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[H]O[C@@]12[C@@]([H])(OC([H])([H])[H])[C@@]3([H])C4([C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])[C@]3(C([H])([H])OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N1C(=O)C([H])([H])[C@@]([H])(C1=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@]4([H])OC([H])([H])[H])[C@]1([H])C([H])([H])[C@@]3([H])[C@]([H])(OC([H])([H])[H])[C@]1([H])[C@]2(O[H])C([H])([H])[C@]3([H])OC([H])([H])[H]
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[H]C1=C([H])C(=C([H])S1)C1=C([H])C2=C(F)C([H])=C([H])C([H])=C2N=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(Br)=C(N([H])C(=O)C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=NN2C([H])=C(C([H])=NC2=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
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[H]N(C1=C([H])C([H])=C(F)C(Cl)=C1[H])C1=C2C([H])=C(N([H])C([H])([H])C3=C([H])C([H])=NN3C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C(Br)C2=NC([H])=C1C#N
[H]N([H])C1=NC(=C([H])N1C([H])([H])[H])[C@]1(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]N(C1=NC([H])=C(Cl)C([H])=C1C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(F)=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C(=C(SC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1C1=NN(C2=C1C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]OC([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])SC1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C(=O)N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N1C([H])=C(C(=O)[C@@]2([H])N([H])[C@]([H])(SC2([H])[H])C2=C([H])C([H])=C([H])N=C2[H])C2=C1C([H])=C([H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(C2=NC(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(SC([H])([H])[H])=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=C([H])C([H])=NC(=N2)N([H])C(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C([H])=C1[H]
C[Si](C)(C)CCOC(=O)CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(O[H])C([H])=C2C3=C(C4=C(N3[H])C([H])=C(C([H])=C4[H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C2=C1[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])=C(F)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C2C(OC(=C2C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C(Cl)C([H])=C1C([H])([H])OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C(=O)[C@]1([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1([H])[H]
[H]OC([H])([H])C([H])([H])\N=C(\N([H])C#N)N1C([H])([H])C([H])([H])C(=C2C3=C(C([H])=C(Br)C([H])=N3)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[S@@](=O)C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
O=C1CCCC2=C1N=C(OCCCN1CCCCC1)S2
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C(F)C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1C(=O)N([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])N(N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C1=NOC(=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C([H])N=C(S1)[C@]([H])(OC([H])([H])[H])C1=C([H])C(OC([H])([H])C2=C([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C2C([H])=C(N3[H])C2=C([H])N=C([H])C([H])=C2[H])C(F)=C1[H])C(=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C([H])=C2C([H])=C(C(=O)C([H])([H])[H])C(=O)OC2=C1[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C([H])=C(Cl)C(=C2[H])C([H])([H])C2=NN=C(S2)C2=NN(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C([H])=C(C(F)=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])N(C([H])=N1)C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]O[C@]([H])(C([H])([H])N([H])[C@]([H])(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)N([H])C1=C([H])C([H])=C2C(N([H])C3=C2C([H])=C([H])C(=C3[H])C(F)(F)F)=C1[H]
[H]N(C1=NC([H])=NC2=C([H])C([H])=C(N([H])C([H])([H])C([H])([H])Cl)C([H])=C12)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC1=C(F)C(F)=C(C(F)=C1F)C([H])([H])N(N1C([H])=NN=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C2=NC3=C(N2[H])N(C(=O)N(C3=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(C([H])=C([H])C(=C2[H])C([H])([H])[H])[N+]([O-])=O)C([H])=C1[H]
[H]\C(=C1/C(=O)N2C(=C([H])S[C@]12[H])C([O-])=O)C1=NN2C(=C1[H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C([H])N2N=C(N=C12)N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
CC(C)(C)OC(=O)N1CCC(CO[C@H]2CC[C@@H](CC2)C2=CC=C(C=C2F)S(C)(=O)=O)CC1
[H]OC(=O)C([H])([H])[C@@]1([H])C([H])([H])OC2=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C(=N[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])=C2C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C(N=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N1N=C(C2=C(C1=O)C([H])([H])C([H])([H])C([H])([H])N2[H])C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C(OC(=O)C([H])([H])[H])=C([H])C([H])=C1S2(=O)=O)C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2N([H])C([H])=C([H])C2=C1C([H])([H])[H])C1=C(C#N)C([H])=NC([H])=C1C1=C([H])C([H])=C(S1)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(O[C@]([H])(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])[C@]([H])(C2=O)C([H])([H])[H])=C1[H]
[H]N(C1=NC(N([H])C2=C(C([H])=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])=C(Cl)C([H])=N1)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N(C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1N=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])N=C(S1)N([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])([S@@](=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[S@](=O)C([H])([H])[C@]([H])(N([H])C1=O)C(=O)O[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C(OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N([C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])C(N3C(=O)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N([H])C(=O)[C@]1(N([H])[H])C([H])([H])[C@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C1([H])[H]
[H]C([H])=C([H])C(=O)N([H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C([H])=C(OC([H])([H])C4=NC([H])=C([H])C([H])=C4[H])C(Cl)=C3[H])C2=C1[H]
[H]C([H])=C([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]N1N=C(N(C1=S)C([H])([H])C([H])([H])[H])C1=C([H])SC(=C1[H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2N([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])C3=NC4=C([H])C(=C([H])C([H])=C4N3[H])C(=N[H])N([H])[H])=NC2=C1[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(N=C2[H])N([H])C([H])([H])C2=C(F)C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C(F)=C2C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C2C([H])=NN1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]C1=C([H])C([H])=C(OC([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C3=NN=C(C4=C([H])C([H])=C(C([H])=C4[H])C([H])([H])[H])C4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C2N(C([H])=NC2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C#N)C([H])=C(F)C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2OC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C(OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N([H])C2=NN=C(Br)S2)C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])=C(C2=C1C(Cl)=C([H])C([H])=C2[H])C([H])([H])N(C(=O)C1=C(N=C([H])S1)C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=NC3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=C(N=C(O1)C1=C([H])C([H])=C([H])S1)C#N)C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2N2C(=NC([H])=C12)C([H])=O)C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C(=C1[H])C([H])([H])N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)N([H])C1=C([H])C(=C([H])N(C1=O)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C1=C(C#N)[C@]([H])(C2=C(N([H])N=C2O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N1C(=O)N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])C(=O)C([H])([H])OC1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=NN(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])N([H])[C@]([H])(C1=C([H])C(F)=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N2C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C(F)=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NN([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1=NC(=NC(=N1)N([H])C([H])([H])C#N)C([H])([H])[H]
[H]N(C1=C(C#CC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=NC(=N1)C#N)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])N1C(=NC2=C([H])C(=C([H])C([H])=C12)N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(OC([H])([H])C(=O)O[H])C(Br)=C(S1)C1=C([H])C(N([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C([H])=C(Cl)C([H])=C(Cl)C2=N1)C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C(C([H])=C(OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H]
O=C1CCCN1CCCNCC1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C(C#N)C(=N1)N([H])[H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])[H]
[H]S\C(=N\C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C([H])=C(OC([H])([H])[H])C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1Cl
[H]N(C1=NC(N([H])C([H])([H])[H])=C(C([H])=N1)C(F)(F)F)C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1OC([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NC2=C(S1)N=C([H])N=C2N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=NC([H])=C([H])C([H])=C1C(F)(F)F
[H]C1=NN(C([H])=C1C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C1=C([H])C(=C([H])C([H])=C1SC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])OC2=C([H])C([H])=C([H])C([H])=C2C1=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C(=O)O[H]
[H]N1C([H])=C(C(=O)C(=O)N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(C(=O)N3C([H])([H])C([H])([H])C([H])(C([H])([H])C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]N(C1=NC(=C(S1)C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)N1C2=C([H])C(Cl)=C(C([H])=C2C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C([H])C([H])=C(S1)C1=C(C2=C(N1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])N(C2=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(N([H])[H])=C(C([H])=C1C([H])([H])[H])S(=O)(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(N1C(SC([H])([H])C(=O)OC([H])([H])[H])=NN=C1C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C([H])([H])Cl)C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C(=O)C2=C(N=C1C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1O2)C(F)(F)F
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])=C([H])C([H])=C([H])[C@]12[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])N(N=C1[H])C([H])([H])C1=NOC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C(=O)C1=C(Cl)N=C(N1C([H])([H])C1=C([H])C([H])=C2N=C(OC2=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([O-])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C([H])([H])C1=C([H])C(O[H])=C(O[H])C(O[H])=C1[H]
[H]OC([H])([H])[C@@]([H])(N([H])C1=NC([H])=NC2=C1C1=C(S2)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])=C([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(=C([H])S1)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])[C@]2([H])C([H])([H])N(C(=O)[C@@]3([H])C([H])([H])[C@]3([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]12[H]
[H]OC1=C(C([H])=C([H])C([H])=C1N([H])C1=C(N([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C(=O)C1=O)C(=O)N(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1[H]
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[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(S2)C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C2SC(=C3[H])C2=C([H])N(C([H])=N2)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(F)=C1[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H]
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[H]N1C([H])=C([H])C2=C(C([H])=C([H])N=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
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CN1CCN(CC1)C1CC2=C(SC3=C1C=C(C=C3)C1=CC=NC=C1)C=CC=C2
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(N1C([H])([H])[H])C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])S(=O)(=O)C1=NC([H])=C(C([H])=C1[H])C(F)(F)F
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ON(=O)OCCNCCNC1=C2CCCCC2=NC2=CC=CC=C12
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[H]OC(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])[C@]([H])(OC(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C1=NC(=NO1)C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1=C2OC(=NC2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C(=C1[H])N1C([H])=NC(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2F)=C(C1=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=C(C([H])=C(Cl)C([H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]OC1=C(Cl)C([H])=C(C([H])=C1Cl)C1(OC(=O)C2=C([H])C([H])=C([H])C3=C2C1=C([H])C([H])=C3[H])C1=C([H])C(Cl)=C(O[H])C(Cl)=C1[H]
[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(O[C@@]2([H])C([H])([H])[C@@]([H])(OC(=O)N([H])C3=C([H])C(=C(F)C([H])=C3[H])C([H])([H])[H])[C@]([H])(C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])[C@]2([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(N([H])C(=N[H])N([H])[H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])[H])[C@@]1([H])N([H])[H])N1C([H])=NC2=C(N=C([H])N=C12)N([H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=NN([H])C2=NN=C(C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(O[H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C([H])=O)C([H])([H])C(=O)O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=NC2=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])S(=O)(=O)C3=C([H])C4=C(OC5=C4C([H])=C([H])C([H])=C5[H])C([H])=C3[H])C([H])=C([H])C([H])=C2N1[H]
[H][C@]12CC[C@]([H])(C[C@H](C1)OC1=CC=CC(=C1)C(N)=O)N2CC1=CC=CC=N1
[H]OC1=C(N([H])C2=NS(=O)(=O)N=C2N([H])[C@@]([H])(C2=C([H])C([H])=C(O2)C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)[C@@]1(C2=C([H])C([H])=C(C([H])=N2)C([H])([H])[H])C([H])([H])C2([H])N(C([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C(Cl)C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1F)N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C1=NN([H])N=N1
[H]SC1=NC(=NN1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C(OC1=C([H])C([H])=C(C([H])=N1)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@](C1=C([H])C(Br)=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NN(N=C1[H])C1=NC(=C([H])C([H])=C1C(=O)N1C([H])([H])[C@]([H])(OC2=NC([H])=C([H])C(C#N)=C2[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C(F)(F)F
[H]C#CC([H])([H])N1C(=O)C2=C(SC3=C2C([H])([H])C([H])([H])C3([H])[H])N=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=NSN=C12)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(=C([H])C2=C1N=C(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])N=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]\C(=C(\[H])[C@@]1([H])N(C(=O)[C@@]1([H])N1C(=O)OC([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C(F)(F)F)=NC([H])=C1[H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
OC1=C(C=C(\C=C2/C(=O)NN(C2=O)C2=CC=C(Cl)C(Cl)=C2)C=C1)N(O)=O
[H]C1=C([H])C([H])=C(C([H])=N1)[C@]([H])(C#N)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2N=C(C3=C([H])C([H])=C(SC([H])([H])[H])C([H])=C3[H])C3=C(C([H])=C([H])C([H])=C3[H])C2=O)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C(O[H])(C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(C([H])([H])C1=C([H])C(=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])O2)C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(N=C(C([H])=N2)N2C([H])([H])C([H])([H])C3(C(=O)N(C([H])([H])C4=C5C(=C([H])C([H])=C4[H])N(C([H])([H])[H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C2=C(N=C(N=C2C([H])=C1[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
NC1=NNC(=O)C2=C1C=CC=C2
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C(C#CC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1OC1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N(N([H])C1=C(C([H])=C(C([H])=C1[H])[N+]([O-])=O)[N+]([O-])=O)C(\[H])=C1\C(=O)N(N=C1C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C(\C(=C(/[H])C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C12)C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[C@@]2([H])SC2([H])[H])=C([H])C([H])=C1F
[H]N(C1=NN=C(C([H])=C1C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C2=NC(=NC(=C2C([H])([H])C([H])=C([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])\N=C(/N([H])C#N)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])\N=C(/N([H])C#N)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]\C(=C(\[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=N1)N(C([H])([H])[H])C([H])([H])[H])C1=NC(=C([H])C(=N1)N1C([H])([H])C2=NC([H])=C([H])N2C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])C1=NC(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NC2=C1N([H])C(=O)N2[H])C([H])([H])[H]
[H]C1=NC2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C(=N1)N1C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C([H])=C3C([H])=C([H])C([H])=NC3=C2[H])C1([H])[H]
[H]N(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2C(C2=C([H])C([H])=C([H])C([H])=C2F)=C1C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C(=C([H])C(=N1)C([H])([H])SC1=NC(=C(S1)C([H])([H])F)C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])N=C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C3([H])[H])C([H])=C1[H]
[H]N(\C(=N\S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(OC(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)S(=O)(=O)C1=C2N=C3C(=C([H])N2N=C1SC([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H]
[H]N(C1=NC([H])=C(C#CC([H])([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C(=O)N(C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C(Cl)C([H])=C1Cl)C1=NC(=C(N=C1C([H])([H])C([H])([H])[H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C(Br)=C(Br)S1
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])N1[H]
[H]N(C1=NN([H])C2=C1C(=NC([H])=N2)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OC([H])([H])C([H])([H])C(=O)N([H])[C@@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C(OC2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)=C([H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])N(C(=O)C11C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(Cl)C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(C2=NC(N([H])[H])=C(C#N)C(=C2[H])[C@]2([H])C([H])([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]1([H])C([H])([H])[H])C(=O)OC1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=C(N=C2C([H])=C([H])C([H])=C([H])N12)C1=C([H])C([H])=C([H])C(=C1[H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H][C@@]12OC3=C4C(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]51CC[C@@]2(OC)[C@]([H])(C1)[C@](C)(O)C(C)C)=CC=C3O
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[C@@]11C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NN([H])N=N1
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[H]N([H])C1=C2N=C(N=C2N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H])C(OC([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C2=C(C([H])=C(C(Cl)=C2[H])S(=O)(=O)N([H])[H])S(=O)(=O)N1[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=C(N=C(S1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]C1=C(OC(=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)O[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C3=C(N=C2[H])N=C(N=C3N([H])[H])N([H])[H])C([H])=C1[H])C(=O)O[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C(=NN1[H])C1=C(Cl)C([H])=C(Cl)C(F)=C1[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C(OC([H])([H])[H])=C(N([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC2=C(N=C([H])N=C12)C1=C(N=C(N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(C([H])=C(S2)C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2O[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])N1N=C(C2=C1C([H])([H])C([H])([H])N([H])C2([H])[H])C1=C([H])C(SC([H])([H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])N=C(O1)C1=C(C([H])=C(F)C([H])=C1[H])[C@@]1([H])C([H])([H])N2C([H])=C([H])N=C2C1([H])[H]
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(P(=O)(O[H])O[H])P(=O)(O[H])O[H]
[H]O[C@@](C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2(C3=C([H])C([H])=NC([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C([H])([H])[H])(C([H])([H])[H])C(F)(F)F
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NOC(=N2)C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C(=O)C3=NC4=C(C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])C2([H])[H])=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
NC1(CCC1)C1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=C(C=C1)C1=CC=CC=C1
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N2C(=NC3=C([H])N=C4N([H])C([H])=C([H])C4=C23)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])[C@]([H])(C([H])([H])C(=O)OC([H])([H])[H])[C@]([H])(C(=O)N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]C1=NC([H])=C(C([H])=C1C1=C([H])C2=C3N(C(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C3=C1[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]O[C@@]([H])(C([H])([H])N1N=C(C2=C1C([H])([H])C([H])([H])N([H])C2([H])[H])C1=C([H])C(SC([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC1=NN=C(N1C([H])([H])[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2O1)C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=NSC(=N1)C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2=O)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C3=C([H])C(Cl)=C(Cl)C([H])=C3C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(=C(S1)C1=C([H])C([H])=C(C(=C1[H])C(F)(F)F)S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C(OC3=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC4=C(C([H])=C(C(O[H])=C4[H])C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])C([H])([H])[H])=C3C([H])([H])C([H])([H])C(=O)O[H])C2=O)C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1N([H])C(=O)C([H])([H])[C@@]1([H])N2C(=O)C(=O)N([H])C3=C([H])C(Cl)=C([H])C(=C23)C([H])([H])C1([H])[H])C([H])([H])N([H])[H]
[H]N([C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])C1=NN2C(=NN=C2C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(N=C1[H])N([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])C2([H])[H]
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[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C([H])C(Cl)=C(OC([H])([H])[H])C(Cl)=C2[H])C([H])([H])C2(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])N(N=C1C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C(C([H])=C3N3C([H])=NC([H])=C23)N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H]
[H]OC(C1=C([H])C(Cl)=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]OC([H])([H])C1=C([H])N(N=C1[H])C1=NC2=C(N=C([H])N2[C@]2([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]2([H])O[H])C(=N1)N([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C1=C(C(=O)N([H])C1=O)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=C(S1)C1=C([H])SC(=N1)N([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])=C(C(=O)N1C1=C([H])C(=NC([H])=N1)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(C#N)=C([H])N=C1[H]
[H]C1=NC2=C(C([H])=C([H])C([H])=C2N1C1=NC([H])=NC([H])=C1[H])C1=C(C([H])=C([H])N=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C(N=C(SC([H])([H])[H])N=C1SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])C([H])([H])C([H])([H])C([H])([H])[H]
CC(C)(C)C1=CC=C(NC(=O)N2CCC3=C(C2)NC2=C3C=CC=C2)C=C1
[H]N(C(=O)C(\[H])=C(/[H])[C@@]([H])(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]C1=C(N=C2C([H])=C([H])C([H])=C([H])N12)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(Cl)=C3Cl)C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N1C(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N([H])[C@@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=C(C3=C(N=C([H])N=C23)N([H])[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2O1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])([H])[C@@]3([H])C([H])([H])[C@]2([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
CC1=CC=C(C)C(=C1)C(=O)CCCN1CCC(O)(CC1)C1=CC=C(Cl)C=C1
[H]O[C@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C(=C2[H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])[C@]1(OC([H])([H])[H])C([H])([H])N(C2=NN=C(S2)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N(C1=C(Cl)C(=C(Cl)C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])N2C(Br)=C(N=C12)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(C(=O)OC([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(I)C([H])=C1[H])C2([H])[H]
[H]C([H])([H])C1(C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C(=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C([H])C(OC2=C([H])N=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]\C(=C(\[H])C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])[C@@]23C([H])([H])C([H])([H])[C@]1(OC([H])([H])[H])[C@]1([H])OC4=C(OC([H])([H])[H])C([H])=C([H])C5=C4[C@]21C([H])([H])C([H])([H])N(C([H])([H])C1([H])C([H])([H])C1([H])[H])[C@]3([H])C5([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(=O)N([H])C1=C(C(=O)O[H])C2=C(S1)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])OC([H])([H])[H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(C([H])=NC2=C(C([H])=NN12)C1=C([H])N(N=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N(C([H])([H])C([H])([H])N1C(=O)N(C3=C([H])C(OC(F)(F)F)=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C2([H])[H]
[H]C1=C(SC(=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C([H])=N1)C([H])([H])[C@]1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[C@@]1([H])[18F]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C(F)C(F)=C(F)C(F)=C1F
[H]C1=C([H])C2=C(C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C1=C2ON=C1C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C(=O)C(=O)N1[C@@]2([H])C(=O)N3C([H])([H])C([H])([H])C4=C(C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C4[H])[C@]3([H])[C@]1([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C(=O)N([H])C1=NC([H])=C(S1)C([H])([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C([H])C([H])=C1[H])S(=O)(=O)C1=NC([H])=C([H])C([H])=C1[H]
CCNC1=NC(C(N)=O)=C2CN(CCC2=N1)C(=O)CCC1=CC=C(CC(F)(F)F)C=C1
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]2(C([H])=C(C(=O)N([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N(C1=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@]13C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC4=C([H])C([H])=C([H])C([H])=C4[H])[C@]([H])(C2([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(\C([H])=C3/SC(=S)N(C3=O)C3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=NC(=C1[H])C1=NN2C(=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=NC2=C(O[H])C([H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]OC(=O)C(\[H])=C(/[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C(OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C(N=C1[H])C([H])([H])[H]
COC1=CC=C2N(C(=O)C3=CC=C(Cl)C=C3)C(CC(C)C(=O)NS(C)(=O)=O)=C(C)C2=C1
[H]N(C1=C2C([H])=C([H])C([H])=C([H])C2=C(N=N1)C1=C([H])C([H])=C([H])C2=C([H])N=C([H])C([H])=C12)C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2F)C(=N1)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N1C(=NC2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H]
[H]N1C2=C(N=C1[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
CC1=CC=C(C(C)=C1)S(=O)(=O)N1CCC(CC1)C(=O)NC1=CC=C(C=C1)C(O)=O
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(OC([H])([H])C([H])([H])O[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(N([H])C([H])([H])[H])=C(Cl)C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C(N([H])C2=C3C([H])=NN(C3=NC([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N=C(N([H])[H])N([H])C(=O)[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]([H])(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C(F)=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])S1)[C@@]([H])(O[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N2C(=NC(=C(C2=O)C2=C([H])C([H])=C(C#N)C([H])=C2[H])[C@]([H])(N(C(=O)C([H])([H])C2=C([H])C(=C(F)C([H])=C2[H])C(F)(F)F)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])\C(=N\C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])\N=C1/N3C(=NC4=C1C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])N1C(=N2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C2=C(OC([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C1=NC([H])=C([H])C([H])=C1[H])[C@@]1([H])[C@@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])SC1=NC(=O)N([H])C(=C1C(=O)OC([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C(S1)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
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COC(=O)C(N1C(C2=CC=C(Cl)C=C2)C(=S)NC2=CC=C(F)C=C2C1=O)C1=CC=C(Cl)C=C1
[H]O[C@@](C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C(F)(F)F
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[H]N1C2=C(C([H])=C(OC(=O)C([H])([H])N3C(=O)C4=C([H])C([H])=C([H])C5=C4C(=C([H])C([H])=C5[H])C3=O)C([H])=C2[H])C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])\C(=N/OC([H])([H])C([H])([H])[H])C2=C(N([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])=C(F)C(=C2F)C1=C([H])C([H])=C([H])C2=C1N([H])C([H])=C2C([H])([H])[H]
[H]OC1=C2C([H])=C(N(C2=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=N[H])N([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
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[H]N1C(=O)N([H])C(=O)C2(N(C(=O)C([H])([H])C2([H])[H])C2=C([H])C([H])=C(OC3=C([H])C([H])=C(C([H])=C3[H])C(=O)OC([H])([H])[H])C([H])=C2[H])C1=O
[H]C1=C([H])N(C([H])=N1)[C@@]([H])(C1=C([H])N(C2=C1C([H])=C(Br)C([H])=C2[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C(=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])[C@]1(N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C1=[N+](C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]N(\N=C(/[H])\C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C(=O)C1=C([H])C([H])=C([H])S1
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(F)=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C([H])C(=C([H])C(=C2O[C@@]1([H])C(F)(F)F)C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C2=C1OC(=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2C(F)(F)F)C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C(OC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C2=C(N=C(C([H])=C2C([H])([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C2C([H])=C([H])C(=NC2=NC([H])=C1C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=O)C(SC([H])([H])C([H])([H])[H])=C([H])C(=O)C2=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C3=C(C([H])=C12)N(C(=O)O3)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C2=NC([H])=C([H])C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C(=C2[H])C([H])([H])[H]
[H]O\C(OC([H])([H])[H])=C1\C(=NC(=C(C(=O)OC([H])([H])C([H])([H])SC2=C([H])C([H])=C([H])C([H])=C2[H])[C@]1([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)N([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]N1C(=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])C([H])([H])N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])[C@]([H])(N2C(=NC4=C2C([H])=C([H])C([H])=C4[H])C([H])([H])[H])C3([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C(F)=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)C([H])([H])C([H])([H])[H])C1=NC([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=NC2=C1C(=C(O2)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(Cl)C([H])=C2C(=N[C@]([H])(C1=O)C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C(N=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2C2=NN(C([H])=C12)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C(C2=C([H])N=C(C([H])=C2[H])N2C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C2([H])[H])C(=O)C2=C([H])C([H])=C(C([H])=C2O1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(N([H])C(=O)C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])[H])C([S-])=S
[H]O[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NN(C3=C([H])C([H])=C([H])C([H])=C13)C([H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]N1C([H])([H])C2=C([H])N=C([H])N2C([H])([H])C2=C([H])C(OC3=C([H])C4=C(C([H])=C([H])C([H])=C4C([H])=C3[H])N(C(=O)C1([H])[H])C([H])([H])[H])=C(C#N)C([H])=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1(C(=NN(C2=C([H])C(F)=C([H])C([H])=C2F)C1([H])[H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C1=C([H])C([H])=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2N([H])C([H])=C([H])C2=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C2C([H])=C(OC([H])([H])[H])C(C#CC3=NC(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])C2=NC([H])=C1C#N
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])C(=O)C1=C(F)C([H])=C(F)C([H])=C1F)C([H])([H])OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C1(N2C([H])([H])C([H])([H])C([H])(N3C(=NC4=C3C([H])=C([H])C([H])=C4[H])N3C([H])([H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N([H])S(=O)(=O)N([H])C([H])([H])[C@]12OC(O[C@@]1([H])[C@]1([H])OC(O[C@]1([H])C([H])([H])O2)(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])=C(C2=C([H])C([H])=C3N([H])C([H])=C(C3=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C(=S)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC([H])=NC2=C1C([H])=C(S2)C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@](C(=O)N([H])C([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(N=C2[H])N2C([H])([H])C([H])([H])N([H])[C@@]([H])(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NN=C([H])N1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(Br)=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C(=O)C1=C([H])C([H])=C([H])C(C#N)=C1[H])[C@]([H])(C1=NC2=C(C(=C([H])S2)C([H])([H])[H])C(=O)O1)C([H])([H])[H]
[H]SC1=NN=C(S1)N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N(C1=C2C([H])=C([H])C(N([H])C([H])([H])C([H])([H])[H])=C([H])C2=NC([H])=N1)C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]C1=C([H])C([H])=C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C3(C([H])([H])C([H])([H])N(C(=O)C4=C([H])C([H])=[N+]([O-])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C3=C(N([H])C([H])=C3C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C([H])([H])SC2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])[N+]([O-])=O
[H]N(C1=NC([H])=C2N=C([H])N=C(N([H])C3([H])C([H])([H])C4=C(C([H])=C([H])C([H])=C4[H])C3([H])[H])C2=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
CCCCN1C2=NC3=C(N2C=C1C1=CC=CC=C1C)C(=O)NC(=O)N3C
[H]N(C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C2=C([H])C([H])=C([H])N=C12)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1N=C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC([H])([H])[C@@]1([H])C2=C([H])C([H])=C([H])C3=C2N(C2=C3C3=C(C(=O)N([H])C3=O)C3=C2N([H])C2=C3C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C(=O)N(C1=C(Cl)C(=C(Cl)C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])N2C(Br)=C(N=C12)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C3=C(N([H])C([H])=C3C([H])([H])C([H])([H])N([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)N2C([H])=NN=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)C1=NN2C([H])=NC3=C(SC(=S)N3C3=C([H])C(Cl)=C([H])C([H])=C3[H])C2=N1
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C#N)C1=C(N=C([H])C([H])=C1[H])C([H])([H])[H])C([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NOC([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]1([H])OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=NC(=C([H])S1)C1=C([H])C2=C(N([H])C3=C4C(=C5C(=O)N([H])C(=O)C5=C23)C([H])([H])C([H])([H])C4([H])[H])C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C(=O)N([H])[C@]([H])(C1=C([H])C(F)=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N2C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=NN1C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C1([H])O[C@@]([H])(C2=C(OC([H])([H])[H])C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(N=C(C(=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])N([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]SC([H])([H])[C@@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])S([O-])(=O)=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(OC(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]C1=C([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C(C(=O)N3C([H])([H])C([H])([H])N(C4=C([H])C(=C([H])C([H])=C4[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])=C2C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C1=C([H])C(Br)=C([H])C([H])=C1N([H])C(=O)C2([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C1=NC(=NO1)C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(S[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(O[C@]([H])(N2C(=O)C([H])([H])C([H])([H])[H])C2=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C(Br)=C2[H])N=C(SC([H])([H])[H])N=N1
[H]N(C(=O)C1=C([H])C([H])=C(\N=N\C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])[C@]([H])(C(=O)C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[N+]([O-])=O)S(=O)(=O)C([H])([H])[H]
[H]O[C@@](C([H])([H])N1C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])(C([H])([H])C(C1=C(OC([H])([H])[H])C([H])=C([H])C(F)=C1[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])OC([H])([H])C1=C(C([H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C(N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C#N)C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)[C@@]([H])(N1C(=O)[C@@]([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])S(=O)(=O)N1C([H])([H])[C@@]2([H])C(=O)N(C3=C([H])C([H])=C(OC(F)(F)F)C([H])=C3[H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(C#C[C@]([H])(O[H])[C@]2([H])N(C(=O)C([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])=C1[H]
[H]N1N=C(C2=C([H])SC(C#CC([H])([H])OC3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])C2=C1C1=C([H])C([H])=C(C([H])=C1C2([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C#CC([H])([H])[H])C(=O)[C@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])[H]
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2O\C1=C(\[H])C1=C(F)C([H])=C([H])C(F)=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])N1C2=C(C([H])=C(Br)C([H])=C2[H])C([H])([H])N(C(=O)C([H])([H])[H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C3=C2C([H])=C([H])C([H])=C3[H])C1([H])[H]
[H]N1C2=C(C(=NN2C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(S[C@]([H])(C1=O)C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(N=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])[C@]([H])(OC2=NC([H])=C([H])C(C#N)=C2[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C(\[H])=C(/[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C(F)=C([H])C([H])=C2[C@@]([H])(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]