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[H]C1=NC([H])=C2C(=C1[H])C(=O)N(N=C2C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC(=O)C1=C([H])C([H])=C([H])C(O[H])=C1C(=O)C1=C(O[H])C([H])=C(C([H])=C1O[H])C(=O)O[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(O[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C([H])O1)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OP(=O)(O[H])[C@]([H])(C(=O)N([H])C(\[H])=C(/[H])C1=C([H])C([H])=C(F)C(F)=C1[H])C1=C([H])SC2=C1C([H])=C(Cl)C([H])=C2[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])[C@]1(C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C2([H])N(C([H])(C3=C(Cl)C([H])=C([H])C([H])=C3[H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])[C@@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])[C@]2([H])C([H])([H])N(C(=O)C3=C(C([H])=C(OC([H])([H])[H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N=C(S2)N([H])C2=NC(=C([H])C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]C1=C(OC2=C([H])C([H])=NC([H])=C12)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(Cl)C([H])=C2[H]
[H]N(C1=NN=C2C([H])=C([H])C(=C([H])N12)C1=C(N=C([H])O1)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC2=C(C([H])=NC([H])=C2[H])N1C1([H])C([H])([H])C([H])([H])N(C(=O)N([H])[C@]2([H])N=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C(C([H])=C([H])C([H])=C3[H])N(C2=O)C([H])([H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC1=C([H])C(I)=C(C([H])=C1OC([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C(=NC([H])=C1C([H])([H])[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C2N([H])C([H])=NC2=C1[H]
[H]O[C@@]([H])(C([H])([H])N(C1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC(F)(F)C([H])(F)F)=C1[H])C(F)(F)F
[H]C1=C([H])C2=C(S1)C([H])([H])[C@]([H])(OC([H])([H])[H])O[C@]21C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
CCCCN1C(=O)C(=O)C2=CC(=CC=C12)S(=O)(=O)N1CCC[C@H]1CCOC
[H]\C(=C(\[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2N=C1Cl)C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(O1)C([H])=C([H])C(=C2[H])C([H])([H])[H]
[H]C1=NC2=C(C(=NO2)C([H])([H])[H])C(SC2=C([H])C([H])=C([H])C([H])=C2Cl)=N1
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(N=N1)C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])N=C(C([H])=C2[H])C([H])([H])OC([H])([H])[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC([H])([H])C([H])([H])N1N=NN=C1[C@]([H])(N([H])C(=O)C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N(C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C12)C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C#CC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[S@@](=O)C([H])([H])[H]
[H]OC(=O)[C@]1([H])N(C(=O)C([H])([H])SC([H])([H])C(=O)[C@@]([H])(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NN2C([H])=C(C3=NC(=NO3)C([H])([H])[H])C(=C12)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(N=C1[H])N([H])C(=C2[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(S[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=NC(=C1[H])C1=NN=C(S1)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])OC2=C([H])C(=C([H])C([H])=C2N(C1=O)C([H])([H])[H])N(C(=O)C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C(S1)C([H])=C([H])C(=N2)C1=C([H])C([H])=C(OC([H])([H])C2=C(ON=C2C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC2=C(S1)C([H])=C(Br)C([H])=C2[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=C(C([H])=C(OC1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])O[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC2=C([H])N=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(F)=C1[H])C1=NC([H])=C(N([H])C2=NC([H])=NC3=C2N([H])C([H])([H])C2=C(O3)C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])=N1
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])[C@]([H])(C([H])([H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(C(=O)C([H])([H])[H])C(=O)C2=C(Cl)C([H])=C([H])C(Br)=C2N1[H]
[H]N([H])C(\SC1=C(F)C([H])=C([H])C([H])=C1[H])=C(\C#N)/C(/C#N)=C(/SC1=C(F)C([H])=C([H])C([H])=C1[H])N([H])[H]
CCCNC1=CN=C2N([C@@H](C[C@@]2(C)CC)C(=O)NCC2=CC=C(C=C2)C(N)=N)C1=O
[H]OC1=C2O[C@@]3([H])C4=C(C5=C(N4[H])C([H])=C([H])C(=C5[H])C([H])([H])C([H])([H])\N=C(/N([H])[H])N([H])C([H])([H])C4=C([H])C([H])=C(N([H])[H])C([H])=C4[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2N2C([H])=NC([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])[H]
[H]N1C2=C(N=C1C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=N1)C([H])=C(C([H])=N2)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C(Cl)C([H])=C(O[H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])N(C2=C([H])C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C3([H])[H])C2=C(C([H])=NC(=N2)N([H])C2=C([H])C(=C([H])C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=O
[H]N([H])C1=NC([H])=C(C(=N1)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(N([H])C(=N1)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(\[H])=C(\C(\[H])=C(/[H])\C(\[H])=C(/C1=C([H])C(=C([H])C(=C1OC([H])([H])C([H])(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])S1)C([H])([H])[H])/C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(Cl)=NC2=C([H])C([H])=NN12
[H]C1=C([H])N(C(=C1[H])C(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)S(=O)(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C1=NC2=C(SC(=C2[H])C2=C([H])N([H])N=C2[H])N2C1=NC([H])=C2C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]2([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])[C@]([H])(N([H])C1=O)C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])N([H])C(=O)C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C(Br)=C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(=NC2=C(O[H])C([H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]C([H])=C([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])S1
[H]N([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC(=O)C1=C(C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C2=NSN=C2C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)C1=C(C(=O)C2=C([H])C([H])=C([H])C([H])=C2N1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(=O)N([H])C1=C(C(=O)O[H])C2=C(S1)C([H])([H])N(C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C1=C(Cl)C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=NC(OC([H])([H])[H])=C([H])C([H])=C1N1C(=NN=C1C([H])([H])[H])C1=NC([H])=C(OC2=C(C([H])=C(F)C([H])=C2[H])C([H])([H])[H])N=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N2C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=NN2C([H])=C([H])C(=C12)C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)OC([H])([H])[H]
[H]C1=C(N=C(S1)C1=NOC(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=N1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N1[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(C(=O)OC([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]N(C1=C([H])C([H])=C(F)C(Cl)=C1[H])C1=C2C([H])=C(N([H])C([H])([H])C3=C([H])N(N=N3)C3=C([H])C([H])=NC([H])=C3[H])C([H])=C(Cl)C2=NC([H])=C1C#N
[H]N([H])C1=N[C@@](C2=C(F)C([H])=C([H])C(=C2[H])C([H])([H])C(=O)C([H])([H])SC2=C([H])C(=NC(=N2)N([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])S1
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C(=C(O[C@]2([H])C([H])([H])[C@@]3([H])N(C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C(C#N)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C1(C2([H])[H])C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(Br)=C(OC2=C([H])C([H])=C(O[H])C(=C2[H])C(=O)N([H])C([H])([H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C(Br)=C1[H]
[H]N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C#N)C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C(\[H])C1=C([H])C([H])=C([H])S1)C1=C(Cl)C(=O)N([H])N=C1[H]
[H]OC(=O)C1=C([H])C(N([H])C2=C(C(=O)N([H])C2=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C(=O)N1C2=C(SC([H])([H])C([H])([H])C1([H])[H])C(=O)N(N=C2[H])C([H])([H])[H]
[H]OC1(C([H])([H])N([H])C(=O)C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])N(C([H])=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C(O[C@]2([H])C([H])([H])[C@@]3([H])N(C([H])([H])C([H])([H])[C@]4([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C4([H])[H])[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C([H])C([H])=C1[H]
[H]C1=NOC(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C(SC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(SC(=O)C([H])([H])[H])C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C1=C23
[H]OC1=C(C([H])=C(\C([H])=C2\C(=O)OC([H])([H])C2([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(N=C(N=C2N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C(OC(=O)C([H])([H])[H])=C2[H])C2=C1N=C([H])C([H])=C2[H]
[H]C([H])([H])N(N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C(C#N)(C#N)C1(C#N)C#N)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(C([H])=NC2=C(C([H])=C([H])C([H])=C12)C(F)(F)F)C([H])([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])[N+]([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(OC2([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(N([H])C(=N[H])N([H])[H])=C([H])C([H])=C2[H])C(F)=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)O[H])C1=C([H])C(C2=NC3=C([H])C(=C([H])C([H])=C3N2[H])C(=N[H])N([H])[H])=C(O[H])C(=C1[H])C1=C(N([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
N#C[Cu-]#N
[H]N(C(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])[C@]([H])(F)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N([H])C(=O)C([H])([H])[C@@]1([H])ON=C(C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=NC([H])=C([H])C([H])=C2N1S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1Cl
[H]N(C(=O)C1=C([H])C([H])=C([H])N=C1OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N(C1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1=NC([H])=C([H])N1[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C#CC1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])C([H])([H])C1=C(N=C(N=C1[H])N([H])[H])N([H])[H]
[H]ON(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])N1[H])C1=C(C([H])=NC(=N1)N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N1N=C(C(=O)OC([H])([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC1=C([H])C([H])=C([H])C2=C(OC(=O)C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C12
[H]N(C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C1OC1=NC([H])=C(C([H])=C1Cl)C(F)(F)F)S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@](=O)(O[H])O[P@](=O)(O[H])C(F)(F)P(=O)(O[H])O[H])[C@@]1([H])O[H])N1C([H])=C([H])C(=O)N(C1=O)C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C([H])C2=C([H])C(C3=NC([H])=NC([H])=C3[H])=C(N=C12)C1=C([H])C([H])=C([H])O1
[H]OC1=NC(=NC2=C1N=C(C([H])([H])C1=C([H])C([H])=C([H])O1)C2([H])[H])N([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N([H])C1=C2C(=NC3=C1[C@]([H])(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C(C(=O)OC([H])([H])C([H])([H])[H])=C(N3[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)[C@@](OC2([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC(=C1C(=O)OC([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])[C@]([H])(OC([H])([H])C1=C([H])N(C(=O)C([H])=C1C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(N([H])N=C2C(=O)OC(OC2=O)(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C1=NC(=C(O1)C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C2C([H])=C(C(=O)OC([H])([H])[H])C(=O)OC2=C1[H]
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CCCCN1C2=NC3=C(N2C=C1C1=CC=C(F)C=C1C)C(=O)NC(=O)N3C
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[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C(C#N)C(=C1[H])C(F)(F)F
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CC(C)N1CCN(CC1)C(=O)C1=C2NC=C(CN3CCOCC3)C2=CC=C1
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[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(Cl)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C([H])C3=C(C([H])=C2N1[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@]1([H])C([H])([H])N(C2=NC3=C(N2C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C3=O)C([H])([H])C([H])([H])C1([H])[H]
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[H]N1C2=NC([H])=C([H])C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C3=C([H])C(Cl)=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C(Cl)=C2[H]
[H]N1[C@]2([H])C([H])=C(C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(=C([H])[H])C([H])([H])[H])C1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(C1=C([H])C2=C(C([H])=C1[H])N(C([H])([H])C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])(C(F)(F)F)C(F)(F)F
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(\C(SC([H])([H])C1=C([H])SC2=NC([H])([H])C([H])([H])N12)=N\C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(\C([H])=C(/[H])C2=C(Cl)C([H])=C(OC([H])([H])C3=C(ON=C3C([H])([H])OC3=C(Cl)C([H])=C([H])C([H])=C3F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])=C1[H]
[H]N([H])C(=NC(=O)[C@]1([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1(C([H])([H])[H])C([H])([H])[H])N([H])[H]
[H]N(C1=NC([H])=NC2=C1SC(=C2[H])N(N1C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(N([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C2=C([H])C(=C([H])C(C3=C([H])C4=C(N([H])[H])N([H])C([H])=C([H])C4=N3)=C2O[H])C(C(=O)O[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])N4C([H])=C([H])C([H])=C([H])C4=N3)=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2(O[H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])N=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C(=C2[H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C(=O)N([H])C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C(=O)OC([H])([H])[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C(=O)OC([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC(=O)N([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)C1=NN(C(=O)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])SC1=NC(=C([H])C(=O)N1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1N([H])C1=C(N([H])[C@@]([H])(C2=C([H])C([H])=C(F)C(=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)C1=O)C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)C1(C(=O)OC([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC([H])([H])C([H])([H])N1N=NN=C1[C@]([H])(N([H])C(=O)C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NN=C2SC(=NN12)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1Cl
[H]O[C@@]([H])(C([H])([H])N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(Br)C([H])=C(\C([H])=C2/C(=O)N([H])C3=C([H])C([H])=C(C([H])=C23)C(=O)OC([H])([H])[H])C([H])=C1Br
[H]OC1=C(O[H])C([H])=C(\C([H])=C(/[H])C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])N=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)N2N=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C1=C(N2N=NC3=C2N=C(N=C3N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C(Br)=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=N2)=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]C([H])([H])OC(=O)[C@]1([H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])[H])C(=O)[C@@]2([H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])C([H])([H])[C@]21C([H])([H])[H]
[H]N([H])C1=NC2=C(C(=O)C3=C([H])C([H])=C(C([H])=C23)C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C(F)=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C(=O)N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])=C4N(C(=O)C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])[H])[C@]([H])(N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C2=C3N(C([H])=C2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])S(=O)(=O)N(C3=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])N(N=N1)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])[C@@]1([H])C([H])([H])SC3=C(C([H])=C([H])C([H])=C3[H])[C@]21[H]
NC(=O)C1=CC2=NC=NC(N3CCN(CCN4CCCC4)CC3)=C2S1
[H]N(C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])N1C(=O)C([H])([H])C2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=O
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(SC3=C([H])C([H])=C(Cl)C([H])=C3[H])C3=C(C([H])=C(F)C([H])=C3N2C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)N3C([H])=C([H])C([H])=C([H])C3=C(C2=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])[H])C(I)=C1[H]
[H]ON([H])C(=O)C([H])([H])[C@@]1(N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=NC(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C2C([H])=NC([H])=C([H])C2=C([H])C([H])=C1[H])C1=NC([H])=C(S1)C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=NC(=C(C2=C([H])C([H])=C3N([H])C(=NC3=C12)N([H])C1=C(Br)C([H])=C(Br)C([H])=C1Br)C([H])([H])[H])C([H])([H])[H]
[H]N1N=NN=C1C1=NN([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C(=N1)N([H])[C@]1([H])C([H])([H])N([H])[C@]([H])(C(=O)OC([H])([H])[H])C1([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C1=NC(=NC([H])=C1C1=NN=C(O1)C1([H])C([H])([H])C1([H])[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C([H])([H])C(=C(/[H])F)\C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(=O)N(C1=O)C1=C([H])C([H])=C([H])C(I)=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[S@@](=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N(C(=O)[C@]([H])(N(C(=O)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C2=C(N=C([H])C([H])=C2[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C([H])=C(N([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C([H])=NC2=N1
[H]OC1=C(N([H])C2=C(N([H])[C@@]([H])(C3=C([H])C(=C([H])O3)C([H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)C([H])([H])[H])C(=O)C2=O)C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NOC(=N2)C([H])([H])OC2=C([H])C([H])=C(F)C(F)=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C(=O)C3=NC4=C([H])C([H])=C([H])C([H])=C4N3C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])N(C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(OC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2=C(OC([H])([H])[H])C([H])=C([H])C3=C([H])C4=[N+](C([H])=C23)C([H])([H])C([H])([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C42)C([H])=C1[H]
[H]N(C1=C(C(OC([H])([H])C([H])([H])OC2=NC([H])=C(Br)C([H])=N2)=NC([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])N=C([H])N1C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])=C(C#N)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2F)C([H])([H])C2=NC([H])=C(S2)C2=C([H])C([H])=C([H])O2)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C2=C(C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(O[H])C([H])=C([H])C(N([H])C([H])([H])C2=C(O[H])C([H])=C([H])C(O[H])=C2[H])=C1[H]
[H]N(C1=NC([H])=C2C([H])=C([H])C(=O)N(C2=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C2S[C@]([H])(C([H])([H])[H])C([H])([H])C3=C2C(=C([H])C([H])=C3OC([H])([H])C2=C([H])C([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C1([H])C([H])([H])C2([H])N(C([H])([H])[H])C([H])(C([H])([H])C2([H])[H])C1([H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C2=C(SC(OC([H])([H])[H])=C2[H])C(=O)N(C1=O)C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C2=C(C(=O)[C@@](C3=C([H])C([H])=C([H])C([H])=C3[H])(C([H])([H])[H])C2([H])[H])C(Cl)=C1Cl
[H]C#CC(=O)N([H])C1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N([H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])N(C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])=C12)C([H])([H])[H])S(=O)(=O)C1=C([H])C(F)=C(F)C([H])=C1F
[H]N1N=NN=C1C1=NN([H])C2=C1C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1Cl)C2([H])[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])C(=O)N1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F)S(=O)(=O)C([H])([H])C1=C([H])C(=C(C([H])=C1[H])N1C(=O)C2=C(OC([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])N=C3C(OC([H])([H])C([H])([H])[H])=C2C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(S2)C(\[H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(N([H])C2=NC3=C(N=C([H])N3[H])C(=N2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]ON(C([H])=O)[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])S1)C([H])([H])N1C(=O)N(C([H])([H])[H])C(C1=O)(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C2=NC([H])=N1)C1=C([H])C(F)=C([H])C(=C1[H])C(F)(F)F
[H]N(C([H])([H])[H])[C@@]1([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2[H])N2C([H])=C([H])C3=C(SC(=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C2=O)C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])[H])C([H])([H])N(C2=C([H])C3=C(N2C([H])([H])C2=C(Cl)C([H])=C([H])C(F)=C2[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C(C#N)C([H])=C2S1
[H]C1=C([H])[C@]2([H])C([H])([H])[C@@]1([H])[C@@]1([H])C(=O)N(C(=O)[C@@]21[H])C1=C([H])C([H])=C(C(=C1[H])C(F)(F)F)[N+]([O-])=O
[H]N1C2=C(SC3=C2C2=C(N=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])=C3[H])C(=O)N([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2S1)C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=C1[H]
[H]C1=C([H])C(C#N)=C([H])C([H])=C1OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N(C1=C(Cl)C(=C(Cl)C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])N2C(Br)=C(N=C12)C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C([H])([H])N1[C@@]2([H])C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C2([H])[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])S[H])[C@]([H])(OC(=O)C1=C([H])SC(=N1)[C@@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H])C([H])([H])S[H]
[H]N(C(=O)C([H])([H])[S@](=O)C([H])([H])C1=C(OC(=N1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(O[H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC1=C(C(=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N(C(=O)O[C@@]2([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C([H])([H])N1C(=S)S\C(=C(\[H])C2=NOC(=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C1=O
[H]N(C1=NC([H])=NN2C([H])=C([H])C(=C12)C([H])([H])OC([H])([H])C(=O)OC([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]C1=C([H])C2=NC(=C([H])C([H])=C2C(=C1[H])C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])[C@@]3([H])C([H])([H])[C@@]3(C3=C([H])C([H])=C(C#N)C([H])=C3[H])C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N1C([H])=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C1=O)C([H])([H])C([H])([H])[H])C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[H]
[H]C1=C(Br)C(Br)=C(S1)C(=O)C([H])([H])Cl
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C(SC2=C([H])C([H])=C(Cl)C([H])=C2[H])=NN(C1=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@@]1([H])C(=O)N([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]\C(=C(\[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]\C(=C(/[H])C1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(C([H])([H])[H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(C1=C([H])C2=C3C([H])=C(C([H])=C([H])C3=C3N([H])C(=NC3=C2C([H])=C1[H])C1=C(F)C([H])=C([H])C([H])=C1Cl)C(O[H])(C(F)(F)F)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C([H])([H])[H])C(=O)C1=NOC(=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C2=C(OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C(N=C12)C#CC1(O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C(\[H])=C(/[H])C1=C(N(N=C1C([H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]N1N=C([H])C(=C1[H])C1=C([H])N=C2N=C([H])C(=C([H])N12)C1=C([H])N([H])N=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=NC2=C(C([H])=C3C(N([H])[C@]4([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]34[H])=C2[H])C(=C1[H])C(F)(F)F
[H]N1C([H])=NN=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=C([H])C(F)=C3[H])N3C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N([H])C1=C2C([H])=C(N([H])C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])OC3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C([H])C2=C([H])C(=N1)C([H])([H])[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N1C(=NC(=C1C(=O)N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(SC(=C1[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N1C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])[C@]([H])(F)C2([H])[H])=C1[H])C1=NN(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])[H])=C(OC([H])([H])[C@@]2([H])OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC1=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])O[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C([H])C([H])=C(Br)C([H])=C2C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C(=O)OC([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[C@]1([H])N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=O)[C@](O1)(C1=C([H])SC(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)O\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])N([H])[C@]1([H])C(=O)N([H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)C(N([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])C1=NC2=C([H])C([H])=C(C([H])=C2N1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]C(=O)O[C@]1([H])C(=O)[C@@]2([H])[C@@](C([H])([H])[H])(C([H])([H])C([H])([H])[C@@]3([H])C(=O)O[C@]([H])(C4=C([H])OC([H])=C4[H])C([H])([H])[C@]23C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C#N)C([O-])=O
[H]C1=C([H])C(=C([H])C([H])=C1F)C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]12[H]
[H]C1=C([H])N(N=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1(F)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])[C@]([H])(C(=O)C1=C(C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
CN1C(OCC2=CC=C(Cl)C=C2)=CC2=C1C(=O)N(C)C(=O)N2C
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N1C([H])([H])C([H])([H])N2C([H])([H])[C@@]([H])(C([H])([H])N([H])C([H])([H])C3=C([H])C([H])=NC([H])=C3[H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]O[C@]([H])(C(\[H])=C(/[H])C(=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN=NN1C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]OC(=O)C([H])([H])C1=NN(N=C1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=C(C2=C([H])C([H])=C(S2)C([H])([H])[H])C1=O)C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
ClC1=C(Cl)C(=CC=C1)N1CCN(CCCNS(=O)(=O)C2=CC3=CC=CN=C3C=C2)CC1
[H]OC1=C(C([H])=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C(=C23)C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])[C@]3([H])C([H])([H])[C@]3(C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N(C1=C(C#N)C(=NC2=C([H])C([H])=C(F)C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C(C(=O)OC([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]OC1=NC2=C([H])C(Cl)=C(C([H])=C2C(OC([H])([H])C([H])([H])[C@@]2([H])N([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])C#N)C([H])([H])[H])[N+]([O-])=O
[H]N(C(N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])=C(C#N)C#N)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(\C(S1)=N\C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
ON(=O)C1=CN=C(SC2=NN=C(NCC3CCCO3)S2)S1
[H]N(C(=O)N([H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])OC(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])C([H])([H])N(C1=C([H])C(=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]1([H])C([H])([H])C2=C([H])C([H])=C([H])C(C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3OC([H])([H])[H])=C2C([H])([H])C1([H])[H]
O=S(=O)(CCCC1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1)C1=CC=CC=C1
[H]N([H])C(C(=O)N1C([H])([H])C2=NC(=C(N([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])N2C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])N(C1=C2C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C1=C([H])SC([H])=N1
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)N1C([H])([H])C([H])([H])C2(OC3=C([H])C([H])=C(C([H])=C3C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
CC(=O)N[C@@H](CC1=CC(F)=CC(F)=C1)[C@H](O)CNC1(CC1)C1=CN=CC(CC(C)(C)C)=C1
[H]N(C1=C2C(N([H])N=C2S(=O)(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)N([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C(F)=C([H])C(=C1[H])C(=O)N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1\C(=N/C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])N(C2=C(OC([H])([H])[H])C([H])=C(Cl)C([H])=C12)C([H])([H])[H])C1=NN=NN1[H]
[H]N(C1=C2C(=NN1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N([C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
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[H]N([H])S(=O)(=O)C1=C([H])N=C([H])C([H])=C1OC([H])([H])[H]
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[H]C1=C(C(=NN1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C(C([H])=C(Br)C(=C1[H])N1N=NC2=C1N=C(N=C2N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C(SC([H])([H])[H])=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=[N+]([O-])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])N2C(=O)N(C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])C([H])([H])C2=O)C([H])=C1[H]
BrC1=CC2=C(NC(=O)C2=C(C2=NC3=CC=CC=C3N2)C2=CC=CC=C2)C=C1
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])N(C(=O)[C@@]1(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=NN(N=N1)C([H])([H])C([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(Cl)=C([H])C([H])=C2N2C([H])=C([H])C([H])=C12)C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C(Cl)N(C2=NC(=C(N12)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])[H])C(F)(F)F)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN=C(SC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC(=NC(=N1)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C2=C([H])N=C([H])O2)C(OC([H])([H])[H])=C1[H]
[H]N([H])C(=O)C(=O)C1=C(N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])N(N=C1[H])C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N([H])C1=C([H])N=C([H])C(=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])=C2C(=N1)C1=C([H])C([H])=C([H])C([H])=C1C2([H])[H]
[H]N([H])C1=C(N([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)C2=C(Br)C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)N([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])O[N+]([O-])=O)C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C1=NN(C(OC([H])([H])C([H])([H])C2=NC3=C(N([H])C([H])([H])C([H])([H])N3[H])C([H])=C2[H])=C1[H])C([H])([H])[H]
[H]C1=NC(OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C(=C2[H])C(=O)C([H])([H])[H])C2=NC([H])=C([H])C([H])=C2C1=O)C1=NC([H])=C([H])C(Cl)=C1Cl
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@](=O)(O[H])O[P@](=O)(O[H])OC([H])([H])[C@@]2([H])O[C@@]([H])(C3=NC(=C([H])S3)C(=O)N([H])[H])[C@]([H])(O[H])[C@]2([H])O[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(I)N=C2N([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C(F)=C(F)C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(S1)C([H])=C([H])C(N([H])[H])=C2[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(S2)C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(I)=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)O[C@]([H])(C([H])([H])N1C([H])=NC2=C1C([H])=C(Cl)C(Cl)=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])C([H])=C(S1)C([H])([H])C([H])([H])C(N([H])C(=O)C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C(F)=C(F)C([H])=C1C1=C([H])C(Cl)=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])N(C(=O)C2([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C2C([H])=C([H])C(=NC2=C1O[H])C(=O)N([H])C([H])([H])C1=C(O[H])C([H])=C(O[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])C(=O)C([H])=C([H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC(Cl)=C1C1=C([H])C([H])=C([H])C(N([H])[H])=C1[H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC3=C(N=C([H])N3C([H])(C([H])([H])[H])C([H])([H])[H])C(=N2)N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NN(C(=O)C(OC2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=NN1C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]OC1=C([H])C(Br)=C2OC(=C([H])C2=C1[H])C1=C([H])C(F)=C(O[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2N=C(N(C2=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=C(C3=C([H])C([H])=C([H])O3)C3=C(N=C([H])N=C23)N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C([H])([H])C(F)(F)F)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C(N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(S[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2C(=C1[H])[C@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C3SC([H])([H])C([H])([H])C3=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=NN(C([H])=C1C1=NC([H])([H])C2=C1C(OC([H])([H])[H])=NC([H])=C2[H])C1([H])C([H])([H])OC1([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(C(=O)N([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=N2)C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C(C(=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])OC2=C([H])C([H])=C([H])C3=C2N=C(N3C([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C(C([H])=C2O[C@@]([H])(C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C(C2=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(O[C@]([H])(N2C(=O)C([H])([H])[H])C2=C([H])C([H])=C(Br)C([H])=C2[H])N=C(SC([H])([H])[H])N=N1
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[H]O[C@]([H])(C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(C#N)(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[N+]2(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])N=C(N=C1C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C(F)C([H])=C(F)C([H])=C1[H])C1=NC(SC([H])([H])C([H])([H])C([H])([H])[H])=NS1
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=NN2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(\C([H])=C(/[H])C(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C(F)=C(F)C([H])=C1[H]
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[H]O[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(=C2[H])C([H])([H])C([H])([H])C([H])([H])O[H])C(=N1)N([H])[C@]1([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(C(=O)N([H])[C@@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2O[C@]2(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)(C([H])([H])[H])C([H])([H])[H]
[H]ON(C(=O)[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3(C(=C([H])C(=O)[C@]4([H])[C@@]5(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(OC6=NOC(=O)N6[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]5([H])C([H])([H])C([H])([H])[C@@]34C([H])([H])[H])[C@]2([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C2C3=C(C([H])=C([H])C([H])=C13)[C@@]1([H])C([H])([H])[C@@]([H])(C(=O)O[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C2([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H])C(=O)N([H])[H]
[H]N(C1=C([H])C([H])=C2N=C(N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C(F)(F)F
[H]N(\C(=N/C#N)N([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(F)C(F)=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)O2
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=S)SS1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@](C1=C([H])N=C([H])N1C([H])([H])[H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C([H])=C2C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C(C2=C([H])C(=C(N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])[N+]([O-])=O)C(=N1)C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1C(=NN=C1C([H])([H])[H])C1=C([H])C2=C(OC([H])=C2C2=C([H])C([H])=C(C([H])=C2[H])[S@](=O)C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])N(N=N2)C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])OC2=C([H])C(=C([H])C([H])=C2C(=O)C1([H])[H])C([H])([H])[H]
[H]C1=C(C(N2C3=NC(=C(N3C([H])([H])C([H])([H])C2([H])[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C(F)(F)F)=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])C([H])=C([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])=C([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N1C(=O)C2=C(N(C(=C2[H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C3=C(C([H])=C2[C@@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C(=C([H])C(=O)O3)C(F)(F)F
[H]N(C(=O)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(F)(F)F
[H]OC(C(=O)N([H])C1=C([H])C(=C(C([H])=C1[H])[N+]([O-])=O)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(F)=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])S2)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]O[C@@]([H])([C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])=C([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)C(=O)N([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C1([H])C([H])([H])C1([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=C1[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NN(C2=NC([H])=C(C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@](C#CC1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])OC([H])=N1
[H]N(C([H])([H])C([H])([H])OC([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
OC(CNC1CCN(CC1)C1=NC=NC2=C1C(=CS2)C1=CC=C(F)C=C1)COC1=CC=C(O)C=C1
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[H]OC1=NSC(N([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])=C1C#N
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])N1C(=O)O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
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[H]OC(=O)C1=C([H])N=C(OC([H])([H])C([H])([H])OC2=NC([H])=NC(N([H])S(=O)(=O)C3=C([H])C([H])=C(C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])N=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]O\C(C1=C(N(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])=C1\C(=O)C(=O)N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C1=C([H])C([H])=C(O1)C([H])([H])[H]
[H]OC1(C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N(C(=C(C2=C1[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1N=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)C4=C([H])C([H])=C([H])C([H])=C4[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N([H])C(=O)C([H])([H])C([H])([H])SSC([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])C(=O)OC21C2=C([H])C([H])=C(O[H])C([H])=C2OC2=C1C([H])=C([H])C(O[H])=C2[H]
[H]N(C(=O)C([H])([H])N1N=NC(=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N([H])C([H])([H])[H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])C([H])([H])SC([H])([H])[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C2C([H])=C(SC2=C(C([H])=N1)C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC3=C(O2)C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C(F)(F)F)N=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1S(=O)(=O)C([H])([H])[H]
CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1)B(O)O
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[H]OC1=C([H])C([H])=C(C([H])=C1I)C1(OC(=O)C2=C1C1=C(C([H])=C([H])C([H])=C1[H])C([H])=C2[H])C1=C([H])C(I)=C(O[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C(Cl)C([H])=C1Cl)S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N(C([H])=N1)C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])[H])C1=NN(C([H])=C1[H])C([H])([H])[H]
[H]N(N1C(=O)C([H])=C(C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N2C(S1)=NC(Cl)=C2S(=O)(=O)C1=C([H])N(C2=NC([H])=C([H])C([H])=C12)[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C(Br)C([H])=C([H])C2=C1[H]
[H]N1C(=S)N(C(=O)C2=C([H])C([H])=C([H])C(Cl)=C12)C1=C(F)C([H])=C([H])C([H])=C1F
[H]N(C(=O)C1=C(C([H])=C([H])C(F)=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1Br)C([H])([H])[C@@]1([H])SC(=S)N(C1=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C(C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C2=C(N1[H])C([H])=C(Cl)C(=C2[H])C(N([H])[H])=[N+]([H])[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C2=C3N(C(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C3=C1[H]
[H]N(C1=NC([H])=NN2C([H])=C([H])C(=C12)C([H])([H])OC([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])N([H])C1([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC([H])=C2C(=C1[H])N(N=C2C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C(S2)C(=O)N([H])C([H])([H])C2=C(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C([H])C(Cl)=C([H])C([H])=C3C2=O)C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C([H])C(=C([H])C([H])=C2C(=N1)N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)S(=O)(=O)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]1([H])N2C(=NC3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=O)O2)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C([H])C(Cl)=C3[H])S2(=O)=O)C([H])([H])C1([H])[H]
CC(C)Nc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(F)c1
[H]OC([H])([H])C([H])([H])ON([H])C(=O)C1=C(N([H])C2=C([H])C([H])=C(C#C[H])C([H])=C2F)N(C2=C1C([H])([H])C([H])([H])C2=O)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])C2=C([H])C3=C(C([H])=C2[H])N(C(=O)C([H])=C3[H])C([H])([H])[H])=C1[H])C1(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(=NC([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C1[H])S2(=O)=O
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]C1=C(F)C([H])=C(C(=C1[H])[C@@]1([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=NOC(=N1)C(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[P@@](=O)(OC1=C(Cl)C([H])=C([H])C([H])=C1[H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]C1=C(SC2=C1C(=NC([H])([H])C1=NN=C(N21)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C#CC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N([H])C([H])([H])C1=C(N=C(C(=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])N([H])C([H])([H])C4([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C(=O)N([H])C1=C(F)C([H])=C(F)C([H])=C1[H])C1=C([H])C(C2=C(Cl)C([H])=NN2C([H])([H])[H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(N=C1[H])C(=C1C([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1OC([H])([H])C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])([H])[C@@]3([H])C([H])([H])[C@]2([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(F)=C([H])C(=C1[H])C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]OC([H])([H])C1=C([H])C([H])=C(C(=C1[H])N(C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Cl)C(Cl)=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(OC3=C(C([H])=C([H])C([H])=C3[H])[C@]2([H])C(C(=O)N([H])C2=NC([H])=C([H])S2)(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]O\C(=C(\C#N)C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(N([H])S(=O)(=O)C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])N(C2=C([H])C3=C(C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C(\[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C(Br)=C1[H])C1=NC([H])=NC2=C1C(Cl)=C1N=C([H])N(C1=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(N=C1\N=N\C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C(\[H])=C1\C([H])([H])[N@+]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@]34C5=C([H])C([H])=C([H])C([H])=C5N5\C([H])=C6/[C@]7([H])N(\C([H])=C(/[C@@]35[H])[C@@]1([H])C([H])([H])[C@]24[H])C1=C(C([H])=C([H])C([H])=C1[H])[C@@]71C([H])([H])C([H])([H])[N@@+]2(C([H])([H])[H])C([H])([H])\C(=C(/[H])C([H])([H])O[H])[C@]6([H])C([H])([H])[C@@]12[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C12
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2C2=NN=C([H])N2[H])C2=C([H])N=C([H])C([H])=C12)C1=C([H])C(F)=C([H])C([H])=C1C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N1C([H])=NC2=C([H])C(C#C[C@@]3(N([H])C(=O)N([H])C3=O)C([H])([H])N3C(=O)C4=C(C([H])=C([H])C(OC([H])([H])[H])=C4[H])C3([H])[H])=C([H])C([H])=C12
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C(C(=O)N(C([H])([H])C2=C(C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])[H])C2([H])C([H])([H])C2([H])[H])=C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])OC2=C(F)C([H])=C([H])C(F)=C2Cl)C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])N=C2C(C([H])=C([H])C([H])=C2C(F)(F)F)=C1C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])C([H])=C2C([H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C(F)C([H])=C([H])C(=C2[H])C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3S2)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C2C(=C([H])N(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1=O
[H]OC(=O)C1=C(C(=O)N([H])C2=C(F)C([H])=C(C([H])=C2F)C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C([H])([H])N(C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(N=C1[H])N([H])[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=C(S1)C1=NC(=C([H])N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F)C([H])([H])[H]
[H]N1C2=C(C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C2[H])C(=O)N(C([H])([H])[H])[C@]11C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C(=N2)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])[H])C(=O)C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)C4=C([H])C([H])=C([H])C([H])=C4[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)N([H])[H]
[H][C@@]1(CCCCN1CC1=CC=C(C=C1)[N+]([O-])=O)[C@H](C(=O)OC)C1=CC=CC=C1
[H]N(C(=O)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])(F)F)C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(N=C1[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@]2(OC(=O)C2=C([H])C([H])=C([H])O2)C(=O)C([H])([H])SC2=NC([H])=C([H])C(=N2)C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C(=O)C([H])=C([H])[C@]3(C([H])([H])[H])[C@@]12[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]1([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
COC1=CC(\C=C2/CCC\C(=C/C3=CC(=C(O)C(=C3)C(C)(C)C)C(C)(C)C)C2=O)=CC(OC)=C1
[H]OC1=C([H])C(I)=C(C([H])=C1OC([H])([H])[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)[C@]2([H])ON(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)[C@]2([H])C1=O
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])=C1[H])C([H])([H])N1C2=C([H])C(OC3([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])C([H])=C2N=C1C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C2([H])[H])[C@](O[H])(C2=C([H])C([H])=C([H])C(Cl)=C2C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[C@@]1([H])N([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=NS2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=N1
[H]C1=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C2=C(C([H])=C([H])C(Cl)=C2[H])N1S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)S1)[C@@]1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C([H])C1=O
[H]N(C(=O)C([H])([H])Cl)C1=C([H])C(=C(S1)C1=NN=C2SC(=NN12)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])C1=C(OC([H])([H])[H])C(=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C(C([H])=C([H])C(Br)=C2[H])N1S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@]1([H])[C@]([H])(O[H])[C@]([H])(O[C@@]1([H])C1=NC2=C(S1)C([H])=C(Cl)C([H])=C2F)C([H])([H])O[P@](=O)(O[H])O[P@](=O)(O[H])OP(=O)(O[H])O[H]
[H]N1C(=O)N(C([H])([H])C1(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])[N@@+](C([H])([H])[H])(C([H])([H])C(=O)C2=C([H])C(F)=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C1=C([H])C(=NC(=C1[H])C([H])([H])C([H])([H])[H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])N([H])C2=C(C([H])=C([H])C([H])=C2[H])S1(=O)=O
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1(N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C(=O)C([H])([H])C4(C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3=O)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])O2
[H]N1C(=NC2=C1C([H])=C(F)C(F)=C2[H])N(C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C([H])C(C#N)=C3[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=NC(=C([H])S2)C([H])([H])[H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)C([H])([H])O[C@@]1([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2(OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])O2)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C(=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])C1=C(F)C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])[C@]1([H])[C@]2([H])C3=C(C(=NN3[H])C3=NN=NN3[H])C([H])([H])[C@]12[H]
[H]N(C(=O)C1=C([H])C2=C(OC([H])([H])C1([H])[H])C([H])=C([H])C(Br)=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C(=O)C2=C(O[H])C([H])=C(C([H])=C2O[H])C(=O)O[C@]2([H])C([H])([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])([H])[C@@]2([H])N([H])C(=O)C2=C([H])C([H])=C(O[H])C([H])=C2[H])C(O[H])=C([H])C([H])=C1[H]
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[H]N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N1C(=S)N(C(=O)C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C#N)C([H])=C1[H])C(F)(F)F
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[H]N(C(=O)[C@]([H])(N1C([H])([H])C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])[C@]1([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)[C@@]([H])(OC([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C([H])=NN(C2=C1C([H])([H])[H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])[H]
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COC1=CC=C(C=C1)[C@@H]1CC(=NN1)C1=C2C=CC=CC2=CC2=CC=CC=C12
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[H]OC(=O)C([H])([H])C([H])([H])C1=C(N([H])C([H])=C1C([H])([H])[H])C(\[H])=C1/C(=O)N([H])C2=C([H])C(=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])[H])=C1[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]1([H])C2=C(C([H])=C([H])C(Cl)=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C(F)C([H])=C(F)C([H])=C1F)C([H])([H])OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])C2=C([H])C([H])=NC([H])=N2)C([H])=C1[H])C1=NC(=C([H])S1)C1=C(F)C(Br)=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N(N=C(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C1([H])[H])C(=O)C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])OC(=O)N([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@@]([H])(C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NN(C(=C1[H])C1=C([H])C(=NC2=C(OC([H])([H])C3=C(Cl)C([H])=NC([H])=C3Cl)C([H])=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C2=C([H])C3=C(C([H])=C2C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])N(C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C3([H])[H]
CN1C(C)=CC2=C1C(=NN=C2NCCCN1CCN(CC1)C(=O)C1=NC=CC=C1)C1=CC=CC(=C1)N(O)=O
[H]C1=C([H])C(F)=C([H])C(=C1[H])C1=C([H])C([H])([H])C([H])([H])N(C2=NC(=NC(=C2[H])C([H])([H])[H])N(C2=C([H])C([H])=C(C([H])=C2SC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])[H]
COC1=C(F)C2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=CC=C(CN4CCC5=C(C4)C=C(F)C=C5)N=C3)C2=O)C=C1
[H]C1=NC([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C(Cl)=C2C(=O)N(C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])C3([H])[H])=N1)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1N=C([H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N(N=C1C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C3=NC([H])=C(S3)C3=C([H])C(=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C3[H])C([H])([H])[H])C(=N2)C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C2C(OC([H])=C2C2=C(C(=O)N([H])C2=O)C2=C([H])N(C3=C([H])C([H])=C(F)C([H])=C23)C([H])([H])[H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C3=C1C([H])=C([H])C([H])=C3[H])C(=O)N([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])N=C([H])N2[H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C(=N1)C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)[C@@]([H])(N([H])C(=O)C1=C([H])C(N2C(=O)C([H])([H])C([H])([H])C2([H])[H])=C2N(C([H])=C(C2=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(=NN(C1=O)[C@]([H])(C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=C(N=C1Cl)C(F)(F)F
[H]N([H])C1=C(C([H])=C(C([H])=N1)C1=C([H])N(N=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=NC2=C(O1)C(F)=C([H])C(Cl)=C2[H]
CC1(C)CN([C@H]2C3CC4CC2C[C@@](O)(C4)C3)C(=O)C2=C(C1)N(N=C2)C1=CC=CC=C1
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[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)N2N=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C4C(=N3)C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NC(=NC([H])=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(S1)[C@]1([H])C(C#N)=C2SC([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])N2C(=O)C1([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C(Br)=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C2C(=C([H])C([H])=C1[H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=C(N(N=C2[H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N2C(=O)N(C(=O)[C@@]2([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Cl)C(Cl)=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C(N(C2=C([H])C(=C([H])C([H])=C12)C1=NN=C([H])O1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)C(=NC([H])=C1C([H])([H])[H])N([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1(C2=C([H])C([H])=C([H])S2)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(Cl)=C(C([H])=C1[H])C1=NN=C(N1C([H])([H])[H])C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(N([H])C1=C([H])C([H])=C(F)C(=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])[C@@]([H])(C([H])([H])OC([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])OC1=C([H])C([H])=C([H])C2=C([H])C([H])=C(N=C12)C1=NN=C2C([H])=C([H])C([H])=C([H])N12
[H]N(C([H])([H])C(=O)N1N=C([H])C([H])([H])[C@]1([H])C#N)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])N3C2=NC([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C#CC1=C([H])N=C(N(C1=O)C([H])([H])C1=C(C#N)C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])[C@@]([H])(N(C([H])([H])[C@@]1([H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C(Cl)SC(Cl)=C1C(=O)C([H])([H])Cl
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=NN1[H])C([H])([H])C#N
[H]OC(=O)C1=C([H])C([H])=C([H])C(=N1)C1=C([H])N=C(O1)C(=O)[C@@]1([H])C([H])([H])C2=C(C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC3=C([H])C(F)=C(F)C([H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
CNc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)NCc1ccccc1
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(SC2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C(Cl)=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])[H]
[H]C1=NC(=C(O1)C1=C([H])C([H])=C2N(C(=O)N(C2=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])OC1=C2C([H])=C(N([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C3=C(SC([H])=C3[H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])[H])C([H])([H])C1=NC2=C([H])C(=C(Cl)C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=C2C(=N1)N(C(=O)C(C1=C([H])C([H])=C([H])C([H])=C1Cl)=C2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C([H])N1[H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])N2C(=O)C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)[C@]([H])(C1=NN=NN1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=NN(C1=O)C([H])([H])[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC(=C([H])S1)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)OC([H])([H])[H])\C(C2=C([H])C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C([H])C([H])=C12)=[N+](\[O-])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C([H])=C([H])C2=NC([H])=NC2=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])N(C2=C1C1=C(OC([H])([H])C([H])([H])C1([H])[H])C([H])=C2[H])C([H])([H])[H]
[H]OC1=C2C(=O)OC([H])([H])C2=C(C(OC([H])([H])[H])=C1C([H])([H])C([H])([H])O[P@@](=O)(O[H])C([H])([H])C([H])([H])[P@@](=O)(O[H])OC([H])([H])[C@]1([H])O[C@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])[H])[C@@]([H])(O[H])[C@@]1([H])O[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C2([H])[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C#N
[H]OC1=C([H])C([H])=C(\C([H])=N\OC(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]OC1=NSC(N([H])C2=C([H])N=C([H])C([H])=C2[H])=C1C#N
[H]OC1(C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)N1N=NN=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)N([H])C1=C(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2N=C1[H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]N1C([H])=C(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C(=NC3=C2C([H])=C([H])N=C3[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C12
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(C1=C([H])N2C([H])=C(Cl)C([H])=C([H])C2=N1)(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C(O1)C1=C([H])N2C(=NN=C2C2(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N(C1=C([H])C([H])=C2N=C(N(C2=C1[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C(=C([H])C2=C1[H])C(=N[H])N([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]2([H])N(C1=O)C([H])([H])C([H])([H])C2([H])[H])C(=O)O[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)N([H])C1=C(C([H])=C(C(Cl)=C1[H])S(=O)(=O)N([H])[H])S(=O)(=O)N([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])C1=C(C([H])=C(C(Cl)=C1[H])S(=O)(=O)N([H])[H])S(=O)(=O)N([H])[H]
[H]N1C(=NC2=C1C([H])=C([H])C(Br)=C2[H])C([H])([H])OC1=NOC(=C1[H])C1=NC2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])C(C(=O)N([H])[H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
ClC1=CC2=C(C=C1)N=CN(C(CC1CCCCC1)C(=O)NC1=NC=CS1)C2=O
[H]ON([H])C(=O)[C@]([H])(C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C2=C([H])SC(=N2)C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])C2=NOC(=N2)C([H])([H])C2(C([H])([H])C2([H])[H])[C@]2([H])N([C@@]([H])(C([H])([H])C([H])([H])C2([H])[H])C2([H])C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=[N+]([O-])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C2=C(O1)C(=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])[C@]([H])(N([H])C(=O)C4=C([H])C([H])=NC([H])=C4Br)C([H])([H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]C1=C([H])C(=C(C([H])=N1)C1=C([H])C([H])=C(F)C([H])=C1[H])[C@@]1([H])SC([H])([H])C(=O)N1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])[C@@]([H])(N(C([H])([H])C(=O)N([H])C2([H])C3=C([H])C([H])=C([H])C([H])=C3C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C1=C([H])C([H])=C([H])C2=C1C(=O)N([H])C2([H])[H]
[H]N([H])C1=NC(=C([H])N2N=C(N=C12)C1=C([H])C([H])=C([H])O1)C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C1=NC(=C(N1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N1C(=O)[C@@]([H])(N([H])C(=O)C2=C([H])C3=C(SC(Cl)=C3[H])N2[H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C(F)C([H])=C2C(N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2=O)=C1[H])C(C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
CC(C)=CC(=O)CCC(=O)N1CCN(CC2=CC3=C(S2)C(=NC(=N3)C2=CC=CC3=C2C=NN3)N2CCOCC2)CC1
[H]OC(=O)C([H])([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(S2)C2=C(C([H])=C([H])C(O[H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=NC2=C(C([H])=C1C#N)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(=NS1)C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])N2C1=NC([H])=C2C1=C([H])N(N=C1[H])C([H])([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3N([H])\C(=N/C(=O)C4=C([H])C([H])=C(C#N)C(F)=C4[H])N(C3=C2[H])[C@@]2([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)S(=O)(=O)N1C(=O)[C@@]([H])(C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2OC([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C(=O)C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)O[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)N3C([H])=C([H])C([H])=C([H])C3=C(C2=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C([H])N([H])C4=C3C(=C([H])C(=C4[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]2([H])C1([H])[H])C1=NC([H])=C([H])S1
[H]N(C(=O)C([H])([H])[H])[C@]1([H])C2=C([H])C(=O)C(SC([H])([H])[H])=C([H])C([H])=C2C2=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]\C(=C(\[H])C1=C([H])C2=C(C([H])=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C2([H])[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H]
[H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])S[S@@](=O)C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
CC1=CC(=CC=C1)C(C)(C)CN(CC(=O)NCC(=O)N[C@@H](CCCNC(N)=N)B(O)O)C(=O)CCC1=CC=CC=C1
[H]N(\N=C(/[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C(=O)C1=C([H])C2=C(N1[H])C([H])=C(OC([H])([H])[H])C([H])=C2OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C(=O)N([H])C2=C([H])C(Cl)=C(C([H])=C2[H])C(=O)N2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])[C@]3([H])C2([H])[H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1C(=O)O[H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C(C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C(S1)C(=NC([H])=N2)N([H])C1=C([H])C(Cl)=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=C(C([H])([H])N2[C@@]3([H])C([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C3([H])[H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1O[H])N1C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N1C2=NC3=C(N2C([H])=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)N(C(=O)N3C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C2C([H])=NN(C2=NC([H])=N1)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(=C([H])S1)C1=NC2=C([H])C([H])=C(C([H])=C2S1)[N+]([O-])=O
[H]N([H])S(=O)(=O)[C@]1([H])O[C@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]1([H])OC(=O)C([H])([H])[H]
[H]C1=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C3=NSC4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])[H])C([H])([H])C2([H])[H])C2=C(S1)C([H])=C(F)C([H])=C2[H]
[H]N(C(=O)[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@@]1([H])C([H])([H])[C@]([H])(C2([H])[H])C3([H])[H])C1=C(C(=O)N2C([H])([H])C(F)(F)C2([H])[H])C2=C(S1)C([H])([H])OC([H])([H])C2([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])ON1C(=O)N(C(=O)C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C#N)C([H])=C1[H])C(F)(F)F)C(=O)N([H])[H]
[H]N=C(N([H])[H])N([H])OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC1=C([H])C(N([H])C(=O)C2=C(OC([H])([H])C3=C([H])C([H])=C([H])C(C#N)=C3[H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C3=NOC(=N3)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C(OC([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])\C2=C(\[H])C([H])([H])N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=C2N=C(SC3=C(I)C([H])=C4OC([H])([H])OC4=C3[H])N(C2=NC([H])=N1)C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1(O[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]2(C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C1([H])[H]
[H]O[C@@](C1=C([H])C([H])=C(C([H])=C1[H])N(C1([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)(C([H])([H])[H])C(F)(F)F
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2N=C(N([H])C2=NC([H])=C1Br)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@]1(C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(Br)=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]N(C1=NC2=C([H])C([H])=C(C([H])=C2N2C([H])=NC([H])=C12)N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
COC1=C(C=CC(NC2=NC=CC(=C2)C2=CC(=CC=C2)C#N)=C1)N1CCN(C)CC1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C1=C(C([H])=C([H])C(Cl)=N1)C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])N(C3=NC([H])=C(N=C3Cl)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])C([H])([H])N(C(=O)OC([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2F)=C1[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])S1)[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(C2=C([H])C([H])=C([H])O2)=C2N=C([H])N(C2=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2N(C(=C(C(=O)N3C([H])([H])C([H])([H])N([H])C([H])([H])C3([H])[H])C2=N1)C([H])([H])C1=C(C(F)=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C(N([H])C(=O)C([H])([H])[N+]2=C(C([H])=C(C([H])=C2C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C(C1=C([H])C([H])=C2N(C(=O)SC2=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(N([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(O[C@]([H])(C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1Cl
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[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C([H])([H])[C@@]([H])(O[H])C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
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[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[C@]3([H])C([H])([H])[C@]3(C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])[H]
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[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])=C1[H]
[H]N([H])N([H])C(=O)C([H])([H])SC1=NN=C(N1N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C(F)(F)F)C([H])([H])N(N1C([H])=NN=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]O[C@]1([H])[C@]([H])(O[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@@]1(O[H])C([H])([H])[H])C([H])([H])OC(=S)N([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NC([H])=C(S1)C1=C([H])C2=C(C([H])=NN([H])C2=O)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
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[H]N1C(=O)S[C@@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C(=O)OC1=C([H])C([H])=C([H])C2=C1C1=C3C(=C([H])C(F)=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]3([H])C2([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C11C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])ON1C(=O)C([H])([H])S[C@@]1([H])C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)SC1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N1N(C(=O)N([H])C2=C([H])C([H])=C([H])C(C#N)=C2[H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N([H])C2=NC([H])=C([H])C(=C2[H])C2=NN3C(N=C([H])C([H])=C3C3=C([H])C(N([H])C(=O)C4=C([H])C(=C([H])C([H])=C4[H])C(F)(F)F)=C([H])C([H])=C3[H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C(=O)N([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C(=O)N([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(S1)N=C(N([H])C([H])([H])C([H])([H])[H])C1=C2N(C([H])=N1)C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1Cl)C(=O)N([H])\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
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[H]N(C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(Cl)=N2)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=NC2=C(S1)C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC([H])([H])[C@@]([H])(O[H])[C@]([H])(N([H])C([H])([H])C1=C([H])N([H])C2=C1N=C(N([H])[H])N([H])C2=O)C([H])([H])O[H]
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[H]N([H])C(=O)C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1[C@@]2([H])C(C(=O)N(C([H])([H])C3=C(Cl)C(Cl)=C([H])C([H])=C3[H])C3([H])C([H])([H])C3([H])[H])=C(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])OC3=C(Cl)C([H])=C(C([H])=C3Cl)C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])N(C(=O)C([H])([H])[H])C2([H])[H]
[H]N([H])C(=O)C1=C(OC([H])([H])[H])C([H])=C(S1)N1C([H])=NC2=C1C([H])=C([H])C([H])=C2[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
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[H]N1C([H])=C(C2=C([H])C(=C([H])C([H])=C12)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
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[H]N1C(=NC2=C1C([H])([H])N(C(=O)C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N([H])C1=O
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[H]N1N=C([H])C2=C(C([H])=C([H])C(Cl)=C12)C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=NC([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]O[C@]([H])(C1=C([H])C2=C(N([H])C(=O)C([H])([H])C2([H])[H])C([H])=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])C(O[H])(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C2=NN=C3SC([H])([H])C(=NN23)C2=C([H])C(OC3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C(Cl)=C1[H]
[H]C1=NN=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C2=C(S1)C(=NC(=N2)N([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])[H]
[H]C([H])=C1C(=O)O[C@]2([H])[C@]3([H])C(C(=O)C([H])=C3C([H])([H])[H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]12[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C2N([H])C(=O)C(C3=NC([H])=C([H])S3)=C(C2=C1[H])C([H])([H])C([H])([H])C(F)(F)F)C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(\C([H])=C(/[H])N2C3=NC([H])=NC(N([H])C4([H])C([H])([H])C4([H])[H])=C3N([H])C2([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)N1C([H])=NC(=C1[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
CN1C=C(C2=NC3=C(O2)C=C(CC(=O)N2C[C@@H](F)C[C@H]2CO[C@H]2CC[C@@H](CC2)C(O)=O)C=C3)C2=C1C=CC(Cl)=C2
[H]C1=C(SC([H])([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])N(N=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(\N=C(\N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])C1=NC2=C(N1[H])C(=C([H])C([H])=C2[H])C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1(C#N)C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=NC(=N1)C([H])([H])N([H])C(\[H])=C1/C(=O)N([H])C(=O)C2=C([H])C([H])=C(I)C([H])=C12
[H]C1=C([H])C(=NC(=C1F)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(C(=O)C3=C([H])C([H])=C(C([H])=C23)C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC(=O)C1=C(N([H])[H])C([H])=C(O1)C1=C(F)C([H])=C([H])C(F)=C1[H])N([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C2C(=NN([H])C2=N1)N([H])C(=O)C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(C2=NN(C3=C2N=C(C([H])=C3N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C3=C(C([H])=C([H])C4=C3C(O[H])=NC(=N4)C([H])([H])[H])C([H])=C2[H])C([H])=C1F)C(=O)O[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1(C([H])([H])N([H])C(=O)N([H])C2=C(C([H])=C([H])C([H])=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C(N(C([H])([H])[H])C([H])([H])C3=C([H])C([H])=NN=C3[H])C3=C([H])C([H])=C([H])C1=C23
[H]C1=C([H])C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C2C([H])=C(C(=NC2=C1OC([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(C#N)C([H])=C1OC([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C3=C([H])C([H])=C([H])C([H])=C3N=C2C([H])([H])OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])N(C(=O)C([H])([H])N2C(=O)[C@@]([H])(N([H])C(=N\C#N)\N([H])C3=C([H])C4=C(OC(=C4[H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(SC([H])([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])N(N=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(N([H])C(=O)C1=C([H])C(Br)=C([H])N=C1[H])C(\[H])=C1/C([H])=C(C([H])=C(OC([H])([H])[H])C1=O)[N+]([O-])=O
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])OC(=O)C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[C@@]1([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C1=NC(=C([H])O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C2N([H])N=C(C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C(OC([H])([H])[H])=C2C(=C1[H])[C@]([H])(C([H])([H])[H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N1C(OC([H])([H])C#CC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=NC2=C(C1=O)C(=C([H])C(=O)O2)C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])[C@@](O[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]23[H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)C2=C([H])C3=C([H])C(=C([H])C([H])=C3O2)C(=N[H])N([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(C2=C(C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=N3)=C2[H])C2=NN(N=N2)C([H])(F)F)C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C(O[H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)ON=C1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C1=C([H])C2=C(N([H])C([H])=C2C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C(C2=C([H])C(Cl)=C([H])C([H])=C2S1)C([H])([H])[H]
[H]C1=C([H])C([H])=C(O1)C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])[C@@]1([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C(C2=C([H])C([H])=C([H])N=C2N1[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])S(=O)(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C(C2=C([H])C([H])=C([H])C([H])=C2S1)[C@]([H])(C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(N([H])C2=NC(=C([H])C([H])=N2)C2=C3C([H])=C([H])C([H])=NN3N=C2[H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])=NC([H])=C2[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C([H])C([H])=C2C2=NN=C(N2C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)N1C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SN=N1)C([H])([H])C1=C([H])C(F)=C(C([H])=C1[H])C(F)(F)S(=O)(=O)N([H])[H]
[H]N1C([H])=C([H])C2=C(C([H])=C(O2)C2=C([H])C([H])=NC([H])=C2[H])C1=O
[H]O[C@]([H])(C(=O)N([H])C1=C(OC([H])([H])[H])C([H])=C(N([H])C(=O)C(\[H])=C(/[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])=C1[H])[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O
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[H]N(C1=NC([H])=C([H])C(=N1)C1=C(N([H])N2C([H])=C([H])C([H])=C([H])[C@]12[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C([H])=C(\C([H])=C2/OC(=S)N(C2=O)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])=C1Br
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])O1)C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=NOC(=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C([H])C(\C([H])=C(/[H])C3=NC4=C(C([H])=C([H])C(Cl)=C4[H])C([H])=C3[H])=C2C([H])=C1[H]
[H]O[C@@](C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C(F)(F)C1([H])[H]
[H]SC1=NC2=C(OC([H])([H])C([H])([H])N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2N1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[C@]2([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NN1C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])N=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])(C1=C2C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=N\C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])\N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]OC(=O)C([H])([H])N(C1=C([H])C([H])=C([H])C([H])=C1O[H])C([H])([H])C([H])([H])N(C1=C(O[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N([H])C1=C(Cl)C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]\C(=C(\[H])[C@]1([H])[C@@]2([H])[C@@]([H])(C([H])=C3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]13[H])C(=O)OC2(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=N1
[H]OC(=O)C(OC1=C([H])C([H])=C(SC([H])([H])C2=NC(=NS2)C2=C([H])C([H])=C(C(Cl)=C2[H])C([H])([H])[H])C([H])=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(F)=C1[H])S(=O)(=O)C1(F)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=NC(=NC(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C12)C([H])([H])[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])N2C(=C1C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)N1C([H])=NC([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C1=NN2C(=N1)C([H])=C([H])C([H])=C2C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C(C([H])=C(OC([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])=C1[H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N([H])[C@]1([H])C2=C([H])C(=O)C(OC([H])([H])[H])=C([H])C([H])=C2C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=NC([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(O1)N([H])C([H])([H])C([H])([H])C([H])([H])N1[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C1([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C1=C(C([H])=C([H])C([H])=C1[H])N2[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
CN1C(=O)\C(=C2/NC3=CC=C(C=C3/C/2=N\O)C(O)=O)C2=C1C(Br)=CC=C2
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C(ON=C1[H])C([H])([H])[H]
[H]\C(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C1/C(=O)C2=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C(=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C2C(=NC(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)N([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(SC2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])C([H])([H])[C@@](O[H])(C#CC4=C(N([H])C5=C4C([H])=C([H])C([H])=C5[H])C4=C(OC([H])([H])[H])C([H])=C([H])C([H])=C4[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
[H]N(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])[C@@]1([H])[C@@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC(=O)[C@@]1(OC2=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC3=C(Cl)C([H])=C(C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2N([H])N=C(C3=C([H])C4=C(N3[H])C([H])=C(C([H])=C4[H])C([H])([H])[H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])N([H])C(=O)C1=C(N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C2OC([H])([H])C([H])([H])OC2=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C2=C1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(C1=C([H])N=C(S1)N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=NC([H])=C([H])N1C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]C([H])([H])C1(C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C([H])C([H])=C([H])C(Cl)=C4Cl)C([H])([H])C3([H])[H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])OC1=C(C([H])=C(C([H])=C1C([H])([H])[H])C(=O)O[H])C([H])([H])[H]
ClC1=C(Cl)C(=CC=C1)N1CCN(CCCCNS(=O)(=O)C2=CN=CC3=CC=CC=C23)CC1
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[H]C1=C([H])C([H])=C2N=C(SC2=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C(=NO1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N=NN1C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C([H])C2=C([H])C3=[N+](C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C31)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])O1)[C@@]1([H])OC(=O)[C@]2([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@]3([H])[C@@]2(C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1N([H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C(SC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C(=C2C3=C(C([H])=C([H])C([H])=N3)C([H])([H])S(=O)(=O)C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N(C([H])([H])C3=C([H])C([H])=C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2=C1[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)[C@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1(N2C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C3=C([H])C([H])=C([H])S3)C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]OC([H])([H])C#CC([H])([H])OC1=NC(=NC(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1OC1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])[C@@]1([H])C2=C([H])C(OC(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=O)C(=O)C2=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]OC1=C([H])C(Cl)=C(C([H])=C1[C@]1([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]1([H])O[H])C([H])([H])C1=NC([H])=C(S1)C1=C([H])C([H])=C([H])O1
[H]N(C1=NC(=C([H])C([H])=N1)[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C(F)C([H])=C3[H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)C(SC([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C2([H])[H])C([H])([H])N([H])[C@@]([H])(C([H])([H])N([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)C1=NN=C(O1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])O[H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C(N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C2C([H])=C1C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])N([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])SC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=C(\F)C(=O)N([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H])\C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(F)C(O[H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(S1)C(=O)C([H])([H])SC(=S)SC([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=NC([H])=C(C2=NC(=C3N2C2=C([H])C(F)=C([H])C(OC([H])([H])[H])=C2N=C3C([H])([H])[H])C([H])([H])[H])C(=C1[H])C([H])([H])[H]
O=C1C=C(OC2=C1SC=C2C1=CC2=C(N1)C=CC=C2)N1CCOCC1
[H]N([H])C1=NC([H])=C(N([H])C(=O)C2=C(C([H])=C([H])C(N([H])C(=O)C3=C([H])C(=C([H])C([H])=C3[H])C(F)(F)F)=C2[H])C([H])([H])[H])C([H])=N1
[H]N(\N=C(/C1=C([H])C([H])=C([H])S1)C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]C1=C(C([H])=C(N1C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N(C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C(O[H])C([H])=C2OC(=C(C3=C([H])N(N=N3)C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C3=C4C([H])=C([H])C([H])=C([H])C4=C(C([H])=C3[H])[N+]([O-])=O)C2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2=O)C1=C([H])C([H])=C(O[H])C([H])=C1[N+]([O-])=O
[H]C1=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])[C@]2([H])C([H])([H])C([H])([H])[C@]3(C(=O)C([H])([H])C([H])([H])[C@@]3([H])[C@@]2([H])C1=O)C([H])([H])[H]
[H]N([H])C1=C(OC([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)N=C(C([H])=N1)C1=C([H])N(N=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C(C([H])=C1[H])C1=NOC(=N1)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(Cl)=C(F)C([H])=C1[H])C1=NC([H])=NC2=C1SC(=N2)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])N2C(=N1)C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])S(=O)(=O)C2=C([H])C3=C([H])C([H])=C(Cl)C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC(=NC(=C1[H])C1=NC([H])=C([H])S1)N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
CN(C)CCCOC1=CC=CC=C2C(\C=C3\C(=O)NC4=C(F)C=CC=C34)=CC(C)=C12
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(SC3=C(C([H])=C([H])C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=NN1C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])N12
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])[C@]2([H])C(=O)N(C3=C([H])C([H])=C(OC([H])([H])C(F)(F)F)C([H])=C3[H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C(N([H])C2=NC([H])=NC3=C2N([H])C([H])([H])C2=C(O3)C([H])=C(C([H])=C2[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=N1
[H]N(C1=C2C([H])=NN(C2=NC(SC([H])([H])[H])=N1)C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])[C@@]4([H])[C@@]5([H])C([H])([H])C([H])([H])C([H])([H])[C@@]4(C([H])([H])C([H])([H])[C@]5([H])O[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])\N=C(\N([H])[H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C(Cl)=C(F)C([H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])N=C(N([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C12
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(N([H])C([H])([H])[H])C(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
CC1=CN=C(CNCC2(F)CCN(CC2)C(=O)C2=COC3=C2C=CC=C3)C=C1
[H]N1C([H])([H])[C@@]([H])(N2C3=C(C([H])=C(C([H])=C3[H])[N+]([O-])=O)C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]OP(=O)(O[H])C(F)(F)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(N1N=NC2=C1C([H])=C([H])C([H])=C2[H])(C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)P(=O)(O[H])O[H]
[H]N([H])C1=C(C(=NN1C([H])([H])C([H])([H])[H])C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(N=C(S2)N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N=C1N([H])\C(=C(\[H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3Br)C(=O)N1C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C(=N1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@]1([H])[C@]33C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]([H])(C2([H])[H])[C@]32C([H])=C([H])[C@@]1(O[H])[C@]([H])(C2([H])[H])[C@](O[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C2=C([H])C(OC3([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C12)C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C([H])=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])C1=NC2=C([H])C([H])=C([H])N=C2N1C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(O[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(\[H])=C(\[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
C[C@H](CO)NC1=C(Br)C=NC(NC2=CC=C(C=C2)S(C)(=O)=NS(=O)(=O)CC[Si](C)(C)C)=N1
[H]C1=NC2=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C(Cl)=C1[H])C2=C1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
CCOC(=O)C1=CC2=CC=C(OCCN3CCCCC3)C=C2OC1=O
[H]N1C(=O)C([H])=C(C2=C1C([H])=C(C([H])=C2[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=NC(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C([H])([H])C([H])([H])N2C([H])([H])[C@]3([H])C([H])([H])N(C(=O)C4=C(N=C(N=C4C([H])([H])[H])C(F)(F)F)C([H])([H])[H])C([H])([H])[C@]3([H])C2([H])[H])C([H])([H])N(C(=O)C2([H])C([H])([H])C(F)(F)C2([H])[H])C1([H])[H]
[H]C1=C([H])C(C2=NN(C3=C2N=C(C([H])=C3N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C2([H])[H]
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C([H])=C(C([H])=C2[H])N2C(=O)C3=C(C(=NN3C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C(=O)N([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1C([H])=C(F)C(F)=C2[H])C(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])=C1C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)[C@]2([H])ON(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[N+]([O-])=O)[C@]2([H])C1=O
[H]N(C(=O)C1=C([H])N(C2=C(N=C([H])C([H])=C2[H])C1=O)C([H])([H])[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C(F)(F)F
[H]N1N=NC(=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C3N(C([H])=C([H])C3=C2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=NC2=NC([H])=C(C([H])=C12)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C2=C1N=C([H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C(F)C(=C([H])C([H])=C12)C1=C(F)C([H])=C(C([H])=C1[H])C1=C(C([H])=NC([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2ON=C(N([H])[H])C2=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])[C@]([H])(OC(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(=C([H])C(=C1[H])C(=O)OC([H])([H])[H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@@]1([H])N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CCCC[C@@H](C)NC(=O)C1=NC2=C(NS(C)(=O)=O)C=CC=C2C(O)=C1
[H]N([H])C1=NC2=C(C(=C(SC3=C([H])C([H])=C([H])C(Cl)=C3[H])N2[H])C([H])([H])C([H])([H])[H])C(=N1)N([H])[H]
[H]O[C@]([H])([C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(C2=NC(=C3N2C([H])=C([H])N=C3N([H])[H])C2=C([H])C([H])=C(C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C(OC([H])([H])[H])=C2[H])C1([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C(OC([H])([H])[H])=C(C#N)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(/[H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C2[H])C1=O
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C(S1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C(F)(F)F)C(=C1[H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C2(C([H])([H])N(C3=C([H])C([H])=C4N=NN(C4=N3)C3=C([H])C([H])=C([H])C(OC(F)(F)F)=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@]1([H])N(C(=NC2=C([H])C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
CCC1=CC(=CC=C1)C(CCCN)(C1=CC=CC=C1)C1=CC=CC=C1
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(O2)C(=O)C2=C(O1)C([H])=C([H])C(O[H])=C2[H]
[H]N([H])C1=NC2=C(C(SC3=C([H])C([H])=C([H])C([H])=C3[H])=C(S2)C([H])([H])[H])C(=O)N1[H]
[H]OC1=C(C([H])=NC2=NC([H])=C([H])C([H])=C12)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=NN(N=C1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C(=O)N(C([H])([H])[H])[C@@]1([H])C([H])([H])[C@]2([H])O[C@](N3C4=C(C([H])=C([H])C([H])=C4[H])C4=C5C(C(=O)N([H])C5([H])[H])=C5C6=C(C([H])=C([H])C([H])=C6[H])N2C5=C34)(C([H])([H])[H])[C@@]1([H])OC([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[C@]([H])(OC2=C(C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])O2)C([H])([H])[H])C([H])=C1C([H])([H])[H]
CS(=O)(=O)NC1=C2N=C(C=C(O)C2=CC=C1)C(=O)NC1=CC=C(F)C=C1F
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C(=C1C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(S[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(S[H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C2=C(N=C([H])N2C([H])([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]1([H])O[C@]2(O[C@](C(=O)O[H])([C@]([H])(O[H])[C@@]2([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1(O[H])C(=O)O[H])C([H])([H])C([H])([H])C(=C([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([C@]([H])(C1=NC([H])=C(N1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C(=O)N([H])S1(=O)=O)S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
CN1N=C(C2CCCCC2)C2=C3C=CNC3=NC=C12
CCCN(CCCCOC1=CC=C(CC2=CC(=CC=C2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C=C1)C(=O)CCC1=[N+]2C(C=C1)=CC1=C(C)C=C(C)N1[B-]2(F)F
[H]C1=C(OC([H])([H])[H])C([H])=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C1OC1=C(OC2=O)C([H])=C(OC([H])([H])[H])C(C(=O)OC([H])([H])[H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(SC2=NN=C([H])N2C([H])([H])[H])C([H])=C1C(=O)N([H])C1=NC([H])=C(S1)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])C([H])([H])C1=C(N=C(N=C1[H])N([H])[H])N([H])[H]
[H]N([H])C1=NN([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])C(=NC(=N1)N([H])[H])N1C([H])([H])C([H])([H])O[C@@]([H])(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C(Cl)C([H])=C(\C([H])=C2/C(=O)C3=C([H])C([H])=C(N([H])[H])C([H])=C3C2=O)C([H])=C1Cl
[H]N(C1=NC2=C(N=C(N=C2[H])N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])N1C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])[C@]([H])(N2C([H])([H])C3=NN=C(N3C([H])([H])C2([H])[H])C(F)(F)F)C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C(F)=C(F)C([H])=C1F
[H]N(C(=O)[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F)C([H])([H])C1=NC2=C([H])C([H])=C([H])N=C2N1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(O1)C([H])([H])N(C(=O)N1OC(=O)C(=C1C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O\N=C(/[H])C1=C([H])C([H])=C(O[C@]2([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]2([H])O[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])C4=C(C5=C(N4[H])C(OC4=C([H])C([H])=C([H])C([H])=C4[H])=C([H])C([H])=C5[H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC(=NC(=C1[H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(O1)C([H])([H])[H]
CCC1=C(CC)CC2=C(CC(C2)NC[C@H](O)C2=C3C=CC(=O)NC3=C(O)C=C2)C1
[H]N(C1=NN2C(=NC(=C2C([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
CC(C)CC(N1C(C)=CC(=CC1=O)S(=O)(=O)C1CCCC1)C(=O)NC1=NC=CS1
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(SC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])[S@@](=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C(=O)O[H])C(=O)O[H]
[H]OC(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C(C(=NN2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC1=NN([H])C(=N1)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N([H])C(=O)C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])[S@@]1=O
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OP(=O)(O[H])O[H])C([H])=C1[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C(=O)O[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C1=C([H])C([H])=C(OP(=O)(O[H])O[H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N2C(=O)C([H])([H])N(C(=O)C([H])([H])C([H])([H])C3=NC([H])=C([H])C([H])=C3[H])C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])C(=O)C1=NC([H])=C([H])S1
[H]N(C1=C([H])C([H])=C([H])C([H])=C1F)C1([H])C([H])([H])C([H])([H])N(C(=O)C2=NC([H])=C([H])C([H])=C2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])[C@@]([H])(N([H])[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(N2C([H])=NC(=C2C2=C([H])C([H])=NC(OC3=C([H])C([H])=C(F)C(F)=C3[H])=N2)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]([H])(OC(=O)[C@]1([H])N(C(=O)C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]C1=C([H])C([H])=C(OC2=C(OC(=C([H])C2=O)C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C#CC1=C(OC([H])([H])C([H])([H])[H])N=C(C([H])=C1N([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])\C(=C(\C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N(C2=C([H])C(=C([H])C([H])=C12)C1=C(ON=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]OC1=C([H])C([H])=C2C(OC(=O)C([H])=C2C([H])([H])SC2=C([H])C([H])=C(C([H])=N2)[N+]([O-])=O)=C1[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])[H])S(=O)(=O)C2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C2C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])N(C(=O)C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C(=O)C([H])([H])SC1=NN=C(N1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]ON(C([H])=O)[C@@]([H])(C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=NC([H])=C([H])S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=NN2C([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C(=C12)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
FC1=C(OCCCN2CCN(CC2)C2=CC=CC3=CC=CC(F)=C23)C=C2C(=O)NCC2=C1
[H]N=C(N([H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=C([H])S2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]N1C([H])([H])C2=C([H])C(I)=C([H])C([H])=C2C([H])([H])[C@]1([H])C(F)(F)F
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C(Cl)=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C1=NN2C(SC1([H])[H])=NN=C2C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C(=O)O[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])[H])N([H])[H]
IC1=CC=C(CN2C=CN=C2)C2=C1OC1=CC=CC=C1C2=O
[H]N1C(=NC(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(OC2=NN=C(C3=C2C([H])=NN3C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C([H])([H])[C@]12C(=O)C([H])([H])[C@]([H])(C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C(=C1[H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)C([H])([H])SC([H])([H])C1=C(F)C([H])=C([H])C([H])=C1Cl)C([H])([H])C(=O)O[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(N(C(=O)C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@]([H])(N([H])C(=O)C1(N4C([H])([H])C([H])([H])N(C5=C([H])C([H])=C(C([H])=N5)C(F)(F)F)C([H])([H])C4([H])[H])C([H])([H])C1([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
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[H]N([H])C1=C2C([H])=C(C([H])=C([H])C2=NN1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])C([H])([H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[C@]1([H])O[C@]2([H])C3=C([H])C(=C([H])C([H])=C3N([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]2([H])C([H])([H])C1([H])[H])C(F)(F)F
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[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])C([H])([H])N2C3=C([H])C([H])=C(C([H])=C3C3=C2C2=C(C4=C(C([H])=C([H])C([H])=C4[H])N2C1([H])[H])C1=C3C([H])([H])N([H])C1=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C([H])C2=C(C([H])=C1[H])C(O[H])=C([H])C(=N2)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(\N=N\C2=C(O[H])C([H])=C(C3=C2C([H])=C([H])C([H])=C3[H])S(=O)(=O)O[H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])N([H])[H]
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[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
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[H]O[C@]([H])(C([H])([H])N1N=C(C2=C1C([H])([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(C#CC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C(Cl)C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)N([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C2\C(=C(/[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]
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[H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C(F)(F)F
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[H]OC1=C([H])C(N([H])C(=O)C([H])([H])N2N=C(C3=C([H])C([H])=C([H])C([H])=C3N(C2=O)C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
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[H]OC(=O)[C@]([H])(O[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)N([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2N=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC(=O)C2=C([H])C(Cl)=C(N([H])[H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)P(=O)(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(C2=C1C(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C(C([H])=N2)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=NC([H])=C(O1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
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[H]N([H])C(=O)C1=C([H])N=C2C(C([H])=C([H])C([H])=C2C(F)(F)F)=C1C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])[C@]([H])(O[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@@]1(O[H])C([H])([H])[H])C([H])([H])OC(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C1=C(C(=O)OC([H])([H])[H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C(C([H])=C(Br)C([H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C1=O
[H]SC([H])([H])[C@]([H])([N+]([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C(=O)N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])C2=C(N(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C2=C([H])C(=NC(=N2)N2C([H])=NC([H])=C2[H])C([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(C(=O)OC1=C([H])C([H])=C2N(C([H])([H])[H])[C@]3([H])N(C([H])([H])C2=C1[H])C([H])([H])C([H])([H])C1=C3C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])S1)C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O
[H]C1=NC(OC2=C([H])C([H])=C([H])C([H])=C2[H])=NC(=C1[H])C1=NN2C(OC([H])([H])C2([H])[H])=C1C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C(=O)C([H])=C(C2=C1C([H])=C1OC([H])([H])C([H])([H])N([H])C1=C2[H])C(F)(F)F
[H]N(C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C1=NC(=NS1)N1C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=NO1)C1=C(N=C([H])C([H])=C1[H])N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@@](C#N)(C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(OC([H])([H])C(=O)O[H])C(Br)=C(S1)C1=C([H])C(N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N1C(=O)S\C(=C(\[H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C1=O
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=NC(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)C(=O)C([H])([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=O)N2C([H])([H])[C@]([H])(O[C@@]([H])(C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C(F)C([H])=C3[H])[C@]2([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(N([H])C(=O)C2=C(OC([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C1=C([H])C2=C(C([H])=C1[H])C(=NN(C2=O)C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C1=C([H])C(=NN1[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])OC(=O)C2=C([H])C(Cl)=C(N([H])[H])C([H])=C2OC([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])N2C(SC3=C([H])C([H])=C(Cl)C([H])=C3[C@]([H])(N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H])=C1[H]
[H]N([H])C1=NC([H])=C([H])C([H])=C1C1=NC2=C([H])C(Br)=C([H])N=C2N1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=NC2=C([H])C(Cl)=C(C([H])=C2C(OC([H])([H])C([H])([H])[C@]2([H])OC([H])([H])C2([H])[H])=C1C1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=NSN=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])[C@]1([H])C2=C([H])C(=C([H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]OC1=C2O[C@@]3([H])C4=C(C5=C(N4[H])C([H])=C([H])C(=C5[H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]ON([H])C(=O)C([H])([H])N(OC([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C(\[H])=C(/[H])C3=C([H])C([H])=C(C([H])=N3)C3=C([H])C([H])=C([H])C(F)=C3[H])[C@]3([H])[C@]([H])(OC(=O)[C@]3([H])C([H])([H])[C@]2([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]1([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])\C([H])=C([H])/C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=C([H])C3=C(C([H])=C2[H])C([H])=C(O[H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)C1=C(OC([H])([H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2O[C@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(C1=C([H])C(=C([H])C([H])=N1)C1=NC(=C([H])S1)C1=C([H])C(C(=O)OC([H])([H])C([H])([H])[H])=C(N([H])C1=O)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C3=C(SC(C([H])=C3C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C([H])=C1Cl)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]2(C([H])=C(C3=NC([H])([H])C([H])([H])N3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C2C3=C1C(=C([H])C([H])=C3[C@@]1([H])C([H])([H])[C@@]([H])(C([H])([H])N3C(=O)N([H])C(=O)C3([H])[H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C2N=C(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C2=NC([H])=N1
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])N=C([H])C(=C1[H])C1=C([H])C2=C(N([H])C(=O)C2([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@]([H])(C([H])([H])OC2=C(OC([H])([H])[H])C([H])=C(I)C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@](C#N)(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C([H])([H])[H])C([H])([H])[C@]1(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[C@@]([H])(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC1=O)C([H])([H])Br
[H]N([H])[C@]([H])(C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1F)[C@]([H])(C1=NC(=NO1)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C2N(C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H])C1=NC(=NC2=C1N(N=C2C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C(F)(F)F)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1N=NC(=N1)C([H])([H])C([H])([H])N1N=C(C2=C1N=C(C([H])=C2C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])C1=NN(C(=O)N(C([H])([H])[H])C([H])([H])[H])C(SC([H])([H])[H])=N1
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C(=C23)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C(\C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])=C(\C([O-])=O)C1=C([H])C2=NSN=C2C([H])=C1[H]
[H]N([H])C1=C(I)C([H])=C(C([H])=C1[H])[C@@]([H])(C(=O)OC([H])([H])[H])[C@]1([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C([H])([H])C([H])([H])OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C(=O)C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])C(=O)C([H])([H])C1=C(SC([H])([H])[H])N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2O[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=NN2C([H])=C(C3=NN=C(O3)C([H])([H])C([H])([H])[H])C(=C12)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(N=C1[H])N([H])C(=C2[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C2N=C(N([H])C([H])([H])[H])C([H])=C([H])C2=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=NC2=C1N=C(Br)N2C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]1([H])[C@]([H])(O[C@@]([H])(N2C([H])=NC3=C(N=C(Cl)N=C23)N([H])[C@]2([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C3([H])[H])[C@@]1(O[H])C([H])([H])[H])C([H])([H])SC1=C(F)C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(\C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])=C1/C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C(=O)C1=C([H])C([H])=C(Cl)C(N([H])[H])=C1[H]
CN1C=C(C(=O)N(C)C1=O)C1=CC=C(C[C@H](NC(=O)C2=C(Cl)C=CC=C2Cl)C(O)=O)C=C1C
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C([H])=C([H])C(=C([H])C2=C([H])C([H])=N1)C([H])([H])[C@@]([H])(N([H])C(=O)N([H])N([H])S(=O)(=O)C1=C(C(=C2OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(F)=C1N([H])C1=C([H])C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=NC([H])=C1C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=N1)[C@]([H])(C1=C(C(=O)C(=C(C1=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(=N\OC([H])([H])[H])\C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])N=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C(N([H])N=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1Cl
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(=C(OC2=C([H])C3=C(N([H])C([H])=C3C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3C([H])([H])C([H])([H])[C@]12[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC(=O)C2(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1O[C@@]1([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1([H])[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C([H])C(=N1)C([H])([H])SC1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]C1=C([H])C2=C(C([H])=C1C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C1(C2=NN=C3N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C3=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C(F)=C1[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C([H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C2([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(F)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(F)=C(C([H])=C1F)[C@@]1(C([H])([H])C([H])([H])C(=O)[C@@]([H])(C(=O)OC([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(N3C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C3([H])[H])=C(N([H])C(=O)C3=C([H])C([H])=C(O3)C#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C2C([H])=C([H])C([H])=NN2N=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NC2=C(N=C(C(=O)N2[C@@]([H])(C([H])([H])C([H])([H])[H])C2([H])C([H])([H])C2([H])[H])C([H])([H])[H])C(=C1[H])C1=C([H])C([H])=C(OC([H])(F)F)C([H])=C1Cl
[H]N1C(=O)C(=C([H])C(C(=O)OC([H])([H])C([H])([H])[H])=C1C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])SC(=N1)C([H])([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C2N(C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NN=C(\C1=N/N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
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[H]N1C([H])=C(C2=C1N=C([H])C([H])=C2[H])C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C3=C2OC([H])([H])C([H])([H])O3)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C1=C([H])N([H])C([H])=N1
[H]N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C1=C2N=C([H])C([H])=C(C2=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])N(C([H])([H])[H])C([H])([H])[H])C2([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]SC([H])([H])[C@]([H])(N([H])[H])C([H])([H])N([H])C1=C([H])C([H])=C(OC2=C([H])C(=C([H])C([H])=C2[H])C(=O)OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC([H])([H])C(=O)C(F)(F)F)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])(C(=O)O[H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C(=O)O[H])C(=O)O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])(C(=O)O[H])C(=O)O[H])C([H])([H])C(=O)O[H]
[H]OC1=C([H])C([H])=C(N([H])C(=O)[C@@]2([H])C3=C([H])C(O[H])=C([H])C([H])=C3C(=C2C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=N\N([H])C2=NC(=C([H])S2)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3OC2=O)C([H])=C1OC([H])([H])[H]
[H]C1=C(C(=NN1C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C(=N2)C#N)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C1=NC(=NC(=N1)N(C([H])([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])[H])N([H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C([H])=C(OC2=NC([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2N=C1C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(N([H])C(=O)C2=C(OC([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])[N+]([O-])=O)C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N(C1=NC(=C([H])C([H])=N1)N(C(=O)C1=C([H])C2=C(OC([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C2C([H])=C(N([H])C2=N1)C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])N(C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]2([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])S1(=O)=O
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=N1)C1=C([H])C2=C(N=C([H])N([H])C2=O)N1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)S[C@@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=N2)C(F)(F)F)C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])[C@]2([H])C([H])([H])[C@@]3([H])N(C(=O)OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4Cl)[C@]2([H])C([H])([H])C3([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
COC1=CC=C(C=C1)C1=NN2C(=C1)C1=C(NC2=O)C=CC=C1
[H]N(C(=O)C1=NN2C(N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C23)=C1[H])C([H])([H])C([H])([H])C1(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C(=O)N([H])C1=C(C(=O)O[H])C2=C(S1)C([H])([H])[C@]([H])(O[H])C([H])([H])C2([H])[H]
[H]C1=C(SC(=C1[H])C1=NC(=NO1)C1=C([H])C([H])=C([H])N=C1[H])C(=O)C(F)(F)F
[H]C([H])=C([H])C([H])([H])C([H])([H])N1C(=O)N(C2=C(N([H])C([H])=N2)C1=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])O[H]
[H]OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=NC([H])=NC(N([H])C3=NN([H])C(=C3[H])C([H])([H])C(=O)N([H])C3=C([H])C(F)=C([H])C([H])=C3[H])=C2C([H])=C1OC([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C(F)C([H])=C1[H])C([H])([H])N1C(=O)[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C(S2)C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(N3C(=N2)C([H])([H])[C@]([H])(C2=C(F)C([H])=C(F)C(F)=C2[H])[C@@]([H])([N+]([H])([H])[H])C3([H])[H])[N+]([H])=C1[H]
[H]OC1(C(=O)N2C([H])([H])C([H])([H])C([H])(C(=O)N3C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C4=C([H])C([H])=C(C([H])=C4[H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C([H])([H])[H])[C@]([H])(C4=C([H])C([H])=C(Cl)C(Cl)=C4[H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=NN(C2=C1C([H])([H])[C@]1(C(=C2[H])C([H])([H])C([H])([H])N(C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C([H])([H])C1(C2=C([H])C([H])=C(N([H])C3=NC4=C(C([H])=C(C([H])=C4N=N3)C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C(S1)S(=O)(=O)N1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3F)C2([H])[H])C([H])([H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(=C2N([H])N=C([H])C2=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])[P@@](=O)(OC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
CC1=NC=C(N1CCOC(=O)\C=C\C1=CC=C(Br)C=C1)N(O)=O
[H]N([H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])N1N=C(C2=C1C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(S[H])[C@]([H])([N+]([H])([H])[H])C([H])([H])C([H])([H])C([O-])=O)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)O[H]
[H]N(C1=NC([H])=C([H])C([H])=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N([H])[C@@]([H])(C(=O)[N+]1=NC([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])N=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]2(C([H])([H])OC2([H])[H])[C@@]([H])(O[H])[C@]1([H])O[H])C1=C([H])C([H])=C(Cl)C(=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=NC2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C([H])([H])C(=O)N1[C@]([H])(C(=O)N(C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C(F)(F)F)C([H])([H])S(=O)(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])N2C(=C1[H])C(=O)[C@]([H])(SC1=C([H])C([H])=C([H])C([H])=C21)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=N[C@]([H])(C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C2=C1SC([H])=C2[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(OC2=C([H])C([H])=C([H])C3=C([H])C([H])=C(N=C23)C2=NN=C3C([H])=C(Cl)C([H])=C([H])N23)[C@]([H])(F)C1([H])[H]
[H]N(C(=O)OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(C(=O)OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C2=C([H])C(Cl)=C([H])C3=C2N(C2=C3C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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