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CN1CCC(CC1)C1CCN(CC1)C(=O)[C@H](NC(=O)C1=CC=C2C(Cl)=CNC2=C1)C1=CC=CC=C1
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S=C1OC(=NN1CNC1=NC=CC=C1)C1=NC2=CC=CC=C2C=C1
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[H]O[C@@](C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])(C([H])([H])[H])C(F)(F)F
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[H]OC(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1N([H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]N(C1=C2N=C([H])C(=NC2=NC([H])=N1)C1=C([H])N=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C([H])C([H])=C4OC(=NC4=C3C([H])([H])C2([H])[H])C(F)(F)F)N1C([H])([H])[H]
[H]OC1=NN2C(=N1)C(=C(N=C2C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C(=O)[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=S)N([H])C(=O)C(=C([H])C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C1=O
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C([H])C(C#CC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])SC1=NN=C(N1C([H])([H])C([H])([H])[H])C([H])([H])N1C(=O)C([H])([H])OC2=C([H])C(Cl)=C([H])C([H])=C12
[H]N1C(=NC2=C(C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C3=C2N([H])C(=N3)C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
Cc1cnc(NC2CCCCC2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
[H]C1=C([H])C([H])=C(C2=NN=C3SC([H])([H])C(=NN23)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)N([H])C([H])([H])C1=O)C([H])([H])[H])C1=NN([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1OC([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])[C@@]3([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C2=C(S1)N(N=C2C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]OC1=NN=C(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(C(F)=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C(=N1)N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)C1=C([H])N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=C(C2=NN=C(O2)C([H])([H])[H])C(=N1)N([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])OC(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])[C@@]1([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C(C2=C([H])C3=C(N2[H])C([H])=C([H])C(=C3[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C(C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])=NN(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H]
[H]OC1=C(C([H])=C(\C([H])=C(/[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
COC1=C(O)C=CC(CCNC2=NC=C(C(=O)NCCCN3CCCC3=O)C(NC3CCCC3)=N2)=C1
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]1([H])C3=C(C([H])=C(N([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])N(N=C12)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C([H])=C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C2=C1[H]
[H]O[C@]1([H])[C@]2([H])C([H])([H])[C@]2([H])[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])C([H])([H])C([H])([H])C([H])([H])F)[C@]1([H])O[H]
[H]C1=C([H])C([H])=C(C2=NC(=C3N=NC4=C(OC([H])([H])[H])C([H])=C(F)C([H])=C4N23)C([H])([H])[H])C(=N1)C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N(C1=C(Cl)C(=C(Cl)C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])N2C(Br)=C(N=C12)C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])[H])C([H])([H])SC1=C(Br)C([H])=NC(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])[S@](=O)(=N[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C(=O)O[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])[C@]([H])(N([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C(=O)N(C1=C([H])C([H])=C2N=C(C([H])=C(C2=C1[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(C#N)=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])OC2=C([H])C([H])=C(I)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])[C@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
CC(C)C1=C(CC2=CC=C(CCCC(=O)NCC(N)=O)C=C2)C(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)=NN1
[H]OC1=C(C([H])=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C(=C23)C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N([C@@]1([H])C(=O)N(C2=C(F)C([H])=C(C([H])=C2[H])N2N=C([H])C([H])=C2C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(Cl)C([H])=C2[H]
[H]C1=C([H])N(C(C#CC2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(\N=C2/SC(=NN2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])=C(\C([H])=C2/C(=O)N([H])C3=C([H])C([H])=C(C([H])=C23)S(=O)(=O)N([H])[H])C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]O[C@@]([H])(C([H])([H])Cl)C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C(=N[C@@]([H])(N([H])C(=O)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C([H])([H])[H])C1=NC(SC([H])([H])C([H])([H])[H])=NS1
[H]SC1=NC(=NN1C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C(Cl)=C1C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(C2=C(N=O)C3=C([H])C([H])=C([H])C([H])=C3N2[H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]N(C(=S)N([H])C(C1=C([H])C(OC([H])([H])[H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C1(N([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])C3=C4C([H])=C([H])C([H])=C([H])C4=NC(=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=NC(=N1)C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C(=O)C2=C1C([H])=C([H])C(=C2[H])C([H])([H])OC1=C([H])C(=NC(=C1C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C([H])C(=C([H])C([H])=C2N=C1C([H])([H])C([H])([H])C([H])([H])[H])N(C(=O)OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C2=C(N([H])C3=NC([H])=NC(=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N([H])C(=S)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C([H])=C2N1[H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N1C(=O)C([H])([H])C([H])([H])C2=C1N=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C4C(OC([H])([H])C([H])([H])C4([H])[H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])=C2[H]
[H]OC([H])([H])[C@@]1([H])O[C@]2(OC([H])([H])C3=C2C([H])=C(C(Cl)=C3[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(C2=NC(=C3N2N=C([H])N=C3N([H])[H])C2=C([H])C([H])=C(C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C(F)=C2[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N/C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])\N([H])[H]
[H]C1=C([H])C2=C(C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2O1
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[H]C1=C([H])C(=C2N=C(N(C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])[C@@]12C3=C([H])C(OC(=O)N([H])C4=C(F)C([H])=C([H])C([H])=C4[H])=C([H])C([H])=C3N(C([H])([H])[H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C2N=C([H])C([H])=C([H])N2N=C1[H])C1=NN(C([H])=C1C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C(Cl)C([H])=C2[C@]([H])(O[H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N1C2=C([H])C([H])=C(C([H])=C2C(=C1C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C(Cl)C(=NN1[H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(F)=C(C([H])=C1[H])C1=NC2=C([H])C(O[H])=C([H])C(C#N)=C2O1
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N(C1=C(Cl)C(=C(Cl)C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])N2C(Br)=C(N=C12)C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C1=C(N(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C(F)(F)F)S(=O)(=O)C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N([H])[C@@]([H])(C([H])([H])F)C2([H])[H]
[H]OC1=C2C([H])=C([H])C([H])=C(C2=C([H])C([H])=C1[H])S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2O1)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
COC1=CC=C(CNCCCC[C@@H](NC2=CC(C)=C(F)C(C)=C2)C(=O)NO)C=C1
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N=C(N=C1C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C#N)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(OC(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=C2C(=O)C([H])=C(OC2=C1[H])C1=C([H])C([H])=C(O[H])C(O[H])=C1[H]
[H]N(N(C(=O)N([H])[C@@]([H])(C1=NC([H])=C(C([H])=C1F)C(=O)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C(F)=C([H])C(=C1[H])C(F)(F)F
[H]N1C([H])=C2C3=C(N=C([H])N=C13)C1=C(N([H])[C@@]2([H])C(F)(F)F)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2F)C2=C([H])C([H])=C([H])C(=C2N(C1=O)C([H])([H])C(=O)N1C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NN([H])N=N1
[H]N(C1=C(OC2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC2=NC(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=N2)=NC(=N1)C1=NC([H])=C([H])C([H])=N1)S(=O)(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C3=C([H])C([H])=C(O[H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]1([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])O[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)[C@]3([H])[C@]([H])(C2=O)[C@]2(OC(=O)C([H])([H])[H])C([H])=C(C([H])([H])[H])[C@@]3([H])[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C(C([H])=C([H])C([H])=C12)N(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])=C(C2=C(N=C([H])N=C12)N([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])[H])C1=C(F)C(=O)N(C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H])C([H])([H])[H]
[H]O[C@@](C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C3=C(N=C([H])N3C([H])([H])[C@]12C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])C([H])([H])C([H])([H])F)[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])C(=O)C1=C(F)C(F)=C([H])C(F)=C1F
[H]OC1=C([H])C([H])=C2C(OC([H])([H])[C@@]([H])(N3C([H])([H])C([H])([H])C(O[H])(C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])C3([H])[H])[C@@]2([H])O[H])=C1[H]
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[H]N=C(N([H])[H])C1=C([H])C(O[C@]([H])(C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2F)C2=C(C([H])=C([H])C([H])=C2[H])S(=O)(=O)N([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])C([H])([H])[C@]1([H])C(=O)N([H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]N1C(=C([H])C2=C1C([H])([H])[C@@]([H])(N([H])C2=O)C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C1=NC2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])=C2C(=N1)N([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(SC3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C3=C(N=C([H])C([H])=C3N2C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
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[H]OC([H])([H])C([H])([H])N(C1=NC2=C(N=C(N=C2C(=N1)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C([H])([H])O[H])N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])O[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C(OC([H])([H])C(=O)N3C([H])([H])C([H])([H])N(C(=O)C([H])([H])OC4=C([H])C5=C(N([H])C([H])=C5C([H])([H])C([H])([H])N([H])[H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])=C12
[H]C1=C(ON=C1C([H])([H])[H])[C@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])C([H])([H])C2=C(SC([H])=C2[H])[C@]1([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]SC([H])([H])C([H])([H])N([H])C(=O)C(=O)C([H])([H])C1=C([H])C(Br)=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1SC(=S)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[N+]([O-])=O)[N+]([O-])=O
[H]N([H])C([H])([H])C([H])([H])N([H])C1=NC2=C(SC(=C2[H])C2=C([H])C([H])=C([H])C([H])=N2)N2C1=NC([H])=C2C([H])([H])[H]
[H]C1=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=C2OC(=C([H])C(=O)C2=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1C([H])([H])[C@@]2(O[C@](C([H])([H])[H])(C1([H])[H])[C@@]1([H])C(=O)N(C(=O)[C@@]21[H])C1=C([H])C([H])=C(C#N)C(=C1[H])C(F)(F)F)C([H])([H])[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C(C([H])=C([H])C([H])=C12)N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])[N+](=C([H])C([H])=C1N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1([H])C([H])([H])[N+]1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
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[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(C([H])=C(OC(F)(F)F)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1OC(F)(F)F)C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
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[H]S\C(=N/N(N([H])[H])C1=C(F)C(F)=C(F)C(F)=C1F)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])N1C(=C([H])C(\C([H])=C2/SC(=S)N(C2=O)C([H])([H])[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N1C(=N[C@](C2=C([H])C([H])=C(F)N=C2[H])(C2=C([H])C([H])=C(F)C([H])=C2[H])[C@]1([H])C([H])([H])[H])C1=C([H])N(C(=O)C(=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[N+]([O-])=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(=O)N([H])C([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])N([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(N1N=NC(=N1)C([H])([H])[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(C2=NO[C@]3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]23[H])=C(C(C#N)=C1[H])C(F)(F)F
[H]OC(=O)C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C(=N/N([H])[H])\C1=C([H])C2=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]OP(=O)(O[H])C([H])(C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])P(=O)(O[H])O[H]
FC(F)(F)C1=CC(=CC(COCC2(CCNC(=O)C2)C2=CC=CC=C2)=C1)C(F)(F)F
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC3=NC([H])=NN3C(N([H])C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)N([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])=C([H])C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[C@]1(O[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC([H])=NN2C([H])=C([H])C(=C12)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C([H])C(=N1)C(=O)N([H])C([H])([H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C(C([H])=C3[H])N2C([H])=NN=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])[C@]1([H])O[H])C1=C([H])C([H])=C(Cl)C(=C1[H])C([H])([H])C1=C([H])N=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N=C1[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(=NN1[H])C1=C([H])C([H])=C(N([H])C(=O)OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=C(C#CC2=NC([H])=C(S2)C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=NC([H])=N1)C([H])([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C(=NC(=O)C1=C([H])C([H])=C(O1)C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(C(=O)OC([H])([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H]
[H]SC([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])S1)C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(SC2=C1C(=NC([H])([H])C1=NN=C(N21)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C#CC([H])([H])N1C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1C2=C(C3=C1C(=O)N(C(=O)N3C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C([H])N=C2[H]
[H]OC1=C([H])C([H])=C2O[C@]3([H])C([H])([H])N(C([H])([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])[C@@]3(C2=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C(SC(SC2=NN=C(SC3=NC([H])=C(S3)[N+]([O-])=O)S2)=N1)[N+]([O-])=O
[H]N(C(=O)C1=C([H])SC([H])=C1[H])C1=C([H])C([H])=C([H])C(N([H])C2=C([H])C([H])=C3C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4C3=O)=C2[H])=C1[H]
[H]N1C([H])=C(N=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=N1)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])C1=C(O[H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC(=O)C([H])([H])N(C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C3C([H])=C(OC([H])([H])[H])C([H])=C([H])C3=C2[H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C(\[H])=C(\[H])[C@@]([H])(C#CC2=C([H])C([H])=C([H])C([H])=N2)C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]N(C1=NC(=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2N([H])N=C([H])C2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(OC2([H])C([H])([H])C([H])([H])N(C3=C([H])C4=C(C([H])=N3)C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=NC2=C(S1)C(=C([H])C([H])=C2O[H])C([H])([H])C([H])([H])N([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1C([H])([H])N([H])[H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(OS(=O)(=O)C2=C([H])C(Cl)=C([H])C([H])=C2Cl)=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C(SC([H])([H])C2=NC([H])=C(O2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S1
[H]OC(C1=C([H])C(F)=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])C1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[N+]2(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C(=C([H])C(=C1[H])C1=NN=NN1C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)[C@@]1([H])[C@]2([H])C([H])([H])N(C3=C(C#N)C([H])=C([H])C([H])=N3)C([H])([H])[C@]12[H]
[H]N(N([H])C(=O)C1=C([H])C([H])=C(O1)C([H])([H])N1N=C(C(Cl)=C1C([H])([H])[H])[N+]([O-])=O)C(\[H])=C1/C([H])=C(Cl)C([H])=C([H])C1=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C2=C([H])C(=O)C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@]3(C(=O)C([H])([H])C([H])([H])[C@@]3([H])[C@@]12[H])C([H])([H])[H]
[H]OC1=NN2C(=N1)C(=C(N=C2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1
[H]OC1=C(O[H])C(=O)[C@]([H])(O1)C([H])([H])C([H])([H])C#CC1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C(C2=C([H])SC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C2=C([H])C([H])=C3OC([H])([H])C([H])([H])C3=C12
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])=NC2=C(N(N=C2C1=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)O[C@@]1([H])C([H])([H])C([H])([H])[C@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C([H])([H])N1C([H])([H])C([H])([H])[C@]2(O[C@@]([H])(C(=O)C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])SC([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])S1
[H]N([H])C1=NC(N([H])[H])=C(F)C(C2=NC(=C(N2[H])C2=C([H])C([H])=C([H])O2)C2=C([H])C([H])=NC([H])=C2[H])=C1F
O=C(NC1CCN(CCCN2C(=O)COC3=C2C=CC=C3)CC1)C1CCCC1
[H]O[C@@]([H])(C([H])([H])[H])[C@]([H])(N1C([H])=NC2=C(N=C([H])N=C12)N([H])[H])C([H])([H])OC([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=CC(NS(=O)(=O)C2=CC=C(Cl)C=C2Cl)=CC=C1OC1=CC(Cl)=CN=C1
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C3C(ON=C3C([H])([H])[H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(F)=C2[H])C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C3=C([H])C([H])=C([H])C4=C3C(=C([H])C([H])=C4[H])S2(=O)=O)C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])[C@@]([H])(C(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)C([H])([H])C1=C2N(C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])[C@]([H])(N(C([H])([H])[H])S(=O)(=O)C1=C([H])N(N=C1[H])C([H])([H])[H])C([H])([H])C2([H])[H]
COC(=O)C1=CC2=C(NC3=C2C(N)=CC=C3)C2=C1C=CN2
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2C(N([H])N=C2S(=O)(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)=C1[H]
[H]OC1=NC(=NC2=C1N([H])C([H])=C2C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])N([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C1=C([H])SC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1(C(=O)N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C(OC2=C(C#N)C3=C(N=C(S3)C([H])([H])C(=O)C([H])([H])[H])C([H])=C2[H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NN=C(O1)SC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C#N
[H]N(C(=O)C([H])([H])OC([H])([H])[H])C1=NN(C2=C1C([H])=C1C([H])=C(C([H])=C([H])C1=N2)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C2=C3C([H])=C(OC4=C(C#N)C([H])=C([H])C(=C4[H])C([H])([H])N4C([H])=NC([H])=C4C([H])([H])N(C([H])([H])[H])[C@@]([H])(C1=O)C([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C2[H]
[H]C1=C(OC([H])([H])[H])N=C2N3C(=NC(=C3C(=NC2=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H]
[H]N(C(=O)C([H])([H])Cl)C1=C([H])C(=C(S1)C1=NN=C2SC3=C(N=C4C([H])=C([H])C([H])=C([H])C4=N3)N([H])N12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C(N([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])[H])C(=O)C1=O)C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C1=NC(=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])OC1([H])C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C([H])=C(F)C(=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C2C(OC([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C2([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])O1)[C@@]1([H])OC(=O)[C@]2([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])[H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1[H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C#N)C(=C1[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(OC3=NC(=NC(=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)N([H])C([H])([H])C3=C([H])C([H])=NC([H])=C3[H])C([H])=C([H])C([H])=C2S1
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C(N([H])S(=O)(=O)C(F)(F)F)C([H])=C([H])N=C1[H]
[H]C1=C([H])C([H])=C2C(OC3=C(C([H])=C([H])C(=C3[H])C([H])([H])C([H])([H])[H])[S@@]2=O)=C1[H]
[H]N(C1=NC([H])=C([H])C(=C1[H])C1=C([H])C(=NC([H])=C1[H])N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C(=C2[H])C([H])([H])[H])C(C(=O)C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])C2([H])[H])=C1C([H])([H])[H]
[H]N(C1=NC([H])=C2C([H])=C(C(=O)N(C2=N1)C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N1C(=C2C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N1C([H])([H])[C@@]2([H])C([H])([H])N(C3=C([H])N=C([H])C(=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1N1C(=O)C(C1=O)(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N1N=C(C(=C1C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC2=C(N=C([H])N2[C@]2([H])O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])[C@@]2([H])O[H])C(=N1)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=N[N+](=NN2[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C(=C(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]OC(=O)C1=NOC(=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C#N)=C1[H]
[H]N1C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C([H])C([H])=C3[C@@]2([H])C1([H])[H])C(F)(F)F
[H]N(C1=NC([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=N1
[H]O[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C1([H])[H])C([H])([H])[C@@](N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])[C@]4([H])C([H])([H])[C@]14[H])(C3([H])[H])C2([H])[H]
[H]O[C@@]1([H])[C@@]([H])(N([H])C(=O)C([H])([H])N2C(=O)[C@@]([H])(N([H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=N[H])N([H])[H]
Cc1cnc(nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1)-c1ccccc1
[H]C1=C(N(N=C1C([H])([H])OC1=C([H])C(=C([H])C(F)=C1[H])C1(OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C([H])=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
CCN1CCN(CC1)C1=CC=C(O)C(=N1)C1=CC=C(C=C1F)C#C[C@]1(CN2CC3=C(C=C(OC)C=C3)C2=O)CC(=O)NC1=O
[H]OC(=O)C([H])([H])C([H])([H])N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=NSC2=C1C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C2=C(C([H])=C1Br)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N=C(S2)N([H])C2=NC(N([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]N1C(=S)N(C(=O)\C(=C(/[H])C2=C([H])C(=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C1=O)C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(Br)=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C12
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)OC1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C2=C([H])C(O[C@@]([H])(C3=C(Cl)C([H])=C([H])C(F)=C3Cl)C([H])([H])[H])=C([H])C([H])=C2N=C1[H]
[H]N1N=C(C2=C(N=NS2)C([H])([H])[H])\C(=C(/[H])C2=C([H])N(C3=C2C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])=C([H])C([H])=C3[H])C([H])([H])[H])C1=O
[H]N(C(=O)C([H])([H])C1=C([H])C(I)=C(OC(=O)C([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C(OC([H])([H])[H])C([H])=C([H])C2=C([H])C3=[N+](C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C31)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)[C@@]1(C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]OP(=O)(O[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=NC2=C(S1)C([H])=C(N([H])C1=C3C([H])=C(C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])=C([H])C3=NC([H])=C1C#N)C([H])([H])[H])C([H])=C2[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])C([H])(P([O-])([O-])=O)P([O-])([O-])=O
[H]N([H])C1=C(OC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])N=C2[H])N=C(C([H])=N1)C1=C([H])N(N=C1[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N
[H]O[C@@]([H])(C([H])([H])N1N=C(C2=C1C([H])([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(C(SC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C(F)(F)F)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]\C(C(=O)N1[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H])=C(\C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=C2[H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C(S1)C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1C([H])([H])C([H])([H])Cl)C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C2C(OC(=C2C([H])([H])[H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C(Cl)C([H])=C1C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(=N1)C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])[H])C2([H])[H]
[H]O[C@]1([H])[C@]2([H])C([H])([H])[C@]2([H])[C@@]([H])(N2C([H])=NC3=C(N=C(Cl)N=C23)N([H])C([H])([H])C2=C([H])C(Br)=C([H])C([H])=C2[H])[C@]1([H])O[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])N([H])C1=O)C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]21[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])S[H])C(=O)O[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2C([H])=C([H])C(=C([H])C2=C1[H])C([H])([H])N(C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3(C4=C([H])C([H])=C5C(=C(O[H])C(=O)C([H])=C5[C@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]2([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]12C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C1([H])[H])[C@]([H])(N([H])C(=O)C(OC1=C([H])C([H])=C([H])C([H])=C1Cl)(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]N1N=C([H])C(=C1[H])C1=C([H])C2=C(N=C(S2)C(=O)N(C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1N=C([H])C2=C1C([H])=C(C([H])=C2[H])C1=C([H])N(N=C1C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C(OS(=O)(=O)C([H])([H])[H])C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C2N([H])C([H])([H])C3=C(OC2=NC([H])=N1)C([H])=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C3[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]OC(=O)C1=C(SC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2N(C2=C([H])C(Cl)=C(F)C([H])=C2[H])S1(=O)=O
[H]O[C@@]([H])(C([H])([H])N(C(=O)C([H])([H])C([H])([H])N1C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])[C@@]([H])(N([H])C(=O)C([H])([H])OC1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[C@@]1([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C1=NC(=C([H])O1)C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=N1
[H]N([H])C(=O)C([H])([H])[C@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=O)N([H])[H]
[H]C1=C([H])C2=C(O1)C([H])=C1OC(=C([H])C(=O)C1=C2OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])SC2=C([H])C(O[H])=C([H])C([H])=C2S[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C1=C(N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O)C(=O)OC([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])[C@]2([H])C3=C(C([H])=C(C([H])=C3[H])[N+]([O-])=O)C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C1=C([H])C([H])=C(SC2=NC([H])=C([H])N2C([H])([H])[H])C(Cl)=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(\C([H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])C([H])=C12
[H]N(C1=NN2C(N=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1S(=O)(=O)C1=C([H])C(Cl)=C(F)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])SSC([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])O[H]
[H]C1=C(N=C2N1[C@@](C(=O)N2C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N1[C@]2([H])C3=C(N(C4=C([H])C([H])=C(C([H])=C34)S(=O)(=O)N3C([H])=C([H])C4=C3C([H])=C(F)C([H])=C4[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]C1=C([H])N(C([H])=N1)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1\C([H])=C(/[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2N1C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[P@@](=O)(OC([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)[C@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
CN1C(COC2=CC=CC=C2)=NC2=C1C(=O)N(C)C(=O)N2C
[H]C1=C(C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])N1C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])C([H])(N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C1=NC(F)=C([H])C([H])=C1[H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC(=O)C([H])([H])[C@@]1([H])N([H])C2=C(C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])N(C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(Cl)=C([H])N=C(N([H])C([H])([H])C(F)(F)C2=[N+]([O-])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C1=NC([H])=C([H])C([H])=C1F
[H]ON(C([H])=O)C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])N1C2=C([H])C([H])=C([H])C(C3=C([H])C(F)=C([H])C(F)=C3[H])=C2OC([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C(OC(F)(F)C([H])(F)F)=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C2N(C(=C(C2=C1[H])C([H])([H])C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(N=C1[C@@]1([H])C([H])([H])C([H])([H])[C@]3(OC(=O)C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C1([H])[H])C([H])=C(C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)[C@@]12[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=NN(C(=O)C2=C1C([H])=C([H])C(=C2[H])C([H])([H])OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=S)N([H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C([H])N([H])C4=C3C(=C([H])C(=C4[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]2([H])C1([H])[H])C(=O)C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)S(=O)(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)C1=C([H])C([H])=C(O1)C([H])([H])N([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(Br)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3C([H])([H])[C@@]2([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])O\N=C(/C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)C1=C(Br)C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N1CCN(C1=O)C1=CC=C(C=C1)C#C[C@]1(CN2CC3=C(C=C(OC)C=C3)C2=O)N([H])C(=O)N([H])C1=O
[H]N(C(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C2N=C(N([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1(C(=O)N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2C1=O)C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C(C([H])=C(C([H])=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=NO[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C2=NC([H])=C([H])N2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(N([H])C(=O)C2=C([H])N=C(S2)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=NN1C([H])([H])[H]
[H]OC([H])([H])[C@]1(OC(=O)\C(=C(\[H])C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C1([H])[H])C([H])([H])OC(=O)C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N(C1=NC([H])([H])C2=C1C([H])([H])N(C(=O)N([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2(C([H])([H])[H])C([H])([H])[H])C1=NC(Cl)=NC(OC([H])([H])C([H])([H])C([H])([H])[H])=N1
CC1(C)CC(CC(C)(C)N1[O])NC(=S)NC1=CC=C(C=C1Cl)S(N)(=O)=O
CC1=C([C@H](N2N=C(C=C2N1)C(F)(F)F)C1=CC=C(Cl)C(Cl)=C1)C1=NC=NN1C1=CC=CC(=N1)C(F)(F)F
[H]N1N=C(C([H])=C1C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C(=C2[H])C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])N(C2=NC([H])=C(Br)C([H])=N2)C([H])([H])C1([H])[H])S(=O)(=O)OC1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C([H])C(=C([H])N=C12)C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(O[C@@]1([H])C([H])([H])[C@@]2([H])N(C(=O)C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C(=NC2=C1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C([H])=C(C1=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C(C([H])=C([H])C([H])=C1F)C(F)(F)F
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])[C@@]([H])(C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C2=C(C1=O)C1=C(N(C3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C2C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C([H])([H])C#N)C1=C(C([H])=C([H])N=C1N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C1C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]ON([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1(C#N)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
COC1=CC(Br)=C(C=C1OC)S(=O)(=O)NC1=CC=C(C(O[C@H]2CCCN(C)C2)=C1)C(F)(F)F
[H]O[C@]([H])([C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])N([H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C2([H])N(C([H])([H])C3=C([H])C([H])=C4C([H])=C(F)C([H])=C([H])C4=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1=C([H])SC([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC2=C(C3=C(F)C([H])=C([H])C([H])=C3[H])[N+]([O-])=C([H])C([H])=C2C(=C1[H])C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3OC([H])([H])C([H])([H])OC3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])[C@]1([H])C2=C(OC([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(=C23)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C(=O)C1=C([H])N(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CCC1=NC(C(C)C)=C2C(CCC3=CC=C(C=C3)C(F)(F)F)N(CCN12)[C@@H](C(=O)NC)C1=CC=CC=C1
[H]C1=C([H])C(OC([H])([H])[H])=C2C(OC([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C2([H])[H])=C1[H]
[H]C1=C(C([H])=C2C(=N1)[C@]([H])(C1=C(C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C([H])=[N+]([O-])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=NN=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C1=NC2=C(O1)C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(C1=C([H])N(C2=C1C([H])=C([H])C(=C2[H])C1=NN([H])N=N1)C([H])([H])[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=N1)C(F)(F)F)C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])N(C(=O)C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C([H])C(F)=C(C([H])=C2N2C([H])=NC([H])=C12)N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@@](=O)(O[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(SC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=NC(=NO3)C([H])([H])[H])=NC2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(=C1[H])N1C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])N2C(=O)C([H])([H])C3(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2=O)[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])[H])[N+]([O-])=O
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])\C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C(=O)C(=C(C2=O)C2=C(C(=O)C3=C(C(O[H])=C(O[H])C([H])=C3C2=O)C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])[H])C(=C1O[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])C1=NN([H])C(=O)C2=C1N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C(N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C(=C([H])C([H])=C3N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])[N+]([O-])=O)C([H])([H])C2([H])[H])C(F)=C([H])C(=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]OC(=O)C([H])([H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])N(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])=C(C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])O2
[H]OC1=C(N([H])C(=O)N([H])C2=C(Cl)C(F)=C([H])C([H])=C2[H])C([H])=C([H])C(Cl)=C1S(=O)(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC1=C2C([H])=C([H])C([H])=C([H])C2=C2N([H])C(N([H])C3=C([H])C([H])=C([H])C(Cl)=C3[H])=C(C(=O)OC([H])([H])C([H])([H])[H])C2=C1[H]
O\C(\C=C\C1=CC=C(C=C1)[N+]([O-])=O)=C/C(=O)C1=CC=CC=C1O
[H]N(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)N([H])C2=C([H])C([H])=C3C(=O)N([H])C(=O)C3=C2[H])C1=O
[H]N(C(=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C(=O)[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])[C@@]1([H])O[H])C([H])([H])[H]
[H]C1=C(C(N2N=NC3=C2N=C(N=C3N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
COC1=CC(=CC(C(O)=O)=C1Cl)N1CCN(CC1)C(=O)CN1N=C(C(Cl)=C1C)C(F)(F)F
[H]N(C1=C([H])C(Cl)=C([H])C([H])=C1[H])S(=O)(=O)C1=C(SC(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C(N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])[H])=C2[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C1(C([H])([H])C1([H])[H])C(F)(F)F)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])S1)[C@@]([H])(OC1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=NN2C(=N1)C(=C(N=C2C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1
COC1=CC(=CC(OC)=C1OC)C(CCCNCCC1=CC(OC)=C(OC)C=C1)(C#N)C(C)C
[H]C1=C([H])C(=NS1)C(=O)[C@]1([H])N(C(=O)[C@]2([H])N(C(=O)OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=NN1C([H])([H])C1=C([H])C([H])=C(C([H])=C1Cl)C(F)(F)F)S(=O)(=O)C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C(N=C1[H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1S(=O)(=O)C([H])([H])[H])C(=O)OC([H])([H])[H])S(=O)(=O)C1=C(C2=C(S1)C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(C(=NC([H])=N1)C#CC1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1(C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C(C#N)C#N)C([H])=C1C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=NC2=NC([H])=NC2=C1N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]\C(=C1/C(=O)C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C([H])C(C#N)=C2[H])C2=C1C(C1=C(C([H])=C(C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])OC1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2=O)(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]2([H])N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C2N=C(C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=NC(=C([H])S1)C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC2=C3C(=NC([H])=N2)N(C(=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C(F)(F)F
[H]OC([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]2([H])N(C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)N([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]C1=C(SC(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(\C([H])=C(/C#N)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])C1=C([H])C(=NC(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1C#N)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C(SC(=C1[H])C([H])([H])C([H])([H])[H])C1=C(OC(=N1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=NC(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C(=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(N=C([H])C(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])=C2N([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])=C1[H]
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C([H])(C1=C([H])C([H])=C(OC([H])(F)F)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])(F)F)C([H])=C1[H]
[H]C1=C([H])[N+](=C([H])C([H])=C1N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[N+]1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\[H])C3=C(C4=C(N3[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2=C1[H]
[H]OC(=O)C([H])(C(=O)O[H])[C@@]([H])(C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@]2([H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=NC(=NC([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])OC2(C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])N=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=C3C([H])=C([H])C([H])=C([H])C3=C(N=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C(C([H])=C2C(O[C@]([H])(C([H])([H])C2=O)C([H])(C([H])([H])[H])C([H])([H])[H])=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]SC([H])([H])[C@@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])S([O-])(=O)=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N=C1OC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2C([H])=C1C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(OC1=N[H])C(OC([H])([H])[H])=C([H])C([H])=C2[H]
[H]\C(I)=C(\[H])C([H])([H])N1C(=O)N(C(=O)C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C#N)C([H])=C1[H])C(F)(F)F
ONC(=O)C1N(CCC2=C1C=CC(OC1=CC=CC=C1)=C2)S(=O)(=O)C1=CC(Cl)=CC=C1Cl
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=NC([H])=C([H])C([H])=C2C1=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(N([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C1=NC([H])=NN2C([H])=C([H])C(=C12)C([H])([H])OC([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])N([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
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[H]OC([H])([H])[C@]12C(=C([H])C([H])([H])[C@]3([H])[C@]4([H])C([H])([H])C([H])([H])C(=O)[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]13[H])[C@]([H])(O[H])C([H])([H])C([H])([H])C2([H])[H]
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[H]N(C1=NC([H])=C([H])C(=C1[H])C1=NN([H])C(=O)N1C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N=C1N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([S-])=S)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]N(C(=O)C1=C(OC([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2C(Br)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C(OC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C(Cl)C([H])=C1[H])C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(N=C([H])N(C2=O)C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])=C1[H]
[H]N(C(=O)C1=NC(SC2=NN=C([H])N2[H])=C([H])C([H])=C1SC1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C([H])S1
[H]OC(=O)[C@]1([H])N(OC(=O)C([H])([H])N2C3=C([H])C([H])=C([H])C([H])=C3C(=N[C@@]([H])(N([H])C(=O)N([H])C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])[H])C2=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(C2=NC3=C([H])C([H])=C([H])C([H])=C3\C2=N\OC(=O)C([H])([H])[H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
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[H]OC1=C([H])C([H])=C([H])C2=C1C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])F)[C@]3([H])C2([H])[H]
[H]N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])O[C@]([H])(C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)C([H])([H])C1=C(OC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1Cl
[H]N(C(=O)N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C1=NN=NN1C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])O[C@]2(OC([H])([H])[C@@]([H])(C3=C([H])C(=C([H])C([H])=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])[C@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC(=NO1)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
CN1CCC(COCC2=NC(=CC(=C2)C(F)(F)F)N2CC=CC2)(CC1)C1=CC=C(F)C=C1
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(N1C2=C(C([H])=C([H])C([H])=C2[H])C2(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=N/C1=C(C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])\N(C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])O[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])N(N1C([H])=NN=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC1=C(N(C([H])([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C12)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=NC2=C1C([H])=C([H])C(=N2)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C(C(N2C(=O)C3=C([H])C([H])=C([H])C4=C(C([H])=C([H])C(C2=O)=C34)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(N([H])C2=C3C([H])=C([H])N([H])C3=NC(=N2)N([H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C([H])S1
[H]N(C1=NC([H])([H])C2=C1C([H])([H])N(C(=O)O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C1=C(F)C([H])=NC(OC([H])([H])[H])=N1
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1Cl)C1=NC([H])=C([H])C([H])=C1[H])C1=NC([H])=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N2C([H])=C([H])C([H])=C2C1([H])[H]
[H]N1C2=C(C(=NN2C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(S[C@]([H])(C1=O)C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])ON([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(N2N=C([H])C(C3=C([H])C(=NO3)C3=C([H])C([H])=C([H])C([H])=C3[H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C(C(=O)N([H])C1=O)C1=C2C([H])=C(C([H])=C([H])C2=NC(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])=O)C([H])([H])SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])[N+]([O-])=O
[H]N1C(=O)S\C(=C(\[H])C2=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])=C(OC([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])C1=O
[H]OC(=O)C1=C([H])C(N([H])C(=O)C2=C(N=C(N2[H])[C@@]23C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C([H])N=C([H])N=C1N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C#CC1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=N1
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C3=C(S2)C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C1=NN(C2=C1C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])[H])C([H])([H])C(=O)N([H])C1([H])C([H])([H])N(C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]1([H])N2C(=O)[C@@]([H])(N([H])C(=O)C3=C([H])C4=C(C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])N(C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)N([H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C(F)(F)F)C(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
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[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C2C3=C(C([H])=C([H])C2=N1)N(C(=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2N=C1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@]1([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC(=O)[C@@]([H])(OC1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])[C@]1(N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(OC(=O)N2C([H])([H])C([H])([H])C([H])(C([H])([H])C(=O)N3C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])[C@]3([H])C4=C(C([H])=C(Br)C([H])=N4)C([H])([H])C([H])([H])C4=C3C([H])=C([H])C(Cl)=C4[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC2=NC([H])=C([H])C([H])=C2C2=NC(=NC([H])=C2[H])N([H])C([H])([H])[H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C3=C(C([H])=C2C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1[H])[N+]([O-])=O)C3([H])[H]
[H]N(C1=NC([H])=C(F)C(=C1[H])C1=NN(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(O[H])C([H])=C(\C([H])=C(/[H])C(=O)C2=C(O[H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])N(C1=O)C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H]
C(C1=CC2=CC(C[N]3=CC=CC=C3)=CC=C2C=C1)[N]1=CC=CC=C1
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C(C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
NC1=C2C(SC=C2C2=CC(NC(=O)C3=CC=CC=C3)=CC=C2)=C(C=N1)C1=CN=CC=C1
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[H]N1C(=O)N(C2=C(C(=C([H])C(OC3([H])C([H])([H])C([H])([H])N([H])C([H])([H])C3([H])[H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC(=O)C1=C([H])C([H])=C2C(N([H])C(=O)\C2=C(/N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]OC1=C2C([H])=C([H])C([H])=C([H])C2=C2C(=N1)C([H])([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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OC[C@@H](O)CONC(=O)C1=C(NC2=CC=C(I)C=C2F)C2=C(C=NS2)C=C1
[H][C@@]12CCCO[C@]1([H])C1=CC(OCCCC)=CC=C1N[C@@H]2C1CC1
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[H]N=C(N([H])[H])N([H])C1=NC([H])=C(Cl)C2=C1C([H])=C(C([H])=C2[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C([H])=C2Cl)C(=C1[H])C([H])([H])N([H])C([H])([H])[H])C([H])([H])[H]
CN1CCN(CC1)C1=CC=C(C=C1)C(=O)NC1=NNC2=C1SC(=C2)C(=O)NC1CCC2=C1C=CC=C2
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[C@@]1([H])N([H])[C@]([H])(C2=NC3=C(N=C([H])N3C([H])(C([H])([H])[H])C([H])([H])[H])C(=N2)N([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
O=C(NC1=CC=C(C=C1)C1=NC(=NC(=N1)N1CCOCC1)N1C2CCC1COC2)NC1=CN=NC=C1
[H]N([H])C(=[N+]([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(N([H])[H])=[N+]([H])[H]
[H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=C([H])C2=C([H])C(Cl)=C([H])C([H])=C12)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C(\[H])=C1/[C@@]2([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]1(N([H])[H])C1=C(N([H])C(=O)C([H])=C1[H])C2([H])[H]
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(C(C#N)=C(N1C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N(C([H])([H])[C@@]1([H])N([H])C(=O)C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=NC([H])=C(N=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC([H])=C1C([H])([H])[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C([H])([H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C1=NC(=NC([H])=C1[H])N([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(=C1[H])C([H])([H])[H]
[H]SC(=N[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2C(=O)N(C([H])([H])C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=C([H])N2C(=C1[H])C([H])=C(SC1=C2C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C(=NN1C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=N2)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC(=O)C1=C(SC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N([H])C(=O)N1C([H])([H])C2=C(C(=NN2[H])N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
CCCCOC1=CC=C(C=C1)C1=NN2C(N=C(C)C=C2C)=C1CC(=O)N(CC)CC
[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])N([C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C(Br)N=C1OC([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)N1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C([H])C([H])=C([H])S1
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NN([H])C2=C1C([H])=C(C([H])=C2[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
Cc1ccccc1CNC(=O)c1cc(c[nH]1)-c1ccnc(N)n1
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(OC([H])([H])C([H])([H])C([H])([H])[H])N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N1C(=O)C([H])([H])C([H])([H])[C@@](N2C(=O)C3=C([H])C([H])=C([H])C(=C3C2=O)[N+]([O-])=O)(C1=O)C([H])([H])[H]
[H]OC1(C([H])([H])C([H])([H])C1([H])[H])[C@]1(SC(=NC1=O)N([H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C(\[H])=C(/[H])C1=C(C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
COC1=CC2=C(CN(C[C@]3(NC(=O)NC3=O)C#CC3=CN=C(C=C3)N(C3CCNCC3)C3=CN=CC=C3)C2=O)C=C1
[H]N1C2=C(C([H])=C([H])C3=C([H])N=C(\C([H])=C(/[H])C4=C([H])C([H])=C([H])C(=C4[H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C([H])=C23)C2=C1C([H])([H])C([H])([H])N([H])C2=O
C(N1CCN(CC2=CC=C(C=C2)C2=NN=C3N2C2=CC=CN=C2NC2=C3C=CC=C2)CC1)C1=CC=CC=C1
CC1=NC=C(N1CCSC1=NN=C(O1)C1=CC=C(C=C1)C(C)(C)C)[N+]([O-])=O
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C2OC([H])=C(C2=C([H])C([H])=C1[H])C([H])([H])SC([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NN=C(O1)C1=C([H])N=C([H])C([H])=C1C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(OC(F)(F)Cl)C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]12C(=O)[C@]([H])(N(C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)O[C@]([H])(C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C([H])([H])C([H])([H])N2C([H])([H])[C@]3([H])C([H])([H])N(C(=O)C4=C(C([H])=C(N=C4C([H])([H])[H])C(F)(F)F)C([H])([H])[H])C([H])([H])[C@]3([H])C2([H])[H])C([H])([H])N(C(=O)C2([H])C([H])([H])C(F)(F)C2([H])[H])C1([H])[H]
[H]C1=C([H])C(=C([H])S1)C1=NN2C([H])=NC3=C(C2=C1[H])C(=NN(C3=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N([H])C1=NC(N([H])[H])=C2C3=C(C([H])=C([H])C2=N1)N(C(=C3[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=C([H])S1)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])[C@]2([H])C([H])([H])N(C(=O)C3=C([H])C(F)=C([H])C([H])=C3[H])C([H])([H])[C@]12[H]
[H]N1C(=O)C([H])([H])OC2=C([H])C([H])=C(C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C3=NC(=NC([H])=C23)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C([H])C(C3=C([H])N=C([H])O3)=C(OC([H])([H])[H])C([H])=C12)C1=C([H])SC2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)[C@@]([H])(N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1N([H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C([H])([H])C(=O)N([H])[H]
[H]N1C(=NC2=C1C1=N[C@@]([H])(C([H])([H])[H])C([H])([H])N1C(=O)N2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NN1C([H])([H])[H]
CCCCCCCCCCCCCC(=O)N1CCCN(CC1)C1(C(=O)NC(=O)NC1=O)C1=CC=C(OC2=CC=CC=C2)C=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(Br)=N2)C(OC([H])([H])C([H])([H])[H])=C1[H]
[H]OC([H])([H])C1=C([H])C2=C(C([H])=N1)C(=O)C(=C([H])N2C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])C1=C([H])C(OC2=C(N([H])S(=O)(=O)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(O[C@@]([H])(C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C(S1)N1C([H])=NC2=C1C([H])=C([H])C(=C2[H])C1=C([H])C(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])[C@]1([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C(=NC1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
C=CC(=O)NC1=CC=C(C=C1)S(=O)(=O)N1CCNCC1
[H]C1=NC(=C([H])C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N1C(=O)N([H])C(=O)C(N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])S3)C([H])([H])C([H])([H])C2([H])[H])(C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C(OC([H])([H])[H])N=C2N3C(N=NC2=C1[H])=C(N=C3C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1F)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=NC(SC([H])([H])[H])=N1)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N2C(=NC3=C([H])C([H])=C(C([H])=C3C2=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
OB(O)C1=CC(NS(=O)(=O)C2=CC(=CC=C2)S(=O)(=O)NC2=CC(=CC=C2)B(O)O)=CC=C1
[H]N1C(=O)C2=C(C1=O)C1=C(C3=C2C2=C([H])C(=C([H])C([H])=C2N3[H])C2=NN(C(=O)C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]N1C(=O)C(=O)C2=C1C([H])=C(Br)C(=C2[H])C([H])([H])[H]
[H]O[C@]1(C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C2=C([H])C([H])=NC(=N2)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]ON([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(C3=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])O[H])=C3[H])C(=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]C([H])=C(C([H])([H])[H])C([H])([H])N([H])C1=C([H])C([H])=NC2=C1C1=C(S2)C(=O)N(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1N=C([H])C(=C1C1=NC([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=NC2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C(N(C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=C([H])C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])=NC(=C2[H])C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H]
[H]C1=NC(C(=O)N2C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])=C(N1C([H])([H])[H])C(=O)N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1(N2C([H])([H])C([H])([H])C(F)(F)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])[C@]2(F)C([H])([H])[C@]2(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C(C(=C2O[C@@]([H])(SC2=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1=NN=C(S1)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])C1=NN(C(=O)N(C([H])([H])[H])C([H])([H])[H])C(SC([H])([H])[H])=N1
[H]N([H])C1=NN([H])C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])SC([H])=C2[H])C([H])=C1[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])[H]
[H]O[C@@](C1=NC2=C([H])C(Cl)=C(Cl)C([H])=C2N1[H])(C([H])([H])SC([H])([H])C([H])([H])[H])C(F)(F)F
[H]OC1=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(N=NC2=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C23)C([H])=C1OC([H])([H])[H])C1=NN([H])C([H])=C1C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=C(OC3([H])C([H])([H])N(C4=C([H])C([H])=C5C([H])=C([H])C([H])=C([H])C5=N4)C3([H])[H])N=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(N=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]ON(\C(S[H])=N\C([H])([H])C1=C(Cl)C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]O[C@@]1([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])[C@]1([H])N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(C2=C([H])C(OC([H])([H])[C@@]3([H])N(C(=O)C([H])([H])[H])C4=C(C([H])=C([H])C([H])=C4[H])C3([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])[S@](=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C(C([H])=C(C#N)C(=N1)N1C(=O)C(=O)N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(OC2=NN=C(C3=C2C([H])=NN3C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC2=C1C([H])([H])[C@]([H])(C(=O)C1=C([H])N(C3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C(N(C(Cl)=N1)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC([H])([H])[C@]1(OC(=O)\C(=C(\[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C1([H])[H])C([H])([H])OC(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])N(C(=S)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C(=O)C3=C([H])C(O[H])=C(O[H])C([H])=C3O2)C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])=C1[H]
[H]N=C(N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])N([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])N(C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(S1)C([H])=C(C([H])=C2[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(F)C([H])=C1[H])C(F)(F)F)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C#CC2=C([H])C3=C(C([H])=C2[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2N3C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@]1([H])N(C2=C([H])C([H])=NC(=N2)N2C([H])=NC([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Br
[H]N([H])C1=NC(=NC2=C(C(=O)N([H])C3=C([H])C([H])=NN3[H])C(=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C2C(OC(C3=C([H])C([H])=C([H])O3)=C2C2=C([H])C([H])=C([H])O2)=NC([H])=N1
[H]N(C1=NC2=C(C([H])=C1C#N)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C(N=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C#C[H])N([H])C(=O)C([H])([H])[C@]1([H])C(=O)N(C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(N([H])C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C2=NC([H])=NC(=N2)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N([H])C1=NC2=C(SC([H])=C2[H])C(=N1)C(=O)C1=C([H])C([H])=C(S1)C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C(N=C([H])N2[H])C(=O)N1[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C1=NC(=C(O1)C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C2C([H])=C(C(=O)OC([H])([H])[H])C(=O)OC2=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(\C(S1)=N\C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(OC3=NC(=NC(=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)N([H])C([H])([H])[C@]3([H])N(C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C2N([H])C1=O
[H]OC(=O)C([H])([H])OC1=C2C(=C([H])C([H])=C1[H])C([H])=C(C([H])([H])N1N=C([H])C(=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]O[C@]1([H])C([H])=C([H])[C@]([H])(O[C@]2(N(C(=O)C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H]
[H]OC1=C(N=C([H])N=C1OC1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N([H])C1=C([H])C([H])=C(N=C1C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C(C(=O)OC([H])([H])[H])C(=C([H])S1)C([H])([H])[H]
[H]N([H])C1=C(C([H])=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])\N=C(/[H])C1=C([H])OC2=C([H])C([H])=C(C([H])=C2C1=O)C([H])([H])[H]
[H]N([H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])SC(=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])N2C(=NN=C2C2=C([H])C([H])=C3C([H])=C([H])C([H])=C(OC([H])([H])C4([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C3=N2)C([H])=C1[H]
[H]N(C(=O)C1=C(Cl)C(=C([H])C([H])=C1[H])C(F)(F)F)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
COC1=CC=C2C=C(CNCCC3=CC=C(Br)C=C3)C(=NC2=C1)C1=CSC=C1
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@@]1(C2=NN=C(N2C2([H])C([H])([H])C2([H])[H])C2([H])C([H])([H])C2([H])[H])C([H])([H])[C@]([H])(F)C1([H])[H]
[H]N=C(N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C(C([H])=C(Cl)C([H])=C1OC([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]N([H])C1=NOC2=C([H])C([H])=C([H])C(=C12)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C(=C(F)C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])[C@]([H])(N(C(=O)C(\[H])=C(/[H])C4=C([H])OC([H])=C4[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
CCN[C@H](CC1=CC=C(Cl)C=C1)C1=NC2=CC=C(C=C2C(=O)N1)C1=CNN=C1
[H]OC(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])=C(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(\C([H])=C(/[H])C2=C(Cl)C([H])=C(OC([H])([H])C3=C(ON=C3C([H])([H])C([H])([H])C3=C(Cl)C([H])=C([H])C([H])=C3Cl)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])=C1[H]
[H]OC(=O)[C@@]([H])(OC1=C(F)C([H])=C([H])C(=C1[H])C([H])([H])N1C2=NC(F)=C([H])C([H])=C2C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N1C(=C([H])C(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C2C([H])=C(OC([H])([H])[H])C([H])=C([H])C2=N1
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]OC1=C([H])C(=O)C(=O)C(C2=C([H])N([H])C3=C2C(Cl)=C([H])C(Cl)=C3C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C1O[H]
[H]O[C@@]1([H])[C@@]([H])(O[H])[C@]([H])(N2C([H])=NC3=C(N=C(N=C23)N([H])C([H])([H])C([H])([H])C2=C([H])N(C([H])=N2)C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])N([H])C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(OC([H])([H])[H])N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C3OC([H])([H])C([H])([H])C3=C12
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(O[H])[C@]1([H])O[H])N1N=NC(=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]C1=C([H])C(=O)N(C1=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(Cl)=C1[H])C([H])([H])N([H])C1=C([H])C(OC([H])([H])C2(C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C(=N1)C([H])([H])C([H])([H])C1=NC(=C(S1)C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=NC2=C(N1[H])C([H])=C([H])C(=C2[H])C(=O)N1C([H])([H])C([H])([H])C2(OC3=C(C(OC([H])([H])[H])=C([H])C([H])=C3[H])C(=O)C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(N2C(=O)C([H])=C([H])C3=C2C([H])=C(C([H])=C3C2=C([H])C([H])=C(F)C([H])=C2Cl)C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]N(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN([H])C(=S)S1
[H]C1=NC(=C([H])C([H])=C1[H])C1=C([H])C([H])([H])C([H])([H])N(C2=NN=C(S2)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])N(C(=O)C(OC2=C([H])C([H])=C(C([H])=N2)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(F)=C([H])C(=C1[H])C1=C(C#N)N(C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2C([H])([H])C(=O)N(C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]C1=NC2=C(N=C(C(=O)N2[C@]([H])(C([H])([H])OC([H])([H])[H])C2([H])C([H])([H])C2([H])[H])C([H])([H])[H])C(=C1[H])C1=C([H])C(F)=C(OC([H])([H])[H])C([H])=C1Cl
[H]OC(=O)C1=C(C([H])=C([H])C(=C1[H])C(=O)[N+]1=C([H])C([H])=C([H])C(=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[H])N([H])[H]
[H]C1=C(N=C(S1)C([H])([H])[H])C#CC1=C([H])N=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(N=C(S2)N([H])C2=NC([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]OC(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(S[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1N=C([H])C2=C1C([H])=C([H])C(=C2[H])N1C([H])=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C1=O
[H]N(C1=NC2=C(S1)N=C([H])N=C2N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=NC([H])=C([H])C([H])=C1C(F)(F)F
[H]N(C1=NC([H])=C2C(=O)N(C3=NC4=C(C([H])=C([H])C([H])=C4[H])N3C2=N1)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C(C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N1C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C(OC2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC2=NC([H])=C(Br)C([H])=N2)=N1
[H]OC([H])([H])C([H])([H])C([H])([H])N1C(=O)[C@]([H])(N([H])C(=O)C2=C([H])C3=C(SC(Cl)=C3[H])N2[H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C2=C([H])C(F)=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(N([H])C(=O)[C@@]2([H])ON=C(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C2([H])[H])C([H])=C1[H]
[H]OC([H])([H])C(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])(C([H])([H])O[H])C([H])([H])O[H]
[H]N(C1=C2N=C([H])N([H])C2=NC([H])=N1)[C@]([H])(C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)C1([H])[H])C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])[C@]([H])(C(=O)OC([H])([H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]N(C1=NC([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N([H])C([H])([H])C2=C([H])C([H])=C([H])O2)=C([H])C(=N1)C(F)(F)F
[H]OC([H])([H])[C@]1([H])O[C@@]([H])(N2C([H])=C(C(=S)N([H])[H])C3=C2N=C([H])N=C3N([H])[H])[C@]([H])(O[H])[C@@]1([H])O[H]
COC1=CC=C(NS(=O)(=O)C2=C3C=CC=C(N(C)C)C3=CC=C2)C=C1N1CCNCC1
[H]N(C1=C([H])C(=O)C(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])=C([H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]O[P@@](=O)(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]N(C(=O)C1=C([H])C(=NN1C1=C([H])C([H])=C2C([H])=C(Cl)C([H])=C([H])C2=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])SC1=NC(=O)C2=C(N1C([H])([H])C(=O)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(O1)C1=NC(=NC2=C1C([H])([H])C1=C2C([H])=C(C([H])=C1[H])C([H])([H])[H])N([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NOC2=C([H])C(=C([H])C([H])=C12)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
Cc1cnc(Nc2ccccn2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
[H]ON([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C2=C(C([H])=C1[H])N(C([H])([H])C1=C([H])C(O[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])[C@]([H])(N2[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]C1=C(N=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C([H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]