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[H]C1=C([H])N2C(=C1[H])[C@]([H])(N(C(=O)C([H])([H])N(C(=O)[C@]([H])(Cl)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C2C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]N1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=C([H])[H])C1=C([H])C2=C(C([H])=C1O[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1(C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N(C(=O)N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC(=O)C([H])([H])[H])=C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])Br)C([H])=C1[H]
[H]OC1=C2O[C@@]3([H])C(=O)C([H])([H])C([H])([H])[C@@]4(N([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])C5=C([H])C([H])=C(Cl)C([H])=C5[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]OC(C1=C([H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])C3(O[H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C([H])C([H])=C2C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C2C([H])=C([H])C([H])=NN2N=C1[H])C([H])([H])C(F)(F)F
[H]O[C@@]([H])(C([H])([H])[C@]([H])(O[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])N1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2[C@]([H])(C1=O)C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@]([H])(C1=NN2C([H])=C([H])C(Cl)=C2C(=O)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C3=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=NN=C(N2C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C2C(N([H])N=C2C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])N(C2=C([H])C([H])=C([H])C(OC3=C(Cl)C([H])=C(Cl)C([H])=C3[H])=C12)C([H])([H])[H])S(=O)(=O)C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]O[C@@]1([H])C([H])([H])[C@]([H])(O[C@]1([H])C([H])([H])OP(=O)(O[H])O[H])N1C([H])=C(C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])C1=O
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])SSC([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=NC(O[C@]2([H])C([H])([H])C3([H])N([C@@]([H])(C([H])([H])C3([H])[H])C2([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1F
[H]OC(=O)C([H])([H])OC1=C2C(C(=O)C(=O)N([H])[H])=C(N(C2=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C3=NOC(=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=C([H])S2)C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
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[H]N(C(=O)C([H])([H])[C@]1([H])N(C2=C([H])C([H])=NC(=N2)N2C([H])=NC([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)[C@]1([H])N2C(=O)[C@]([H])(OC(=O)C([H])([H])[H])[C@]2([H])[S@](=O)C1(C([H])([H])[H])C([H])([H])[H]
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[H]N(C1=C2C([H])=NN(C2=NC(SC([H])([H])C([H])([H])C([H])([H])[H])=N1)C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=NOC(=C1[H])C1=C([H])C([H])=C(Cl)S1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(O[H])C(=C(C([H])=C2C(C(=O)N([H])[C@@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])=C1O[H])C([H])([H])[H])C1=C(O[H])C2=C([H])C(O[H])=C(O[H])C(C(=O)N([H])[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])[H])=C2C([H])=C1C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2N=C(N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(=S)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C(OC([H])([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1N=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2C([H])=C([H])C3=C([H])C([H])=NC([H])=C3C2=C1[H]
[H]ON([H])C(=O)C([H])([H])OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C(SC([H])([H])[H])N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]N(C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C(Cl)S1
[H]C([H])=C1C([H])([H])C([H])([H])[C@@]2([H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])=C([H])O[C@]3([H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@]1([H])C([H])([H])C1=C(OC([H])([H])[H])OC(=C(C1=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N2C(=C1[H])C(OC(=O)N(C([H])([H])[H])C([H])([H])[H])=C(OC1=C(Cl)C([H])=C([H])C([H])=C21)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1(O[H])C2=C(O[C@@]([H])(C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C(F)=C2[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=O)S2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC2=C(Cl)C([H])=C(C([H])=C12)C(F)(F)F)C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(\C(=N/S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)N1N=C([H])[C@@]([H])(C([H])([H])C([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N(N=C1[N+]([O-])=O)C(=O)C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C(OC2=C1C([H])=C1C([H])=C(OC([H])([H])[H])C([H])=C([H])C1=N2)C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C(C(=O)OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)(C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
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[H]C([H])=C([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])=C([H])[H])C([H])([H])C1([H])[H]
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COC1=CC2=C(C=C1)N(C(=N2)C(F)F)C1=NC(=NC(=N1)N1CCOCC1)N1CCOCC1
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[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])N(C(=N2)C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C(C#CC3=C([H])C([H])=C([H])C([H])=C3[H])=C(C([H])=C2N=C(C2=C([H])C([H])=C([H])C(C#N)=C2[H])C([H])([H])C1=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])C2=C3N=C([H])N([H])C3=NC(=N2)N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C2C([H])=C(C(=NC2=N1)N([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N1C(=NC2=C1N(C(=S)N(C2=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])O1
[H]N1C(=O)N([H])[C@]2(C1=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1S(=O)(=O)C([H])([H])C2([H])[H]
[H]N(C1=C([H])C(Cl)=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]O[C@@](C([H])([H])N([H])C(=O)C1=C(N([H])[H])N(N=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]C1=C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=C([H])C(Cl)=C(N=C2C(=C1[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])[H]
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[H]N(C(=O)[C@]([H])(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C(=O)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])OC([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])C2=C3ON=C(C3=C([H])C([H])=C12)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(N([H])C(C(=O)C2=C(F)C([H])=C([H])C([H])=C2F)=C1N([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C(S1)C1=NN(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C2=C(OC([H])=C2[H])C([H])=C1[H]
[H]OC([H])([H])C1=C([H])[C@]2([H])[C@]3([H])[C@](OC(=O)C([H])([H])[H])(C([H])([H])[C@]([H])(C([H])([H])[H])[C@]2(O[H])[C@@]2([H])C([H])=C(C(=O)[C@@]2(O[H])C1([H])[H])C([H])([H])[H])C3(C([H])([H])[H])C([H])([H])[H]
[H]\C(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])=C1\C([H])([H])N2[C@]3([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C3([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC(=N1)N([H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])S1
[H]N1C2=C([H])C([H])=C(F)C([H])=C2C2=C1C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]2([H])C([H])([H])C1([H])[H]
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[H]OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C(=C2[H])C2=C([H])C([H])=C(SC3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
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[H]OC(=O)[C@]1([H])N(C(=O)C([H])([H])[C@]([H])(SC(=O)C([H])([H])[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])[C@@]([H])(OC([H])([H])[H])C([H])([H])OC(=O)N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N(C(=O)C([H])([H])[C@]1([H])N(C([H])([H])C(N([H])C1=O)(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N1C([H])=C([H])C2=C3N(C([H])=NC3=C([H])N=C12)C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C#N)C([H])([H])C1([H])[H]
[H]N1C(SC([H])([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3O2)=NC([H])=C([H])C1=O
[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)OC([H])([H])[H])P(=O)(OC1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H])OC1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N([H])C(=O)N([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C([H])C(=C([H])C([H])=C2N=C1C([H])([H])C([H])([H])C([H])([H])[H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]OC([H])([H])[C@@]1([H])N(C(=O)C([H])([H])C(N([H])C([H])([H])C(=O)N2C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]2([H])C#N)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C1=NC([H])=C(SC([H])([H])C2=NC([H])=C(O2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S1)C1=C([H])C([H])=C([H])C([H])=N1
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[H]O[C@]([H])(C([H])([H])N([H])[C@]1(C2=C([H])C([H])=C([H])C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(O[H])C([H])([H])C1([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N([H])[C@]([H])(C1=NN=C(O1)SC([H])([H])C(=O)N([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
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[H]OC1=C([H])C(F)=C(C([H])=C1[H])C1=NC(=C([H])C([H])=C1[H])C(=O)C([H])([H])C1=C(C([H])=C([H])N=C1[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])=C1[H]
[H]O[C@](C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C(N([H])[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
CC(C)(C)OC(=O)N[C@@H]1CCN(C1)C(=O)O[C@H]1C2CC3CC1C[C@](C3)(C2)C#N
[H]N(C(=O)N1C([H])([H])[C@]([H])(N([H])[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H])C1=NC2=C(S1)C1=C(SC(=N1)C([H])([H])[H])C([H])=C2[H]
[H]N(C1=C([H])C([H])=C(C2=C([H])C(=NN12)C([H])([H])C([H])([H])[H])C1=NN([H])C(=O)C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C#N)C(=N\C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])\N1C([H])([H])C([H])([H])C(=C2C3=C(C([H])=C(Br)C([H])=N3)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])N(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])N([H])[C@]1([H])C([H])([H])C2([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(Cl)C([H])=C2C(=C1C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(N([H])C(=N[H])N([H])[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N1C2=C(C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])N=C1[H]
[H]N(C1=C([H])C([H])=[N+](C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[N+]1=C([H])C([H])=C(N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N1\C(S\C(=C(/[H])C2=C([H])C([H])=C(OC(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C(OC([H])([H])[H])=C2[H])C1=O)=N\C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN=NN1[H])C([H])([H])C([H])([H])C([H])([H])[H])C(O[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N(C(=O)O[C@]([H])(C([H])([H])[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C3C(=O)N([H])C([H])([H])C3=C3C(N([H])C4=C3C([H])=C([H])C([H])=C4[H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])[C@]([H])(N([H])C(=O)C4=C([H])C([H])=NC([H])=C4Br)C([H])([H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])N(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]OC1=C([H])C(O[H])=C(C([H])=C1[H])[C@@]1([H])OC2=C(C(OC([H])([H])[H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])O[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1N1C([H])=C([H])C2=C1N=C(N=C2[H])N([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H]
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COC1=CC2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=CC=NC(SC)=N3)C2=O)C=C1
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[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2C([H])([H])C([H])([H])C1([H])[H]
BrC1=CC=C(C=C1)C1=NN(C(C1)C1=CC2=CC=CC=C2C=C1)C1=CC=CC=C1
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=NN([H])C2=C1C([H])([H])N(C(=O)O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C2N([H])[C@]3([H])C([H])([H])[N@](C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C3=C(C4=C(N3C(C([H])=C1[H])=C2[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C4=O)C([H])([H])[H]
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[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C#N)C([H])=C1C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C(=O)N(C2=C([H])C([H])=C(Cl)C([H])=C12)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])C(=O)N2C3=C(SC4=C2C([H])=C([H])C([H])=C4[H])C([H])=C([H])C([H])=C13)C1=C(F)C([H])=C([H])C([H])=C1F
CCC1=NN2C(C=CC=C2C2=C(C)C=C(C)C=C2OC)=C1N(CC1CC1)CC1CCOC1
[H]N(\N=C(\[H])C1=C(C([H])=C([H])S1)C([H])([H])[H])C1=C(Cl)C(=O)N([H])N=C1[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C(=N1)N([H])[C@@]1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(=N1)C([H])=C([H])C([H])=C2C([H])([H])N([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C#N
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]
FC(F)(F)C1=CC(NS(=O)(=O)C2=CC=C(Cl)C=C2Cl)=CC=C1OC1=CC(Cl)=CN=C1
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
CC(C)NC1=C(N=NC2=C1C=CC(=C2)C1=CSN=C1)C(N)=O
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1Br)C([H])([H])C1=C([H])N(C(=O)S1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC2=C(OC([H])([H])C([H])([H])N([H])C([H])([H])C3=C([H])OC([H])=C3[H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N1C(C([H])=C(C2=C([H])C3=C(C([H])=C([H])C(=O)N3C3=C(Cl)C([H])=C([H])C([H])=C3Cl)C(=C2[H])C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=N/N1C([H])=NN=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
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COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC(=C1)N(=O)=O)C(=O)OC1CCCN(CC2=CC=CC=C2)C1
[H]OC1(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])SC1=NN=NN1C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C1=C(N=C(SC([H])([H])[H])N=C1SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C1=NC(N([H])C2=C([H])C([H])=C([H])C([H])=C2C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(Cl)C([H])=N1)C1=C([H])C([H])=C2N(C(=O)C([H])([H])C([H])([H])C([H])([H])C2=C1[H])C([H])([H])[H]
[H]N([H])C(=O)O[C@]([H])(C([H])([H])[H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C(C#N)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(OC2=C(C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@]([H])(O[C@]([H])(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C(C(=NC(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])N([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])OC1=C([H])C([H])=C(Br)C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(F)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NOC2=C1C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C1=O
[H]C1=C([H])C(=C([H])C([H])=C1F)[C@]([H])(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=NN=NN1C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])N=C23)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C([H])=C(Br)C([H])=C([H])C2=N1)C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N(N=C1C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C(=O)N([H])C([H])([H])C1=O)C([H])([H])O[H]
[H]N1C(=NC2=C([H])C(Cl)=C([H])C([H])=C12)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C([H])N=C2[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2C(=C1[H])N(C([H])=C2C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
COc1ccc2ccc(cc2c1OCC(N)=O)C(N)=N
[H]N(C1=NC([H])=C([H])N=C1C#N)C([H])([H])C1=C([H])C2=C(OC(=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]N(C(=O)C1=C(N([H])C([H])([H])C2=NC([H])([H])C([H])([H])N2[H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]12C([H])([H])C([H])([H])[C@@](C3=C([H])C([H])=C(C([H])=C3[H])C3=NC(C(=O)N([H])[H])=C(N=C3C([H])([H])[H])C([H])([H])[H])(C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C2=NOC(=C2C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C1([H])[H]
[H]C1=C([H])C2=C(S1)C(=NC1=C(N=NN21)S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H][C@@]12C[C@H](OC(=O)C3=CC=C(C=C3)N=[N+]=[N-])[C@@]3(C)OC4=C([C@H](O)[C@]3([H])[C@@]1(C)CC[C@H](OC(C)=O)[C@@]2(C)COC(C)=O)C(=O)OC(=C4)C1=CN=CC=C1
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C(\[H])=C(/C([H])([H])[H])[C@@]2([H])OC(=O)[C@@]3([H])N(C(=O)C(=O)[C@@]4(O[H])O[C@@]([H])([C@@]([H])(OC([H])([H])[H])C([H])([H])[C@]4([H])C([H])([H])[H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])\C(=C([H])\[C@]([H])(C(=O)C([H])([H])[C@]([H])(O[H])[C@@]2([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])C1=C([H])C([H])=C([H])S1
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C(N([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])=C2[H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])C(=O)N1C([H])([H])C([H])([H])C(=C2C3=NC([H])=C(Br)C([H])=C3C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C(N=C([H])N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C([H])([H])C1=C(N=C(O1)C1=C2C([H])=C([H])C(=NC2=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C(=O)N1C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2N=C(C3=C([H])C(N([H])C(=O)N([H])C4=C([H])C([H])=C([H])C(=C4[H])C(F)(F)F)=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N([H])C2=NC([H])=N1
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])[C@@]6([H])O[C@]([H])(C([H])([H])C6([H])[H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H]
[H]N([H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@]2([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=NN(\C(S1)=N/S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C([H])C(Cl)=C([H])N=C1N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]N([H])C([H])([H])[C@@]1([H])O[C@]([H])(C([H])([H])C([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C2N=C(N(C2=C1[H])C1=C([H])C(OC2=C([H])C([H])=C([H])C(=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])C3=C(N=C(N([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])N3[H])C([H])=C12
[H]N(C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H])C([H])([H])C([H])([H])N1N=C(C(Cl)=C1[H])C([H])([H])[H]
[H]N(C(=O)C(N([H])C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=NC([H])=C1C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2N([H])C1=O
[H]N1C([H])([H])C([H])([H])C([H])(N2C([H])=NC(=C2C2=C([H])C([H])=NC(OC3=C([H])C([H])=C([H])C([H])=C3[H])=N2)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(N2C(Cl)=C(Cl)C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C2C([H])=C([H])C([H])=C([H])C2=NN1C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(C#N)C(OC2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])=C1[H]
[H]O[C@]1(C#CC([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C#N)N1C([H])([H])[H]
[H]OC(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(P(=O)(O[H])O[H])P(=O)(O[H])O[H]
[H]OC1=C2C(OC(C([H])([H])[H])(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])=C([H])C(=C1[H])C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]([O-])=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C3=C([H])C([H])=C(N=C23)C2=NN=C3C([H])=C([H])C([H])=C([H])N23)C([H])([H])C1([H])[H]
[H]O[C@@]1(C2=C([H])C([H])=C(F)C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])N(C(=O)[C@@]2([H])C([H])([H])N(C3=C([H])C([H])=C([H])N=N3)C([H])([H])[C@]2([H])C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(O1)C(\[H])=C1\C(=O)N(N=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])[H]
[H]OC(=O)C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1C(=O)O[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])N(C(=O)C([H])([H])[H])C(=O)C(=O)N(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=NSN=C1N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])C(=O)N(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(N([H])C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(SC1=NC2=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2S1)C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])=C([H])[C@@]23C4=C(O[C@@]2([H])C1([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C4C([H])([H])N(C([H])([H])C(=C([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H]
O=C(NCCCN1CCCC1=O)C1=CN=C(NCC2=CC=CC=C2)N=C1NC1CCCC1
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N2C(=O)N(C3=C(C2=O)C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2F)C1([H])[H]
O=P(NCC1=CC=CN=C1C1=CC(=CC=C1)C#N)(C1=CC=CC=C1)C1=CC=CC=C1
[H]OC1=C([H])C(=C2OC(=O)SC2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]OC1=C([H])C(Br)=C2OC(=NC2=C1[H])C1=C(F)C(=C(O[H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])N=N1)C([H])([H])C#N
CCCCCN1C=C(C(=O)NC2CCCCC2)C(=O)C2=C1N(C)N=C2C(C)(C)C
CC1=C(Cl)C=CC=C1C(=O)N1CCC[C@@H](C1)C1=NC(=NO1)C12CC3CC(CC(C3)C1)C2
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C1=NC2=C([H])C([H])=C(F)C([H])=C2N2C1=NN=C2C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C(C([H])=C1[H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C(=O)N(C([H])=C1[H])C([H])([H])[H]
[H]O[C@@]1(OC(=O)C(=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C(C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C3[C@@](O[H])(OC2=C(Br)C1=O)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])[C@]3(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(O[H])C(\C([H])=N\N([H])C(=S)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])N1C2=C(OC([H])([H])C1([H])[H])C([H])=C([H])C(F)=C2[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[S@@](=O)C([H])([H])[C@]([H])(N([H])C1=O)C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(\C([H])=C2/C(=O)/C(=C(/[H])C3=C([H])C([H])=C(C([H])=C3[H])C(=N[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]([H])(O[H])C([H])([H])N1C(=O)C(OC2=C([H])C([H])=C(F)C([H])=C2F)=C([H])C2=C1N=C(N=C2[H])N([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])N=C1[H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
OC[C@@H](NC(=O)C1=CC=NC2=CC=CC=C12)C(=O)N1CCC[C@H]1B(O)O
[H]N(C(=O)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(C([H])=C(C([H])=N1)C1=C([H])N(N=C1[H])C([H])([H])[H])C1=NC2=C(O1)C([H])=C(Cl)C([H])=C2[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)N(C1=O)[C@@]([H])(C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1F
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C(O[H])C([H])=C2[H])[C@@]2([H])[S@+]([O-])[C@]1([H])[C@@]1([H])C(=O)N(C(=O)[C@@]21[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=C(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C2N(C(=O)C([H])([H])[C@]2(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C(F)=C(F)C([H])=C1F
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[H]
[H]C1=C([H])C(OC(=O)N2C([H])([H])C([H])([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])=C([H])C([H])=C1Br
NC1(CCC1)C1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=C(Br)C=C1
[H]O[C@]([H])(C([H])([H])OC1=C2SC([H])([H])C(=O)N([H])C2=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(Cl)C(=C1[H])S(=O)(=O)N([H])[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])OC2=C(C(O[H])=C([H])C(O[H])=C2[H])C(=O)C1([H])[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(N(C([H])([H])[H])S(=O)(=O)C2=C1SC([H])=C2[H])C(=O)N([H])C1=NC([H])=C(S1)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])N2C(=O)N(N=C12)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]\C(C1=C(N(N=C1C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])=C1/C(=O)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]C1=C(N=C(N1C1=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1F)C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(SC([H])([H])C(=O)N([H])C2=C(C#N)C3=C(S2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(\C([H])=C(/[H])C2=C([H])C([H])=C(O2)C([H])([H])[H])=C3[H])=NN1[H]
[H]OC1=C([H])\C(=N\C2=C3C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C3=NC([H])=N2)C(=O)C([H])=C1N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])N=C(C(Cl)=N1)[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
CCCC1=C(N=C(NC2=CC=CC(=C2)S(N)(=O)=O)N=C1)C1=C(C)N=C(NC)S1
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=NC([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(C([H])=C(OC([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])=C1[H])[C@@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])[C@]([H])(O[H])C([H])([H])[C@]4([H])C([H])([H])[C@@]([H])(OC([H])([H])C([H])([H])N(C5=C([H])C([H])=C(C([H])=C5[H])[C@]5([H])C6=C7C(=C([H])C(=O)C([H])([H])C7([H])[H])C([H])([H])C([H])([H])[C@@]6([H])[C@]6([H])C([H])([H])C([H])([H])[C@@](O[H])(C#C[H])[C@@]6(C([H])([H])[H])C5([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])[C@]([H])(O[H])[C@]12C([H])([H])[H]
[H]N=C(N([H])[H])N(C([H])([H])[H])C([H])([H])C(=O)N([H])C1=C(I)C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC1=NC2=C([H])C(C#C[C@@]([H])(N3C([H])([H])C([H])([H])C([H])(C([H])([H])C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])[H])=C([H])C([H])=C2N1[H]
[H]C1=C(C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1N=C(C([H])([H])[H])[C@@]([H])(\N=N\C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])C2=NC([H])=C([H])C([H])=N2)C1=O
CCCN1CCCC(C1)C1=NC2=C(C=NC=C2N1)C(N)=O
[H]OC([H])([H])C(\[H])=C1/[C@@]2([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]1(N([H])[H])C1=C(N([H])C(=O)C([H])=C1[H])C2([H])[H]
[H]O[C@@]([H])(C1=C([H])C(OC2=C([H])C(Cl)=C(Cl)C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])S(=O)(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)P(=O)(O[H])O[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N(C(=O)C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]\C(=C(/C1=NC(=NO1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C2=C([H])C([H])=C([H])N=C12)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C2=NC([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C2=C(N([H])C(=O)C([H])=C2C(F)(F)F)C([H])=C1[H])C([H])([H])C(F)(F)C(F)(F)F
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC3=C(S2)C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N1C(=O)N(C2=NC(=C([H])C(N3N=C(C([H])=C3[H])C3=NC([H])=C([H])S3)=C12)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1C(F)(F)F)C(F)(F)F
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]N(C([H])([H])C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O[N+]([O-])=O
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])[C@]([H])(N([H])[C@]([H])(C(=O)O[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C1=O
[H]C1=C([H])C(=C([H])C(F)=C1[H])C(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(=C([H])C([H])=C1[H])C1=NN(N=N1)C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]\C(=N/N1C([H])=NN=C1[H])C1=C(N(C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C([H])=C(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C(Cl)=C([H])N=C(N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=[N+]2[O-])C1=O)C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])[H]
[H]OC1=C(Cl)C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C(Cl)=C(OC([H])([H])C4=NC5=C(S4)C([H])=C([H])C([H])=C5[H])C([H])=C3[H])C2=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2(C([H])([H])O1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(OC2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])C(=O)N1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@@]12C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]1([H])C([H])([H])[H])C2([H])[H]
CC1=C(CCN)[Se]C(N)=N1
[H]C1=C(F)C([H])=C(F)C(=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])[C@]2(C3=C(C([H])=C(C(Cl)=C3[H])C([H])([H])[H])[C@]([H])(C2([H])[H])C(C(=O)N2C([H])([H])C(F)(F)C2([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(O[C@]([H])(N2C(=O)C([H])([H])C([H])([H])[H])C2=C(OC([H])([H])[H])C([H])=C([H])C(Br)=C2[H])N=C(SC([H])([H])C([H])([H])[H])N=N1
[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N2C(=O)N(N=C2[C@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(C1=C2N=C(N(C2=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C([H])(C1([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NN=C(O1)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1N(C(=O)C([H])([H])OC(=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2C(N([H])C([H])=C2C2=C([H])N=C([H])O2)=C1[H]
[H]N(C1=C([H])C([H])=C([H])C(Br)=C1[H])C1=NC([H])=NC2=C1C([H])=C1C([H])=C([H])N(C1=C2[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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[H]N1C([H])=C([H])N=C1[C@]1([H])C2=C(C(=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
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[H]O[C@@]1(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N1C([H])([H])C([H])([H])C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])N([H])C2=O)C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])SC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(Br)=C(OC2=C([H])C([H])=C(O[H])C(OC3=C([H])C([H])=C(O[H])C([H])=C3[H])=C2[H])C(Br)=C1[H]
FC1=CC=C2C=CC=C(N3CCN(CCCOC4=C(F)C=C5CNC(=O)C5=C4)CC3)C2=C1
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[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])SC1=NC2=C([H])C([H])=C([H])C([H])=C2S1)C1=NC(=C([H])S1)C([H])([H])[H]
[H]N(C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=NC(=C([H])S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C(N=NN2C2=C1SC([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C(=C2[H])C2=C(C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])=C1F
[H]OC(=O)C([H])([H])SC1=C([H])C(=C([H])N2C(=O)C3=C(SC([H])=C3C3=C([H])C([H])=C([H])C([H])=C3[H])N=C12)C(=O)C1=C([H])C([H])=C([H])C([H])=C1O[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H])N1C(=O)C2=C([H])C([H])=C(F)C([H])=C2N=C1C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)[C@]2([H])C([H])=C([H])C([H])([H])N3N2C(=O)N(C3=O)[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])SC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)C(SC([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1(C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]\C(C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H])=C1/C(=NC([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])[P@](=O)(OC([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C(N(C2=C1C([H])=NC(=N2)C#N)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@@](C1=NC2=C([H])C([H])=C([H])C([H])=C2S1)(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC1=NC(=C(N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(F)C([H])=C(F)C([H])=C1[H]
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CC(C)(C)OC(=O)N1CCN(CC1)S(=O)(=O)C1=CC=C(NC(=O)\C=C/Cl)C=C1
[H]OC([H])([H])[C@@]1([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2C2=C(Cl)C([H])=NC(=N2)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])S(=O)(=O)C2=C([H])C([H])=C3C([H])=C([H])C([H])=C(Cl)C3=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C1=NC2=C(OC([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2C([H])=C1[H]
CC1=CN=CC(OC2=C(Cl)C=C(NS(=O)(=O)C3=CC=C(Cl)C=C3Cl)C=C2Cl)=C1
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C(=O)O[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(\C(=C1/C(=O)N([H])C2=C([H])C(=C([H])C([H])=C12)C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)S1)C1=NN(C([H])=C1[H])C([H])([H])C(=O)N([H])C1=C(F)C([H])=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C([H])C1=O
[H]O[C@]([H])(C(=O)N([H])N([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)[C@]([H])(N([H])[H])C([H])([H])SC([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(Br)=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(N([H])C2=C3C([H])=NN(C3=NC([H])=N2)C2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(=C(/[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])=NC([H])=C1[H])\C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C([H])C(F)=C(F)C(F)=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])(C2=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
CCCC1=C(C(=O)OCC)C(C(=O)OCC)=C2N1N=C(C=C2CCC)N1CCOCC1
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C([H])N2C1=C(C(=O)C(=O)N([H])[H])C(=C2C([H])([H])C1=C([H])SC(=C1[H])C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])[H]
[H]N1C(=NC2=C1C([H])=C([H])C(=C2[H])N1C([H])=NC2=C(SC(=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])OC1=C2C(=C([H])C([H])=C1[H])N(C(=C2C(=O)C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(F)C([H])=C2C(=C1[H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=NN1[H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C([H])([H])O[C@@]1([H])C([H])([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(C([H])([H])N([H])C2=C([H])C([H])=C([H])C([H])=N2)C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C([H])N=C12)N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]OC1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])=C(O2)C1=C([H])C(O[H])=C(O[H])C(O[H])=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])N=C(N=C1[H])N([H])C1=NN=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC(=O)C([H])([H])N([H])C(=O)[C@]([H])(C2=C([H])C([H])=C(N([H])C3=C([H])C([H])=NC(=C3[H])C(F)(F)F)C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(OC(F)(F)F)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])S(=O)(=O)C(F)(F)F
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C2=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])O[H])C([H])([H])C([H])([H])SC([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
CC(C)C1=CC=C(SC2=CN=C(O)C(=C2)C#N)C=C1
[H]N([H])C(=O)C1=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])N=C(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(Cl)C2=C(C([H])=C1Cl)C([H])([H])N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=NC(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C(N([H])C2=NC([H])=C3C([H])=C(C(=O)N(C3=N2)C([H])([H])[H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)=C1[H]
[H]N1C2=C([H])C(C#CC3=C([H])C([H])=C(F)C([H])=C3[H])=C([H])C([H])=C2N=C(C2=C([H])C([H])=C([H])C(=C2[H])N2N=C([H])N=C2[H])C([H])([H])C1=O
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C([H])C(F)=C(C([H])=C2[H])C2=C([H])C3=C(O2)C([H])=C([H])C(=C3[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(N2C([H])=C(Br)C([H])=C(Br)C2=N1)C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(\C1=C([H])C([H])=NC([H])=C1[H])=C1\C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])OC([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(OC([H])([H])[C@@]2([H])N(C(=O)C([H])([H])C3=C([H])C([H])=C(N([H])C(=O)N([H])C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])[H])C(Cl)=C3[H])C([H])([H])[C@@]([H])(F)C2([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])SC1([H])[H])C([H])([H])SC([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C1(C2=NN=C3N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])[C@@]([H])(OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[C@]2([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)C([H])([H])C(=O)OC([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]O[C@]([H])(C([H])([H])SC([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)[C@]1([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@@]([H])(O[C@]2([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]2([H])OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]1([H])OC(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N(C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])N([H])C(=O)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C(=O)N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])O[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(O[C@@]([H])(C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C1[H])C1=NC([H])=C([H])S1
[H]N([H])C1=NC(N([H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])=C([H])C(=N1)N1C([H])([H])C([H])(N([H])C([H])([H])[H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])N([H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N=C(N([H])C1=C(Br)C(=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])N(C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2N(C(=C3[H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])N2C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C(F)C([H])=C1F)C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N([H])C(=O)N(C1=O)[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C1=NN([H])N=N1
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]ON(C([H])=O)[C@@](C([H])([H])[H])(C([H])([H])[C@@]([H])(C1=NC([H])=C(F)C([H])=N1)C([H])([H])[H])C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C2=C(Br)C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(=NC3=C1C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C#CC([H])([H])N([H])C1=C([H])C([H])=NC2=C1C1=C(S2)C(=O)N(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])[H])C(F)=C1[H]
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C([H])([H])N(C(=O)\C(=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C2OC3=C(OC([H])([H])[H])C([H])=C4C(=C3[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C4([H])[H])C([H])([H])C3=C([H])C([H])=C(OC4=C5C(=C([H])C(OC([H])([H])[H])=C4O[H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])[C@]5([H])C([H])([H])C(C([H])=C1[H])=C2[H])C([H])=C3[H]
[H]N1C([H])([H])[C@@]2([H])C([H])([H])N(C(=O)C3=C([H])C(Br)=C([H])O3)C([H])([H])[C@@]2([H])C1([H])[H]
[H]N(C1=C(N=C2N=C([H])C([H])=C([H])N12)C1=C([H])C([H])=C2N([H])N=C([H])C2=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])SC1=C2C(=C(S1)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2=O
[H]N1N([H])C(=NC1=S)N1C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C1=C([H])C([H])=C2N(C([H])=NC2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(C(=O)N([H])C3=C2C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])[C@@]1([H])C(=O)N(C([H])([H])C(F)(F)F)C([H])([H])[C@]([H])(C2=C(F)C(F)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N=C1N(C2=C(C([H])=C([H])C([H])=C2N1C([H])([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
COC1=CC=C(OC2=C(Cl)C=NN(CC3=CC=CC=C3C3=CC=CC=C3)C2=O)C=C1
[H]OC1=C(C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NN([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H]
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[H]C#CC([H])([H])N1C(=O)N(C2=C(N(C(=N2)C(\[H])=C(/[H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])[H])C1=O)C([H])([H])[H]
OB(O)C1=CC=CC=C1F
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[H]N(C(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])S2)C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)C([H])([H])O[C@@]1([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(N([H])C(=O)N([H])C2=C(C([H])=C(S2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N2C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])=C1C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
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[H]OC1=C([H])C2=C(C(SC([H])([H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])=N1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C2=C(N([H])C3=C2C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C1[H]
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[H]OC([H])([H])[C@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
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[H]OC(=O)C(=C(/[H])C1=C([H])N=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])\C([H])([H])C1=C([H])C([H])=C(S1)C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(C1=C([H])C([H])=C(C(Cl)=C1[H])C([H])([H])N([H])C1([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
CCCCCC1=CC=CC=C1C1=CC=C(OC(CC2=CC=CC=C2)C(O)=O)C=C1
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[H]C1=C([H])N(C([H])=N1)[C@]([H])(C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])OC2=C([H])C([H])=C([H])C([H])=C2C1=O
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[H]N(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C2N([H])N=C(C3=C([H])C4=C(N3[H])C([H])=C(C([H])=C4[H])C([H])([H])[H])C2=C1[H]
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[H]OC(=O)[C@@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C(C([H])=C([H])N=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C(C2=C1OC(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])C([H])([H])[H]
NC1=C(C=CC(NCCNC2=NC=C(C3=NC=CN3)C(=N2)C2=C(Cl)C=C(Cl)C=C2)=N1)N(O)=O
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC2=C(N(N=C2C(=O)OC([H])([H])C([H])([H])[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[C@@]2([H])O[C@@]([H])(C3=C([H])C(Cl)=C([H])C([H])=C3N3C([H])=C([H])C([H])=C23)C2=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@]1(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2F)C([H])([H])C2=NN([H])C(=O)C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)\C([H])=C1/[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[P@](=O)(C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C(=NO1)C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C1\SC(=NC1=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C#N)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@](N([H])[H])(C([H])([H])OP(=O)(O[H])O[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1Cl)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=NC(C2=C([H])N=C(S2)C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N1C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C21
[H]N(C1=C([H])C([H])=C(SC2=NC([H])=C([H])N2C([H])([H])[H])C(Cl)=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(\C([H])=C(/[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C12
[Cl-].NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CCC1=CC=CC=C1)B(O)O
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1N=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C2(OC(=O)C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]SC([H])([H])[C@]([H])(N([H])[H])C([H])([H])N([H])[C@]([H])(C(=O)N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=NC([H])=C1C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N([H])C([H])([H])[C@]1([H])N(C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(C#CC1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])C1=C2N=C([H])C(=NC2=NN1[H])N([H])C1=C(F)C([H])=C(F)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])OC([H])([H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])C([H])([H])N([H])[H])C([H])([H])[C@]2(SC([H])([H])C([H])([H])S2)C1([H])[H]
[H]O[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)ON=C1C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(C([H])=C(S2)C([H])([H])C([H])([H])[H])C(=O)N(C1=O)C([H])([H])C(=O)C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C(Cl)C([H])=C([H])C(=C1[H])N1N=NN=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N(C1=C2N([H])C(=NC2=NC(=N1)N([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C(N(N=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)C1=C(C(=O)N([H])C1=O)C1=C([H])C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1C(=NN=C1C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]2(O[H])C(=O)C([H])([H])SC2=NN=C(O2)C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C(=O)C([H])=C([H])[C@]3(C([H])([H])[H])[C@@]12[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=C1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])C3=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N4C(=O)C([H])([H])C([H])([H])C4([H])[H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])=C2OC1([H])[H]
[H]OP(=O)(O[H])[C@]([H])(C(=O)N([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])N([H])C([H])([H])[H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(Br)C([H])=N1
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H]
CN(C)CC[C@H](CSC1=CC=CC=C1)NC1=CC=C(C=C1[N+]([O-])=O)S(=O)(=O)NC1=CC=C(C=C1)N1CCN(CC1)C1=CC(=CC=C1)C1=C(N(C)C(C)=C1C#N)C1=CC=C(Cl)C=C1
[H]OC(=O)C1=C([H])C(F)=C(C(N([H])C(=O)C2=NC3=C(S2)C([H])([H])N(C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=NN=C(O2)N([H])C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C2N(C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C(=O)O[C@@]([H])(C1([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C([H])S2)C2=NOC(=N2)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])SC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1O[H])C(=O)N([H])C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC([H])([H])[H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@](N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(N=C1C1=NN=C(O1)C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])=C2[H])N(C2=C([H])C3=C(C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC(=NC(=N1)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])N2C(=NC(=C(C2=O)C2=C([H])C([H])=C(C#N)C([H])=C2[H])[C@]([H])(N(C(=O)C([H])([H])C2=C([H])C(=C(F)C([H])=C2[H])C(F)(F)F)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=NN(C(=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C2C([H])=C([H])C([H])=NC2=C([H])C([H])=C1[H]
[H]C([H])=C(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])=C(\C(=N\N([H])C(=O)C2=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])=C2[H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])O\N=C(\C([H])([H])N1C([H])=NC([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)[C@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(C(=O)C([H])([H])[H])C1=NC(=C([H])S1)C([H])([H])[C@@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=NN2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C(F)C([H])=C([H])C([H])=C2F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C(=O)N2C3=C(C([H])=C([H])C(=C3[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C2=NC(=NC(=C2C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(SC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=N1
[H]N(C(=O)C1=C(N([H])C(=N1)C(F)(F)F)C1=C([H])C([H])=C(F)C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C(N([H])C2=C([H])C3=C(N=C([H])N(C3=O)C([H])([H])[H])C([H])=C2[H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])[C@]2([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]\C(=C(\[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(C(=O)C([H])([H])[H])C(=O)C2=C([H])C(=C([H])C(Cl)=C2N1[H])[N+]([O-])=O
[H]OC(=O)C([H])([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C(F)=C1F)C(=O)N([H])[C@]([H])(C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N=C2C([H])=C(C([H])=C([H])N12)S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC4=C([H])C5=C(N([H])C([H])=C5C([H])([H])C([H])([H])N([H])[H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])=C12
[H]N=C(N([H])C1=C(F)C(=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])[H])N(C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C([H])C([H])=C([H])C([H])=C4N=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(F)=C([H])C(F)=C2[H])C([H])([H])[C@]1([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
CC1=C(CC(O)=O)C2=CC(F)=CC=C2\C1=C/C1=CC=C(C=C1)C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])[C@@]11C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NN([H])N=N1
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]3([H])C([H])([H])C1=C2C(OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H])C1=C2C([H])=NN(C2=NC([H])=N1)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C(N(C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)[C@@]3([H])[C@@]([H])(C2=O)[C@]2([H])C([H])=C([H])[C@@]3([H])[C@@]3([H])C([H])([H])C([H])([H])[C@@]23[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1=O
[H]C1=C(N(N=N1)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])[C@]1([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(C(=NC(=N1)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])N([H])[H]
[H]N(C(=O)C1=NC(C#N)=C([H])N1[H])C1=C(C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=NC2=C(C(=NN12)C([H])([H])[H])C1=C([H])N=C(OC([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C([H])([H])C(=O)N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]OC1=C(C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])[C@@]([H])(C(=O)[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(I)C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C2=C([H])C(=C([H])C([H])=C2OC([H])([H])[H])N2N=NN=C2C(F)(F)F)[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
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[H]N([H])C1=C(C([H])=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
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[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC1=C([H])C([H])=C(N([H])C2=NC3=C(C([H])=C([H])C([H])=C3C3=NN=C([H])N3[H])C3=C([H])N=C([H])C([H])=C23)C(Cl)=C1[H]
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FC1=CC(OC2=C(C(=O)N3CCNCC3)C3=CC=CC=C3N2C2=CC=CC=C2)=CC=C1
[H]C1=C(C2=C(Cl)N=C([H])N=C2N1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)C([H])([H])SC1=NC(=NN1C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
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[H]C1=C([H])C([H])=C2N(N=NC2=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H]
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[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)C1=NN=C(O1)C1(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
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[H]N1C([H])=C(N2C(Cl)=C(Cl)C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(N([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]C1=C(OC2=C1C([H])=C(C([H])=C2[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
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[H]N([H])C1=NC2=C([H])C([H])=C3N(C([H])=C([H])C3=C2C(=N1)N([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[C@@]([H])(C#N)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(OC([H])([H])[C@]3([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C23)=C1[H]
CCC1=CC=C(C=C1)C(CCCN)(C1=CC=CC=C1)C1=CC=CC=C1
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C2(N(C3=C([H])C(F)=C(F)C([H])=C3[H])C([H])([H])N([H])C2=O)C([H])([H])C1([H])[H]
[H]O[C@@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N1C([H])([H])C([H])([H])C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])N([H])C2=O)C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C(=O)N(C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1N=C([H])C2=C1C1=C(SC3=C1N=C([H])N(C3=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])N=C2[H]
[H]C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[N@@+]23C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]([H])(OC(=O)C2(C4=C(C([H])=C([H])C([H])=C4[H])C4=C2C([H])=C([H])C([H])=C4[H])C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C([H])=C([H])C([H])=NC2=C([H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)[C@@]([H])(C1=NN=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=NC(=NC(=C1[H])N(C([H])([H])C1=C([H])C([H])=C(C#CC([H])([H])N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C#N
[H]N([H])C1=NC2=C(S1)C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=NC4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(OC([H])([H])[C@@]3([H])OC4=C(C([H])=C([H])C([H])=C4[H])N(C([H])([H])[H])C3([H])[H])C([H])=C2[H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C2=NC3=C(N=NN3[C@]34C([H])([H])[C@@]5([H])C([H])([H])[C@]([H])(C([H])([H])[C@](O[H])(C5([H])[H])C3([H])[H])C4([H])[H])C([H])=N2)C([H])=C1[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@]1([H])C2=C([H])C([H])=C(N=C2OC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN=C([H])S1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=NC(=C(C(=O)OC([H])([H])[H])[C@]2([H])C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H][C@]12CCCN1[C@@]1([C@@H](CC(=O)N3C\C(=C/C4=CC=C(Cl)C=C4)C(=O)[C@]4(C[C@@]5([H])CCCN5[C@@]44C(=O)NC5=C4C=CC=C5)C3)C2)C(=O)NC2=C1C=CC=C2
[H]N(C(=O)C1=C(Cl)C(=C([H])S1)C([H])([H])N(C1=NC([H])([H])C([H])([H])O1)C([H])([H])[H])C1=C(C([H])=C(Cl)C([H])=C1OC([H])([H])[H])C(=O)N([H])C1=NC([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=N1)C(=O)N([H])C1=NN=C(S1)S(=O)(=O)N([H])[H]
[H]N(C(=O)C1(N([H])C(=O)C2=C([H])N=C([H])N=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C1=C(F)C([H])=C(C([H])=C1[H])N1N=C(Cl)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C(C(=O)C2=C(O[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C(=O)C([H])([H])[H])=C([H])C([H])=C1OC1=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
COC1=CC=C(C=C1)C1=NNC(NC(=O)CCCCN2CCCCCC2)=C1
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=NN(C2=C1C([H])=C([H])C(OC1=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C13)=C2[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C1=C(C([H])=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])C3=C(C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])[H])C([H])=C2OC1([H])[H]
[H]N([H])C([H])([H])C([H])([H])N1N(C(=O)C(C(=O)N([H])C2=C([H])C([H])=C(OC3=C([H])C([H])=NC4=C([H])C(OC([H])([H])[H])=C([H])C([H])=C34)C(F)=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C2=C([H])C([H])=C(OC3=C4C([H])=C(C(=O)C([H])([H])[H])C(OC([H])([H])[H])=C([H])C4=NC([H])=C3[H])C([H])=C2OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C(=O)C(=O)[C@@]([H])(N([H])C(=O)C1=C(C([H])=C([H])C(=O)N1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
OC(=O)CCC1=CC=C(OCC2=C(C=CC=C2)C2=CC=C(Cl)C=C2)C=C1
[H]N1C(=N[C@](C2=C([H])C([H])=C(F)N=C2[H])(C2=C([H])C([H])=C(F)C([H])=C2[H])[C@]1([H])C([H])([H])[H])C1=C([H])C([H])=C(C(=O)N1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N2C(=NC(=C(C(=O)OC([H])([H])[H])[C@]2([H])C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])\N=C(/S[H])N([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C(=NC2=C1C([H])=C([H])C(Cl)=C2[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N2C3=C(C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C(=C([H])N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C1SC([H])=C(N1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C(=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C([H])C(=O)O2)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(ON=C1C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C(C2=C(O1)C([H])=C([H])C(=C2[H])C1=C([H])C([H])=C(N=N1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[S@](=O)C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C1=NN=C(N1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N1N=C(N=C1C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(C([H])=C1[H])N1C([H])([H])[C@]2([H])C([H])([H])[C@@]1([H])C([H])([H])[N+]2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])\C(\[H])=C(/[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C([H])([H])C1=NC([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C(C(=C1[H])[N+]1=NN=NN1C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]\C(=C1\C2=C([H])C([H])=C(F)C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC1=NC2=C([H])C(Cl)=C(C([H])=C2C(OC([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]2([H])[H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=NN=C([H])S1
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N([H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C(C([H])=C1Cl)C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
CCCS(=O)(=O)N1CCN(CC1)C1(CNC(=O)C2=C(Cl)C=C(Cl)C=C2)CCCCC1
[H]C1=NC(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)N(C(=O)N(C1=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
C\C=C(/C)C(=O)NC1=NN=C(S1)C1=CC=C(C=C1)C(O)=O
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[H]N(C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
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COC1=CC=C(C=C1)C(C1=CC=NC=C1)C1=CC2=C3N(CCC3=C1)C(=O)CC2
[H]N(C(=O)C1=C(Cl)C(=C([H])S1)C([H])([H])N(C1=NC([H])=C([H])O1)C([H])([H])[H])C1=C(C([H])=C(Cl)C([H])=C1OC([H])([H])[H])C(=O)N([H])C1=NC([H])=C(Cl)C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C(OC([H])([H])[H])N=C3[H])C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]C1=C(C2=C(C([H])=C([H])C([H])=C2[H])N1S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C(C([H])=C(Cl)C(=N1)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2O[C@@]([H])(C([H])([H])[H])C(F)(F)F)S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
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[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])SC(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)[C@@]2([H])OC3=C(C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C(C2=C([H])OC3=C([H])C(OC([H])([H])C4([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C([H])=C23)=C(C1=O)C1=C([H])N(C2=C([H])C(Cl)=C(F)C([H])=C12)C([H])([H])[H]
[H]N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=C1C(=O)N(C(=O)C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C2C(N([H])N=C2C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C1=NN=C(S1)C1=C([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2N=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(C1=C([H])C(=C([H])C([H])=C1[H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]N1C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C3=NC([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C(=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(Cl)=C(C([H])=C1[H])C1=NOC(=C1C(=O)C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C2=C(N([H])C(=O)OC2([H])[H])C([H])=C1[H]
[H]N1N=C(C(=C([H])C1=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N([H])C1=C([H])C([H])=C(OC3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C1[H])C2([H])[H]
[H]N([H])[C@]([H])(C([H])([H])N1C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@]2(OC(=O)C2=C([H])C([H])=C([H])O2)C(=O)C([H])([H])SC2=NC3=C(S2)C([H])=C([H])C([H])=N3)[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C(=O)C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]12[H]
CC(C)C[C@H](NC(=O)NC1=C(Br)C=CC=C1)C(=O)NO
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C([H])=C2[H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])[S@](=O)C([H])([H])C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])[C@@]([H])([C@]1([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(\N=N\C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]OC1=NSC(N([H])C2=C([H])C([H])=C(N([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])=C1C(=N[H])N([H])C([H])([H])C([H])([H])O[H]
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[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C(=O)N(C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(=C([H])C([H])=C2O1)C(=N[H])N([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N([H])C2=O
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[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
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[H]C1=C(N=C(N1C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]O[P@](=O)(C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(N=C(C#N)C#N)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C2N=C(N=C([H])C2=C1[H])N([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C(C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]OC(C1=C([H])N=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=C3C([H])=C([H])C([H])=C([H])C3=C(N=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C2C([H])=C(C(=NC2=N1)N([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C([H])C(C#CC2=C([H])N=C3C([H])=C([H])C([H])=C([H])N23)=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C1([H])[H])C(F)(F)F
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[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C3C([H])=C([H])N([H])C3=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(\N=C(\OC1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C#N
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(S1)C(\[H])=C(/[H])C(=O)N([H])C1=NC([H])([H])C([H])([H])C([H])([H])N1[H]
[H]N([H])C1=NC2=C([H])C(=C([H])C([H])=C2C(=N1)N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])[H])[C@@]([H])(O[H])C1([H])[H]
[H]N([H])C1=NN([H])C2=C1C([H])=C([H])C(=C2[H])N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(F)C([H])=C([H])C([H])=C1F)C1=C([H])N([H])N=C1C(=O)N([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NC2=NC(=NC([H])=C2C([H])=C1C1=C(Cl)C([H])=C([H])C([H])=C1Cl)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(OC([H])([H])C(=O)OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(C#N)C(=C1[H])C(F)(F)F
[H]OC([H])([H])[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1N=C(C([H])=C2[H])C1=NN=C2C([H])=C([H])C([H])=C([H])N12)C([H])([H])C([H])([H])[H]
[H]N1C2=C(C3=C(C([H])=C2[H])C2=C([H])C(F)=C([H])C([H])=C2O\C3=C(\[H])C([H])=O)C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(Br)=C(N([H])S(=O)(=O)C(F)(F)F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)O[C@]1(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@]2([H])[C@]3([H])C([H])([H])C([H])([H])C4=C([H])C(=O)C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
ON(=O)C1=CC(NC2=C3N=CNC3=NC(=N2)N2CCOCC2)=CC=C1
[H]OC([H])([H])C(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1N=C(C([H])=C2[H])C1=NN=C2C([H])=C([H])C([H])=C([H])N12)(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C(O[H])=C(C([H])=C2C([H])([H])C([H])([H])[H])C2=NN([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]2([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N1N=C(N=C1C1=NC([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C([H])C([H])=NC([H])=C3C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=NC2=C(S1)C([H])=C([H])C(N([H])C(=O)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C2[H]
[H]O[C@@](C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])[C@@]1([H])OC([H])([H])C([H])([H])N([H])C1([H])[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC([H])=NC2=C1N=C([H])N2[C@]1([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]1([H])O[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@]1([H])OC1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C1=C([H])C(=NN1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(SC([H])=C1[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C1=C(N([H])C(=O)C([H])([H])[C@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(C#N)(C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC2=C1N=C([H])N2[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C2N=C([H])N([H])C2=NC([H])=N1)[C@]([H])(C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N1N=C(C2=C(C1=O)C([H])([H])C([H])([H])C([H])([H])N2[H])C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(I)=C1[H])C([H])([H])SC1=NN=C(O1)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C(=O)N(C([H])=C2[H])C([H])([H])[H])[C@@]([H])(C(=O)N(C([H])([H])C2=C([H])C(=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C2([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C(=O)OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H]
[H]N1C(C#N)=C(SC2=C([H])C([H])=C([H])C([H])=C2Cl)C2=C([H])C([H])=C(C([H])=C12)S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C1=C(S2)C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N1C(=O)C2=C([H])C(F)=C([H])C([H])=C2N=C1C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])=C([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])N(C(=C1[H])C(=N[H])N([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N1N=C(C2=NC([H])=C([H])S2)\C(=C(/[H])C2=C([H])N(C3=C([H])C4=C(OC([H])([H])O4)C([H])=C23)C([H])([H])[H])C1=O
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N2C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C(OC(=O)C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(N=NN2C([H])([H])C2=C([H])C([H])=C([H])C(F)=C2F)C(=N1)C1=C([H])C([H])=C([H])O1
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC2=C([H])C([H])=C(C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])C1=C([H])C(=C(N1C([H])([H])[H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C2=C([H])C(OC([H])([H])OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N=C(C1=C(N([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C(N=C3[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)[C@@]2(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)C1=C(Cl)C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C(C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=C(Br)N=C1OC([H])([H])[H])S(=O)(=O)C1=C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C([H])C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)N(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N=[N+]=[N-])C(I)=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(F)=C([H])C(=C1[H])C(=O)C1=C(C([H])=C2OC([H])([H])OC2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]\C(C(=O)C1=C([H])N=C([H])C([H])=C1[H])=C1/C(=O)N(C(=O)OC([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C(Cl)=C12
[H]N(C(=O)C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N2C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])[C@@]2([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])OC1=C([H])C(F)=C([H])C(F)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C(=O)C1=C(N(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C(OC([H])([H])C(=O)OC([H])([H])[H])=C12)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])N1C(SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=NN=C1C1=C([H])C([H])=C([H])C([H])=N1
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C2N(C([H])([H])[H])C([H])([H])[C@](OC2=C1[H])(C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H]
[H]OC1=C2O[C@@]3(C(=O)C([H])([H])C([H])([H])[C@]4(OC([H])([H])[H])[C@@]5([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]34C2=C(C([H])=C1[H])C5([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C(=O)C1=C([H])C([H])=C(O1)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C1([H])[H]
[H]N(C1=C(N([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])[H])C(=O)C1=O)C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C2=C(N([H])C1=O)C([H])=C([H])C([H])=C2[H]
[H]N(C1=NN(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C12)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)S1
[H]N(C(=O)OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C2=C1C([H])([H])N([H])C2=O
[H]N(C1=NN([H])C(=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C(F)C([H])=NC(=N1)N([H])[C@]([H])(C1=NC([H])=C(F)C([H])=N1)C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=NN(\C(S1)=N/S(=O)(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C(F)C(F)=C(F)C(F)=C2F)C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(F)C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C(OC1=C([H])C([H])=C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2F)C(F)(F)F)C([H])=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])N([C@]([H])(C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C3=C([H])C4=C(OC([H])([H])O4)C([H])=C3[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(F)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N(N=NC2=N1)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C2([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(Cl)C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)O[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C(OC([H])([H])C(=O)N3C([H])([H])C([H])([H])N(C4=C([H])C([H])=C(N([H])C(=O)C([H])([H])OC5=C([H])C6=C(N([H])C([H])=C6C([H])([H])C([H])([H])N([H])[H])C([H])=C5[H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])=C12
[H]N1C(=O)C2=C3C(N([H])C4=C3C([H])=C(C([H])=C4[H])C3=C([H])SC(=N3)C([H])([H])[H])=C3C(=C2C1=O)C([H])([H])C([H])([H])C3([H])[H]
[H]N1C2=C(I)C(=O)C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3([H])[C@]2([H])C1([H])[H]
[H]N(C(=O)C1=NN2C(N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C23)=C1[H])C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C2N=C([H])C([H])=C([H])C2=C(C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])S3)C(=N2)C2=C([H])C([H])=C([H])S2)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])N(C(=O)C1=C([H])C2=C(N=C(O2)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C#C[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])N=C([H])S1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(N=C1[C@@]1([H])C([H])([H])C([H])([H])[C@]3(OC(=O)C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C1([H])[H])C([H])=C(C([H])=C2[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]2(O[H])C(=O)C([H])([H])SC2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=N2)[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C(=O)C([H])=C([H])[C@]3(C([H])([H])[H])[C@@]12[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])N1C(=NC(=C1C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(F)(F)F
[H]OC(=O)C1=C(OC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C2=NN([H])N=N2)C(=NC2=C([H])C([H])=C([H])C(=C12)C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
ON(=O)C1=CC=C(NC(CC(=O)C2=CC=C(C=C2)C2CCCCC2)C2=CC(F)=CC=C2)C=C1
[H]N(C(=O)C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC([H])([H])C([H])([H])N2C([H])([H])[H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]ON(C(=S)N([H])C([H])([H])[C@@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])N(C(=O)[C@]3([H])N([H])C([H])([H])C4=C(C([H])=C([H])C([H])=C4[H])C3([H])[H])C([H])([H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(C3=C1C1(C([H])([H])N(C([H])([H])C([H])([H])[H])C1([H])[H])C([H])([H])N([H])C3=O)C([H])([H])C([H])([H])C1=C2C([H])=C(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)C([H])([H])[H])C1=C(N([H])C2=C([H])C([H])=C(C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C(Cl)=C2[H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C([H])C2=C1N=C([H])C(=C2[H])S(=O)(=O)C1=C([H])C([H])=C2N(C3=C(C2=C1[H])[C@@]1([H])N([H])[C@]([H])(C([H])([H])C1([H])[H])C3([H])[H])C([H])([H])[H]
[H]N(C1=C(C(=C([H])C([H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])SC(=C2[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C1=C(S2)C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])[H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N(C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])([H])SSC([H])([H])[C@@]([H])(N([H])C1=O)C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=C(/[H])C([H])([H])C1=C(O[H])C2=C(C(=C1C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])OC2=O)\C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C(Cl)=C(C([H])=C3[H])N3C([H])=NC([H])=C3[H])C2=C1[H]
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NN=C(S1)N([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C2OC(=C([H])C2=C1[H])C1=C(N([H])C2=C([H])C([H])=C3N([H])C([H])=C([H])C3=C2C([H])([H])[H])C(C#N)=C([H])N=C1[H]
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[H]N([H])C(=O)N([H])C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\[H])C3=C([H])C(=C([H])N3[H])C3=C([H])C(=C([H])C([H])=C3[H])C(=O)N([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C2=C1[H]
[H]N(C(=O)C1=C(N=C([H])S1)C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1F)C([H])([H])[H]
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[H]OC([H])([H])C1(N([H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(=N1)N([H])C(SC1=C([H])C([H])=C([H])C3=C1C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2C([H])([H])[H]
[H]C1=C(N(N=N1)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C3=C(C([H])=C4C([H])=C([H])C([H])=C([H])C4=N3)C([H])([H])[C@@]12[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
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[H]N1C(=O)C([H])([H])C2=C([H])C(=C([H])C([H])=C12)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C2=NC3=C(N=NN3[C@]34C([H])([H])[C@@]5([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C5([H])[H])C3([H])[H])C4([H])[H])C([H])=N2)C([H])=C1[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C#N)C([H])([H])C([H])([H])N1C(=O)N(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=NN([H])C(=S)S1
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C(N2C([H])=C(N=C2N=C1C([H])([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C2=C(C([H])=C1[H])C1=NC3=C([H])C([H])=C(F)C([H])=C3C(C([O-])=O)=C1SC2([H])[H])C([H])([H])[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C1=C([H])C(Cl)=C(OC([H])([H])[H])C(Cl)=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]C1=C2N=C(Cl)C3=C(C(=O)N(C3=O)C([H])([H])C([H])([H])OC(=O)C([H])([H])[H])C2=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])SC1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(N([H])C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C2C(=C([H])C([H])=C1[H])N(C(=C2C(=O)C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]C1=NC([H])=C(C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]\C(I)=C(\[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])OC2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NOC(=N1)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C(=C([H])N=C1C([H])([H])[H])C([H])([H])O[H])C([H])([H])N([H])C1=NC(=NC(=N1)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])N([H])C([H])([H])C1=C(O[H])C(=NC([H])=C1C([H])([H])O[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC2=C(S1)C([H])=C(OC([H])([H])[H])C([H])=C2[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N2C(=O)N([H])C(=C(C(=O)N([H])[H])[C@]2([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
CC(=O)N1CCN(CCOC2=CC=C(C=C2)C2CCN(CC2)C2=NN3C(CC2)=NN=C3C(F)(F)F)CC1
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[H]N(C(=O)OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
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[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])C(=O)O[H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]S\C(=N/[C@]([H])(C(=O)OC([H])([H])C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N(C(=O)C([H])([H])[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=NN(C(=C2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])OC([H])([H])N1C([H])=NC2=C1N([H])C([H])=NC([H])([H])[C@@]2([H])O[H]
COC1=CC=C(C=C1)C1=CC=NC(NC(P(O)(O)=O)P(O)(O)=O)=C1
[H]N([H])C([H])([H])C1=C([H])SC(=N1)C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])[H]
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[H]N([H])C1=NC2=C([H])C([H])=C(Cl)C([H])=C2N2C1=NN=C2C(F)(F)F
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[H]OC(=O)C1=C([H])C([H])=C(N=C1N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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