[H]N(N1C([H])([H])C([H])=C(C2=C([H])C([H])=C3N([H])C([H])=C(C3=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C(=S)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C3C(=C1[H])C1=C(C([H])=C([H])C(O[H])=C1O[H])C([H])([H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])N(C(=O)C1=C([H])C(O[H])=C(O[H])C([H])=C21)C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)[C@](N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N(C1=C2C(=NC3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=NC2=C(C([H])=C1[H])C([H])=C([H])C1=C(C([H])=C([H])C(Cl)=C1[H])[C@]2([H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N([H])C1(C2=NC3=C(S2)C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]C1=NN(C(=C1C1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])S(F)(=O)=O
[H]N(C(=O)N(C1=NC([H])=NC(N([H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]ON([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C3=C(C([H])=C2[H])N2C([H])=NN=C2C2=C(C([H])=C(O2)C2=C([H])C([H])=C(C#N)C([H])=C2[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=O)N2C([H])=C([H])C([H])=C(C3=NN=C(S3)N3C([H])([H])C([H])([H])C([H])(N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C2=N1
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(N(C(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(OC([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C3=C(C([H])=C2[H])N2C(=NC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C3=O)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC(=O)N(C([H])([H])[H])C([H])([H])[H])=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(SC([H])([H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])=NN=C1C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])C1=NC(N([H])[H])=C2C3=C(C([H])=C([H])C2=N1)N(C([H])=C3[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[C@]2([H])N([H])C(=O)N([H])C2=O)C([H])=C1[H]
[H]N(C(=O)C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H]
CC(=O)C1=CC=C(C=C1)C(=O)N1CCOC2=CC=C(C=C2C1)C1=CC=C2C=NNC2=C1
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])SC([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C2=C(N([H])C3=C2C2=C(C(=O)N([H])C2=O)C2=C3C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([C@]1([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C1=C(C([H])=C([H])C(Cl)=C1[H])C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)S1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])C([H])=C([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])=C([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])[C@@]1([H])SC2=C(C([H])=C(F)C([H])=C2[H])[C@@]1([H])OC([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N([H])C1=NOC2=C([H])C([H])=C(C([H])=C12)N1N=C(C([H])=C1C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])N=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(=O)N2C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])OC(=O)C1=C([H])N=C([H])C(=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@]([H])(N([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H]
[H]C([H])([H])[C@@]12C(=O)C([H])([H])C([H])([H])[C@]1([H])[C@]1([H])C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]1([H])C(=O)C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=NC(=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C2C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=NC([H])=C2[H])N1C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)N1C([H])([H])C([H])(OC([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(O1)C([H])([H])N1C([H])=C(C(=O)N=C1SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])N2C(=O)N(N=C12)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C(\[H])=C(/[H])C1=C([H])N=C([H])N1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])OC(=O)N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]\C(=C(\[H])C([H])([H])SC1=NC2=C([H])C([H])=C(C([H])=C2C(=O)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
OB(O)CCCCC[C@H](NC(=O)C1=CN=CS1)C(=O)NC1=CC(=CC=C1)C1=CC=CC=C1
[H]OC1(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])OC(=O)N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N(C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1N=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]1([H])C(=O)N([H])[C@](C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C2=C(SC(Cl)=C2[H])N1[H]
[H]C1=C(ON=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])[C@]2([H])S[C@@]1([H])C([H])([H])C2([H])[H]
[H]N(C1=NC([H])=C2C(=C1[H])N(N=C2C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C(O2)C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C([H])([H])O[H]
[H]C1=C(N(C2=C1C([H])=NC(=N2)C#N)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=NS2)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C([H])C([H])=C([H])C([H])=C3C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@](C(=O)N([H])C1=C(Cl)C([H])=C(C([H])=C1[H])N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])(C([H])([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])=O
[H]N(C1=C2C([H])=NN(C2=NC(SC([H])([H])[H])=N1)C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
FC1=CC=CC(=C1)S(=O)(=O)NC1CCN(CC2=CC=C(C=C2)C2=NN=C3N2C2=CC=CN=C2NC2=C3C=CC=C2)CC1
[H]N(C1=NC([H])=C([H])C([H])=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C([H])=N3)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1N2C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])[C@]([H])(N(C([H])([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])[H]
[H]OC1=NC([H])=C([H])N1C([H])([H])[C@](O[H])(C1=C([H])C(O[C@@]2([H])C([H])([H])OC([H])([H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C(Cl)C(Cl)=C1[H])C([H])([H])N1C2=NC(=C([H])C(=O)N2N=C1C1([H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=N1)C([H])([H])N([H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=C([H])C2=C(OC(F)(F)O2)C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C(=O)OC([H])([H])[H])C(=C1[H])C(=O)OC([H])([H])[H])S(=O)(=O)C1=C(C2=C(S1)C([H])=C([H])C(Cl)=C2[H])C([H])([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2N(C(=N3)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C(C2=C([H])C3=C([H])N=C([H])C([H])=C3N2[H])=C1O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])[C@]([H])(O[H])C([H])([H])O[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])O[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(C(=O)OC(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2N=C1[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[N+]([O-])=O)S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[C@]1([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N([H])C1=NC2=C(N=C(C([H])=C2[H])C([H])([H])N([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])[H])C(=N1)N([H])[H]
[H]C1=C([H])C([H])=C(C(OC2=C([H])C([H])=C(C#N)C([H])=C2[H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
ClC1=C(Cl)C=C(C=C1)C1=NC2=C(C=CC=C2)N1C1=CC=NC(N[C@@H]2CCCN(C2)C(=O)C2CC2)=N1
[H]C1=NC(Cl)=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C3C(=C([H])C(=O)C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]2([H])[C@]2([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C(=O)C3([H])C([H])([H])C3([H])[H])[C@@]2(C([H])([H])[H])C1([H])[H]
[H]C1=C2N(N=C1C([H])(C([H])([H])[H])C([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2C1=NN(C(=O)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NN(C2=C1[C@]1(O[C@@]([H])(OC([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(Cl)=C([H])C([H])=C2O1
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])Cl)C([H])([H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])SC([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C2C([H])=C(OC([H])([H])[H])C(\C([H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C([H])C2=NC([H])=C1C#N
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])[C@]([H])(C2=C(F)C([H])=C(F)C(F)=C2[H])[C@@]([H])(N([H])[H])C1([H])[H]
COC(=O)C1C2CCC(CC1C1=CC=C(F)C=C1)N2CCC[N+]12CCS[Re]11(=O)SCCN1C(=O)C2
[H]O[C@@]1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@@]1([H])N([H])C(=O)C1=C([H])N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C([H])([H])O[C@@]1([H])C([H])([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(C([H])([H])N([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=N2)C1([H])[H]
[H]N(C1=NC(=NN1C(=O)C1=C([H])C([H])=C([H])O1)C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])O1
OC(=O)CCC1=CC=C(OCC2=CC(=CC=C2)C#N)C=C1
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])[C@]([H])(OC(=O)N([H])C([H])([H])C([H])([H])N(C4=C([H])C([H])=C(C([H])=C4[H])[C@]4([H])C5=C6C(=C([H])C(=O)C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@@]5([H])[C@]5([H])C([H])([H])C([H])([H])[C@@](O[H])(C#C[H])[C@@]5(C([H])([H])[H])C4([H])[H])C([H])([H])[H])C([H])([H])[C@]4([H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])[C@]([H])(O[H])[C@]12C([H])([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C(N([H])C(=O)N([H])[C@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]N(C([H])=O)C1=C([H])C2=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1N2[H]
ON(=O)C1=CC=C(NC(CC(=O)C2=CC=C(Br)C=C2)C2=CC=C(C=C2)C(F)(F)F)C=C1
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC2=C([H])C(=C([H])C(=C2[H])C(=O)OC([H])([H])[H])C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])SC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C(OC([H])([H])C2=C([H])C(F)=C(F)C([H])=C2[H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C(C2=NC3=C(N2[H])C([H])=C([H])C([H])=C3[H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12)[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(OC2=C([H])C3=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])N([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C([H])([H])N(C1=C([H])C([H])=C(C#N)C(Cl)=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
C[C@@H](C(=O)NC1=CC=C2OC(=NC2=C1)C1=CC=NC=C1)C1=CC=CC(Cl)=C1Cl
[H]N1C(=S)N([H])\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C(=C(C([H])=C2Br)C([H])([H])[H])C([H])([H])[H])C1=O
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(=O)OC([H])([H])C(=O)N([H])C1=C(C([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]C1=NN(C([H])=C1N1C([H])=C([H])C2=C(N(N=N2)[C@]([H])(C2=C([H])C([H])=C3N=C([H])C([H])=C([H])C3=C2[H])C([H])([H])[H])C1=O)C([H])([H])[H]
[H]N1C([H])=C(C#N)C2=C([H])C(=C([H])C([H])=C12)[C@]1(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C(C([H])=C2[H])C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=NC3=C2C([H])=C([H])N3[H])C([H])([H])C1([H])[H]
[H]C1=C(N(N=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Cl)C(Cl)=C([H])C([H])=C1[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(=O)N(C(=O)C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C(N2C([H])=C([H])C([H])=C([H])C2=N1)C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]S\C(=N/N([H])C1=C([H])C([H])=C(C([H])=C1[N+]([O-])=O)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])N([H])C1([H])C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(OC([H])([H])C([H])([H])[H])C(=C([H])C([H])=C1N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C(=N1)N(C([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C#CC1=C([H])C([H])=C(C#CC([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N(C([H])([H])C2=C(N=C3N2C(=O)C(=C([H])N3C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2F)C(=O)OC([H])([H])C([H])([H])[H])C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=NC(=N1)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)[C@]([H])(OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2N([H])C2=NC([H])=C(O2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=NC3=C([H])C(=C([H])C([H])=C3N2C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)C(=O)N([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=NC([H])=C(OC(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]2([H])C3=C(C([H])=C([H])C([H])=N3)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C2=C(N([H])N=C2C2=C([H])C(=C(C([H])=C12)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2C2=C1C1=C(N([H])C(C([H])=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H]
[H]N1C([H])=NC([H])=C1C([H])([H])[C@]1([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])OC2=C([H])C([H])=C3N([H])C(=O)C([H])=C(C3=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C([H])N=C([H])C([H])=C2N1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C(C(=O)C([H])([H])C([H])([H])N21)C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])(F)F)C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C(=O)[C@@]1([H])C([H])([H])[C@]1([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])N(C(=O)C([H])([H])C([H])([H])[C@@]1([H])F)C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C(=O)N1C([H])([H])C2=C(C(=NC(=N2)C2=C([H])C([H])=C([H])O2)C(F)(F)F)C([H])([H])C1([H])[H]
CC(C)=CC1=C2OC(=C(O)C(=O)C2=C(O)C=C1O)C1=CC=CC=C1
[H]OC(=O)[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])=C(C3=C([H])C([H])=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=NC(=C(S1)C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C(C2=C([H])C([H])=C(F)C([H])=C2[H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])N1C(=O)C2=C([H])C3=C(C([H])=C2C1=O)C([H])=C(C([H])=C3[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C(=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N(C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(/[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(OC2=C(N([H])S(=O)(=O)C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C(C([H])=C2[H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]C1=C([H])C(=C([H])C(C#N)=C1[H])C1=NN=C(S1)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]\C(=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]ON(C(=O)N([H])[H])C([H])([H])C1=C([H])C2=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2O[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])N=C([H])C(=C1[H])C1=C([H])N=C2N([H])C([H])=C(C2=C1[H])C1=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)C(F)(F)C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@]2([H])[C@@]3([H])C([H])([H])C([H])=C4C([H])([H])[C@@]([H])(O[H])C([H])([H])C([H])([H])[C@]4(\C([H])=C(\[H])Cl)[C@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])[H]
COCCCN1C(NC(=O)C2=CC(=CC=C2)C#N)=NC2=CC(=CC=C12)C(=O)NCC1=CC(OC)=CC=C1
[H]N(C1=C2C([H])=NN(C2=NC(SC([H])([H])[H])=N1)C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N1C([H])=NC2=C1C([H])=C([H])C(=C2[H])N1C(=O)C([H])([H])C(=O)[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])N=C1N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C2=C1[C@]1([H])N(C2=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C([H])=C(Br)C(=C1[H])N1N=NC2=C1N=C(N=C2N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])C(Br)=C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1=O
[H]\C(=C1\OC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1Cl)C(=O)OC1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H])C([H])([H])[H]
[H]N(C1=C(C([H])=NC2=C1C([H])=NN2C([H])([H])[C@]([H])(Cl)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=N2)C(=O)N([H])C2=C([H])C([H])=C([H])C(N([H])C3=NC([H])=C(S3)C3=C([H])C([H])=C([H])N=C3[H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]\C(=C(\[H])[C@@]1([H])O[C@@]2(O[C@]1([H])C(\[H])=C(/[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C3=C(C([H])=NN3C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])[C@]21C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N=C(N([H])[H])N([H])\N=C(\C1=C([H])C(=C([H])C([H])=C1[H])C(=N\N([H])C(=N[H])N([H])[H])\C([H])([H])[H])C([H])([H])[H]
[H]N1[C@@]([H])(C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C3=C(C([H])=C2[H])N(C(=O)S3)C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])[C@]([H])(C#CC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[N+]([H])([H])[H])C([H])=C1[H]
[H]N=C1OC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2C([H])=C1C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(OC1=N[H])C(OC([H])([H])[H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=NC2=C(N([H])C([H])=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])C(=O)N(C2=C([H])C([H])([H])C([H])([H])[C@]2(C(=O)OC([H])([H])C([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])C3(C([H])([H])N(C4=C([H])C([H])=NC([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(I)C([H])=C1[H])C([H])([H])C#N
[H]N1C(=O)[C@@]([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[C@@]([H])(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)O[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])SC([H])([H])[C@]([H])(N([H])C1=O)C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1N=NC2=C1N=C(N=C2C1=C([H])C([H])=C([H])O1)N([H])[H]
[H]OC1=C([H])C([H])=C2C([H])=C1C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C(O[H])C(OC4=C(OC([H])([H])[H])C([H])=C5C(=C4[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C5([H])[H])C2=O)=C13
[H]N1C(=C([H])C2=C1C(F)=C([H])C([H])=C2[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC1=NN=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C3=C(C([H])=C2[H])N2C([H])=NN=C2C2=C(C([H])=C(O2)C2=C([H])C([H])=C(F)C([H])=C2[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C(F)C([H])=C([H])C(=C1[H])C(F)(F)F)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C(/[H])C2=C([H])C(=NO2)C([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H]
[H]N1C([H])=C(C2=C1C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3OC([H])([H])C([H])([H])OC3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=NC([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C(N([H])C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]S\C(=N/C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C1=C([H])C(=O)C(OC([H])([H])[H])=C([H])C1=O)C([H])([H])O[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(\C([H])=N\N([H])C(=O)C2=C(N(N=N2)C2=NON=C2N([H])[H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])C1=NC2=C(N1[H])C(=C([H])C([H])=C2[H])C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])N(C3=NC(N([H])[H])=C(N=C3Cl)C(=O)N([H])[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]ON(C(=O)C(\[H])=C(/[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C2SC(C#C[C@@]3([H])N([H])C([H])([H])[C@]([H])(OC(=O)N([H])C([H])([H])[H])C3([H])[H])=C([H])C2=NC([H])=N1)C1=C([H])C(Cl)=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN([H])C2=C1C([H])=C(C([H])=C2[H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
CC(=O)N[C@@H](CC1=CC(F)=CC(F)=C1)[C@H](O)CNC1(CCCCC1)C1=CC(O)=CC(=C1)C(C)(C)C
[H]OC(=O)C1=C(OC([H])([H])C(=O)O[H])C(Br)=C(S1)C1=C([H])C(N([H])C2([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N([H])C1=NC([H])=C2C([H])=C(C(=O)N(C2=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(C#N)=C([H])C(=C2O1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC2=C(N1[H])C([H])=C([H])C(=C2[H])C(N([H])[H])=[N+]([H])[H]
[H]N1C2=C([H])C(Cl)=C([H])C([H])=C2C(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@@]1([H])F
[H]N([H])C(C(=O)N1C([H])([H])C2=NC(=C(N([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])N2C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])([H])[C@]([H])(N([C@@]1([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=NN([H])C2=C1C([H])=NC(OC1=C(F)C([H])=C(F)C([H])=C1[H])=N2
[H]C1=C(Br)C([H])=C2C3=NC(=NN3C(SC([H])([H])C#N)=NC2=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C2=NC(=NC([H])=C2C2=NN=C(O2)C2([H])C([H])([H])C2([H])[H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3C([H])([H])SC2=C([H])C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)[C@]1([H])N(C(=O)OC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C2[H])C([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=O)[C@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(OC([H])([H])[C@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@@]1([H])N([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C3C(C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C34)=C2[H])[C@@]1([H])C(=O)O[H]
[H]OC1=NC([H])=C(N2C(=O)C3=C([H])C([H])=C([H])C([H])=C3C2=O)C(O[H])=N1
[H]OC(=O)[C@@]([H])(N([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]3([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]([H])(O[H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])S2)C([H])([H])O[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]N(C([H])=O)[C@]1([H])C2=C([H])C(=O)C(SC([H])([H])[H])=C([H])C([H])=C2C2=C(C([H])=C(OC(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(C(OC([H])([H])[H])=C(C2=C1C(=O)OC2([H])[H])C([H])([H])[H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])N(C([H])=O)C([H])([H])C([H])([H])P(=O)(O[H])O[H]
[H]C1=C(OC2=C1C([H])=C(C([H])=C2[H])C(=O)C1=C([H])C([H])=C(F)C(=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C(N([H])C(=O)N([H])[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2=C3C(N([H])C4=C3C([H])=C([H])C([H])=C4[H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N2C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C([H])C(=C([H])C([H])=C2C([H])([H])N1[H])C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1SC(C#C[C@@]1([H])N([H])C([H])([H])[C@]([H])(OS(=O)(=O)C([H])([H])[H])C1([H])[H])=C2[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C(Cl)=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])O[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H]
[H]OC1=C2N(N=C(C2=NC(=N1)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1(C([H])([H])N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)N2C([H])=NN=C2[H])C([H])([H])C1([H])[H]
CC1=NC=CC(COC2=CN=C(N=C2)N2CCN(CC2)C(=O)OC(C)(C)C)=C1
[H]N(C1=NC(=C([H])C([H])=C1C#N)C([H])([H])O[C@@]([H])(C1=C([H])N=C([H])N1C([H])([H])[H])C1=C([H])C(=C(C#N)C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1(C([H])([H])[H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(F)C(F)=C2N([H])C2=C(F)C([H])=C(I)C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=NC(=C([H])C([H])=C1[H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[3H]C1=CC=C(N2CCN(CC(=O)NC3=C([3H])C(C)=C([3H])C=C3[3H])CC2)C(=C1)C#N
[H]OC(=O)[C@]1([H])[C@]([H])(N(C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(Cl)=C(Cl)C(=O)O1
[H]OC(=O)[C@@]1([H])N([H])C([H])([H])C([H])([H])C2=C1N([H])C1=C([H])C([H])=C(OC([H])([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C21
[H]N1N=C(N(\N=C(/[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1=S)C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)N(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C(=O)C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H]
[H]N1N=NC(=N1)C1=C([H])C2=C(OC3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=NC([H])=C2S1
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C(N([H])C2=NC([H])=C([H])C(=N2)N([H])C2=C([H])C([H])=C([H])C([H])=C2Br)C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC1=NC(OC([H])([H])[H])=C([H])C(=N1)C([H])([H])[H])C(OC([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC3=C([H])C([H])=NN3C(N([H])C3=C([H])C([H])=C(F)C(Cl)=C3[H])=C2C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2N1C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=NC(=NO2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC([H])=C1C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])=NC([H])=C2C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=NC([H])=NC(N2C([H])([H])C([H])([H])N(C(=O)N([H])C3=C([H])C([H])=C(C([H])=C3[H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])=C1\C([H])=N\OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])C([H])=C1[H])C([H])([H])[H])[C@@]([H])(O[H])C(=O)N1C([H])([H])C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C(=O)C1=C(OC([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)C([H])=C(S1)C1=C([H])N=C(S1)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NOC2=C([H])C(=C([H])C([H])=C12)C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=O)C([H])(C#N)C(=O)C2=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2([H])N(C1=O)C([H])([H])C([H])([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C(OS(=O)(=O)C(F)(F)F)=C([H])C(=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C(C2=C([H])C([H])=NN2C([H])([H])[H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C(N=C(N1C1=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])SC([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1(N2C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[C@]3([H])N([H])C([H])([H])C4=C(C([H])=C([H])C([H])=C4[H])C3([H])[H])C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N1C(=O)C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C([H])C([H])=C1F)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]N1C(=O)C2=C(SC(=C2C([H])([H])[H])C([H])([H])[H])N=C1C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=NON=C12
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C(=O)C1=NC(=O)C2=C(N1[H])C([H])=C([H])C(=C2[H])[N+]([O-])=O
[H]O[C@@]([H])(C([H])([H])C(=C([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@](O[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])Br)C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C2C([H])=C([H])N=C3C4=C([H])C([H])=C([H])C([H])=C4C(=O)C(C([H])=C1[H])=C23)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])N=C(C(OC2([H])C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(F)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N([H])[H])C2([H])[H]
[H]C1=C([H])C(=C(SC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1C1=NN(C2=C1C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C(=O)C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C(C#N)C(=C(S1)C1=NC(=NO1)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])\N=C(\S[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C1=C(N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1I
[H]N([H])C1=C([H])C([H])=C([H])C2=C1C1=C(C([H])=C([H])C([H])=C1[H])C(=O)C2=O
[H]N(C(=O)C1=C2N=C(OC2=C([H])C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])N=C1O2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])OC1=C([H])C([H])=C(F)C2=C1OC([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(C2=C([H])C([H])=C([H])C(=N2)C([O-])=O)=C(C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2C([H])=C([H])C([H])=C([H])C2=C(C#N)N1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)N3C(=C(C2=O)C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C2=C(C([H])=N1)C(=NC([H])=N2)N([H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])C4=C(C#N)C(=O)C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)N2C([H])([H])C([H])=C(C3=C([H])C([H])=C(C#N)C([H])=C3C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[C@]2([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
CC[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(C)C)B1O[C@@H]2C[C@@H]3C[C@@H](C3(C)C)[C@]2(C)O1
[H]O[C@@]1(N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=NC(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=NC(=C(O1)C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C1([H])[H])C([H])([H])OC(=O)C1=C(C([H])=C(C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(Br)=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O[C@@]1(N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(\C(=N/C#N)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON(C(=O)N([H])C(=O)C([H])([H])[H])[C@]([H])(C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2S1)C([H])([H])[H]
[H]N(C1=NC([H])=C(N2C([H])=NC([H])=C12)C1=C([H])C([H])=C(OC([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1(C([H])([H])C([H])([H])[H])C([H])([H])OC1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NOC([H])=C1[H]
[H]OC(=O)C1=C([H])C(N([H])C(=O)C(F)(F)C(=O)[C@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N(C1=C([H])C([H])=C(C([H])=N1)[C@]([H])(C1=C([H])C([H])=C(OC([H])(F)F)C(OC([H])(F)F)=C1[H])C([H])([H])C1=C([H])C([H])=[N+]([O-])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=N/C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])[H])\N([H])[N+]([O-])=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C(C#N)=C([H])C([H])=C12)C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])OC1([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]3([H])C([H])([H])N2C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C2N(C(=O)C([H])([H])[C@]2(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1[H])S(=O)(=O)C1=C([H])C(F)=C(F)C([H])=C1F
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])C(N([H])S(=O)(=O)C1=C(O[H])C(N([H])C(=N\C#N)\N([H])C2=C(Br)C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1Cl)(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(N([H])N=C2C(=O)OC(OC2=O)(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]\C(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])=C1\C(=O)OC2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]N([H])C1=C([H])C([H])=C([H])C(C#CC2=C([H])C3=C(C([H])=C2[H])N(C2=C([H])C([H])=C([H])C([H])=C2C3=O)C([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=NC(N([H])[C@@]3([H])C([H])([H])[C@]([H])(N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C3([H])[H])=C([H])N=C2C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C(=O)OC3=C2C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])OC1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]2(C([H])([H])C([H])=C([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])C1=C([H])C([H])=C2C([H])=C([H])N(C2=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])S1
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@@]1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])F
[H]OC(=O)[C@@]1([H])N(C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(S[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])[C@]1([H])O[C@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=[N+]([O-])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C2C([H])=NN(C2=NC(SC([H])([H])[H])=N1)C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C2=C1C(F)=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]N([H])N([H])C(=O)[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C(SC2=C([H])C([H])=C(F)C([H])=C2[H])SC2=C([H])C([H])=C(F)C([H])=C12
[H]O[C@@]([H])(C1=C([H])C(Cl)=C(N([H])[H])C(Cl)=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C(OC(=C1[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C(SC([H])([H])[H])S1)C1=NC(=C([H])S1)C1=C(OC([H])([H])C([H])([H])C([H])([H])[H])N(N=C1[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C1=C(N=C2N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)[C@@]1([H])C([H])([H])N(C2=NC([H])=C([H])C(=C2[H])C2=C([H])C([H])=C(SC3=C(C([H])=C([H])C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C2[H])C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=[N+]([H])[H])C1=C(Cl)C([H])=C2N([H])C(=C([H])C2=C1[H])C1=C([O-])C(=C([H])C(=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C([H])N=C([H])N=C1N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]N(C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@]([H])(OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)O[H]
[H]C1=NC(=C([H])C([H])=C1[H])[C@@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C(OC([H])([H])[H])C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
[H]N([H])C(=O)N([H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]ON(C(=O)N([H])[H])C([H])([H])C([H])([H])C#C[C@]1([H])O[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NO[C@@](C(=O)N([H])C2=C([H])C([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])(C([H])([H])[H])C1([H])[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C([H])=C1Br)C([H])([H])C([H])([H])[H]
[H]C1=C(OC2=C1C([H])=C([H])C([H])=C2[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N(\C(S[H])=N\C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1(C(=O)OC([H])([H])C2=C1C([H])=C1N(C2=O)C([H])([H])C2=C(C3=C(\N=C(/[H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C3N=C12)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC1=NC(C2=C([H])C([H])=C([H])S2)=C(N1[H])C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]N1N=C(C([H])=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N(C([H])([H])C1=C([H])C([H])=[N+](C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])SC1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=NOC(=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C3=C(C([H])=NC(=N3)C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N([H])C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C2C(=C1[H])[C@](OC2([H])[H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])SC1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=NN1C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])[C@]2(OC3=C(C([H])=C([H])C([H])=C3[H])[C@@]([H])(O[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(S[H])[C@]([H])([N+]([H])([H])[H])C([H])([H])C([H])([H])S([O-])(=O)=O)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)O[H]
[H]OC1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])C([H])([H])C([H])([H])N([H])C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1[H])C([H])([H])SC1=C(C(=O)C2=C(O1)C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N=C([H])C(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])[C@]2(C(=O)N(C3=C([H])C(F)=C([H])C([H])=C3[H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
CC(C)(CO)NC(=O)C1=CNC2=C1N=C(C=N2)N1N=CC2=C1C=C(Cl)C=C2
[H]N([H])C([H])([H])C1=C(C2=C(N=C1C([H])([H])[H])C(=O)N(C([H])([H])C(=O)N([H])C1=C([H])C([H])=NN1C([H])([H])[H])C2([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N=C([H])C([H])=N1)N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C([H])=C(C1=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1F)C(F)(F)F
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C(C#N)=C2[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])[H])=C(OC([H])([H])[C@]2([H])OC([H])([H])C([H])([H])N(C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
CC(C)C1=CC=CC(Cl)=C1C(=O)N[C@@H](CC1=CC=C(C=C1)C1=C(C)N(C)C(=O)N(C)C1=O)C(O)=O
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N1[C@]([H])(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C([H])([H])N(C(=O)[C@]([H])(C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2OC([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
OB(O)[C@@H]1C[C@H](O)CN1C(=O)[C@@H]1C[C@@H](O)CN1
[H]N1C(=NC2=C1N([H])C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=C(Cl)SC(Cl)=C1C(=O)C([H])([H])Cl
[H]O[C@]([H])(C([H])([H])N([H])[C@@]1([H])C2=C(OC(=N2)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(SC([H])([H])C([H])([H])OC2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])=NC([H])=C1[H]
[H]C1=NC([N-]S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C(C(OC([H])([H])C([H])([H])OC2=NC([H])=C(OC([H])([H])[H])C([H])=N2)=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C(=O)C([H])([H])[C@@]1([H])OC([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])[C@@]2([H])C(=O)OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])N=C([H])S1)C1=NC([H])=C(N1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C([H])([H])[C@]1(C([H])=C(C2=C([H])C(F)=C([H])C([H])=C2F)C([H])([H])N1C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(F)F
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C(N([H])C(=O)C2=C([H])C(=C(OC([H])([H])[C@@]3([H])OC4=C(C([H])=C([H])C([H])=C4[H])N(C([H])([H])[H])C3([H])[H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C2N=C(N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]1(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])O3)C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C2N=C([H])C([H])=C([H])C2=C(Cl)C([H])=C1C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@@]1(O[H])C2=C(OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C([H])=C([H])C(=C2[H])[N+]([O-])=O
[H]N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=NC([H])=C2N1C1=C([H])C([H])=C([H])C([H])=C1N=C2C1=C([H])N=C([H])C([H])=C1[H]
[H]C1=C(OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])=C(O1)C([H])([H])OC(=O)C1=C([H])C([H])=C(OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C(=NN2C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(N([H])C(=O)C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N(\C([H])=C1/C(=O)N([H])C2=C([H])C([H])=C3N=C([H])SC3=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C1=C(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])N(C1=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N1C2=C(OC([H])([H])C1([H])[H])C([H])=C1C(=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])SC2=NN=C(N2C([H])([H])[H])C2=C3C([H])=C([H])C(=NC3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C#N
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(Cl)C2=C(C([H])=C1Cl)C([H])([H])N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C2([H])[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)\N=C1/SC(=NN1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])([H])C([H])([H])[H]
[H]OC1(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(C#N)(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(F)C(=C([H])C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C(Cl)=C1F)[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H]
[H]O[C@@](C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])(C([H])([H])C(C1=C([H])C(F)=C([H])C([H])=C1OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C1=C([H])C([H])=C(O[C@@]2([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C1=NC2=C(C([H])=C([H])C(=C2[H])C(=N[H])N([H])[H])N1C([H])([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2N=C3C(=N2)C(Br)=C(Br)C(Br)=C3Br)C([H])([H])C1([H])[H]
COC1=NC(C(=O)NCC2CCC2)=C(NC(=O)C2=C3C=CC=CC3=NC=C2)C=C1
[H]OC([H])([H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(S1)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2N(C(=C3C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C(=C2C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])[H])[C@]([H])(N1C([H])=NC2=C1N=C([H])N=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)C1=C([H])N(C(=O)C(C#N)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]([H])(C1=C([H])C2=C(C([H])=C1[H])C([H])=C(OC([H])([H])C1=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C1[H])C([H])=C2[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C1[H]
[H]S\C(=N/N=C(/C1=C([H])C(Br)=C([H])C([H])=C1[H])C([H])([H])[H])N([H])[H]
[H]N([H])C1=N[C@@](C2=C([H])C(=C([H])C(Br)=C2[H])C([H])([H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=N2)(C([H])([H])[H])C([H])([H])C([H])([H])S1
[H]N(\N=C(\C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C(=O)N([H])C1=NN([H])C(=S)S1
[H]N([H])C(N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C3=C1C([H])=C([H])C([H])=C3[H])C(=O)N([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])=[N+]([H])[H]
[H]C1=NC2=C(C([H])=C([H])C([H])=C2C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C(F)C([H])=C(F)C(=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=N1)[C@]([H])(C#N)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C1C([H])=C(C([H])=C2[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C1=C([H])C([H])=C(S1)C([H])([H])[H]
[H]N([H])C1=C2C([H])=C([H])C(=C([H])C2=NC([H])=N1)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C2=C([H])C3=C(N2[H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C1([H])[H]
COC1=C(F)C2=C(CN(C[C@]3(NC(=O)NC3=O)C#CC3=CC=C(N4C(=O)NC5(CC5)C4=O)C(F)=C3)C2=O)C=C1
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=NC2=C(C([H])=C(Cl)C([H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])SC(=N1)N([H])C(=N[H])N([H])[H]
[H]N(C(=O)C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])N=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])=C1[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C(Br)=C1OC([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])F
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H]
[H]N(C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C2C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C(=C1[H])C(F)(F)F
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C3=C1C([H])=C([H])C([H])=C3[H])C(=O)N([H])[H])C([H])([H])C1=C(C([H])=C([H])C(Br)=C1[H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1(C(=O)N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2C1=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC([H])([H])[H]
CC(=O)N[C@@H](CC1=CC(F)=CC(F)=C1)[C@H](O)CNC1(CCCCC1)C1=CC(NS(C)(=O)=O)=CC(=C1)C(C)(C)C
[H]N(C([H])([H])C([H])([H])C([H])([H])N(C1=NS(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C2C3=C([H])C([H])=C([H])C4=C3C(=C([H])C([H])=C4[H])C2=C([H])C2=[N+]1C(=C(S2)C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(Cl)=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])[H])C(Cl)=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C2N(C(=O)C(F)(F)C2=C([H])C([H])=C1[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(C2=C([H])C(OC3=C([H])C([H])=C([H])C(=C3[H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C2[H])=C2C([H])=C([H])C([H])=C(C2=N1)C(F)(F)F
[H]OC(=O)[C@]([H])(N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1C1=C(N([H])C(=O)C2=NC(=C(S2)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C(=NO1)C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=N2)C2=C([H])N=C3C([H])=C([H])C([H])=C([H])N23)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]([H])(C([O-])=O)C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C2=C1N=C(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN(C(=O)N21)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C(N=C(C(=N1)C([H])([H])C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C(=O)C1=C([H])C([H])=C([H])S1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]OC(C(=O)C([H])([H])N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C([H])([H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C2=NC(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=N2)C([H])([H])C1([H])[H]
[H]OC(=O)C(OC1=C([H])C2=C(C([H])=C1[H])N(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(N=N1)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])[C@]3(N(C(=O)[C@@]([H])(N([H])C3=O)C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C(N([H])C2=C(N([H])[C@@]([H])(C3=C([H])C([H])=NC([H])=C3[H])C([H])([H])C([H])([H])[H])C(=O)C2=O)C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N(N=N1)C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C#N)C1=C([H])C([H])=C([H])C(=C1N1C([H])([H])C([H])([H])C2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N1N=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C1C(=O)N(C2=O)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]OC1=C([H])C([H])=C(Br)C2=C1C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C2([H])[H]
[H]C1=NN(N=C1[H])C1=C(C([H])=C([H])C(C#N)=C1[H])C(=O)N1C([H])([H])[C@]([H])(OC2=NC([H])=C([H])C(C#N)=C2[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]O[C@]1(C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]O[C@@](C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H]
CC(C)(C)C1=CC(OC2=NC=CC=C2NC(=O)NC2=CC=C(F)C=C2F)=CC=C1
[H]C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C3=NN=C(C([H])=C3[H])C3=NOC(=N3)C(F)(F)F)C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])N=C4C([H])=C(C([H])=C([H])N34)C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C2C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])S(=O)(=O)C([H])([H])[H])C(OC([H])([H])[H])=C([H])C2=NC([H])=N1)C1=C(F)C(Cl)=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])[H])C1=C([H])SC2=C1N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)N1C(=O)N([H])C(=C(C(=O)OC([H])([H])[H])[C@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C3N([H])C4=C(C([H])=C([H])C([H])=C4[H])C3=C2[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])C(=O)C(F)(F)F
[H]OC1=C([H])C([H])=C2C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(N([H])C([H])([H])C([H])=C([H])[H])C([H])([H])C2([H])[H]
[H]N1N=C(N(\N=C(/[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C1=S)C1=C([H])C([H])=C([H])C([H])=N1
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])C([H])([H])C2=C([H])C(I)=C([H])C([H])=C2[H])N2N=C([H])C(=C2[H])C2=NC([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])ON=C3C4=C(C([H])=C([H])C([H])=C4[H])N(C([H])([H])[H])C([H])([H])[C@@]23[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C1=C2N([H])C([H])=NC2=NC([H])=N1
[H]N([H])C1=N[C@](C2=NC([H])([H])C([H])([H])C([H])([H])N12)(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2[C@](C1=O)(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@](C(=O)N([H])C1=C([H])C(=C(C#N)C([H])=C1[H])C(F)(F)F)(C([H])([H])[H])C([H])([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C(=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H])C([H])([H])C1(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C(=O)N([H])C1=O
[H]N(OC([H])([H])[H])C(=O)C1=C([H])C([H])=C(C(N([H])C2=NC(=NC(=N2)N(C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]
[H]N1C2=C([H])C(C#CC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])=C([H])C([H])=C2N=C(C2=C([H])C([H])=C([H])C(C#N)=C2[H])C([H])([H])C1=O
[H]C1=C([H])C(=C([H])C2=C1OC([H])([H])O2)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])N(C1=C([H])C(OC2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC(F)(F)C([H])(F)F)=C1[H])C(F)(F)F
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@]1([H])C([H])([H])[C@]2([H])O[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
FC(F)(F)C1=C2NC3=C(C=CC4=C3NC=C4C=O)C2=CC=C1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C([H])([H])[N+]1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]N(C(=S)N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)N(C([H])([H])[H])C([H])([H])[H])C(=C23)C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)C([H])([H])N([H])C([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(N=C(O1)C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])S[H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C(=O)N([H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1(N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(N([H])C2=NC([H])=C([H])C(=N2)C2=NC([H])=C([H])S2)C([H])=C1[H]
[H]ON([H])C(=O)C1=C([H])N=C2C(C([H])=C([H])C([H])=C2C([H])([H])[H])=C1N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])C1=C(N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]1([H])C3=C(C(=C([H])C([H])=C3[H])C3=C([H])C(F)=C([H])C(F)=C3[H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])N1C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]OC1=C2C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=N/C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])N([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])[H])\N([H])[N+]([O-])=O
[H]N(C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])[C@](C(=O)C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])[C@]([H])(OC([H])([H])[H])C#CC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]SC1=NC2=C(OC([H])([H])C([H])([H])N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2N1[H]
[H]C1=C([H])C(=NN(C1=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C(C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C([H])C(O[H])=C2C([H])=C1[H])C(F)(F)F
[H]N1N=C(SC1=S)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C([H])=C([H])C4=C([H])C([H])=C(F)C([H])=C34)C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=NC2=C([H])C([H])=C([H])C([H])=C12)C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])I
[H]C1=C([H])N(C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C(N=C3[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2OC1=O
[H]N(C(=O)C1=C([H])N=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@@]1([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])N1SC2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]C1=C([H])C2=C(C([H])=C([H])C(OS(=O)(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])=C2[H])N1C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(N=C=O)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])C([H])=C(OC([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2N=C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C3=C(C([H])=C(Cl)C(Cl)=C3[H])C2=O)C([H])([H])C1([H])[H]
[H]ON(\C([H])=C(\[H])C(=O)SC1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])[H]
[H]N1C2=C(N=C1[C@@]1([H])N(C(=O)C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])(C4=NC(=NO4)C4=NC([H])=C([H])C([H])=N4)C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])=C(Cl)C(Cl)=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N1C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C(N=C(S2)C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])S(=O)(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C#N
[H]C1=C([H])C([H])=C(S1)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H][C@@]12C[C@H](OC(=O)C3=CC=CC=C3Cl)[C@@]3(C)OC4=C([C@H](O)[C@]3([H])[C@@]1(C)CC[C@H](OC(C)=O)[C@@]2(C)COC(C)=O)C(=O)OC(=C4)C1=CN=CC=C1
C[C@@H](OC[C@]1(CC[C@@H](CN1)N1CCCC1=O)C1=CC=CC=C1)C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F
[H]ON([H])C(=O)[C@@]([H])(OC([H])([H])C1=C([H])C([H])=C([H])C2=C1N=C([H])C([H])=N2)[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])[C@]1([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=C(C(=O)C2=C([H])C(C#C[H])=C([H])C([H])=C2O1)[C@@]([H])(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(C(=NC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])SC([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C2C(=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C(N([H])C2=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NN=C(O1)C1=C2N(C([H])=C(C2=C([H])C(F)=C1[H])C([H])([H])[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C(F)=C(F)C([H])=C1F
[H]C1=C([H])C2=C(O1)C(=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]1([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(N([H])C1=O)C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C2=C(ON=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=N[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(N([H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=NN(C1=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H]
[H]OC1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1[H]
[H]N1C([H])=C(\C([H])=C2\C(=O)C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@](=O)(O[H])O[P@](=O)(O[H])OP(=O)(O[H])O[H])[C@@]1([H])O[H])N1C(=O)N([H])C(=C([H])C1=O)C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=NO[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C2=NC([H])=C([H])N2[H])C1([H])[H]
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C(F)=C([H])C([H])=C2O\C1=C(\[H])C1=C(C([H])=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NN=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(N=C([H])C([H])=C3C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])C2=O)C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C1C(=C([H])C([H])=C2[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC3=C(N2C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=C(N=C(S1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1C([H])([H])C([H])([H])[H])C1=NN([H])C(=C1C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])C2=C1OC([H])([H])C2=O
[H]C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])N2C(=O)N3C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C2=O)C([H])([H])C1([H])[H])[N+]([O-])=O
[H]N1C2=NC([H])=C(Cl)N(C2=O)C([H])([H])C(=O)N([H])C([H])([H])C2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[C@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C([H])C(Cl)=C2[H]
[H]C1=C([H])C([H])=C2C(=C1[H])[C@@]([H])(OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])[C@@]1([H])N(C([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC4=C([H])C([H])=C5C(=C4[H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C6=C(C([H])=C([H])C([H])=C6[H])[C@]54[H])=C([H])C([H])=C13)C([H])([H])C2([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC([H])=C(S1)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])=NC([H])=C2[H])C([H])=C1[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C(OC(F)(F)F)C([H])=C([H])C(N([H])C([H])([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1(C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
CCC[C@H](CO)NC1=NC(S[C@@H](C)C2=CN=CC=C2Cl)=NC2=C1SC(=O)N2
[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(C2=NC(=C3N2C([H])=C([H])N=C3N([H])[H])C2=C(C([H])=C(C([H])=C2[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H]
CN1CCN(CC1)C1=C(C=C(C=C1)C(=O)NC(=O)NCCCCCC(=O)NO)N(O)=O
[H]N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C3=C(C([H])=C([H])C(Cl)=C3[H])N2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C(=N\OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])\C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N1C([H])([H])C2=C(C3=C(S2)N2C(=NN=C2[C@]([H])(N=C3C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C2C(=NN([H])C2=C1[H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1
[H]N(C(=O)[C@]1(C([H])([H])C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(F)=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=N1)S(=O)(=O)C([H])([H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]\C(=N/OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(S1)C([H])=NC([H])=C2SC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
CCNC(=O)C1=CC2=C(NC3=CC=C(OC(F)(F)F)C=C3)N=CN=C2S1
[H]OC(=O)[C@@]([H])(N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C1=C([H])C(OC2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C([H])C(C([H])=C([H])[H])=C1[H]
[H]N1C(=O)C([H])([H])[C@]2(C1=O)C(=O)N(C(=O)C1=C2C([H])=C(Br)C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1F
[H]O\N=C(/[H])C1=C(O[H])C(Cl)=C(C([H])=C1[H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(N=C2C(=O)OC([H])([H])C(F)(F)F)C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])C1=C([H])C(=O)OC2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C12
[H]O[C@@]([H])(C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N1N(C(=O)C(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(C(=NC([H])=N1)C#CC1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=NC(C#CC([H])([H])OC2=C([H])N=C([H])C([H])=C2[H])=C([H])N2N=C(N=C12)C1=C([H])C([H])=C([H])O1
[H]C1=C([H])C([H])=C(C2=NN=C3SC([H])([H])C(=NN23)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(OC([H])([H])C([H])([H])[H])=C1[H]
[H]SC([H])([H])[C@]1(C(=O)N([H])[C@]([H])(C(=O)N([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(OC(=O)C(=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C(=C1[H])[N+]([O-])=O)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C1=C([H])C(=C(Cl)C([H])=C1[H])[N+]([O-])=O
[H]OC([H])([H])[C@@]([H])(N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])=NC([H])=C2[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(OC1([H])[H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C([H])([H])C1(OC([H])([H])[C@]2(O1)C([H])([H])[N@]1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])[C@]1([H])C(=O)N([H])C(=O)[C@](OC2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C(Cl)=C3[H])C([H])=C2[H])(C1=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=N\OC([H])([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(\C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])\C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)N([H])C(N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])=C(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C([H])([H])SC2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])[N+]([O-])=O
COC1=CC(NC(=O)\C=C\C2=CC(O)=C(O)C=C2)=CC=C1
[H]OC(=O)C([H])([H])OC1=C2C(=C([H])C([H])=C1[H])[C@]([H])(C([H])([H])C([H])([H])C([H])([H])OC([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2N(C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(\[H])=C1\C([H])=C([H])C(=O)C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2S1)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C(=O)C2=C(N(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])[C@]([H])(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OS(=O)(=O)C(F)(F)F
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C(=O)N(C(=N2)C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3C([H])([H])SC2=C([H])C([H])=C(Br)C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2O[C@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]S\C(=N\C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C([H])=C3C(C([H])=O)=C([H])N([H])C3=C12
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C([H])([H])C(=O)N2C([H])=C(C(=O)N([H])C2=O)C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])N=C1C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=NC(=NC2=C1C([H])([H])C([H])([H])N(C1=NC([H])=C([H])C([H])=C1C(F)(F)F)C([H])([H])C2([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2OC([H])([H])C([H])([H])C2=C([H])C(=C1[H])C1=NN=C(O1)SC([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)C(F)(F)F
[H]N([H])C1=C(OC2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])N=C(C([H])=C1OC([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)N(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])[C@@]3([H])N(O[C@@]4(C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OS([O-])(=O)=O)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(O[C@]([H])(C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=N[C@]([H])(N(C(=N1)N([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])O1
[H]OC([H])([H])C([H])([H])N1C([H])=C([H])C2=C1C(=NC([H])=N2)N([H])C1=C([H])C(Cl)=C(OC2=C([H])C([H])=C([H])C(=C2[H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[C@@]1([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N([H])C1=C(Cl)C([H])=C(C(SC2=C([H])C([H])=C([H])C([H])=C2C(=O)N(C([H])([H])[H])C([H])([H])[H])=C1[H])[N+]([O-])=O
[H]N(C1=NOC2=C(C([H])=C([H])C([H])=C12)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=N[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])O1
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(=C1C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[H]
CCN1CCC(=C(C1)C(=O)OCCC1=CSC=C1)C1=CC=CC=C1
CC(=O)NC1=NC(C)=NC2=CN(N=C12)C1=CC=CC=C1
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=NC([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(Cl)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)N(C2=C([H])C(OC([H])([H])[H])=NC([H])=N2)C2(C1=O)C([H])([H])C([H])([H])N(C([H])([H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]1([H])C3=C(C(N([H])C(=O)C([H])([H])C([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=C([H])C(=C(N=C2C(=C1[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C(N4C([H])=C([H])C(=C([H])C4=N3)C(F)(F)F)C([H])([H])C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=C([H])C(=NC([H])=C2C([H])=C1C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])N([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C2=C([H])C([H])=C(Cl)C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C1=C([H])C([H])=C2N=NN(C2=N1)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)[C@@]1([H])C([H])([H])[C@@]2(C1([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(=C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=C(C([H])=C4[H])C([H])([H])C4=C([H])C5=C(OC([H])([H])O5)C([H])=C4[H])[C@@]([H])(C([H])([H])[H])C3([H])[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])N1C(=NC(C(=O)N([H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])=C1C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])O[C@@]1([H])O[C@]([H])(C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=C([H])S2)C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])=C1[H]
[H]N(C1=C(C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]2(C([H])=C([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)N(C([H])([H])[H])C([H])([H])[C@@]1([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(=C1[H])C(F)(F)F
[H]N1C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2N2C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@@]12[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C2=C(N=C(N=C2C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C([H])=O)[C@]([H])(C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C([H])=C2C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])[C@]([H])(C([H])=C([H])C2=C([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(OC(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]12[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C(C2=NC(=NO2)C([H])([H])N([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C(N=C1N([H])[H])N([H])[H])C(=O)O[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]1([H])N2C(=O)[C@@]([H])(N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)C([H])([H])N1C2=C([H])N=C(Cl)C([H])=C2C(SC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C([H])N=C12)N([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C([H])C([H])=C(C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3F)C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=C2N(N=C(C2=NC(=N1)C1=C(N([H])[H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(OC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C2=NN([H])N=N2)C(=NC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C([H])=C(SC2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12CC#C
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(C2=C([H])C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])S1)C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C1=C([H])C(=NC2=C(C(=NN12)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1Cl)C([H])([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])[C@@]([H])(OC([H])([H])C1=C(N=C(C#N)C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C1=C(C2=C(N1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])N(C2=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C([H])C(=C([H])C([H])=C2N=C1C([H])([H])[H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])SC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(N=C1C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C3=NC([H])=C([H])C([H])=C3C([H])([H])C([H])([H])C1([H])[H])C([H])=C([H])C([H])=C2[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C#CC2=C(Cl)C([H])=C([H])C(=C2[H])C2=NN(C3=C2C([H])([H])N(C([H])([H])C3([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C([H])([H])[C@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]2(C3=C(C([H])=C([H])C([H])=C3[H])[S@](=O)C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON(C([H])=O)C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C(SC2=C([H])N=C(S2)N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(C(=O)O[H])C([H])([H])[P@@](=O)(O[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@]12C([H])([H])[C@]3(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@](C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])[P@](=O)(O[H])C([H])([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C(=O)O[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])[P@](=O)(O[H])C([H])([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C(=O)O[H])(C3([H])[H])C2([H])[H])C(=O)O[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N1C2=C(C([H])=C(C([H])=C2[H])C2=NOC(=N2)C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C1=C(Cl)C([H])=C(OC([H])([H])C2=C(ON=C2C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C([H])C(=C2C([H])=C1[H])S(=O)(=O)C1=NN(C2=C([H])C([H])=C(C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC2=C(C([H])=C1[H])C([H])=C(I)C([H])=C2C1=C([H])C([H])=C([H])C(N=[N+]=[N-])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])[C@]2([H])C3=C([H])C([H])=C([H])C(=O)N3C([H])([H])[C@]([H])(C1([H])[H])C2([H])[H]
[H]OC1=C([H])C2=C(O[C@@]3([H])C([H])([H])N(C([H])([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])[C@]4([H])C([H])([H])C([H])([H])C([H])([H])[C@]23C4([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C1SC(=C2[H])C1=C([H])SC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(N([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=N1)C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])N1C([H])([H])C([H])([H])[C@@](C2=C([H])C(O[H])=C([H])C([H])=C2[H])(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CCCC1=C(C(=O)OCC)C(C(=O)OCC)=C2N1N=C(C=C2C1=CC=CC=C1)N1CCCC1
[H]OC1=C([H])C(N([H])C2=C(C(=O)N([H])C2=O)C2=C([H])C([H])=C([H])C([H])=C2[N+]([O-])=O)=C([H])C([H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])[C@@]3([H])N(C(=O)C([H])([H])[H])C4=C(C([H])=C([H])C([H])=C4[H])C3([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])N([H])N1[H]
CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OCC2=CC(I)=C(C=C2)N=[N]#N)CC[C@H]1O
[H]C1=C([H])C([H])=C(C(OC2=C([H])C([H])=C([H])C(=C2[H])C2=C3C([H])=C([H])C([H])=C(C3=NC([H])=C2C([H])([H])[H])C(F)(F)F)=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])[H]
COC1=CC=C(NC2=C(C(C)=NN2C2=C(C)C=CC=C2)C2=CC(C)=C(C)C=C2)C(=C1)C(O)=O
[H]N(\C(=N/C#N)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])[C@]([H])(C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]ON(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]N(C(=O)C1=C([H])C2=C(S1)C([H])=C([H])C(Cl)=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(OC1([H])[H])C([H])=C([H])C([H])=C2[H])C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C([H])=C([H])C([H])=C([H])C2=NC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C1=NC([H])=C(C(=N1)N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])[N+]([O-])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N1C(=O)C2=NN(C([H])=C2N=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1\C(=N/C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])N(C2=C([H])C(Cl)=C([H])C([H])=C12)C([H])([H])[H])C1=NN=NN1[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]C1=C([H])N=C(C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=N1)C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=NN(C2=C1C([H])([H])C1=C2C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N1C(SC([H])([H])C([H])([H])C([H])([H])SC2=NC([H])=C([H])N2C([H])([H])[H])=NC(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C2=NOC(=C2C(=O)N(C2=C([H])C(Cl)=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C1([H])[H])[C@]1([H])[C@@]2([H])C([H])([H])[C@@]3([H])C([H])([H])[C@]1([H])C([H])([H])[C@](F)(C3([H])[H])C2([H])[H]
[H]N(C1=NC(=NC2=C1N([H])C([H])([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N2C([H])=NC3=C([H])N=C4N([H])C([H])=C([H])C4=C23)C1([H])[H]
O=S(=O)(CC1CCCCC1)NC1CCN(CC2=CC=C(C=C2)C2=NN=C3N2C2=CC=CN=C2NC2=C3C=CC=C2)CC1
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(\[C@]([H])(N1C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C2N(C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H]
[H]C1=C(OC(=C1[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[N+]1(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(N=C([H])N2C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2I)C(Cl)=N1
[H]N([H])C1=C([H])C(=NC([H])=N1)N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])N([H])C1=C([H])C(N([H])C(=O)C2=C([H])C(=C([H])C(=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(F)(F)F)=C([H])C([H])=C1C([H])([H])[H]
[H]OC1=C2C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])C([H])([H])[H])=C([H])C2=NC2=C1C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H])=C2[H]
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C(F)=C([H])C([H])=C2O\C1=C(\[H])C(=O)C([H])([H])[H]
[H]N1N=C(C2=C(C3=C([H])C(OC(F)(F)F)=C([H])C(=C3N=C12)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C2C([H])=C([H])C([H])=C(C2=C([H])C([H])=C1[H])S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]OC1=C2C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[C@@]([H])(OC([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=NC(=C(S1)C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])[H])N([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)N([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2C(=O)N(C(=O)N([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(C2=C([H])C([H])=NN2C([H])([H])[H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N1C(=C([H])C2=C1[C@@]1(C([H])([H])N([H])C2=O)C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC(=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])N=C1[H]
[H]N([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])N=C(N=C12)N([H])C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])\N=C(/[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2O[C@]([H])(C3=C(C([H])=C([H])C4=C3C(=C([H])C(N4[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=C1OC([H])([H])[H])[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2N=C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C3=C(C([H])=C([H])C(Cl)=C3[H])C2=O)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(SC([H])([H])C([H])([H])[H])=C1[H])C1=C([H])C([H])=C(C2=NN=C(N2C([H])([H])[H])C2(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])N1C(=NC(=C1C(=O)C([H])([H])C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])=C1[H])C([H])([H])N1C(=NC2=C([H])C(OC3([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])C([H])=C12)C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(S1)C1=NN=NN1[H])C([H])([H])S(=O)(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C#N
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(O[H])C(=C([H])C([H])=C1\C([H])=N\N([H])C(=S)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(N2C([H])([H])C([H])([H])N(C([H])([H])C3=C(F)C([H])=C([H])C([H])=C3F)C([H])([H])C2([H])[H])=C2C(=O)N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C(N([H])[H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN=C(O1)C(=O)N([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
CCCCCCNC1=C2C3=CC=C(OC4=CC=C(C=C4)C(C)C)C4=CC=CC(C2=NC1=O)=C34
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC2=C1C([H])=C(N2[H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=O)C(=C([H])OC2=C1O[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC1=C([H])C(OC([H])([H])[H])=C2OC(=NC2=C1Br)C1=C([H])C(F)=C(O[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C(=O)N1[C@]([H])(C2=C([H])C(OC([H])(F)F)=C([H])C([H])=C2OC([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(C2=NC([H])=C(C([H])=C12)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)(C([H])([H])C#C[H])C([H])([H])C#C[H]
[H]N([H])C1=NC2=C(C(SC3=C([H])C(Cl)=C([H])C(Cl)=C3[H])=C(S2)C([H])([H])[H])C(=O)N1[H]
[H]N1C(=C([H])C2=C1C(F)=C([H])C(Cl)=C2[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])C(F)(F)C1=C(Br)C([H])=C2C([H])=C(C#N)C([H])=C([H])C2=C1[H]
[H]N(C1=NC([H])=NC2=C1C([H])=NC(N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H])=C2[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])[C@]2(C(=O)N(C3=C([H])C(F)=C([H])C([H])=C3[H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]OC(=O)[C@]1([H])N(C(=O)[C@@]([H])(S[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])SC1([H])[H]
[H]N([H])C1=NC(=C([H])N2N=C(N=C12)C1=C([H])C([H])=C([H])O1)C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(F)=C2[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NN=C(SC([H])([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)N1C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=NC([H])=C2C([H])=C1[H])[C@@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(C#N)=C2[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C3=C(C(OC([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O[C@]([H])(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=NN2[C@]([H])(C2=C([H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C(C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])=C1C([H])([H])[H]
[H]ON(C([H])=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NN=C(SC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C1=NC2=C(N=C(N2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])C(O[H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C(\[H])=C(/[H])N1C(=NC(=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C(=C(Cl)C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1C(=NC2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])S(=O)(=O)C1=C(OC2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C2N=C(C([H])=C(C2=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1N([H])C(=O)N([H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]\C(=C(\[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])N1C([H])=NC(=C1[H])C([H])([H])[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)C([H])([H])C2([H])[H])C2=C(S1)C([H])=C(O[H])C([H])=C2[H]
[H]OP(=O)(O[H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(\N=C(/S[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C(C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=NC(=O)C1=C(N([H])C([H])([H])[H])C([H])=C(O1)C1=C([H])C([H])=C([H])C(Cl)=C1[H])N([H])[H]
[H]N(C(=O)C([H])([H])N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
O=C(NC1=NC=CS1)[C@H](CC1CCCCC1)N1CCN(CC1=O)S(=O)(=O)CC1=CC=CC=C1
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])[C@@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(OC([H])([H])[H])N=N1)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]1(C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])N(C(=O)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(N([H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]N([H])C1=NC2=C(N=NN2C([H])([H])C2=C([H])C([H])=C([H])O2)C(=N1)C1=C([H])C([H])=C([H])O1
[H]OC(=O)[C@]1(OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C(C([H])=C3Cl)C([H])([H])C(F)(F)F)C([H])=C2C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N1[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(C(=O)C([H])([H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(I)C([H])=C1[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C(Br)=C2C([H])=C([H])C([H])=C([H])C2=C1OC([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(OC(=O)C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1=NC([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]C1=NC(=C([H])C([H])=C1[H])C1=C([H])C(=O)C2=C(O1)C([H])=C([H])C1=C([H])C([H])=C([H])C([H])=C21
[H]N1C2=C(C([H])=C1C1=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C(=O)N(C(=O)N2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])N=C(C([H])=C1[H])N(C1=C([H])C(OC([H])([H])C2([H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC(=C([H])C(=N1)C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
CNC1=NC(NC2=CN(CCOC)N=C2C)=NC=C1C(F)(F)F
[H]N(C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C2=C(S1)N=C([H])C([H])=C2[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(N([H])C2=C(C(=O)N([H])C2=O)C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])=C([H])C([H])=C1Cl
[H]N1C([H])([H])C(=O)N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])[C@@]([H])(C([H])([H])OC([H])([H])C2=C([H])C(=C(Cl)C([H])=C2[H])C(F)(F)F)C1([H])[H]
[H]OC(=O)C1=C([H])C(N([H])C2=C([H])\C(=N/S(=O)(=O)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3C2=O)=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=O)OC([H])([H])[H])[C@@]2([H])S[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(OC([H])([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C3=NC4=C(N3C([H])=C([H])C2=O)C(=O)N(C(=O)N4C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H][C@@]12C[C@]3([H])C[C@@H](CC[C@@]3([H])[C@H](\C=C\C3=CC=C(C=N3)C3=CC=CC=N3)[C@]1([H])[C@@H](C)OC2=O)NC(=O)OCC
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])SC1=NC(=C(N1[H])C1=C([H])C([H])=NC(N([H])[C@]([H])(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C(C([H])=C1[H])N1N=C(OC([H])([H])[H])OC1=O)C([H])([H])[H]
[H]N([H])C1=C(Cl)C([H])=C([H])C(=C1[H])C1=NO[C@@](C(=O)N([H])C2=C([H])C([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])(C([H])([H])N([H])S(=O)(=O)C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=C(N2C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C2N(C([H])([H])[H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3(C2=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1Cl)C1=C([H])C([H])=C(N=C1[H])C(=O)C1=C([H])C([H])=C(F)C(O[H])=C1[H]
C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CS)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)[C@H](CS)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(O)=O
[H]OC(=O)C([H])([H])N1C(=O)[C@@]([H])(N(C(=O)C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C(=O)O[H]
[H]N([H])C1=NC([H])=NC2=C1SC1=NC(=C(C(=C21)C([H])([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H])C1=NN([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(SC(=C2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])OC2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N(C2=C(C(N([H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=C([H])C(=O)C(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C([H])([H])[H])=C([H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC3=C(OC([H])([H])[H])C([H])=C([H])C(=C3[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C2C([H])=C3[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C(C(=O)N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])N1C([H])([H])C(=O)N(C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1C2=C([H])C(Cl)=C(F)C([H])=C2C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C2=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]1(C(=O)N([H])C2=C([H])C(Cl)=C(C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C(N=NN1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])P1(=O)OC([H])([H])C([H])([H])C([H])([H])O1)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C(N([H])C2=C([H])N=C([H])C(Cl)=C2[H])C2=C([H])C(=C([H])C([H])=C2N([H])N1[H])S(=O)(=O)C([H])([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(SC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NN=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])OC([H])([H])[H]
[H]OC(=O)C1=C(C(=O)C2=C(O[H])C([H])=C(C([H])=C2O[H])C(=O)OC([H])([H])[C@@]([H])(N([H])C(=O)C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C(O[H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(\C([H])=C(/[H])C2=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)[C@@]1([H])C2=C(N(C3=C([H])C([H])=C(F)C([H])=C23)C([H])([H])C([H])([H])F)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])O\N=C(\C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C1=C(O[H])C2=C(C([H])=C([H])C(=C2[H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])N(C1=O)C([H])([H])[H]
[H]C1=C([H])C(SC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C(Br)=C1[H]
[H]N(C1=C([H])C([H])=C([H])N2N=C(N=C12)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=NC2=C(C([H])=C1[H])C1=C(O2)C(=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]ON(C(=O)C1=C([H])C([H])=C([H])O1)[C@]([H])(C#CC1=NN(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])[C@]1([H])C2=C(O[C@]3(C([H])([H])[C@]([H])(F)C3([H])[H])C1([H])[H])N=C([H])C(=C2[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C(=O)C([H])([H])N([H])C(=N[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C#CC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C([H])=C(C([H])=C2[H])N2C(=O)C3=C(N=C2C([H])([H])[H])C(=NN3C2=C([H])C3=C(ON=C3N([H])[H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])C1=C(N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N1C2=C(C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(=C1C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])C1=NC2=C([H])C([H])=C(O[H])C([H])=C2S1
[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)C(F)(C2=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])=NN1C([H])([H])[H]
[H]C1=C(C2=NSN=C2OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12C([H])([H])[H]
[H]N1N=C(C([H])=C1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C([H])C([H])=C(C([H])=C2C(C#CC([H])([H])[H])=C1[H])C1=C([H])C(F)=C(O[H])C([H])=C1[H]
[H]N([H])C(=S)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C1(N2C([H])([H])C([H])([H])N(C(=O)[C@@]3([H])C([H])([H])N(C([H])([H])[C@]3([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])N1C2=C(C([H])=C(Br)C([H])=C2[H])C([H])([H])N(C(=O)C([H])([H])[H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C(N=C23)C#CC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N([H])OC([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)C1=C([H])C2=C(OC([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])[C@@]2([H])SC([H])([H])C([H])([H])N([H])C(=O)C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C(Br)=C1[H])C1=C(C([H])=O)C([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]N1C([H])=C([H])C2=C1C([H])=C1C(=C2[H])C([H])([H])[C@]2([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])[C@@]2([H])C([H])([H])[H]
[H]\C(=C1\S\C(=N/C([H])(C([H])([H])[H])C([H])([H])[H])N(C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C(N(C3=C([H])C([H])=C(C([H])=C23)C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C([H])C(=NC([H])=N2)N([H])C2=NC([H])=C(S2)C#N)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C2C(N([H])C([H])=C2S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]N(C(=O)[C@@]1([H])C2=C(OC([H])([H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])=C([H])C(F)=C2[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C2OC(F)(F)C(F)(F)OC2=C1[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=N1)[C@@]([H])(N(C([H])([H])[H])C([H])([H])C1=NC([H])=C3C([H])=C([H])C([H])=C([H])C3=C1C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
COC1=CC=CC=C1C1=NNC(NC(=O)CCCCN2CCCCC2)=C1
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2S(=O)(=O)\N=C2/SC(=C(N2C2([H])C([H])([H])C2([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1[H])C1=NOC2=C([H])C([H])=C([H])C([H])=C12
CCN(CC)C(=O)C1=CC=C2N=C(NC(=O)C3=CC=CC(=C3)C#N)N(CCCOC)C2=C1
[H]C1=NC2=C(C3=C(S2)C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C(=O)N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C(F)(F)F)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(C2=C1C([H])([H])[C@]1(C(=C2[H])C([H])([H])C([H])([H])N(C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])=NC([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(N=C(O2)C2=C([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)C1=C([H])C(=C([H])C(=C1N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(SC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C1=C([H])C(=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])C1=NC(=C([H])S1)C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@]1([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C(C3=C(N2[H])C([H])=C([H])C([H])=C3[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=NC3=C(C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C3[H])C(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2C([H])=C1[H]
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])C([H])([H])OC(=O)[C@]2([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=N1
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(OC3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])N(C3=C(Cl)N=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(S1)C1=NC([H])([H])C([H])([H])N1C(=C2[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)OC([H])([H])[H])[C@]1([H])OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])O[C@]([H])(C1([H])[H])[C@@]([H])(OC1=C(OC([H])([H])[H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC([H])=C(SC([H])([H])C2=C(ON=C2C([H])([H])[H])C([H])([H])[H])S1
[H]N1C(=O)[C@]([H])(N(C(=O)[C@@]1([H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])N=C(C([H])=C1[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[C@](O[H])(C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C2SC([H])=C([H])C2=C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])[H])C([H])=C1[H]
[H]O[C@@]12C(=O)C(=C([H])[C@@]1([H])[C@@]13O[C@]4(O[C@@]([H])([C@]1([H])C([H])=C(C([H])([H])OC(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N([H])[H])C(OC([H])([H])[H])=C1[H])C2([H])[H])[C@@](O4)(C(=C([H])[H])C([H])([H])[H])C([H])([H])[C@@]3([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C3=C(N(C4=C([H])C([H])=C(C([H])=C34)C([H])([H])[H])C([H])([H])[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N1C([H])=C([H])N=C(N([H])C([H])([H])C2=C([H])N=C([H])S2)C1=O)C([H])([H])C([H])([H])[H])C(=O)C([H])([H])SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=NC2=C(N1[H])C(O[H])=C([H])C([H])=C2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2N=C(C([H])=NC2=C1[H])N1C([H])([H])C([H])([H])C2(C(=O)N(C([H])([H])C3=C([H])C(Cl)=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])N=C2C([H])=C([H])C([H])=C(N12)C([H])([H])[H]
[H]N(C(=O)C([H])([H])SC([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2N=C1[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]11C(=O)N(C2=C([H])C([H])=C(O[C@]([H])(C([H])([H])[H])C(F)(F)F)C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=NN1C([H])([H])[H]
[H]N([H])C(=O)C1=C(C(N([H])C(=O)N([H])C2=C([H])C(C#N)=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C1=N\C(=C(\[H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C(=O)N1C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)N(C1=O)C([H])([H])C(=O)N([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([O-])=O
[H]OC(=O)C1=C([H])C(=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])[H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CS(=O)(=O)C1=CC(=CC=C1)N1CCN(CC1)C1=NC=C(S1)C(O)(C(F)(F)F)C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C([H])=C2N([H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C(=C2[H])C(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(F)(F)C1([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])[C@@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON(N=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]C1=NC2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C(=N1)N1C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(S1)C([H])=C(S2)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C(=O)C(OC([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])=C([H])C1=O
[H]N(C1=C2N=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)S1
[H]OC(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C2N=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])N(C(=O)C2=C(SC(=N2)C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(=N1)N1C([H])([H])C([H])([H])N(C(=O)OC2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C1(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])N=C1C1([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H]
[H]N(C(=O)C1=C2N=C(OC2=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])[H])C1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N1C(=O)\C(=C2/SC(=S)N(C2=O)C2=C([H])C([H])=C([H])C(Cl)=C2[H])C2=C([H])C(Br)=C([H])C([H])=C12
[H]OC(=O)[C@@]([H])(OC1=C(C([H])=C2C(=O)N(OC2=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C2=C(N([H])C(=O)C([H])=C2C(F)(F)F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C(=C(F)C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
CC(C)C1=NC=C(S1)[C@]1(O)CC[C@@H](CC1)N1CC(C1)NC(=O)CNC1=NC=NC2=CC=C(C=C12)C(F)(F)F
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N([H])C([H])([H])C1=C([H])C2=C(C([H])=C1[H])[C@]([H])(N([H])C(=O)C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])N([H])C1=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=NC2=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]21[H]
[H]C1=C(C(OC2=C(C(OC([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1Cl)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C(Cl)C(=C2Cl)C([H])([H])OC2=C3N=C(C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[C@]1([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1F)N1C([H])=C([H])C([H])=C([H])C1=O)S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1F
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])[C@]3([H])C([H])([H])[C@]3(C3=C([H])C([H])=C(C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=NC2=C(S1)C(F)=C([H])C([H])=C2F
[H]N([H])C1=NC(=C([H])N2C([H])=C([H])N=C12)C1=C([H])C(N([H])C(=O)N([H])C2=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C2[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[N+]([O-])=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C(=O)N([H])[C@]2(N([H])C(=O)N([H])C3=C([H])C([H])=C([H])C([H])=C23)C1=O
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C12)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1Cl
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1F)N(C([H])([H])C#C[H])C([H])([H])C1=C(C([H])=C2N=C(N=C(O[H])C2=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[S@@](=O)C1=NN([H])N=N1
[H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C(F)=C([H])C([H])=C3[H])=C([H])C([H])=C2O1
CCOC(=O)C1=C(C2CC2)N2N=C(C=C(C2=C1C(=O)OCC)C1=CC=CC=C1)N1CCOCC1
OC(=O)[C@H]1CC[C@@H](CC1)OC[C@@H]1C[C@H](F)CN1C(=O)CC1=CC=C(NC(=O)C2=CNC3=C2C=CC=C3)C(Cl)=C1
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C(=O)N([H])[C@@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N([H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C(Cl)=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C2C(=NC(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C(=O)N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])O[C@]([H])(C([H])([H])N1C(=O)[C@@]3([H])C([H])([H])C([H])=C(Cl)C([H])([H])[C@@]3([H])C1=O)C2([H])[H]
[H]C1=C([H])C([H])=C(C(OC2=C(OC(=C([H])C2=O)C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(O1)C([H])([H])[H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])C2=C([H])N(N=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])=C([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]1([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(Cl)C(=C([H])S1)C([H])([H])N1N=NC([H])=N1)C1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C1=C([H])C2=C([H])C([H])=C(C([H])=C2S1)C([H])([H])N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(O[H])C([H])([H])[C@]([H])(O[H])C(\[H])=C(/[H])C1=C(N=C(N=C1C1=C([H])C([H])=C(F)C([H])=C1[H])N(C1=NOC([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
CN1CCN(CC1)C1=C2C=C(NC2=NC(N)=N1)C1=CC=C(C)C=C1
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C2=NC(SC([H])([H])C(=O)OC([H])([H])[H])=C(C#N)C([H])=C12)C([H])([H])[H]
[H]OC(=O)C1=C(Cl)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(O1)C(\[H])=C1/SC(=S)N(C1=O)C([H])([H])C([H])=C([H])[H]
[H]N([H])C1=NC2=C(O[C@]3([H])C([H])([H])N(C(=O)C4=C([H])C([H])=C5OC([H])([H])OC5=C4[H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N(C(=O)C1=C2C(OC([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])N1C2=C(SC([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]3([H])N(C(=O)[C@@]4([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[C@@]([H])(O[H])C3([H])[H])C([H])([H])C3=C([H])C([H])=C([H])S3)C([H])([H])O[H])C1=O)C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])C3=C(C(=C(OC4([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C4([H])[H])C(=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C2OC1([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=NN=C1SC([H])([H])N1C(=O)C2=C(C([H])=C(OC([H])([H])[H])C([H])=C2S1(=O)=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C(Cl)=C(N([H])C([H])([H])[H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(\C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])[H])=C1/C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C(=C([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N([H])C1=C([H])C(=C(N([H])C(=O)N([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])O[C@@]1([H])C([H])([H])N(C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2F)N2C([H])=C([H])C([H])=C([H])C2=O)C([H])([H])[C@]1([H])N([H])C(=O)C1=C([H])C([H])=C(Cl)S1
[H]OP(=O)(O[H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])SC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2(N([H])C1=O)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[H]
[H]N1C(=O)C([H])([H])[C@]([H])(C2=C([H])C(=C([H])C(=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NOC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H])C([H])([H])OC(=O)C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)[C@]([H])(N(C(=O)[C@@]1([H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(N=C1[H])C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C([H])N1[H])C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(C#N)=C([H])C2=C1C(=C([H])N(C(=O)C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C([H])=C(C([H])=C([H])C2=N1)N(C([H])([H])C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N([H])C([H])([H])[C@]1([H])N(C([H])([H])C2=C(F)C([H])=C(F)C([H])=C2F)C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N1C2=C(C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])=C(F)C([H])=C2[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C([H])([H])C(F)(F)F)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C3C(=C1[H])N(C([H])=C3C([H])([H])C([H])([H])S(=O)(=O)N2C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=NSC(N([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])=C1C#N
[H]OC1([H])C2=C([H])C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C2C2=C1C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C2[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C(=N\OC([H])([H])C([H])=C([H])[H])\C([H])([H])OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)O[H]
[H]N([H])C1=N[C@@](C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])C(=O)C2=NC([H])=C(OC([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])C([H])([H])S1
[H]N(C(=O)C(N([H])C1=C(Cl)C([H])=C(Cl)C([H])=N1)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C(C#N)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C(=C1[H])N(C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OS(=O)(=O)C(F)(F)F)=C([H])C(=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])C2=C([H])C3=C(C([H])=C2[H])N(C(=O)C([H])=C3[H])C([H])([H])[H])=C([H])C(=C1[H])C1(OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C(N=C(O1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C([H])C(=C(Cl)C([H])=C1[H])C1=C([H])C(=C2N=C(N=NC2=C1[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])[H]
COC[C@H](C)OC1=CC(\C=C\C2=CC(F)=CC=C2F)=CC(=C1)C(=O)NC1=NN(C)C=C1
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)[C@@]([H])(N1C(=O)[C@@]([H])(N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C2C(O[C@]([H])(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C2=O)=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])C(=C(/[H])\C(\[H])=C(/[H])C([H])([H])O\N=C(\[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])\C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(OC2=C(N([H])C(=O)C3=NC([H])=C([H])C(=C3[H])C([H])([H])C([H])([H])[H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])=C1C(=O)O[H]
[H]N(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=NC2=C(C([H])=C([H])C(=C2[H])S(=O)(=O)N([H])C([H])([H])C2=C([H])C([H])=C(F)C(F)=C2[H])N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N(C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
CON(C)C[C@@H]1CC[C@@H](CO[C@H]2CC[C@@H](CC2)C(O)=O)N1C(=O)CC1=C(F)C2=C(C=C1)N=C(NC1=CC(F)=CC=C1C)O2
[H]N1C2=C([H])C3=C(C([H])=C2C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1F)C3([H])[H]
[H]N([H])C1=NOC2=C([H])C([H])=C(C([H])=C12)N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])=C([H])N=C1C([H])([H])[H])C(F)(F)F
[H]N([H])C(=O)C1=C([H])N=C(N=C1N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])N([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N([H])C1=NC([H])=C(S1)C([H])([H])[H]
[H]N([H])C1=C(C(=NC(=N1)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])N([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@]([H])(O[H])C([H])([H])[H])C(=O)N([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C(=NN2C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])[C@@]2([H])C([H])([H])[C@@]([H])(N(C(=O)C3=C([H])N(C([H])=N3)C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(OC4([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C3[H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]\C(=C(\[H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(C(=N1)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C2N([H])C([H])=NC2=C1[H]
[H]N(C(=O)C1(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)OC1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C#C[C@]1([H])N(C(=O)C([H])([H])N([H])C2(C([H])([H])[H])C([H])([H])C([H])([H])N(C3=NC([H])=C(C#N)C([H])=C3[H])C([H])([H])C2([H])[H])[C@]([H])(C#N)C([H])([H])C1([H])[H]
[H]OC1=NC2=C(N=C1O[H])C(=C([H])C(Br)=C2[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]1([H])[C@@]([H])(C(=O)O[H])[C@@]([H])(C(=O)N(C([H])([H])C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C(=O)N(C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C([H])([H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C1=NC(=C([H])C([H])=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N1\C(=N/OC([H])([H])C([H])([H])[H])C([H])=N[C@]1([H])C([H])(C([H])([H])[H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])C1=NC([H])=C(S1)C(\[H])=C(/[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC1=C(N([H])C2=C(N([H])[C@@]([H])(C3=C([H])C([H])=C(Cl)O3)C([H])([H])C([H])([H])[H])C(=O)C2=O)C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])N([H])[H])C1=C([H])C([H])=C(C([H])=C1F)C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(F)=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)C1=C([H])C([H])=C(O[C@@]([H])(C([O-])=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(Br)=C(N([H])SC(=S)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
CS(=O)(=O)C1=CC(NC2=NC(=CC=N2)N(CCO)C2=C3OCOC3=CC=C2Cl)=CC=C1
[H]C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C2N=C(C([H])=C2N=C(N1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])N1N=C([H])N=C1[H])C(C#N)(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C(C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N([H])C(=O)N([H])C2=O)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C(=O)N([H])C(=C(C(=O)OC([H])([H])[H])[C@@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(C2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])(C2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C2C(=C1[H])C(=NC2([H])[H])C1=NC2=C(N1[H])C([H])=C([H])C(=C2[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[S@](=O)C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])N=C([H])C([H])=C2[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=N\OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])\C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=O)N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C(=NC2=C1[H])[C@@]([H])(N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])S2)=C([H])C([H])=C1[H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2OS(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
O=C(NC1=CC=CC=N1)N1CCN(CC1)C1=NC(=NS1)C1=CC=CC=C1
[H]OC(=O)C1=C([H])C([H])=C([H])C(=N1)C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(N=C1C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1O2
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C1OC(C1=C([H])C([H])=C([H])C([H])=C1[H])=C(C2=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(O[H])C([H])=C(\C([H])=C(/C#N)C(=O)C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]N(C(=O)[C@]([H])(C1=NN(N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C1[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(N([H])C1=C([H])C([H])=NC([H])=N1)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C(C#N)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])N1C(=NC2=C([H])C([H])=C(C([H])=C12)C(=O)N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N1C2=C(N=C1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=S)N(C(=O)N2C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(N=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]C1=C([H])C([H])=C([H])C(=N1)C(=O)C([H])(Br)Br
[H]N([H])C1=C(SC2=NC([H])=C([H])C([H])=C12)C(=O)N([H])\N=C(/[H])C1=C([H])N=C([H])N1C([H])([H])[H]
[H]N1C2=C(N=C1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N2[H])C([H])([H])C([H])([H])C([H])([H])F
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(=N1)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C(=N1)C1=C([H])C([H])=C([H])C(Cl)=C1C([H])([H])C([H])([H])C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C2C(=N1)N(C(=O)C(I)=C2C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=NN(C(=O)C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C4N([H])C([H])=C([H])C4=C3C([H])([H])C([H])=C([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]O[C@]1(C([H])([H])N([H])C(=O)C2=NN([H])C(=N2)N([H])[H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C([H])(N1N=C([H])N=C1[H])C1=C([H])C(OS(=O)(=O)N([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])SC2=C([H])C(O[H])=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(S1)N([H])C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C1=NC(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)C1=NN=C(O1)C(C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C(=C1[H])C(F)(F)F)[C@]1([H])C(=O)N(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])[C@]2([H])N(C3=NC4=C(S3)C([H])=C(OC([H])([H])[H])C([H])=C4[H])C(=O)[C@@]([H])(C([H])([H])[H])[C@@]12[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2N([H])C(=NC2=NC(=N1)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]C1=C([H])[C@]2([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])[C@@]([H])(OC1=C(C(OC3=C([H])C([H])=C([H])N=C3C([H])([H])[H])=NC([H])=N1)C([H])([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N2C(=NC3=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C3C2=O)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]O[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1C([H])([H])C1=C([H])N=C([H])C(=C1[H])C([O-])=O
[H]N=C(N([H])[H])N([H])\N=C(\C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
CC(C)(C)C1=CC=C(CC(=O)N2CCC3(CC2)CCN(CCC2=CC=CN=C2)C2=C(O3)C=CC=C2)C=C1
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])O[P@](=O)(O[H])OC3=C([H])C4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)OC([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C(Br)C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])[C@@]1([H])C(=O)N([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])N=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C2=C1N([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N([H])C1=NC([H])=C(N=C1C(=O)N([H])C([H])([H])[H])C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])[C@@]([H])(C(=O)N([H])[C@]([H])(C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(O[H])C([H])([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)[C@@]([H])(C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C2=C(C([H])=C([H])C([H])=C2[H])[S@](=O)C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N([H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1=O)[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
CC1=C(CCOCCCO[N+]([O-])=O)C=C(N1C1=CC(F)=CC=C1)C1=CC=C(C=C1)S(C)(=O)=O
[H]OC1=C([H])C([H])=C([H])C(O[H])=C1C1=C([H])C([H])=C(C#N)C(=C1[H])C(F)(F)F
[H]C1=C(C(N2C3=NC(=C(N3C([H])([H])C([H])([H])C2([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(F)(F)F)C(F)(F)F)=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=O)N(C1=C(F)C([H])=C2N=C(OC3=C(C([H])=C([H])C(F)=C3[H])C([H])([H])[H])C3=C([H])N=C([H])N3C2=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]C1=NN(N=N1)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N1C([H])([H])[C@]([H])(OC2=NC([H])=C([H])C(C#N)=C2[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
Cl.CCCCN1CCC2=C(CC3=CC=CC=C23)C1
[H]C([H])([H])[C@@]1([H])C(=O)N(C([H])([H])C#CC([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
COC1=CC=C(C=C1)C(=O)NC1=NC(=NC2=CN(N=C12)C1=CC=CC=C1)C1=CC=CC=C1
[H]C1=C([H])C(=C([H])C([H])=C1F)[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)C([H])([H])C([H])([H])[H]
[H]N(C1=N\C(=C(\[H])C2=C([H])N([H])C3=NC([H])=C([H])C([H])=C23)C(=O)N1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=O)\C(S1)=C(/[H])C1=C([H])C2=C(N=C([H])C([H])=C2[H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C2=C([H])C([H])=C([H])C(=C2N=C1Cl)C([H])([H])[H])C(=O)C1=C([H])C([H])=C(Br)S1
[H]OC1=C([H])C(\C([H])=C(\[H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1F)N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=NC(=C([H])S1)C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])N(C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])=C12)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(C(=O)C([H])([H])S(=O)(=O)C([H])([H])C1=C(OC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=NN=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])[C@](C3=C([H])C(O[H])=C([H])C([H])=C3[H])(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[S@@](=O)C2([H])[H]
[H]N([H])N([H])C(=O)C([H])([H])SC1=NC2=C(C(=C([H])S2)C2=C([H])C([H])=C([H])C(F)=C2[H])C(=O)N1C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]OC(=O)C1=NC(=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]([H])(C1=NC([H])=C(N1[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C([H])C(=N1)C([H])([H])SC1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]C1=C(N=NN1C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@@]([H])(OC1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]O\C(=N\C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])N2C(=NC3=C(C([H])=C(C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C(=O)N([H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C(N=C1C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])=C2[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])[C@@]2([H])C3=NC([H])=C(Br)C([H])=C3C([H])([H])C([H])([H])C3=C2C(Br)=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])SC([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N([H])C1=NC([H])=C(Br)N=C1OC([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(OC(=C2[H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])S(=O)(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=NOC(=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=NN=C(N1C([H])([H])[H])C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]C1=C(SC(=N1)[C@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
[H]C1=NC(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C1=NC2=C([H])C(OC([H])([H])[H])=C([H])C(=C2C(=O)O1)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])N(C([H])([H])[H])S(=O)(=O)C1=C2C([H])=C([H])C([H])=C(N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@](C#CC1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])N=C([H])N1C([H])([H])[H])C1=C([H])C([H])=C(C#N)C(=C1[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N1C2=C(C([H])=C(Br)C([H])=C2[H])C2=C1C1=C(N([H])C(=O)C2([H])[H])C([H])=C([H])S1
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1N=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(C(=O)N([H])C3=C([H])C([H])=C4C(=C3[H])C3=C(C(=NN3C3=C([H])C([H])=C(F)C([H])=C3[H])C(=O)N([H])[H])C([H])([H])C4([H])[H])=C(Cl)C([H])=N2)C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(N=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1S2)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])[C@@]([H])(O[H])C([H])([H])N2[H])=C([H])C(O[H])=C1[H])C1=C([H])C(Cl)=C([H])C(I)=C1O[H]
OC(=O)C1=CC=CC=C1N1CCN(CC1)C1=NC=C(S1)C(O)(C(F)(F)F)C(F)(F)F
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])[C@]([H])(C1=NC(=C([H])O1)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(Cl)=C([H])C([H])=C1[H])S(=O)(=O)C1=C(SC(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]O\N=C(\C1=C(F)C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])=C1[H])C([H])([H])[H]
[H]\C(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])=C1\C([H])([H])N2[C@]3([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C3([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])SC1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]OC([H])([H])[C@@]1([H])OC(=O)\C(=C(/N([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O
[H]N(C([H])([H])C1=NC([H])=C([H])S1)[C@]([H])(C([H])([H])[H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1F)C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]N([H])C(=O)C1=C2N([H])C3=C(C([H])=C(F)C([H])=C3[H])C2=C(N=C1[H])N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])S(=O)(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)P(=O)(O[H])O[H]
[H]N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C([H])C([H])=C(C([H])=C3N=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C2=NN(N=N2)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(SC([H])=C2C2=C([H])C(Cl)=C(F)C([H])=C2[H])=C(Br)C([H])=N1
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1(N([H])C(=O)C(F)(F)F)C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C(Cl)=C([H])C([H])=C1C1=NC(=NO1)C([H])([H])[H])C([H])([H])[H]
[H]\C(=N/N1C([H])=NC2=C(C(=C([H])S2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])S1)S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)C(C2=C([H])N=C3C([H])=C([H])C([H])=C([H])N23)=C(C1=O)C1=C([H])N2C3=C(C([H])=C([H])C([H])=C13)C([H])([H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)[C@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C([H])=C2N=C([H])SC2=C1[H]
[H]N(C(=O)C1=C(C2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N(C2=C([H])C(=C([H])C([H])=C2C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C2C(=NC(=N1)N([H])[H])N([H])C(=C2SC1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C(OC(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])N=C(C(OC2([H])C([H])([H])N(C3=NC4=C(C([H])=C([H])C([H])=C4[H])C3([H])[H])C2([H])[H])=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(C2=C3N=C(C([H])=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1Cl)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)[C@]1([H])C([H])([H])N(C2=C([H])N=C([H])C(=N2)C#N)C([H])([H])C1([H])[H]
[H]N(C1=NC2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C2N2C([H])=NC([H])=C12)C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C(N([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])=C2[H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(S1)C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=NON=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NOC3=C2C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[H])C([H])([H])SC(C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C(C#N)C([H])=C([H])C(N([H])C([H])([H])C(F)(F)C2=NC([H])=C([H])C([H])=C2[H])=[N+]1[O-])C([H])([H])C1=C(F)C([H])=C([H])C([H])=N1
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C(S1)C1=NN=C2S\C(=C(\[H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C(=NN12)C1=C([H])C(F)=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])[H])=C(C([H])=N1)C(F)(F)F)C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])N1C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C([H])=N3)C([H])([H])C2([H])[H])=NC2=C(C(=C(S2)C([H])([H])[H])C([H])([H])[H])C1=O
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C2=NC(=C([H])C([H])=N2)C2=C([H])C([H])=C([H])C(N([H])[H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C2=NC(=C([H])C([H])=C12)C([H])([H])[H])C1=C([H])C(SC([H])([H])C([H])([H])[H])=C([H])C(C#N)=C1[H]
[H]OC(=O)[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3(C(=C([H])C(=O)[C@]4([H])[C@@]5(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]5([H])C([H])([H])C([H])([H])[C@@]34C([H])([H])[H])[C@]2([H])C1([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C(=O)C1=C([H])C([H])=C(O1)C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]O[C@]1([H])[C@]([H])(O[H])[C@@]2(C(=O)N([H])C([H])([H])[H])C([H])([H])[C@]2([H])[C@@]1([H])N1C([H])=NC2=C1N=C(N=C2N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C#CC([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H]
OC1=CC(O)=C2C(=O)C=C(OC2=C1)C1=CC=C(I)C=C1
[H]N([H])C1=NC(=C([H])C2=C1C([H])=NC1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C21)C1=C([H])C(OC([H])([H])[C@]([H])(N([H])[H])C([H])([H])C([H])([H])[H])=C([H])N=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
CCN1CCC(C2=CC=CC=C2)=C(C1)C(=O)OCCC1=CC=C(Cl)C=C1
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C([H])([H])C3=C([H])N([H])C4=C3C([H])=C([H])C([H])=C4[H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C1(F)C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)S(=O)(=O)C(F)(F)F
[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=NC([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@]([H])([N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=NC(=NN2C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])OC([H])([H])[C@](N([H])[H])(C(=O)N([H])C1=C([H])C(C(=O)OC([H])([H])[H])=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C(\N=N\C2=C(O[H])N(N=C2C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(O[H])=C1[H]
[H]N(C1=C(C([H])=NC2=C1C([H])=NN2C([H])([H])C([H])([H])C([H])([H])[H])C(=O)OC([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=NC([H])=C([H])S1)C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C(Cl)C([H])=C1N1C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2C(F)(F)F)C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N1C([H])([H])[C@]2([H])[C@@]([H])(C([H])([H])OC([H])(C([H])([H])[H])C([H])([H])[H])[C@]2(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])[C@]2([S@@](=O)C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(OC3=C([H])C([H])=C(C([H])=C23)C(F)(F)F)C(=N1)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(\C([H])=C1/C(=O)N([H])C(=O)C2=C([H])C([H])=C(C#CC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])S1)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C3=C(C([H])=NN3C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])[C@]12C([H])([H])[H]
[H]N(C1=NN2C(=C([H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])=N1)C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C(/[H])C2=NC3=C(N2C([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]OC1=C(\N=N\C2=C(O[H])C([H])=C(C3=C2C([H])=C([H])C([H])=C3[H])S(=O)(=O)O[H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C#N)N1C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(C2=NN3C([H])=C([H])N=C3C(=N2)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])N1SC2=C(F)C([H])=C([H])C([H])=C2C1=O
[H]C1=C([H])N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])N1C([H])=NC([H])=C1[H]
[H]C1=C([H])C2=C(O1)C([H])([H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])[C@@]2([H])C([H])([H])N1C([H])([H])C([H])=C([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=NC([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])N2C(=O)N(N=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NN(C2=C([H])C([H])=C(C([H])=C12)N1C([H])=C([H])C(=C([H])C1=O)C1=C([H])C([H])=C(Cl)C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C(N2C([H])=C([H])C([H])=C([H])C2=N1)C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C1[H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]C1=C2OC3=C(N=C(OC([H])([H])[H])N=C3N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C2=C([H])C(Cl)=C1[H]
[H]C1=C(C([H])=C(SC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=C1[H])C(F)(F)F)C1=NN(C2=C1C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C([H])([H])C1=NC2=C(N1[H])C([H])=C(Cl)C([H])=C2Cl
[H]N=C(N([H])[H])N1N=C(C([H])=C1[H])C([H])([H])[H]
[H]N(\C([H])=C1/C(=O)N([H])C(=O)C2=C([H])C([H])=C(C([H])=C12)C1=C([H])OC([H])=C1[H])C1=C([H])N=C(C([H])=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C([H])=C([H])C([H])=C1\C([H])=C1/C(=O)N([H])C2=C1C([H])=C(C([H])=C2[H])C(=O)C1=C([H])C([H])=C([H])S1
[H]N1N=C([H])C2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C([H])C([H])=C12)C(=O)C1=C(F)C([H])=C(C([H])=C1F)C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1Br)C1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1([H])[H])C1=C3C([H])([H])C([H])([H])C2=NN(C([H])=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H])C1=C(F)C([H])=NC(=N1)N([H])[C@]([H])(C1=NC([H])=C(F)C([H])=N1)C([H])([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C(\C([H])=C(/[H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC(=C(O1)C1=C([H])C2=C(N=NN2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C(N=C(C(OC([H])([H])[H])=N1)C1=C(OC([H])([H])[H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])N=C([H])N=C1N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC([H])=C([H])S1)[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N1C([H])=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C1=O)C([H])([H])C([H])([H])[H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])=C(C(=O)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12