COC1=CC(CN(CCN(C)C)C(=O)NC2=CC=C(C=C2)C2=CNN=C2)=CC=C1
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C(=C([H])C([H])=N1)C1=C(C2=NC([H])=C([H])C([H])=C2N1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])[C@@]1([H])SC([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(O2)C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C2=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])[C@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=NN(C1=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=NC2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])C([H])=C([H])[H]
[H]C1=NC(=C([H])N1C([H])([H])[H])C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H])[C@]1([H])C([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C3=C(N=C([H])N=C3O[H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]C1=NN(C([H])=C1C1=C([H])C([H])=C2N=C([H])C3=C(N(C(=O)C([H])=C3[H])C3=C([H])C(=C(F)C([H])=C3[H])C(F)(F)F)C2=C1[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(C2=C([H])C([H])=C(Br)C([H])=C2[H])=C(C([H])=N1)[C@]1([H])OC([H])([H])C(=O)N1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(O2)C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N1N=C(C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]3(C2=C([H])C2=C1N(C(=O)C([H])=C2C(F)(F)F)C([H])([H])[H])C([H])([H])[H]
[H]ON1C(=O)C([H])([H])N([C@@]([H])(C1=O)C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)[C@]([H])(S[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C(=O)N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C(C([H])=C1[H])C1=NC2=C(OC3=C([H])C([H])=C(Br)C([H])=C23)C(=O)N1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])[H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])SSC([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C(=O)N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C4=NC([H])=C([H])C([H])=C4C([H])([H])[H])C([H])([H])C3([H])[H])N=C([H])N=C2N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]([H])(N1N=C(C([H])=C(C1=O)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C2=C(S1)S[C@]([H])(C(=O)N2[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)N1C(=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]C1=C([H])C(N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C(=C([H])C([H])=C3SC([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C2([H])[H])=C(F)C([H])=C1C(=O)C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(=O)N1\C(=N\N([H])C([H])([H])C(=O)O[H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]OC([H])([H])C([H])([H])N(C([H])([H])C1=C([H])SC(=N1)C1=C([H])N(C2=C(Cl)C([H])=C([H])C([H])=C12)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N1N=C2C(=C1C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C21
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N1C(=O)C2=C([H])C(I)=C([H])C([H])=C2N([H])C(=O)[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])SC(N([H])[H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])=NC([H])=C2[H])C([H])=C1[H])C(=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C(=O)C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(=N[H])N([H])[H])C([H])=C2C1([H])[H]
[H]N1C(=O)C([H])([H])[C@]2(C1=O)C(=O)N(C(=O)C1=C2C([H])=C([H])C([H])=C1[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2S1
[H]N([H])C(=O)C1=C(O[C@@]([H])(C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C(S1)N1C([H])=NC2=C1C([H])=C([H])C(=C2[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
C(N1CCCCC1)C1=CC2=CC=C(OC3=NC4=NC=CC=C4S3)C=C2O1
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H])C([H])([H])[H])C([H])([H])C(\[H])=C(/[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])N=C1[H]
[H]N1C([H])=C(C2=C(C(=O)N([H])C2=O)C2=C3C([H])=C([H])C([H])=C([H])C3=NC(=N2)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2Cl
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1O[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1O[H])C([H])([H])C1=C(O[H])C([H])=C([H])C(O[H])=C1[H]
[H]SC1=C(C([H])=C([H])C([H])=N1)C(=O)N1C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C2=C([H])N=C([H])N2C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C1([H])[H]
[H]N(C1=NC(=C(S1)C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C(F)(F)F)C1=C(Cl)C([H])=C(C([H])=C1Cl)C(F)(F)F
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]N(C(=O)[C@]([H])(C1=NN(N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC([H])([H])[H])C1=C2C(=C([H])C([H])=C1[H])C1=NN([H])C(C3=C([H])SC([H])=C3[H])=C1C2([H])[H]
[H]N([C@]1([H])C(=O)N(C2=C([H])C3=C(C([H])=C2[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)S1
[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C2N=C([H])C([H])=C([H])C2=C1[H])[C@@](C1=C([H])N(N=N1)[C@]([H])(C(=O)C([H])([H])OC1=C(F)C(F)=C([H])C(F)=C1F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C([H])=C([H])C(=O)C(=O)C2=C1[H]
[H]N1C([H])=C2C3=C1C([H])=C([H])C([H])=C3C(=O)N([H])C2([H])[H]
[H]C1=C([H])C([N+]#N)=C([H])C2=C1N(C(=N2)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])[C@]([H])(C(=O)OC([H])([H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C([H])C(Br)=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(N1C([H])=C([H])C([H])=C(C(=O)N([H])C([H])([H])C#CC2=C([H])C([H])=C3N=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C3=C2[H])C1=O)C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]OS(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(SC2=NC3=C(S2)C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1N=C(C2=C1C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C1(N3C(=O)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C(F)(F)F
[H]C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(=C1[H])[C@]1([H])C([H])([H])C([H])=C([H])C([H])([H])[C@]1([H])C#N
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]N(C1=C(C([H])=NC2=C1C([H])=NN2C([H])([H])[C@]([H])(Cl)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]C1=NC(Cl)=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(=C1[H])N1N=C(N(C1=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])[C@@]([H])(OC1=C(C#N)C([H])=C(F)C(Cl)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N2C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC2=C(OC([H])([H])[H])C([H])=C([H])C(N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])=C2S1
[H]N1N=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C1C(=O)N(C2=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])N([H])C([H])=O)[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC(=NC(=N1)N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C2=C([H])SC([H])=C([H])N2[H])C([H])([H])SSC(C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])[C@]([H])(O[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C(Br)=C2C2=C1C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]ON([H])C(=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C(F)C(F)=C(F)C(F)=C1F
[H]OC(=O)[C@]([H])(C([H])([H])C1=C([H])C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C(Cl)C([H])=C1C1=C(C([H])=NN1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N1N=C(C2=C1C([H])([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(C#CC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C(Cl)C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2C([H])=C([H])C([H])=C([H])N2N=C1C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])C1([H])[H]
[H]N(C1=NC(=NC2=C([H])C([H])=C(Cl)C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])C(O[H])=C(C(=O)N([H])C(C(=O)OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(\[H])=C(/[H])C2=C([H])N=C([H])C(C#N)=C2N([H])C2=C(C3=C(N([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])OC1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=NC(=NN2C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N=C(N=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C2=C(N([H])C(=C2C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(OC(=N1)C1=C([H])C([H])=C([H])C([H])=C1Cl)N([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C(\[H])=C(\C1=C([H])C2=C(N([H])C([H])=C2C2=C([H])C(=C([H])C(=C2OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N([H])C([H])([H])[C@]1([H])N(C([H])([H])C2=C([H])C(F)=C([H])C(F)=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC([H])([H])[C@@]([H])(C#N)N([H])C(=O)[C@@]([H])(N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N([H])C1=C(C([H])=C([H])[N+]([O-])=C1C1=C(Cl)C([H])=C([H])C([H])=C1[H])C(=O)C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C2=C(N=C(O2)N2C([H])([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C(O[H])=C1[H]
[H]OC([H])([H])[C@@]([H])(N1C([H])=C([H])C([H])=C(C(=O)N([H])C([H])([H])C#CC2=C([H])C3=NC(N([H])C4([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C4([H])[H])=C([H])N=C3C([H])=C2[H])C1=O)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]C(=O)C1=C([H])C([H])=C2N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]N([H])C1=N[C@@](C2=C([H])C(F)=C([H])C(F)=C12)(C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=C([H])C(C#CC([H])([H])[H])=C1[H])C1=C([H])N(C(=O)C(=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(\[H])=C2/C(=O)N([H])C3=C(C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C2=C1N=C(N2[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC2=C1C([H])([H])[C@]([H])(C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N([H])[C@]1([H])C([H])([H])N(C2=C(C#N)C3=C(N2C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C(=O)N(C([H])=N3)C([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C(=N2)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1([H])C([H])([H])C([H])([H])N(C2=NC(=C3C([H])=C(N([H])C(=O)C([H])([H])OC4=C([H])C([H])=C(OC(F)(F)F)C([H])=C4[H])C([H])=C([H])C3=N2)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])[C@@]1([H])SC2=C(C([H])=C([H])C(Cl)=C2[H])[C@@]1([H])OC([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]OC(=O)C1=C(C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])O[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])[C@@]([H])(N(C([H])([H])[C@@]1([H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C(C([H])=C(O[H])C([H])=C2[H])C([H])([H])[H])C(SSC1(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C2C(=N1)N(C(=O)C(C(=O)OC([H])([H])[H])=C2C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(Br)C(C#N)=C([H])C([H])=C1N([H])C(=O)N([H])C1=C(Br)C([H])=C([H])C([H])=C1[H]
[H]OC1=C2C([H])=C([H])C([H])=C([H])C2=NC([H])=N1
[H]C1=C([H])C(=C([H])C(F)=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C2C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]N(C1=C2C([H])=NN(C2=NC(SC([H])([H])C([H])([H])C([H])([H])[H])=N1)C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N=C(N1C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])C4=C([H])C(OS(=O)(=O)N([H])[H])=C(C([H])=C4[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C(=O)[C@]([H])(SC1=NC2=C(C([H])=NN2C2=C([H])C([H])=C([H])C([H])=C2[H])C(S[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])=N1)C([H])([H])[H]
[H]N(C(=O)C1=C(Cl)C([H])=NC([H])=C1Cl)C([H])([H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C(C#N)=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(N(C(=C1C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C([H])=C(N([H])[C@@]([H])(C([H])([H])SC4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=C3[H])S(=O)(=O)C(F)(F)F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=O)N(C2=C([H])C([H])=C(Cl)C([H])=C12)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
NS(=O)(=O)C1=C(O)C(Cl)=CC(Cl)=C1
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C([H])([H])N2C3=C([H])C([H])=C([H])C([H])=C3N=C2C([H])([H])OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(S1)C([H])=C([H])N=C2N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C(=O)C([H])([H])OC([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(F)C([H])=C(C([H])=C1F)[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
Cl.COC1=CC2=NC(=NC(N)=C2C=C1OC)N(C)CCCCCCN(C)C(=O)C1=CC=CC=C1CNCCCCCCNCCSSCCNCCCCCCNCC1=CC=CC=C1C(=O)N(C)CCCCCCN(C)C1=NC(N)=C2C=C(OC)C(OC)=CC2=N1
[H]C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)C2=C(SC(=C2[H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])C([H])([H])[C@]([H])(O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])[C@]1([H])C([H])([H])[H]
[H]N([H])C1=C2N=C(N([H])C3=C(Cl)C([H])=C([H])C([H])=C3C([H])([H])[H])C3=C([H])N=C([H])N3C2=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(O[H])C(O[H])=C1[H]
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)C([H])([H])C3(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2=O)C([H])([H])C1([H])[H]
[H]O[C@@]12C([H])([H])C([H])([H])C(=O)C([H])([H])[C@]11C3=C(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]2([H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1(N([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C([H])N=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C1=C(F)C([H])=C(C([H])=C1[H])N1N=C(Cl)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(OC(=N2)N2C([H])([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])N=C1[H]
[H]C1=C(N(N=N1)C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C1=NC([H])=C(N=C1OC1=C([H])C2=C(C([H])=C([H])N2[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])=C(C2=C([H])C([H])=C(O2)C([H])=O)C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C3=C([H])C([H])=C(O[H])C([H])=C3[H])C([H])([H])SSC1([H])[H])C([H])([H])[H])C([H])([H])[C@]([H])(OC1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)N([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C([H])=C3C(=C([H])C2=C1[H])C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])[H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C3([H])[H]
[H]N(C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC2=C([H])C(O[H])=C([H])C([H])=C2C1=O)SC1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C([H])C(C(=O)C3=C(N4C5=C3C([H])=C([H])C([H])=C5OC([H])([H])[C@@]4([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])[H])=C2C([H])=C1[H]
[H]OC(=O)[C@@]([H])(O[H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])[C@]([H])(O[H])[C@]([H])(C([H])([H])C([H])([H])[H])[C@]4([H])C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(N1C2=C([H])C([H])=C([H])C([H])=C2N(C2=C([H])C([H])=C([H])C([H])=C2F)S1(=O)=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]OC(=O)[C@](C([H])([H])[H])(C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC2=C(Cl)C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(C(=NN1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])C(=O)O[H])C1=C([H])C([H])=C([H])S1)C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1Cl
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C(=O)N(C([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C1SC([H])([H])C(=O)N1C1=NC([H])=C(S1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C(N=C1C1=C([H])C(=C([H])N=C1[H])C([H])([H])[H])C(F)(F)F
[H]OC1=C([H])C([H])=C([H])C2=C1C1=C(OC([H])([H])[H])C([H])=C(O[H])C3=C1[C@@]1([H])[C@@]2([H])OC2=C([H])C([H])=C([H])C([H])=C2[C@@]1([H])C([H])([H])C3=O
[H]N(C([H])([H])C1=NC(=C(N1C([H])(C([H])([H])F)C([H])([H])F)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C2=NOC3=C2C([H])=C(C(OC([H])([H])[H])=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(C#N)=C2OC(=C([H])C2=C1[H])C1=C([H])C(F)=C(O[H])C([H])=C1[H]
[H]OC1(C([H])([H])[H])C([H])([H])C([H])([H])N(C2=NC(N([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C3N=C(N=C3N2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])N(N=C1[H])C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N([H])C1=C([H])N=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C2=C([H])C(=O)C([H])([H])C([H])([H])[C@]2(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]O[C@]([H])(C(=O)N1C([H])([H])C(=O)N2[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)C3=NC([H])=C([H])S3)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])N(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(C2=C(C([H])=C1[H])C(=NO2)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])[H]