[H]C1=C([H])C(Br)=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])O[C@]1([H])C([H])([H])N2C(=O)N(C(=O)[C@]2([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]C1=C([H])N(C([H])=N1)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=NC2=C([H])C(=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C2N(N=C1C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N(C(=O)C([H])([H])[C@]2([H])ON=C(C3=C([H])C([H])=C(C([H])=C3[H])C(=N[H])N([H])[H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])[C@@]2(C(=O)OC([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NC([H])=C(S1)C1=C([H])C([H])=C2C([H])=NC([H])=NC2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])N(C3=C2C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])C(O[H])=C(C(=O)N([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(N([H])C2=C3C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C3=NC3=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C([H])=C23)C([H])=C1[H]
[H]N([H])C1=C(C([H])=C2N=C(N=NC2=C1[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]([H])(N([H])C(=O)OC([H])([H])[H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])N=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C2=C1N([H])C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=NN([H])C3=C2C(=NC([H])=N3)N([H])C2=C([H])C([H])=C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]([H])(SC1=NN=C(O1)C1=C([H])C([H])=C([H])O1)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C(N([H])S(=O)(=O)C(F)(F)F)C([H])=C([H])N=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C(C2=C([H])C([H])=C([H])C([H])=C2S1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(OC([H])([H])[C@@]2([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C3=C(C([H])=C2[H])N(C(=O)C3=C(C#N)C#N)C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])F)C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C(=C(N([H])C2=C([H])N=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])=C1[H])C([H])([H])[H])C([H])=O
[H]C1=C([H])C2=NC([H])=C(N=C2C([H])=C1[H])N1C([H])([H])C([H])([H])C2(C(=O)N(C([H])([H])C3=C([H])C(=C([H])C([H])=C3[H])C3=NOC(=N3)C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C2=C(OC([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])\C2=C(\[H])C([H])([H])N2C([H])=NC3=C2C([H])=C(OC([H])([H])[H])C([H])=C3OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC1=NC(=C(N1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C([H])C(=C3O2)S(=O)(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=NN(C(=O)C(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C([H])C(F)=C1F
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]C1=C([H])C([H])=C(O1)C([H])([H])N1C2=C(N(C(=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(=O)N(C1=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])[C@]2([H])C([H])([H])[C@]2(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C2=C1N1C(=N2)C([H])([H])[C@]([H])(C2=C(F)C([H])=C(F)C(F)=C2[H])[C@@]([H])([N+]([H])([H])[H])C1([H])[H])C(F)(F)F
[H]C1=NN2C(=C1Cl)C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])[H])[C@@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(OC2=C([H])C(=C(C#N)C([H])=C2[H])C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])C1=NC(=C([H])S1)C1=C(N([H])C([H])=C1[H])C([H])([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC([H])=NN2C([H])=C([H])C(C(=O)N([H])C3=C([H])C(=C([H])C([H])=C3[H])C([H])([H])N([H])C(=O)N([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])=C12
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C(N([H])C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C2=NC([H])=NC(N([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=N3)=C2[H])=C1[H])C([H])([H])[H]
COC(=O)C1=CN(N=N1)C1=CC=C2OS(=O)(=O)C=CC2=C1
CC1=NC(=C(S1)C(=O)CC1=CC=CC(=C1)[C@]1(C)CCSC(N)=N1)C(F)(F)F
[H]C1=C([H])C(=C([H])C(=C1OC([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C2C(=O)C([H])([H])C([H])([H])C([H])([H])C2=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(N=C(N([H])C2=O)C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])SC2=C1C([H])=C([H])C([H])=C2[H]
COC(=O)C1=C(CC2CCC1N2CCC[N+]12CCS[Re]11(=O)SCCN1C(=O)C2)C1=CC(Cl)=C(Cl)C=C1
[H]C1=NC(=C(O1)C1=C([H])N2C(=NN=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=C(F)C([H])=C([H])C(F)=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(OC3=NC([H])=NC(=C3[H])C3=C(N=C(C([H])=C3[H])C(F)(F)F)N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2S1
[H]OC(C1=C([H])C([H])=C2C([H])=C(N([H])C2=C1[H])C1=NN([H])C2=C1SC(=C2[H])C([H])(F)F)(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C(Cl)C([H])=C(Cl)C(=C1[H])N1C2=NC(=NC3=C2[C@]([H])(C1([H])[H])C([H])([H])C([H])([H])N3C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@](N([H])[H])(C([H])([H])[H])[C@@]([H])(O[H])N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C1=C([H])N=C(S1)N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])(C(F)(F)F)C(F)(F)F
[H]N(C1=C([H])C([H])=C(C#CC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)OC([H])([H])[H])C1([H])[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)C1=C([H])C([H])=C2O[C@@]([H])(C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])OC2=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)N([H])C(=O)C(N2C([H])([H])C([H])([H])N(C(=O)C3=C(C4=C([H])C([H])=C([H])C([H])=C4O3)C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])(C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(\C([H])=C(/[H])C2=C(Cl)C([H])=C(OC([H])([H])C3=C(ON=C3C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])=C1[H]
[H]OC([H])([H])C1=C([H])C2=C(S1)C([H])=NC([H])=C2SC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C(=C1[H])C1=NN=NN1C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C([H])=C([H])[C@]([H])(N1C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])[H])[C@]1(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]([H])(C2([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C([H])=NC3=C(C4=C(S3)C([H])([H])N(C([H])([H])[H])C([H])([H])C4([H])[H])C2=O)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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FC1=CC(=CC(=C1)C#CC1=NC(=CC=C1)C#N)C#N
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[H]N(\N=C(/[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C([H])C([H])=N1
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[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])O[C@]1(C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C1=NOC(=C1Br)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H]
OCC1=C(O)C=CC(OCC(O)CNC2CCN(CC2)C2=NC=NC3=C2C(=CS3)C2=CC=CC=C2)=C1
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COC1=CC(=CC=C1OCCCNC(=O)NC1=CC=C(C=C1)C(F)(F)F)C1=C(NC2CCCC2)N2C=C(C)C=CC2=N1
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[H]O[C@@]([H])(C([H])([H])OC1=C(C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
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[H]N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O\N=C1/C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C#N)N1C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(\C([H])=C2/C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])=C1[H]
[H]C([H])=C(C(=O)N([H])C1=C([H])C2=C(N=C([H])N=C2N([H])C2=C([H])C(Br)=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]ON([H])C(=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C(N=C([H])N=C2C([H])=C1[H])N([H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]OC1=C([H])C([H])=C2C3=C1OC1([H])C33C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])(C2([H])[H])C32C([H])=C([H])C1(OC([H])([H])C([H])([H])[H])C([H])(C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(OC([H])([H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N1C([H])=NC2=C([H])C3=C(C([H])=C12)N(C(=O)N(C3=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OS(=O)(=O)O[C@]([H])(C([H])([H])[C@@]1([H])C(=C([H])C([H])([H])[C@@]2([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])OC([H])=C1[H]
[H][C@]12CC[C@]([H])(C[C@H](C1)OC1=CC=CC(=C1)C(N)=O)N2C(C)C1=CC=NC=C1
[H]OC([H])([H])C1=C([H])C([H])=C(O1)C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(N([H])C2=C([H])C(=NC([H])=N2)N([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]SC([H])([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C(C#N)=C2[H])[C@@]1([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(C#N)=C([H])C(=C2O1)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(\[H])C2=C3\C(=N\N([H])C4=C([H])C([H])=C(C([H])=C4[H])S(=O)(=O)N([H])[H])\C(=O)N([H])C3=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1[H])[C@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])N=C2[H])C([H])([H])N(C([H])([H])[H])C1([H])[H]
[H]N1C(=O)N([H])C(=O)C(C1=O)(C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C(=C1C#N)C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(C(=O)C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=NC(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)C1=C([H])C([H])=C2N=C(C([H])=C([H])C2=C1[H])C([H])([H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])=C(C2=C([H])C(=C([H])C([H])=C12)N1C([H])=NN=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C(F)C(F)=C([H])C([H])=C1F)C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C(N=C(C(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H])C([H])([H])C1(N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=O)N([H])C(=O)N([H])C1=O
[H]N(C(=O)C1=C(N(C2=C([H])C(=C([H])C([H])=C12)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1=NC([H])=C([H])O1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1C(=O)N1C([H])([H])C([H])([H])N(C2=C(F)C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C2C(=C1[H])N(C(=C2C([H])([H])C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C(F)=C([H])C([H])=C1[H])C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C([H])C([H])=N1)C1=NC([H])=C([H])S1
[H]C1=C([H])C([H])=C(OC2=C([H])C([H])=C(F)C([H])=C2N(C(=O)C([H])([H])[H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])=C1[H]
[H]C([H])([H])C1=C2C(=[N+](N1C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2=O
[H]OC1=C([H])C(O[H])=C(Cl)C([H])=C1C1=NN([H])C(C(=O)N([H])C([H])([H])C([H])([H])[H])=C1C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC([H])([H])[H]
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[H]N1N=C(C2=C(N=NS2)C([H])([H])[H])\C(=C(/[H])C2=C([H])N(C3=C([H])C([H])=C([H])C(F)=C23)C([H])([H])[H])C1=O
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[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NN(C([H])=C1C1=C([H])C([H])=NC2=C1C(Br)=C([H])N2[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])N([C@]([H])(C4=C([H])C([H])=C(I)C([H])=C4[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C3([H])[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C1=NC2=C([H])C([H])=C(C([H])=C2C2=C1C(=O)N(C2=O)C([H])([H])C([H])([H])OC(=O)C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]1(O[H])C2=C(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])=C([H])C(Cl)=C2[H]
[H]N([H])C1=NC(=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C2C3=C(C([H])=C([H])C([H])=C13)C([H])([H])OC2([H])[H]
[H]OC1=C2O[C@@]3([H])C(=O)C([H])([H])C([H])([H])[C@]4(O[H])[C@@]3([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]4([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2O1
[H]C1=C(ON=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])\N=C1/OC([H])([H])C2(C([H])([H])N1C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
NC1CCC2=C(Br)C=CC(C3=CC=CC=C3)=C2CC1=O
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])=C1C([H])=C([H])C3=C([H])C([H])=C([H])C4=C([H])C([H])=C2C1=C34
[H]OC(=O)C([H])([H])[C@@]([H])(N1C(=O)C2=C([H])C(C#CC3=C([H])C([H])=C(C([H])=C3[H])C(=N[H])N([H])[H])=C([H])C([H])=C2N(C(=O)C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(C(=O)C2=C(O[H])C([H])=C(C([H])=C2O[H])C(=O)O[C@]2([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])[C@@]2([H])N([H])C(=O)C2=C([H])C([H])=C(O[H])C([H])=C2[H])C(O[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])C(\[H])=C(/[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])O1)C1=NC(=C(O1)C([H])([H])[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C([H])C([H])=C([H])C([H])=C4N=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C(N(C(=O)S1)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C(F)(F)F)C([H])([H])S(=O)(=O)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1(C#N)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)ON1C(=O)C([H])([H])C([H])([H])C1=O
[H]N1N=C(C2=C(C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=NC2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]([H])(N1C([H])=C([H])C([H])=C(C(=O)N([H])C([H])([H])C#CC2=C([H])C3=C([H])C(N([H])C4([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C4([H])[H])=C([H])N=C3C([H])=C2[H])C1=O)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C2=C([H])C(=C([H])C([H])=C2OC([H])([H])C([H])([H])[H])N2N=NN=C2C(F)(F)F)[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C([H])([H])[H]
Cc1cnc(Nc2cccc(c2)[N+]([O-])=O)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
[H]N1C(=O)S\C(=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
[H]N([C@@]([H])(C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C(=O)N([H])S1(=O)=O)S(=O)(=O)C1=C(Cl)C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(=C([H])C(C2=C([H])C([H])=C([H])O2)=C1C#N)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2N([H])C([H])=C(C2=NC([H])=N1)[C@]1([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]1([H])O[H]
[H]OC([H])([H])[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])OC([H])([H])C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(SC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])=NC(N([H])[H])=C1C([H])([H])C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=N/C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)OC([H])([H])[H])\N([H])[N+]([O-])=O
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C([H])([H])OC([H])([H])[H])C(=O)C1=NOC(=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C(=O)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C(=C([H])C([H])=C2Cl)C(F)(F)F)C1=O
[H]OC(=O)[C@]([H])(C1=C([H])C(N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C3=C2C([H])=C([H])C([H])=C3N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]OC(=O)C1=C(C(=C([H])C([H])=C1N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C(N([H])S(=O)(=O)C2=C(Cl)C(=C(Cl)C([H])=C2[H])C([H])([H])OC2=C3N=C(C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N([H])[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(N([H])C(=O)C1=C(F)C([H])=C(F)C([H])=C1F)C([H])([H])OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)C3=C(C([H])=C(C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C2=C([H])C3=C(C([H])=NN3C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])[C@]2(C([H])([H])[H])C1([H])[H]
[H]N(N([H])C1=C([H])C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])[N+]([O-])=O)S(=O)(=O)C([H])([H])[H]
[H]N(C1=NC2=C(S1)C([H])=C(C([H])=C2[H])C1=C([H])C([H])=NN1C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C2=NN=C(O2)C2=C([H])C(Cl)=C(OC([H])(C([H])([H])[H])C([H])([H])[H])N=C2[H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C2(C1([H])[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])=C1C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=O)C1=C(C(=O)OC([H])([H])C([H])([H])[H])C(=C(S1)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C2(N(C(=O)N(C2=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(C2=C3N=C(N=C(N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C(N=C1OC([H])([H])[H])C([H])([H])[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(C([O-])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]C1=NC(OC([H])([H])[H])=C2N=C(N(C(=O)C2=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C1=C2C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C(Br)C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)[C@]1([H])[C@@]([H])(O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C([H])([H])N2C(=O)C([H])=C(C3=C([H])C([H])([H])N(C([H])([H])C3([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]12[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N=C1[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])S2)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)O[H])C1=C([H])C(=C(O[H])C(=C1[H])C1=NC2=C(N1[H])C([H])=C([H])C(=C2[H])C(=N[H])N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])[C@]1([H])OC(=O)OC([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])[H])[C@@]([H])(N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2C([H])([H])[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])N([H])C(=O)C([H])([H])[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C2C(=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C2([H])[H]
[H]N(C(=O)N([H])C1=C(Cl)C([H])=C(OC2=C([H])C([H])=NC(=C2[H])C2=NC([H])=C(N2[H])C(F)(F)F)C([H])=C1[H])C1=C([H])C(=C(F)C([H])=C1[H])C(F)(F)F
[H]N(C1=NOC2=C(C3=C([H])C4=C(C([H])=C3[H])C(=NN=C4[H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C([H])C([H])=C12)C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])SC1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H]
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[H]N1C(=NC2=C1C(=O)N(C(=O)N2[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C(C(=C2N1C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(Cl)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C2=NC3=C(O2)C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C([H])([H])[C@]1([H])N(C2=NC3=C(S2)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])([H])C([H])([H])OC1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])C(=O)C2=NN(C3=C([H])C([H])=C([H])C([H])=C23)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C(\C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])[H])=C1/C([H])([H])[C@@]2([H])N(C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])[H])C(C1=NOC(=N1)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=NO[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C2=NC([H])=C([H])N2[H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])S(=O)(=O)C([H])([H])[C@]([H])(N([H])C1=O)C(=O)O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N(C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
[H]N([H])C(=O)[C@@]1([H])[C@]2([H])C([H])=C([H])[C@@]([H])(C2([H])[H])[C@@]1([H])N([H])C1=C(Cl)C([H])=NC(=N1)N([H])C1=C([H])C2=C(C([H])=C1OC([H])([H])[H])N(C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H]
CC(C)(C)C1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
[H]N1C([H])=C([H])N=C1[C@]1([H])C2=C(C(=C([H])C([H])=C2[H])C2=C([H])N(N=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N(C(=O)C([H])([H])[H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C(=O)N([H])C([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])[C@]2([H])O[C@]([H])(O[C@]12[H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C(OC2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(OC3=C([H])C([H])=C([H])C(F)=C3C([H])([H])[H])N(C3=C([H])C([H])=NC([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(N([H])C2=C([H])C([H])=C([H])C([H])=C12)=C([H])C(=O)C1=C([H])C([H])=C([H])S1
[H]OP(=O)(O[H])C(F)(F)C1=C(Br)C([H])=C2C([H])=C([H])C(=NC2=C1[H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=NC([H])=N1)N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])N([H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C(=O)N([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=C([H])C(Cl)=C(N=C2C(=C1[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])[H]
CC1=CC(OCCCC2=C(NC3=CC=CC(Cl)=C23)C(O)=O)=CC=C1Cl
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(N=C2[H])N2C([H])([H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(SN=C1C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)OC([H])([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(C2=NN=C(N2C([H])([H])[H])[C@]23C([H])([H])C([H])([H])[C@](C4=NC(=NO4)C4=C([H])C([H])=C(F)C([H])=C4[H])(C([H])([H])C2([H])[H])C([H])([H])C3([H])[H])=C(C([H])=C1[H])C(F)(F)F
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC(=C(Cl)C([H])=N1)C1=C([H])C([H])=C2N([H])C([H])=C([H])C2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])SSC(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(N([H])C1=O)C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C(C3=C([H])C([H])=C(SC([H])([H])C([H])([H])[H])C([H])=C3[H])=C2O[C@]1([H])C(F)(F)F
CCOC1=CC=C(C=C1)C1=NN=C(O1)SCCN1C(C)=NC=C1[N+]([O-])=O
[H]OC1=C2O[C@@]3([H])C4=C(C5=C(N4[H])[C@]4([H])OC6=C(O[H])C([H])=C([H])C7=C6[C@@]44C([H])([H])C([H])([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])[C@]([H])(C7([H])[H])[C@]4(O[H])C5([H])[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]\C(=C(\[H])[C@@]1([H])N(C([H])([H])[H])[C@@]([H])(C(\[H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(Cl)C([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]12[H]
[H]N(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2N(C(SC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C(=C3[H])[N+]([O-])=O)=NC2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(N([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NN=C(C2=C1C([H])=C(N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]C1=C(SC2=C1C(=NC([H])([H])C1=NN=C(N21)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C#CC([H])([H])N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C(=O)O[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=O
COC1=CC(\C=C2/CCC\C(=C/C3=CC=CC(Br)=C3)C2=O)=CC(OC)=C1
[H]N1C(=C(C2=C([H])C([H])=C([H])C(Cl)=C12)[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@@]1([H])F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])C([H])([H])C([H])([H])O[C@@]1([H])O[C@]([H])(C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C1([H])[H])C(=O)N2C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])N1C(SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])=NN=C1C1=C([H])C([H])=C([H])C([H])=N1
[H]N(\C([H])=C(/[H])C1=C([H])C([H])=NC([H])=C1[H])C(=O)C1=NC([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C(Cl)C(=C(Cl)C([H])=C2[H])C([H])([H])OC2=C3N=C(C([H])=C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=N4)C3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])[C@@]([H])(C1=NC(=NO1)C1=C([H])C([H])=C(C([H])=C1Cl)S(=O)(=O)C([H])([H])[H])[C@]([H])(N([H])[H])C(F)=C1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(N=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])SC(=N1)C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]C(=O)C1=C(OC2=C([H])C([H])=C([H])C([H])=C2O1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(Cl)=NC(=C1[H])C1=C([H])C2([H])N(C([H])([H])[H])C([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)[C@]1([H])[C@]2([H])[C@@]1([H])[C@]1([H])C([H])([H])[C@@]2([H])C([H])([H])[C@@]1([H])C1=C([H])C(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])=C(C#N)C([H])=C1[H]
[H]O[C@]1([H])[C@]([H])(O[H])[C@]([H])(O[C@@]1([H])N1C([H])=C([H])C(=O)N=C1SC([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[P@](=O)(O[H])OP(=O)(O[H])O[H]
[H]N([H])C1=C([H])C2=NC([H])=NC(N([H])C3=C([H])C([H])=C([H])C(I)=C3[H])=C2C([H])=C1[H]
[H]N([H])N([H])C(=O)C([H])([H])SC1=NC2=C(C(=C([H])S2)C2=C([H])C([H])=C([H])C([H])=C2F)C(=O)N1C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(C1=C([H])C(=O)N(C2=C1C([H])=NN2C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N([H])[C@]1([H])C2([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C2([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C2C([H])=C(OC([H])([H])[H])C(\C([H])=C(/[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C2=NC([H])=C1C#N
[H]OC(=O)C1=C([H])C([H])=C2C3=NN(C4=C([H])C([H])=C(C#N)C(Cl)=C4[H])[C@]([H])([C@@]3([H])OC([H])([H])C2=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NN(C2=C1[C@]1(O[C@@]([H])(OC([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])OC1=C([H])C([H])=C2O[C@]([H])(C3=C(C([H])=C([H])C4=C3C(=C([H])C(N4[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=C1OC([H])([H])[H])C([H])([H])C([H])=C([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C(=C2[H])S(=O)(=O)C1=C([H])C([H])=C2N(C3=C(C2=C1[H])[C@@]1([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C1([H])[H])C3([H])[H])C([H])([H])[H]
NS(=O)(=O)C1=CC=C(C=C1)[N+]1=CC2=COC3=CC=CC=C3C2O[Zn]11(Cl)(Cl)OC2C(=COC3=C2C=CC=C3)C=[N+]1C1=CC=C(C=C1)S(N)(=O)=O
[H]N1N=C([H])C2=C1C([H])=C([H])C1=C2C(=O)[C@@]2(C1=C(Br)C(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2O[H])C([H])([H])[C@@](N([H])[H])(C(=O)O[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N
[H]C1=C([H])C(C2=NC(=C3N2C2=C([H])C(F)=C([H])C(OC([H])(F)F)=C2N=C3C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=NC(=C([H])C(=C1[H])C([H])([H])[H])C(F)(F)C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]\C(=C1\S\C(=N/C([H])([H])[H])N(C1=O)C([H])([H])[H])C1=C(N(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]1([H])C(=C([H])C([H])([H])C1([H])[H])C(=O)N(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])\N=C(/N([H])[H])[N+]([O-])=O
[H]C1=NC([H])=C([H])C(=C1[H])C1=C([H])N=C2N=C(OC2=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(C(=O)N([H])[C@@]([H])(C1=NN=NN1C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C2=C([H])C([H])=NC(=N2)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]OC(=O)C([H])([H])C1(C([H])([H])S[C@@]([H])(C2=C([H])C(\C([H])=C(/[H])C3=NC4=C(C([H])=C3[H])C([H])([H])SC4([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])O[C@]([H])(C1([H])[H])[C@@]([H])(OC([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])[N+]([O-])=O)C1=C([H])C(I)=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])C2([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])C1=C(C3=C(C([H])=C([H])C([H])=C3[H])C(=O)N1[H])C2([H])[H]
[H]N([H])C1=C(C([H])=NC(=N1)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C([H])=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1N([H])C1=C2C2=C(C(=O)N(N([H])C(=O)N([H])[H])C2=O)C2=C1N(C1=C2C([H])=C([H])C([H])=C1O[H])[C@]1([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]O[C@@](C(=O)N([H])C1=C([H])C2=C(C([H])=C1[H])C(=O)OC2([H])[H])(C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OP(=O)(O[H])[C@@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])N1N=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C(C2=NC3=C(N2[H])C([H])=C([H])C(=C3[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2N=C(SC([H])([H])[H])N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(OC1=C(C([H])=C2N(C(=O)OC2=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C(F)C(F)=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(F)=C(C([H])=C1[H])C1=NC(=C(C(=O)SC([H])([H])C([H])([H])[H])C(=C1C(=O)OC([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C(=O)[C@@]2([H])N3C4=C(C([H])=C([H])C([H])=C4C2([H])[H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C4=C(OC([H])([H])C4([H])[H])C([H])=C2[H])C3=O)C([H])([H])C1([H])[H]
CCNC(=O)C1=CC(NS(=O)(=O)C2=CC(C)=C(Cl)C=C2Cl)=CC=C1OC1=CC(Cl)=CN=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C([H])C2=C1C([H])=C(C([H])=C2[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]12[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)S(C)(=O)=O)C(=N1)N1CCOC[C@@H]1C
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=NN([H])C(=C2C([H])([H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2[H])C(F)(F)F)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)C([H])([H])C(=O)N([H])C1=C([H])C(Br)=C(OC2=C([H])C(=C(O[H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(Br)=C1[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=N1)N=C(N(C2=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(C(F)=C1[H])C(F)(F)F)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C([H])([H])C1=NC2=C([H])C(Cl)=C(F)C([H])=C2N1[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@@]([H])(N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C(F)=C1[H]
[H]OC(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(\C([H])=N\N([H])C(=S)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1F)N1C([H])=NC2=C1C([H])=C([H])N=C2[H])C(F)(F)F
[H]ON1C2=C3C([H])=C([H])C([H])=C([H])C3=C(N=O)C2=NC2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])SC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])OC(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(Cl)N=C2N([H])[C@]1([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2O1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC(F)(F)OC3=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C#N)C1=C(C([H])=C(F)C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C(\[H])=C(/[H])C3=C([H])C([H])=C(C([H])=N3)C3=C([H])C([H])=C([H])C(F)=C3[H])[C@]3([H])[C@]([H])(OC(=O)[C@]3([H])C([H])([H])[C@]2([H])C1([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]C1=NC(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])N([C@]([H])(C4=C([H])C([H])=C(C([H])=C4[H])C(F)(F)F)C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=N1)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(Cl)=C(OC(=O)C2=C([H])C3=C([H])C(=C([H])C([H])=C3OC2=O)C([H])([H])Cl)C([H])=C1Cl
[H]N1[C@@]2([H])C3=C(N(C4=C([H])C([H])=C(C([H])=C34)S(=O)(=O)N3C([H])=C([H])C4=C3C([H])=C([H])C(=C4[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC(=C([H])C2=C1C([H])=C([H])C([H])=N2)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]C1=C([H])C(=C([H])C(=C1Cl)[N+]([O-])=O)S(=O)(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C(=C1[H])[N+]([O-])=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C1=NC(=NC(=N1)N([H])C([H])([H])[H])N([H])C([H])([H])[H])C1=C([H])C([H])=C(C2=C([H])N=C([H])O2)C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]N(C1=NC(=NC(=N1)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H])C([H])([H])C([H])([H])N1N=C([H])C(=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N(C(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C1=C([H])C(N([H])S(=O)(=O)C2=C(C([H])=C(Cl)C(=C2[H])C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]SC([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]1([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])S(=O)(=O)N(C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=S)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C(OC([H])([H])[H])C(=O)C2=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2O1
[H]O[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C#N)[C@]([H])(O[H])[C@]1([H])O[H]
[H]C1=NN=C(O1)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]