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[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC1=NC(OC2=C([H])C(=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])N([H])[H])=C(F)C([H])=C1F)C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])N2C(=O)N([H])[C@@]([H])(C2=O)C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
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[H]O\C(=C(\SC1=C([H])C([H])=C([H])C([H])=C1[H])/C(/[H])=C(/[H])C(=O)C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])[C@@]([H])(O[H])C([H])([H])N2[H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C(Br)=C1O[H]
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[H]O[C@@]1([H])C2=C(N([H])C([H])=NC1([H])[H])N(C([H])=N2)C([H])([H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]N([H])C1=NC(=C([H])C(=N1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)N([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1N=C(C2=C1C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C(F)(F)F
[H]N([H])C1=NC2=C(SC3=C([H])C(Br)=C([H])C([H])=C23)C(=N1)N1C([H])([H])[C@@]2([H])N([H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N([H])C([H])([H])[C@]1([H])N(C([H])([H])C2=C(Cl)C(F)=C([H])C([H])=C2F)C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(N([H])C2=C3C([H])=NN(C3=NC(=N2)N([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])N=C([H])C([H])=C1[H])S(=O)(=O)C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=N1)C1=C([H])N=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])C(F)(F)F
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C2N([H])C(=O)N([H])C3(C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=NC2=C1C([H])=C([H])C(=N2)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C(=NN2C2=C([H])C([H])=C([H])C([H])=C2C1=O)C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=NC(=NC2=C1C([H])([H])C([H])([H])N(C1=NC([H])=C([H])C([H])=C1C(F)(F)F)C([H])([H])C2([H])[H])N(C([H])([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
CC(NC(=O)C1=CC=C2OC(=NC2=C1)C1=CC=NC=C1)C1=CC=CC=C1
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]13C([H])([H])N(C([H])([H])C4(O[H])C([H])([H])C4([H])[H])C([H])([H])C([H])([H])[C@]21C([H])([H])C(=O)C([H])([H])C3([H])[H]
[H]N(C(=O)C1=C([H])N(N=C1[H])C([H])([H])[H])C([H])([H])C1=C(N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O)C(=O)OC([H])([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=N2)C(=NC2=C1C([H])=C(Cl)C(Cl)=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC1=C(C(=C([H])C([H])=C1N([H])C1=C(N([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(=O)C1=O)C([H])([H])[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])ON1C(=O)[C@@]2([H])[C@@]3([H])O[C@]([H])(C([H])=C3[H])[C@@]2([H])C1=O
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[H]C1=C([H])C2=C(C([H])=C1[H])C(C1=C2C([H])=C([H])C([H])=C1[H])=C1C(=O)N(C(=O)C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
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[H]OC(=O)C1=C(O[H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C(O[H])=C2O[H])C([H])=C1[H]
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[H]OC(=O)C1=C(OC2=NC(OC3=C([H])C([H])=C([H])C(=C3[H])C(=N[H])N([H])[H])=C(F)C(N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2F)C([H])=C([H])C(=C1[H])C([H])([H])[H]
FC(F)(F)C1=CC=CC(NC(=O)NC2=CC=C(C=C2)N2CCN3C=CC4=NC=NC2=C34)=C1
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[H]N1C(=O)C(C2=C([H])C(=NO2)C([H])([H])[H])=C(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C2=C([H])C(Cl)=C([H])C([H])=C12
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CCCCN(C(=O)C1=CC=C(C=C1)C(F)(F)F)C1=NN=C(S1)C1=CC(CO)=CC=C1
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[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N2N=C([H])C(C#N)=C(N([H])C3=C([H])C([H])=C(OC4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C2=C1C([H])([H])[H]
[H]N(N(C#N)C([H])([H])[H])C(=O)O[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C2OC([H])([H])C([H])([H])C2=C([H])C(Cl)=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])C(F)=C1N([H])C1=C(Cl)C([H])=NC(=N1)N([H])C1=C([H])C([H])=C2C(=C1[H])N(C(=O)C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)[C@@](N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C2\C(=O)C(C3=C4C(=NC5=C4C([H])=C([H])C([H])=C5[H])\C(=C(\[H])C4=C([H])C([H])=C(O[H])C([H])=C4[H])C3=O)=C3C2=NC2=C3C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
O\C(\C=C\C1=CC=CC=C1)=C/C(=O)C1=CC=CC=C1O
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[H]N(C(=O)C([H])([H])N1C(=O)OC2=C1C([H])=C([H])C(=C2[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])C(=O)C2=C(O[H])C([H])=C(O[H])C(OC([H])([H])[H])=C2O1
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[H]C1=C([H])C(=C([H])C([H])=C1C#N)N1C(C#N)=C(N=C1[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
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[H]N([H])C1=N[C@@](C(=O)N1C([H])([H])[H])(C1=C([H])SC([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C(F)N=C([H])C([H])=C1[H]
[H]N1C(=O)N(C2=C(N=C(SC3=C([H])C([H])=C(Cl)C([H])=C3Cl)C([H])=C2[H])C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
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[H]C1=C(N=C2C([H])=C([H])C(Cl)=C([H])N12)C([H])([H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=NC([H])=C([H])C([H])=N3)C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C1=C([H])N=C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])C([H])=C1[H]
[H]N1N=C([H])C2=C1C(=C([H])C(=C2[H])C([H])([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C2(OC(=O)N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(N([H])C(=O)C([H])([H])N2C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=N[H])N([H])[H]
[H]C([H])=C([H])C(=O)N([H])C1=C([H])C2=C(C([H])=C1[H])C(=NC([H])=N2)N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])[H])[C@]1([H])OC(=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])O[C@@]([H])(C([H])([H])[C@@]2([H])O[C@]([H])(OC([H])([H])C2([H])[H])\C([H])=C([H])\C(C([H])([H])[H])(C([H])([H])[H])[C@]2(O[H])O[C@@]([H])(C([H])([H])\C(=C(\[H])C(=O)OC([H])([H])[H])[C@]2([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])S[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])S[H])C([H])([H])C(=O)O[H])[C@]([H])(O[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C(N=C1[H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
[H]C1=NC([H])=C2N1C([H])([H])C1=C([H])C(OC3=C([H])C4=C(C([H])=C([H])C([H])=C4C([H])=C3[H])N(C(=O)C([H])([H])N(C([H])([H])[H])C2([H])[H])C([H])([H])[H])=C(C#N)C([H])=C1[H]
[H]N(C1=NC(N([H])C2=C(C([H])=C([H])C([H])=C2[H])S(=O)(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1OC([H])([H])[H]
[H]O\N=C(/[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C(O[H])C(F)=C2[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C(C([H])=C([H])C(=N1)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2O[C@@]([H])(C([H])([H])[H])C(F)(F)F)S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]C1=C([H])N(C([H])=N1)C([H])([H])C([H])([H])OC1=C([H])C(=O)OC2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C(=N\OC([H])([H])C1=C(N=C(S1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H])\C([H])([H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C(=C2N=C(SC2=C1C([H])([H])C([H])([H])[H])N([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])C(=O)N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]2(OC([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])[N+]1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C(C(=C([H])S2)C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N(C1=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
CN1CCN(CC1)C1CC2=C(SC3=C1C=C(C=C3)C1=CC=CC=N1)C=CC=C2
[H]N([H])C1=C([H])C([H])=C([H])C2=C1C1=C3C(=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C2([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(F)=C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])N([C@]([H])(C4=C([H])C([H])=C(C([H])=C4[H])S(=O)(=O)C4=C([H])C5=C(OC([H])([H])O5)C([H])=C4[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C3([H])[H])C([H])([H])C2([H])[H])C(F)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=NC(=C1C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C2C([H])=C([H])N(C2=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C1=C([H])N=C([H])C([H])=C1N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1N1N=NN=C1[H]
[H]N([H])C1=C([H])C(=NC2=C(C([H])=NN12)C1=C([H])C([H])=NS1)[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])N(C1=NC(=C([H])S1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=S)N1N=C(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])O[C@]12C([H])([H])C([H])([H])C(=O)[C@]3([H])OC4=C5C(=C([H])C([H])=C4OC([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@@]235
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C3C4=C([H])C([H])=C([H])C([H])=C4C(=O)C(N=C1[H])=C23)C([H])([H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1C([H])=C1C(N([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])=C2[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C([H])=O)C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1C(=O)N([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2N=C(OC2=C1[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1(C2=C([H])C([H])=C(F)C([H])=C2[H])[C@@]2([H])C([H])([H])[C@@]3([H])C([H])([H])[C@]1([H])C([H])([H])[C@](OC([H])([H])[H])(C3([H])[H])C2([H])[H]