])=C1[H]
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[H]N(C(=O)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
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CC(N1C=NN=C1C1=C(Cl)C(Cl)=CC=C1)C1=CC=CC=C1
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[H]N([H])S(=O)(=O)C1=C([H])C2=C(O1)SC(=C2[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=C(OC([H])([H])[H])C(=O)C2=C(N=C(C([H])=C2[H])C([H])([H])[H])C1=O
[H]N(C1=C2C([H])=C(SC2=NC([H])=N1)C1=C([H])SC(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C(Cl)=C1[H]
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[H]N1C2=C([H])C(C#CC3=C([H])C([H])=C([H])C([H])=C3[H])=C(OC([H])([H])C#N)C([H])=C2N=C(C2=C([H])C([H])=C([H])C(=C2[H])N2C([H])=NC([H])=C2[H])C([H])([H])C1=O
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[H]C1=C(C2=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C2([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=NC2=C([H])C(Cl)=C([H])C([H])=C2C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C1=C([H])C(=C([H])C2=C1OC(=C([H])C2=O)C1=C([H])C([H])=C([H])C(\C([H])=C(/[H])C2=NC3=C(C([H])=C([H])C([H])=C3[H])C([H])=C2[H])=C1[H])C([H])([H])[H]
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[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(\N=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=NC(=NN1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])(C(=O)N([H])[H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C(N=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])N=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C2=NC3=C(C([H])=C([H])C(N([H])C(=O)C([H])([H])[H])=C3[H])C([H])=C2C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C2C(O[H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(C1=NN=C(O1)C1=C([H])N=C([H])C([H])=C1C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC(=O)[C@]([H])(C([H])([H])C1=C([H])C(C(=O)N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(O1)C([H])([H])N(C(=O)N1OC(=O)C(=C1C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
COC1=CC=C(C=C1C1=C2C=CC(OC3=CC=C(F)C=C3F)=NN2C=CC1=O)C1=NN=C(C)O1
[H]OC([H])([H])C1(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]2([H])C3=C([H])C(OC([H])([H])C4=NOC(=N4)C4=C(F)C([H])=C([H])C([H])=C4[H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C1=C([H])N(C2=C(C([H])=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C1C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])=C2[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])N([H])C1=O
[H]N([H])C([H])([H])C([H])([H])C1=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(Cl)C(=C2[H])C(F)(F)F)C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C([H])C(C3=C([H])C(=C([H])C([H])=C3[H])C(=O)C([H])([H])[H])=C(C([H])=C2C(=N1)N([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NOC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])S[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C(OC2=C(C([H])=C(C([H])=C2C([H])([H])[H])N2N=C([H])C(=O)N([H])C2=O)C([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C(S1)C([H])([H])N([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])[H]
[H]N(C1=NC([H])=C(S1)C#N)C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C2N=C(N([H])C2=NC([H])=C1[H])C1=C([H])SC([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C(C#N)C([H])=C(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N=C(S1)C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([O-])=O
[H]OC(=O)C1=C(OC2=NC(OC3=C([H])C([H])=C([H])C(=C3[H])C(=N[H])N([H])[H])=C(F)C(N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2F)C([H])=C([H])C(=C1[H])C(=O)N([H])[C@@]([H])(C([H])([H])O[H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C2N(C(SC([H])([H])C([H])([H])[H])=NC2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C(=O)N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)C1=NC2=C(O1)C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])N=C2N=C1C([H])([H])OC([H])([H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(Cl)C(=C([H])S1)C([H])([H])N(C1=NC([H])=C([H])O1)C([H])([H])[H])C1=C(C([H])=C(Cl)C([H])=C1OC([H])([H])[H])C(=O)N([H])C1=NC([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2C(=C1F)C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C3(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1=O)C2([H])[H]
[H]N1C(=S)N(C(=O)C1(C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])[H]
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[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])C([H])(F)F)C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C(=C([H])C(=C1[H])C(=O)C([H])([H])[H])C(=O)C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C2=C(F)C(F)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
NC1=CC=C(SC2=CC=C3C4=C(NCCCC5=CC=CC=C5)C(=O)N=C4C4=C3C2=CC=C4)C=C1
[H]N(C(=O)[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]S\C(=N/C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=NN=C(S1)S(=O)(=O)N([H])[H]
[H]S\C(=N/N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1N=NC2=C([H])C([H])=C(C([H])=C2C1=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(S2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(Cl)=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C(=C([H])C([H])=N1)C1=C(C2=NC([H])=C([H])C([H])=C2N1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C(Cl)=C2C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]O\C(=N/C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=O)N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C2=O)C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]O\N=C(\C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])S2)C([H])([H])C1([H])[H]
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[H]C1=C2N(C(=O)C(=O)C2=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC1=C([H])C(F)=C([H])C(F)=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
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[H]C1=C(N=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(Cl)=C(N(C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H])C(F)(F)F
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[H]N(N([H])C(=O)C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([S-])=S
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[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N([H])C2=NC([H])=C(C([H])=C12)C1=C([H])C([H])=C([H])N1[H]
[H]OC1=C([H])C([H])=C2C(C([H])=C([H])C(C3=C([H])C([H])=C(C([H])=C3[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])=C2OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])=C1[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]C1=NN=C2N1[C@@](C(=O)N2C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2N=C(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C1([H])[H]
[H]N(C1=NN(C2=C1C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C(F)(F)F)C([H])([H])C(=O)N([H])C1([H])C([H])([H])N(C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
NS(=O)(=O)C1=CN(C=CC1=O)C1=C2N=CNC2=NC=N1
[H]OC(=O)C1=C(C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2Cl)C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C2N=C(N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C(=O)C1=C([H])C2=C(N=C([H])C([H])=C2[H])N1C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C1=NC(=NC(=N1)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])N([H])[C@@]([H])(C(=O)O[H])C([H])([H])O[H])C([H])([H])O[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(OC1([H])[H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])N(C1=O)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
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[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC(=O)[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C(C([H])=C(C([H])=C1[H])[N+]([O-])=O)S(=O)(=O)N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=O)N(C(=O)C2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(OC3=C(C(=NN3C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C2=O)=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C2([H])[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C(OC([H])([H])[H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C2=C(N=C([H])N=C2C([H])=N1)N([H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N([H])C(=O)N(C1=C2N=C([H])N(C2=NC(=N1)C1=C(C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C1[H]
CCOC1=CC(=CC=C1Cl)N1CCN(CC1)C(=O)CN1N=C(C(Cl)=C1C)C(F)(F)F
[H]O[C@@]1([H])[C@@]([H])(OP(=O)(O[H])O[H])[C@@]([H])(O[C@]1([H])C([H])([H])O[P@](=O)(O[H])O[P@](=O)(O[H])OP(=O)(O[H])O[H])N1C([H])=C([H])C(=O)N(C1=O)C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C(C([H])=C(O[H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C(OC2=NC([H])=NN3C([H])=C([H])C(=C23)C([H])([H])[H])C(F)=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C(=O)N([H])[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])P([O-])(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C([O-])=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N(C1=C2N([H])C([H])=C(C2=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]C1=C([H])C2=NC(=NC(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C2C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C(F)C(=C([H])C([H])=C12)C1=C(F)C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])N=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2ON=C(N([H])[H])C2=C1[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C(O[H])C([H])=C2C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]OC1=C(\N=N\C(=O)C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
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[H]N([H])C(=O)C1=C2N([H])C3=C(C([H])=C(OC([H])([H])C([H])([H])N([H])[H])C([H])=C3[H])C([H])([H])C([H])([H])N2N=C1C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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OB(O)C1=CC=CC=C1
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[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1Br)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]2(C([H])([H])N(C3=C(C(=NC([H])=N3)N([H])[H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N([H])C(=O)[C@]([H])(N([H])C1=NC(N([H])[H])=C2C([H])=NN(C2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C(=N1)C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=N/C1=C([H])C([H])=C([H])N=C1C([H])([H])[H])C1=NC(SC([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)=C(C#N)C([H])=C1[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NSC(=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(OC([H])([H])[H])C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C2=C(N=C([H])N2[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=C(SC2=C1C1=C(C(=N2)C2=C([H])C([H])=C([H])O2)C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(OC([H])([H])C([H])([H])C2=C([H])C4=C(N2[H])C([H])=C([H])C([H])=C4[H])N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C1=C([H])C(=O)OC2=C([H])C([H])=C(Cl)C([H])=C12)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(=O)N([H])C1=C([H])C(=C(OC2=C([H])C(=C(O[H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=NC(C2=NN=C(O2)C2(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C([H])([H])N(C1=C([H])C([H])=C([H])C([H])=C1Cl)S(=O)(=O)C([H])([H])[H])C1=C(Cl)C([H])=C([H])C(Cl)=C1[H]
[H]O[C@]([H])(C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(N([H])[H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2S(=O)(=O)C([H])([H])[H]
[H]N1C(C([H])=C2C(=O)N([H])C(=S)N([H])C2=O)=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)C1=NOC(=C1[H])C1=C([H])C([H])=C([H])C(\C([H])=C(/[H])C([H])([H])OC2=C([H])C([H])=C([H])C(O[H])=C2C(=O)N([H])C([H])([H])[H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]
Cc1ccc(cc1)-c1csc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2ccccc2)n1
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=NC2=C([H])C(=C([H])C([H])=C2N1C([H])(C([H])([H])[H])C([H])([H])[H])N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(N=C2[H])C([H])([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
CCNC(=O)C1=CC=C2N=C(C)C3=NN=C(N3C2=C1)C1=NC=CC=C1
NS(=O)(=O)C1=C(F)C(F)=C(SCCC(O)=O)C(F)=C1F
[H]C1=C([H])C(=C2C(=O)N(C([H])([H])OP(=O)(OC([H])([H])C([H])([H])[H])OC([H])([H])C([H])([H])[H])S(=O)(=O)C2=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])N(C(=O)C([H])=C1[H])C1=C([H])C(F)=C(C([H])=C1[H])N1C(=O)[C@@]([H])(N(C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C3C([H])=C(Cl)C([H])=C([H])C3=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]12C(=C([H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C(Cl)=C2F)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])N=C(O2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC(=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C(C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC2=C(N([H])C([H])=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C(Br)=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]N(C1=NC2=C(S1)C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C(F)C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]2(C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C1([H])[H]
[H]OC1=C(C([H])=C2C([H])=C([H])C(=O)OC2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]([H])(O[H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=NC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(OC([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C(N([H])C3=NC([H])([H])[C@]([H])(F)C([H])([H])N3[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]12ON=C(C3=C([H])C(=C([H])C([H])=C3[H])[N+]([O-])=O)[C@@]1([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)[C@]([H])(C1=C([H])N(C2=C([H])C(=C([H])C([H])=C12)C(=O)OC([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])SC1=NC2=C([H])C([H])=C(C([H])=C2C(=O)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])=C([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1N([H])C1=C(N([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])[H])C(=O)C1=O)C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[C@]1([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])[C@]([H])(OC(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(N=C1N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])=C([H])C(=C2[H])[N+]([O-])=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C(=O)O[C@@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])C([H])([H])[C@@]([H])(C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(=NN(C1=O)[C@]([H])(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])N=C1C(F)(F)F
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])O[H])[C@]([H])(O[H])[C@]1([H])O[H]
CCCNC1=CN=C2N([C@@H](C[C@@]2(C)CC)C(=O)NCC2=CC=C(C=C2)C(N)=N)C1=O
[H]N(C(=O)C#CC1=C([H])C([H])=C([H])C([H])=C1[H])[C@]12C([H])([H])C([H])([H])C(=O)[C@]3([H])OC4=C5C(=C([H])C([H])=C4OC([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@@]235
[H]N1C([H])([H])C([H])([H])[C@@]([H])(N2C([H])=C(C3=C([H])C([H])=C([H])N=C23)S(=O)(=O)C2=C(Cl)N=C3SC([H])=C([H])N23)C1([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])[H])[C@@]([H])(N1C2=C(C([H])=C([H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]C1=C([H])C(C(=O)C2=C([H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C3=C2C([H])=C([H])C(=C3[H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C2N1[C@]([H])(SC2([H])[H])C1=C([H])\[N+](=N\C(=O)C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(N([H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)=C([H])C([H])=C1[H]
[H]N([C@]([H])(C1=NC([H])=C(N1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C(=O)N([H])S1(=O)=O)S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N(N([H])C(=O)C1=NN([H])C(=C1[H])C1=C([H])C([H])=C(O1)C([H])([H])[H])C(\[H])=C1/C([H])=C([H])C([H])=C([H])C1=O
[H]N(C(=O)C1=C([H])OC([H])=C1[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)S(=O)(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)N(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(SC#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C(Br)C([H])=C([H])C2=C1[H]
[H]OC1=C([H])C([H])=C(N([H])C(\[H])=C2\S\C(N(C2=O)C([H])([H])C([H])([H])[H])=C(\C#N)C(=O)OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
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[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C(S1)C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C2=C(C(=NN2C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
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[H]C1=NC(=NC2=NC(=C([H])C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])=C([H])N=C(N([H])C([H])([H])C(F)(F)C2=NC([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N1N=C([H])N=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[S@@](=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H])C([H])([H])[H]
[H]N(C(=O)C1=C(F)C2=C(N1[H])C([H])=C([H])C(Cl)=C2[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=NC2=C(S1)C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C(=O)C([H])([H])C([H])([H])[C@@]12OC([H])([H])[H]
[H]N1C(=O)C([H])=C(C2=C([H])C([H])=C(F)C(F)=C12)C([H])([H])N1C2=NC([H])=C([H])N=C2N=C1C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C([H])N1C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C1=C([H])N(N=N1)[C@]1([H])C(=O)N(C([H])([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(N([H])C2=NC([H])=NC3=C([H])C(OC([H])([H])C4([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C4([H])[H])=C([H])C([H])=C23)C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])S1)C1=C2C([H])=C([H])N([H])C2=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])N1C(=O)N([H])C(=O)C1(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1OC1=NC(OC2=C([H])C([H])=C([H])C(=C2[H])C(=N[H])N([H])[H])=C(F)C(N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(O[H])N2C(=NC3=C2C([H])=C([H])C([H])=C3[H])N=N1
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[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C2([H])C([H])([H])C2([H])[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N2C([H])=C([H])N=C2C(=N1)N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C1=NC(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C(C#N)C(=C1C#N)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(O[H])N=C2C(=N1)C([H])=C(Br)C(=C2[N+]([O-])=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C([H])=C([H])C(=O)OC2=C1C(=O)C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])C(=O)N(C2=C(C([H])=C([H])C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C(N2C([H])=C([H])C([H])=C([H])C2=N1)C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C2C(=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])[N+]([O-])=O)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C2=C(C#N)C3=NN=C(N3C([H])=C2[H])C([H])([H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])S1)C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC2=C3C([H])=C([H])N(C3=NC([H])=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
FC1=C(C=C(CC2=NNC(=O)C3=C2C=CC=C3)C=C1)C(=O)N1CCC(CC1)C(=O)N1CCC2=C3C1CNC(=O)C3=CC=C2
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])N=C(C([H])=C1[H])C([H])([H])[H]
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CS(=O)(=O)C1=CC(=CC=C1)C1=CC(NC2=CC=C(OC(F)(F)F)C=C2)=NC=N1
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=NN(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C(N=C([H])C2=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C(SC2([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N1C(=O)N(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[N+]1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C3OC4=C(C([H])=C([H])C(=C4[H])[N+]([O-])=O)C3=C2[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]N(N([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C(\[H])=C1/N=C([H])C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC(C2=C([H])C([H])=C([H])O2)=C(C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C([H])=C([H])C(=O)N([H])C1=C([H])C2=C(N=C([H])N=C2C([H])=C1OC([H])([H])C([H])([H])[H])N([H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]N(C1=NC(=NC([H])=C1C1=NN([H])N=N1)N([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C1=C([H])C([H])=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C(=O)OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1S2(=O)=O)C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]12C([H])([H])C(=O)[C@@]3([H])O[C@]3(C(=O)OC([H])([H])[H])[C@]1(C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]1(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]3([H])C([H])=C([H])C([H])([H])OC([H])([H])[C@]3([C@]([H])(OC(=O)C([H])([H])[H])C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]12[H]
[H]OC([H])([H])[C@]12C([H])([H])C([H])([H])[C@@]([H])(C(=C([H])[H])C([H])([H])[H])[C@]1([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C2=NC([H])=C([H])C([H])=C2N1S(=O)(=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N1[C@]([H])(SC([H])([H])[C@@]1([H])C(=O)C1=C([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=C(\[H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H])\C1=C([H])N=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
NS(=O)(=O)C1=CC=C(NC(=O)C(\C#N)=C(\S)NC2=CC=CC=C2)C=C1
[H]N(C(=O)C1=C([H])C([H])=C(Br)O1)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2C(F)(F)F)C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C([H])=NC(=C([H])C2=N1)C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C1=C(N([H])C([H])([H])[H])C(=O)C1=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(N([H])C(=O)C2=C(O[H])C3=C([H])C(=C([H])C([H])=C3N=C2O[H])C2=C([H])SC3=C2C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])C([H])([H])C([H])=C([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])=C([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]C1=NN=C(N1C([H])([H])[H])[C@@](C1=C([H])C([H])=C(Cl)C([H])=C1[H])(C1=C([H])C([H])=C2N(C(=O)C([H])=C(C3=C([H])C(Cl)=C([H])C([H])=C3[H])C2=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(N=NN2C2=C1SC([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])C([H])([H])[C@]2(O[H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])C(=O)[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@]([H])(N([H])C(=O)C([H])([H])N1C([H])([H])C4(C([H])([H])C4([H])[H])C([H])([H])N(C4=C(Cl)C([H])=C(Cl)C([H])=C4Cl)S1(=O)=O)[C@]([H])(C3([H])[H])C2([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[C@]2([H])OC([H])([H])C([H])([H])N(C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C(C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])[H])C([H])([H])[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C1(N([H])C(=O)[C@@](N([H])C(=O)O[C@@]2([H])[C@@]3([H])C([H])([H])[C@]4([H])C([H])([H])[C@]([H])(C3([H])[H])C([H])([H])[C@@]2([H])C4([H])[H])(C([H])([H])[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
FC(F)(F)OC1=CC=CC(SC2=NN3C(C=C2)=NN=C3C2=CN=CS2)=C1
[H]OC(=O)C([H])([H])C1=C([H])C(=O)OC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]2([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
NC(=O)C1=CC2=NC=NC(N3CCC(CN4CCCC4)CC3)=C2S1
[H]OC(=O)C([H])([H])C([H])([H])N1N=C(C(\C([H])=C(/[H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1[H])C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C(O[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N=C(N1C1=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C(=O)N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])[C@@]([H])(C([H])([H])OC([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H]
[H]OC(=O)C(=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])\C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@](C1=C([H])C([H])=C(C([H])=C1[H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)(C([H])([H])[H])C(F)(F)F
[H]N([H])S(=O)(=O)C1=C([H])C(=C([H])S1)C(=N\OC([H])([H])[H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(C(=O)N([H])C([H])([H])[H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(OC3=C(C([H])=C([H])C(Br)=C3[H])S2(=O)=O)=C1[H]
[H]N1C2=C(C3=C1C1(C([H])([H])N(C([H])([H])[H])C1([H])[H])C([H])([H])N([H])C3=O)C([H])([H])C([H])([H])C1=C2N=C(N=C1[H])C1=C([H])N=C(F)C([H])=C1[H]
[H]N(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1[H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])SC(=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NC([H])=C([H])S1
[H]OC1=C2C(=O)OC([H])([H])C2=C(C(OC([H])([H])[H])=C1C([H])([H])C([H])([H])O[P@@](=O)(O[H])C([H])([H])C([H])([H])SC1=NC2=C(N=C([H])N=C2N([H])[H])N1[C@@]1([H])O[C@@]([H])(C([H])([H])O[H])[C@]([H])(O[H])[C@]1([H])O[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
Cl[H].COCCCOC1=CC(=CC=C1OC)C(=O)N(C[C@@H]1CNC[C@H]1CC1=CC=CC=C1)C(C)C
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])=O)N([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(=C2[H])C(=O)C([H])([H])[H])N(C2=C1C([H])=C1C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(Br)=C(N([H])C(=O)C([H])([H])[N+]2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2(C([H])([H])N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])N1N=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N2C(=C1[H])[C@]([H])(N(C(=O)C([H])([H])N(C(=O)[C@]([H])(Cl)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C2C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])N(N=C1C([H])([H])C1=C([H])C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(N=C(N2C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=NC([H])=C(Br)C([H])=C3N(C(=O)C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=N1
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[H]OC([H])([H])C1=C([H])C([H])=C2C(OC([H])=C2C2=C(C(=O)N([H])C2=O)C2=C([H])N(C3=C([H])C([H])=C(F)C([H])=C23)C([H])([H])[H])=C1[H]
[H]N([H])C(=NC(=O)C1=C([H])C([H])=C(O1)C1=C(OC([H])([H])[H])C([H])=C([H])C(Br)=C1[H])N([H])[H]
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[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=NO[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C2=NC([H])=C([H])N2[H])C1([H])[H]
[H]O\C(OC([H])([H])C([H])([H])[H])=C1\C(=NC(=C(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]1([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])OC([H])([H])C([H])([H])N1C(=NC(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=NC(=N1)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)[C@]([H])(C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])C#CC1=C([H])C2=NC(N([H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])N=C2C([H])=C1[H]
[H]N(C1=C2C(=NC([H])=N1)N([H])C(=O)\C2=C(\[H])C1=C(C([H])=C(N1[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=C(N=C(S1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N([H])C1=C([H])N=C([H])C(=N1)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])[C@@]1([H])OC([H])([H])[C@]2([H])[C@]([H])(OC(=O)[C@]12[H])C1=C([H])C(O[H])=C(O[H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=NC(=C([H])C(=C2N=C1C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])N=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
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[H]N([H])C1=NC2=C(OC3=NC([H])=C(Cl)C([H])=C23)C(=N1)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
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[H]OC1=C(Cl)C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=S)N([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N([H])C(=O)C([H])([H])C1=C([H])N(C2=C([H])C([H])=C(C([H])=C12)C1=C([H])C([H])=C(F)C(Cl)=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C(OC([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C(Br)=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C(C([H])=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)C1=C([H])C(C#CC([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=NC4=C(S3)C([H])=C([H])C([H])=C4[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1Br)C([H])([H])N(N1C([H])=NN=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(F)=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)N2OC(=O)C(=C2C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C(=O)N([H])C1=C([H])C2=C(N=C([H])N(C2=O)C([H])([H])C2=C([H])C([H])=C(Cl)C(=C2[H])C(F)(F)F)C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=NC3=C([H])C(=C([H])C([H])=C3N2C([H])([H])[H])C([H])([H])N2C(=NC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C(C([H])=NC2=NC(Cl)=C([H])C([H])=C12)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2OC1=O
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)C2=C(C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C1=O
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])SC([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(OC2=NC([H])=NC3=C2C(=C([H])S3)C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C(F)=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C2C(=NN1[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1C2([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C1=C2C(SC(=C2C([H])([H])[H])C([H])([H])[H])=NC([H])=N1)C([H])([H])[C@@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2[H])C(=O)N([H])C([H])([H])C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C([H])C(Cl)=C([H])C([H])=C3C2=O)C([H])([H])C1([H])[H]
[H]N(C1=C(C2=C(N([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C1=C(C#N)C([H])=NC([H])=C1\C([H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)N(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])[C@@]3([H])N(O[C@@]4(C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C2=C(OC(=C2C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NC2=C(C3=C(Cl)C([H])=C([H])C([H])=C3Cl)[N+]([O-])=C([H])C([H])=C2C(=C1[H])C1=C([H])C([H])=C(F)C([H])=C1Cl
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])N1C(=C(C(=C1C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1(C(=O)O[C@@]2([H])C([H])([H])[N@+]3(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C3([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]SC([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C(N=C(N1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1F
[H]OC(=O)C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])C1=C(C([H])=C(N=C1[H])C1=C(F)C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C#CC([H])([H])OC2=NSN=C2[C@]23C([H])([H])[N@@]4C([H])([H])[C@@]2([H])[C@@]3([H])C4([H])[H])C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C([H])N=C12)N([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=NOC(=C1[H])C([H])([H])[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])C1(OC([H])([H])[H])C([H])([H])OC1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C2C(=O)C(=O)N([H])C(=O)C2=C([H])C([H])=C1[H]
[H]N(C([H])([H])[C@@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H])S(=O)(=O)C1=C([H])C(Br)=C([H])C2=C1N(C(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N1N=NC(=N1)C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])OC1=C([H])C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]N(N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C(OC([H])([H])[H])C(=NC2=C([H])C(F)=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)N([H])C(=O)C(OC2=C([H])C([H])=C(OC3=C([H])C([H])=C(C([H])=C3[H])C3=NC(=NO3)C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])(C1=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]C1=C(OC([H])([H])[H])C(=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C(F)(F)F
[H]N1C(=O)N([H])C(N2C([H])([H])C([H])([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])=C(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C(N=C(OC2=C([H])C([H])=C([H])C([H])=N2)C(=N1)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])F
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C2C(=NC3=NC(N(C([H])([H])[H])C([H])([H])[H])=C(C#N)C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C#CC([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C2=C(N=C(N([H])C2=O)C([H])([H])[H])C([H])=C1Br
[H]C1=C([H])C(=C([H])C([H])=C1N1N=C(C2=C1C([H])([H])C([H])([H])OC2([H])[H])C(F)(F)F)C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]O[C@](C1=C([H])C2=C([H])C(=C(C([H])=C2N1[H])C(F)(F)F)[N+]([O-])=O)(C([H])([H])[H])C([H])([H])SC1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
COC1=CC=C(N2C=C(N=C12)C(F)(F)F)C1=NN(CCCCOC2=C(F)C(F)=C(C=C2)C2=NNC(=O)C2(C)C)C(=O)C1(C)C
[H]OC([H])([H])C([H])([H])N([H])C1=C([H])C(=NC([H])=C1[H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]1(O[H])C2=C(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])=C([H])C(=C2[H])C(=O)C([H])([H])[H]
[H]N1N=NN=C1C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C(=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=S)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[P@](=O)(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C(N2N=C(C([H])=C2N=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]2(C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C1([H])[H]
[H]OC1=C(N([H])C([H])=O)C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1N=C(C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1=O
[H]C1=C(F)C([H])=C(C(=C1[H])[C@]1([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=NOC(=N1)C(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C2=C([H])C(F)=C(Cl)C([H])=C2[H])C1([H])[H])C([H])([H])OC(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
CN1CCN(CC1)C1=CC=C(C=C1)C(=O)NC1=NNC2=C1SC(=C2)C(=O)N[C@H](CN1CCOCC1)C1=CC=CC=C1
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C(SC([H])=C1[H])C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C(OC([H])([H])C(=O)O[H])C(Br)=C(S1)C1=C([H])C(N([H])C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C([H])S1)C([H])([H])S(=O)(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C#N
[H]OC(=O)[C@]([H])(C(=O)C([H])([H])[H])C1=C(Br)C(O[H])=C(O[H])C2=C1N(C(=C2C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(=C2N=C(SC2=C1C([H])([H])[H])N([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C(SC([H])([H])C2=C([H])C(=C([H])C([H])=C2OC([H])([H])[H])C(=O)C([H])([H])[H])=NC2=C([H])C([H])=C(F)C([H])=C12
[H]N(C(=O)[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])N=C2N1C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])N(C(=O)S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C2[H])C([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C2=C(SC(=C2[H])S(=O)(=O)N([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])O[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=NC(N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C(C([H])=N3)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C2C([H])=C(SC2=N1)C([H])([H])C([H])([H])[H]
NC1=NC(=CC=N1)N1C=CC2=C1C=C(C=C2)[N+]([O-])=O
[H]C1=C([H])C(=C(C([H])=C1[H])C1(C2=NN=C3N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C1=C(N([H])C([H])([H])[H])C([H])=C([H])C(C#CC([H])([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C(=O)N(C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]S\C(=N\C1=NN=C(Cl)C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(C(=O)O[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C(ON=C2C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1Cl)C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C1=C([H])C(=C(C([H])=N1)N(C(=O)C(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(N=NN1C([H])([H])C([H])([H])F)C([H])([H])N1C(=O)C(=O)C2=C1C([H])=C([H])C(=C2[H])S(=O)(=O)N1C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NOC(=C1[H])C1=C([H])C([H])=C([H])S1)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(C([H])=C(N2[H])C([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])C(=N1)N([H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
COC1=CC(OC2=NC=NC3=C2N(C)C=C3)=CC=C1NC(=O)NC1=CC(=CC=C1)C(F)(F)F
[H]C1=C(N=C(N=C1C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C#N)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C([H])C([H])=C(C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])[H])C(=O)N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C2=C3C(OC([H])([H])[C@]3([H])C([H])([H])C1([H])[H])=C(Br)C([H])=C2OC([H])([H])[H]
[H]N(C(=O)C1=NC(C#N)=C([H])N1[H])C1=C(C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(O[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C1=NC(C2=C([H])C([H])=C([H])O2)=C2N=C([H])N(C2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C([H])=C2C(=C1[H])N1C(=C(C(=O)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H])N1C(=O)C2=C([H])C(F)=C([H])C([H])=C2N=C1C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C1=C([H])N(N=C1[H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(N([H])C([H])([H])C([H])([H])[H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])S1(=O)=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C2=C([H])N=C(C([H])=C2C([H])=C1[H])C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC([H])([H])C1=C(N(C(=C1C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])N1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=N\C2=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2[H])\N([H])C#N)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C1=NN(C2=NC(=O)C([H])([H])S2)[C@]([H])(C2=C([H])C([H])=C(Br)C([H])=C2[H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2N2C([H])=NC([H])=C12)C1=NN=C([H])N1[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])[N@]1C([H])([H])[C@]1([H])C(=O)OC([H])([H])[H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C(Cl)=C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C2=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(N([H])C2=C1C(=O)C([H])([H])C([H])([H])C2([H])[H])C(\[H])=C1/C(=O)N([H])C2=C([H])C([H])=C(F)C([H])=C12
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=NC(=NO2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(SC2=C(Cl)C([H])=C(C#N)C([H])=C2[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]ON(C(=O)N([H])C([H])([H])C1=NC([H])=C(C([H])=C1F)C1=C([H])C(Cl)=C([H])C(F)=C1C1=NN(N=N1)C([H])([H])[H])C([H])(C([H])([H])F)C([H])([H])F
[H]OC1=C(C(=O)C([H])([H])[H])[C@@]([H])(N(C1=O)C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C([H])([H])C([H])([H])OC([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C(=O)[C@@]1(O[H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])C4=C([H])C5=C(C([H])=NN5C5([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C5([H])[H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])[C@@]([H])(O[H])C([H])([H])[C@]12C([H])([H])[H]
[H]O[C@](C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H][C@@]1([C@@H](C)CC)N(C)C(=O)[C@]([H])([C@@H](C)CC)N(C)C(=O)[C@H](CC(=O)OC(C)(C)C)N(C)C(=O)[C@H](NC(=O)[C@@H](C(C)C)N(C)C(=O)[C@H]2CCCCN2C(=O)[C@@H](C)OC(=O)[C@H](CC2=CC=C(OC)C=C2)NC(=O)[C@H](C(C)C)N(C)C(=O)CNC1=O)C(C)C
[H]N([H])S(=O)(=O)N([H])C1=C(C#N)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C2=C([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])[C@]5([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[C@]45C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C2N(N=C(C2=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N2C3=C(C([H])=C(Cl)C([H])=C3C([H])([H])[C@@]2([H])C([H])([H])C1([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]11N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N([H])C(=O)C1=C([H])C(F)=C([H])C(=C1[H])C(F)(F)F)C(=O)N([H])[C@@]([H])(C1=NC([H])=C(C([H])=C1F)C(=O)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C1([H])[H])C([H])([H])OC(=O)C1=C(C([H])=C(C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=C(N([H])C1=O)C1=C([H])C(=C([H])C([H])=C1[H])N1N=C(C2=C1C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C(F)(F)F
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[H]C1=C([H])C(Cl)=C(C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])([H])[C@@]2([H])C([H])([H])[C@]1([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]OC1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C(=O)C2=C(F)C([H])=C([H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C(=O)OC1=C([H])C([H])=C(OC3=C([H])C([H])=C(C([H])=N3)C(F)(F)F)C([H])=C1[H])C2([H])[H]
[H]O[C@]([H])(C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(C3=C(N(C4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])[H])C3=C2C([H])([H])C([H])([H])C3([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=NC2=C(N=C(C([H])=C2[H])N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C1=NC(=C(S1)C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
COC1=CC=C(C=C1)S(=O)(=O)NCC1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
[H]OC(=O)[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C([H])([H])C(\C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])C([H])([H])[H])=C(\C([O-])=O)C1=C([H])C2=C(OC([H])([H])O2)C(OC([H])([H])[H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC2=C(O1)C([H])=C([H])C(Cl)=C2[H]
[H]OC([H])([H])[C@]([H])(N([H])C1=NC(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NC2=C1N=C(S2)N([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C(OC([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])\C2=C(\[H])C([H])([H])N2C([H])=NC3=C2C([H])=C(C([H])=C3[H])[N+]([O-])=O)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N(C(=O)C(F)(F)F)C([H])([H])C([H])([H])C2=C([H])C(O[H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[C@@]1([H])N(C(=O)[C@@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]N(\N=C1\C2=C(N([H])C(Cl)=C2Cl)C(=O)N([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C(=NC([H])=C2[H])N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C1([H])[H])C([H])([H])[C@@]([H])(O[H])[C@@]1([H])[C@]3([H])C([H])([H])C([H])([H])[C@]([H])([C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])N([H])C4=C([H])C([H])=C(C([H])=C4[H])S(=O)(=O)N([H])[H])[C@@]3(C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])[C@]21[H]
[H]N(C(=O)C1=C(N(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C(C([H])=C2[H])S(=O)(=O)C2=C([H])C([H])=C([H])N=C2[H])C2=C1C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])N2C(=O)[C@](N([H])[H])(C([H])([H])C3=C([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@]([H])(OC([H])([H])[H])[C@]2([H])[C@]([H])(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C2N=C(C([H])=C([H])C2=C1[H])N1C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1Br)[C@]([H])(N1N=C([H])N=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C1=C([H])C(=NS1)C([H])([H])N1C([H])([H])C([H])([H])C(F)(F)C1([H])[H])C1=NC(=C([H])N2C1=NC([H])=C2C1=C([H])N([H])N=C1[H])C([H])([H])[H]
[H]N1C(=NC2=C1C1=C(C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C2C([H])=C([H])C(Cl)=C1[H])C1=C(C#N)C([H])=C([H])C([H])=C1C#N
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=NC(=N1)C#N)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2N=C([H])C(=O)N([H])C2=O)[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC1=NC2=C([H])C(C#CC([H])([H])N3C([H])([H])C([H])([H])C([H])(C([H])([H])C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C2N1[H]
[H]OC1=NC(=NC(=C1N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])N1N=C(C2=C1C([H])([H])C([H])([H])N(C(=O)N([H])[H])C2([H])[H])C1=C([H])C([H])=C(I)C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N(C(=O)C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])N([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)N1C(=O)C(=C(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])N([H])\N=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
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[H]N([H])C([H])([H])C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)O[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(F)C([H])=C2C3=C(C(=O)N(C3=O)C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C(=NC2=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1O[H])N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1[H])C(=O)O[H]
[H]N(C(=O)C([H])([H])OC1=C2C(SC3=NC4=C(S3)C([H])=C([H])C([H])=C4[H])=C([H])N([H])C2=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]OC(=O)C1=NC2=C(C(Cl)=C([H])C(Cl)=C2[H])C(O[H])=C1C([H])([H])C([H])([H])C(=O)O[H]
[H]N=C(N(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C(F)=C(N([H])C(=O)C2=C([H])C(=NN2C2=C(F)C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(O1)C([H])([H])N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C(N([H])C([H])([H])C1([H])[H])=C(C#N)C#N
[H]OC1=C2N([H])C(=O)C([H])([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(SC([H])([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C(N(C([H])([H])[H])C([H])([H])[H])=C(C2=C1OC(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(C#N)=C2[H])[C@]1([H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2C(OC([H])([H])C1=O)(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C([H])C(C#N)=C1[H]
[H]C(=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(\[H])=C(/C([H])([H])[H])[C@@]1([H])[C@]([H])(OC([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@@]11OC1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(F)(F)F)C([H])([H])C([H])([H])C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N1C([H])=C([H])N=C(N([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=O)C([H])([H])C([H])([H])[H])C(=O)C([H])([H])SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=NN(C2=O)C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])O[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])[C@@]2([H])[C@@]([H])(C1([H])[H])[C@@]2(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])OC([H])([H])C(F)(F)F
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=C(C([H])=C(C([H])=C1C(F)(F)F)C(F)(F)F)C(=O)C(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]C#CC([H])([H])N([H])C1=C([H])C([H])=NC2=C1C1=C(S2)C(=O)N(C([H])=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C3=C([H])N=C(\C([H])=C(/[H])C4=C([H])C([H])=C(C([H])=C4[H])C([H])([H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C([H])=C23)C2=C1C([H])([H])C([H])([H])C([H])([H])N([H])C2=O
[H]N([H])C(=O)C([H])([H])N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(N(C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(O[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C(SSC1([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C(=O)O[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N([H])[C@@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(=C(O1)C1=C([H])N2C(=NN=C2C2([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C2=C(N([H])C(=N2)C2=C([H])C([H])=C(Cl)S2)C([H])=C1[H])C1=C([H])C([H])=C(N2C(=O)C([H])([H])OC([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]C(=O)[C@@]1([H])N(C(=O)[C@@]2([H])N(C(=O)C([H])([H])C3([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4C3([H])[H])C([H])([H])SC2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])[C@@]1(OC([H])([H])C2=C(N=C(N=C12)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])N=C(C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=N1)[C@@]1([H])C([H])([H])[N@]2C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])N([H])C1=O)C1=C([H])C(N([H])C([H])([H])[H])=C([H])C(C#N)=C1[H]
[H]N(C1=C(SC2=C([H])C([H])=C([H])C([H])=N2)C([H])=C2C(=O)C([H])([H])C([H])([H])C2=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC([H])([H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])OC([H])([H])[H])C(=O)N([H])C1=NC([H])=C(S1)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C3=C(Cl)C([H])=NC(=C3[H])N3C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])N(N=C4[H])C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C21)C1=C([H])C([H])=C(F)C([H])=C1[H]
COCC1=CC2=C(N1C)C(OC1=CC=C(NC(=O)NC3=CC(=CC=C3)C(F)(F)F)C(Cl)=C1)=NC=N2
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C(=NO1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C(\[H])=C(/C([H])([H])[H])[C@@]2([H])OC(=O)[C@@]3([H])N(C(=O)C(=O)[C@]4(O[H])O[C@@]([H])([C@@]([H])(OC([H])([H])[H])C([H])([H])[C@@]4([H])C([H])([H])[H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])\C(=C([H])\[C@]([H])(C(=O)C([H])([H])[C@]([H])(O[H])[C@@]2([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=NN([H])C2=NN=C(C([H])=C12)C1=C([H])C([H])=C([H])C(F)=C1F
[H]N(C(=O)C([H])([H])OC([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]C1=C([H])C2=C(S1)C(=NC1=C(N=NN21)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1C([H])([H])N(C(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=NC([H])=C([H])O1
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(N([H])C2=NC([H])=C(Cl)C(=N2)C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C(O[H])/C(=N\C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])/C\1=N/C1=C([H])C([H])=C([H])C(C(=O)N(C([H])([H])[H])C([H])([H])[H])=C1O[H]
[H]N([H])C1=C([H])C(=NC(OC([H])([H])C([H])([H])[H])=C1C#N)N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC3=C(OC([H])([H])[H])C([H])=C([H])C(=C3[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C2C([H])=C3[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2C([H])=C([H])S3)C([H])([H])C1([H])[H]
[H]N=C(N([H])C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]OC(=O)C([H])([H])N1C2=C([H])C([H])=C(F)C([H])=C2C(=C1C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N=C(SC([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C2C([H])=NN(C2=NC([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C([H])([H])N2C3=C([H])C([H])=C([H])C([H])=C3N=C2C([H])([H])OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C1C([H])([H])[H])C(F)=C(OC1=NC([H])=NN3C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C(=C13)C([H])([H])[H])C([H])=C2[H]
[H]C1=C([H])C(F)=C([H])C(=C1[H])C(=O)C1=C(C([H])=C2OC([H])([H])OC2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C(=NN2[C@]1([H])C([H])([H])N(C(=O)C([H])([H])Cl)C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1N([H])C(=C(C1=O)C([H])(C1=C([H])C([H])=C(O1)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C(N([H])N([H])C1=O)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(C2=C([H])N([H])C3=C(Br)C([H])=C([H])C([H])=C23)=C(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)[C@]1(C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N(C([H])=C2C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])[N+]([O-])=O)S(=O)(=O)C([H])([H])[H]
[H]C1=C(C2=NSN=C2SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])N1C2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(N1C(=NN=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]N([C@]1([H])C(=O)N(C2=C(F)C3=C(C([H])=C2[H])C([H])([H])N([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C(Cl)C([H])=C([H])C2=C1[H]
[H]N(C1=C(C(=O)OC([H])([H])[H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
CNC1=NC(C2CC2)=C(S1)C1=CC=NC(NC2=CC=CC(=C2)S(N)(=O)=O)=N1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC(=N1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2O1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(\C([H])=C2/SC3=C([H])C([H])=C([H])C([H])=C3N([H])C2=O)C2=C1C(=C([H])C([H])=C2[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(S1)C1=NN=C(O1)SC([H])([H])C(=O)C1=C(N(C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])[C@]2([H])C([H])([H])N(C(=O)C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]C1=NN(N=C1C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]4([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N([H])C([H])([H])[C@]([H])(OC2=C(F)C(OC3=C([H])C(=C([H])C([H])=C3[H])C3=NC([H])([H])C([H])([H])N3C([H])([H])[H])=NC(OC3=C(O[H])C([H])=C([H])C(=C3[H])C(=N[H])N([H])[H])=C2F)C1([H])[H]
FC(F)(F)C1=CC=CC=C1C(=O)N1CCN(CC1)C1=NN=C(C=C1)C(=O)NC1=NC2=C(N1)C=CC=C2
CNC1=NC(=C(S1)C1=CC=NC(NC2=CC=CC(=C2)S(N)(=O)=O)=N1)C(F)(F)F
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C([H])([H])[H])C(=O)C1=NOC(=N1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C1=C(N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O)C1=NC([H])=C([H])O1
[H]ON([H])C(=O)[C@@]([H])(O[H])C([H])([H])N(C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=N2)C(F)(F)F)C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=NN2C(=N1)C1=C(N=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(OC1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=C(N=C([H])C(=N1)N([H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=N1)C([H])([H])[H])C([H])([H])[H]
[H]N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(ON(C(=O)C1([H])[H])C([H])([H])[H])C2([H])[H]
[H]N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N([H])C1=C([H])C2=C(C([H])=C1[H])C(=C([H])N2C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])C(=O)N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C(F)=C1[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C3([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H]
[H]OC1(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])OC2=C([H])C([H])=C3C(=C2[H])C([H])=C(C([H])=C3C2=C([H])OC([H])=C2[H])C2=NC3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(N([H])C3=C2C([H])=C(F)C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(Br)C([H])=N2)C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2C(=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])N3C([H])=NC4=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C4[H])C3=O)C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])N(N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1(N2C(=NC([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C(Cl)=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C(OC([H])([H])[H])C([H])=C(C([H])=C3[H])C3=NC4=C(S3)C([H])([H])C([H])([H])C([H])([H])O4)C([H])=C2C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C(N(C([H])=N1)C([H])([H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C(O[H])=C1[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(Cl)C([H])=NC([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C(=O)O[H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1S2)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@@]([H])(OC1=C([H])C([H])=C([H])C(I)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]N([H])C1=NC2=C([H])C(=C([H])C([H])=C2C(=N1)N([H])[H])C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)C([H])([H])[N+]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])C1=NC([H])=C([H])C3=C1C(=C([H])C([H])=C3[H])C2=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C2=NN=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]\C(=C1/C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC1=NC([H])=C2C(=C1[H])N(C(OC1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])=C2C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C(O[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C(=O)C1(N([H])C([H])([H])C([H])([H])[H])C([H])([H])N(C2=C([H])N=C(C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C(=N2)C2=C([H])C([H])=NC(Cl)=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C(\C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])OC(=O)N1C([H])([H])C2=C(C3=C(S2)N2C(=NN=C2C([H])([H])N=C3C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])[H])C([H])([H])C1([H])[H])=[N+](/[O-])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H]
[H]C1=C([H])N=C(S1)[C@]([H])(OC([H])([H])[H])C1=C([H])C(OC([H])([H])C2=C([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N1C(=O)C(C2=C([H])N(C3=C2N=C([H])C([H])=C3[H])C([H])([H])[H])=C(C1=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@]([H])(C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C(SC2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H])S([O-])(=O)=O
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])[C@@]([H])(N2C(=O)N(C([H])([H])[H])C([H])([H])C2=O)C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1N=C(C2=C(N(C3=C([H])C([H])=C(Br)C([H])=C23)C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1=O)C([H])([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C(C([H])=C2[H])C(F)(F)F)N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C([H])C([H])=C2O1)C([H])([H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])(OC([H])([H])[H])C([H])(OC([H])([H])[H])C([H])([H])C1([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(O[H])C([H])=C(C(=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C2C([H])=C([H])C([H])=C(C3=NC([H])=C([H])S3)C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C2OC([H])([H])C([H])([H])C2=C(C2=C1C([H])([H])C([H])([H])O2)C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(=NN1C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])=NC(=C2C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1C#N
CC1=C(C=CC=C1CN1C2=C(SC(=N2)N2CCOCC2)C(=O)N=C1C1=CC=CC=C1)C(F)(F)F
[H]N(C1=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=NC([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C(N=C1C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=N1)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(N=C(S1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C(N=C(O1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(SC(=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1(OC([H])([H])C([H])([H])O1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C3=C2C([H])=C([H])N3[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C(Br)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N2C([H])=C([H])N=C2C(=N1)N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C2=C(C([H])=C1[H])C1=NC3=C([H])C([H])=C(F)C([H])=C3C(C([O-])=O)=C1SC2([H])[H])C([H])([H])[H]
[H]N([H])C1=C(C([H])=C([H])C([H])=N1)C(=O)C1=NC(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=[N+](C2=C([H])C(Cl)=C1Cl)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC(=O)C([H])([H])[H]
[H]N([H])C(=O)C1=C(O[C@@]([H])(C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])[H])C([H])=C(S1)N1C([H])=NC2=C1C([H])=C(C([H])=C2[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(O[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(OC([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])N1C([H])=C(C(=O)N([H])[C@@]2([H])[C@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C3([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C(=O)C2=C([H])C([H])=C(F)C([H])=C12
[H]\C(\C(\[H])=C(/C(=O)OC1=C2C([H])=C([H])C(OC2=C([H])C([H])=C1C1([H])SC([H])([H])C([H])([H])S1)(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])C([H])([H])[H])=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C(Br)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C1([H])[H])C([H])([H])OC(=O)[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NN=NN1C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C(F)C(F)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(C([H])([H])C2=C([H])C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
CC(=O)NC1=NN(C(C)=O)C(C)(S1)C1=CC=CC=C1
[H]N1C([H])=C(C2=C1C([H])=C([H])C(C#N)=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])=C2C#N)C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C(C([H])=C([H])C([H])=C12)C1=C([H])N=C(C([H])=C1[H])N1C([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])[C@]1([H])C2([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)C([H])([H])N([H])C(=O)[C@]([H])(S[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])[C@@]([H])(C2=C([H])C(O[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C(Br)=C1[H])C1=NN([H])C2=C1C([H])=C(C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])S1(=O)=O
[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(S1)C#CC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])SC2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N([H])C(=O)C([H])([H])[C@]1([H])ON=C(C2=C([H])C([H])=C(N([H])C(=N[H])N([H])[H])C([H])=C2[H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])N(C([H])([H])C(F)(F)F)S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=NC2=C([H])C(Cl)=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N([C@@]1([H])C(=O)N(C2=C(F)C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
Cc1cnc(Nc2cc(Cl)cc(Cl)c2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
CCN(CC)C1=CC=C(CN(C2CCCC2)S(=O)(=O)C2=CC=C(C)C=C2)C=C1
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1(C2=NN=C(S2)C2=NN(C(=C2C2=NN=C(O2)C([H])([H])[H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=C(I)C([H])=C4[H])[C@@]([H])(C([H])([H])[H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])N2C3=C(OC4=C(C([H])=C([H])C([H])=C4[H])[C@]12[H])C([H])=C([H])C(=C3[H])C(=O)C([H])([H])[H]
[H]OC1(C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(F)C(F)=C2N([H])C2=C(F)C([H])=C(I)C([H])=C2[H])C1([H])[H]
[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(N(N=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=O
COC1=CC=C(OC2=CC=C(CN(CC3=CC(F)=CC(F)=C3)C3=C(Br)C=C(CC(O)=O)C=C3Br)C=C2)C(OC)=C1
[H]OC1=C([H])C(=C([H])C([H])=C1Cl)C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=NC([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N=C(N([H])[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C3=C(N=C(N3C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)C(=O)N1C([H])([H])C([H])([H])N(C2=C(Cl)C(=O)N(N=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C2N(C(=O)C([H])([H])[C@]2(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C(F)=C(F)C([H])=C1F
CCNc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(Cl)c1
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[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])[C@@]([H])(OS([O-])(=O)=O)C([H])=C([H])[C@@]4([H])[C@@]([H])(C2([H])[H])[N@@+]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@]314
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[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C(F)(F)F)C([H])([H])C1([H])[H])C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C2=C1OC(=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC([H])([H])C([H])([H])[C@]1([H])C([H])([H])N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)C1([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])C([H])([H])N(C(=O)[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N1C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H]
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CC1=CC(=CC=C1)C(=O)CC(NC1=CC=C(C=C1)N(O)=O)C1=CC=C(C=C1)C(F)(F)F
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[H]N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C2=NC(=C([H])C(=N2)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(N([H])C(=O)[C@@]([H])(S[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
ClC1=CC=C2N=CC(=CC2=C1)S(=O)(=O)NCCCCN1CCN(CC1)C1=CC=CC(Cl)=C1Cl
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(=O)N(C2=C1C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
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[H]OC([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(=C([H])S1)C1=NC2=C([H])C([H])=C([H])C([H])=C2S1
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1O[H])C([H])([H])C([H])([H])C1=C([H])C(O[H])=C(O[H])C([H])=C1[H]
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[H]N(C(=O)C(\[H])=C(/[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2N=C(C([H])=C(C2=C1[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=NOC([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(Cl)=C1[H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])[H]
[H]OC1=C(C([H])=C(C(=C1C([H])([H])[H])C([H])([H])C1=NC([H])([H])C([H])([H])N1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NN1C(=O)C1=C(F)C([H])=C([H])C([H])=C1F)N([H])C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])[H]
COC1=CC(=CC=C1Cl)N1CCN(CC1)C(=O)CN1N=C(C(Br)=C1C)C(F)(F)F
[H]C([H])=C([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])[C@@]([H])(F)C([H])([H])N2[H])=C([H])C(N([H])[H])=C1[H])C1=C([H])C(=C([H])C(=C1O[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C(=O)C([H])([H])SC1=C([H])N=NN1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])N(C([H])=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)[C@]2(C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2(C3=C([H])C([H])=C(OC(F)(F)F)C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@](O[H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C2N(C([H])=NC2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C([H])C(N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N([H])C1=NN([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])C(=NC(=N1)N([H])[H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(C2=C([H])OC([H])=C2[H])C(=NC2=C(C([H])=NN12)C1=C([H])N(N=C1[H])C([H])([H])[H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(S2)C2=C([H])C(OC(F)(F)F)=C([H])C([H])=C2[H])C2=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]OC(=O)C1=C(C(=NN1C([H])([H])C1=C2OC([H])([H])OC([H])([H])C2=C([H])C(=C1[H])C(=O)O[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1Cl
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(N([H])C2=NC(=C3N=C([H])N([H])C3=N2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1[H]
[H]OC1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N(C(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC([H])([H])C1=C2N(N=C([H])N=C2N([H])C2=C([H])C3=C(C([H])=C2[H])N(N=C3[H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])OC([H])([H])C1=C(C([H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]OC([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C2C(N=C(N=C2C2=C([H])C(OC([H])([H])C3([H])C([H])([H])C3([H])[H])=C([H])C(OC([H])([H])C3([H])C([H])([H])C3([H])[H])=C2[H])C2=C([H])C(OC([H])([H])C3([H])C([H])([H])C3([H])[H])=C([H])C(OC([H])([H])C3([H])C([H])([H])C3([H])[H])=C2[H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=N1)C(=O)C1=C([H])C(=C([H])C(=C1[H])[N+]([O-])=O)[N+]([O-])=O
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3N=C(N([H])C3=NC([H])=C2Br)C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=N1)N1C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])[H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(SC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C(F)(F)F
[H]C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(F)=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C(/[H])C2=C([H])C([H])=[N+](C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C([H])=C(S1)C(=O)OC1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])C([H])([H])C1=C([H])N2C([H])=C(SC2=[N+]1C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])[H]
[H]C1=NC(=C(O1)C1=C([H])N2C(=NN=C2C2(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C(F)C([H])=C([H])C(F)=C1[H]
[H]OC1(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)O[C@@]2([H])C([H])([H])C([H])([H])[C@]3([H])N([C@@]2([H])C([H])([H])C([H])([H])C3([H])[H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN=C(O1)N([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N=C1[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C([H])C(=C1N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C1[H])C([H])=C(Cl)C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])[C@@]3([H])N(C(=O)C([H])([H])[H])[C@@]([H])(C2([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]C(=C(Cl)Cl)[C@@]1([H])[C@]([H])(C(=O)OC([H])([H])C([H])([H])N2N=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)C(\[H])=C(/[H])\C(\[H])=C(/[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C(\[H])=C(/[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(N([H])C([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C(F)C(OC([H])([H])C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C(=C1[H])C(F)(F)F)[C@@]1([H])C2=C(N(C(=O)C([H])=C2[H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
COC1=C2N=C(NC(=O)C2=CC(=C1)C1=CNN=C1)C(N)C1=CC=CC(Cl)=C1
[H]O[C@@]([H])(C([H])([H])C(=C([H])[H])C(=O)N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(N=NC(=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C2=NC([H])=C(C#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC([H])=C1C#CC1=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C2N=C3N(N=S=C3N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C2=C1[H]
[H]N(C1=C([H])C([H])=C(Cl)C(F)=C1[H])C([H])([H])C([H])([H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])[C@@]([H])(OC2=C([H])C([H])=C(O[H])C(F)=C2[C@@]1([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])OC(=O)C1=C(Cl)C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(OC3=C([H])C([H])=C([H])C([H])=C3S2)C([H])=C1[H])C([H])([H])[H]
[H]N1N=NC(=N1)C1=C([H])C(\N=C2/SC(=NN2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C2S[C@@]([H])(C([H])([H])[H])C([H])([H])C3=C2C(=C([H])C([H])=C3OC([H])([H])C2=C([H])C([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C(=[N+]=[N-])C(=O)[C@]1([H])C([H])([H])C([H])([H])[C@]2([H])[C@]3([H])C([H])([H])C([H])([H])C4=C([H])C(=O)C([H])([H])C([H])([H])[C@@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@@]12C([H])([H])[H]
[H]OC1=C(C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])C([H])([H])C(=O)[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H])C([H])([H])C([H])=C([H])[H]
NC1=C(SC2=NC(N)=C(C#N)C(=C12)C1=CC=CC=C1Cl)C(=O)C1=CC=CC(Cl)=C1
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])[C@@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(S1)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]\C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])=C1/C(=O)C2=C(Cl)C([H])=C(Cl)C([H])=C2OC1([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)[C@@]1([H])[C@]2([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(Cl)=C3C#N)C([H])([H])[C@]12[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(F)(F)F)C1([H])[H])C1=C([H])C([H])=C(SC2=NN3C([H])=C([H])C([H])=C3C(=N2)N([H])C2=NN([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C2N=C(C([H])=C(N([H])[H])N2N=C1[H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C([H])S1)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@@]1([H])C(=NC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1(N([H])C(=O)C(F)(F)F)C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C(Cl)=C([H])C(Cl)=C1C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]N(C1=C(C2=C(N([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C1=C2C(SC(\C([H])=C(/[H])C(=O)N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2C([H])([H])[H])=NC([H])=C1C#N
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC(=C([H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])N1C(=C(C(=O)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])[C@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N([H])S(=O)(=O)C1=NC2=C(S1)C([H])=C(OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C([H])=C2[H]
[H]OC([H])([H])C([H])([H])OC(=O)C([H])([H])C1=C(N(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C(N1C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])[C@]3(O[C@@]([H])(C4=C3C([H])=C(Cl)C(=C4[H])C([H])([H])[H])C(C#N)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C2=C(F)C([H])=C(F)C([H])=C2[H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(Cl)C([H])=C2C(=O)C(Cl)=C(OC2=C1[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(C2=C1C(=NC(SC([H])([H])C([H])([H])[H])=N2)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]OC(=O)[C@]12C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C5=C(N(N=C5[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
CCCCN1C(C)=C(C)C=C(NC(=O)CC2=CC=CC=C2)C1=O
[H]N(C1=C(C(=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C([H])C1=O)C([H])([H])C(N([H])C(=O)C1=C([H])C([H])=C(Cl)S1)(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])N([H])C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])SSC1([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C2=C(N=C([H])N=C12)N([H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]\C(SC1=C([H])C([H])=C([H])C([H])=C1[H])=C(\[H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=O)C2=C(O1)C1=C([H])C([H])=C([H])C([H])=C1C([H])=C2[H]
[H]N1C(=NC([H])([H])C1([H])[H])C([H])([H])N1N=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)N2OC(=O)C(=C2C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C(=C1[H])N1N=C(N(C1=O)C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[C@@]2([H])OC([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C2([H])[H])C([H])=C1F
[H]N1C(OC([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])=NC([H])([H])C1([H])[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])S[C@]([H])(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])S1)[C@@]([H])(O[H])C(=O)N1C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]SC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]N([H])C(=O)[C@@]1(C2=C([H])C([H])=C(F)C([H])=N2)C([H])([H])C2([H])N(C([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C(Cl)C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=NC(N2C([H])([H])C([H])([H])N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=C2C([H])=C(SC2=N1)C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C2/OC(=O)N(C2=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])[H])C([H])=C1Br
[H]N1C2=NC([H])=C([H])C(=N2)C2=C([H])C(OC([H])([H])C([H])([H])\C([H])=C([H])\C([H])([H])OC([H])([H])C3=C([H])C1=C([H])C([H])=C3OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=NC([H])=C2[H]
[H]OC1=C(C(=O)C2=C([H])C([H])=C([H])O2)[C@]([H])(N(C2=NC3=C(S2)C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C3[H])C1=O)C1=C([H])C([H])=C([H])O1
[H]N1[C@]2([H])C3=C(N(C4=C([H])C([H])=C(C([H])=C34)S(=O)(=O)N3C([H])=C([H])C4=C3N=C([H])C([H])=C4[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]N1C(SC([H])([H])C(=O)OC([H])([H])[H])=NC(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(C#N)C([H])=C([H])C(=N1)N1C([H])([H])[C@@]([H])(C2=C([H])C([H])=C(C#N)C([H])=C2[H])[C@]2(N(C(=O)N(C2=O)C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])[H])C1([H])[H]
[H]C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])C2([H])C([H])([H])C2([H])[H])=C(OC([H])(F)F)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]1([H])C([H])=C([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(N1[H])C([H])=C(Cl)C(=C2[H])C(N([H])[H])=[N+]([H])[H]
[H]N(C(=O)C([H])([H])N(C(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])=C([H])C(=N2)N1C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])OC3=C4C([H])=C([H])C(=NC4=C([H])C([H])=C3OC2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=NC(=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C([H])N([H])C2=C1C([H])=C(OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C2[H]
[H]N([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])N(C(=O)C11C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC(=O)C(\[H])=C(/[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C(C(=C(C([H])=C1C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C(N2C([H])([H])C([H])([H])N(C(=O)[C@@]3([H])C([H])([H])S(=O)(=O)C([H])([H])[C@]3([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C(F)=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(\C1=C([H])N=C([H])N=C1[H])=C1\C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])OC([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)[C@@]1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C1([H])[H]
[H]N1C(=O)OC([H])([H])[C@@]1([H])C(=O)N1C([H])([H])[C@@]([H])(O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(\C(=N\C#N)N([H])C2=C3C([H])=C([H])N([H])C3=C([H])C([H])=C2[H])[C@@]([H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(N=C([H])O1)C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N1C(=C2C(=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])OC([H])([H])[C@]([H])(O1)C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])SC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])N1N=NC(=N1)C1=C([H])N=C([H])C(=C1[H])C1=C([H])N(N=N1)C([H])([H])C1=C([H])C(Br)=C(Br)C(Br)=C1[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C(/C#N)C(=O)N([H])[H])C([H])=C1SC1=NC2=C([H])C([H])=C([H])C([H])=C2S1
[H]C1=C(OC2=C1C([H])=C(C([H])=C2[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C(F)C(F)=C(F)C(F)=C1F
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])N=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C1=C(C(=O)C([H])([H])C([H])([H])N21)C([H])([H])[H]
[H]O\N=C(\C1=C([H])C([H])=C([H])C(=C1[H])C(N([H])C(=O)N([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N(C1=C([H])C(O[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])C(F)(F)F
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=O)O2)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C([H])C(=C3[H])[N+]([O-])=O)S2(=O)=O)C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])O1
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
CC(C)C1=CC=C(NC(=O)OC2=CC=C3N(C)C4[C@@](C)(CC[N]4(C)C)C3=C2)C=C1
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3(N([H])C(=O)N([H])C3=O)C([H])([H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])N1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)C1=C(C(=O)N([H])C1=O)C1=C([H])N([H])C2=C1C(F)=C([H])C([H])=C2[H])[C@@]([H])(O[H])C([H])([H])O[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(O2)C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C2=NOC(=N2)C2=C([H])C([H])=C(C([H])=N2)C(F)(F)C([H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]1=C(C([H])=C(C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C(Cl)C([H])=C2[H])[C@@]2(N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C3=C2N([H])C2=C([H])C([H])=C(F)C([H])=C32)C1=O
CS(=O)(=O)NC1=C2N=C(C=C(O)C2=CC=C1)C(=O)NC1=CC=C(F)C=C1O
[H]OC(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C([H])=C2N1C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C2=C([H])N(N=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C1Br)C([H])=C([H])C1=C(C(Br)=C([H])C(Cl)=C1[H])[C@]2([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C([H])=[N+]([O-])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])N(C(=C2C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2C([H])([H])OC([H])([H])C([H])(F)F)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C(Cl)C(=C([H])C(Cl)=C1S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(SC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C(F)C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])=C([H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]OC1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C2=C3N=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])=C2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])SC([H])=N3)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@]2(OC([H])([H])C3=C2C([H])=C(C([H])=C3[H])C([H])([H])C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C#CC1=NC2=C(N=C([H])N2[C@]2([H])O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])[C@@]2([H])O[H])C(=N1)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(\C([H])=C(/[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N(C2=C1C(=NC([H])=N2)N([H])[H])[C@]1([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C2=C(OC3=C([H])C(=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=NC([H])=C2S1
[H]SC([H])([H])C([H])([H])[C@@]([H])(S[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])SC(=O)N([H])C1=O
[H]N(C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C2C([H])=NN1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)O[H])C([H])([H])P(=O)(O[H])O[H]
[H]N(C1=NC([H])([H])C2=C1C([H])([H])N(C(=O)N([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2(C([H])([H])[H])C([H])([H])[H])C1=NC(=NC(=N1)[N@@]1C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(Cl)=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])=C([H])C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Br)S1)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C2C(=NC3=C(C([H])=NN13)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
OC1=CC=CC(\C=C\C(=O)NC2=C(Cl)C=CC=C2)=C1
[H]N(C1=C([H])C([H])=C([H])C(Br)=C1[H])C1=C(C#N)C([H])=NC2=C([H])C3=C(OC([H])([H])C([H])([H])C([H])([H])O3)C([H])=C12
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C(S1)N(C([H])=C(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])[C@]2([H])C3=C(OC([H])([H])[C@@]2([H])C1([H])[H])C([H])=C([H])C(C#N)=C3[H]
OC(COC1=CC=CC=C1)CN1CCC(CC1)NC1=NC=NC2=C1C(=CS2)C1=CC=C(F)C=C1
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[H]N(C1=C2C([H])=NC(F)=C([H])C2=NC([H])=N1)C1=C([H])C([H])=C([H])C(Br)=C1[H]
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[H]N([H])C1=C(C([H])=C(C([H])=N1)C1=C([H])N(N=C1[H])C([H])([H])[H])C1=NC2=C(O1)C(=C([H])C([H])=C2[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=NC2=C(C([H])=N1)C([H])=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NN=C(N2[H])C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N=C(N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1
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[H]N([H])[C@]([H])(C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C2=C(ON=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(=N1)C1=C([H])N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(C([H])([H])C1=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C(=O)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2F)C2=C(C([H])=C([H])C([H])=C2[H])N(C1=O)C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]SC([H])([H])[C@]([H])(N([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N=C(N([H])C1=C([H])C([H])=C([H])C([H])=C1I)N([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N([H])C1=NC(C#CC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C#N)=C([H])S1
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[H]N(C(=O)N1C(=O)N(C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C(F)=C1[H]
[H]N([H])C1=C(SC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(F)(F)C(F)(F)F
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C(=O)C([H])([H])[H])C([H])=C1OC1=NC([H])=C(C([H])=C1Cl)C(F)(F)F)S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])=C([H])[H])[C@@]([H])(C2([H])[H])[C@@]1([H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC(=NC(=N1)N(C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])N1SC2=C([H])C([H])=C([H])C([H])=C2C1=O
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[H]N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N1N=C(C(=O)OC([H])([H])C(F)(F)F)C2=C([H])C([H])=C([H])C([H])=C12
[H]OC1=C([H])C([H])=C(C([H])=C1Br)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N1\C(S\C(=C(\[H])C2=C(N(C(=C2[H])C([H])([H])[H])C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1=O)=N\C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C([H])C(OC([H])([H])C([H])([H])F)=C(OC([H])([H])[H])C(=C1[H])C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1(N2C(=NC([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(OC([H])([H])C([H])=C([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]1(C#N)C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)[C@@]([H])(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
COC1=CC=C(C[C@H](N)C2=NC3=CC=C(C=C3C(=O)N2)C2=CNN=C2)C=C1
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]C1=C([H])C(=C([H])C([H])=C1Cl)S(=O)(=O)N1[C@@]([H])(C([H])([H])OC(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])OC([H])([H])[C@@]1([H])C1(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]SC1=NN2C(S1)=NN=C2C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]N([H])[C@]([H])(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
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[H]O[C@@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])N(C(=O)C2=C([H])C([H])=C([H])C(=C12)C([H])([H])[H])C([H])([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N1C([H])=C([H])C([H])=C1C1=C2C(=O)N([H])C3=C([H])C([H])=C(F)C(=C23)C(=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)N(C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C2=NC3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3C2=O)C2=C(N1[H])C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]N(C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H])[C@@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C(C([H])=C3[H])N2C([H])=NN=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)N([H])[C@@]1([H])C([H])([H])OC(O[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C1=C(Cl)C([H])=C([H])C(Cl)=C1[H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]N([H])C1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C(=O)N([H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)[C@@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC(=C1C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(N([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC([H])=C(C([H])=C1[H])N1C([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]2([H])C1([H])[H]
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[H]N(\C(=N/C#N)N1C([H])([H])C([H])([H])C(=C2C3=C(C([H])=C(Br)C([H])=N3)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=NC(=C([H])C(=N1)C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(O1)C([H])([H])[H]
[H]N1C2=C([H])C([H])=C3C4=C(C([H])=C([H])C([H])=C4[H])N(C3=C2C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)[C@]([H])(C([H])([H])N([H])[H])C([H])([H])C2=C(C([H])=C(O[H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N=C1[H])C1=NC(=C([H])S1)[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]2(C([H])=C([H])C3=C2C([H])=C([H])C([H])=C3[H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C([H])C(=NC([H])=N2)C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C1=C([H])C(F)=C(F)C([H])=C1F
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=C(N=NN2C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N(C1=C(C2=C(N([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C1=C(C#N)C([H])=NC([H])=C1\C([H])=C(/[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(N([H])C2=NC(=C([H])S2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=[N+]2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)=C1[H]
[H]N(C(=O)N([H])C1=C([H])C(C2=C([H])C([H])=NN2C([H])([H])[H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])[C@]2([H])C([H])([H])[C@@]1([H])[C@@]1([H])C(=O)N(C(=O)[C@@]21[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=NC([H])=C2Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C(=O)[C@@]([H])(N(C(=O)C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C(=O)O[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])=C([H])C(=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(\C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C1/C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N(C(=O)OC1(C([H])([H])C1([H])[H])[C@]1([H])N([C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=NN2C(=N1)C(O[H])=NC1=C([H])C(Cl)=C([H])C(Cl)=C21
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C(Cl)=C3[H])C([H])=C2C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(N1C(=O)C(C2=C1C(F)=C([H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
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[H]N(C(=O)C1=C([H])C2=C(N=C(S2)N([H])C2=NC([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=NC([H])=C(C([H])=C2C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=NC(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])=C(C([H])=N2)C2=C([H])C([H])=C3OC([H])([H])C([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
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[H]N([H])[C@@]1(C([H])([H])[H])C([H])([H])N(C2=C([H])C(=O)N(C(=O)N2C([H])([H])C2=C(C#N)C([H])=C([H])C(F)=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(SC([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
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[H]N([H])C(=N\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=N2)C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N3)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=NN=C(N3[H])C3=C([H])N=C(N([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C([H])N1[H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])N2C(=O)C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
NC1=NC(Cl)=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])N(C(=O)C2=C([H])C(=NC(=C2[H])C([H])([H])[H])C2=C([H])C([H])=C([H])S2)C([H])([H])[H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)[C@]([H])(C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C(F)=C(F)C(F)=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(OC2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])=C([H])C(=N1)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(OC([H])([H])[H])=NC(=C1[H])C1=C([H])C(C(=O)OC([H])([H])C([H])([H])[H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
COC1=C(O)C2=C3C(=C1)C(=O)OC1=C3C(=CC(OC)=C1OC)C(=O)O2
[H]C1=NC2=C(C([H])=NC3=C2C([H])=C([H])C(=C3[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C#CC([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)N(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)C1=C([H])C2=C(N=C(C([H])=C2OC([H])([H])C2=C([H])C3=C(C([H])=C2[H])C(=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C3=O)C2=NN([H])N=N2)C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=C2C(Cl)=C([H])C([H])=C([H])C2=C1[H])C1=C([H])N=C(C#N)C(O[C@@]2([H])C([H])([H])N([H])C([H])([H])C([H])([H])C2([H])[H])=N1
[H]N([H])C1=NC(=C([H])C(=N1)C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(N=C(N2C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C4N(N=C3C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N4C(=O)C2([H])[H])C([H])([H])[H])C([H])=N1
[H]C1=NN(C2=NC(SC([H])([H])[H])=NC(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C12)C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
CS(=O)(=O)C1(CCNCC1)C1=CC(=NC(=N1)C1=CC=CC2=C1C=CN2)N1CCOCC1
[H]OC1=C([H])C([H])=C(\C([H])=C2/SC(=O)N(C2=O)C([H])([H])C(=O)N([H])[H])C([H])=C1[H]
[H]C1=C([H])C(C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])=C(C#N)C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C([H])([H])C1(C([H])([H])S[C@@]([H])(C2=C([H])C(\C([H])=C(/[H])C3=NC4=C(S3)C([H])=C(OC([H])([H])[H])C([H])=C4[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C(F)=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(Br)O1)[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(OC1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])C([H])([H])OC([H])([H])C([H])([H])N1C2=NC3=C(N2C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=N[C@]([H])(N(C(=N1)N([H])[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C([H])([H])C1=NOC2=C([H])C([H])=C([H])C([H])=C12
[H]N(C#N)C(=N/C1=C([H])C([H])=C([H])N=C1[H])\N([H])C1=C([H])C([H])=C(C2=C([H])N=C([H])O2)C(OC([H])([H])[H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C2C([H])=C(N([H])C([H])([H])C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C([H])C2=N1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2([H])N(C1=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(S1)C(=O)C1=NC(=NC2=C1SC([H])=C2[H])C(F)(F)F
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)C([H])=C2[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC(=O)N([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C(=C2N=C(SC2=C1C([H])([H])C([H])([H])[H])N([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(Br)C(=C1[H])N1C2=C(N=C1C([H])([H])[H])C(=NC(=N2)C([H])([H])[H])N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])N1C(=NC2=C1C([H])=C([H])N=C2[H])C([H])([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N(C1=NOC2=C(C3=C([H])C4=C(C([H])=C3[H])C(C(=O)N4[H])(C([H])([H])[H])C([H])([H])[H])C(=C([H])C([H])=C12)C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])=O
[H]O[C@]1([H])C([H])([H])S[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])[C@]1([H])O[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])=C1[H]
[H]N([H])C(=O)C1=C(N([H])[H])C2=C(S1)N=C(C([H])=C2C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Br)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C2=C(N=C(N=C2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(\C(=C1/C(=O)N([H])C2=C([H])C(=C([H])C([H])=C12)C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C([H])C(=NC2=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])=C1[H]
[H]C1=C2N(C(=NC2=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])(F)F)C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C2N(C([H])=C(C(=O)C3([H])C(C([H])([H])[H])(C([H])([H])[H])C3(C([H])([H])[H])C([H])([H])[H])C2=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])N=C12
[H]N(C(=O)C([H])([H])[H])C1=NOC2=C(C3=C([H])C4=C(C([H])=C3[H])C(=NN=C4[H])N3C([H])([H])C([H])([H])OC([H])([H])[C@]3([H])C([H])([H])[H])C(=C([H])C([H])=C12)C([H])([H])[H]
[H]N([H])C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])[C@]12[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N(C1=C([H])C(OC([H])([H])C(F)(F)F)=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])C(F)(F)F
[H]N(C1=NC(=O)[C@]([H])(S1)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])N=C(SC2=C3C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C3=NC([H])=N2)S1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C(C2=C1N1C(=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]13[H])N(C2=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C3=C([H])C4=C(C([H])=C3[H])N(C(=O)C([H])([H])O4)C([H])([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])N=C3C(=N2)C2=C([H])C([H])=C([H])C(SC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)[C@@]2([H])N([H])C(=O)N([H])C(=O)C2([H])[H])C([H])=C1[H]
[H]N1[C@@]2([H])C3=C(N(C4=C([H])C([H])=C(C([H])=C34)S(=O)(=O)C3=C([H])C(=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N([H])C1=NC(=C(C(=C1C#N)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=C3C(=C([H])C([H])=C2[H])N(C([H])=C3C([H])([H])C([H])([H])C2=C([H])C([H])=C3OC([H])([H])C([H])([H])C3=C2[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C(F)C(F)=C(F)C(F)=C1F)C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C(N([H])C(=N/C([H])(C([H])([H])[H])C([H])([H])[H])\N([H])C#N)=C([H])C([H])=C1[H]
[H]N1C([H])=C(C(=O)N1C1=C([H])C(=NC([H])=N1)N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])S1)S(=O)(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=CC(NC(=O)NCCC(C2=CC=CC=C2)C2=CC=CC=C2)=CC=C1
[H]N(C1=NC([H])=C([H])C([H])=N1)C1=C([H])C2=C(C([H])=C1[H])N(C1=C2C2=C(C(=O)N([H])C2([H])[H])C2=C1C([H])([H])C([H])([H])C1=NN(C([H])=C21)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N(C1=NC([H])=NC(N([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C2[H])=C1[H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)N([H])[C@@]1([H])C(=O)N(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(N([H])C(=O)N([H])C([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=CC(\C=C2/CCC\C(=C/C3=CC=C(F)C=C3)C2=O)=CC(OC)=C1
[H]N(\N=C(/[H])[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O\N=C1\C(\N([H])C2=C\1C([H])=C([H])C([H])=C2[H])=C1\C(=O)N([H])C2=C([H])C(F)=C([H])C([H])=C12
[H]OC(=O)C(\[H])=C(\C(\[H])=C(/[H])C([H])([H])N(C1=C([H])C(=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])/C([H])([H])[H]
[H]N([H])C1=NN(C([H])=C1C1=C([H])C2=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C2([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C2N=C([H])N([H])C2=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC([H])=C(N2C([H])([H])C#CC([H])([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])[C@]1([H])C(=O)C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=S)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N2C([H])=C([H])C([H])=C2C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(Br)C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=NC([H])=C(Cl)N=C1C([H])([H])N([H])C(=S)N([H])C1=C([H])C([H])=C([H])C([H])=C1SC([H])([H])[H]
[H]N(C(=O)C1(N([H])C(=O)C2=C([H])C3=C(S2)C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C([H])N=C1[H])C1=NC([H])=C2N([H])N=C(C2=C1[H])C([H])([H])[H])C([H])([H])C1=C(C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
CCC1=NC=C2C(CCC3=CC=C(C=C3)C(F)(F)F)N(CCN12)[C@@H](C(=O)NC)C1=CC=CC=C1
[H]OC(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C([H])S1)C1=C([H])C([H])=C2OC([H])([H])C([H])([H])OC2=C1[H]
[H]N1C2=C(N=C1[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]1(OC([H])([H])C(N([H])[C@@]1([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]C1=C(C(C(=O)C2=NC(=NC(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C2C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(SC2=NC(=C3C(=C12)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(OC([H])([H])[H])C(C2=NC(Cl)=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=N2)C([H])([H])[H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C(ON=C1C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@]1([H])[C@@]([H])(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(O[C@@]2([H])OC(=C(C(=O)OC([H])([H])C([H])([H])[H])[S@](=O)[C@@]12[H])C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N([H])C1=NC2=NN(C(SC([H])([H])C([H])([H])C([H])([H])[H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])C(=O)OC([H])([H])[H])=C(C([H])=C1OC([H])([H])C([H])([H])C([H])([H])OC1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C3C(=C1[H])C1=C(O[H])C(O[H])=C([H])C([H])=C1C([H])([H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])[H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=N1
[H]N1C([H])=NC2=C(N=C(C([H])=C12)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C#N
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(N([H])C2=C([H])C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C3=O)=C1[H]
[H]N(C(=O)C1=C2C([H])=C([H])OC2=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])N(C(=O)C2=C(SC(=N2)C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C3=C1C([H])=C([H])C([H])=C3[H])C(=O)N([H])[H])C([H])([H])C1=C(C([H])=C(Cl)C([H])=C1[H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1Br)[C@@]([H])(O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H])C([H])([H])N([H])[H]
[H]C([H])=C([H])C([H])([H])OC(=O)C1=C2C(=NC1=O)C1=C3C2=C([H])C([H])=C([H])C3=C([H])C([H])=C1[H]
[H]N(C1=NC(N([H])C2=C([H])C([H])=C3N([H])C([H])=C([H])C3=C2[H])=C(C([H])=N1)C(F)(F)F)C1=C([H])C2=C(N([H])C([H])=C2[H])C([H])=C1[H]
COCCC1(CCCC1)C(=O)N[C@@H](CC1=CC=C(C=C1)C1=C(C)N(C)C(=O)N(C)C1=O)C(O)=O
[H]C1=C(OC([H])([H])[H])C2=C(C([H])=C1OC([H])([H])[H])C([H])([H])[C@]1([H])N(C2([H])[H])C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C12
[H]N([H])C1=C([H])C2=C(N=C(SC([H])([H])C3=C([H])C(F)=C([H])C([H])=C3[H])S2)C([H])=C1[H]
CC(C)CN1N=CN=C1C1=CC2=C(S1)C1=CC=C(C=C1OCC2)C(N)=O
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C(=O)N(C(=N2)C([H])([H])C([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C(C2=C(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C3=C([H])C(OC([H])([H])[H])=C([H])C(=C3N=C12)C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1(C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])C1=C([H])N(C2=C1C(F)=C([H])C([H])=C2C([H])([H])N1C([H])=NC([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C([H])=C([H])C2=C1N([H])C1=C2C2=C(C(=O)N(N([H])S(=O)(=O)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C2=O)C2=C1N(C1=C2C([H])=C([H])C([H])=C1O[H])[C@]1([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
CC1=CC=CC(=C1)C1=C(C=C(N1)C1=CC=NC=C1)C(N)=O
[H]OP(=O)(O[H])[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(C2=C([H])C([H])=NN2C([H])([H])[H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])[C@@]4([H])[C@]5([H])O[C@]5([H])C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]N1C(=NC2=C1N([H])C(=O)N(C2=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
BrC1=C2NC3=C(C=CC4=C3NC=C4C=O)C2=CC=C1
[H]N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1=O
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N([H])C2=NC([H])=C(C([H])=C12)C1=C([H])OC([H])=C1[H]
[H]N(C1=N[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C(C(=O)OC([H])([H])[H])=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NOC(=N2)C([H])([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C([H])C([H])=N1)C1=C([H])C2=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C2=O
[H]OC(=O)C(=N\O[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])\C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC1=C([H])C([H])=C2N(C([H])=C(C2=C1[H])C([H])([H])[H])N(C1=C([H])C([H])=NC([H])=C1F)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([C@]([H])(C(=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(Cl)C2=C1C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C2([H])[H]
CNC(=O)C1=NC=C(C=C1)[C@]1(O)CCN([C@H]1C)C1=CC(F)=C(C=C1)C#N
[H]N([H])C1=NC2=C([H])N(N=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]N1C2=C(C([H])=C([H])C(Cl)=C2[H])[C@]2(C1=O)[C@]([H])(N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@]2([H])C1=C([H])C(Cl)=C(F)C([H])=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1=NC(=C(N([H])C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(F)(F)F)[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])=C(C([H])=C2[H])N1C(=O)C([H])=C([H])C1=O
COC1=CC=CC=C1CNC1=NC(NC2CCCC2)=C(C=N1)C(=O)NCCNC(C)=O
[H]C([H])([H])[C@]1([H])SC(=O)[C@]2([H])N(C1=O)C([H])([H])SC2([H])[H]
[H]N(C(=O)OC1(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])N([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(\C([H])=N\C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=NN=C1Cl)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C(=O)O[H])[C@@]([H])(C2=C(Cl)C([H])=C([H])C([H])=C2[H])C(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])=C(N1C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C2N(C(SC([H])([H])C3=C(Cl)C([H])=C(C#N)C([H])=C3[H])=NC2=C1[H])C([H])([H])[H]
[H]N([H])C1=C(SC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C(C([H])=C([H])[H])=C1[H]
[H]S\C(=N\C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=C(C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])[C@]1([H])C([H])([H])OC2=C([H])C([H])=C([H])C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C2C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(N([H])C(=S)N([H])N([H])C2=C3C([H])=C([H])C([H])=C([H])C3=NC2=O)=C1[H]
[H]OC(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C2([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C1C([H])=C1C([H])=C([H])C([H])=C([H])C1=C2[H])C([H])([H])C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=C(C2=C([H])SC(=N2)C([H])([H])[H])C1=O)C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(C(N([H])C2=NC([H])=C(S2)C2=C([H])C([H])=C([H])N=C2[H])=C1[H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C1C(=C([H])C(=C2[H])S(=O)(=O)C1=C([H])C([H])=C2N(C3=C(C2=C1[H])[C@@]1([H])N([H])[C@]([H])(C([H])([H])C1([H])[H])C3([H])[H])C([H])([H])[H])C(F)(F)F
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C#N)C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(C([H])=C(C([H])=N1)C1=C([H])N(N=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=NC2=C(O1)C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C2[H]
[H]ON([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C2=C(C3=C(N2[H])C([H])=C([H])C(Br)=C3[H])C1([H])[H]
[H]C#CC([H])([H])OC1=NC(=NC(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1OC1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])N=C([H])C([H])=N1
[H]O[C@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])[C@]4([H])[C@]5(C([H])([H])[C@@]35C(=O)C([H])([H])[C@]2(C([H])([H])[H])[C@@]1([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])N=C(SC([H])([H])[C@@]41C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
COC1=CC(=CC=C1)C(=O)N1CCN(CC2=CC=C(C=C2)C2=NN=C3N2C2=CC=CN=C2NC2=C3C=CC=C2)CC1
[H]N1O\C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])=C1/C([H])=C([H])C([H])=C([H])C1=O
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C2C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C#CC([H])([H])N(C(=O)[C@@]1(C2=C([H])C([H])=C3OC([H])([H])C([H])([H])OC3=C2[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])[H])C([H])([H])C#C[H]
[H]N=C(N([H])[H])N([H])C1=NC([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]O[C@@]([H])(C1=C(SC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)P(=O)(O[H])O[H]
[H]OC(=O)C([H])([H])C([H])([H])N(C(=O)N([H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]C([H])=C([H])C([H])([H])N1C(=O)N(C2=C(N([H])C(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])C4=C(C5=C(N4[H])[C@]4([H])OC6=C(O[H])C([H])=C([H])C7=C6[C@@]44C([H])([H])C([H])([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])[C@]([H])(C7([H])[H])[C@]4(O[H])C5([H])[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C2S[C@@]([H])(C([H])([H])[H])C([H])([H])C3=C2C(N1[H])=C([H])C([H])=C3OC([H])([H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(=C(/[H])C1=C(C([H])=C([H])C(OC([H])([H])C2=C([H])SC([H])=C2[H])=C1[H])[N+]([O-])=O)\C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])C1=NN=NN1C1=C(Cl)C(Cl)=C(F)C([H])=C1[H]
[H]N([H])C(=NOC([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C(=O)N(C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])N([H])[H]
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[H]N(C(=O)OC([H])([H])[H])C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC([H])([H])[H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@@]([H])(O[H])[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(N=C2N1[H])C1=C(N([H])N=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
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[H]C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C(=O)C(=C(C2=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1C([H])=C([H])C(Cl)=C2[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C([H])=C([H])C2=C1C([H])=C([H])N=C2[H]
[H]N(C1=NN=NN1C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]OC1=NC2=NC([H])=C([H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C(Cl)C([H])=C([H])C(N([H])\N=C2\C3=C([H])C([H])=C([H])C([H])=C3O[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])=C1[H]
ClC1=CC2=C(C=C1)C(=O)N([C@@H](CC1CCCCC1)C(=O)NC1=NC=CS1)C(=O)N2
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[H]OC(=O)C1=C([H])C(=C([H])C(N([H])C(=O)C([H])([H])[H])=C1[H])N1C(=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C(I)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C(=O)OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])=NC3=C([H])C([H])=C(C([H])=C3C2=O)N(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])C1=NN=NN1C([H])([H])[H]
[H]C1=C([H])C(Cl)=C2N=C(N(C2=C1[H])C1=C([H])C(OC2=C([H])C(F)=C([H])C(=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C([H])C(=N1)C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N1C(=O)N([H])C(=O)C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[18F])C([H])([H])C2([H])[H])(C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1N=C(N(\N=C(/[H])C2=C([H])C([H])=NC([H])=C2[H])C1=S)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])C([H])=C2C(=NN([H])C2=C1[H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=NC2=C1C1=N[C@@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])N1C(=O)N2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C([H])C(=C2C(=O)C3=C([H])C([H])=C([H])C([H])=C3C2=O)C2=C([H])C([H])=C([H])C([H])=C12
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N(C(=O)C([H])([H])N(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C(SC2=C1C(=O)N(C(=O)N2C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
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[H]OC1=C([H])C([H])=C2C3=C1OC1([H])C33C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])(C2([H])[H])C32C([H])=C([H])C1(OC([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])(C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
NCCCCC(NC(=O)CN(CCC1=CC=CC=C1)C(=O)CCC1=CC=CC=C1)B(O)O
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[H]N(C1=C(C(=O)C([H])([H])[H])C(=C([H])C([H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=NC2=C(N=NN2C2=C1SC([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C2C([H])=C([H])N(C2=N1)C1=C([H])C([H])=C([H])C([H])=N1)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])=C(C2=C([H])C3=C(O2)C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]ON(C(=O)N([H])[H])[C@]([H])(C1=C([H])C([H])=C(O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C(=C1[H])C1=NN=C(O1)C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])N(C2=C([H])C(O[H])=C([H])C([H])=C2C1([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N2N=C(N=C2C(=N1)N([H])[H])C1=C([H])C([H])=C([H])O1
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1(C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])N(C([H])=N1)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])N(C(=O)C2=C([H])C3=C(OC4=C(C([H])=C([H])C([H])=C4[H])[C@]3([H])C(=O)N([H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])/C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C\4([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C([H])C(Cl)=C(OC([H])([H])[H])C(Cl)=C2[H])C([H])([H])C2(C([H])([H])C2([H])[H])C1([H])[H]
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[H]N([H])C(=O)[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]N([H])C1=C2N=C([H])N([H])C2=C(C([H])=C1[H])C(=O)N([H])[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N(C(=O)N1C(=O)[C@@]([H])(C([H])([H])[H])[C@@]2([H])N(C(=O)[C@@]3([H])N(C([H])([H])C([H])([H])C3([H])[H])S(=O)(=O)C3=C4C([H])=C([H])C([H])=C(N(C([H])([H])[H])C([H])([H])[H])C4=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]12[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CN1C(\C=C\C2=CC=C3OCOC3=C2)=CC2=C1C(=O)N(C)C(=O)N2C
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=NO[N+]([O-])=C1C(=O)N([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)[C@@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C3C(Cl)=C([H])C([H])=C([H])C3=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C1=C(C([H])=NO1)C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])=C1[H])C([H])([H])[H])C2([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C(O[H])C(=O)C2=C([H])C(=C([H])C(N3C(=O)C([H])([H])C([H])([H])C3([H])[H])=C2O1)C([H])([H])[H]
[H]N([H])C(=O)[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@]([H])(N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])N(C4=C(F)C([H])=C(F)C([H])=C4F)S1(=O)=O)[C@]([H])(C3([H])[H])C2([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1N=C(C#N)C(=O)N(C1=O)C([H])([H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(OC([H])([H])C(=O)N2C([H])([H])C([H])([H])C3(C([H])([H])N(C([H])([H])C4=C([H])C([H])=C(C([H])=C4[H])C4=NN=C(O4)C([H])([H])[H])C3([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N([H])C1=C(I)C([H])=C(C([H])=C1Cl)S(=O)(=O)N([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1C(=O)N2[C@@]([H])(C1=O)[C@]1([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])C(F)(F)F
[H]\C(=C(\[H])C1=C([H])C([H])=C(SC2=C(C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])[N+]([O-])=O)C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C2=C(OC([H])=C([H])C([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C2=C(OC(=N2)C2=C([H])C([H])=NC([H])=C2[H])C([H])=C1[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C2(OC3=C(Cl)C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=C23)C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N(OC([H])([H])[H])C(=O)C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)N([H])C([H])([H])C([H])([H])[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C2C([H])=C([H])C(=C([H])C2=NC([H])=N1)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C2=NC3=C(N2[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N1[C@@]2([H])C3=C(N(C4=C(F)C([H])=C(C([H])=C34)S(=O)(=O)C3=C([H])SC4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]C1=C(C(=NN1C([H])([H])C1=C([H])C([H])=C([H])C(C#N)=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C2=C([H])C([H])=C([H])N=C2C([H])=C1[H]
[H]N([H])C(C(=O)N([H])[C@@]1([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C(=O)N([H])C([H])([H])[C@@]1([H])C([H])([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=C([H])C2=NC([H])=C([H])C([H])=C12)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C(C2=C(N([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C(C#N)C([H])=NC2=C1C([H])=C(S2)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C2=NC([H])=N1)C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O
[H]OC(=O)C(=O)[C@]1([H])N(C([H])([H])C2=C(C([H])=C([H])C(=C2[H])[N+]([O-])=O)C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=C2C(=NC3=C1C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C1=C2C(=NC3=C(C(=NN13)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@@]1([H])N=C(N(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
CC1=CC=C(C=C1)C(SCCN)(C1=CC=CC=C1)C1=CC=CC(=C1)C#N
[H]N(C(=O)N1C([H])([H])C([H])([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])C([H])([H])N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])[C@]([H])(N2C(=NC4=C2C([H])=C([H])C([H])=C4[H])C([H])([H])[H])C3([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC1=C(C([H])=C(OC2=NC(OC3=C([H])C([H])=C([H])C(=C3[H])C(=N[H])N([H])[H])=C(F)C(=C2F)C([H])([H])[H])C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
CN(C)C(=O)C(CN1CCC2(CC1)OCCC1=C2SC=C1)CC1=CC=CC=C1
[H]O[C@]([H])(C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C2=C(N=C1[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C2=NC3=C(C(F)=C([H])C([H])=C3N2[H])C([H])([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
COCC(=O)NC1=NN=C(S1)C1=CC=C(C=C1)C(O)=O
CSC[C@@H]1CC[C@@H](CO[C@H]2CC[C@@H](CC2)C(O)=O)N1C(=O)CC1=C(F)C2=C(C=C1)N=C(NC1=CC(F)=CC=C1C)O2
[H]N1C(=O)N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N3C([H])=C(C4=C([H])C([H])=C([H])C([H])=C34)C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=NC(N([H])C([H])([H])[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=C2C(OC(=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=NC([H])=N1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])N=C1[H]
CCC(C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)C(C)N)C(C)C)C(C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NC(C)(C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O
[H]N(N([H])C(=O)C([H])([H])SC1=NN=C(N1N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N(C(=O)C1=C(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])[C@@]2([H])N([H])[C@]1([H])C([H])([H])N(C(=O)C([H])([H])[H])C2([H])[H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)[C@@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(N=C([H])N=C2C([H])=C1OC([H])([H])C([H])([H])OC([H])([H])[H])N([H])C1=C2OC([H])([H])OC2=C([H])C([H])=C1Cl
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(S2)[C@]([H])(C2=C([H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])C([H])=C([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]OC(=O)[C@@]1([H])N(\C([H])=C2/C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@]3(C2=C(O[H])C(=O)C2=C3[C@]([H])(OC(=O)C([H])([H])[H])C([H])([H])[C@@]3(C(=O)C([H])([H])C([H])([H])[C@@]23[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC([H])([H])C1=C([H])N(N=C1C(F)(F)F)C([H])([H])C1=C([H])C2=C(C([H])=C1[H])[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C2([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1F)[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C(=N2)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C(OC2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC2=NC([H])=C(Br)C([H])=N2)=N1)C([H])([H])C([H])([H])N([H])C([H])([H])[H]
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[H]C1=C([H])C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])N([C@]([H])(C4=C([H])C([H])=C(C([H])=C4[H])S(=O)(=O)C4=C([H])C([H])=C(OC([H])([H])[H])C5=C4OC([H])([H])O5)C([H])([H])[H])[C@]([H])(C([H])([H])[H])C3([H])[H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1N=C(N=C1SC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(F)C(Cl)=C1[H])C1=C2C([H])=C(N([H])C([H])([H])C3=C([H])N([H])C([H])=N3)C([H])=C(Br)C2=NC([H])=C1C#N
[H]OC(=O)C([H])([H])[C@]([H])(N1C(=O)N(C2=C(C([H])=NC([H])=C2[H])C1=O)C([H])([H])C1=C([H])N(C2=C1C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]OC1=C([H])C(O[H])=C(C([H])=C1Cl)C1=C(C(=NO1)C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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[H]C1=NC([H])=C(N=C1Cl)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)[C@@]3([H])[C@@]([H])(C2=O)[C@@]2([H])C([H])=C([H])[C@]3([H])[C@@]3([H])C([H])([H])C([H])([H])[C@@]23[H])C([H])([H])C1([H])[H]
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[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C2=C(C3=NN=C(N3C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C1=NN(C2=C1C([H])([H])C1=C2C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=N\C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])\N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
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[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2=O)C([H])([H])C#CC1=C([H])C2=C(C([H])=C1[H])N1C(=NN=C1C([H])([H])N=C2C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H]
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[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C(=O)N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H]
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[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C([H])=C3C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N([H])C1=O
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[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1OC1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])=C(C(=O)N2C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
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[H]N([H])C1=C(Br)C(=NC2=C(C([H])=NN12)C1=C([H])N(N=C1[H])C([H])([H])[H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])=C(C2=C1C([H])=C1OC([H])([H])C([H])([H])N(C1=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]N=C(N([H])[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[C@]([H])(N([H])C(=O)[C@@]2([H])N3C(=O)C([H])([H])N(C(=O)C([H])([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@]3([H])C([H])([H])C2([H])[H])C(=O)C2=NC3=C(S2)C([H])=C([H])C([H])=C3[H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N2N=C([H])C(=C2[H])C(=O)N([H])C([H])([H])C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
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[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C2=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H]
[H]N(C(=O)N1C(=O)C2=C([H])C([H])=C(F)C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@](C1=C([H])N(N=N1)C([H])([H])C1=C([H])C([H])=C2C(SC(C(=O)N([H])[H])=C2C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H])(C([H])([H])C([H])([H])[H])C(F)(F)F
[H]OC(=O)C1=C([H])C([H])=C(N([H])C2=NC(N([H])C3=C(C([H])=C([H])C([H])=C3[H])C(F)(F)F)=C([H])C([H])=N2)C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])C([H])([H])[C@@](O[H])(C([H])([H])C4=C([H])C([H])=C(C([H])=C4[H])C4=C([H])C([H])=C([H])C([H])=C4[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
[H]N([H])C(=O)C1=C([H])C(=C([H])C2=C1N([H])C([H])=C2[H])C1=C(OC([H])([H])[H])C([H])=C([H])N=C1[H]
[H]N(C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1(OC([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C(=C([H])S1)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(F)C(=C2N=C1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])[C@@]3([H])C2([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2N([H])C([H])=C([H])C2=C1C([H])([H])[H])C1=C(C#N)C([H])=NC([H])=C1C1=C([H])N=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C2([H])[H]
[H]N(C1=NC(=C([H])S1)C1=C(N=C2N=C([H])C([H])=C([H])N12)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C#CC([H])([H])OC1=C(C([H])=C(Cl)C(N([H])[H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C(N=C(O1)[C@@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[N+]([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC(=O)C([H])([H])N1C(=O)[C@@]([H])(C2=C(C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])C1=C(ON=C1C([H])([H])C(\[H])=C(/[H])C([H])([H])[H])N([H])[H])(C(F)(F)F)C(F)(F)F
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[H]OC1=C([H])C(=C([H])C([H])=N1)C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])SC2=NC3=C([H])C([H])=C([H])C([H])=C3O2)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=NC2=C(C([H])=NN12)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(Cl)C([H])=C(N([H])C2=C(C(=O)N([H])C2=O)C2=C([H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C([H])=C1Cl
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[H]OC([H])([H])C([H])([H])N1OC(=O)C2=C1N(C1=C(C([H])=C(F)C(Cl)=C1[H])C2=O)C([H])([H])C([H])([H])[H]
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[H]O[C@@](C([H])([H])N1C([H])=C([H])C(=O)C2=C1C([H])=C([H])C([H])=N2)(C([H])([H])C(C1=C(OC([H])([H])[H])C([H])=C([H])C(F)=C1[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(C#N)=C([H])C(=C2O1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC(=C([H])C([H])=N2)C(F)(F)F)C([H])([H])C1([H])[H]
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[H]N1C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N
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[H]N(C(=O)C1=NC2=C(S1)N=C(N([H])C([H])([H])[H])C1=C2N(C([H])=N1)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C2=C(N([H])N=C2[H])C([H])=C1[H]
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[H]N([H])C(=O)C1=C(N([H])C(=O)N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C(C#N)(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])[C@@]1([H])C1=C(F)C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=O
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC(=NC(=N1)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])[C@@]([H])(N([H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C(=C1C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]OC(=O)[C@]([H])(OC1=C(C([H])=C(C([H])=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C2C([H])=C([H])C([H])=C3C2=NN1C([H])([H])C([H])([H])[N@]1C([H])([H])C([H])([H])[C@]([H])(OC2=C4N=C3C(O[H])=NC4=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]OC(=O)C1=C([H])C([H])=C([H])C(=N1)C1=NOC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2[C@]([H])(N(C(=O)OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C3([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)C1(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C2=NC3=C(C([H])=C([H])C([H])=C3[H])N(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C2=C([H])\C1=N/C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])[H])[C@@]1([H])C2=NN(C(=C2OC([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=C(C2=C(N=C([H])N=C12)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])O1)C(=O)N(C1=C(Cl)N=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C3=C(Cl)C([H])=NC(=C3[H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C21)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C(=NN1C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
CC(C)OC1=CC=C(C=C1C(F)(F)F)C1=NC2=C(O1)N=CC(CCCCCC(O)=O)=C2
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(=C2[H])[N+]([O-])=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)N2C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[C@@]2([H])C1=O
[H]N=C(N([H])[H])C1=C([H])C(=C(SC([H])([H])[H])S1)C1=NC(=C([H])S1)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
CC1=C(Cl)C=CC=C1C(=O)N1CCC[C@@H](C1)C1=NC(=NO1)C1=CC=C(F)C=C1
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@]11C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
OC1=CC(Cl)=C(C=C1)C1=CC=C(S1)C1=CC=C(O)C=C1Cl
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(\C([H])=C(\[H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]