[H]N(C(=O)OC([H])([H])[C@@]1([H])C(=O)N2[C@]1([H])S(=O)(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(OC2=NC(OC3=C([H])C([H])=C4OC([H])([H])OC4=C3[H])=NC([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)C([H])([H])F)C([H])([H])C(=O)O[H]
[H]\C(=C(/C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(S1)C(=NC1=C(N=NN21)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C2=C([H])C([H])=C([H])C(\C([H])=C(/[H])C3=NC4=C(C([H])=C([H])C(Cl)=C4[H])C([H])=C3[H])=C2C([H])=C1[H]
[H]ON([H])C(=O)[C@@](C([H])([H])[H])(C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])=C([H])C([H])=C(C1=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NN=NN1C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(\C([H])=C(/[H])C([H])([H])N([H])C2=C([H])C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C3([H])[H])C(=C2[H])C(F)(F)F)=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C2=NC(=O)C([H])([H])S2)[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H]
[H]N=C(N(C([H])([H])[H])C([H])([H])[H])C1=C([H])SC(=C1[H])C(=O)N([H])C1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]OC(=O)C([H])([H])C1(C([H])([H])S[C@@]([H])(C2=C([H])C(\C([H])=C(/[H])C3=NC(=C(S3)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C(Cl)=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N1N=C(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(SN=C2C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N=C1C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
CC(C)[C@H](CO)NC1=NC(NC2=NC3=CN=CN=C3N2C(C)C)=CN=C1
[H]N([H])C1=N[C@@](C(=O)N1C([H])([H])[H])(C1=C([H])SC(=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=C([H])N=C1[H]
[H]O[C@@](C1=C([H])C(Cl)=C([H])C([H])=C1[H])(C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])[H])[C@@]1([H])C([H])([H])N(C(=O)N([H])[C@]([H])(C([H])([H])N([H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(OC([H])([H])[C@@]([H])(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C2([H])[H])=C1O[H]
[H]OC1=C(C([H])=C(Br)C([H])=C1[H])C1=NC2=C([H])C(=C([H])C([H])=C2N1[H])C(=N[H])N([H])[H]
[H]N([H])C1=NC2=C(C(=O)C3=C([H])C([H])=C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C([H])=C23)C(=N1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C1C([H])=C([H])C(Cl)=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])N=C(OC([H])([H])[H])C(Cl)=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C([H])([H])OC3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])C([H])([H])C(\Cl)=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H])C([H])=C1C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C4C(ON=C4C([H])([H])[H])=C3C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[C-]#N
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=NN([H])C(=C2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])C2=O)C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=C([H])C(=NN2[H])C2=C([H])C([H])=C([H])C(Br)=C2[H])C([H])=C1[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(C([H])([H])C([H])=C([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])C([H])([H])N1C2=C([H])C([H])=C(C([H])=C2C2=C1C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2N([H])C(=NC2=NC(=N1)N([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]OC1=C([H])C([H])=C(C(N([H])C2=C([H])C(Cl)=NC(=N2)N2C([H])=NC3=C2C([H])=C([H])C([H])=C3[H])=C1[H])C([H])([H])[H]
[H]C1=C([H])N(C(=N1)C([H])([H])N1C([H])([H])C([H])([H])C2(C(=O)N(C3=C([H])C([H])=C(C([H])=C23)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(=N1)N([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])OC1=C(C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(O1)C([H])([H])[H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C1=C(C([H])=C([H])N(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1=O)C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])C(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C(C(=O)OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=C1[H])C1=NN=C(N1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])[C@@]1([H])C([H])([H])O[C@]([H])(C([H])([H])[C@]1([H])O[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(I)=C(N([H])C(=O)C([H])([H])N([H])C([H])([H])[H])C([H])=C1[H]
[H]OP(=O)(O[H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]1([H])C(=O)N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=C([H])N=C1C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C(Cl)C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
C[C@H](O)C(=O)N1CCC(CC1)N1C(=O)N(C)C2=C1C1=NC(=CC=C1N=C2)C1=C2C=NNC2=CC=C1
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])N([H])C([H])([H])C([H])([H])C2=C([H])C(Br)=C([H])S2)[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=NC(=O)C([H])([H])S1
[H]N([H])S(=O)(=O)C1=C(F)C([H])=C(C([H])=C1[H])C1=C(N=C(O1)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C2N=C([H])C([H])=C(N([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])C2=C1[H]
[H]N([H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(O1)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C(N(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])=C(C#N)C#N
[H]N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]2([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])SSC2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N([H])[H]
[H]N1C([H])=C(C2=C([H])C(=C([H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CC1=CC(Cl)=C(OCCOC2=CC=C(CC(CN)C3=CC=C(C=C3)C3=C(Cl)C=CC=C3)C=C2)C(Cl)=C1
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)C1=NN=C(O1)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C([H])C(C3=NN=C(O3)SC([H])([H])C#CC([H])([H])OC(=O)C3([H])C([H])([H])C3([H])[H])=C2C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])C2=NC([H])=C(N=C12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=NN=C2C([H])=C([H])C(=NN12)C1=C([H])N(N=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
[H]N([H])C(=O)[C@]1([H])[C@]([H])(N([H])C2=NC(=NC([H])=C2Cl)N([H])C2=C([H])N(N=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])[C@@]2([H])C([H])=C([H])[C@]1([H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@]1([H])C([H])([H])O[C@@]([H])(O[C@]1([H])C1=C(O[H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H])\C2=C([H])N=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=NC(=NC(=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C#N
[H]\C(=C1/C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=C(C#N)C3=C(N2C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])C1=C(N=C2C([H])=C([H])C(Cl)=C([H])N12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(Cl)N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(F)C([H])=C2C(=O)C3=C(N([H])C2=C1[H])C([H])=C([H])C([H])=C3[H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(N([H])C2=NC(=C([H])S2)C2=C([H])C([H])=C([H])N=C2[H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])N1C([H])=NC(=C1[H])C([H])([H])[H])C(F)(F)F
[H]N([H])C([H])([H])C1=C([H])N=C(S1)[C@@]12C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N(C(=O)N([H])C1=C([H])C([H])=C(F)C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]OC(=O)C(\[H])=C(\C(\[H])=C(/[H])\C(\[H])=C(/C1=C([H])C(=C([H])C(=C1OC([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)C(F)(F)F)C([H])([H])[H])/C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)[C@@]([H])(N([H])C(=O)C1=C([H])C(N([H])C([H])([H])C([H])([H])[H])=C2C(=C1[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C(C([H])=C([H])C1=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])[H])N=C1[H]
[H]N1C(=O)S\C(=C(/[H])C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C1=O
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(O[H])C(N([H])S(=O)(=O)C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C2=C(C([H])=NC3=C(C([H])=C([H])C([H])=C23)C(=O)C([H])([H])[H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3OC([H])([H])C([H])([H])OC3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C2=C1C(=O)N([H])C2([H])[H]
[H]N([H])C([H])([H])C(=O)N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])[P@](=O)(OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NC(=NC([H])=C1C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C(=O)N1C([H])([H])C([H])(OC2=C(N=C([H])C([H])=N2)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1([H])[H]
[H]OC1=C([H])C(C(=O)C([H])([H])[H])=C(C([H])=C1O[H])C([H])([H])[C@]([H])(C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C(C([H])=C(O[H])C(O[H])=C1[H])C(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(F)=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])N2C([H])=C([H])C([H])=C2C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N1N=C2N(C([H])=NC3=C2C2=C(S3)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=S
[H]N(\N=C1\C2=C(N([H])C(Cl)=C2Cl)C(=O)N([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])O\N=C(/C([H])([H])N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@]1([H])N(C2=C([H])C(=NC(=N2)N2C([H])=NC([H])=C2[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]O[C@@]([H])(C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C(C(=O)N([H])C2=C(F)C([H])=C(C([H])=C2F)C2=C([H])C([H])=C([H])C(OC(F)(F)F)=C2[H])C([H])([H])SC1([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])SC([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C(C(=O)C([H])([H])[H])C(=NC(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])S(=O)(=O)N(C1=C([H])C(=C([H])C([H])=C1Cl)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@]1([H])C([H])([H])O[C@]([H])(O[C@@]1([H])C1=C([H])N=C([H])C([H])=C1[H])C(SC1=C(C#N)C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(OC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])N=C(S1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C2=C(N=C(N=C2O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])C2=C([H])C([H])=C(Cl)N=C2[H])C([H])([H])C1([H])[H])C1=C([H])N=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2F)C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C2=C(N([H])C(=N2)C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2F)C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1OC1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]\C(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC([H])=C1[H])=C1\C([H])([H])N2C([H])([H])[C@]3([H])C([H])([H])C([H])([H])[C@@]2([H])[C@@]([H])(C(=O)OC([H])([H])[H])[C@@]1([H])C([H])([H])C3([H])[H]
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[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)C(C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C2SN(C(=O)C2=C([H])C(=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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COC1=CC(=CC=C1)C1=CC=C2OC(=O)N(CC(=O)N(C)C3=CC=CC=C3)C2=C1
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O[C@H](COC1=CC=C(F)C=C1)CN1CCN(CC2=CC=C(Cl)C=C2)CC1
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[H]C([H])=C([H])C([H])([H])SC1=NC2=C([H])C([H])=C(C([H])=C2C(=O)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=O)C(=C(C(=O)OC([H])([H])C([H])([H])[H])C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C2N=C(C([H])=C(N2N=C1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C(F)(F)F)C(F)(F)F
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[H]N([H])C(=S)N1N=C(C2=C([H])C([H])=C(Br)C(Br)=C2[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N1C(=NC2=C1C([H])=C([H])C(=C2[H])C(=O)N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C(N=C3[H])C3=C([H])N(N=C3[H])C([H])([H])[H])C(=O)C2([H])[H])C([H])([H])C1([H])[H])C1=NN(C([H])=C1[H])C([H])([H])[H]
[H]C1=NC(=C([H])N1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]N(C(=O)C(\Cl)=C(/Cl)[S@@](=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@](N([H])C(=O)O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1(N2C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])C(=O)C([H])([H])OC([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]\C(=C1/C(=O)/C(=C(\[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]C1=C([H])C(=C(C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=O)OC(C2=O)(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C2=C(N([H])C(=O)\C2=C(\[H])C2=C([H])N(C3=C2C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC(=C(S1)C1=C([H])SC(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=NOC(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N([H])[C@@]2([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]2(C([H])([H])S(=O)(=O)N2C([H])([H])C([H])([H])C4(C5=C(C([H])=C([H])C([H])=C5[H])C([H])([H])C4([H])[H])C([H])([H])C2([H])[H])C3(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C1=NC3=C([H])C([H])=C(F)C([H])=C3C(C([O-])=O)=C1C([H])([H])O2
[H]OC(=O)C([H])([H])[C@@]1(O[H])C2=C(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])=C(F)C([H])=C2[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(N([H])C2=C1C(=O)C([H])([H])C([H])([H])C2([H])[H])C(\[H])=C1/C(=O)N([H])C2=C([H])C([H])=C(C([H])=C12)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
COC1=CC=C(\C=C\C2=C(/C=C/C(=O)NC(C)C)C(OC)=CC(OC)=C2)C=C1
[H]C1=C([H])C(=C([H])C([H])=C1O[C@@]1([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1([H])[H])C(=O)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])N(C(=N2)C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=S)N([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N2C([H])=C([H])N=C2C(=N1)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)C1=NN=C(O1)SC([H])([H])C(=O)C1=C(N(C(=C1[H])C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])[H]
[H]N1C2=C(C([H])=C1[C@@]1([H])C([H])([H])[C@]3([H])O[C@@]([H])(C([H])([H])C3([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H])C([H])=C([H])C([H])=C2[H]
[H]N([H])C1=C2C(SC(=C2C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])[H])=NC([H])=N1
[H]N([H])[C@]1([H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C(=N1)C([H])([H])[H])C([H])([H])C#CC([H])([H])OC1=NOC([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C#CC([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C(N([H])C2=C(F)C(Cl)=C([H])C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2N=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)[C@]1([H])N(C2=C([H])C([H])=C(C(N([H])C(=O)C([H])([H])O[C@]3([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C2[H])[N+]([O-])=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CN1C=C(C=N1)C1=CC2=C(C=CC3=C(C=C(CS(=O)(=O)NCCC4=NC=CC=C4)C=C3)C2=O)N=C1
[H]N([H])C(=O)C1=C([H])C([H])=C2C(=C1[H])N(C([H])=C2[C@@]([H])(C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(S1)C#CC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N([H])C1=NOC2=C([H])C([H])=C(C([H])=C12)N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])=C([H])N=C1C([H])([H])[H])C(F)(F)F
[H]OC([H])([H])C([H])([H])N(C(=O)C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C([H])=C2N1[H])[C@@]1([H])C([H])([H])SC([H])([H])C1([H])[H]
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[H]N1C(=O)C([H])([H])C11C([H])([H])C([H])([H])N(C(=O)OC2(C([H])([H])C2([H])[H])[C@]2([H])N([C@]([H])(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])OC2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]1([H])C([H])([H])N(C2=C(Cl)C([H])=C([H])C([H])=C2\C([H])=C2/SC(=O)N([H])C2=O)C([H])([H])C1([H])[H]
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[H]N(C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1=C([H])C(Cl)=C([H])C([H])=C1[H]
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[H]N(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1F)C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
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[H]OC1=C(C([H])=C2C(=NC([H])=NC2=C1C([H])([H])C([H])=C([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H])[N+]([O-])=O
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[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])P(=O)(OC1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H])OC1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])=C([H])C2=NC([H])=NC(N([H])C3=C([H])C([H])=C(OC4=C([H])C([H])=C([H])C5=C4N([H])C(=O)C5([H])[H])C(Cl)=C3[H])=C12
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[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(O2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C2=NC(=C([H])S2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N([C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])S(=O)(=O)C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N(C1=NC(=NC(=O)N1[H])C1=C([H])N([H])C2=NC([H])=C([H])C([H])=C12)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C2([H])[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(\C([H])=C(/[H])C2=C([H])C([H])=NC([H])=C2[H])=C([H])N=C1[H])C([H])([H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]C1=C([H])C(=O)N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=NC(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@@]1([H])OC([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N1C([H])([H])C([H])([H])[C@@]([H])(F)[C@@]([H])(OC2=C([H])C([H])=C([H])C3=C2N=C(C([H])=C3[H])C2=NN=C3C([H])=C([H])C([H])=C([H])N23)C([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])S(=O)(=O)C1=C([H])C(OC2=C([H])C([H])=C([H])C(=C2[H])C2=C(N=C3N2C([H])=C([H])C([H])=C3Cl)C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1=NOC(=N1)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N(C1=C(N=C2C([H])=NC([H])=C([H])N12)C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C3=C([H])C(F)=C([H])C([H])=C3F)C([H])=C2[H])C([H])=C1N([H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N(N=C(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C1([H])[H])C(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C1=C(C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C([H])=C1[H])C(=O)C2=O
[H]N([H])C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])[C@]1([H])C([H])([H])C2([H])N(C(=O)C3=C(C(Br)=C(OC([H])([H])C([H])([H])C([H])([H])[H])S3)C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)N([H])C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C1=C([H])C(=NO1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=NC([H])=C2C([H])([H])C(=O)C2=C([H])C([H])=C([H])C(=N2)C2=C(F)C(=C([H])C([H])=C2F)C([H])([H])C([H])([H])[H])C1([H])[H]
[H]O[C@](C1=C([H])C2=C([H])C(=C(C([H])=C2N1[H])C(F)(F)F)[N+]([O-])=O)(C([H])([H])[H])C([H])([H])OC(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C(C([H])=C3C([H])([H])[H])C3=NC(=NS3)C(F)(F)F)C([H])=C2C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])S(=O)(=O)[C@]1([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@@]([H])(O[C@]2([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]2([H])OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]1([H])OC(=O)C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C2=C([H])C(=C([H])C(=C2N([H])C1=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])=C(C(=O)N2C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C(=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C(S1)C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=NN=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C1=NC([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C2=C1C(OC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])[H]
[H]N1C(=O)C([H])([H])OC2=C1C([H])=C(C([H])=C2[H])C1=C(C([H])=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(F)(F)F
[H]OC([H])([H])C1(C([H])([H])N([H])C(=O)C2=C3C([H])=C([H])C([H])=C([H])N3C(=N2)C([H])([H])N2C([H])([H])C([H])([H])C(F)(F)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F
[H]N1C(=O)N=C(C([H])=C1N(C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1C1=C(C(=NO1)C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])SC1=NC(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C(OC2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC2=NC([H])=C(Br)C([H])=N2)=N1
[H]OC(=O)C([H])([H])C1=C2N(C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])[C@]([H])(N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C2([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C12)C1=C(F)C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C1N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[C@]1([H])[C@]3([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C3([H])[H])C([H])([H])[C@]21[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]1([H])OC2=C(C(OC([H])([H])C([H])([H])C([H])([H])OC3=C(C(OC([H])([H])[H])=C(C([H])=C3[H])C3=C([H])SC([H])=N3)C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])OC1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1N([H])S(=O)(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C2C([H])=C([H])N(C2=N1)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
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[H]C1=C(F)C([H])=C(C(=C1[H])[C@@]1([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])[H])C(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C([H])S2)C([H])([H])C2=C([H])C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2C1([H])[H]
[H]C1=C(C2=C([H])C([H])=C(C([H])=C2N1C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(N2C(=NC3=C2C([H])=C([H])N=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(C1=NC2=C(C([H])=N1)C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C21)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C2=C1C([H])([H])N(C(=O)C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C(F)(F)F)S(=O)(=O)C([H])([H])[H])C2([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N(C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C1(N2C([H])([H])C([H])([H])N(C(=O)[C@@]3([H])C([H])([H])N(C([H])([H])[C@]3([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1N=NN=C1C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]2([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C(F)=C([H])C(F)=C1[H])C([H])([H])[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=NN=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=NC(=NC([H])=C3C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(OC1=C(C2=C(C([H])=C1C([H])([H])C([H])([H])C([H])([H])[H])C(=NO2)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=C(N=C2C([H])=C(C(=C([H])C2=N1)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C2C(=NN1C([H])([H])[H])N1C(=N[C@@]([H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])N(C2=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C1=NN(C(=O)[C@]2([H])C([H])([H])C([H])=C([H])C([H])([H])[C@]12[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])OC1=O
[H]C1=C2C3=C(N=C(C([H])=C3N(C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])N1C1=C(Cl)C([H])=C(C#N)C([H])=C1[H]
[H]C1=C(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C(=NC3=C2C([H])=C([H])N=C3[H])C([H])([H])[H])C2=C([H])C(=C([H])C([H])=C2N1C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(N([H])C(=O)C2=C(C([H])=C([H])S2)S(=O)(=O)N([H])C2=C(Br)C(=NO2)C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])=C(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
COC1=C(OC)C=C(CCOC(=O)C2=C(CCN(C)C2)C2=CC=CC=C2)C=C1
[H]N(C(=O)C([H])([H])[H])C1=C(Br)C2=C(C([H])=NC([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C(C([H])=C1C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C2=C(N([H])C(=O)C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)C(=O)C([H])=C(N([H])C(=O)\C(=C(/[H])\C(\[H])=C([H])/[C@]([H])(OC([H])([H])[H])[C@@]([H])(OC(=O)N([H])[H])\C(=C([H])\[C@]1([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O
[H]ON([H])C(=O)[C@@]([H])(N([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])O[H])C([H])([H])C1=C([H])C([H])=C([H])C(O[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C2N=C3C(=C([H])N2N=C1C([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H]
[H]C1=C([H])C(=C([H])C(F)=C1[H])C1=C(SC2=NC(=NN12)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
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[H]C1=C([H])N2C([H])=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])C3=C([H])C(Cl)=C([H])C([H])=C3SC2=C1[H]
[H]N1C(=O)C2=C(C1=O)C1=C(N([H])C3=C1C([H])=C(Br)C([H])=C3[H])C1=C2C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
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[H]C1=C(C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C2C([H])=C(N([H])C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])OC3=C(Cl)C([H])=C([H])C([H])=C3[H])C([H])=C([H])C2=NC(=C1[H])C([H])([H])[H]
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[H]O[C@]([H])(C(\[H])=C(/[H])C(=C(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1C([H])([H])N1N=C([H])C([H])=C1[H])C1=NC([H])=C([H])O1
[H]N(C1=C2N=C([H])N(\C([H])=C(/[H])C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C2=NC(OC([H])([H])C([H])([H])OC([H])([H])[H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])P(=O)(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(F)=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])SC1=NC(=NC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)[C@@]2([H])N(C(=O)C([H])([H])C3([H])C4=C(C([H])=C([H])C([H])=C4[H])C([H])=C([H])C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N1N=C([H])C(=C1[H])C1=C(C(C#N)=C(S1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C(C(=O)N([H])C1=NC([H])=C([H])S1)(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])[H]
[H]C1=C([H])C(=C(C(O[C@@]2([H])C([H])([H])C([H])([H])[N@@]3C(=O)O[C@@]2([H])C3([H])[H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C2C(N([H])C3=C2C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C1[H])C([H])([H])N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@]12C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C5=C([H])C([H])=C([H])C([H])=C5[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=N2)C([H])=C1[H]
[H]N([H])C1=NC2=NC3=C(C([H])=C(C(=C3[H])C([H])([H])[H])C([H])([H])[H])N2C(N1[H])(C([H])([H])[H])C([H])([H])[H]
CC1=C(C=CC=C1CN1C2=C(SC(=N2)N2CCOCC2)C(=O)N=C1CC1=CC=CC=C1)C(F)(F)F
[H]N(C(=O)C1=C(N([H])C(=O)N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C(C(=O)OC([H])([H])[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C2=C(C([H])=NN2S(=O)(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C(=O)C(=O)[C@]([H])(N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3S2)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])SC([H])=C1[H]
[H]OC(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(OC3=C(Cl)C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C(=O)C(C1=C([H])C2=C(N([H])C(=C2C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])SC(=S)N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C(C(=C1[H])C1=NC(=C2N=NC3=C(OC([H])([H])[H])C([H])=C([H])N=C3N12)C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C([H])C(Cl)=C(C([H])=C2N2C([H])=NC([H])=C12)N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
CNC1=NC(C)=C(S1)C1=C(F)C=NC(NC2=CC=CC(=C2)S(N)(=O)=O)=N1
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(Cl)=C(S1)C1=NC(=NO1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1(C2=C([H])C(=C([H])C([H])=N2)C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1C(=O)O[H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC1=C(C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(O[C@]2([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]2([H])O[H])=C([H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)C1=C(C(=C([H])C([H])=C1[H])C([H])([H])[H])S2(=O)=O
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(S2)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])[C@@]3(C2=O)C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C(N1[H])C(\[H])=C1/C(=O)N([H])C2=NC([H])=NC(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])=C12)C([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C([H])([H])SC(=S)SC([H])([H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=NC2=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C12)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)N1N=C(C([H])=C([H])C1=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(OC([H])([H])[C@@]3([H])OC4=C(C([H])=C([H])C([H])=C4[H])N(C([H])([H])[H])C3([H])[H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]OC1=NC([H])=C([H])C2=C1C([H])=C([H])C([H])=C2O[H]
[H]N1C2=C(C([H])=C(Cl)C([H])=C2[H])[C@@]2(N([H])[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])[C@@]([H])(C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3[H])[C@@]22C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C2([H])[H])C1=O
[H]C1=NC(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C2N=C(N(C2=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([C@@]2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])[C@@]12[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C(=O)N([H])C(=O)C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)C1=NC([H])([H])C([H])([H])O1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@](C1=C([H])C2=C(N=C(N(C2=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])C2=NN([H])N=N2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)C2=C(C([H])=C([H])C(F)=C2[H])C([H])([H])[H])C([H])=C1Cl
[H]N(C1=NC([H])=NN2C([H])=C([H])C(=C12)C([H])([H])OC([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])OC1([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C2=C(O[C@]3(C([H])([H])[H])[C@@]([H])(OS(=O)(=O)C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@@]4([H])[C@](C([H])([H])[H])(C([H])([H])OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@]13[H])C([H])=C(OC2=O)C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(Br)C([H])=C2C(=N[C@]([H])(OC([H])([H])C([H])([H])OC([H])([H])[H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)[C@]1([H])C([H])([H])[C@]2([H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])[C@]2([H])C1([H])[H]
CCCCCCCN(CC1=CC=C(C=C1)N(CC)CC)C(=O)C1=CC=C(C=C1)N(C)C
[H]N(C1=NC([H])=C([H])C(=C1[H])C1=C([H])C(=NC([H])=C1[H])N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC1=C(F)C([H])=C2C(=C1[H])C([H])([H])[C@@]([H])(N([H])C([H])([H])[H])[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)N1C([H])([H])[H])C([H])([H])[H]
[H]N1N=C(C(=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C(Cl)=C(OC2=C([H])C([H])=C(O[H])C(=C2[H])C2=C([H])C([H])=C([H])C(OC([H])(F)F)=C2[H])C(Cl)=C1[H]
[H]OC(=O)C(\[H])=C(\C1=C([H])C2=C(N([H])C([H])=C2C2=C([H])C(=C([H])C(=C2OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C(Cl)C([H])=C2[H])C2=C1C([H])([H])[C@@]([H])(C2([H])[H])[C@@](F)(C1=NN=C(O1)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=C1[H])C(=O)N(C([H])([H])[H])[C@@]([H])(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(C1=C([H])N=C(S1)N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])(C(F)(F)F)C(F)(F)F
[H]N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C#N
[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])\C(\[H])=C(/[H])C2=NC3=C(O2)C([H])=C([H])C(=C3[H])C([H])([H])O[H])C([H])=C1OC([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1N([H])C1=C2C2=C(C(=O)N(N([H])C(=O)C([H])([H])O[H])C2=O)C2=C1N(C1=C2C([H])=C([H])C([H])=C1O[H])[C@]1([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]2([H])N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=CC(=C(OC)C=C1)C1=NC(=NC(NC(C)=O)=C1)C1=C(OC)C=CC(OC)=C1
[H]OC1=C([H])C([H])=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(N([H])C(=O)C2=C([H])C([H])=C(O2)C#N)=C1[H]
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C(=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N([C@]1([H])C(=O)N(C2=C(F)C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C2=C(S1)C([H])=C([H])C(Cl)=C2[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1([H])N(C(=O)C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C2=C1N([H])C1=C2C([H])=C(F)C([H])=C1[H]
[H]N(C1=NC([H])([H])C2=C1C([H])([H])N(C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C1=C2C([H])=C([H])C([H])=C([H])C2=NC(=N1)C#N
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2=O)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)C1=NN(C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C(SC([H])([H])[H])=N1
[H]N(C1=C([H])C(=NC([H])=N1)N1N=C([H])C([H])=C1[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C(C(=O)C3=C([H])C([H])=C(C([H])=C23)C(F)(F)C2=C([H])N=C([H])C([H])=C2[H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C1N([H])C1=C(C([H])=C([H])C(OC([H])([H])[H])=C1[H])C2=O)C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])S(=O)(=O)C([H])([H])[C@]23C(=O)C([H])([H])[C@]([H])(C([H])([H])C2([H])[H])C3(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C3=C([H])C(=C([H])C([H])=C3[H])C([H])([H])[H])C(=O)[C@@]1([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC(C([H])([H])[H])(C(F)(F)F)C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(C#N)=C([H])C([H])=C2O1
[H]C1=NC([H])=C([H])C(=C1[H])C1=C([H])C2=C(N=C1[H])C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]O[C@]1(C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])[C@@]2([H])N(C([H])([H])[C@]3([H])OC4=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C4OC3([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])N(C(=N1)[S@](=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N(C([H])([H])[H])C([H])([H])[H])C1=NC(=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N(N([H])C(=O)C([H])([H])SC1=NN=C(N1N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C([H])([H])Cl)C(=O)C([H])([H])[H]
[H]OC(=O)C1=C(C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C2=NSN=C2C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C2N(C(=O)C([H])([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])S(=O)(=O)C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N=C(N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(F)=C(N([H])C(=O)C2=C([H])C(=NN2C2=C(F)C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=C3[H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(O[H])N([H])C1=O
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N1C([H])=NC2=C1N=C(N1N=C(N=C21)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC([H])([H])C(=O)N1C([H])([H])[C@@]2([H])C(=C([H])C([H])([H])[C@@]2([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=N[C@@](C(=O)N1C([H])([H])[H])(C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(C#N)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[C@]1([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1F)N1N=C([H])C([H])=C([H])C1=O)S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=C([H])N2N=C(OC3=C([H])C(N([H])C(=O)C4=C([H])C(=NN4C([H])([H])[H])C([H])([H])[H])=C(C([H])=C3[H])C([H])([H])[H])C([H])=C([H])C2=N1
[H]OC1=NC(=NN1[H])C([H])([H])N(C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]C1=C(N=NN1C([H])([H])C([H])([H])[H])[C@@]1([H])OC(=O)[C@]2([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])[H])C(=O)[C@]3([H])[C@@]2(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=NC([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N(C1=O)C([H])([H])C(F)(F)F
[H]N(C1=C2N=C(N([H])C2=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(F)=C(F)C(F)=C1[H]
[H]N([H])C1=C([H])C(=NC2=C(\C([H])=C(/[H])C([H])([H])[H])C([H])=NN12)[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1N=C(N(\N=C(/[H])\C(=C(/[H])C2=C([H])C([H])=C([H])O2)\C([H])([H])[H])C1=S)C1=C([H])C([H])=NC([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C1=C([H])N=C(S1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])SC(=N1)C([H])([H])C([H])([H])C([H])([H])C1=NC2=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N2[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])\N=C1\SN(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]OC(=O)[C@@]1([H])C([H])([H])N(C2=C([H])C(N3C([H])([H])C([H])([H])N(C4=C([H])C([H])=C([H])C(=C4[H])C(F)(F)F)C([H])([H])C3([H])[H])=C(C([H])=C2C(F)(F)F)[N+]([O-])=O)C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]N([H])[C@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)C([H])([H])[N+]3=C(C([H])=C(C([H])=C3C([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@@]([H])(C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C([H])=C([H])C3=C([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(OC([H])([H])C([H])=C([H])[H])[C@]23[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)N([H])C2=C([H])C(F)=C([H])C(F)=C2[H])C1=O
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Br)C(=C1[H])N1N=C(N(C1=O)C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])N=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C(C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N([H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])=C1OC([H])([H])[H]
[H]N(C(=O)C1=NC(F)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NOC2=C([H])C([H])=C([H])C(=C12)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
CN1C2=CC=CC=C2C(CCCOC2=CC=CC3=CC=CC=C23)=C1C(O)=O
[H]N(C([H])([H])C([H])([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])[C@@]1([H])C2=C(N(C(=O)C([H])=C2[H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C2=C(C(=NN2C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=N1)C1=C([H])C([H])=C([H])N=C1F
[H]N(C(=O)O\N=C1\C2=C(N([H])C(=C2C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=S)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C1=NC(=C([H])S1)C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C(=C([H])S1)C1=NC2=C([H])C([H])=C([H])C([H])=C2S1
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[H]S\C(=N/C([H])([H])[H])N([H])N([H])C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C1=NC([H])=C(SC([H])([H])C2=NC([H])=C(O2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S1
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[O-][N+](=O)C1=CC(\C=C2/CN(C\C(=C/C3=CC(=CC=C3)[N+]([O-])=O)C2=O)C(=O)C=C)=CC=C1
[H]N([H])C(=O)C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[C@]2([H])N(C([H])([H])C3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]O\N=C1/C2=C(C([H])=C(C([H])=C2[H])C2=C([H])N(N=C2C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H]
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[H]C([H])=C(C([H])([H])[H])C([H])([H])N1C(=O)C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]C1=C([H])C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C2C([H])=C(OC([H])([H])C(=O)N3C([H])([H])C([H])([H])N(C(=O)C([H])([H])OC4=C([H])C([H])=C5C([H])=C([H])C([H])=C(N6C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C6([H])[H])C5=C4[H])C([H])([H])C3([H])[H])C([H])=C([H])C2=C1[H]
[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])[H])C([H])([H])N([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])=N1
[H]C1=NC([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C(Cl)=C2C(=O)N(C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C2=C(C(=C([H])C([H])=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1=O
[H]N(C(=O)C1=C([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2O1)C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=O)N(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=NC(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C1[H])N1C(=NC(=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N2C1=C(Cl)C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])[C@]([H])(C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=NN=C(O1)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
COC1=CC=C(C=C1)C(N1CCOCC1)C1=C(O)C2=NC=CC=C2C=C1
[H]OC(=O)[C@]([H])(N(C([H])([H])C1=NOC(=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)O[C@]2(C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])N(C(=O)C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1N=C(\C(=C(/[H])C2=C([H])N(C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C23)C([H])([H])[H])C1=O)C1=NC([H])=C([H])N=C1[H]
[H]N1N=NC(=N1)C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C(=O)C2=C([H])C(=C([H])C([H])=C12)C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(SC2=NC([H])=C([H])N2C([H])([H])[H])C(Cl)=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]N(C(=O)C1=C([H])N(C2=C([H])C(F)=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])[H])C2([H])[H]
[H]N([H])C(=NC(=O)C1=C(N([H])C(=O)C([H])([H])[H])C([H])=C(O1)C1=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C1[H])N([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1=C(SC(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)O[H])C([H])([H])C([H])([H])[H])C(O[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C(=NC(=N1)C([H])([H])[H])N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C(Br)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC([H])=C([H])C(=N2)N2C([H])=C([H])C3=C2C([H])=C([H])C([H])=C3N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O\N=C1\C2=C(C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1([H])C([H])([H])N(C2=NC(N3C([H])([H])C([H])([H])N(C(=O)C4=C([H])C([H])=C(C([H])=C4[H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])=C3C([H])=C(SC3=N2)C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=NC(=NN1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=C(C(=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=O)N(C2=C([H])C([H])=C(Cl)C([H])=C12)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=NN(N=N1)C1=C([H])C(F)=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(N([H])C(=O)C4=C(OC(=N4)C4=C([H])C([H])=C([H])C([H])=C4[H])C(F)(F)F)C([H])=N3)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])C1=C([H])C([H])=C(O[C@@]2([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
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[H]OC1=C([H])C(I)=C([H])C([H])=C1C(=O)O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(F)=C([H])C2=C1N(C1=C2C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
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[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NN=NN2C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]N([H])C1=NC([H])=NC2=C1C(=NN2C([H])(C([H])([H])[H])C([H])([H])[H])C#CC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])C([H])([H])S1(=O)=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C([H])C(=C2[H])C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CC1=CC=C(C=C1)C(=O)CC1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
[H]N(C(=O)N([H])[C@]1([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N(C1=O)C([H])([H])C(=O)N(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(N=C(S2)C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N([H])C(=O)C2=NN=NN2C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C1=C([H])C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C(=O)N([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]C([H])(OC1=NOC([H])([H])C1([H])[H])C#CC([H])([H])[N+]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1=C(C([H])=NC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)N1C(=NC2=C1C([H])=C([H])C(=N2)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]C1=C([H])N2N=C(N=C2C(=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=NN=C1[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C2=C(C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])[H])C1=C([H])C(OC(F)(F)F)=C([H])C(=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2N=C3C(=NC2=C1[H])N(C1=C3C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C([H])([H])[H])[C@@]1([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2[H])N2C([H])=C([H])C3=C(SC(=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C2=O)C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])O[C@]([H])(C2=C(OC([H])([H])[H])C([H])=C(Br)C(OC([H])([H])[H])=C2[H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]N(C1=C([H])C([H])=C([H])N2C1=NN=C2C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N(C1=N[C@@]([H])(C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C(C(=O)OC([H])([H])[H])=C(N1C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N(C1=NC(=NC(=N1)C#N)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]OC(=O)C1=NN([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C#CC1=C([H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])SC(=S)SC([H])([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
CN1CCC(COCC2=NC(=CC(=C2)C(F)(F)F)C2CC2)(CC1)C1=CC=C(Cl)C=C1
[H]\C(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C1/C(=O)C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])C1=C([H])C(N([H])C(=N[H])C([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=NC(=NC(=C1[H])C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C([H])O1
[H]C1=C([H])C(=C2OC([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N1C(=O)[C@]2([H])N(C3=C([H])C([H])=C(C([H])=C13)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C2([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])[C@]([H])(C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=C(C2=NC3=C(N2[H])C([H])=C([H])C([H])=C3[H])C(=O)N([H])C2=C([H])C([H])=C([H])C(O[C@@]3([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])=C12
[H]N1C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C3=NC4=C(O3)C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C(F)(F)C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])S[C@@]1([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]C1=C(N=C2C([H])=C([H])C([H])=C([H])C2=N1)N1C([H])([H])C([H])([H])C2(C(=O)N(C([H])([H])C3=C([H])C(=C([H])C(=N3)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(F)C(OC([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C(F)C(F)=C1[N+]([O-])=O
[H]OC(=O)C1=C([H])C([H])=C(\N=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])C(=O)N(C([H])([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]([H])(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N2C([H])([H])[C@@]([H])(C([H])([H])OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC(=O)C1=C(C2=C(C([H])=C(S2)C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])N1C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]C1=C2OC([H])([H])C([H])([H])C2=C([H])C(=C1[H])C1=NN=C(O1)SC([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=C(C([H])=C([H])C([H])=C1Cl)C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])C2(OC([H])([H])C([H])([H])O2)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=S)N([H])\N=C(\C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])/C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=NC3=C(C([H])=N2)C([H])([H])C([H])([H])C2=C3C([H])=C([H])C(N([H])C(=O)C3=C([H])C([H])=C([H])O3)=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)[C@]([H])(C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1C(=O)OC([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C2C3=C4C(C([H])=C([H])C([H])=C4C(=O)C2=C1[H])=C([H])C([H])=N3
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1N=C(C2=C([H])C([H])=C3OC([H])=C([H])C3=C12)C([H])([H])[H]
[H]C1=NN(C([H])=C1C1=NC([H])([H])C2=C1C(OC1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])=NC([H])=C2[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C(Cl)C([H])=C1Cl)C(=O)N([H])C1=C([H])C(Cl)=C(SC2=NC3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
[H]C1=NN2C([H])=C(C([H])=C([H])C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])(F)C1([H])[H])[N+]([H])([H])[H]
[H]N(C(=O)C#CC1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@]12C([H])([H])C([H])([H])C(=O)[C@]3([H])OC4=C5C(=C([H])C([H])=C4OC([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@@]235
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@@]1([H])C([H])([H])[C@]([H])(C2([H])[H])C3([H])[H])C1=C(C(=O)N2C([H])([H])C(F)(F)C2([H])[H])C2=C(S1)C([H])([H])OC([H])([H])C2([H])[H]
[H]C1=NN=C2C([H])=C([H])C(=C([H])N12)C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[C@](O[H])(C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(OC([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C(S1)N(C(=O)N(C2=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1N=NC([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C1=C([H])C(N([H])C(=O)O[C@@]2([H])C([H])([H])[C@@]([H])(OC(=O)N([H])C3=C([H])C(N([H])C(=N[H])N([H])[H])=C([H])C([H])=C3[H])[C@]([H])(N([H])C(=N[H])N([H])[H])C([H])([H])[C@]2([H])N([H])C(=N[H])N([H])[H])=C([H])C([H])=C1[H]
[H]N1C2=C(C3=C1C([H])([H])C([H])([H])N([H])C3=O)C([H])([H])C([H])([H])C1=C2N=C(N=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C(=S)N([H])\N=C(\C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])=C1Br)S(=O)(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC([H])([H])C([H])([H])N2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C(F)C([H])=C1F)[C@]1([H])C([H])([H])N(C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])[C@]2(O[C@@]([H])(C3=C2C([H])=C(Cl)C(=C3[H])C([H])([H])[H])C(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C([H])C(OC([H])([H])C([H])([H])OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])(C(=O)OC([H])([H])[H])C(=O)OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C2N=C3N(C([H])([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H]
[H]C1=C([H])C(OC(=O)N2C([H])([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])=C([H])C(Cl)=C1[H]
[H]N(N1C(=O)N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])C(=O)N([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)C1=[N+]([O-])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C#CC1=C([H])SC(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1C(=O)OC([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(N([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(C(=C1[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2C(Br)=NN3[H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2O[C@@]3([H])C(=O)C([H])([H])C([H])([H])[C@@]4(N([H])C(=O)C([H])([H])C5=C([H])C([H])=C(Cl)C([H])=C5[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C(=O)[C@@]1(C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C(F)=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])C(=O)N(C(=O)C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]1([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(=NC2=C([H])C([H])=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(F)(F)F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])S1)C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)N1C(=O)N([H])C(=C(C(=O)OC([H])([H])[H])[C@@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C(N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C(N=C1[H])C([H])=C(C([H])=C2[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N1C(=NC2=C([H])C(OC(F)(F)F)=C([H])C([H])=C12)[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(OC(=O)N(C3=C([H])C([H])=C([H])N=C3F)C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=NN1C1=C(C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C1=C(F)C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)O[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(N=[N+]=[N-])C([H])=C1[H]
[H]O[C@@]([H])(C1=C([H])SC2=C1C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3OC([H])([H])OC3=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
[H]\C(\C(\[H])=C(/[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])=C(\[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H])C(F)(F)F
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])N1C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2N(C([H])=C([H])C2=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C(=O)C2=C(C([H])=C(O[H])C([H])=C2O[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N2N1N=C(C2=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]N(C1=C2C([H])=C(SC2=NC([H])=N1)C1=C([H])SC(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C(Cl)=C1[H]
[H]C1=C([H])C([H])=C2C(S\C(=N/N(C(=O)C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[H])C2=O)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(\C([H])=C2\C3=NC4=C([H])C(Cl)=C([H])C([H])=C4C(=O)N3C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(\N=C(/C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])=N1
[H]N([H])C1=C(Br)C(=NC2=C(C([H])=NN12)C1=C([H])N(N=C1[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(OC2=C([H])C(=C([H])C([H])=C2N([H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
FC(F)(F)C1=CC=CC(SC2=NN3C(C=C2)=NN=C3C2=CC=CC(=C2)N2CCNCC2)=C1
[H]N([H])C1=N[C@@](C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])C(=O)C2=NC([H])=C(OC([H])([H])C(=C([H])[H])C([H])([H])[H])N=C2[H])(C([H])([H])[H])C([H])([H])C([H])([H])S1
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[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C#CC([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C2=C1C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C2([H])[H])C([H])([H])C([H])=C([H])[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])N=C(O2)C([H])([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=NC(=NC([H])=C1[H])C#CC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C(C#N)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])C(F)(F)F
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C(=O)C([H])([H])N([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N1N=NN=C1C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N1C([H])=C([H])C2=C(N=C([H])N=C12)N(C([H])([H])[H])[C@@]1([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N1C(=O)N(C(=O)[C@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NOC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(N([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C(C2=C1C(=C([H])S2)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])OC([H])=C1[H]
[H]N([H])C1=C2C(=NC3=C(Cl)C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
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[H]N(C(=O)O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])C([H])=C(F)N=C3[H])[C@]([H])(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
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[H]N(C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(OC2=NC([H])=C([H])C([H])=C2C2=NC(=NC([H])=C2[H])N([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
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[H]OC1=C2O[C@@]3([H])C(=O)C([H])([H])C([H])([H])[C@@]4(OC(=O)C5=NC6=C([H])C([H])=C([H])C([H])=C6C([H])=C5[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])=C1[H]
[H]C1=C(OC(=C1[H])[C@]1([H])C(C#N)=C2SC([H])([H])N(C3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])([H])N2C(=O)C1([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=NN([H])C(=N1)N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])N=C(N=C1C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC(=C(N1C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])C(=O)N1C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[C@@]2([H])Br
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(/[C@]([H])(N1C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NOC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])[C@@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=C(C(=NC(=C1[C@@]([H])(O[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
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[H]O\C(=C(\[H])C(=O)C1=C([H])C([H])=C([H])N1C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)C1=C([H])C([H])=C2N(C3=C(C2=C1[H])[C@@]1([H])N([H])[C@]([H])(C([H])([H])C1([H])[H])C3([H])[H])C([H])([H])[H]
[H]S\C(=N/C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N(C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=NN1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C(OC(F)(F)F)C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
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[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])C1=NN=C2SC([H])([H])C(=NN12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])N(C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])=C12)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C2N(C(OC([H])([H])C([H])([H])[H])=NC2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2S1(=O)=O
[H]C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=C1C(=O)OC2([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C(OC(F)(F)F)=C(C#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])N([C@]([H])(C4=C([H])C([H])=C(I)C([H])=C4[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N1C([H])=C(C(=O)C2=C3N(C([H])=C2[H])[C@]([H])(SC3([H])[H])C2=C([H])C([H])=C([H])N=C2[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(S2)C(=O)N([H])C2=C([H])C([H])=C(C(N([H])C3=NC([H])=C(C([H])=N3)C3=C([H])C([H])=C([H])N=C3[H])=C2[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(C#N)[C@@]([H])(C2=C([H])C3=C(OC([H])([H])O3)C(OC([H])([H])[H])=C2[H])C2=C(O1)C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C#N)N1C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])N=C2N=C1[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C([H])SC(=N1)N([H])C1=NC(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C([H])([H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])N=C(S1)C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H]
[H]C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])OC(=O)C1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NN=C(N=N1)C1=C([H])C(O[H])=C([H])C([H])=C1[H]
[H]C1=C(C(=O)N2C([H])([H])C3=C(OC([H])(C([H])([H])[H])C([H])([H])[H])N=C(N=C3C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C2=C1N=C(OC([H])([H])[H])C([H])=C2[H]
[H]C1=C([H])C(C2=NN=C(N2C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C1=C(C([H])=C(Cl)C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]OC([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[N@+]([H])(C2=C([H])C([H])=C(N([H])C3=NC([H])=C4C([H])=C([H])C(=O)N(C4=N3)[C@@]3([H])C([H])([H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3([H])C4([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]N(N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])C([H])([H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])S(=O)(=O)C2=C([H])N([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(Br)=C(OC2=C([H])C([H])=C(O[H])C(=C2[H])C(=O)N([H])C([H])([H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C(Br)=C1[H]
[H]N(C(=O)C([H])([H])OC(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C(S1)[N+]([O-])=O
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C(=C2C3=NC([H])=C([H])C([H])=C3C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C(=O)C(F)(F)F
[H]OC(=O)C1=C([H])C([H])=C(\C([H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C2=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C(C2=C(C([H])=C([H])C([H])=C2[H])N1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(OC3=C(O2)C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C2C([H])=C(C(=NC2=C1C#N)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])[H]
[H]OS(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N([H])C(=O)C2=C([H])C(Cl)=C(N([H])[H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2=O)=C1[H]
[H]C1=C([H])C(=C(F)C([H])=C1F)[C@]1([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])[C@]2(O[C@@]([H])(C3=C2C([H])=C(Cl)C(=C3[H])C([H])([H])[H])C(C#N)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C(=N\OC([H])([H])C1=C(N=C(S1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H])\C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])[H]
[H]N([H])C(=C(\[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])\C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])N(C([H])([H])C3=NC([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
NC1(CCN(CC1)C1=NC=NC2=C1C=CN2)C(=O)NC(CO)C1=CC=C(Cl)C=C1
[H]N1[C@]2(C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])S1(=O)=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C2=C(C([H])=C([H])C(\C([H])=C(/[H])C([H])([H])N3C([H])([H])C([H])([H])C([H])(C([H])([H])C3([H])[H])C(F)(F)F)=C2[H])C1([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1F)C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C2N(C(=O)OC(C2=C1[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C(Cl)C(Cl)=C([H])C([H])=C1[H]
[H]N1C2=C(C(=NN2C([H])([H])[H])C2=C([H])C([H])=C([H])S2)C2=C(C1=O)C([H])([H])SC2([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C(F)=C12)C(=O)[C@]1(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(O1)C(\[H])=C1/SC2=NC3=C(C([H])=C(C([H])=C3N2C1=O)C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(N([H])C2=C(N([H])[C@@]([H])(C3=C([H])C4=C(O3)C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])[H])C(=O)C2=O)C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC(C1=C([H])C(=C(C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C(OC([H])(F)F)C(OC([H])(F)F)=C1[H])C([H])([H])C1=C([H])C([H])=[N+]([O-])C([H])=C1[H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]N(C1=NC(=NN2C(=NC(=C12)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=N1
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=NC([H])=C(N([H])C2=NC([H])=NC3=C2N([H])C([H])([H])C2=C(O3)C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=N1
[H]OC(=O)C1=C([H])C([H])=C([H])C(\C([H])=C(/[H])C2=C(Cl)C([H])=C(OC([H])([H])C3=C(ON=C3C([H])([H])C([H])([H])C3=C(Cl)C([H])=C([H])C([H])=C3Cl)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])=C1[H]
[H]N(C(=O)C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N2C(=O)[C@@]3([H])[C@@]4([H])C([H])=C([H])[C@]([H])(C4([H])[H])[C@@]3([H])C2=O)C(Cl)=C1[H]
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[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
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[H]N(\N=C1/C(=O)N([H])N=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
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[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)N(C3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C([H])C(=C([H])C([H])=C1[H])N1N=C(C([H])=C1N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
COC1=CC=C2C(SC3=C2N=CN=C3NC2=CC(OC)=C(OC)C=C2)=C1
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[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C(C(C#N)=C2N1C(=O)C(=C([H])N2C([H])([H])C1=C(C#N)C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=O)OC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12
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[H]C([H])([H])[C@]1([H])O[C@@]2(C([H])([H])S1)C([H])([H])[N@]1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C1([H])[H]
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[H]C1=NC(OC2=C([H])C([H])=C(OC(=O)N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])=C([H])C([H])=C1C(F)(F)F
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[H]OC(=O)C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[H])C1=O
[H]N([H])C1=NC2=C(N=C(C3=C([H])N([H])N=C3[H])C(=O)N2C([H])(C([H])([H])[H])C([H])([H])[H])C(=N1)C([H])([H])[H]
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[H]N([H])C1=C2N=C([H])C([H])=C([H])C2=C(C(=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])[N+]([O-])=O
[H]N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=NC(OC([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
C=CC(=O)NC1=CC=C(C=C1)S(=O)(=O)N1CCN(CC1)C(=O)N1CCCCC1
[H]\C(=N/OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC([H])=C(N([H])C(=O)C2=C([H])C3=C([H])C(N([H])C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C3N2C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1=NC([H])=C([H])N1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N(C([H])([H])[H])[C@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C(=N1)C(F)(F)F)C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@@]([H])(C(=O)N(C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C2=C(N=C(N2[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=O)N(C1=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C(O[H])C([H])=C2C([H])=C1[H]
[H]O[C@@]1(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])\C(=C(/[H])C([H])([H])N1C([H])=NC3=C1C([H])=C(C(=C3[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])O2
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(N([H])S(=O)(=O)C3=C([H])C(=C([H])C([H])=C3[H])C(F)(F)F)=C2[H])N(C2=C([H])C3=C(C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1N=C(N=C1C([H])([H])C1=C([H])C([H])=C([H])C(Br)=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1(C([H])([H])S[C@@]([H])(C2=C([H])C(\C([H])=C(/[H])C3=NC4=C(S3)C([H])=C(F)C(F)=C4[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=C(C2=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=NC2=C(C#N)C([H])=NN12)C1=C([H])C([H])=C([H])C([H])=C1[H]
CCC1=NC2=C(N1[C@H]1CCC3=C1C=CC(=C3)C1=CC=CC=C1C1=NN=NN1)C(=O)N(CC1=C(C)C=CC=C1)C=C2
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])OC1=C2N=C([H])C(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])=C(N([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[H])C2=C([H])C([H])=C1[H]
[H]N([H])C(=NS(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H])N([H])[H]
[H]N1C2=C(C([H])=C(C([H])=C2[H])C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C(=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1N=C(C#N)C(=O)N(C1=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])[C@@]([H])(N(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C2=C([H])C([H])=C3C(=C2[H])C(N([H])C3(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])C1=C(Cl)C([H])=C([H])C(=C1[H])C1=NO[C@@](C(=O)N([H])C2=C([H])C([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])(C([H])([H])N([H])S(=O)(=O)N([H])[H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]2([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[C@]3(SSC2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]([H])(N([H])C1=C(N([H])C2=C([H])C([H])=NC([H])=C2[H])C(=O)C1=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C(=O)C([H])([H])\C([H])=C([H])\[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C(C(=O)OC([H])([H])C([H])([H])[H])C(=C([H])S1)C1([H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C2C(N([H])C([H])=C2C2=C([H])N=C([H])O2)=C1[H]
[H]N1C([H])([H])C([H])(OC2=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N1C2=C(C(=NN2C2=C(Br)C([H])=C([H])C([H])=C2[H])C([H])([H])[H])[C@@]([H])(S[C@]([H])(C1=O)C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C1=NC([H])=C2N=C([H])N=C(N([H])C3([H])C([H])([H])C4=C(C([H])=C([H])C([H])=C4[H])C3([H])[H])C2=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C1[H]
[H]C1=C([H])C(Cl)=C([H])C2=C1[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N3C(=O)N(C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[C@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=NN([H])C(=C2C([H])([H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2[H])C(F)(F)F)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N1N([H])C(=C([H])C1=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)N(C2=C([H])C(OC([H])([H])[H])=NC([H])=N2)C2(C1=O)C([H])([H])C([H])([H])N(C([H])([H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC([H])=C([H])S1
[H]C([H])([H])C1=C(C(=O)ON1C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)N1N=C(N=C1SC([H])([H])C(F)(F)F)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C1=NS(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C(N3N=C(C([H])=C3C([H])([H])[H])C([H])([H])[H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]N1C(=O)N(C2=C(N=C(SC3=C([H])C([H])=C([H])C([H])=C3Br)C([H])=C2[H])C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]O[C@]1(SC([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(OC(=O)N([H])C(=O)C([H])([H])Cl)[C@@]([H])(OC([H])([H])[H])[C@@]1([H])[C@@]1(O[C@]1([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC([H])=C([H])C(=N2)N2C([H])=C([H])C3=C2C([H])=C([H])C([H])=C3N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])C#N)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O\N=C(\N([H])[H])[C@]1([H])C2=C3N(C([H])([H])C([H])([H])N([H])C(=O)C3=C([H])C([H])=C2[H])[C@@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C(N([H])C(=O)N([H])C2=C([H])C(C#N)=C([H])C([H])=C2[H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(OC([H])([H])[H])=C(C(N([H])C(=O)C2=NC3=C(S2)C([H])([H])N(C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1N=NN=C1C1=C([H])C([H])=C(C([H])=C1F)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)N([H])C2=C([H])C([H])=C3C(=O)N([H])C(=O)C3=C2[H])C1=O
[H]C1=C(N=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])N(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]ON([H])C(=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1Cl
[H]C1=C(N=C(S1)[C@]1([H])OC2=C(OC1([H])[H])C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]\C(=C(\C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
NC(=O)C1=C(Br)NC(=C1)C1=CC=NC=C1