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[H]C1=C(N=C2N1C([H])=C([H])C([H])=C2C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C(=C3N=C2[H])C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1F)C([H])([H])[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2S1)C1=NN([H])N=N1
[H]N1C(=O)C(=O)C2=C1C(Cl)=C([H])C(Cl)=C2[H]
[H]OC(=O)[C@]([H])(OC1=C(C#N)C([H])=C([H])C(OC([H])([H])C2=C([H])SC([H])=C2[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1OC1=C([H])C([H])=C(F)C(=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[C@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1O2)C([H])([H])[H]
[H]N([H])C1=NC(=C(S1)C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C([H])=C(C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1(C2=NN=C(N2C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(OC2=C(C([H])=C([H])C(OC3=C([H])C(=C([H])C([H])=C3[H])C(=N[H])N([H])[H])=N2)C(=O)N([H])[H])=C([H])C([H])=C1[H]
[H]N1C(OC([H])([H])C2=C(ON=C2C([H])([H])C([H])([H])[H])C([H])([H])[H])=NC2=C(C1=O)C(=C([H])C(=O)O2)C([H])([H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C(OC([H])([H])[H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])(N3C(=O)OC([H])([H])C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])[C@]([H])(C(=O)OC([H])([H])[H])C1([H])[H]
[H]OC([H])([H])C1=C(OC2=C([H])C([H])=C3N=C([H])N=C(N([H])C4=NN(C([H])=C4[H])C([H])([H])[H])C3=C2[H])N=C([H])C([H])=C1[H]
[H]N(C1=C2C(=NC([H])=N1)N([H])C(=O)\C2=C(\[H])C1=C(C([H])=C(N1[H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1Br)C([H])([H])C([H])([H])OC(=O)[C@]1([H])[C@]2([H])N(C([H])([H])[H])C([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C2=C(N([H])C(=C2[H])C2=NC(=C([H])N=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C2C([H])=C([H])N([H])C2=C([H])C([H])=C1[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C1=C([H])C3=C(S1)C([H])=C([H])C([H])=C3[H])C2([H])[H]
[H]N1C([H])=C(N2C(Cl)=C(Cl)C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N=C1N(C2=C([H])C([H])=C([H])C(Cl)=C2N1C([H])([H])C([H])([H])C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC3=C(N=C([H])N3C([H])(C([H])([H])[H])C([H])([H])[H])C(=N2)N([H])C([H])([H])C2=C([H])C([H])=C(S2)C2=C([H])C([H])=C([H])O2)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N=C1Cl)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])N=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C(OC(=N1)C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C([H])=C([H])C(OC2=C([H])C([H])=C(F)C([H])=C2[H])=N1)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OS(=O)(=O)C(F)(F)F)=C2C(=C1[H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C(=C(Cl)C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C([H])C(=C1[H])C1=NN2C(S1)=NN=C2C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(OC2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])C2=C1N=C(N(C2=O)C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C2=C(C3=C([H])C([H])=C([H])C([H])=C3N2S(=O)(=O)C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(C(=O)N([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C(Cl)C([H])=C1C([H])([H])C([H])([H])[H]
CC1(C)C2CC1[C@]1(C)OB(O[C@@H]1C2)C(CC1=CC=CC=C1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC1=CC=CC=C1)NC(=O)OCC1=CC=CC=C1
[H]N(C(=O)C1=C([H])C([H])=C(C(=C1[H])N1C([H])=NC2=C(C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1=O)C([H])([H])[H])C1=NN=C([H])S1
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C([H])N([H])C4=C([H])C([H])=C([H])C(=C34)[C@@]2([H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(N1[H])C([H])=C(F)C(=C2[H])C(N([H])[H])=[N+]([H])[H]
[H]O\C(=C(\C#N)C(=O)N([H])C1=C([H])C([H])=C(C(=C1[H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(S2)C2=C([H])N=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]C1=C(N(C2=NC(=NC(=N2)C([H])([H])[H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(Br)=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
CC1=C(C)N(CCO[11CH3])\C(S1)=N\C(=O)C1C(C)(C)C1(C)C
[H]C1=NC(Cl)=C(C([H])=C1[H])[C@@]([H])(OC1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])C(F)(F)C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C(C([H])=C2N(C([H])=NC2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC([H])=C([H])N1[H])C1=C(C(OC([H])([H])[H])=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C1=NN(C2=C1C([H])([H])C1=C2C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)[C@@]2([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@@]11C([H])([H])N(C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])C2=C(C3=C(C([H])=C(F)C([H])=C3N2C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1F)N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)N([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])C#C[H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)[C@@]([H])(N1C(=O)C2=C([H])C(I)=C([H])C([H])=C2N(C(=O)[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])N([H])[H]
[H]O[C@]1([H])[C@]([H])(O[H])[C@]2(C(=O)N([H])C([H])([H])[H])C([H])([H])[C@]2([H])[C@@]1([H])N1C([H])=NC2=C1N=C(N=C2N([H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C#CC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C(C#N)=C2[H])[C@]1([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]C1=NC(=NC([H])=C1[H])N1C(=O)N(C(=O)C11C([H])([H])C([H])([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=N2)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=NS2)C2=C([H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(N([H])C(=C2C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C2=C3C(=C([H])C([H])=C(OC4=C([H])C([H])=C([H])C(=C4[H])C([H])([H])[H])C3=C1[H])C1=C(C#N)C(=O)N=C21
[H]ON([H])C(=O)[C@]([H])(N1C(=O)[C@@](C2=C([H])C([H])=C(OC([H])([H])C([H])=C([H])[H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C([H])([H])C2=C([H])C(O[H])=C([H])C([H])=C2O[H])=C([H])C([H])=C1O[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3C([H])([H])C2([H])[H])=C1[H]
[H]N1C(=O)N([H])C(=O)C(N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(I)C([H])=C3[H])C([H])([H])C2([H])[H])(C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(F)=C1[H])S(=O)(=O)C1(F)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])C1([H])[H]
[H]N1C(=C(N2C([H])=C(Cl)C([H])=C([H])[C@]12[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
CCC1=NN2C(C=CC=C2C2=C(C)C=C(C)C=C2OC)=C1N(CC1CC1)CC1CCOCC1
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@]1([H])C([H])([H])O[C@]([H])(O[C@@]1([H])C1=C([H])N=C([H])C([H])=C1[H])C(OC1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(Cl)C2=C(N=C1[H])N(N=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(O[H])[C@]([H])(C(=O)N([H])[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])N2C(=NC(=C(C(=O)OC([H])([H])[H])[C@]2([H])C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C([H])([H])C([H])([H])\C3=N\C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(C(=C2N1C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N(C1=C([H])C(F)=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2(C3=C([H])C(F)=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C(=O)C3=C([H])C(=C(F)C([H])=C3Cl)S(=O)(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C(=O)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]N1N=C2N(C1=S)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N2C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=[N+]([O-])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])S1)C1=C([H])C(=C([H])C([H])=C1F)C(F)(F)F
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(=C2[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)S(=O)(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])N(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1Cl)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC1=C([H])C2=C(C(=O)[C@]([H])(C2([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(C([H])([H])O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C([H])([H])[C@]([H])(N2C(=O)C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC([H])([H])[C@]1([H])C([H])([H])N2C3=C([H])C([H])=C([H])C([H])=C3C3=C2C2=C(C4=C(C([H])=C([H])C(\C([H])=C(/[H])C([H])([H])N([H])C5=NC([H])([H])C([H])([H])N5[H])=C4[H])N2C1([H])[H])C1=C3C([H])([H])N([H])C1=O
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])C([H])([H])C2=C1C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C3(N(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])N(C3=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])=C2[H]
[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=NN=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C2=NN=C3SC(=NN23)C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C1=C([H])C(=NC([H])=N1)N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])N([H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C(=O)N([H])C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]N(C(=S)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN=C(S1)N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]\C(=C(/C1=NC(=NO1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C2=C([H])C([H])=C([H])N=C12)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C1=NC(=C(N21)C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C(F)(F)F)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(I)C([H])=C1[H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N([H])C1=NC2=C(O1)C([H])=C(C([H])=C2[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])N(C3=C([H])N=C(Cl)C([H])=C3[H])[C@@]2([H])C1([H])[H]
COC1=C(OCCCCSC2=CC3=CC=CC=C3C=C2)C2=C[N]3=C(C=C2C=C1)C1=CC2=C(OCO2)C=C1CC3
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C(C#N)=C2[H])C([H])=C1[H]
CC(C)(C)C(=O)NC1=CC=CC(OC2=NN3C=C(NC(=O)C4CC4)N=C3C=C2)=C1
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N=C1[H])N([H])\N=C1\C2=C(N([H])C3=C2C([H])=C(F)C([H])=C3[H])C(=O)N([H])C([H])([H])C1([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C2C([H])=C([H])C([H])=C([H])C2=NC(=C1[H])C([H])([H])C([H])([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C([H])=C2[H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])([H])C([H])([H])N1[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])[N+]([O-])=O)C([H])([H])[H]
[H]N(C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N1C(=N[H])C([H])=C([H])C2=C1C([H])=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(C([H])=C1[H])C1(N([H])[H])C([H])([H])C(F)(F)C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@]([H])(N([H])C(=O)C(OC1=C([H])C([H])=C([H])C(Cl)=C1[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]C1=NC(OC2=C(C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])[H])C(OC2=O)(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1C1([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])([H])N(C1=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C(=N1)C([H])([H])Cl
[H]N1C([H])([H])C([H])([H])O[C@]([H])(C1([H])[H])[C@]([H])(OC1=C(OC([H])([H])[H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]C1=NC(F)=C(C([H])=C1[H])[C@]1([H])C([H])([H])C2=C(N=NC2=C2N=NN=N2)C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=NC2=C([H])C([H])=C(N([H])C(=O)C([H])([H])[N+]3=C(C([H])=C(C([H])=C3C([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])=C2S1
[H]N(C(=O)C1=C(N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(C#N)(C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2N(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=N1)C(F)(F)F)C([H])([H])[C@@]1([H])N(C(=O)C2=C(SC(=N2)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]([H])(F)C([H])([H])C1([H])[H]
[H]N(N([H])C(=O)C([H])([H])SC1=NN=C(N1N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C(N([H])C3=C([H])C([H])([H])C([H])([H])C([H])([H])N3[H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])N([H])C2=C(C([H])=C(C([H])=C2[H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])N(C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=O)C(=C(C(=O)OC([H])([H])C([H])([H])[H])C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NN(C(=N1)N([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C2O[C@@]3([H])[C@]([H])(OC([H])([H])[C@@]4([H])OC4([H])[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N1C(=O)C([H])([H])N(C2=NC(=C([H])C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C12)C([H])([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1Cl
[H]N(C(=O)C1=NC2=C(C([H])=C(F)C([H])=C2C(OC([H])([H])[H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])N(C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])S1(=O)=O
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=C([H])C2=C1C(=C([H])C(=C2[H])C(=O)N1C([H])([H])C([H])([H])C2(OC3=C(C(OC([H])(C([H])([H])[H])C([H])([H])[H])=NC([H])=C3[H])C(=O)C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)\N=C1/SC(C(=O)OC([H])([H])C([H])([H])[H])=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC(=O)C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C(N=C1[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])[H]
[H]N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])C1=NC(N([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[H])=C([H])C([H])=N1
[H]O[C@]([H])(C(\[H])=C(/[H])C(N1N=NN=C1[H])=C(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C(C(=NN1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
CC(C)(C)C(=O)NC1=NC(NC2=CC=C(F)C(Br)=C2)=C2C=C(CCC3=NC=CC=C3)NC2=N1
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C(SC(F)(F)F)C([H])=C1[H]
[H]O[P@](=O)(C([H])([H])[H])[C@]([H])(C(=O)N([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]OC1=NC2=C(C([H])=C([H])C(Cl)=C2[H])C(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C#N
[H]N(C(=O)C1=NN(C2=C1C([H])([H])C1=C2C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C(C(N2C(=O)SC3=C(N=C(N=C23)C([H])([H])[H])N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C(N=C2C([H])=C([H])C(OC([H])([H])[H])=C([H])N12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C2N(C(=O)N(N3C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])S(=O)(=O)C4=C([H])C5=C([H])C([H])=C(Cl)C([H])=C5C([H])=C4[H])C([H])([H])C3([H])[H])C2([H])[H])C(=N1)C([H])([H])[H]
CCC1=C(F)C(OC)=NC(=N1)N1C[C@H]2C(=O)N(C)C(=N)N[C@]2(C1)C1=CC(F)=CC=C1F
[H]N(C1=NC([H])=NC2=C1N=NN2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(C1=NC2=C(N=C([H])N2C2=NN([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C2[H])C([H])=C1[H])[C@]([H])(C1=NC([H])=C(F)C([H])=N1)C([H])([H])[H]
[H]C1=C2N3C(=NC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C(=O)C2=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])\N=C(/[H])C1=C(N=C2SC(=C([H])N12)C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C(=C1[H])[N+]([O-])=O
[H]N([H])S(=O)(=O)C1=C(N([H])C([H])([H])C2=C([H])C(=O)OC3=C2C([H])=C([H])C(Cl)=C3[H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C([H])C(=C([H])C([H])=C2N=C1[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=NN([H])C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])SC([H])=C2[H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C1([H])O[C@@]([H])(C2=C(OC([H])([H])[H])C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(=O)[C@]([H])(N([H])C(=O)C1=C(Cl)C(=C(OC([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])[H])C1=NN(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C2C(O[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C(=C(C([H])=C1[H])N1C(=O)C2=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C3=C([H])C([H])=C([H])N=C3C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C2C1([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1Cl)C(=O)C([H])([H])N1C2=C(N=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H]
[H]OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])[C@@]([H])(O[H])C(=O)OC([H])([H])C1=C([H])[C@@]2([H])[C@@]3([H])O[C@@]4(O[C@@]3(C(=C([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]2(O4)[C@]2([H])C([H])=C(C(=O)[C@@]2(O[H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)N([H])\C(=C(\[H])C2=C(OC([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C([H])C([H])=C2[H])C1=O
[H]OC1=C2O[C@@]3([H])C4=C(C([H])=NC(=N4)N([H])[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]C1=NC2=C(OC(=N2)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C([H])([H])C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC1=C(Cl)C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C#CC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=NOC(=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1([H])C([H])([H])C(F)(F)C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N(C(=O)C1=C(C2=C([H])C(Cl)=C([H])C([H])=C2N1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=NC(SC2=C(Cl)C([H])=C([H])C([H])=C2[H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)[C@@]([H])(N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3F)C([H])=C2C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(=C(C([H])=C1[H])C1=NOC(=N1)C1=C([H])C(C#N)=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C(Cl)C(OC3=C([H])C(=C(O[H])C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C2N1[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])N(C2=C1C([H])=C([H])C([H])=N2)S(=O)(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])C1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C1=C2C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(SC2=C([H])C([H])=C(Cl)C([H])=C2[H])=NN(C1=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])N2C([H])=C([H])N=C2C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1[C@@]1([H])N(C(=O)[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CCCCCCCCN1C=C(CN(CCC)CCC)C2=CC(=CC=C12)C1=CC(C)=CC=C1
[H]N([H])C1=NC(C2=C([H])C([H])=C([H])O2)=C2N=C([H])N(C2=N1)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])F)C([H])=C2C(=N1)C([H])([H])C1=C([H])C(F)=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C(C([H])=C2C([H])=C3C(=NC2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(=O)[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C(=O)O[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])=C(N1C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C2C(=C([H])C(=C1[H])C([H])([H])[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=O)S2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=S)N([H])C1=NC2=C(C([H])=NC(=N2)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])C#CC1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(SC([H])([H])C2=NC(=C(S2)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(Cl)=C1[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C1=NC(=NO1)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])S1(=O)=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)[C@@]2([H])C([H])([H])C([H])([H])[C@@](C3=NN=C(S3)C([H])([H])[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC1=NN=C(N1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])S1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C(N=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C#N)C([H])([H])C1=C([H])C([H])=C([H])O1
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])C2=NC([H])=C(S2)C2=C([H])C([H])=C([H])O2)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N(\C(=C1/C(=O)N([H])C2=C([H])C(=C([H])C([H])=C12)C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N(C(=O)OC2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=NC(=C(N([H])C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])N(C([H])([H])[C@]1([H])C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C(=O)C1([H])C([H])([H])C1([H])[H]
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]C1=C([H])C([H])=C2\C(=N\S(=O)(=O)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])=C(C(=O)C2=C1[H])[C@]([H])(C(=O)OC([H])([H])[H])C(=O)C([H])([H])[H]
[H]N(C#N)C(=N/C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)OC([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])C1([H])[H])\N([H])C1=C([H])C([H])=C(C2=C([H])N=C([H])O2)C(OC([H])([H])[H])=C1[H]
[H]\C(=C(\N1N=C([H])N=C1[H])C(=O)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(OC2=C(F)C(=C(F)C(OC3=C([H])C([H])=C([H])C(N([H])C(=O)N([H])[H])=C3[H])=N2)C([H])([H])[H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@](C(=O)OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H]
[H]N(C1=C(Cl)C([H])=C(Cl)C(OC([H])([H])[H])=C1[H])C1=C2C([H])=C([H])C(C#CC3=NC(=C([H])C([H])=C3[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C2=NC([H])=C1C#N
CC1=C(C=C(C=C1)C(=O)N[C](=O)(NCC1=CC=C(C=C1)N1N=C(C=C1NC(=O)NC1=CC=CC2=CC=CC=C12)C(C)(C)C)C1CCCC1)C(O)=O
[H]N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C(C2=C(N=C([H])N=C12)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])N1C(=NC2=C([H])C(=C([H])C([H])=C12)N(C(=O)C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])[H])N([H])C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2O1)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CN(C)C(=O)OC1=CC=C(C=C1)C1=CN2C(C=CC=C2NC=O)=[N]1C
[H]ON(C(=O)N([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(SC2=C([H])C([H])=C([H])C([H])=C2N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=NN(C(=C2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC2=C([H])C([H])=C(OC3=NC(S[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=NC(Cl)=C3[H])C([H])=C2C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C([H])C([H])=C(C([H])=C12)C(C(=O)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N1C([H])=C(C2=C1N=C([H])C([H])=C2[H])[C@]1([H])C([H])([H])N(C(=O)C(OC2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C(C([H])=C3C([H])=C2C([H])([H])C([H])([H])C([H])([H])F)[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=NC2=NN(C(N([H])C([H])([H])C([H])([H])[H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]C1=NC([H])=C(O1)[C@@]1([H])C([H])([H])C2([H])N(C([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C(Cl)C([H])=C([H])C([H])=C3[H])[C@@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])C1([H])C([H])([H])C(=O)N(C(=O)C1([H])[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])[C@@]1([H])C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(OC([H])([H])[C@@]([H])(O1)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N1C(=O)C([H])([H])C2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=O
CC(C)(C)C(=O)NCC(=O)N1CCC[C@H]1B(O)O
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C(=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C2=C(N([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C3([H])[H])C(=O)C([H])=C(N([H])C(=O)\C(=C(/[H])\C(\[H])=C([H])/[C@]([H])(OC([H])([H])[H])[C@@]([H])(OC(=O)N([H])[H])\C(=C([H])\[C@]1([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O
[H]OC(=O)[C@]([H])(N([H])C(=O)C1(N([H])C(=O)[C@@]([H])(S[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N=C(C([H])=C1[H])C1=C([H])SC([H])=C1[H]
[H]N([H])C1=N[C@](C(=O)N1C([H])([H])[H])(C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1F
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[H]N(C(=O)C1=C2N=C(OC2=C([H])C([H])=C1[H])N1C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])[H])C1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C(=O)[C@]([H])(N([H])C(=O)C1=C(Cl)C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])[H])C1=NN(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(S1)C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C(F)C([H])=C([H])C(=C1F)S(=O)(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)P(=O)(O[H])O[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N(C(=O)[C@@]([H])(N([H])C(=O)C2=C([H])C([H])=C(O2)C([H])([H])N([H])C1=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C3F)C([H])([H])C2([H])[H])C2=NN(C(=O)N12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N(C2=C1C([H])=NC(=N2)C#N)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=NOC3=C2C([H])([H])C2=C([H])C(O[H])=C([H])C([H])=C32)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C([H])=C1C1=C2C([H])=C(N([H])C2=NC([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=C1OC([H])([H])O2)C1=NN=C(O1)SC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C3([H])C([H])([H])C3(C3=C([H])C([H])=C(C([H])=C3[H])S(F)(F)(F)(F)F)C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
CN(C1=NC=CC=C1CNC1=C2N=C(NC2=NC=C1Br)C1=CC=C(F)C=C1)S(C)(=O)=O
[H]N(C(=O)C([H])([H])N(C1([H])C([H])([H])N(C2=C([H])C([H])=C([N+]#[C-])C([H])=C2C1([H])[H])C([H])([H])C1=C([H])N=C([H])N1C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=NC([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C2C(=C1[H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])[C@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)N2C([H])=NN=C2[H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)C([H])([H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N=C1[H])N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C2=C(OC3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])=NC([H])=C2S1
[H]C1=C(N=C(S1)C([H])([H])[H])C([H])([H])N(C1=NC([H])=NC2=C1C([H])=C(C([H])=C2[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])C1([H])[H]
[H]C1=NN(C([H])=C1C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C(=O)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
N#C[Cu-]#N
[H]N1C(=O)[C@](C(=O)C2=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C12)(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])N(C2=NC(OC3=C([H])C([H])=C([H])C(=C3[H])C(=N[H])N([H])[H])=C(F)C(=C2F)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C(N=C2C([H])=C1[H])C([H])([H])[H])C(=O)O[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=O)[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H]