[H]C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[C@@]1([H])O[C@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C3=C1C([H])=C([H])C([H])=C3[H])C(=O)N([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])=[N+]([H])[H]
[H]OC1(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])OC2=C([H])C([H])=C3C(=C2[H])C([H])=C(C([H])=C3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(OC([H])([H])[C@@]2(OC3=C([H])C(=C([H])C([H])=C3N(C([H])([H])[H])C2([H])[H])N(C(=O)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=C(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3C2=O)=C1[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])S1)[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])=C2[H])[C@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=NN([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(N=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])[C@]([H])(F)C2([H])[H])=C1[H])C1=NC([H])=C(F)S1
[H]C1=C([H])C([H])=C(O1)C([H])([H])N1C2=C(N(C(=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(=O)N(C1=O)C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C(N([H])C2=C([H])C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C3=O)=C1[H]
[H]OC(=O)C1=C(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C2O[C@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(C([H])([H])C([H])([H])C1=C([H])C([H])=C(N=C1[H])C1=NN=NN1[H])C([H])([H])[C@]([H])(C1=C(N([H])C2=C1C([H])([H])N(C(=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1C(F)(F)F)C([H])([H])C2([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])[C@]21[H]
[H]OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(C(Cl)=C([H])C([H])=C1N([H])C(=N\C#N)\N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])[C@]([H])(C(=N\OC([H])([H])C([H])([H])OC([H])([H])[H])\C([H])([H])N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(Cl)=C2[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C([H])C1=O
[H]N(C1=NN=C(C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C([H])N(N=N2)C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3S2)=C1[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NN(C(=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NC([H])=C([H])C([H])=C1[H])[C@@]([H])(C1=NN=C(N1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
CCC1=NN2C(=C1)C(=CC=C2OC)C1=NN(CCCCOC2=CC=C(C=C2)C2=NNC(=O)CC2C)C(=O)CC1
[H]O[C@]([H])(C([H])([H])N([H])[C@]([H])(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])N(C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=S)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(O[H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C1=NN([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C1=C([H])N=C([H])C(=N1)N([H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=N1)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C(N=C1OC([H])([H])[H])N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(SC2=C([H])C(OC3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C([H])C([H])=C2[H])C(=C1C(F)(F)F)C(F)(F)F)C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(=NC2=C1C([H])=C(C(F)=C2[H])C(F)(F)F)N1C([H])([H])C([H])([H])[C@]2(C(=O)N(C3=C([H])C(Cl)=C(F)C([H])=C3[H])[C@@]2([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C(N(C3=C1C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[H])C2([H])[H]
[H]C1=C([H])C([H])=C(OC2=C([H])C([H])=C3C(OC(=O)C(=C3C([H])([H])[H])C([H])([H])[H])=C2[H])C([H])=C1[H]
[H]N1C2=C(C([H])=C(Cl)C([H])=C2[H])[C@@]2(N(C([H])([H])[H])C([H])([H])[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)[C@]22C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C2([H])[H])C1=O
[H]C1=C(N2N=C(OC([H])([H])[H])C(N(C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2S1)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1Cl)C([H])([H])OC([H])([H])[H]
[H]OC(=O)[C@@]([H])(\N=C1/C(O[H])=C(O[H])\C/1=N/C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC2=NC([H])=C([H])C([H])=N2)C([H])=C1[H]
[H]N1C(=O)C2=C(C3=C(N(C4=C([H])C([H])=C(C([H])=C34)C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C3=C2C2=C([H])N(N=C2C([H])([H])C3([H])[H])C([H])([H])[H])C1([H])[H]
[H]C1=NC(C2=C3N=C(C([H])=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1I)C([H])([H])[H]
[H]ON([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C2=C1N=C([H])C([H])=C2[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=NC(=C([H])C2=C1[H])C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)N=C([H])C([H])=C2[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])C(F)=C3[H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])\N=C(/N([H])C#N)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])\N=C(/N([H])C#N)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C2N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C3=NOC(=N3)C3=C([H])N=C([H])S3)C(F)=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])[C@@]2(C(=O)OC([H])([H])[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C(N([H])C([H])([H])C#CC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2OS(=O)(=O)C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(SC2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C(=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2N(C(=O)OC2=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(S1)C([H])=C(N([H])C1=C3C([H])=C(C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C4([H])[H])=C([H])C3=NC([H])=C1C#N)C([H])([H])[H])C([H])=C2[H]
[H]N(C(=O)[C@]([H])(N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NO1)[C@]([H])(C(=O)N([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C1=C([H])C([H])=C(\C([H])=C(\C([H])([H])[H])C([H])([H])C([H])([H])C2=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C2=C(O[C@@]([H])(C(=O)OC([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2S1
[H]C1=NC([H])=C([H])C(=C1[H])C1=C2C([H])=C([H])C(=C([H])N2N=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C2=C(C([H])=C1[H])C1=NC3=C([H])C([H])=C(F)C([H])=C3C(C([O-])=O)=C1C([H])([H])C2([H])[H])C(F)(F)F
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[H]OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=N2)C(=O)N([H])C([H])([H])C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C3F)C3=C([H])C(F)=C([H])C([H])=C3C2=O)C([H])([H])C1([H])[H]
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[H]N([H])C1=C2C(SC(=C2C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C([H])=C([H])C([H])=C3Cl)C([H])=C2[H])C([H])([H])[H])=NC([H])=N1
[H]N(C1=NC(=C([H])C([H])=N1)N1C([H])=C([H])N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])[N+]([O-])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[C@]1(O[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(Cl)=NC([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C(Cl)=C(OC2=C([H])C([H])=C(O[H])C(=C2[H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(Cl)=C1[H]
[H]C1=NC(=C(C([H])=C1[H])C1=NC(=C2N1C1=NC(OC([H])([H])[H])=C([H])C([H])=C1N=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1C1=C([H])C(=NO1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])N2C(=O)N(C(=O)[C@]12[H])C1=C(C(Br)=C(C#N)C([H])=C1[H])C([H])([H])[H]
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[H]C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=NN=C(N2C([H])([H])C1([H])[H])C(F)(F)F)[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)[N+]([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C(F)=C([H])C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=NN(C1=O)C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])C([H])=C([H])N=C2[H])=C([H])C([H])=C1[H]
[H]N(C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1=C([H])OC([H])=C1C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C1=C2C([H])=NN(C2=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(OC2=C([H])C3=C(OC(=N3)N([H])C3=C([H])C([H])=C([H])C(=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])=C([H])C([H])=N1)C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(C(=O)N([H])C3=C2C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])[C@@]1([H])C2=NC([H])=C(N2C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C(F)=C2F)C([H])([H])C1([H])[H])C1(C([H])([H])C1([H])[H])C(F)(F)F
[H]N1C2=C([H])C(=C(C([H])=C2N=C(C2=C([H])C([H])=C([H])C(=C2[H])C2=C([H])C(=NC([H])=C2[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=O)C([H])([H])[H])C(F)(F)F
[H]OC(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(C([H])=C([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
NC1=NC(O)=CC(=N1)C1=CC(C#N)=C(OCC2=CC=C(F)C=C2C(F)(F)F)C=C1
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[H]N=C1N([H])[C@](C(=O)N1C([H])([H])[H])(C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])N([H])C(=O)C1=C2N=C(N(C2=C([H])C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])[C@@]1(O[H])C2=C(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])=C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(Cl)=C2[H]
[H]N([H])C([H])([H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])S(=O)(=O)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C(=O)C1=C(N(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C(OC([H])([H])[H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C#N)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1F
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[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
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[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])[C@@]1([H])ON=C(C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C1([H])[H]
[H]C1([H])N(C([S-])=S)[C@]([H])(C([O-])=O)C([H])([H])C1([H])[H]
CN1C2=C(C=CC(=C2)C2=CC=CC(Cl)=C2)C2=C1C(=O)N(C)C(=O)N2C
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[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C(OS(=O)(=O)N([H])[H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N(C(=O)C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])[C@]([H])(C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C2([H])[H]
O=C(NCc1ccc2OCOc2c1)c1cc(c[nH]1)-c1ccnc(Nc2ccccc2)n1
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[H]C1=C([H])C(F)=C(F)C(=C1[H])C([H])([H])N(C1=C([H])C([H])=C(C#N)C(Cl)=C1[H])[C@]1([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@@]1([H])C([H])([H])N(C(=O)C([H])=C([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
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[H]OC1=C([H])C([H])=C(\C([H])=C2\C(=O)N([H])C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1[H]
[H]N([H])C(=O)C1=C(N([H])[H])C2=C(S1)N=C([H])C([H])=C2OC([H])([H])C([H])([H])[H]
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[H]N(C(=O)C([H])([H])N1C2=C(C([H])=C(Cl)C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
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[H]S\C(=N\C([H])([H])C1=C([H])N=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H]
[H]OC(=O)C(\[H])=C(\C(\[H])=C(/F)\C(\[H])=C(/C1=C([H])C(=C([H])C(=C1OC([H])([H])C([H])(F)F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])/C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C([H])N([H])C4=C3C(=C([H])C([H])=C4[H])[C@@]2([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])[C@]1([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N([H])C2=C(C([H])=C(Br)C([H])=C2[H])[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C2=C(C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]C(C1=C([H])C([H])=C(O1)C([H])([H])[H])=C1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
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[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])=NC2=C([H])N=C(C([H])=C2C1=O)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C1=NN(C2=C1C(=NC([H])=N2)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])N(C(=O)C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C(C#N)=C2[H])C([H])([H])C1([H])[H]
[H]C1=NOC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(SC([H])=C1[H])N([H])C(=O)C([H])([H])C1=C([H])C2=C(OC([H])([H])C([H])([H])C([H])([H])O2)C(Cl)=C1[H]
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[H]SC1=NN=C(S1)N([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C(F)=C(F)C(F)=C1F
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[H]N(C(=O)[C@]1([H])N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])[C@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N2C(=NN=C2C(F)(F)F)[C@@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])C1=C(C(=NC([H])=N1)C#CC1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(N([H])[H])=C([H])C([H])=C1[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N1C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C1([H])[H]
[H]N(C(=O)N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(OC(=O)C3=C(C([H])=NC([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])C1=NC([H])=C(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=NC2=C1C([H])([H])[C@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C#N)C(=N/C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])\N([H])C1=C([H])C([H])=C(C2=C([H])N=C([H])O2)C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])[C@]1([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=N1)C1=C([H])N=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C(=O)OC1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=N1
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[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=C([H])C2=C1N=C(N=C2[H])N([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])[H]
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[H]C1=C(N=C(Br)S1)C#CC1=C([H])C(C#N)=C([H])C(F)=C1[H]
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COC1=C(C=CC=C1)C1=CN2C(=N1)N=C(C)C(CN)=C2C1=CC=CC=C1Cl
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[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C([H])C([H])=C1F
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[H]C#CC1=C(OC([H])([H])[H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C(Cl)=C([H])C([H])=C2[H])C1=O
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[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])C(=O)C1=NN(C(=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]N(C(=O)C1=C([H])SC(=N1)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(Cl)=C(OC2=C([H])C([H])=C(N([H])C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C(Br)=C2[H])C(Cl)=C1[H]
[H]OC(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C#N)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N(C(=O)C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])[C@@](O[H])(C([H])([H])N([H])C(=O)C1=C(N([H])[H])N(N=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(F)(F)F
[H]N(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C2C(=C1[H])C1=NO[N+]([O-])=C1C([H])([H])C2([H])[H]
[H]N(C(=O)[C@]12C([H])([H])C([H])([H])[C@](C([H])([H])[H])([C@]1([H])Br)C2(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N(C([H])([H])[H])[C@@]1([H])C([H])([H])N(C2=NN=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])C1(C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1[H])C1=NC([H])([H])C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C(C#N)=C(C([H])=C1[H])C1=NOC2=C([H])C(O[H])=C([H])C([H])=C12
CC1CN(C)S(=O)(=O)C2=CC=C(N)C=C12
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C2(C(=O)N(C(=O)C2([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(C2=C3N=C(C([H])=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C4([H])C([H])([H])C4([H])[H])N3N=C2C([H])([H])[H])[S@](=O)C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C([H])([H])[H])[C@]1(C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C2([H])N(C([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C(Cl)C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=C(\[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)\C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C2C(SC3=C([H])C([H])=C(Cl)C([H])=C3[H])=C([H])N([H])C2=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN=C(O1)C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N(C2=NC([H])([H])C([H])([H])N2C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]C1=C([H])[C@]2(C(=C([H])C1=O)[C@]([H])(OC([H])([H])C#CC([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])C([H])([H])C(=O)[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H])C([H])([H])[H]
[H]OC1(C(=O)N2C([H])([H])C([H])([H])C([H])(C(=O)N3C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C4=C([H])C([H])=C(C([H])=C4[H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C([H])([H])[H])[C@]([H])(C4=C([H])C([H])=C(Cl)C(Cl)=C4[H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C(C2=C(N([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C1=C2C([H])=C(SC2=NC([H])=C1C#N)C1=C(C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(O1)C(\[H])=C1\C(=O)N([H])N(C1=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1(C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)[C@]1([H])C([H])([H])[C@]2([H])C([H])([H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]OC(=O)[C@]12C([H])([H])C([H])([H])[C@@]([H])(C(=C([H])[H])C([H])([H])[H])[C@]1([H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])\C(=N/OC(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C12
[H]OC1=C([H])C2=C3[C@](O[H])(OC2=C([H])C1=O)C([H])([H])C([H])([H])[C@]1([H])[C@]3(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]2([H])N3C4=C(C([H])=C([H])C([H])=C4[C@@]2([H])C1([H])[H])C([H])([H])C3([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C2=C1N=C(N2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C(=O)C1(C2=C([H])C(OC([H])([H])C3=C([H])C4=C(C([H])=C3[H])N(C(=O)C([H])=C4[H])C([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(N2C([H])([H])C([H])([H])N(C([H])([H])C3=C(F)C([H])=C([H])C([H])=C3F)C([H])([H])C2([H])[H])=C2C(=O)N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
CN(CC1=CC=C(C=C1)C1=NCCN1)C(=O)\C=C\CN(C)S(=O)(=O)C1=CC=C(Cl)C(C)=C1Cl
COC1=CC=CC=C1NC(=O)C1=NC2=C(NS(C)(=O)=O)C=CC=C2C(O)=C1
[H]N([H])C1=NC(N([H])[H])=C2C(=N1)C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1(OC([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=N2)C(=C1C([H])([H])[H])[C@]1([H])C([H])([H])N(C(=O)C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=NN1[H])C([H])([H])O[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C(N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C([H])C(=C2[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])SC1=C(C(=O)C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)C([H])=C2O1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])[C@]2([H])C3=C([H])C(OC([H])([H])C([H])([H])[H])=C(Cl)C([H])=C3[C@]([H])(C([H])([H])[H])[C@]2([H])C1([H])[H]
[H]OC1=NC2=C([H])C(Cl)=C(C([H])=C2C(OC([H])([H])C([H])([H])[C@@]2([H])N([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)[N+]([O-])=O
[H]N1C2=C(C([H])=C1C1=C([H])C3=C(N([H])C1=O)C([H])=C([H])C([H])=C3[H])C([H])=C(C([H])=C2[H])S(=O)(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])C1=C(C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(OC([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=NC(C2=NN=C(S2)C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC2=C([H])C([H])=C(Cl)C([H])=C2C(=N[C@@]1([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N2C([H])=C([H])N=C2C(=N1)N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C1=C(C([H])=C2N(C1=O)C([H])([H])C1=C2N=C2C([H])=C([H])C([O-])=C([H])C2=C1[H])[C@](O[H])(C([O-])=O)C([H])([H])C([H])([H])[H]
[H]N([H])C1=N[C@@](C2=C(F)C([H])=C([H])C(=C2[H])C([H])([H])C(=O)C([H])([H])SC2=C([H])C(=NC(=N2)N([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])S1
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])N1C([H])=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]ON(C(=O)N([H])[H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C3=C([H])C4=C(C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(C#N)=C(OC([H])([H])[H])C([H])=C1SC([H])([H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)O[C@]([H])(C([H])([H])N1N=C(C2=C1C([H])([H])C([H])([H])N(C(=O)N([H])[H])C2([H])[H])C1=C([H])C([H])=C(I)C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])[C@]4(OC(=O)N(C([H])([H])C5([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C5([H])[H])C([H])([H])[C@@]4([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
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[H]N1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C(=O)OC([H])([H])C([H])([H])OC(=O)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
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[H]OC1=C([H])\C(C([H])=C([H])C1=O)=C1\N([H])N2C(SC1([H])[H])=NN=C2C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC1=C(C([H])=C2C(N([H])N=C2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2Cl)=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(F)(F)F)C([H])([H])C([H])([H])C1=C(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])C([H])([H])C3=C12)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C2N=C(N([H])C2=C([H])C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=NC(=NN1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(=O)OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Cl)C(=O)N([H])N=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC(Cl)=C1C([H])([H])[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(OC3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])N=N2)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
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[H]OC(=O)C([H])([H])OC1=C([H])C(O[H])=C(C([H])=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]ON(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=NC(=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(S1)[C@]1([H])N(N=C(C2=C(F)C([H])=C([H])C(F)=C2[H])C1([H])[H])C(=O)C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C(C([H])=C2[H])S(=O)(=O)C2=C([H])C(Cl)=C([H])C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]N1C2=NN(C([H])=C2C(=NC2=C1C(Cl)=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C(=C([H])C2=C([H])C([H])=NC([H])=C12)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OC(=O)C1=C([H])C(=NO1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(OC([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C2N([H])C(=O)C([H])([H])C2=C1[H]
[H]C([H])=C([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])=C(C(=O)N2C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C(C([H])=C(C([H])=C1C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NN=C(C([H])=C1[H])N1C([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=C2C([H])=C([H])C([H])=C(OC3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])N2N=C1C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])[C@@]1([H])[C@]([H])(Cl)C([H])([H])[C@]([H])(O[H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])N1C(=S)SC2=C1N=C([H])N1N=C(N=C21)C1=C([H])C([H])=C([H])O1
[H]N1C(=NC2=C([H])N=C3C([H])=C(Br)C([H])=C([H])C3=C12)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2=O)C1=C([H])C(O[H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@]1([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]1([H])O[C@@]([H])(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H]
[H]N([H])C1(C([H])([H])C2=C(OC(F)(F)F)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2C([H])=C([H])N3[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C2C3=C(C([H])=C([H])N=C13)C1=C(N([H])[C@@]2([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
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[H]N(C([H])([H])C([H])([H])N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]1([H])C2=C([H])C([H])=C([H])C(Cl)=C2C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2OC([H])([H])[H])C(=N1)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1N=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(Cl)S2)C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12
[H]N1C([H])([H])C([H])([H])[C@@]([H])(C2=C(OC([H])([H])[H])C([H])=C([H])C3=C2C([H])([H])C([H])([H])C3([H])[H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC2([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(\C([H])=C(/[H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2C([H])([H])[H])C([H])=C([H])S1
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[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(N=N1)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(N1C([H])([H])[H])C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]\C(=N/N1C([H])=NN=C1[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1O2)C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C(Cl)S1)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C([H])N=C1[H]
[H]OC(=O)[C@]([H])(N([H])P(=O)(OC([H])([H])C([H])([H])[H])OC([H])([H])C([H])([H])[H])C([H])([H])N([H])C(=O)C([H])([H])[C@]1([H])ON=C(C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])N=C3C([H])=C2[H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(I)C([H])=C(Cl)C2=C1N=C([H])C([H])=C2[H]
[H]N1C2=NC([H])=C(Cl)N(C2=O)C([H])([H])C(=O)N([H])C([H])([H])C2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C([H])C(Cl)=C2[H]