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[H]C1=C(SC2=C1C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[N@@+](C([H])([H])[H])(C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
C[C@@H]1CN(CCN1C1=NC=C(OCC2=C(F)C=C(C=C2)S(C)(=O)=O)C=N1)C(=O)OC(C)(C)C
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[H]O\C(=C(\[H])C(=O)C(\[H])=C(/O[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H]
COC1=CC2=NC=NC(NC3=CC(=CC=C3)C#N)=C2C=C1OC
CCCN(CCN1CCN(CC1)C1=CC=C(I)C=C1)C1CCC2=CC=C(O)C=C2C1
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[H]N=C(N([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])=C1[H])C([H])([H])N1C(=NC2=C([H])C(=C([H])C([H])=C12)N(C(=O)C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=NC(=C1[H])N1C(=O)N(C(=O)C11C([H])([H])C([H])([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=N2)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OP(=O)(O[H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])[C@]1([H])C(=O)N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=S)N([H])C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C1([H])[H]
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[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H])C1=C([H])C(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1\C([H])=C1\N([H])C(=O)N([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C2=C([H])N=C(Cl)C([H])=C2C(SC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C([H])([H])[H]
CC1=C(Cl)C(C)=C2C(N)=C(SC2=N1)C(=O)NC1CCOCC1
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C2=NOC3=C2C([H])=C([H])C(OC([H])([H])[H])=C3[H])C2=C([H])C([H])=C(C([H])=C12)C(F)(F)F)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1(C(=O)C2([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)[C@]1([H])N2C(=O)[C@]([H])(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@@]2([H])S(=O)(=O)C1(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N1C(=O)C2=C([H])C(I)=C([H])C([H])=C2N(C(=O)[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
CC1=NN(C(=C1)C(=O)NC1=CC=C(C=C1)C1=C(C=CC=C1)S(N)(=O)=O)C1=CC(=CC=C1)B(O)O
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C2=C(C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])[H])C([H])([H])C2=NC3=C([H])C(=C([H])C([H])=C3N2[H])[N+]([O-])=O)C([H])([H])N(C1=O)C([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C(=C([H])C([H])=C12)N1C([H])=NN=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
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[H]N1C(=NC2=C1C(=O)N(C(=O)N2[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C1=C([H])C([H])=C2N([H])N=NC2=C1[H])C([H])([H])[C@]([H])(C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C(C(=O)N1C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
FC1=C(C=CC=C1)S(=O)(=O)N1C2=CC=CC=C2C=C1S(=O)(=O)N1CCC2(C[C@@H]2NS(=O)(=O)C(F)(F)F)CC1
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[H]OC(=O)C([H])([H])C([H])([H])[C@]1(C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])N(C(=O)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C([H])N=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])[H]
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[H]C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])N([H])C(=O)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN([H])C2=C([H])C([H])=C(C([H])=C12)C1=C([H])N(N=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC(=O)C1=C([H])C([H])=C([H])C(=N1)C(=O)N([H])OC([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N(C1=NC([H])=NN1C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=NC(=NN2C(=O)C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C(N([H])C(=O)C([H])=C2[H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C1=NC2=C(OC3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C23)C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(OC1=C([H])C([H])=C(Cl)C(=C1[H])C([H])([H])N1C2=C([H])C(OC(F)(F)F)=C([H])C([H])=C2C(C2=NOC3=C2C([H])=C([H])C(OC([H])([H])[H])=C3[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C([H])N=C1C(F)(F)F)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2O[C@@]([H])(C([H])([H])[H])C(F)(F)F)S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H][C@]12C[C@@H](C(C)(C)C)[C@]34[C@@H](O)C(=O)O[C@H]3O[C@@]3(C(=O)O1)[C@@]1(O)[C@H](C)C(=O)O[C@H]1[C@H](OCC1=CC=C(Cl)C=C1)C243
[H]OC1=C([H])C([H])=C([H])C(=C1[H])N1C([H])=C(N=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C2=C(S1)C(=C([H])S2)C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])[H]
[H]C1=NN(C2=NC(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=N2)C(=O)C(Br)=C1Br
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])OC([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1C([H])([H])N([H])[H]
[H]N(C(=O)OC1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\C(=[N+](/C([H])([H])[H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(C2=C1[C@]1(O[C@@]([H])(OC([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C(=N[C@@]([H])(C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]C1=C([H])C([H])=C(C(=N1)N1C([H])([H])C([H])([H])N(C(=O)OC2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C([H])=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)O[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])N2C(=O)N(N=C12)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1([H])C3=C([H])C([H])=C([H])C([H])([H])[C@@]3([H])[C@@]([H])(N(C(=O)C([H])([H])[H])[C@]1([H])C([H])([H])[H])C2([H])[H]
[H]N(C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])N(C([H])([H])[H])[C@@]([H])(N2[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C2=C(N(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C([H])=C(F)C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3C([H])=C(F)C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C1(C2=NN=C3N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N2N(C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@@](N([H])[H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H])C(=O)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC(C)CN1C=C(C=N1)C1=CC(NC2=CC=C(OC(F)(F)F)C=C2)=NC=N1
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(N([H])S(=O)(=O)C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])C([H])([H])[C@@]3([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[C@@]([H])(C([O-])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C([H])C([H])=C([H])S2)C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC(Cl)=NC2=C1N=C([H])N2C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])[C@]([H])(N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])[C@]1([H])C(=O)N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(N([H])C2=NC3=C(N=NN3[C@]34C([H])([H])[C@@]5([H])C([H])([H])[C@]([H])(C([H])([H])[C@](O[H])(C5([H])[H])C3([H])[H])C4([H])[H])C([H])=N2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=NC([H])=C([H])N2C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]OC1=C([H])C(F)=C([H])C([H])=C1C1=C([H])C(=C(C#N)C(=N1)N([H])C(=O)C1=C([H])C([H])=C([H])O1)C1=C([H])C(N([H])C(=O)C([H])([H])[C@@]([H])(N([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=NC(=C([H])N1C([H])([H])[H])C(=O)N(C([H])([H])C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])[C@]2([H])C([H])([H])N(C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@]12[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@]([H])(C([H])([H])C([H])([H])N2C(=C(C(C(=O)OC([H])([H])C([H])([H])[H])=C2C([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[N+]([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N2C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])=O)[C@]([H])(C(=O)O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])OC(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=[N+](C2=NC3=C([H])C(Cl)=C(Cl)C([H])=C3N=C2N1C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])\C(\[H])=C1\N(C2=C(C([H])=C([H])C([H])=C2[H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])SC2=NC(=NC3=C2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2O3)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=NC([H])=C(N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(=C(Cl)C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N(C(=O)C1=C2N([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]C1=C(SC([H])([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])N(N=N1)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C1=NC(=NC2=C1N([H])C([H])([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N1C(C([H])=C(C#N)C#N)=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C(=O)N(C([H])([H])[H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@@]([H])(OC2=NSN=C2OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C2/C(=O)C3=C([H])C([H])=C([H])C([H])=C3S2(=O)=O)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C2=C(N([H])C1=O)C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C2=C(C(=NN2C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N([H])[C@]([H])(C1=NN=C(O1)SC([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC1=C([H])C([H])=C(SC([H])([H])C2=C([H])C(\C([H])=C(/C#N)C(=O)N([H])[H])=C([H])C(OC([H])([H])C([H])([H])[H])=C2O[H])C([H])=C1[H]
[H]N([H])C([H])(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H][C@@]12O[C@]1(CO)[C@@]1([H])[C@H](O[C@]3([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C[C@@]1([H])[C@@H]2OC(=O)[C@H]1[C@@H]([C@H]([C@@H]1C1=CC=C(O)C=C1)C1=CC=C(O)C=C1)C(=O)O[C@@H]1[C@]2([H])O[C@]2(CO)[C@@]2([H])[C@H](O[C@]3([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C[C@@]12[H]
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[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=C([H])S2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
COC1=C(C=CC=C1)C1=CN2C(=N1)N=C(C)C(CN)=C2C1=CC=CC(Cl)=C1
[H]OC(=O)C1=C([H])C([H])=C([H])C(N([H])C(=O)C2=C(N([H])C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])=C1[H]
C\C(NNC(=S)N1CCCC2=C1C=CC(=C2)C(O)=O)=C1/C(C)=NN(C1=O)C1=CC=C(C)C(C)=C1
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[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)N(C3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(=O)OC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12
[H]N(C(=O)C1=C([H])C(=NN1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NN2C(N=C([H])C([H])=C2[C@@]2([H])C([H])([H])[C@@]3([H])N(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C1C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)C(=S)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N(C(=O)C3=C([H])C([H])=C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2=C1[H]
[H]C1=C(OC(=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])SC([H])([H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C(O1)C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C2OC3=C(OC(=O)C2=C1OC([H])([H])[H])C([H])=C(C([H])=C3OC([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C(=C([H])C([H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=N2)=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OP(=O)(O[H])O[H])C([H])=C1[H])C1=NC(=NO1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C(OC([H])([H])[H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])(N3C(=O)OC([H])([H])C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])\N=C(/N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C([H])C(=C([H])C([H])=C3[H])C(F)(F)F)C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(SC([H])([H])C([H])([H])[H])=NC2=C(S[C@]([H])(C([H])([H])[H])C2([H])[H])C1=O
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C(N=C([H])C(=O)N1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C(N=C(O1)C1=C2C([H])=C([H])C(=NC2=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C1=C(C([H])=C(O[C@@]3([H])C([H])([H])[N@]4C([H])([H])C([H])([H])[C@]3([H])C([H])([H])C4([H])[H])C([H])=C1[H])C2([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1=C(N([H])C2=C(Cl)C(=C([H])C([H])=C2Cl)C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])N=C1N([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(N2N=C3C(=C2C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C3=O)C([H])([H])C(F)(F)C([H])([H])[H])C(Cl)=C1[H]
[H]N1C(=NC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=NC(OC([H])([H])C([H])([H])[H])=C1C#N)N([H])C(=O)C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C3C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(N([H])C(=O)C2=C([H])C(N([H])C(=N[H])N([H])[H])=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])C([H])([H])C(=O)O[H]
[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C(=C(C([H])=C1[H])C1=NOC(=N1)C1=C([H])C(C#N)=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C(F)C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N3C(=O)C([H])([H])C4(C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3=O)C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]OC1=C([H])C([H])=C2C(OC(=O)C3=C2C(C([H])=C([H])[H])=C([H])C(OC([H])([H])[H])=C3[H])=C1C([H])([H])[H]
[H]N(C1=NC(C2=C([H])N=C(N2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C(F)C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(OC([H])([H])[H])C(=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C(F)(F)F
[H]N([H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C(=O)N([H])C1([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C(=N1)N([H])[H])C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])OC(=N1)C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(N=C([H])N=C2SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C(Br)C(=O)C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3([H])[C@]2([H])C1([H])[H]
[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N1C([H])=C([H])C(=C(N([H])S(=O)(=O)C([H])([H])[H])C1=O)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=NC(=NC(=C1N(C([H])([H])C1=C([H])N(C(=O)N([H])C1=O)[C@]1([H])O[C@]([H])(C([H])([H])OP([O-])([O-])=O)[C@]([H])(O[H])C1([H])[H])C([H])([H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@@]([H])(C([O-])=O)C([H])([H])C([H])([H])C([O-])=O)C([H])([H])[H])C([H])([H])[H])N([H])[H]
[H]N1C(=O)C([H])=C([H])C2=C1C([H])([H])[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@]22N(C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])[C@]5([H])[C@@]6([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]45C4=C(N([H])C(=O)C([H])=C4[H])C6([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N=C1[H])C([H])=C([H])C1=C(C([H])=C(C([H])=C1[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C2=O
[H]N(C(=O)C(N([H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C(C#N)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C(=O)N([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(\N=C1/C(=O)N([H])N=C1C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
OCCOCCOC1=NC(C(=O)NCC2CCC2)=C(NC(=O)C2=C3C=CC=CC3=NC=C2)C=C1
[H]C1=C([H])N2C(=NN=C2C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(OC2=C(C(Cl)=C([H])C([H])=C2[H])C([H])([H])[H])=C1[H]
NC(=O)CC1=CC(=CC=C1)N1N=C(C=C1NC(=O)NC1=C(Cl)C(Cl)=CC=C1)C1CCCC1
[H]OC(=O)C1=C(Cl)N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NC2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
OB(O)CNS(=O)(=O)C1=CC2=C(S1)C(Cl)=CC=C2Cl
[H]OC1=C([H])C(F)=C([H])C([H])=C1C1=C([H])C(=C(C#N)C(=N1)N([H])C(=O)C1=C([H])C([H])=C([H])O1)C1=C([H])C(N([H])C(=O)C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])C([H])([H])C1=C(N=C(N=C1[H])N([H])[H])N([H])[H]
[H]N1C2=C(C([H])=C([H])C3=C([H])N=C(C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C2=C1C([H])([H])N([H])C2=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C(C2=C([H])OC3=C([H])C([H])=C(F)C([H])=C23)=C(C1=O)C1=C([H])N(C2=C([H])C([H])=C(Cl)C([H])=C12)C([H])([H])[H]
[H]N(C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C2C([H])=C(Cl)C(Cl)=C([H])C2=N1)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=NC2=C(O[H])C([H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N1C(=S)S\C(=C(\[H])/C(/[H])=C(\[H])C2=C([H])C([H])=C([H])O2)C1=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])[H])C([H])([H])SC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(N1C(SC([H])([H])SC2=NN=C(N2N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C(SC3=C2C([H])([H])C([H])([H])C([H])([H])C3([H])[H])N([H])C(=O)C([H])([H])Cl)=NN=C1C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])Cl)C(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]O[C@]([H])(C(=O)N([H])N([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)[C@]([H])(N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C4=C(C(C(=O)C5=C([H])C(Cl)=C(Cl)C([H])=C5[H])=C(S4)N([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C2=C([H])C([H])=C3C(=C2O1)C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C3([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC(F)(F)F)S(=O)(=O)N1N=C(C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1([H])N(C(=O)C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C2=C1N([H])C1=C2C([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C(=O)N([H])C1=C([H])C([H])=C2C(=NC([H])=NC2=C1[H])N([H])C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]C1=C([H])C2=NC([H])=C([H])C([H])=C2N1S(=O)(=O)C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])N=C4N3C([H])=C(Cl)C([H])=C4Cl)C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C2C([H])=NN(C2=NC([H])=C1C(=O)O[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C(OC1=O)C1=C([H])C([H])=C(C2=NC3=C(N2[H])C(=O)N(N=C3C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N=C(N([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])OC(=O)[C@]([H])(N([H])C(=O)C2=C([H])C(=C([H])C([H])=C2[H])C(=N[H])N([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])C2=C([H])C([H])=NC([H])=N2)C([H])=C1[H])C1=NC(=C([H])S1)C1=C(F)C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N2C(=O)N(C([H])([H])C3=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])[C@]2([H])C1([H])[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1F
[H]N(C1=NC([H])=NN2C([H])=C(C3=NN=C(O3)C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(=C12)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(F)C([H])=C(F)C(=C1[H])C(=O)N([H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])[C@@]1([H])C(=O)N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])N(C(=O)C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])[H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1[H])C1=NOC(=N1)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1(C#C[H])C([H])([H])C([H])([H])[C@]2([H])[C@]3([H])C([H])([H])C([H])([H])[C@@]4([H])C([H])([H])C5=C(N=C(O5)S(=O)(=O)C([H])([H])[H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]OC(=O)C1=C(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2N1C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C(OC2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(OC([H])([H])C([H])([H])OC2=NC([H])=C([H])C(=N2)C([H])([H])[H])=NC([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(N1C2=C([H])C([H])=C(Cl)C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@](C([H])([H])N([H])C1=C2C([H])=NN(C2=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]C1=NN(C2=C1C([H])([H])N(C(=O)C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])C2([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(S[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C(Cl)N([H])C4=C3C(=C([H])C([H])=C4[H])[C@]2([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(\N=C(/[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]O\N=C1/C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C1=C(N([H])C(=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C1=C2C(=NC([H])=N1)N=C(C([H])=C2C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2O1)C(=O)N([H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(Cl)SC(=C1[H])S(=O)(=O)N1N=C(C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(C(=O)C2=C([H])N(C3=C2C([H])=C([H])C(=C3[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])S([O-])(=O)=O)=C2N1[C@]([H])(SC2([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
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[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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[H]N=C(N([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C(=C2[H])C(=O)OC([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
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[H]OC(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]OC1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C(O[H])=C([H])C(=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(O[H])C(N([H])S(=O)(=O)C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C(=O)O[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])[C@]([H])(N1C([H])=NC([H])=C1[H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C2=C([H])C([H])=C(Cl)C(C#N)=C2C(SC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C([H])([H])[H]
[H]C1=C2C3=C(N=C(N=C3N1C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])N(C1=C(C([H])=C(C#N)C([H])=C1[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])SC2=C([H])C(O[H])=C([H])C([H])=C2S[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C(Cl)=C1[H])N(C(=O)C([H])([H])[H])C2([H])[H]
[H]N([H])C([H])([H])C1=C([H])C(N([H])C(=O)C([H])([H])N2C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N(\N=C(/[H])C1=C([H])[N+](=C([H])C([H])=C1[H])C([H])([H])[H])C(=O)C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
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[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C([H])C(F)=C(C([H])=C2[H])C2=C([H])N3C([H])=C([H])C(=C([H])C3=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C(OC(F)(F)F)C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C(=O)N(C1=C(OC([H])([H])[H])C(=C(Cl)C([H])=C1[H])C([H])([H])OC1=C2N=C(C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C(C(=O)C([H])([H])[H])C2=C(C([H])=C([H])C(=O)O2)C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])=C4C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
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[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])OC([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]OC1=C2N=C(N([H])[H])N(C2=NC(=N1)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(SC([H])([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2Cl)=NC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12
[H]N(C(=O)C([H])([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(C([H])=C1[H])C([H])([H])[H]
FC1=CC=CC(=C1)C(=O)NC1=CC=CC(OC2=NN3C=C(NC(=O)C4CC4)N=C3C=C2)=C1
[H]N(C1=C([H])C(Br)=C([H])C([H])=C1[H])C1=NC([H])=NC2=C1SC1=C2C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2S1)C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)N1C(=O)N([H])C(=C(C(=O)OC([H])([H])[H])[C@@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[N+]([O-])=O)C([H])([H])[C@]1([H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
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[H]OC(=O)C1=C([H])C([H])=C(O1)C1=C([H])C2=C(N=C([H])N=C2N([H])C([H])([H])C2=C([H])C([H])=C(O2)C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
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[H]N1C(=O)[C@]2(N(C(=O)[C@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1F)N(C([H])([H])C#C[H])C([H])([H])C1=C(C([H])=C2N=C(N=C(O[H])C2=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])[H])C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2C([H])([H])[H])=N1
[H]C1=C(SC2=C1C([H])=C([H])C(Cl)=C2[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC([H])([H])C([H])([H])N2C([H])([H])[H])[C@@]([H])(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])C1=NN(N=N1)C([H])([H])[H])C2=O
[H]C1=C(N(C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(Cl)=C([H])OC3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C1([H])[H]
[H]N1C([H])=C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])(OC4=C([H])C(Cl)=C(Cl)C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]N(C1=NC(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N1C(=C(C2=C([H])C([H])=C([H])C(Cl)=C12)[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@@]1([H])F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])S[C@]1(C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(=N2)C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NN=C(SC([H])([H])C2=NOC(=C2[H])C([H])([H])[H])N1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])[C@]1([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])N=C2N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])OC2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@](O[H])(C1=C(SC([H])([H])[H])N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C1(C(=O)N([H])N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C1=C(C(=O)OC([H])([H])[H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N=C(OC([H])([H])[H])N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C(C([H])=C([H])C([H])=C12)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C2=C(C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1N=C([H])C2=C1N=C(N1N=C(N=C21)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@](C1=NC([H])=C([H])N1C([H])([H])[H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C2N(C(=O)C([H])=C(C3=C([H])C([H])=C([H])C(Cl)=C3[H])C2=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])[C@]([H])(OC([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=C([H])C(=C(C#N)C([H])=C1[H])C1=C(Cl)C(Cl)=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C2C([H])=C([H])C(=C([H])C2=NC([H])=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(O[H])C([H])=C1C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C(=N1)C([H])([H])[H])C([H])([H])[H]
COC1=CC=C2N(C=C(CC(=O)NS(=O)(=O)C3=CC=CC=C3C)C2=C1)C(=O)C1=CC=C(Cl)C=C1
OC(=O)CCCCCC1=CC2=NC(=NN2C=C1)C1=CC=C(C2=CC=CC=C2)C(=C1)C(F)(F)F
[H]OC1=NC([H])=C([H])N1[C@]([H])(C([H])([H])[H])[C@@]([H])(C1=C([H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]