[H]C1=NC([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C2=C3C([H])=C([H])N=C(Cl)C3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1(C(=O)N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C2=NS(=O)(=O)C3=C([H])C(F)=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N=C(OC3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])SC2=C1[H]
[H]N([H])C1=NC([H])=C([H])C([H])=C1C1=NC2=C([H])C([H])=C(N=C2N1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
CCC1=CC=C(CC2=CC=CC=C2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)S1
[H]N(N([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])S(=O)(=O)C2=C([H])C([H])=C([H])S2)C([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C([H])S1
[H]O[C@]1([H])[C@]([H])(O[C@@]([H])(N2C([H])=NC3=C(N=C(Cl)N=C23)N([H])[C@@]2([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C3([H])[H])[C@@]1(O[H])C([H])([H])[H])C([H])([H])Cl
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C(Cl)C([H])=C([H])C(=C1[H])C1=NC([H])=C([H])N(C1=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N(C3=C2C([H])=C(Cl)C([H])=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])OC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])N(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])P(=O)(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2N2N=NN=C12)C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=S)N([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C([H])N=C12)N([H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]OP(=O)(O[H])C(F)(F)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@](N1N=NC2=C1C([H])=C([H])C([H])=C2[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C(Br)=C1[H])C(F)(F)P(=O)(O[H])O[H]
[H]OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C(C(=O)N([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])([H])C1([H])[H]
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C(C3=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C4=C([H])C([H])=C([H])C(F)=C4[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1Cl)C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])C2([H])[H])C([H])([H])N(C(=O)OC([H])([H])[H])[C@]1([H])C(=O)N1C([H])([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1[H])C([H])([H])OC1=C([H])C([H])=C2C(=O)C3=C(N=NC(=C3[H])C([H])([H])[H])C2=C1[H]
[H]O[C@]1([H])[C@]([H])(N([H])[H])C([H])([H])[C@]([H])(C2=C(C([H])=NC([H])=C2[H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C(=N2)C2=C(F)C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C(=C([H])C(=C1[H])C(=O)C([H])([H])[H])C(=O)C([H])([H])[H]
[H]N1C(=O)C([H])([H])OC2=C([H])C(F)=C(C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3C([H])=C([H])C(=NC3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])[C@]([H])(OC([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C#N)C(=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C(Cl)C([H])=C2[C@]([H])(O[H])C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]([H])(N([H])C1=C(C#N)C(N([H])[H])=C([H])C(=N1)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])N(C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1I)[C@@]([H])(C(=O)OC([H])([H])[H])[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C(N=[N+]=[N-])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N([H])C1=C([H])C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C(C([H])=C2N1C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C(=O)C1=C(F)C([H])=C([H])C([H])=C1Cl
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1(OC([H])([H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)[C@]3([H])[C@@]4([H])C([H])([H])C([H])([H])[C@]([H])(C4([H])[H])[C@]3([H])S2(=O)=O)C([H])([H])C1([H])[H])C(F)(F)F
[H]C1=NN(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C([H])C([H])=C([H])C([H])=C4N=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(N([H])C(=O)C(F)(F)C(=O)[C@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
CN1CCN(CCCNC(=O)C2=CC3=C(CCC4=C(C=CC(NC5=C(F)C=C(F)C=C5)=C4)C3=O)C=C2)CC1
COC1=CC=C(C=C1)C1=[N+]2C(C=C1)=CC1=C(C)C(CCC(=O)NCCCCCC(=O)NCCCN3N=C(C(=O)NC4C[C@@H]5CCC[C@@H](C4)N5C)C4=CC=CC=C34)=C(C)N1[B-]2(F)F
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C2=C1N=C(N2C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C2=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C3=C([H])C4=C(C([H])=C3[H])C([H])([H])C([H])=N4)[C@@]1([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1\C([H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])[C@@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(N([H])C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C2=NN(C([H])=C2[H])C2=C([H])C([H])=C(O[H])C([H])=N2)C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C(F)=C2F)C([H])([H])C1([H])[H]
[H]O\N=C(\C(=O)N([H])C([H])([H])C([H])([H])S[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N(N=C1C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(N=C([H])N=C2C([H])=C1OC([H])([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H]
[H]N(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(SC2=C(SC3=C2C(=O)N([H])C(=N3)N([H])[H])C([H])([H])[H])C([H])=C1[H])C(=O)O[H]
[H]N([H])C1=N[C@@](C2=C([H])C([H])=C([H])C(F)=C12)(C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=C([H])C(C#CC([H])([H])[H])=C1[H])C1=C([H])N(C(=O)C(=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C1C(=C([H])C(F)=C2F)C1=C([H])C(=C2N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]([H])(C2=C1Cl)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(=C(/[H])C([H])([H])[H])\C([H])([H])[H])[C@]1([H])C([H])=C2C([H])([H])C([H])([H])[C@@]3([H])C4=C([H])C([H])([H])[C@]([H])([C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(C([H])=C(S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C2=C1C([H])=C([H])C(=O)N2C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H]
[H]OC1=NC2=C(C([H])=C3C(N([H])[C@]4([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]34C([H])([H])[H])=C2[H])C(=C1[H])C(F)(F)F
[H]N([H])C1=C([H])C(OS(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=NC(SC([H])([H])C([H])([H])N([H])[H])=N1
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(N([H])[C@]2([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]OC(=O)C1=NN([H])C(=C1[H])N(C([H])([H])C1=C([H])SC([H])=C1[H])C([H])([H])C1=C([H])SC([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C([H])([H])SC1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@]1([H])C(=O)N(C(=O)C1([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C1=NN([H])N=N1
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(C([H])=C(C([H])=C1C([H])([H])[S@@](=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=N/C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])\N([H])[N+]([O-])=O
[H]OC(=O)C1=C(C(=NC2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C(C2=C(N=C1C([H])([H])[H])C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C2([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C1=C([H])C(=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C2N=C(C([H])=NC2=C1[H])N1C([H])([H])C([H])([H])C2(C(=O)N(C([H])([H])C3=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1=C([H])C([H])=C([H])N=C1C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])S(=O)(=O)C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])N([H])[C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])C(F)(F)F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1(C([H])([H])C([H])([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]\C(=C(\N1N=C([H])N=C1[H])C(=O)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(C1=C([H])C([H])=C(O1)C1=C([H])C(Cl)=C([H])C([H])=C1[H])=C1\N=C(OC1=O)C1=C([H])C([H])=C([H])S1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C([H])C1=O)C([H])([H])C(N([H])C(=O)C1=C([H])C([H])=C(Cl)S1)(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(=C2[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])N(C2=C1C([H])=C1C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC2=C(C3=C(S2)C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C(=O)N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]22[C@]3([H])N(C([H])([H])[H])[C@@]([H])(C4=C([H])C([H])=C([H])C([H])=C4[H])[C@]4(C([H])([H])[H])C([H])([H])[C@]12C([H])=C([H])[C@]34OC([H])([H])[H]
[H]N1N=C(N(C1=S)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(N=C2[H])N2C([H])([H])C3=NC([H])=C(N3C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(O[C@]2(C1=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=CC=CC=C1C1=CC=C(O[C@@H](CC2=CC=CC=C2)C(O)=O)C=C1
[H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])[C@]1([H])C(=O)C([H])=C(OC([H])([H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
NC1=NC2=C(S1)C=C1CCN(CCO)CCC1=C2
[H]C1=C2OC([H])([H])OC2=C([H])C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(F)=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]N1C([H])=NC2=C(C([H])=C(C([H])=C2[H])C2=C(C([H])=NN2C2=NC(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=O
[H]N(\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H])C1=C2C([H])=NN(C2=NC([H])=N1)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])[H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C([H])C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N(\C([H])=C1/C(=O)C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)N1C(=S)N([H])N=C1C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N(C1=NC([H])([H])C([H])([H])N([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N2N=NC(=N2)C2=C([H])C(=NC(=C2[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=O)O2)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C(C(=O)N([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1Cl
[H]OC(=O)C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@](C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1Cl)N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C(F)(F)F
[H]N(C(=O)C1=NC(=C([H])C([H])=C1N([H])C1=C([H])N=C([H])N=C1[H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C(=NN1C([H])([H])[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=N1
[H]N(C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)O[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C(=C2[H])C2=C([H])C([H])=C(SC3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(OC3=C([H])C([H])=C(Cl)C([H])=C23)C(=N1)N1C([H])([H])[C@@]2([H])N([H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C(=O)N([H])C1=NN([H])C(=S)S1
[H]OC1=C([H])C([H])=C([H])C([H])=C1\C([H])=N\N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
ClC1=CC=C2OC(=NC2=C1)N1CCC(CC1)C(=O)N[C@H]1CCC[C@@H]1COC1=CC=CC=C1
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])[C@]12[H]
[H]O[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(S1)C([H])([H])N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])[C@@]([H])(O[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=NC([H])=C([H])S1
[H]N1C2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])C2=C1C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C2([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C2=C(N([H])[C@]([H])(C(=O)N(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N3C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C3=C([H])N([H])C([H])=N3)C2([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]OC(=O)C(OC1=C([H])C([H])=C(SC([H])([H])C([H])([H])C2=NC(=NS2)C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1(C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]3([H])C(=O)C([H])=C4[C@]5([H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@]5(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]4(C([H])([H])[H])[C@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]12[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1N=C([H])C2=C1C([H])=C([H])C(=C2[H])N1C([H])=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C1=O
[H]C1=NN(C2=NC([H])=NC(OC3([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1F)S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C2N([H])C(=O)C(C#N)=C(C2=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
O=C(NCCCN1CCCC1=O)C1=CN=C(NCCC2=CC=CC=N2)N=C1NC1=CC=CC=C1
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC(=NC(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C#N)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C2C([H])=C(N([H])C2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C1=C(N([H])C2=NC(=NC([H])=C2[H])N([H])C2=C([H])C(O[H])=C([H])C([H])=C2[H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(N1C(SC([H])([H])C#N)=NN=C1C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])[H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N(C1=O)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
CC(C)N(CC1=CN=CC=C1)C(=O)C1=C(OC2=CC=CC(Cl)=C2Cl)N(C)N=C1C
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2Br)C([H])=C1[H]
[H]N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(OC1=C([H])C(=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])O[C@@]1([H])[C@]([H])(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=NC([H])=C2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(N([H])S(=O)(=O)C4=C([H])C([H])=C([H])C([H])=C4Br)C([H])([H])C([H])([H])[C@@]3([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N([H])C([H])([H])C(\[H])=C(\F)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])C([H])([H])C1=C([H])C([H])=C(N=[N+]=[N-])C(I)=C1[H]
O=C(CN1C(=O)N2CCCC3=C2C1=CC(=C3)C1=CC=CC=C1)NC1=CC=CC=C1
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=NOC(=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])N2N=C(C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N1[C@]([H])(C#N)C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(C1=NC2=C(C([H])=C(F)C(=C2[H])C([H])([H])[H])N1[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])C3=C(C([H])=C(C#N)C([H])=C3[H])C2([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C3C([H])=C([H])OC3=C2C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C2=C(N=C(N2[H])C(=O)N([H])C([H])([H])[H])C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC(=O)ON1[H]
[H]N1C(=S)N([H])C2=C1C([H])=C([H])C([H])=C2C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3N=C(N([H])C3=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=O)C21C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C1(N([H])C(=O)C2=C([H])C(Br)=C([H])N=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C1=C(F)C([H])=C(C([H])=C1[H])N1N=C(Cl)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N(C(=O)N([H])S(=O)(=O)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C(C(=O)N([H])[C@@]([H])(C1=NN=C(N1C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(OC([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(O[C@]([H])(N3C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C(=C([H])C([H])=C4[H])C(=O)N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C([H])([H])O2)C([H])=C1[H]
[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N2C([H])([H])[C@@]([H])(C([H])([H])OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])([H])SC1=NC([H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])S(=O)(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C2C(=O)C([H])=C(C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)S(=O)(=O)C2=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N(C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C([H])([H])N1C([H])=C([H])\C(=N/C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C2=C1C([H])=C(Cl)C([H])=C2[H]
[H]N(\C(=N/C#N)N([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C(Cl)(Cl)C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1C([H])([H])[H]
[H]N(C(=O)C1=C2N(C([H])=C1[H])[C@@]([H])(SC2([H])[H])C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C(Br)C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=N[H])N([H])[H]
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C(F)=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C(=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])N([H])C(=O)C([H])([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C(=O)N(C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C2([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)N([H])C1=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2N=C1[H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]N([H])C(=O)C1=C(OC2=C([H])C(Cl)=C([H])C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2N=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=S)N([H])N([H])C2=C(F)C(F)=C(F)C(F)=C2F)C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(S1)C(=N[H])N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C1=NC([H])=C([H])C(=N1)C1=C([H])N([H])N=C1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C(C(=O)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C(=C(OC2=C([H])N=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C([H])C(O[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C12
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(N=C1[H])C([H])([H])[H])[C@]([H])(C1=NC2=C(SC([H])=C2[H])C(=O)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=NN1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C(F)S1)C1=C([H])C([H])=C(F)C(=C1[H])C(F)(F)F
[H]N([H])C(=S)N1N=C(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([C@]([H])(C([O-])=O)C([H])([H])C([H])([H])C([O-])=O)P([O-])(=O)OC([H])([H])C([H])([H])C([O-])=O
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=C([H])C(=C([H])C([H])=C2N1[H])C(=O)N([H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1Cl)C(=O)C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H]
[H]OC1=C(N([H])C2=C(N([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])C(=O)C2=O)C([H])=C(C#N)C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)[C@@]([H])(C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NC([H])=C([H])S1
[H]C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])O[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N1C(=O)C([H])([H])OC2=C1C([H])=C(C([H])=C2C([H])([H])[H])C1=C([H])C(=NN1C1=C([H])C([H])=C(F)C([H])=C1C([H])([H])[H])C(F)(F)F
[H]N(C(=O)C1=C(N=C(Cl)C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])(N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C2[H])C([H])([H])C2=C([H])N=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C(C2=NC(=NN2[H])C([H])([H])[H])C(=C([H])S1)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])OC3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])N(C(=O)N([H])C2=C([H])C(F)=C(C([H])=C2[H])C(F)(F)F)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C(C#N)=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(OC2=C1C(=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Br)C([H])=C([H])C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)S1)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C([H])C1=O
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]O\C(=C(\C#N)C(=O)N([H])C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])N(N=C1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=NN=C1C1=C([H])C([H])=C(N=C1[H])N(C1=C([H])C2=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])[C@]1([H])O[C@@]([H])(C([H])([H])C([H])([H])C2=C(F)C(F)=C(F)C(F)=C2F)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2O1)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C1=C2C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2=O)C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])OC2=C1C([H])=C(C([H])=C2[H])C1=C(C([H])=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(F)(F)F
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C2=C(F)C([H])=C(F)C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC([H])([H])C1=C(OC(=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])SC1=NC([H])=C(C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F
[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(=C([H])S1)[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C([H])=NC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C([H])=C(C([H])=C([H])C2=C([H])C([H])=C1[H])N1C(=O)N([H])N=C1C1=C([H])C(=NC([H])=C1[H])N([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3Cl)C([H])([H])C1([H])[H])C([H])=C([H])C(C#N)=C2[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)C1=NN=C(O1)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]([H])(N1C([H])([H])C([H])([H])N2C(=NC(OC([H])([H])[H])=C2[C@]1([H])C([H])([H])C([H])([H])C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])SC(OC2=C(Cl)C([H])=C([H])C([H])=C2Cl)=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C(Cl)C([H])=C(Cl)C([H])=C3[H])C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N([H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(N([H])C2=C3C([H])=NN(C3=NC(=N2)N(C([H])([H])[H])C([H])([H])C([H])([H])C#N)C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC2=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C(=C([H])C3=C([H])C(O[H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])(C(=O)O[H])[C@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(Cl)=C(N([H])C(=S)N([H])C([H])([H])[C@]23OC(O[C@@]2([H])[C@]2([H])OC(O[C@]2([H])C([H])([H])O3)(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@@]1([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2OC1(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=C(/C#N)C(=O)C([H])([H])SC1=NN=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])\C([H])([H])[H]
[H]C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C(=O)C1=C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(=O)N(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])[C@@]([H])(C(=O)N(C([H])([H])C(=O)ON([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
COC1=C(OC)C=C(\C=C\C=C\C(=O)C2=C(O)C=CC=C2O)C=C1
[H]N(C1=NC(N([H])C2=C(C([H])=C([H])C([H])=C2[H])S(=O)(=O)N([H])C([H])([H])[H])=C(Br)C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])N2N=C(N=C12)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])C1=C(N(N=C1[H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H]
[H]N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(OC1=C([H])C(C#N)=C([H])C([H])=C1[H])C2([H])[H]
[H]N([H])C(=N/C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])\C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]C1=NC2=C(C([H])=C1[H])C(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])=C(N(C2=O)C([H])([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N(C(=O)C1=C(N([H])C2=NN([H])C([H])=C2[C@@]1([H])C1=C([H])C([H])=C([H])O1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C([H])([H])C1=C(SC([H])([H])C([H])([H])C#N)S\C(S1)=C1\SC(SC([H])([H])C([H])([H])C#N)=C(S1)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=NOC(=C1[H])C1=C([H])C([H])=C(Cl)S1)C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=NC([H])=N2)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC(=NC(=N1)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(N1C(SC([H])([H])C(=O)OC([H])([H])[H])=NN=C1C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])[H])C(=O)C([H])([H])[H]
COC1=CC=CC(=C1)C1=NC(=NC(NC(C)=O)=C1)C1=CC(OC)=CC=C1
[H]OC(=O)C1=C(N([H])C(=O)N([H])[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC2=C3C(N([H])C4=C3C([H])=C([H])C([H])=C4[H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]1([H])C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(C#N)C([H])=NN2C(=N1)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NN=C(O1)C([H])([H])SC([H])([H])[H]
[H]C1=C([H])C(C#CC([H])([H])SC2=NSN=C2[C@]23C([H])([H])[N@@]4C([H])([H])[C@@]2([H])[C@@]3([H])C4([H])[H])=C([H])C([H])=C1Cl
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(N([H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2[H])N(C2=C([H])C3=C(C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])=C(C(=NC1=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])N([H])C(=O)[C@]1([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C1([H])[H])N([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=NN(N=N1)C1=C([H])C([H])=C([H])C(=C1[H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N=C(S1)C(=O)[C@]1([H])N(C(=O)[C@@]2([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)C2=C(C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C1=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NO[N+]([O-])=C1C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])OC(=O)C([H])([H])OC1=C([H])C(OC(=O)C([H])([H])[H])=C2C(=O)C([H])=C(OC2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[N+]([O-])=O)C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)N([H])C1=NC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C(N([H])[H])C2=C(S1)N=C(C([H])=C2C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(N(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])C(=O)N2C([H])([H])SC(C([H])([H])[H])(C([H])([H])[H])[C@@]2([H])C(=O)N([H])[C@@]2([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[C@@]2([H])O[H])C([H])=C1[H]
[H]C1=NC(=C(N1C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])N3C([H])=C(N=C23)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C(N([H])C2=NC(=NC([H])=C2[H])N([H])C2=C([H])C(=C([H])C([H])=C2[H])C(=O)N([H])[H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(SC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C(F)(F)F
[H]C1=C(C2=C([H])C([H])=C([H])N=C2N1[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])([H])C([H])([H])N1C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=N1
COC1=CC=CC(NC(=O)\C=C\C2=CC=CC=C2)=C1
[H]OC1=NC(=NC2=C([H])C([H])=C(OC([H])([H])[H])C(SC3=C([H])C([H])=NC([H])=C3[H])=C12)C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C(C(=C2N1C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2C([H])=C([H])OC2=C1[H]
[H]C1=C([H])C([H])=C(SC2=NN3C([H])=NC(=O)C(=C3C([H])=C2[H])C2=C(F)C([H])=C([H])C([H])=C2F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C(OC([H])([H])[H])(C(F)(F)F)C(F)(F)F)C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(Br)C(=C1[H])C(F)(F)F)C1=C([H])C([H])=C(OC2=C([H])C([H])=NC(=C2[H])C(=O)N([H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])N3C4=C(OC([H])([H])[C@@]3([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C24)C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])O[H]
[H]N(C(=O)C([H])([H])[H])[C@]([H])(C1=C(C([H])=C([H])C(Cl)=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(N([H])C(=O)C2=C([H])N=C(S2)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=NN1[H]
[H]N(C1=C(Br)C2=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1O[C@@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]N1C(=O)[C@]2(N(C(=O)[C@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=C1[H]
[H]C1=C([H])C(SC([H])([H])[H])=C2C(=C1[H])[C@@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C3OC([H])([H])OC3=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C3=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C4([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C([H])([H])[C@@]33C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]13[H])[C@]13C([H])([H])C([H])([H])N(C([H])([H])C4([H])C([H])([H])C([H])([H])C4([H])[H])[C@]([H])(C2([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H]
[H]N(C(=O)C([H])([H])N([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C2=C1OC(=C([H])C2=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])N(C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])C(F)(F)F)=C([H])C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C2=C1N(C(=O)C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C2([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C(Cl)=C1[H])C2=C1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)C2=C(O[H])C(=C(O[H])C([H])=C2[H])[C@@]2([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@]([H])(C3=C(O[H])C([H])=C(O[H])C([H])=C3[H])[C@@]2([H])C(=O)C2=C([H])C(O[H])=C(C(O[H])=C2[H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])C1=NN=C(N1C([H])([H])[H])[C@@]12C([H])([H])C([H])([H])[C@@](C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])(C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C1=C([H])C(=NC2=C1C([H])=C([H])C(=N2)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(C2=NN3C([H])=C([H])N=C3C(=N2)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1C([H])([H])[H]
[H]OC(=O)C1=C([H])N=C(OC([H])([H])[C@]2([H])N([H])[C@]([H])(C(=O)N3C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C#N)C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1(OC([H])([H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])(N([H])C(=O)N([H])[H])N([H])C(=O)N([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C(C([H])=C([H])S1)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])S(=O)(=O)C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]C1=C([H])C([H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C3=NN=C(C([H])=C3[H])C3=NN=C(O3)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C(F)(F)F
[H]N([C@]1([H])C([H])([H])C([H])([H])[C@](C(=O)N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C(=NC3=C2N=C([H])N=C3N2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C#C[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C2=C(OC([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(=C23)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)[C@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1N([H])C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C(S2)C2=C([H])N=C(S2)C2=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C(=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]C1=NN(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])N1C(=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C(=C([H])C([H])=C3[H])C(=O)N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)C2=C(C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])N3C([H])([H])C([H])([H])N(C4=C(Cl)C(Cl)=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])=C12
[H]OC([H])([H])[C@@]([H])(N([H])C1=C(C([H])=NC([H])=C1[H])S(=O)(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])F)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])OC(=O)C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H]
[H]C1=NC(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C2N=C(N(C2=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C1=C([H])N=C([H])C([H])=C1[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C3=NOC(=N3)C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(F)=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[C@@]([H])(OC([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C(C([H])=C([H])C3=NC([H])=NN23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H])[C@@]1([H])C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]11C(=O)N([H])C(=O)N([H])C1=O
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C1([H])C(C([H])([H])[H])(C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)=C1[H]
[H]N1C2=NC(=NC2=C(N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@@]2([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])SSC2([H])[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C2=C([H])C(OC3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C([H])C([H])=C12)C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N1C(=C([H])C2=NC(=NC(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C12)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC(=O)[C@]1([H])N(C(=O)C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2[C@@]2([H])C([H])([H])OC([H])([H])[C@@]12[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1[H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C#N)C(=C1[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])N([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N([H])C([H])([H])C2=C([H])C([H])=C([H])O2)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1Cl)C1=C([H])N=C2C([H])=C([H])C(=NN12)N([H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])[C@@]2(N([H])[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)[C@@]22C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C2([H])[H])C1=O
[H]OC1=C2C(OC(=C2C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C(Cl)C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(OC1=C([H])C([H])=C(SC([H])([H])C2=NC(=NS2)C2=C([H])C([H])=C(OC(F)(F)F)C(Cl)=C2[H])C([H])=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(Br)N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C2=C1N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])N=C([H])C([H])=C1SC([H])([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C3C(=C2O1)C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]3([H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1O[H])C([H])([H])C([H])([H])[N+]1=C([H])C3=C(O[H])C(O[H])=C([H])C([H])=C3C([H])=C21
[H]N1C(SC([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=NC2=C(C([H])=C([H])S2)C1=O
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])[C@@]([H])(N(C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C1=C([H])C(F)=C(OC([H])([H])[H])C([H])=C1[H]
CC(C)CC(NC(=O)[C@@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)C1CCCN1C(=O)C(CCCNC(N)=N)NC(=O)[C@@H](C)CCC[N](C)(C)C)C(C)(C)C)C(O)=O
[H]OC(=O)C1=C([H])N=C([H])C(=C1[H])C1=C(C([H])=C([H])S1)C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(SC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C2=C1C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=C(N=C(S1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C(Br)=C1[H])N1C(=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1OC1=C([H])C([H])=C(Cl)C([H])=C1OC([H])([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C(=O)N([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@](N([H])C(=O)O[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N1C2=C([H])C(C#CC3=C([H])C([H])=C([H])C([H])=C3[H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C2N=C(C2=C([H])C([H])=C([H])C(C#N)=C2[H])C([H])([H])C1=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=NC3=C(N2C([H])=C1[H])C(=O)N(C(=O)N3C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C1=NC(=C(N21)C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(F)(F)F)C(F)(F)F)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(S1)S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(C([H])=C(N([H])C(=O)[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C(=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C(Cl)C(=C1[H])C1=NN([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])N=C([H])C([H])=C1OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N1C2=NC3=C(N2C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(I)C([H])=C(C([H])=C1Cl)S(=O)(=O)N([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])N(C(=O)[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2=C(Cl)C([H])=C(C([H])=C2Cl)C([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@](=O)(O[H])O[P@](=O)(O[H])OC([H])([H])[C@@]2([H])O[C@@]([H])(C3=NC(=C([H])S3)C(=O)N([H])[H])[C@]([H])(O[H])[C@]2([H])O[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])[C@]([H])(C2=C(\C([H])=N\OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C(=C([H])C(=C2N([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1N([H])C([H])=C2[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])[C@@]2([H])C([H])=C(C3=C([H])N=C([H])C(OC4=C([H])C([H])=C([H])C(OC([H])([H])[H])=C4[H])=C3[H])C([H])([H])[C@@]([H])(C1([H])[H])C2([H])[H]
[H]N(C(=S)N([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C2O[C@@]3([H])[C@]([H])(N([H])C(=O)C(\[H])=C(/[H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])[C@@]4(OC(=O)C([H])([H])[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]C1=C([H])C(C2=NN=C(N2C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2Br)=C(C([H])=C1[H])C(F)(F)F
[H]C1=NC(=C([H])C([H])=C1[H])C1=NN(N=N1)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C2OC(OC2=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1[H])C([H])([H])C1=NC2=C(C(=NN2C2=C(Cl)C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C([H])([H])[H])C(=O)N1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]2([H])C(=O)N(C(=O)[C@]12[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C1=C([H])C2=C(Cl)C([H])=C([H])N=C2C([H])=C1[H])C([H])([H])C([H])([H])[H])C(=O)O[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])S[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]OC1=C(N(C([H])([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C12)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2N(C(SC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C(=C3[H])[N+]([O-])=O)=NC2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN=NN1C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C(C([H])=C3[C@]2([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(F)(F)F
OC1=C2C(=O)C=C(OC2=CC(OCCON(O)=O)=C1)C1=CC=CC=C1
[H]OC(=O)[C@@]([H])(N1C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(S[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C1=NC2=C(C([H])=C([H])C(=C2[H])C([O-])=O)C2=C1N=C(N=C2[H])N([H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(N=C(N1[H])C([H])([H])N(C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C1=NC2=C(OC([H])([H])[H])C([H])=C([H])C(N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])=C2S1
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=O)N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])C2=O)C([H])([H])C1([H])[H]
[H]C1=C([H])C(F)=C(C(=O)C(=O)C2=C(F)C([H])=C([H])C([H])=C2F)C(F)=C1[H]
[H]C1=C([H])C([H])=C2C(=O)N(SC2=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(F)=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])N2C([H])=C([H])C([H])=C2C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])S[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)N([H])[C@]([H])(C1=O)C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([N-]S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C(C(OC([H])([H])C([H])([H])OC2=NC([H])=C(OC([H])([H])[H])C([H])=N2)=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OP(=O)(O[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1(C(=O)N(C([H])([H])C1([H])[H])[C@@]([H])(C1=NN([H])C(=S)N1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=NC([H])=C2C([H])=C1[H])[C@@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(F)=C(F)C([H])=C1C1=C([H])C([H])=C(N=C1[H])C([H])([H])[H]
[H]N(OC([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C(S1)N(C(=O)N(C1=NN=C(OC([H])([H])[H])C([H])=C1[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C2=NC(=NO2)C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=NC(Br)=C(S2)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C1=C2C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C(=NC(=C1C1=C([H])C2=C(C([H])=C1[H])N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])S1
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])N3[H])C2=C1[H]
[H]OC(=O)C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
[H]N(C(=O)OC([H])([H])C1(C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])SC1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@](N([H])[H])(C([H])([H])OP(O[H])(O[H])=C([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1Cl)C1=C([H])C([H])=C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C(O[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])F)=C([H])C2=C13
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(C([H])=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(O1)C(\[H])=C1/SC2=NC3=C(C([H])=C(C([H])=C3N2C1=O)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])N(N=C1C1=C([H])C([H])=C(C#CC2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C1=C(N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C#N
[H]OC(=O)C(=C(/C(=O)C1=C([H])C([H])=C2OC([H])([H])C([H])([H])OC2=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])\C1=C([H])C2=C(OC([H])([H])O2)C(OC([H])([H])[H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C(=C1C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)N3C(=C(C2=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C1=NN(\C(S1)=N\C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C#CC2=C(C(Cl)=NC([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)OC1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H]
CCN(C)C1=CC(=CC(COCC2(CCN(C)CC2)C2=CC=C(F)C=C2)=N1)C(F)(F)F
[H]N(C1=NN2C(=C([H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])=N1)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])N(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])OC1=C2C(O[C@]([H])(C3=C2C([H])=C([H])C2=C3C(=C([H])C(N2[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])=C([H])[H])=C([H])C([H])=C1[H]
[H]N1C(=O)C(C2=C([H])N(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[H])=C(C1=O)C1=C2N(C3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]O[C@@]([H])(C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])C([H])=C1[H])C([H])([H])[H])[C@@]([H])(O[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=C(SC(=N1)N([H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]C1=C([H])C([H])=C(C(Cl)=N1)[C@]([H])(OC1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N(C(=O)N1C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])N=C2C(C([H])=C([H])C([H])=C2C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C1([H])[H])C([H])([H])[C@@]([H])(O[H])[C@@]1([H])[C@]3([H])C([H])([H])C([H])([H])[C@]([H])([C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])S(=O)(=O)O[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
CC(C)[C@H](NC(=O)C1=CC=CN=C1)C(=O)N1CCC[C@H]1B(O)O
[H]N(C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=NC(=C2[H])C2=NC([H])=C(N2[H])C(F)(F)F)C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])[C@]([H])(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(C(=C1C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N1C(=O)C2=C(C1=O)C1=C(N3C4=C1C([H])=C([H])C([H])=C4C([H])([H])N([H])C([H])([H])C3([H])[H])C1=C2C2=C(N1[H])C([H])=C(F)C(F)=C2[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C2C(OC3=C2C([H])=C([H])C(N([H])[H])=C3[H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C([H])C2=C1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C(=C([H])C(F)=C1[H])C1(OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])[H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N2C(=O)[C@](N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]3([H])N(C(=O)[C@@]4([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[C@]([H])(O[H])C3([H])[H])C([H])([H])C3=C([H])C([H])=C([H])S3)C([H])([H])O[H])(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])[C@@]2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C(=C([H])N(C(=O)C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C1[H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N1C(=S)N([H])C2=C(C(=C([H])S2)C2=C([H])C([H])=C([H])O2)C1=O
[H]N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(I)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C(OC([H])([H])[H])C([H])=C(C([H])=C3[H])C3=NC(=C(S3)C([H])([H])[H])C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N([H])C1=C(C(=NN1[H])C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(N=C(S2)N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
O=C(CSC1=NC(C2=CC=CC=C2)=C(N=N1)C1=CC=CC=C1)C1=CNC2=C1C=CC=C2
[H]N(C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=C(S1)C([H])([H])[H])[C@]1([H])C([H])([H])C(=O)N([H])S1(=O)=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(C1=C([H])C([H])=C(O[C@]2([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C2=C(O1)C([H])=C([H])C(=C2[H])C(=N[H])N([H])[H]
[H]C1=C(SC2=NN=C(O2)C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S1(=O)=O
[H]C1=C([H])C([H])=C2C(=C1[H])N(N=C2C(=O)OC([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C(O[C@]2([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]2([H])O[H])=C([H])C(Cl)=C1[H]
OCC1=CC(OCC(O)CNC2CCN(CC2)C2=NC=NC3=C2C(=CS3)C2=CC=CC=C2)=CC=C1
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=C([H])C([H])=C2N=C([H])C3=C(N(C(=O)C([H])=C3[H])C3=C([H])C(=C(F)C([H])=C3[H])C(F)(F)F)C2=C1[H]
[H]OC(=O)C([H])([H])N([H])C(=O)[C@@]([H])(C(=O)O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C([H])C([H])=C(F)C([H])=C2N2C1=NN=C2C(F)(F)F)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])[H])=C1C1=NC(N([H])[H])=C(C#N)C(=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C(N=C(O1)C1=C2C([H])=C([H])C(=NC2=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])[C@@]1(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])O[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=NC(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(I)C([H])=C1[H])C([H])([H])C([H])([H])F
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(O[C@]([H])(N2C(=O)C([H])([H])[H])C2=NC(=C([H])C([H])=C2[H])C([H])([H])[H])N=C(SC([H])([H])[H])N=N1
[H]OC(=O)C(\[H])=C(\C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2C1=C([H])C(=C([H])C(=C1OC([H])([H])C([H])([H])C([H])([H])F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(C(=O)C(=O)N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])=C1C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C(\[H])=C(/[H])C3=C([H])C([H])=C(C([H])=N3)C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[H])[C@]3([H])[C@]([H])(OC(=O)[C@]3([H])C([H])([H])[C@]2([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])([H])C2=C(C3=C([H])C([H])=C([H])C([H])=C3S2)C([H])([H])[C@]1([H])C(=O)OC1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(OC([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])N=C(C([H])=N1)C1=C([H])N(N=C1[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])N(C(=O)[C@@]1([H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C1=[N+]([O-])C([H])=C([H])C([H])=C1[H]
[H]C(=C(C#N)C#N)C1=C([H])N(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C(Cl)C(=N1)N([H])C1=C(F)C([H])=C([H])C([H])=C1C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C2N(C(=O)C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])OC2=C1[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N(C1=NC2=C(O1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC([H])=NC(N2C([H])([H])C([H])([H])N(C(=O)N([H])C3=C([H])N=C(OC4([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])=C1\C([H])=N\OC([H])([H])[H]
[H]OP(=O)(O[H])C([H])([H])[P@](=O)(O[H])C([H])([H])C1=C([H])C([H])=C(N([H])C2=NC([H])=C3C([H])=C(C(=O)N(C3=N2)C([H])([H])[H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(OC1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])[C@]1(N([H])C([H])([H])C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C(F)C(=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]N(C(=O)[C@]1(N([H])N=C(C1([H])[H])C(F)(F)F)C([H])([H])[H])C1=C([H])C([H])=C(C#N)C(=C1[H])C(F)(F)F
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1Cl)[C@@]([H])(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)N1C2=C(C([H])=C(F)C(Cl)=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])N=C2C([H])([H])[H])N=C1[H]
[H]N(\N=C(\N([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C3=NOC(=N3)C([H])(C([H])([H])[H])C([H])([H])[H])C(F)=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC1=NC(=C(N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C(=O)C(=O)C2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])C(=O)C([H])([H])OC1=C(OC([H])([H])C([H])([H])[H])C([H])=C(\C([H])=C2\S\C(=N/C3=C4C([H])=C([H])C([H])=C([H])C4=C([H])C([H])=C3[H])N([H])C2=O)C([H])=C1I
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]C1=C(Cl)C([H])=C([H])C(OC([H])([H])[C@@]2(C([H])([H])[H])C([H])([H])N(C(=O)N3C([H])([H])C([H])([H])N(C(=O)C4(C([H])([H])[H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=N1
[H]N(\N=C1/C(=O)N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)[C@@]([H])(N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])F)C([H])([H])C1([H])[H]
[H]ON(C([H])=O)[C@]([H])(C([H])=C1C([H])([H])C([H])([H])N(OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N1C2=C([H])C([H])=C(F)C([H])=C2[C@]([H])(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])=C(C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C2OC([H])([H])OC2=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=O)C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3O2)C([H])([H])C1([H])[H]
[H]C1=C([H])N=C(S1)C1=NN(C([H])=C1[H])C1=C2C(=NC([H])=C1[H])N(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1C([H])(F)F)C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C([H])=C([H])C([H])=C2OC([H])([H])[H]
Cc1cnc(nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1)-c1ccccc1
OCCONC(=O)C1=C(NC2=CC=C(I)C=C2F)C2=C(NN=C2)C=C1
[H]N(C#N)C(=N\C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H])\N1C([H])([H])C([H])([H])C(=C2C3=C(C([H])=C(Br)C([H])=N3)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C([H])C2=C(C([H])=C1[H])N(C([H])([H])[H])[C@]1([H])[N@+]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]21C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1SC1=C2C([H])=C(F)C(N([H])C([H])([H])C([H])([H])[H])=C1[H])C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])[C@]1([H])C([H])([H])O[C@@]([H])(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C1=NC2=C(SC([H])=C2[H])C(=N1)C1=C([H])C([H])=C([H])O1
[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C(C#N)C([H])=C3C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[C@@]2([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C(\[H])=C(/C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(C2=C([H])C([H])=C([H])O2)=C(N=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C(N=C(N=C1[H])C([H])([H])[H])N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])[S@](=O)C([H])([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2Cl)C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C2C(=NC3=NC(OC([H])([H])[H])=C(C#N)C([H])=C13)C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])[H])[C@@]1([H])C([H])([H])C2=C([H])N([H])N=C2C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
Cc1cnc(NCCc2ccccc2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
CC1=CC=C(C(C)=C1)S(=O)(=O)N1CCC(CC1)C(=O)NC1=CC=CC=C1Br
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2C#N)C([H])([H])C1([H])[H]
[H]OC1=C(C(=O)C([H])([H])[H])C(O[H])=C(C(O[H])=C1C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C(\C([H])=C(/[H])C(=O)N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N([H])[C@]([H])(C(=O)N2[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]23[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)N3C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C2=O)C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]N(\C([H])=C1/C(=O)N([H])C(=O)N(C1=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=S)S\C(=C(\[H])C2=C([H])C3=C(OC([H])([H])C(=O)N3C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1=O
[H]OC(=O)C1=C([H])C([H])=C(OC([H])([H])C#N)C(=C1[H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C(C([H])=C(OC2=C([H])C([H])=C(C([H])=C2N([H])C(=O)C2=C([H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C(F)(F)F)C([H])=C1[H])C(=O)O[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C(C(=O)OC([H])([H])[H])C(=C([H])S1)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CO[C@H](C[C@H](CCN(C)C)C(=O)NO)C1=CC=C(F)C=C1
[H]N(C(=O)C([H])([H])C([H])([H])N1C(=O)N([H])C(=O)C2=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C(F)=C([H])C2=C([H])N(N=C12)C1=C([H])C([H])=C(N([H])C(=O)[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C(F)=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC(=NC(=C1[H])C1=NC([H])=C([H])S1)N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C2=NC([H])=NC(N([H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)=C2C([H])=N1
[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=C([H])C([H])=C(OC(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C(=O)C3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])[C@@]4([H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C(C(=O)N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])N1C([H])([H])C(=O)N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C([H])=C([H])C2=C1C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(Cl)=C3Cl)C([H])([H])C([H])([H])C1([H])[H])C([H])=C2[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N1C([H])=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C1=O)C([H])([H])C([H])([H])[H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(SC2=C([H])C(OC([H])([H])C3=C([H])N=C([H])C([H])=C3[H])=C([H])C([H])=C2[H])C(=C1C(F)(F)F)C(F)(F)F)C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)N1C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])=O)N([H])[H]
CC1=CC(=CC(C)=C1)C(C)(C)CN(CC(=O)NC(CCCN=C(N)N)B(O)O)C(=O)CCC1=CC=CC=C1
[H]N(C1=NC(=C([H])C([H])=N1)N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C([H])C(=NC([H])=N2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)N([H])C1=C(C([H])=C(S1)C#CC1=C([H])C([H])=C([H])C(N([H])C(=O)C2([H])C([H])([H])C2([H])[H])=C1[H])C(=O)C([H])([H])[H]
[H]O[C@]1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])OC4=C([H])C([H])=C5C([H])=C([H])C([H])=C([H])C5=C34)[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=NC([H])=NC(N([H])C3=NN([H])C(=C3[H])C([H])([H])C(=O)N([H])C3=C(F)C(F)=C([H])C([H])=C3[H])=C2C([H])=C1OC([H])([H])[H]
[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])C(=O)C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(=O)[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C([H])=C2O[C@](C([H])=C([H])C2=C1[H])(C([H])([H])[H])C([H])([H])O[H]
[H]N(C(=O)C1=NC(F)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[P@@](=O)(OC([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)[C@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)N([H])[C@@]([H])(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[H])C(=C23)C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]C1=C2C(=C([H])C(F)=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C(N=C(N1C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]\C(=C(\[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C(N=C(S1)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]1([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[H])[C@@]([H])(SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(OC2=C(F)C(=C(F)C(OC3=C([H])C(=C([H])C([H])=C3[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])=N2)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]([H])(N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])SC([H])=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])N(\C(S[H])=N\C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C(=O)C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(O[H])=C1[H]
[H]N(C(=O)C1=C([H])C(N([H])C2=NC(=C([H])S2)C2=C([H])C([H])=C([H])N=C2[H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])N1C([H])=NC(=C1[H])C([H])([H])[H])C(F)(F)F
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C(C3=C(C([H])=C(OC([H])([H])C([H])([H])[C@@]([H])(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])[H])C1([H])[H]
[H][C@]12CC[C@]([H])(C[C@H](C1)OC1=CC=CC(=C1)C(N)=O)N2C(C)C1=CC=C(C)S1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])C(Cl)=C([H])N2[H]
[H]N1N=C(N(\N=C(/[H])C2=C([H])C([H])=C(O2)C([H])([H])[H])C1=S)C1=NN([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])[C@]([H])(N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C(Cl)S1)[C@@]1([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])C1(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1
ON(=O)C1=CC=C(C=C1)N1CC2CC(C1)N2
[H]C1=C([H])C(N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C2C([H])=NC(=C([H])C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1(C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3Cl)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)OC([H])(C(F)(F)F)C(F)(F)F
[H]ON([H])C(=O)[C@@]1([H])N(C([H])([H])[S@@](=O)C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OS([O-])(=O)=O)C([H])=C1[H])C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C(=O)O[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)O[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C2N=C([H])C([H])=C([H])C2=C1[H])C([H])([H])[C@]([H])(C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C(C(=O)N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])C2=NC([H])([H])C([H])([H])C([H])([H])N2[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H]
OB(O)[C@@H]1CCCN1C(=O)CNC(=O)C1=C2C=CC=CC2=CC=C1
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=N2)N2C(=O)N(N=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C2=C(N=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1S2)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C2=C(N([H])N=C2[H])C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(OC1=C(Cl)C([H])=C([H])C(=C1[H])C([H])([H])N1C2=NC(Cl)=C([H])C([H])=C2C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N(C(=O)C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C2C([H])=C([H])N([H])C2=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C3=C(S2)C([H])=C([H])C(F)=C3[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(\C([H])=C(/[H])N2C([H])=NC3=C([H])N=C([H])N=C23)=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])N1C([H])=NC(=C1[H])C([H])([H])[H])C(F)(F)F
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C1=C(C2=C(S1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=NN=C(SC([H])([H])C(=O)N([H])N([H])C(=O)C([H])([H])Cl)N1N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[C@]1([H])N(C(=O)C3=C([H])C4=C(C([H])=C3[H])C([H])([H])C([H])=N4)C([H])([H])C([H])([H])C([H])([H])[C@@]21[H]
[H]N([H])C(=O)C1=C(O[C@@]([H])(C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C(S1)N1C([H])=NC2=C1C([H])=C(C([H])=C2[H])C1=C([H])N(N=C1[H])C([H])([H])[H]
[H]O[C@@](C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])[H])(C([H])([H])[H])C(F)(F)F
[H]N(C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]1([H])C2=C([H])C(=O)C(SC([H])([H])[H])=C([H])C([H])=C2C2=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N(C(=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[C@@]1([H])N([H])C(=O)N([H])C1=O
[H]O[C@@]1([H])[C@@]2([H])O[C@]([H])(C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC3=C([H])C(Cl)=C(C([H])=C23)C([H])([H])C2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C2[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]OC(O[H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(F)(F)F
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)C1=C([H])C(=NC(SC([H])([H])[H])=N1)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C(=O)[C@]([H])(N([H])C(=O)[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])N2N1C(=O)C(C2=O)(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N2C(=O)N(C(=O)[C@]2([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C(C([H])=C1Cl)C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])[C@]1(N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])N(C(=O)C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]1([H])N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(C#N)C([H])=C1C1=C([H])N=C2N=C(SC2=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC2=C(N(N=C2C([H])([H])[H])C2=C([H])C(Cl)=C(C#N)C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1F
[H]OC1=C([H])C([H])=C2C(OC([H])([H])[C@@]([H])(N3C([H])([H])C([H])([H])C(O[H])(C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])C3([H])[H])[C@@]2([H])O[H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])SSC([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])[C@@]2([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@@]12[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])=NC(=C2C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OP(=O)(OC2=C([H])C([H])=C(N([H])C(=O)C([H])([H])N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])[C@]2([H])N(C(=O)[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[N+]3([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]SC([H])([H])[C@]1(C(=O)N([H])[C@]([H])(C(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C(=C([H])C([H])=C2N1[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(Cl)=C2[H]
[H]OC(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C(N=C(O2)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C3=C([H])C4=C(C([H])=C3[H])C([H])([H])C(=N4)C([H])([H])[H])[C@@]1([H])C2([H])[H]
[H]N1C(=C([H])C2=C1C1(C([H])([H])N([H])C2=O)C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC(=N1)C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C(ON=C1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=O)C(=O)C2=C([H])C([H])=C([H])C([H])=C12
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@@]1(N([H])C(=O)N([H])C1=O)C([H])([H])N1C(=O)C2=C(C([H])=C([H])C(Cl)=C2[H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])[C@]2([H])C1([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=O)C([H])([H])[H])=NN1C([H])([H])[H]
[H]C1=C(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C(=NC3=C2C([H])=C([H])N=C3[H])C([H])([H])[H])C2=C(Cl)C([H])=C([H])C([H])=C2N1C(=O)N(C([H])([H])[H])C([H])([H])[H]
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C2=NC=CN2C)C(=N1)N1CCOC[C@@H]1C
[H]N(C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C(=O)N1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]C1=C([H])C2=C3N(C([H])([H])C([H])([H])C([H])([H])S2)[C@@]2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])[C@@]2([H])C3=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])[C@]([H])(N([H])[C@@]1([H])C([H])([H])[H])C(=O)N(C([H])([H])C#N)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC2=C(S1)C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C(Cl)=C3Cl)C([H])([H])C1([H])[H])=C2[H]
[H]OC1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])\N=C(/S[H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])N([H])C(=O)C1=C(OC([H])([H])[H])C([H])=C(O[H])C2=C1OC1=C([H])C(O[H])=C(C(=O)C([H])([H])[H])C(=O)[C@@]21C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C(=O)N([H])C([H])([H])[C@@]([H])(N([H])C2=C(C([H])=C([H])C([H])=C2[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])[C@]2(OC3=C(C([H])=C([H])C([H])=C3[H])[C@@]([H])(O[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=NC([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(C#N)=C(OC([H])([H])[H])C([H])=C1SC([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])\N=C(/[H])C1=C([H])C([H])=C([H])N1C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])[C@]4([H])C(=C([H])C([H])([H])[C@]5([H])N([H])[C@@]([H])(OC([H])([H])[C@@]45C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]3([H])C(=O)C([H])([H])[C@]2(C([H])([H])[H])[C@@]1([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C2N=C([H])C([H])=C([H])C2=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(=C([H])C(=O)N2[H])C(F)(F)F)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NN(C2=NC(SC([H])([H])C([H])([H])C([H])([H])[H])=NC(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C12)C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(OC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([O-])=O
CC1(C)CCN([C@H]2C3CC4CC2C[C@@](O)(C4)C3)C(=O)C2=C1N(N=C2)C1=CC=C(F)C=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(C(=O)OC2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C(N=C(C(=N1)C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC(=C([H])C2=NC([H])=C([H])C([H])=C12)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])SC([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[C@]3([H])C([H])([H])[C@]3(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C3=C1[C@]1(C(O3)=C([H])C(O[H])=C(C(=O)C([H])([H])[H])C1=O)C([H])([H])[H])C(=O)N(C(=O)N([H])C([H])([H])C1=C([H])OC([H])=C1[H])[C@@]([H])(OC([H])([H])[H])O2
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C(F)=C12)C(=O)[C@]1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C(Br)SC(=C1[H])S(=O)(=O)N1N=C(C2=C([H])C([H])=C([H])C(Br)=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[C@]1([H])N([H])C(=O)N([H])C1=O
[H]N([H])C1=N[C@@](C(=O)N1C([H])([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])C([H])=C([H])C1=C(C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C2=O)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=CN=C(CNCC2(F)CCN(CC2)C(=O)C2=COC=C2)C=C1
[H]N(C(=O)C1=C([H])C([H])=C(O1)C([H])([H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C2=NC(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=N2)C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C([H])=C(OC2=C([H])C([H])=C(C([H])=C2N([H])C(=O)C2=C([H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C(=O)OC([H])([H])[H])C([H])=C1[H])C(=O)O[H]
[H]N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N2C1=NN=C2C([H])([H])C([H])([H])[H]
[H]N1C2=C(C([H])=C([H])C(=C2[H])C(F)(F)F)C2=C1C([H])=C1N([H])C(=O)C([H])([H])C([H])([H])C1=C2[H]
[H]C1=C([H])C(=C([H])C(F)=C1N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C2C(=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])[C@@]1([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=NN=C(S1)N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C(F)=C([H])C([H])=C2Br)C([H])([H])C1([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@]1([H])C2=C([H])C([H])=C(N=C2OC2=C1C([H])=C([H])C([H])=C2[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=NN=C([H])S1
[H]C1=C([H])C(C2=NN(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N([H])C([H])([H])C([H])([H])C1=C([H])C(I)=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
CC(C)(CC(O)(CC1=CC2=CC=NC=C2N1)C(F)(F)F)C1=CC(=CC=C1O)C1=CC=CN=C1
[H]OC1=C(C([H])=C(\C([H])=C(/[H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N(C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])N(C1=C(Cl)C([H])=C([H])C(Cl)=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C2=C(N([H])C([H])=C2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)OC([H])([H])C([H])([H])[H])C1=NC(=C(S1)C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)N([H])C(=O)C(OC2=C([H])C([H])=C(OC3=C([H])C([H])=C(C([H])=C3[H])C3=NC(=C([H])O3)C3=C([H])C([H])=C([H])C(F)=C3[H])C([H])=C2[H])(C1=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(O[C@]3(C(=O)N([H])C(=O)[C@@]([H])(N([H])[H])C3=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]O\N=C1/C([H])([H])N([C@@]([H])(C(=O)N([H])O[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=NC(=C1C1([H])C([H])([H])C([H])([H])N(C2=NC(=NC([H])=C2C2=C([H])C([H])=C(F)C(=C2[H])C([H])([H])[H])C([H])([H])C#N)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C(Cl)C([H])=C(N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])C3(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2=O)C(Cl)=C1[H]
[H]O\N=C(/[H])C1=C(O[H])C(Cl)=C(C([H])=C1[H])C1=C([H])C(F)=C(O[H])C([H])=C1[H]
[H]N([H])C1=NC(SC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3Cl)C([H])([H])C2([H])[H])=NC(N([H])[H])=C1C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N(C1=C(N=C2C([H])=NC([H])=C([H])N12)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H][C@](N)(CCCCN)C(=O)N1CCC[C@H]1B(O)O
N[C@H](CC1=CC=C(Cl)C=C1)C(=O)N1CCN(CC1)C1=CC=NC2=C1NC=C2
[H]N([H])[C@@]1([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=NC([H])=C2C([H])([H])C(=O)C2=C([H])C([H])=C([H])C(=N2)C2=C(F)C(=C([H])C([H])=C2F)C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)[C@]1([H])OC2=C(N=NC(SC([H])([H])[H])=N2)C2=C(C([H])=C([H])C([H])=C2[H])N1C(=O)C([H])([H])[H]
[H]C([H])=C([H])C(=O)N([H])C1=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=N1
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=NN(C(=O)C([H])([H])C([H])([H])[H])C(SC([H])([H])[H])=N1
[H]C1=C([H])C2=C(N=C(S2)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C2N([H])C([H])=C([H])C2=C1C([H])([H])[H])C1=C(C#N)C([H])=NC([H])=C1C1=C([H])C([H])=C(O1)C([H])([H])N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(OC3=C(C([H])=C(Br)C([H])=C3[H])[C@@]3([H])O[C@]([H])(C([H])([H])N4OC5=C4C([H])=C(C([H])=C5[H])N4C(=O)C([H])([H])C4([H])[H])C([H])([H])[C@@]23[H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])N1N=C(C([H])=C1N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(OC([H])([H])[H])C(C2=C(SC3=C(N(C([H])([H])C4([H])C([H])([H])C4([H])[H])C([H])([H])[C@]4([H])C([H])([H])OC([H])([H])C4([H])[H])C(OC([H])([H])[H])=NN23)C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])OC([H])([H])[H]
[H]N(C(=O)C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C(C([H])=C1[H])C1=C([H])C([H])=NC(=C1[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C(C#N)=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2N=C1Cl
[H]N(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])[C@@]1(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=NC(=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1C#N)C([H])([H])N(N1C([H])=NN=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C(=N\C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]1([H])C([H])([H])N([H])[C@@]([H])(C(=O)N([H])[H])C1([H])[H])\N([H])[N+]([O-])=O
[H]OC(=O)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(OC([H])([H])[C@@]3([H])OC4=C(C([H])=C([H])C([H])=C4[H])N(C([H])([H])[H])C3([H])[H])C(OC([H])([H])[H])=C2[H])C2=C1C([H])=C(F)C([H])=C2[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C1(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C(F)=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C2=C(O1)C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C2C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C2=C(C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])[H])C([H])([H])C2=NC(N([H])[H])=C([H])C([H])=C2[H])C([H])([H])N(C1=O)C([H])([H])[H]
[H]N1C2=NC([H])=C(Br)C(N3C([H])([H])C([H])([H])N(C([H])([H])C4=NOC(=C4[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C2N=C1C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H])S(=O)(=O)C1=C([H])C(F)=C(OC([H])([H])[H])C([H])=C1[H]
CN1CCC(COCC2=NC(=CC(=C2)C(F)(F)F)C2CC2)(CC1)C1=CC=CC(F)=C1
[H]C1=C(N(C(=C1C(=O)C([H])([H])SC1=NN=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC1=NC(OC2=C([H])C(=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])N([H])[H])=C(F)C(N([H])C([H])([H])[H])=C1F)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)O[C@]([H])(C([H])([H])C1=NN=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NN([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(C#CC2=C([H])N=C3C([H])=C([H])C([H])=NN23)=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]OC1=C(C([H])=C(\C([H])=C2/SC(=O)N([H])C2=O)C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1OC([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C(=O)N([H])C1=C([H])C([H])=C2N=C(SC([H])([H])C(\[H])=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@](C1=C([H])C(Cl)=C([H])C([H])=C1[H])(C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])[C@@]1([H])C([H])([H])N(C(=O)N([H])[C@]([H])(C([H])([H])N([H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]\C(=C1/C(=O)N2C(=C([H])S[C@]12[H])C([O-])=O)C1=C([H])C2=C(S1)C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(=N1)C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)O[H]
[H]OC1=NSC(N([H])C2=C([H])C([H])=C(OC3=C(Cl)C(=C([H])C([H])=C3[H])C(F)(F)F)C([H])=C2[H])=C1\C(=N\[C@]([H])(C([H])([H])[H])C([H])([H])O[H])N([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(Br)=C(OC2=C([H])C([H])=C(O[H])C(=C2[H])C(=O)N([H])C([H])([H])C([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C(Br)=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C1(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1N=C2C3=C(SC(=C3C([H])([H])C([H])([H])C2=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(C#N)=C([H])C(Cl)=C2O1
CC(C)=CC1=C(O)C(C=C(C)C)=C2OC(=CC(=O)C2=C1O)C1=CC=CC=C1
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]OC(=O)C(=O)N([H])C1=C([H])C([H])=C2C3=C(C4=C([H])C([H])=C(C(F)=C4N3[H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C1[H]
COC1=CC2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=C(OC)C=CC(=N3)C3=CC=C(C=C3)S(=O)(=O)NC3CC3)C2=O)C=C1
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
NC(=O)C1=C(NCCO)C2=C(C=C(C=C2)C2=CC=NC=C2)N=N1
[H]N(C1=C2N=C([H])N(C2=NC(=N1)C#N)C1=C([H])C(F)=C([H])C(F)=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(Br)=C2C3=C([H])C(O[H])=C(O[H])C([H])=C3N(C(=O)C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])[H])C2=C1O[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]OC1=C2C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C2C(=C1[H])[C@]([H])(N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C2N1C([H])=C([H])N=C2N([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1N=C([H])C2=C1C([H])=C([H])C1=C2C([H])([H])[C@]2(C1=C(C(=O)C([H])([H])C2([H])[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N([H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC(=O)C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])C1=C([H])C(=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])O[H])C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])[C@@]3([H])C([H])([H])[C@@]3(C3=C([H])C([H])=C(F)C([H])=C3[H])C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C1=NC(=NO1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(C#N)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]OC1=C([H])C2=C(C(=O)C3=C(C([H])=C(O[H])C([H])=C3O2)C([H])([H])[H])C(O[H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C2N(C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(OC(=O)C3=C([H])N=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1=NC([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])F
[H]OC([H])([H])[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])OC([H])([H])C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])[N+](=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C(C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(OC2=C(N([H])C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3S(=O)(=O)N([H])[H])C([H])=C([H])C(=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C(=O)N([H])C(=C(C(=O)OC([H])([H])[H])[C@@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(C2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])(C2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=NO[C@]2(C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])N([H])C3=NC4=C(N3[H])C([H])=C([H])C([H])=C4[H])C2([H])[H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])N(C(=O)C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N(C([H])([H])C(=N/OC([H])([H])[H])\C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1\C(=N\OC([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)C2=C([N+]([O-])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]S\C(=N/C1=C([H])C2=C(C([H])=C1[H])N(C(=C2[H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2C(=C([H])C(=C1[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])O[C@]2(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])C([H])([H])N1C2=C([H])C([H])=C(C#N)C([H])=C2C([H])([H])[C@@]([H])(N(C([H])([H])C2=C(ON=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=N2)C1([H])[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C(F)=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(N=C(C([H])=C1[H])C(F)(F)F)N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1(N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C(C(N2C3=NC(=C(N3C([H])([H])C([H])([H])C2([H])[H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C(F)(F)F)C(F)(F)F)=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1=C(N([H])[H])C2=C(F)C([H])=C([H])C([H])=C2N=C1C([H])([H])[H]
[H]OC1=C(C([H])=C(\C([H])=C(/[H])C2=C([H])C(=NO2)C([H])([H])[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C#N
[H]N(\N=C(/[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C(=O)C1=C([H])[N+](=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])=C(C(=O)N2C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=NC([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]OC(=O)C1=C([H])C(=C2C([H])=C(C([H])=C([H])C2=N1)C1=C([H])C([H])=C(OC([H])([H])C2=C(ON=C2C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])S1)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(OC2=C([H])C(N3C([H])([H])C([H])([H])N(C4=C([H])C([H])=C([H])C(=C4[H])C(F)(F)F)C([H])([H])C3([H])[H])=C(C([H])=C2C(F)(F)F)[N+]([O-])=O)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1[H])C(=O)O[H]
[H]OC(=O)[C@@]12C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C1([H])[H])[C@]([H])(N([H])C(=O)C(OC1=C([H])C([H])=C([H])C(Cl)=C1[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC2=C1N=C([H])N2[H]
[H]N([H])N1C(=S)N([H])N=C1C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(OC([H])([H])C4=C([H])C(F)=C([H])C([H])=C4[H])C([H])=C3[H])C2=C1[H]
[H]N1C([H])=C(N=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=N1)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C([H])C(=C([H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=O)C(=O)C(C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C1O[H]
[H]N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C([H])C([H])=C3[H])C(=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)N1C2=C3C(=C(Cl)C(OC([H])([H])[H])=C2OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]3([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]2([H])OC(=O)[C@@]3([H])N(C(=O)C(=O)[C@]4(O[H])O[C@@]([H])(C([H])([H])C([H])([H])[C@@]4([H])C([H])([H])[H])C([H])([H])[C@@]([H])(C4=C([H])C([H])=C([H])O4)\C(=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C([H])\[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)[C@]([H])(OC([H])([H])[H])[C@]([H])(O[H])\C(=C([H])\[C@]([H])(C(=O)C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C(Br)=C([H])N=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC1=NC2=C([H])C(Cl)=C(C([H])=C2C(OC([H])([H])C([H])([H])[C@@]2([H])N([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[N+]([O-])=O
[H]N(C1=C([H])C([H])=C([H])N2C(Cl)=C(N=C12)C([H])([H])[H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]O[C@@]1([H])[C@]([H])(F)[C@@]([H])(O[C@]1([H])C([H])([H])O[P@@](=O)(O[H])OP(=O)(O[H])O[H])N1C([H])=C([H])C(=O)N([H])C1=O
[H]N([H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])N2C([H])=C(N=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])=C(C2=C([H])N(C3=C2C([H])=C(F)C([H])=C3[H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(/C([H])([H])N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])S(=O)(=O)C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])C(=O)N([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])\N=C(\S[H])N([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(C#N)=C([H])C(=C2O1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)[C@]([H])(N(C([H])([H])[H])C([H])([H])C1=C([H])C2=C(N=C([H])N=C2C([H])=C1OC([H])([H])[H])N([H])C1=C(F)C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C2=NC(=C([H])S2)C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C#C[H])N([H])C(=O)C([H])([H])[C@]1([H])C(=O)N(C([H])([H])C([H])([H])C2=C([H])C(=NC([H])=C2[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C2=C(S1)S(=O)(=O)[C@]([H])(C([H])([H])[H])C([H])([H])[C@@]2([H])N(C([H])([H])C1=C([H])C(=O)OC2=C1C([H])=C([H])C(Cl)=C2[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=NC([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N([H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(C3=C([H])C([H])=C(O[H])C([H])=C3O[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C(=O)OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])O2
[H]N([H])C1=C([H])C2=C(C3=C([H])C([H])=C([H])C([H])=C3[H])[N+](=C3C([H])=C(N([H])[H])C([H])=C([H])C3=C2C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC(=NC(=O)N1[H])C1=C([H])N([H])C2=NC([H])=C([H])C([H])=C12)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]1([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C1=C(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2N1[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])C(F)(F)F)C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N(C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])O[C@]([H])(C2([H])[H])[C@](O[H])(C2=C([H])C([H])=C([H])C(F)=C2C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[C@@]1([H])N([H])[H]
CCNC(=O)C1=CN2N=CN=C(NC3=C(C)C=CC(=C3)C(=O)NC3=NC=CS3)C2=C1C
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C(=O)N([H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=NN([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C(Cl)=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C2C([H])=C3OC([H])([H])OC3=C([H])C2=NC(\C([H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])[C@@]([H])(OC([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1(OC([H])([H])[C@]2([H])N(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(\C(=N/C#N)N1C([H])([H])C([H])([H])C(=C2C3=C(C([H])=C(Br)C([H])=N3)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(N([H])C(=O)C3=NC(C#N)=C([H])N3[H])C(=C2[H])C2=C([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=NN(C([H])=C2C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2=NC(=C([H])C([H])=C2[H])C(F)(F)F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C(=O)[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])N1C(=O)C(=NC2=C([H])N=C(N=C12)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1C([H])([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])C2([H])[H])C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C(=C(C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC1=NC2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])=C1C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C(O[H])=C(O[H])C([H])=C1[H]
CN1CC[C@@H](C1)OC1=C(C=CC(NCC2=CC=CS2)=C1)C(F)(F)F
[H]OC([H])([H])C([H])([H])OC1=C([H])C([H])=C2OC3(C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C2=C1[H]
[H]O[C@@]1([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])O[C@]([H])(C2([H])[H])[C@](O[H])(C2=C([H])C([H])=C([H])C(Cl)=C2C2=C([H])C(=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[C@@]1([H])N([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])SC1=NN=C(N1C([H])([H])C([H])([H])[H])C([H])([H])N1C(=O)C([H])([H])OC2=C([H])C([H])=C(C([H])=C12)C([H])([H])[H]
[H]N([H])C(=O)C1=C(N([H])C(=C(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C(C3=C([H])C([H])=C([H])C([H])=C3[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C2N(C(=C(C2=C1[H])C([H])([H])C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
O=C1OC(=O)C2=C3C(=CC=C2)C=C(NS(=O)(=O)C2=CC=C(S2)S(=O)(=O)C2=CC=CC=C2)C=C13
[H]N1C([H])=NC(=C1[H])C([H])([H])C1=C(Br)C([H])=C([H])S1
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C(C(=O)N([H])C1=O)C1=NC(=NC([H])=C1C(F)(F)F)N1C([H])([H])C([H])([H])C(=O)C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C(=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N(C1=N\C(=C(\[H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C(=O)N1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O\N=C(/[H])C1=C(F)C([H])=C([H])C(=C1[H])C1=C([H])C(=NC(OC([H])([H])[H])=N1)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=NC2=C1C([H])=C(C([H])=C2C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C2(OC3=C([H])N(N=C3C(=O)C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(SC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C(N=C(Cl)C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])N2C(=O)OC([H])([H])C2([H])[H])C([H])([H])C2=C([H])SC([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])N2C(=NC(=C2C2=NN(C(=O)C([H])([H])C2([H])[H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])=C1[H]
[H]N([H])C1=C(C([H])=C2C(N=C([H])N=C2N2C([H])([H])C([H])([H])N(C(=O)N([H])C3=C([H])C([H])=C(OC4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])C2([H])[H])=C1[H])[N+]([O-])=O
[H]N([H])C([H])([H])[C@](C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl)C1([H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(F)C([H])=C([H])C(F)=C1Cl
[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=NC([H])=C([H])N=C1[H]
[H]OC(=O)C1(N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2N([H])C(=O)N([H])C2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[C@]1([H])OC2=C(F)C([H])=C([H])C([H])=C2OC1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(=O)N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2OC([H])([H])[C@@]3([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])OC([H])([H])[C@]3([H])C2=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])OC1=C2N(C3=C(C2=C([H])C(=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])N([H])[C@]([H])(C([H])([H])C1([H])[H])C3([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C(=C([H])C2=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC(=O)[C@]1([H])N(C(=O)C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CC(C)COC1=CC=C(C=C1N(O)=O)C1=CC(=NO1)C(O)=O
[H]C1=C(C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])N=C(C([H])=C1[H])C([H])([H])N(C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])S(=O)(=O)C1=C(N=C(S1)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]OC(=O)[C@]1([H])N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[C@@]([H])(\N=C(/S[H])N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(OC1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(SC(=N1)[C@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]O[C@]1(C([H])([H])N2C([H])([H])[C@@]([H])(N(C([H])([H])[C@@]2([H])C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])C(=O)[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]23[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=NN=NN1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=NN=C(S1)N1C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H]
[H]N(C1([H])C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N2C(=O)C3=C([H])C(OC4=C([H])C([H])=C([H])C([H])=C4[H])=C([H])C([H])=C3N([H])C(=O)C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]12C(=C([H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2=O)C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C2=NC(=C3C([H])=C(N([H])C(=O)C([H])([H])OC4=C([H])C([H])=C(OC(F)(F)F)C([H])=C4[H])C([H])=C([H])C3=N2)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3N=C(N([H])C3=NC([H])=C2Cl)C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@]1(OC(=O)\C(=C(\[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H])C([H])([H])OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]C1=C([H])N2C(=NC(=C2C2=C([H])C([H])=C(C#N)C([H])=C2[H])[C@]([H])(N(C(=O)C([H])([H])C2=C([H])C(=C(F)C([H])=C2[H])C(F)(F)F)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)C1=C([H])C2=C([H])C(=C([H])C([H])=C2O1)C1=C([H])N(N=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H]
[H]C1=C2C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])[C@@]1([H])N(C([H])([H])C3=C(C([H])=C(C([H])=C3C([H])([H])[H])C([H])([H])[H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N1C([H])([H])C2=C([H])C(I)=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=NN(C(=O)N(C([H])([H])[H])C([H])([H])[H])C(SC([H])([H])[H])=N1
[H]N([H])C1=NC(=NN1C1=NC([H])=C([H])C([H])=C1[H])N([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])S(=O)(=O)C1=C2N=C(C([H])=C(N2N=C1SC([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C(=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C2=C1SC(=C2C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC(C#N)=C([H])C([H])=C1[H]
[H]OC1=C(C(OC([H])([H])[H])=C(C2=C1C(=O)OC2([H])[H])C([H])([H])[H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])N(C([H])=O)C([H])([H])C([H])([H])P(=O)(O[H])O[H]
[H]OC1(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@]2(C#N)C3=C(SC([H])([H])C4=C2C([H])=C([H])C([H])=C4[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C1C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])[H])C([H])=C2[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(/C1=C([H])C([H])=C(Br)C([H])=C1[H])[C@]([H])(N1C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C#N)C([H])([H])C([H])([H])N1C(=O)N(C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(N([H])C(=S)N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC2=C3N(N=C(C(=O)N([H])C4([H])C([H])([H])[C@@]5([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])C5([H])[H])C4([H])[H])C3=C([H])C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1C1=C2C([H])=C([H])C(=O)C([H])=C2OC2=C([H])C(O[H])=C([H])C([H])=C12
[H]C1=C(SC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])C4=C(OC([H])([H])O4)C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C([H])C2=C1N([H])C(=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2N=C(N([H])C2=C1[H])N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(N([H])C2=C1C([H])=C([H])C1=C([H])N=C(\C([H])=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C21)C([H])([H])N([H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])P(=O)(OC([H])([H])[H])OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]N(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(C([H])=C([H])C([H])=C2C2=C1C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H])C([H])([H])[H]
[H]N([H])C1=C2C([H])=C(N([H])C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C2=NC(=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OP(=O)(OC2=C([H])C([H])=C(C([H])=C2[H])C(=O)N([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])[C@]2([H])N(C(=O)[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[N+]3([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H]
[H]N([H])C1=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C2=NC(=N1)N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])OC([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])[C@]([H])(N([H])C2([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(C(=O)N([H])[C@@]([H])(C1=NN=NN1C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)C(=NC2=C([H])N=C(N=C12)N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C(N([H])C(=O)[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]([H])(C(=O)O[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])=C(C3=C([H])C(Cl)=C([H])C([H])=C3Cl)C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C1=NC2=C(OC([H])([H])[H])C([H])=C([H])C(N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])=C2S1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC1=NN=C(O1)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1C([H])([H])N1C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])O1
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])N=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C2=C1N([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(OC1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([O-])=O
[H]N1C(=O)ON=C1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C2=NOC(=O)N2[H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)N([H])C2=C3C(=O)C4=C(N([H])N=C4C3=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C1=NC(=NO1)C([H])([H])N([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])[N+]([O-])=O
[H]N1C(=O)C(C2=C([H])N(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[H])=C(C1=O)C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N([H])C1=C(C#N)C(N([H])[H])=C([H])C(=N1)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N1C(=O)C2=C(C([H])=C([H])C([H])=C2N2C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@]12[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OP(=S)(O[H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C(C3=C(S2)C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C3([H])[H])C(=O)O1
[H]C1=C([H])C(=C([H])C([H])=C1O[C@@]1([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1([H])[H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=NC2=C([H])C([H])=C(C([H])=C2S1)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(N=C(C(=O)N2[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])[H])C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C(=O)N1C([H])([H])C([H])(OC2=C(N=C([H])C([H])=N2)C2=C([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C1=C(Cl)C2=C(N=C1[H])N(N=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC1=C(F)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])N1C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C2([H])[H]
[H]O[C@]1([H])[C@]([H])(O[H])[C@]2(C(=O)N([H])C([H])([H])[H])C([H])([H])[C@]2([H])[C@@]1([H])N1C([H])=NC2=C1N=C(N=C2N([H])C([H])([H])[H])C#CC1=C([H])C([H])=C([H])C(N([H])[H])=C1[H]
[H]OC(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]N1C2=C(N=C1[C@@]1([H])N(C3=NC([H])=NC(=C3[H])N3C([H])([H])C([H])([H])[C@@]([H])(C4=C([H])C([H])=C([H])C([H])=N4)C3([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])=C(Cl)C(Cl)=C2[H]
[H]C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C1=NC2=C([H])C([H])=C(C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C2([H])[H]
[H]C1=C([H])C(OC2=C([H])N=C(C([H])=N2)C2=NN=C(N2C2=C([H])C([H])=C(OC([H])([H])[H])N=C2[H])C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
CS(=O)(=O)CCNC(=O)C1=CC2=C(NCC1)N=CN=C2NC1=CC(Cl)=C(OC2=CC=CC3=C2C=CS3)C=C1
[H]N([H])C(=[N+]([H])[H])C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])C(=C([H])C(=C1[O-])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])[C@]([H])(C([O-])=O)C([H])([H])C([O-])=O
[H]N(C1=C([H])C(Cl)=C([H])C2=C1N([H])C([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C2=C([H])C(OC3=NC([H])=C([H])S3)=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N([H])C1=NC2=C(N=NN2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]ON([H])C([H])([H])C1=C([H])C([H])=C([H])C(N([H])C(=N[H])C([H])([H])[H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N1C([H])([H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C([H])([H])[H])[C@@]([H])(N1C(=O)N(C2=C1C([H])=C(F)C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C2C(=O)N(C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])C2=NC2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C(C2=C(C([H])=C([H])C(C#N)=C2[H])N1C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C(=O)N([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
CC[C@@H]1[Se]C(N)=N[C@@H]1C
[H]OC1=C([H])C([H])=C([H])C2=C([H])C([H])=C(C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C1(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])P(=O)(O[H])O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N([H])[H]
[H]O[C@]1(N2C(=NC([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1F
[H]OC(=O)C([H])([H])N([H])[C@@]([H])(C(=O)N1C([H])([H])OC([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])N=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(N2N=C(N(C(=O)C2=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2O[C@@]([H])(C(=O)N(C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])S(=O)(=O)C3([H])[H])C([H])([H])OC2=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1N=C([H])C(N([H])C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])[H])C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C(=N1)N1C([H])([H])C([H])([H])S[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])[C@]1([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2OC(=O)C1([H])[H]
[H]C1=C([H])C(C2=NC(=C3N2C2=C([H])C(F)=C([H])C(OC([H])(F)F)=C2N=C3C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C(=NO1)C1=C([H])C([H])=C(Cl)S1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OP(=O)(O[H])C([H])(C([H])([H])N1C([H])=NC2=C1N=C([H])N=C2Cl)P(=O)(O[H])O[H]
[H]N(C1=C2N(C([H])=C([H])C2=NC([H])=N1)C([H])([H])C([H])([H])N([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C3=C2C([H])=NS3)C(Cl)=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C#N)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])[C@]2([H])C([H])([H])[H])=C2C(=N1)C(OC2([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N2C(=N1)N=C(C([H])=C2N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1Cl)C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N(N=C1N([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C1=C([H])C([H])=C2N=C([H])N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN=NN1C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NN=C(SC([H])([H])C2=C([H])C([H])=NC([H])=C2[H])N1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(C(=O)N(C2=C([H])C(OC([H])([H])C([H])([H])[H])=C(C([H])=N2)C([H])([H])C([H])([H])[H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)C([H])([H])[C@@]([H])(C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C1\C2=C(C([H])=C([H])C([H])=C2[H])N(C(=O)C2=C(Cl)C([H])=C(C([H])=C2[H])N2N=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C([H])([H])C1(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)[C@]([H])(C1=C([H])C(F)=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(N=C(C([H])=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]([H])(N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])=NC([H])=C2[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C2N(C(=O)C3=C([H])C([H])=C(Cl)C([H])=C3[H])C(=C(C2=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])[C@@]2([H])C([H])=C([H])C([H])=C([H])[C@@]12[H]
[H]N(C(=S)N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC(Cl)=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=NC2=C([H])N=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])N(C(=O)N([H])[C@]2([H])N=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C(C([H])=C([H])C([H])=C3[H])N(C2=O)C([H])([H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=NC2=C(OC(=N2)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])C#CC([H])([H])N1C([H])=NC([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C2=C(N([H])C1=O)C([H])=C([H])C([H])=C2[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C2C(=C1[H])[C@]13C([H])([H])C([H])([H])N(C([H])([H])C4([H])C([H])([H])C([H])([H])C4([H])[H])[C@]([H])(C2([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC1=C([H])C([H])=C2C(=C1[H])[C@]13C([H])([H])C([H])([H])N(C([H])([H])C4([H])C([H])([H])C([H])([H])C4([H])[H])[C@]([H])(C2([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H]
[H]N(C1=NC(=NC2=C([H])C([H])=C(Cl)C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])S(=O)(=O)N([H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(\C([H])=C(/[H])C2=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=NC2=C(N=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C(F)C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]C1=NC2=C([H])C([H])=C(C([H])=C2N=C1[H])C1=C(C(=O)N(N1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC(=O)C1=C([H])C(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])OC1=C(C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C(C2=C([H])C([H])=C([H])C([H])=C2S1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
O=C(NC1=CC=CC=C1)NC1=CC=C(C=C1)C1=CNN=C1
[H]N([H])[C@]([H])(C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1F)C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CCCCCCCCNC(=O)OCC(OC)O[Si](C1=CC=CC=C1)(C1=CC=CC=C1)C(C)(C)C
[H]N([H])C([H])([H])C([H])([H])C1=C([H])N2C3=C1C([H])=C(Cl)C([H])=C3SC([H])([H])C2([H])[H]
[H]N(C1=C2C([H])=C(C([H])=NC2=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])C2=C1[C@@]([H])(N([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1Cl
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])[C@@]1([H])[C@]([H])(Cl)C([H])([H])[C@@]([H])(O[H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])C(N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C1C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C([H])C1=N2
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)N([H])[C@@]2([H])C([H])([H])C3([H])N(C([H])([H])C4=C([H])C([H])=C5C([H])=C(F)C([H])=C([H])C5=C4[H])[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C(C([H])=C([H])C(OC(=O)OC([H])([H])C([H])([H])[H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1(N([H])C(=O)C2=C(O[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@](C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H])(C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=C(N(N=N1)C([H])([H])OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)O[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)C1=C([H])C(=C([H])S1)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N(C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[N@@+]23C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]([H])(OC(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C3([H])[H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2C(O[C@]1([H])C(=O)OC([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(F)=C([H])C(C#N)=C1[H]
[H]O[P@](=O)(C([H])([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=NC(OC2=C([H])C([H])=C([H])C([H])=C2[H])=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])O1
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(S1)C([H])([H])N(C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(=O)O[H]
[H]N(C1=NC2=C(S1)C(=NC([H])=N2)N([H])C1=C([H])C(Cl)=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NC2=C(C(=NN2C2=C(Cl)C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C([H])([H])[H])C(=O)N1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C([H])=C(Cl)C(=C2[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])OC([H])([H])[H]
[H]N1C([H])=NC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])OC([H])=C1[H]
[H]N(C1=C([H])C([H])=C(Cl)N=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3N=C(N([H])C3=NC([H])=C2Cl)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])S1
CNC1=NC(=CC=N1)N1C=CC2=C1C=C(C=C2)C#N
[H]N(C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(N2N=C3C(=C2C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C3=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]N([H])C(=O)C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(N1C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C3=C(N=C2C(F)(F)F)C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1F)S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C1=C(N(N=C1[H])C([H])([H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H])C(F)(F)F
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)C2([H])[H]
[H]N1C(=O)N(C([H])([H])[H])[C@]2(C1=O)C([H])([H])C1=C(C([H])=C3C([H])=C([H])C(=NC3=C1[H])C([H])([H])N1C(=O)N3C4=C1C([H])=C([H])C([H])=C4N([H])C(=O)C3([H])[H])C2([H])[H]
CN1CCN(CC(=O)N2C3=C(C=CC(CO[Si](C)(C)C(C)(C)C)=C3)C(=O)NC3=C2N=CC=C3)CC1
[H]OC1=C([H])C(=NC2=NC(=C([H])C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C(Br)S1
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])C(=O)OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(F)C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
CCCCCN1C=C[N+](CC(P(O)(O)=O)P(O)([O-])=O)=C1
[H]N(C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C1=NC3=C([H])C([H])=C(F)C([H])=C3C(C([O-])=O)=C1C([H])([H])S2
[H]N1C2=C(C([H])=C(Cl)C([H])=C2[H])C2=C1C([H])([H])[C@@]([H])(C2([H])[H])[C@@](F)(C(=O)OC([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])N1C(=C(C(=O)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]\C(=C1\SC(=NC1=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC2=C(N=C([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2N=C(N([H])[H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC(=C(OC([H])([H])C(=O)N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])[N+]([O-])=O
[H]OC(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=NC3=C([H])C([H])=C([H])C([H])=C3S2)C1=O
[H]N(C(=O)C([H])=C1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3C([H])=C(F)C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])[C@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C(C1=O)=C23
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(OP(=O)(OC(=O)C([H])([H])[H])OC(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC([H])([H])[C@]12O[C@@]1([H])[C@@]1([H])[C@@]3([H])O[C@@]4(O[C@@]3(C(=C([H])[H])C([H])([H])[H])[C@]([H])(OC(=O)C(\[H])=C(/[H])\C(\[H])=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])[H])[C@]1(O4)[C@@]1([H])C([H])=C(C(=O)[C@]1(O[H])[C@]2([H])O[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C1=NC2=C(SC(=C2[H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])N2C1=NC([H])=C2C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])C([H])=C(N([H])[H])C(C#N)=C(N([H])[H])[C@@]3([H])C([H])([H])C2=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])[C@]([H])(O[C@]1([H])C([H])([H])OP(=O)(O[H])O[H])N1C([H])=C(Cl)C(=O)N([H])C1=O
[H]N(C1=NC2=C(SC([H])=C2[H])C(=N1)C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=C2C(=NC([H])=N1)N=C(C1=C([H])C([H])=C([H])S1)C(=C2C1=C([H])C([H])=C([H])C(Br)=C1[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N(C([H])([H])C([H])([H])N1C(=O)N(C3=C([H])C(OC(F)(F)F)=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C2([H])[H]
[H]N(C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@@]([H])(C2=C([H])C([H])=C(F)C(F)=C2[H])C1([H])[H]
[H]C1=C(C([H])=C(C([H])=C1C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C1=C2N=C([H])N(\C([H])=C(/[H])C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C2=NC([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])P(=O)(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(N([H])C2=C(N([H])[C@@]([H])(C3=C(Br)C([H])=C([H])O3)C([H])([H])C([H])([H])[H])C(=O)C2=O)C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NN=C(S1)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C4C(ON=C4C([H])([H])[H])=C3[H])C([H])=C2C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]1([H])C(=O)O[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(N([H])C2=NC(=C([H])C([H])=N2)C2=C(N=C(N2[H])C2([H])C([H])([H])C2([H])[H])C2=C([H])C(N([H])C(=O)C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C([H])C([H])=C2[H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC3=C(N2C([H])([H])C#CC([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C(=N2)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])S[C@]2([H])C([H])([H])N([H])[C@]([H])(C(=O)OC([H])([H])[H])C2([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C(=S)OC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])[H]
[H]N(N1C2=C([H])C([H])=C(Cl)C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C(Cl)=C2[H])C(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(C(=NC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[S@](=O)C([H])([H])[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])O1
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C(C(=O)C([H])([H])[H])C(=O)N([H])C1=O
[H]ON([H])C(=N[H])C1=C([H])C2=C(N=C3C4=C([H])C5=C(C(=O)N4C([H])([H])C3=C2C([H])([H])C([H])([H])[H])C([H])([H])OC(=O)[C@]5(O[H])C([H])([H])C([H])([H])[H])C([H])=N1
[H]N(C(=O)C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C1=NS(=O)(=O)C2=C([H])C(F)=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])[C@]2([H])C([H])([H])[C@]2([H])[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])[C@@]([H])(C([H])([H])C2([H])C([H])([H])C2([H])[H])C2([H])C([H])([H])C2([H])[H])[C@]1([H])O[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[N+]([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])C4=C(C([H])=C(C([H])=N4)C4=C([H])C([H])=C(Cl)C([H])=C4Cl)C([H])([H])[C@@]4([H])[C@]5([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N1C(=C(C(=O)OC([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=NC([H])=C1F)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C#N)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(C(=O)C(\[H])=C(/[H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C(=O)N([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)N(C2=C1N=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=NN=C(O2)C2=C([H])C(Cl)=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@@](C#N)(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1I)[C@@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C3N([H])C(=O)C(=O)N([H])C3=C([H])C(=C12)[N+]([O-])=O
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])=C(N=C2C1=C([H])C([H])=C(I)C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])F
[H]C1=NN=C(C([H])=C1[H])C([H])([H])C(=O)C(=O)OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[C@]1([H])OC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)OC([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])S1
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C4C2=C([H])C([H])=C([H])C4=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N2C3=C([H])C([H])=C([H])C([H])=C3C(C(=O)C(F)(F)F)=C2C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(F)(F)F)[C@@]12C([H])([H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])SC1=NN=C(N1C([H])([H])[H])C1=C(N=C(O1)C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)C([H])([H])Cl)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C2=C(OC(=N2)C2=C([H])C(Br)=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])C(=O)O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1\C(=N/C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)N(C(=O)SC([H])([H])[H])C([H])([H])C2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
CNC(=O)CC1=CC(=O)OC2=CC(OS(=O)(=O)C3=CC=CC(Cl)=C3)=CC=C12
[H]O[C@@]1([H])[C@@]([H])(O[C@]2(C([H])([H])C2([H])[H])[C@@]1([H])O[H])N1C([H])=C(I)C2=C(N=C([H])N=C12)N([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(I)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(Br)C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C(=O)N([H])[C@@]2([H])C([H])([H])C([H])([H])S(=O)(=O)C2([H])[H])C2=C(S1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
Cl[H].[H][C@]12CNC[C@]1([H])C1=CC(=CC(C)=C1C(=O)N2)C1CC1
CCCCN1C(C)=C(C)C=C(NC(=O)C2=C(C)C=CC=C2)C1=O
[H]C1=C([H])C(=C([H])C([H])=C1Cl)S(=O)(=O)C1(C(=O)N2C([H])([H])C([H])([H])N(C3=C(C([H])=C([H])C(Cl)=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(SN=C2C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N=C1C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])([H])C(=O)N([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])N(C(=O)C11C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]([H])(\N=C(/S[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])[C@]([H])(O[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C(=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C1=NN([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C([H])=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])C2=C1[H]
[H]N(C1=NC(=O)C2(O1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C(Cl)=C2[H])C(=O)N1C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])[C@]1([H])ON=C(C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=O)N(C(=NC2=C1[H])C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])C([H])=O)[C@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2N=C([H])N(C2=NC([H])=N1)[C@]1([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]1([H])O[H]
CC(=O)NC1=C(OC[C@@H](O)CN2CCC3(CC4=CC(Cl)=CC=C4O3)CC2)C=C(O)C=C1
[H]N(C1=NC([H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])N=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=C(Br)C(=N1)N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C2N([H])C([H])=NC2=C1[H]
[H]OP(=O)(O[H])C([H])(SC1=NC([H])=C([H])S1)P(=O)(O[H])O[H]
[H]OC(=O)C([H])([H])N1C(=O)[C@]([H])(N([H])[C@@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C2O[C@]3(C4=C(C5=C(N4[H])C([H])=C([H])C([H])=C5[H])C([H])([H])[C@@]4(OC([H])([H])C([H])([H])[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N([H])C1=NN([H])C([H])=C1C(=O)N1C([H])([H])[C@@]2([H])C([H])([H])N(C(=O)C([H])([H])N3C(=O)[C@@]([H])(N([H])S(=O)(=O)C4=C([H])C5=C([H])C([H])=C(Cl)C([H])=C5C([H])=C4[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]([H])(C1([H])[H])C2([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]C1=NC2=C(C(=NO2)C([H])([H])[H])C(SC2=C([H])C([H])=C([H])C([H])=C2Cl)=N1
[H]ON([H])C(=O)[C@@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2N(C(=O)C2([H])C([H])([H])C2([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(N1C([H])([H])[H])C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1Cl)C1=C([H])C(C#N)=C([H])C(=C1[H])C([H])([H])N1N=C([H])N=C1[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)N(C2=C1N=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=NN=C(O2)C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])C1([H])[H]
[H]N1N=C(N(\N=C(/[H])\C(\[H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[N+]([O-])=O)C1=S)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])N1C([H])([H])C(=O)N(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])N3C([H])([H])C([H])([H])C([H])([H])S3(=O)=O)C([H])([H])C2([H])[H])=C2C([H])=C([H])C(=NC2=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C(=N[H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])N=C([H])C([H])=N2)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=O)C1=C(Cl)C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C1=C(C(=O)N([H])C1=O)C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N3C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C2([H])C2=C([H])C(O[H])=C([H])C([H])([H])[C@@]12[H]
[H]N(C([H])([H])C1=NC(=C([H])N=C1[H])C1=C(F)C(F)=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(\N=C1/C(=O)N([H])N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(S1)N(C([H])([H])C1=C([H])C2=C(N=C(N([H])C2=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)O[H]
[H]C#CC([H])([H])N(C([H])([H])C([H])([H])F)[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=NN2[C@@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C(C2=NC3=C(C([H])=C(F)C([H])=C3[H])N2C([H])([H])[H])=C1C([H])([H])[H]
[H]O\N=C(/C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)N1C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])C([H])([H])C([H])([H])C([H])=C=C([H])[H])C([H])=C2C(=NC([H])=NC2=C1[H])N([H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]N(C1=C([H])C2=C([H])C([H])=C([H])C(\C([H])=C(/[H])C3=NC4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C4C([H])=C3[H])=C2C([H])=C1[H])S(=O)(=O)C(F)(F)F
[H]OC(=O)C([H])([H])[C@@]([H])(C1=C([H])N=C(S1)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=NC(=NO1)C([H])([H])C([H])([H])C([H])([H])C1=NC2=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N2[H]
[H]N(C(=O)OC([H])([H])[C@@]([H])(OC([H])([H])[H])C([H])([H])OC(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=NC([H])=C(C2=C1N(C(=N2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])([H])[H]
[H]N1C(=O)C([H])([H])C([H])([H])C2=C1N=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C4OC([H])([H])C([H])([H])C([H])([H])C4=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])=C2[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=C2[H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)[C@@]([H])(C([H])([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C1=NC(=C([H])S1)C([H])([H])C1=NN=C(SC([H])([H])C(=O)OC([H])([H])[H])N1N([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2OC([H])([H])[H])C([H])([H])C2=NC([H])=C(S2)C2=C([H])OC([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])C1=NC(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])C([H])(C(=N/OC([H])([H])C([H])([H])[H])\C4=C([H])C([H])=C(Br)C([H])=C4[H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])C(=O)C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H]
[H]N(\N=C1/C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12)C(=O)C([H])([H])N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])[C@]1([H])N(C(=O)C2=C([H])N(C(=N2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3N=C2[H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1SC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C(=O)N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])SC(C(=O)N([H])C3=C(C([H])=C(Cl)C([H])=C3OC([H])([H])[H])C(=O)N([H])C3=NC([H])=C(Cl)C([H])=C3[H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]N1C2=C(N=C1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=S)N(C(=S)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC([H])([H])C([H])([H])N1N=NN=C1[C@]([H])(N([H])C(=O)C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N(C([H])([H])C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]23[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C([H])S2)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C(Cl)N=C(N([H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C(=O)N1C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])[H]
COC1=CC2=C(CN(C[C@]3(NC(=O)NC3=O)C#CC3=CC4=C(C=C3)N(CCN(C)C)N=C4N)C2=O)C=C1
[H]N([H])C1=N[C@@](C(=O)N1C([H])([H])[H])(C1=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N([H])[C@@]1([H])[C@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
CC1(C)C[C@@H](C2=C1NN=C2)C1=CC=C(C=C1)C#N
[H]N(C1=NC(=C([H])C([H])=N1)C1=C(N=C([H])N1C([H])([H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C(Cl)C([H])=C1C1=NN([H])C(C(=O)N([H])C([H])([H])C([H])([H])[H])=C1C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(C([H])([H])C([H])=C([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=NN=C1SC([H])([H])N1C(=O)C2=C(C([H])=C([H])C([H])=C2S1(=O)=O)C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C(N(C3=C([H])C([H])=C(Cl)C([H])=C23)C([H])([H])[H])C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(C#N)C2=C([H])C([H])=C([H])C(F)=C2C(SC([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])=N1
[H]OC([H])([H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(\C1=C([H])C([H])=C([H])C([H])=C1[H])=C1\C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1C1=C2C([H])=C([H])C(=O)C([H])=C2OC2=C([H])C(O[H])=C([H])C([H])=C12)C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])O[P@](=O)(O[H])N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C(=O)O[H]
[H]N(C1=C([H])C([H])=C2N([H])C(=O)OC(C2=C1[H])(C([H])([H])[H])C([H])([H])[H])C1=C(Cl)C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(N([H])C(=O)C(\[H])=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])N(C2=C([H])C3=C(C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C([H])C(N([H])C(=O)C2=C([H])C(=C([H])C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=NN=C1[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])S2)C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]1([H])N(C(=O)C([H])([H])C([H])([H])S[H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(\[H])=C1/C(=O)N([H])C(=O)C2=C([H])C([H])=C(C([H])=C12)C1=C([H])SC([H])=C1[H]
[H]ON([H])C(=O)[C@@]([H])(O[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=NOC(=C1[H])C([H])([H])[H]
[H]N1N=NN=C1C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]2([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
CNC(=O)C1=C(NC(C)C)C2=C(C=C(C=C2)C2=CC=C(C=C2)S(C)(=O)=O)N=N1
CN(C1=NC=CC=C1CNC1=C2C=C(NC2=NC=C1C#N)C1CCCCC1)S(C)(=O)=O
[H]N(C(=O)C1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C(Cl)C(=C2Cl)C([H])([H])OC2=C3N=C(C([H])=C(N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=S)N([H])C1=C([H])C(F)=C(OC2=C([H])C([H])=NC3=C2SC([H])=C3[H])C([H])=C1[H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C1=NC(=NO1)[C@@]1([H])N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])(C2=NN([H])N=N2)C([H])([H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(=C1F)C(F)(F)F
[H]OC(=O)C1=C([H])N=C2C([H])=C([H])N(C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[N+]([O-])=O
[H]C1=NC(=NC([H])=C1[H])C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(Cl)=C([H])OC3=C([H])C([H])=C([H])C([H])=C3C2=O)C1([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C2/OC(=O)N(C2=O)C2=C([H])N=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1Br
[H]N(C(=O)OC1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]1(OC(=O)\C(=C(/[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H])C([H])([H])OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C1OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C#N
COC1=CC=C(CNCCCC[C@@H](NC2=CC(C)=C(F)C(C)=C2)C(=O)NO)C=C1
[H]OC1=C(Cl)C([H])=C(\C([H])=C2/S\C(=N/C([H])(C([H])([H])[H])C([H])([H])[H])N(C2=O)C2=C([H])C([H])=C([H])C(Cl)=C2C([H])([H])[H])C([H])=C1[H]
OC(=O)CCC1=NC(=NC(=C1)C1=CC(=CC=C1)C(F)(F)F)C#N
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])([H])[C@@]3([H])C([H])([H])[C@]2([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C([H])C(O[C@@]2([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C([H])=C1C1=C2C([H])=C(N([H])C2=NC([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(OC1=C([H])C([H])=C([H])C(OC2=C(N(C3=NOC4=C3C([H])=C([H])C(Cl)=C4[H])C3=C([H])C([H])=C(OC(F)(F)F)C([H])=C23)C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C(Cl)C(=C(Cl)C([H])=C1[H])C([H])([H])OC1=C2N=C(C([H])=C(C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=NC(N2C([H])([H])C([H])([H])N(C(=O)N([H])C3=C([H])C([H])=C(C([H])=C3[H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])=C1\C([H])=N\OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=C(SC2=C([H])C([H])=C(OC([H])([H])C([H])([H])F)C([H])=C2C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(N=C(C([H])=C2N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])N(C2=C([H])C([H])=C(OC([H])([H])[H])N=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])[C@@]3(O[C@]12C([H])([H])C3([H])[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(\C(=N\C#N)N([H])C2=C3C([H])=C([H])C(=NC3=C([H])C([H])=C2[H])C([H])([H])[H])[C@@]([H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C(C([H])=C(C2=C1OC(C([H])([H])[H])(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])C(=C([H])[C@@]21[H])C([H])([H])[H])[S@](=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C1=NC(N([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C2N=C([H])N(C2=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]SC([H])([H])C([H])([H])C(\[H])=C(/[H])[C@@]1([H])OC(=O)[C@@]([H])(N([H])C(=O)\C(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C(=O)C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])S[H])=C(/[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C(C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C2=NOC(=C2C(=O)N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C(F)=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C(I)=C1[H]
[H]N([H])C(=O)C1=C(O[C@@]([H])(C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C(S1)N1C([H])=NC2=C1C([H])=C([H])C(=C2[H])C1=C([H])C(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@](C1=C([H])C(Cl)=C([H])C([H])=C1[H])(C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC([H])([H])[H])[C@@]1([H])C([H])([H])N(C(=O)N([H])[C@]([H])(C([H])([H])N([H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(C([H])=C(N([H])C2=C([H])C(=C(N([H])C3=NC(=NC(Cl)=N3)N([H])C3=C(C([H])=C([H])C([H])=C3[H])S([O-])(=O)=O)C([H])=C2[H])S([O-])(=O)=O)C2=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1C2=O)S([O-])(=O)=O
[H]N(C(=O)C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=NN=C(S1)C(F)(F)F
[H]N(C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C2=NC3=C(C(F)=C([H])C([H])=C3N2[H])C([H])([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])N(C(=O)C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])[C@]3(C4=C(C(OC([H])([H])[H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C3([H])[H])C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
CC1=CC=C(C=C1C(=O)NCC1=CC=NC=C1)N1N=C(C=C1NC(=O)NC1=C2C=CC=CC2=CC=C1)C(C)(C)C
[H]N1C(=C([H])C2=C1C(Cl)=C([H])C(=C2[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=N/C#N)\N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]N(C(=O)C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C(C2=C([H])C3=C([H])C([H])=C(O[H])C(=C3O2)C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C(C(O[H])=C1[H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1(O[H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@@]2([H])[C@@]3([H])C([H])([H])C([H])([H])C4=C([H])C(=O)C([H])=C([H])[C@]4(C([H])([H])[H])[C@@]3(F)[C@@]([H])(O[H])C([H])([H])[C@]12C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2(C3=C([H])C(F)=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C(=O)C3=C([H])C(=C(F)C([H])=C3Cl)S(=O)(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C(OC2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(OC([H])([H])C([H])([H])OC2=NC([H])=C([H])C(OC([H])([H])[H])=N2)=NC([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N([H])C([H])([H])C1=C(N2N=C(C([H])=C2N=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)[C@@]([H])(C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2[C@@]([H])(N(C(=O)C2=C([H])C(=C([H])C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C3([H])[H])C1([H])[H]
[H]OC1=C(N([H])C2=C(N([H])[C@@]([H])(C3=C([H])C([H])=C([H])O3)[C@@]([H])(F)C([H])([H])[H])C(=O)C2=O)C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(C([H])=C1C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C(=O)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C2ON=C(C2=C1[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
C[C@@H](O)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](CCCCN)NC(=O)[C@H](CC1=CNc2ccccc12)NC(=O)C(Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H](N)Cc1ccc2ccccc2c1)C(C)O)C(C)O)C(N)=O
[H]N(C1=NC(=NC2=C([H])C([H])=C(Cl)C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C(C([H])=C([H])S1)C([H])([H])[H]
[H]N(C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]C1=NN(C2=C1C([H])([H])[C@]1(C(=C2[H])C([H])([H])C([H])([H])N(C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C(OC(F)(F)F)=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(F)=C([H])C([H])=C([H])C2=NC2=C1[C@]1([H])C([H])([H])C(=C([H])[C@]([H])(C2([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C1=NN=NN1C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N(C1=NC([H])=NC2=C1C([H])=C([H])C([H])=C2[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])S1)C1=NC([H])=C(Br)C([H])=C1[H]
[H]N([H])C([H])([H])C1=C(N2C([H])=C(N=C2N=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\[H])N([H])C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)N([H])[H])C2=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(=C(Cl)C(Cl)=C1N([H])C(=O)C([H])([H])N([H])C([H])([H])[H])S(=O)(=O)N([H])[H]
[H]N(C(=O)OC1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)OC1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C1=NC(=C(N1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=NC2=C([H])C([H])=C([H])N=C2C([H])=C1[H]
[H]N(C1=C([H])C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C4([H])[H])=C(OC([H])([H])[H])C([H])=C23)=C(F)C([H])=C1[H])S(=O)(=O)C1=C([H])C(F)=C([H])C([H])=C1F
[H]\C(C1=C([H])SC([H])=C1[H])=C1\C([H])([H])N2[C@]3([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]1([H])C3([H])[H]
[H]N([H])C1=NC(=NC(=N1)C1=C(N=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])C([H])([H])[H]
[H]N1C(=C([H])C2=C([H])C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C12)C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C(C([H])([H])N2N=C([H])N=C2[H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(\C#N)=C1/C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])OC([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]2([H])C([H])([H])N(C([H])([H])[C@]2([H])C1([H])[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC([H])([H])C(=O)C(F)(F)F
[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])S2)C([H])([H])C1([H])[H]
[H]C1=NC2=C([H])C([H])=C(C([H])=C2N=C1[H])C1=C(C(=O)N(N1C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])[H]
C[N]12CCC3=CC(OCCCCCCCCCCCCOC4=CC=C5C6C7=C(CC[N]6(C)CCC5=C4)C=CC=C7)=CC=C3C1C1=C(CC2)C=CC=C1
[H]OC1=C(C2=C([H])C([H])=C(F)C([H])=C2[H])C(=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O)C(=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC(=O)[C@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])OC([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(OC2=C(C([H])=C([H])C(OC3=C(C([H])=C([H])C([H])=C3[H])C(=N[H])N([H])[H])=C2[H])[N+]([O-])=O)=C([H])C([H])=C1[H]
[H]N1C(=O)C2=C(C1=O)C1=C(C([H])=C([H])C3=C1N(C([H])=C3[H])C([H])([H])[H])C1=C2C2=C(N1[H])C(Br)=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C2=C3N1C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C2[H])C([H])([H])C([H])=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C2=C([H])C(Br)=C(F)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C(=O)C2=C(O[H])C([H])=C(C([H])=C2O[H])C(=O)OC([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])N([H])C(=O)C2=C([H])C([H])=C(O[H])C([H])=C2[H])C(O[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=NC3=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C([H])=C3C(N([H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C([H])([H])N([H])C3=C4C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N5C([H])([H])C([H])([H])C([H])([H])C5([H])[H])=C([H])C4=NC4=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N5C([H])([H])C([H])([H])C([H])([H])C5([H])[H])=C([H])C([H])=C34)=C2C([H])=C1[H]
[H]C1=C(N=C(S1)C1=C([H])C2=C(OC1=O)C([H])=C(C([H])=C2[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C(F)=C([H])C(F)=C2O[C@@]1([H])[C@]1([H])C([H])=C([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C3=C([H])C([H])=C([H])C(=C3[H])S(=O)(=O)C([H])([H])[H])[C@@]12[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])[H])[C@]1(C2=C([H])C([H])=C(F)C([H])=N2)C([H])([H])C2([H])N(C([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C(Cl)C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N1C2=C(N=C1[C@@]1([H])C([H])([H])C([H])([H])[C@]3(OC(=O)C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C1([H])[H])C([H])=C(Cl)C(=C2[H])C(F)(F)F
[H]N1C([H])=NC2=C1C([H])([H])[C@]([H])(C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C1=NC([H])=C([H])C(=C1[H])C1=NN(C([H])=C1C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(N=C1C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C(=O)N1C([H])([H])C([H])(OC2=C(C([H])=C([H])C([H])=N2)[C@@]2([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C1=C(F)C([H])=C([H])C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C4=C(C([H])=C3[H])C([H])([H])C([H])([H])C(=O)N4[H])C([H])([H])C2([H])[H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])[C@@]1([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
CC(C)CC1=CC=C(C=C1)C(C)C(=O)OCCNS(=O)(=O)C1=CC=CC2=C(C=CC=C12)N(C)C
[H]C1=C([H])C([H])=C(C2=NOC(=N2)C([H])([H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C3=C(C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]O\C(=C(\C#N)/C(=N\[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])/N([H])C1=C([H])C2=C(OC(=C2[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1N=NC(=N1)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H]
CC1=CC(=CC=C1F)C(=O)NCCCC[C@@H](NC1=CC(C)=C(F)C(C)=C1)C(=O)NO
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(O[H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(\C(=N\C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[C@]([H])(C1=C(N([H])C2=C1C([H])=C(S2)C(C(=O)N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
CN1N=NN=C1C1=CC2=C(SC3=C(CC2N2CCN(C)CC2)C=CC=C3)C=C1
[H]N(C(=O)C(N([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C1=NN2C(=C([H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])=N1)C1=C([H])C(F)=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C(C([H])=C(Cl)C(N([H])[H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(C#N)(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])=C([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C(C(=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])N1C([H])([H])C2=C(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3OC2=O)C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(C([H])=C(F)C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(S[C@]([H])(C2=C(N=C(S2)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])[H])C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2F)C([H])=C1C([H])([H])[H]
COC1=C2N=C(NC(=O)C2=CC(=C1)C1=CNN=C1)C(N)C1=CC=CC(Cl)=C1
[H]N1C(=O)C2=C([H])C([H])=C(C([H])=C2C1=O)N1C(=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]N(C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])[C@]([H])(C#CC1=C([H])N=C(OC2=C([H])C([H])=C([H])C(OC3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2[H])S1)C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])([S@](=O)C([H])([H])[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C(C([H])=C2N1S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(N=C(N1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1Cl)C([H])([H])[H])C1=C([H])C(F)=C(F)C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])N([H])C(=O)C([H])([H])SC1=NC2=C(C3=C(S2)C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N1C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=N1
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]O[C@]12C([H])([H])C3=C(O[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1(O[H])[C@@](C([H])=C([H])C(=O)[C@]21C([H])([H])[H])(C([H])([H])[H])C([H])([H])I)C([H])=C(OC3=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(\[H])=C1/C(=O)N([H])C(=O)C2=C([H])C([H])=C([H])C(Br)=C12
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=N1)N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C1([H])[H])S2(=O)=O
[H]N1N=C(C2=C1C(=C([H])C(=C2[H])C([H])([H])[C@]([H])(OC(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])[H])C([H])([H])N([H])C2=C(F)C([H])=C([H])C(=C2[H])C([H])([H])[H])=N1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C2OC(=C([H])C(=O)C2=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([C@]1([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2C1([H])[H])C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])N1C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])S1
[H]N([H])S(=O)(=O)C1=C([H])C(Cl)=C(N([H])C(=O)C([H])([H])N([H])C([H])([H])[H])C([H])=C1[H]
[H]C([H])([H])[N+]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]2(ON=C(Br)C2([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])C2([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
Cc1cnc(N[C@H]2C[C@H]2CO)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])O[N+]([O-])=O)C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])[C@@]1([H])N(C(=O)C2=C([H])N(C(=N2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3N=C2[H])C1([H])[H]
[H]N1C2=C([H])C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2C2=C1C(=NC([H])=C2[H])C([H])([H])[H]
[H]O[C@@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])N3C([H])([H])C([H])([H])C([H])(F)C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C(Br)C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C1=C(OC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=NN(C(=O)C(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1F
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C(=C(SC3=C([H])C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C34)N2[H])C([H])([H])[H])C(=N1)N([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])\N=C(/[H])C2=C([H])N(N=C2C2=C([H])C([H])=C([H])S2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C(C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])C([H])([H])C(=O)[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(I)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])SC(=O)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C3=C(SC(=N3)C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(\N=C(\C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H]
[H]C#CC([H])([H])N1C(=O)N(C2=C(N(C(=N2)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C1=O)C([H])([H])[H]
[H]O[C@]([H])(C(\[H])=C(/[H])N1C(=C([H])C(=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C(F)=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(N=C(C([H])=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(N=C1[C@@]1([H])N([H])[C@]([H])(C2=C(C3=C([H])C([H])=C([H])C([H])=C3N2[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=CC=C2C(SC3=C2N=CN=C3NC2=CC=C(F)C=C2F)=C1
[H]C1=C([H])C(=C([H])C([H])=C1F)C1(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C3(N([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])S1
[H]OC1=C([H])C([H])=C(C([H])=C1I)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])[H]
[H]S\C(=N/C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C(ON=C1[H])C([H])([H])[H]
[H]C1=NC(=C([H])N1C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])N(N=N1)C([H])([H])C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(N([H])C(=S)N2N=C(C(=C2[H])C2=C([H])N3N=C(N=C3C([H])=C2[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])=C1[H]
[H]N(C(=O)N1C([H])([H])C2=C(N=C(N=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]1(O[H])C2=C(OC([H])([H])C1([H])[H])C([H])=C([H])C(F)=C2[H]
[H]OC1=C([H])C([H])=C(C([H])=C1Cl)C1=C(C#N)C([H])=C([H])C(=C1[H])C([H])([H])N1N=C([H])N=C1[H]
CC1=CC2=C(N1)C=CC(NC(=O)C1CCCCC1)=C2
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C1=NC3=C([H])C([H])=C(Br)C([H])=C3C(=O)N1C([H])([H])C2([H])[H]
[H]OC(=O)[C@]1([H])[C@@]([H])(SC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C(=O)N([H])C(C1=O)(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])OC3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])N1N=C(C2=C([H])C([H])=C(C(F)=C12)C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C2=O)C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C(=C([H])C([H])=C2[H])C(=O)N([H])C([H])([H])[H])C([H])=C1[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1O[C@@]1([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(SC2=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(=C2C(F)(F)F)C(F)(F)F)=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])N(C([H])([H])[C@]1([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]N([H])C([H])([H])C1=C(N2C([H])=C(N=C2N=C1C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
CCC(N(CCCN(C)C)C(=O)C1=CC=C(Br)C=C1)C1=NC2=C(C=CC=C2)N1CC1=CC=CC=C1
[H]OC1=C([H])C([H])=C(N([H])C(=O)[C@]2([H])C([H])([H])C([H])([H])[C@]3([H])[C@]4([H])C([H])([H])C([H])([H])[C@]5([H])N([H])C(=O)C([H])=C([H])[C@]5(C([H])([H])[H])[C@@]4([H])C([H])([H])C([H])([H])[C@]23C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[C@]1([H])OC([H])([H])C([H])([H])N(C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]12C([H])([H])[C@]1([H])[C@]([H])(N1C([H])=NC3=C1N=C(Cl)N=C3N([H])C([H])([H])C1=C([H])C([H])=C([H])C(I)=C1[H])[C@@]([H])(O[H])[C@]2([H])O[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C(C([H])=C2[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])N=C(OC2([H])[H])C2=C([H])C(Br)=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C#N)[C@@]1([H])C2=NC([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C(Br)=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C(O[C@@]([H])(C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])[H])C([H])=C(S1)N1C([H])=NC2=C1C([H])=C(C([H])=C2[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(C2=C([H])N([H])C3=C(Br)C([H])=C([H])C([H])=C23)=C(C([H])=N1)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(=NN1[H])C1=C([H])C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C([H])N2N=C(N=C12)C1=C([H])C([H])=C([H])O1)C1=C([H])C(N([H])C(=O)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1(C(=O)N([H])C(=O)N([H])C1=O)C([H])([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])S2)C([H])([H])C1([H])[H]
[H]N1[C@@]2([H])C([H])([H])[C@]1([H])C([H])([H])N(C1=NN=C(Cl)C([H])=C1[H])C2([H])[H]
[H]N1C(=O)N(C([H])([H])C1(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])[N@@+](C([H])([H])[H])(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
COC(=O)C1=CC2=C(NCC1)N=CN=C2NC1=CC(Cl)=C(OC2=CC=CC3=C2C=CS3)C=C1
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H]
[H]\C(=C(\[H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(N=C(O2)C([H])([H])SC2=NC3=C([H])C([H])=C([H])C([H])=C3C3=NC(=NN23)C([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C(=C([H])C([H])=C2N=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N(C(=O)N2[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(SC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2N1C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C2N=C(N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)OC([H])([H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)[C@]2([H])C([H])=C([H])C([H])([H])N3N2C(=O)N(C3=O)[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])SC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=C([H])C2=C1C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C2N=C([H])C([H])=C([H])C2=C(C(=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[N+]([O-])=O
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])N=C(O2)C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C2N=C(C([H])=NC2=N1)C([H])([H])C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)C2=C(C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C1=O
[H]N1C([H])([H])[C@]([H])(F)[C@]([H])(C([H])([H])N(C(=O)N2C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])[C@@]([H])(C2=NC(=NN2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(F)C([H])=C([H])C(F)=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N([H])C(=O)C1=C(N([H])C2=C([H])N=C([H])C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2N=C1[H])S(=O)(=O)C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C(F)(F)F
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C2N=C([H])C([H])=C([H])C2=C1[H]
[H]N(C(=O)N([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])C1=C([H])OC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])C([H])([H])N1N=NN=C1C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N([H])[C@]1([H])C([H])([H])N(C2=C(C#N)C3=C(N2C([H])([H])C#CC([H])([H])[H])C(=O)N(C([H])=N3)C([H])([H])C2=NC([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C1([H])[H]
[H]N(\C([H])=C(/[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC1=C([H])C([H])=C(C([H])=C1C(=O)N([H])C([H])([H])N([H])[C@@]1([H])C([H])([H])[C@]([H])(O[C@]2([H])C3=C(O[H])C4=C(C(=O)C5=C(C4=O)C(OC([H])([H])[H])=C([H])C([H])=C5[H])C(O[H])=C3C([H])([H])[C@@](O[H])(C(=O)C([H])([H])O[H])C2([H])[H])O[C@@]([H])(C([H])([H])[H])[C@@]1([H])O[H])C([H])([H])OC([H])([H])C#CC([H])([H])N1C(=O)N(C(=O)C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C#N)C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(N([H])C2=C([H])C([H])=NC([H])=N2)C([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N1C(=NN=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC1=C(C#N)C([H])=C([H])C(OC([H])([H])C2=C(C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC(=O)C1=C(C2=C(N1[H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C(=O)O[H]
[H]N([H])C1=NC2=C(OC3=C([H])C([H])=C([H])C([H])=C23)C(=N1)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(S1)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC([H])=C(S1)N([H])C([H])([H])C1=C([H])C2=C(N=C(N([H])C2=O)C([H])([H])[H])C([H])=C1[H])C(=O)O[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C(N([H])C2=NC([H])=C([H])C(=N2)N(C2=C([H])C(Cl)=C([H])C([H])=C2Cl)C([H])([H])C([H])([H])C#N)C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(O[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(=C([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])O[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=NN(N=N1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(O1)C([H])([H])[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N(C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C2=C(OC(F)(F)F)C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC2=C1C(=O)N(C(=O)N2C1=C(C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C(C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
FC(F)(F)OC1=CC=C(NC(=O)NC2CCN(CC2)C(=O)C(F)(F)F)C=C1
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(OC1=C([H])C(OC([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])=C([H])C([H])=C1C#N)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]O[C@](C([H])([H])C1=C([H])C2=C(N1[H])C([H])=C(C([H])=C2[H])C([H])([H])[H])(C([H])([H])C(C1=C(OC([H])([H])[H])C([H])=C([H])C(F)=C1[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC1=C(OC([H])([H])[H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])N2C(=O)C3=C(ON=C3C3=C2C([H])=C([H])C([H])=C3Cl)C([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(OC([H])([H])C([H])([H])[C@@]2(OC3=C(C(=C(O[H])C(=C3C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
FC(F)(F)C1=CC=CC(=C1)C1=CC(CCCN2CCOCC2)=NC(=N1)C#N
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)[C@]([H])(C([H])([H])[H])C2([H])[H]
[H]N([H])C1=NC2=C(N=NN2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2F)C(=N1)C1=NC([H])=C(S1)C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1OC([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C3=C(C([H])=C(O[H])C(OC([H])([H])[H])=C3[H])[C@]1([H])C2([H])[H]
[H]O[C@]([H])(C(\[H])=C(/[H])N1C(=C([H])C(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]N1C(=O)C([H])=C(C2=C1C([H])=C([H])C1=C2OC([H])([H])[C@]([H])(N1C([H])([H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)C([H])([H])SC1=C(Cl)C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N([H])[C@]([H])(C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@]1([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])[C@@]([H])(N([H])[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C2N=C([H])C([H])=C([H])C2=C([H])C(OC([H])([H])[H])=C1[H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])[N+]([O-])=O
[H]\C(=C1\S\C(=N/C([H])([H])C([H])([H])OC([H])([H])[H])N(C1=O)C([H])([H])[H])C1=C(N(C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])[H]
CS(=O)(=O)C1=NC(=C(N1)C1=CC=C(C=C1)S(C)(=O)=O)C1=CC=C(F)C=C1
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N2C([H])=C(C3=C([H])C([H])=C([H])C([H])=C23)S(=O)(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])N=C23)C1([H])[H]
[H]OC1=C2C([H])=C(N(C2=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=N[H])N([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O\N=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C3C(=C([H])C(=O)C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]2([H])[C@]2([H])C([H])([H])C([H])([H])[C@@](OC([H])([H])[H])(C([H])([H])OC([H])([H])[H])[C@@]2(C([H])([H])[H])C1([H])[H]
[H]N(C1=C(C([H])=C([H])S1)C1=NC2=C([H])C([H])=C([H])C([H])=C2S1)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C(N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=NC2=C([H])C([H])=C(C([H])=C2N2C([H])=NC([H])=C12)N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C(F)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@@]([H])(N([H])C(=O)C1=NC(=C([H])N=C1N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N(N=C1[H])C([H])([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N(C(=O)C([H])(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(C(=O)O[H])[C@@]([H])(C2=C(Cl)C([H])=C([H])C([H])=C2[H])C(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])=C(N1C([H])([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C(=NN1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C#N
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1=C2OC(=NC2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C2N(C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)C2=C(C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])[C@]2(C([H])([H])N(C3=C([H])C(F)=C([H])C([H])=C3[H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N([C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(C([H])=N3)C(F)(F)F)C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=NC3=C(C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C3[H])C(N([H])C3=C([H])C(SC([H])([H])[H])=C([H])C([H])=C3[H])=C2C([H])=C1[H]
[H]OC1=NC2=C([H])C3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C(=O)N4C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C4([H])[H])=C([H])C([H])=C3N([H])C2=N1
[H]N1N=NN=C1C1=C([H])C2=C(OC3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=NC([H])=C2S1
[H]N([H])C1=NC(N([H])C2=C([H])C([H])=C([H])C(=C2[H])C(=O)C([H])([H])C([H])([H])[H])=C2N=C([H])N([H])C2=N1
[H]OC1=C([H])C([H])=C([H])N(C1=O)C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C(C(=O)C([H])([H])C([H])([H])[H])=C2OC1=O
[H]N([H])C1=C(N=C2C([H])=C([H])C([H])=C([H])C2=C1C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])OC3=C([H])C([H])=C([H])C([H])=C3OC2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
FC1=CC=CC(=C1)S(=O)(=O)NC1(CCC1)C1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
[H]OC(=O)C(\[H])=C(\C(\[H])=C(/[H])\C(\[H])=C(\C1=C([H])C2=C(SC([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])/C([H])([H])[H]
[H]N([C@]([H])(C(=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C([H])N=C12)N([H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]O[C@@]1([H])C2=C(OC(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C1=C([H])C(N([H])S(=O)(=O)C(F)(F)F)=C([H])C([H])=C1OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])C1=C([H])C([H])=C3C([H])=C([H])C(Cl)=C([H])C3=N1)=C2[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C2(N(C(=O)N(C2=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C(=O)OC([H])([H])[H]
[H]N(C1=NC(=NC(=N1)C#N)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C3=C2C([H])=C([H])N3[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=N[C@@]([H])(C#CC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C1SC([H])=C2[H]
[H]C1=C([H])C([H])=C(C(Br)=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])OC2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C(O[H])C(=C(C(O[H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=NC([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1[H])C(=O)C1=C(F)C([H])=C([H])C([H])=C1F
[H]N([H])C([H])([H])C([H])([H])C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N1C([H])=NC(=C1C1=C([H])C2=C(C([H])=C1[H])N(C(=O)N2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(Br)=C1OC([H])([H])[H])C1=C([H])C2=C(OC1=O)C([H])=C([H])C(=C2[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])N([H])[C@@]([H])(C2=C3N=C([H])N([H])C(OC([H])([H])[H])=C3N=C2[H])[C@]([H])(O[H])[C@@]1([H])O[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=NC3=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C([H])=C3C([H])=C2C([H])=C1[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C2=NC(=NC([H])=C2[N+]([O-])=O)N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC1=NN([H])C(=N1)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(Br)C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
[H]OC([H])([H])C([H])([H])N(C(=O)C1=C([H])C2=C(N([H])C(=C2C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NOC(=N1)C1=C([H])C(=C([H])C(=C1[H])[N+]([O-])=O)[N+]([O-])=O
[H]OC(=O)[C@]([H])(OC1=C(C#N)C([H])=C([H])C(OC([H])([H])C2=C([H])C([H])=NN=C2[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])[C@]1(N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=NC2=C1C([H])=NN2C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C1=NC(=C([H])S1)C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC3=C([H])C(F)=C([H])C([H])=C3N3C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]OC(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(S[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])C1([H])C([H])([H])C(=O)N([H])C(=O)C1([H])[H])[C@@]1([H])C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N(\C([H])=C1/C(=O)N([H])C(=O)C2=C([H])C([H])=C(C([H])=C12)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(OC(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H]
[H]C1=C([H])C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(OC([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])C3([H])[H])C3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C2C3=C(N1[H])C([H])=C([H])C([H])=C3C(=O)N([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])[H])[C@@]([H])(C([H])([H])OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C(N=C1[H])C([H])([H])C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])F)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[C@@]1([H])[C@]2([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]12[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C#CC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(F)=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=NC([H])=C([H])C([H])=C2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])[C@@]([H])(N([H])[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2C3=C(O1)C(=O)C1=C([C@]([H])(OC(=O)C([H])([H])[H])C([H])([H])[C@@]4(C(=O)C([H])([H])C([H])([H])[C@@]14[H])C([H])([H])[H])[C@@]3(C([H])([H])[H])[C@]([H])(OC2=O)C([H])([H])OC([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])F)C([H])([H])C([H])([H])[C@@]22C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H]
[H]N(C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C(C#N)C([H])=NN2C([H])=C(N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C(=C12)C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C(Cl)C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(OC([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NC([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1S(=O)(=O)C2=C(C([H])=C([H])C([H])=C2[H])S1(=O)=O
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C(C#N)C2=C([H])C([H])=C(F)C([H])=C2C(SC([H])([H])C2=C(N=C([H])C([H])=C2[H])C#N)=N1
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)N([H])[C@]1([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(SC3=C2C2=C(N=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])=C3[H])C(=O)N([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])N(N([H])S(=O)(=O)C2=C([H])C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C1=O
CCOC(=O)CNC(=O)C(=O)C(COCC1=CC=CC=C1)NC(=O)[C@H](CC1CCCCC1)NC(=O)C1=CC(Cl)=CC=C1N(O)=O
[H]N1C(=NS(=O)(=O)C2=C1C([H])=C([H])C([H])=C2[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=NC(=C([H])C(=C2N=C1C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC2=C([H])C3=C(C([H])=C2[H])C(=C([H])C(O3)(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])=C1[H]
[H]N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(OC1=C([H])C(=C([H])C(C#N)=C1[H])C1=C([H])C([H])=C([H])C([H])=N1)C2([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@@](O[H])(C1=C([H])C(F)=C([H])C(F)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=NC2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])=NC([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC2=C(C3=C(C([H])=C2[H])C(=NO3)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])[H])C([H])([H])N([H])C2=C([H])C(F)=C(OC([H])([H])[H])C([H])=C2[H])=N1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[N@+]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C(OC([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]2([H])[C@@]3([H])C([H])([H])C([H])([H])[C@@]4([H])N(C(=O)C([H])([H])C([H])([H])[C@@]4(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]1([H])[C@@]([H])(N([H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])S(=O)(=O)C([H])([H])[C@@]1([H])C([H])([H])C1=C([H])C(F)=C(N([H])[H])C(OC([H])([H])C([H])(F)F)=C1[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(SC([H])=C1[H])C([H])([H])OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(SN=C2N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C(=O)SC4(C3=O)C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C2([H])[H])=C1[H]
[H]N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2F)C([H])([H])C2=C([H])N([H])C(=O)C3=C([H])C(Cl)=C(Cl)N23)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])C(=O)C2=C(C([H])=C(N([H])C(=O)C(\[H])=C(/[H])C3([H])C([H])([H])C([H])([H])N([H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(=N1)N([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=NN=C(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N([H])C1=C([H])C([H])=C([H])C(=C1[H])[C@@]1(N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])[C@@]2([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@@]12[H]
CC1=NC=C(N1CCOC(=O)\C=C\C1=C2C=CC=CC2=CC=C1)N(O)=O
[H]O[C@]1([H])[C@]([H])(O[H])[C@]2(C(=O)N([H])C([H])([H])[H])C([H])([H])[C@]2([H])[C@@]1([H])N1C([H])=NC2=C1N=C(N=C2N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N(N=N1)C1=C([H])C([H])=C(N=C=S)C([H])=C1[H]
[H]C1=NN=C([H])N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C(N([H])C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C12)C(=O)C1=NC([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@]([H])(N([H])C(=O)[C@@]1(N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C4=C([H])C([H])=C([H])N=C14)C([H])([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H]
COC1=CC(=CC=C1Cl)N1CCN(CC1)C(=O)CN1N=C(C(C)C)C(Cl)=C1C
[H]OC1=C(O[H])C([H])=C(N([H])C(=O)N([H])C(=O)C2=C(Cl)C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)[C@@]([H])(C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C2N(C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=N1)C(=O)N(N=C2C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3C([H])([H])SC2=C([H])C([H])=C(I)C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C2=C([H])N=C(C([H])=C2C([H])=C1[H])C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C(=C1[H])C(F)(F)F)C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])[C@@]1([H])[C@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C(=O)C3=C([H])C([H])=C(Cl)C([H])=C3[H])C3=C(C([H])=C(F)C([H])=C3N2C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1N=C(C(=C1[H])C1=C([H])C2=C([H])C([H])=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C2=C(C([H])=C([H])N2C2=NC3=C(C#N)C([H])=NN3C(N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1I)C(=O)O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])OC(=O)C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(OC1=C([H])C(=C(F)C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C4C([H])=NC([H])=C([H])C4=N3)=C2[H])N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])[C@]1(C(=O)N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C12)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
C[N]1=CC2=C(C=C1)C1=CC=CC=C1N2CCCCCCCCCCCCN1C2=CC=CC=C2C2=C1C=[N](C)C=C2
[H]C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]OC(=O)C1=C([H])N([H])C(=C(C(=O)OC([H])([H])C(\[H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]1([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])(OC([H])([H])[H])OC([H])([H])[H]
[H]OC(=O)C([H])([H])N1C2=C(C([H])=C(F)C([H])=C2[H])C2=C1C(=S)N(C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1F)C([H])([H])C2([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])[H]
[H]OC([H])([H])C1=C([H])C(OC([H])([H])C2=C(F)C([H])=C(F)C([H])=C2[H])=C(Cl)C(=O)N1C1=C(F)C([H])=C([H])C([H])=C1F
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N([H])C1=C([H])C(Br)=C([H])C([H])=C1[H]
NC(=O)N1CCC2=C(C1)C(=NN2CCCN1CCSCC1)C1=CC(C#CC2=CC=C(C=C2)C(=O)NC[C@@H]2CCCN2)=C(Cl)C=C1
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N(C1=C([H])C([H])=C(Br)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])[S@](=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])[C@]([H])(O[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C1=NN(C2=C([H])C([H])=C([H])C(\C([H])=C(/[H])C(=O)N([H])S(=O)(=O)C3=C([H])C(Cl)=C(Cl)S3)=C12)C([H])([H])[H]
[H]O\N=C(/[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C2(N(C3=C([H])C(F)=C([H])C([H])=C3[H])C([H])([H])N([H])C2=O)C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2=C([H])C([H])=C(C(F)=C2[H])C([H])([H])N2C(=NC3=C2C([H])=C([H])N=C3[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2N1C(=O)N(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]O[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=NN([H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2F)[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
[H]OC(=O)C([H])([H])N(C1=C([H])C([H])=C([H])C([H])=C1O[H])C([H])([H])C([H])([H])N(C1=C(O[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC([H])([H])C1=C(N=C(C(=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N([H])[C@](C1=O)(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N1C(=O)C2=C(C([H])=C([H])C(F)=C2[H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC([H])=NC(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C1=C([H])C(F)=C(F)C([H])=C1F
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N(C([H])([H])C([H])=C([H])[H])C([H])([H])C2=C([H])C3=C(N=C(N=C3O[H])C([H])([H])[H])C([H])=C2[H])C(F)=C1[H])C(=O)O[H]
[H]N([C@@]1([H])C([H])([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2N=C(C([H])=C2C(F)(F)F)C(F)(F)F)C1([H])[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
O=S1(=O)OC2=CC=C(OCC3=CC=CC=C3)C=C2C=C1
[H]N(C(=O)C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC([H])=C([H])C(=N2)N2C([H])=C([H])C3=C2C([H])=C([H])C([H])=C3N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[C@]1([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1F)N1C([H])=C([H])C([H])=C([H])C1=O)S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C(C#N)C(Cl)=C([H])C([H])=C1N([H])C(=O)N([H])C1=C(Br)C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C(C([H])=NC([H])=C1C#N)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NC(=C([H])N1C([H])([H])C(=O)N(C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])[C@@]([H])(C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C(F)(F)F
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1N([H])S(=O)(=O)C([H])([H])[H]
[H]ON(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])=C1[H]
COC1=CC(=CC=C1)C1=CSC(=N1)C1=CN=C(OC2=CC=C(CN3CCC4=C(C3)C=C(OC)C(OC)=C4)C=C2)C=C1
[H]N([H])C1=NON=C1C1=NC2=C([H])N=C([H])C(C(=O)N([H])C([H])([H])C([H])([H])N([H])C([H])([H])[H])=C2N1C([H])([H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2N=C([H])C3=C2N=C(N([H])[H])N2N=C(N=C32)C2=C([H])C([H])=C([H])O2)C([H])([H])C1([H])[H]
[H]N(C1=C2C([H])=C(C([H])=NC2=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])[C@@]1([H])[C@]([H])(OC([H])([H])C([H])([H])[H])OC(=C([H])[C@]1([H])C([H])([H])[H])C(=O)N([H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H]
[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C(C([H])=C([H])C([H])=C12)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])S(=O)(=O)C1=C2C([H])=C([H])C([H])=C(N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC3=C(O2)C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C2SC([H])=C([H])C2=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])([N+]([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]([H])([H])[H])[C@@]([H])(O[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C(=O)C([H])([H])C1([H])[H]
[H]N([H])C(=O)C(\[H])=C(/[H])C1=C(N2C(=O)\C(=C(/[H])C3=NC([H])=C([H])C([H])=C3[H])[C@@]2([H])S(=O)(=O)C1([H])[H])C([O-])=O
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1\C(S\C(=C(\[H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C1=O)=N\C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C([H])=C1F)S(=O)(=O)C1=C2N=C(C([H])=C(N2N=C1SC([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N=C(S1)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C([H])C(=N1)C([H])([H])SC1=C([H])C([H])=C([H])C(N([H])S(=O)(=O)C(F)(F)F)=C1[H]
[H]C1=C([H])C(=C([H])S1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(C2=NC3=C(S2)N=C([H])C([H])=C3[H])=C1C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(OC2=C(F)C([H])=C(F)C(OC3=C([H])C(=C([H])C([H])=C3[H])C(=N[H])N([H])[H])=N2)=C([H])C([H])=C1[H]
[H]C#CC1=C(N=C([H])C([H])=C1OC1=C([H])C([H])=C(N([H])C(=O)N([H])C(=O)C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1F)N([H])[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C([H])C(=C1N(C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C(=O)C([H])([H])C([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=C(F)C([H])=C([H])C(=C1[H])C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C2([H])[H]
[H]C1=C(C2=C([H])C([H])=C([H])N=C2N1[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N/C(=O)C([H])([H])C([H])([H])[H])\N([H])[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C1([H])C([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])S1)[C@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C(N=C1C1=C([H])SC(=N1)C([H])([H])[H])C(F)(F)F
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C(N([H])C(=O)C(C#N)=C1C([H])([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C(=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=NC(N([H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])N=C2C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C(SC([H])([H])[H])=N1
[H]C1=C(SC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)C(=O)C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[N@@+](C([H])([H])[H])(C([H])([H])[C@@]2([H])OC([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=C([H])C3=C(C([H])=C2[H])C([H])=C(O[H])C([H])=C3[H])C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])N(N=C2[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)N(C2=C([H])C(=NC([H])=C2[H])C([H])([H])[H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1Cl)C(F)(F)F
[H]N(C(=O)C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)C4=C([H])C([H])=C([H])C([H])=C4[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@]2([H])[C@@]3([H])C([H])([H])C([H])=C4C([H])([H])[C@@]([H])(O[H])C([H])([H])C([H])([H])[C@]4(C#C[H])[C@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]N1C(=C([H])C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C3([H])[H])=C([H])C([H])=C12)C(=O)OC([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=NN([H])C2=C([H])C(Br)=C([H])C([H])=C12
[H]N(C(=O)C1=C(C([H])=O)N(C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]C1=C([H])C([H])=C(O1)C([H])([H])N1N=NC([H])=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=C(S1)C1=C([H])N=C([H])C(Br)=C1[H])C1=C([H])C(=C([H])C([H])=N1)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])[H])C([H])([H])C([H])([H])OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C(N([H])C2=C([H])C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=NC(=N2)N2C([H])=NC3=C2C([H])=C([H])C([H])=C3[H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C([H])([H])N2N=C([H])N=C2[H])C([H])([H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=NC([H])=C1[H])N1C([H])([H])C(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N(N(C#N)C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(C(=O)C(OC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1Cl)C(=O)N([H])\N=C(/[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N=C1[H])N([H])C(=O)C1=C([H])C(=NN1C1=C([H])C([H])=C2C([H])=C(Cl)C([H])=C([H])C2=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])Br)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C(C([H])=N1)C([H])([H])C1=C([H])C(=C2N=C(OC([H])([H])[H])C([H])=C(C2=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C(=O)[C@@]([H])(N(C(=O)C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])[H])C([H])([H])C(=O)O[H]
[H]OC1=C([H])C([H])=C(C(Cl)=C1[H])[C@]1([H])N([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C3C(=NC([H])=C2[H])N([H])C([H])=C13
[H]N(C1=NC(C2=C([H])N=C3C([H])=C(C([H])=C([H])N23)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(Cl)C([H])=N1)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C(C([H])([H])N2N=C([H])N=C2[H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C2=C(N([H])C(=O)\C2=C(\[H])C2=C([H])N(C3=C2C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])C1=NN([H])C(=O)C2=C1N([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N1C(=O)N([H])C2=C([H])C(=C([H])C([H])=C12)C1=C2N=C(C([H])=NC2=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N(N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=NC1=C2C(=NN(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(S2)C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C1C([H])([H])[H]
[H]N(C1=NC(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=NC(=C(O1)C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N(C1=NC(=O)\C(S1)=C(/[H])\C(\[H])=C(/[H])C1=C([H])C([H])=C([H])O1)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N([H])C(=O)N([H])\N=C(\C1=C([H])C([H])=C(O1)C1=C(SC([H])=C1[H])C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(Cl)=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@]1([H])N(C(=O)C2=C([H])C(I)=C([H])C([H])=C2N(C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=O)N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C2=O)C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])N(C1=C([H])C(OC([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC(F)(F)C([H])(F)F)=C1[H])C(F)(F)F
[H]N([H])C(=NC(=O)C1=C(N([H])C(=O)C([H])([H])[H])C([H])=C(O1)C1=C(Cl)C([H])=C([H])C(Cl)=C1[H])N([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]1([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])SC([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])[C@]1([H])N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C1N([H])C1=C([H])C([H])=C(C([H])=C21)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])O[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])N(C(=O)C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C2=C(N=C([H])C([H])=C2[H])C2=C([H])N=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
CC1=CN=C(CNCC2(O)CC3CCC(C2)N3C(=O)C2=CSC=C2)C=C1
[H]N([H])C1=C([H])C2=NC([H])=C(N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C(=O)[C@]([H])(N([H])C(=O)C1=C(Cl)C(=C(OC([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])S(=O)(=O)C2=C([H])C3=C([H])C([H])=C(Cl)C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
CCCCCCCCN1C=C(CCC(N)=O)C2=CC(=CC=C12)C1=CC(C)=CC=C1
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])SC1=NC(=C(N1[H])C1=C([H])C([H])=NC(N([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N([H])C1=NC([H])=NC2=C1C([H])=C([H])C(N1C([H])=C(C3=C1C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C3=O)C([H])([H])[H])=C2F
[H]C1=NC(=C([H])C([H])=C1[H])C1=NOC(=N1)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]N(C(=O)N1C(=O)N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)[C@]1([H])C([H])([H])C2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)[C@@]12C([H])([H])C([H])([H])[C@@](C3=NC4=C(N3[H])N(C(=O)N(C4=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1N1N=NN=C1[H]
[H]N([H])[C@@]1([H])C(=O)N([H])OC1([H])[H]
[H]C1=C([H])C(OC([H])([H])C(=O)O[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1Cl)C([H])([H])[H]
[H]N([H])C1=NC2=C(OC3=NC([H])=NC(=C3[H])C3=C(N=C(C([H])=C3[H])C(F)(F)F)N([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C([H])C([H])=C2N([H])C1=O
[H]C1=C([H])C(C(=O)C([H])([H])[H])=C2C(=C1F)C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C3(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1=O)C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C([H])([H])C1=C([H])OC2=C1C(N([H])[H])=C([H])C(=N2)N([H])[H])C([H])([H])C([H])([H])[H])C(=O)O[H]
CC1(C)CCC2=C(N=C3SC4=C(N=CN=C4NCCN4CCOCC4)C3=C2C1)N1CCCC1
[H]OC1=C(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC(=O)[C@]1([H])C([H])([H])N(C2=C(F)C(OC3=C([H])C(=C([H])C([H])=C3[H])C3=NC([H])([H])C([H])([H])N3C([H])([H])[H])=NC(OC3=C([H])C(=C([H])C([H])=C3O[H])C(=N[H])N([H])[H])=C2F)C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C2N(C(=NC2=C1C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N2C([H])=C([H])N=C2C(=N1)N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N=C(N=C1[H])N([H])C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]C1=C([H])C2=NC(=C([H])C([H])=C2C(=C1[H])C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C([H])C([H])=C4OC(=NC4=C3C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]12C3=C([H])C([H])=C([H])C([H])=C3[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C2([H])[H]
CC(=O)N[C@@H](CC1=CC(F)=CC(F)=C1)[C@H](O)CNC1(CCCCC1)C1=CC=CS1
[H]N([H])C1=C(N2C([H])=C([H])N=C2C([H])=C1[H])N1C(=O)[C@@]2([H])[C@@]([H])(C1=O)[C@]1(O[C@]2(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])([H])C([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2OC(=O)C3=C(C2=C1[H])C([H])([H])C([H])([H])C([H])([H])N3[H]
[H]OC(=O)[C@@]1([H])N(C(=O)C(\[H])=C(/[H])OC([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=NC(=N1)N([H])[H])N1C([H])([H])C([H])([H])[C@@]([H])(O[H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]1([H])C(=O)N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C2N(C([H])([H])[H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3(C2=C1[H])C([H])([H])[H])C1=C(Br)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C2=C(C([H])=C([H])C(=C2[H])S(=O)(=O)N([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(OC2=C(C([H])=C([H])C(Cl)=C2[H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@@]1([H])C(=O)N(C([H])([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]([H])(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C1=C([H])N2C([H])=C(C([H])=C([H])C2=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C([H])([H])N(C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C(=O)C1=C([H])C2=C(O1)C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]N([H])C1=C(C([H])=C([H])[N+]([O-])=C1C1=C([H])C([H])=C([H])C([H])=C1Cl)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC2=C1C([H])=C([H])C(Cl)=C2[H])C([H])([H])OC1=NN(C(=C1[H])C1=NC2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC2=C1N([H])C([H])=NC([H])([H])[C@@]2([H])O[H]
[H]C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(P([O-])([O-])=O)S([O-])(=O)=O)C([H])=C1[H]
[H]N1C2=C([H])C(=C([H])C([H])=C2N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)OC1=C([H])C([H])=C(\C([H])=C(/[H])[N+]([O-])=O)C([H])=C1[H]
[H]N([H])C1=C([H])C(=C(C(=N1)C([H])([H])[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC([H])=C1C([H])([H])[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)N3C([H])([H])C([H])([H])C([H])([H])[C@]3([H])C2=O)C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C(C([H])=C(S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=NC([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C3=C([H])C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])SSC1([H])[H])C([H])([H])O[H])C([H])([H])C([H])([H])C2([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1
[H]OC(=O)C(\[H])=C(\C(\[H])=C(/[H])\C(\[H])=C(/C1=C([H])C(=C([H])C(=C1OC([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])/C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C1=C(OC(=C([H])C1=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])[C@]2(C(C([H])=C([H])[C@@]3([H])[C@@]4([H])C([H])([H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]23[H])=C([H])C1=O)C([H])([H])[H]
[H]N([H])C1=C2C(=NC3=NC(OC([H])([H])[H])=C(C#N)C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=C(N2C(=N1)C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[Na+].[Na+].COC1=C(C=CC(NC2=CC(=C(N)C3=C2C(=O)C2=CC=CC=C2C3=O)S([O-])(=O)=O)=C1)C1=C(OC)C=C(NC2=CC(=C(N)C3=C2C(=O)C2=CC=CC=C2C3=O)S([O-])(=O)=O)C=C1
[H]OC(=O)[C@@]([H])(N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C1=C(F)C(O[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])=C([H])C(OC([H])([H])C([H])([H])[H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(F)=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)C1=C([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2N1C([H])([H])C(=O)O[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C1C([H])=C([H])C(Cl)=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC1=C2O[C@@]3([H])[C@@]4(N([H])C(=O)N([H])C4=O)C([H])([H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(C2=C([H])C([H])=C(F)C([H])=C2S1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2N=C(C3=C2C([H])([H])C([H])([H])N(C3([H])[H])S(=O)(=O)C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C2SC(=C([H])C2=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C1=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])C2=NC([H])=N1
[H]N(C(=O)[C@]([H])(N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NO1)[C@@]([H])(C(=O)N([H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC(=NC2=C([H])C([H])=C(Cl)C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]N(C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H]
[H]N(C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
CN1C=C(CC(=O)NC23CC4CC(CC(C4)C2)C3)C2=CC(=CC=C12)C1=CC=CC=C1
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])[C@]([H])(N([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])S1
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C2=C1C([H])=NN2S(=O)(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C(SC([H])([H])C2=C([H])C([H])=C(O2)C(=O)N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])S1
[H]N(C(=O)C1=C(C([H])=C([H])S1)S(=O)(=O)N([H])C1=C(Cl)C(=NO1)C([H])([H])[H])C1=C(C([H])=C(C([H])=C1S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(OC([H])([H])[H])C(=O)C1=C([H])C2=C(N=C(N=C2N([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])N2C([H])=NC3=C2C([H])=NC([H])=C3[H])N1C([H])([H])[H]
[H]OC(=O)C1=C(O[H])C([H])=C2OC(=C(C3=C([H])N(N=N3)C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])OC([H])(C3=C([H])C([H])=C(F)C([H])=C3[H])C3=C([H])C([H])=C(F)C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]C([H])([H])C#CC([H])([H])C#CC([H])([H])O\N=C1/C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N(N1C(=NC(=C1C([H])([H])[H])C([H])([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C(Cl)=C([H])C(F)=C1C1=NOC(=N1)C([H])([H])[H])C(=O)C([H])([H])[H]
[H]C([H])([H])N1C2=C(N3C(=N2)N(C([H])([H])C([H])([H])C3([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=O)N(C1=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C(SC2([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C3N([H])C(=NC3=C3N([H])C(=NC3=C12)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C(C1=C([H])C2=C(N([H])C(=C2C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N([H])C1=C(Br)C(=NC2=C(C([H])=NN12)C1=C([H])N(N=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1(C([H])([H])S[C@@]([H])(C2=C([H])C(\C([H])=C(/[H])C3=NC4=C(SC(Cl)=C4Cl)C([H])=C3[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])SC([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N=C2N=C(N=C(N([H])[H])C2=N1)N([H])[H]
[H]N1C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NC(=C1C1=C([H])C([H])=NC(F)=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1[C@@]2([H])C3=C(N(C4=C([H])C([H])=C(C([H])=C34)S(=O)(=O)N3C4=C(C([H])=C3C([H])([H])[H])C([H])=C([H])C([H])=C4[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=N3)C([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])C([H])=C1[H])C(F)(F)F
[H]OC1=NC2=C([H])C([H])=C([H])C3=C2N=C1C1=C2SN(C(=O)C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])O3
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C2=C(C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C(=O)N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]\C(=C1\C2=C([H])C([H])=C(F)C([H])=C2C([H])([H])C1([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC(=O)C(=O)N(C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]ON([H])C(=O)[C@@](O[H])(C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(F)C([H])=C2[H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2N(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C(=O)N(C2=C(C(=C([H])C(OC([H])([H])[H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(N([H])[H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2S(=O)(=O)C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]2([H])N([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C(SSC1([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]SC([H])([H])[C@]([H])(N([H])[H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])N(N=C1[H])C1=NC([H])=C(C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(Cl)C(=C1[H])S(=O)(=O)N([H])[H]
[H]N(C1=C2C([H])=C(C([H])=NC2=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(N3C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C3([H])[H])=C(N([H])C(=O)C3=C([H])C([H])=C(O3)C#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C(N=C1C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])=C([H])C(=C2[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
CCC1=CC2=C(CC(C)(C2)NC[C@H](O)C2=C3C=CC(=O)NC3=C(O)C=C2)C=C1CC
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)N(C([H])([H])C1=C([H])C([H])=C([H])C(C#N)=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])[C@]2(O[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(N=C1[H])C([H])([H])C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C12
[H]N(C1=NC([H])=C2C(=N1)N(C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(Cl)C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=NC([H])=C(S1)[C@@]([H])(C#N)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON(C(=O)N([H])[H])[C@]1([H])C2=C([H])C3=C([H])C(Cl)=C([H])C([H])=C3N2C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]([H])(OC([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(O1)C(=O)N(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C1=C(N([H])[H])N(N=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C3C4=C([H])C([H])=C([H])C([H])=C4C(=O)C(N=C1[H])=C23)C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)[C@@]([H])(N1C([H])=NC([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(N=C(S2)N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])ON3C(=O)C([H])([H])C4(C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3=O)C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(S1)C1=NC(=NC([H])=C1[H])N([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C1=O
[H]N(C(=O)[C@@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])OC(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C1=C([H])C(=C([H])C([H])=C1[H])N1N=C(C2=C1C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(F)(F)F)S(=O)(=O)C([H])([H])[H]
[H]C1=NC([H])=C2N1[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C2([H])[H]
[H]N1C([H])([H])C2=C(N(N=C2C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C2=C(OC(=N2)C2=C([H])C(F)=C(F)C([H])=C2Cl)C([H])=C1[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(F)=C2[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C3=C([H])C([H])=C([H])C4=C3C(=C([H])C([H])=C4[H])S2(=O)=O)C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])[C@]2(C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N(C(=O)C1=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)C1=C([H])C([H])=C2N=C(C([H])=C([H])C2=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C1=NN=C(N([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2OC([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)C([H])([H])N(C(=O)C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]([H])([S@@+]([O-])C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
NC(=O)[C@@]12CC3CC(C1)[C@H](OC(=O)N1CC[C@H](C1)NC1=C(C=CC=N1)C#N)C(C3)C2
[H]N(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C2=C(C3=C([H])C([H])=C([H])C([H])=C3[H])[N+](=C3C([H])=C(N([H])[H])C([H])=C([H])C3=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=NN1C([H])([H])C([H])([H])N([H])C1=C2C([H])=C([H])C([H])=C([H])C2=NC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(S1)C(=N[H])N([H])N([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C2=C([H])SC([H])=C2[H])C1([H])[H]
[H]OC1=C([H])C(=C(O[H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C(/C1=C([H])C([H])=C([H])O1)C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C(Cl)=C([H])C(Cl)=C1OC([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C([H])=C(C(=O)N2C([H])([H])C([H])([H])C3(C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2OC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C3([H])[H])C1=O
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@](C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C1([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@](O[H])(C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C(F)(F)F
[H]N(C1=C(C#N)C(F)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C(O1)C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(S1)C([H])([H])C([H])([H])SC1=C2C([H])=C(F)C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C(OC([H])([H])[H])C([H])=C(C([H])=C3[H])C3=NC4=C(S3)C([H])([H])C([H])([H])C([H])([H])O4)C([H])=C2C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1C([H])([H])N([H])[H])C([H])([H])C([H])([H])C1=[N+]([O-])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])C(=O)N(C2=C([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2(C(=O)OC([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N([H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C2([H])[H])[C@]1([H])N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])N([H])C([H])=C(C(=O)OC([H])([H])C(\[H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]C1=C([H])C(=NN2C1=NN=C2C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])C(O[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C(Br)=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N([C@]([H])(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(Br)=C2C([H])=C([H])C([H])=C([H])C2=C1OC([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1N=C(C([H])=C2[H])C1=NN=C2C([H])=C([H])C([H])=C([H])N12)C([H])([H])C([H])([H])[H]
CC(=O)NCC(=O)N1CCC2(CC1)CCN(CC1=CC=CC=C1C)C1=C(O2)C=CC=C1
[H]OC(=O)[C@]([H])(C([H])([H])C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])[H]
[H]N(C1=NN(C2=C1C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])[H])C([H])([H])C(=O)N([H])C1([H])C([H])([H])N(C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C(N=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C(C(=O)N(C1=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])OC([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(N([H])S(=O)(=O)C2=C(N([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N1C(=O)C2=C3C(N([H])C4=C3C([H])=C(C([H])=C4[H])C3=C([H])SC(=N3)C([H])([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C3C(=C2C1=O)C([H])([H])C([H])([H])C3([H])[H]
[H]N(C1=C2C(SC3=C2C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C3([H])[H])=NC(=N1)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])N1C(=NC(=C1C(=O)C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C(=O)N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N1C(=O)N(C(=O)C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)C1=NC2=C(O1)C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])C(=O)N1C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]1([H])C3([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N(C1=C(OC2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(OC([H])([H])C([H])([H])OC2=NC([H])=C(OC([H])([H])[H])C([H])=N2)=NC([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(N1C(SC([H])([H])C#N)=NN=C1C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C([H])([H])Cl)C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])SC1=NN=C(N1C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C1=NN=C([H])S1
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=N1)C(F)(F)F)C1=C([H])N2C([H])=C(N=C2C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(=C2[H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])N(C2=C1C([H])=C1C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1(N([H])C(=O)C([H])(F)F)C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C(=O)OC([H])([H])[H]
[H]N([H])C(=O)C1=C2C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]21[H]
[H]N(C(=O)C([H])([H])N(C(=O)C([H])([H])C([H])([H])C1=NC2=C(C3=C(S2)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(=O)N1[H])C([H])([H])C([H])([H])[H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]N1C2=C([H])C([H])=C(OS(=O)(=O)C([H])([H])[H])C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(C(=O)N([H])\N=C1/C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)N(C([H])([H])[H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=C([H])C(=C1[H])C([H])(F)F)C1=C([H])C(OC([H])([H])C2([H])C([H])([H])C2([H])[H])=C(OC([H])(F)F)C([H])=C1[H]
[H]O[C@]1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])S2)C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C([H])=C([H])C(=C2[H])N1C(=C(C2=C1C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2=O)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N1C(=O)C2=C([H])C(I)=C([H])C([H])=C2N([H])C(=O)[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C2=C(N=C(S2)N2C(=O)O[C@@]3(C2([H])[H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]3([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NOC3=C([H])C(F)=C([H])C([H])=C23)C([H])([H])C1([H])[H])C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=NC2=C([H])C([H])=C(Cl)C([H])=C12)N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C1=NC([H])=C(Cl)C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C(=O)N([H])C2=C([H])N(N=N2)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C2N=C([H])N(C3=C([H])SC([H])=C3[H])C2=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2N1[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C1=C(C(=O)OC1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OP(=O)(O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(Br)=C1[H]
[H]N1C(C(=O)OC([H])([H])C([H])([H])OC([H])([H])[H])=C(C2=C1C([H])([H])[C@]([H])(C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C2=O)C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1N=C2OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])C([H])([H])[C@]1(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[C@@]([H])(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C2=C([H])C(=C([H])C([H])=C2C1([H])[H])[N+]([O-])=O
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)O[H])C(=O)N([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2F)C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N(C(=O)C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C([H])=C2N1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(C2=C(Br)C([H])=NN2C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C2C(=O)C([H])=C(OC2=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N(C3=C(SC2=C1[H])C([H])=C([H])C(=C3[H])[S@+]([O-])C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C(C(=O)OC([H])([H])[H])(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])[C@@]([H])(C2=C([H])C(F)=C(F)C(F)=C2[H])C(C(=O)OC([H])([H])[H])=C1C([H])([H])OC([H])([H])[H]
[H]N1C(=NC(C2=C([H])C([H])=C(F)C([H])=C2[H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(P([O-])([O-])=O)S([O-])(=O)=O
[H]N1C2=C3C([H])=C(OC4=C(C#N)C([H])=C([H])C(=C4[H])C([H])([H])N4C([H])=NC([H])=C4C([H])([H])N([H])[C@@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C([H])S1)C([H])=C([H])C3=C([H])C([H])=C2[H]
[H]N(C1=NC([H])=C([H])C(=C1[H])C1=C(C(=O)C2=C([H])C([H])=C([H])C([H])=C2O1)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(C2=NC(=C3N2C2=C([H])C(=C([H])C(OC([H])([H])[H])=C2N=C3C([H])([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])=C(C([H])=N1)C([H])([H])[H]
[H]C1=C(OC2=C([H])C([H])=C([H])C([H])=C12)[C@@]1([H])N2C([H])([H])C([H])([H])C([H])([H])[C@]22C(=O)N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]N(C1=NC2=C(C([H])=N1)N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C(=NC3=C2N=C([H])N=C3N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]1([H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
CN(CC1=CN=CC=C1)C(=O)C1=C(OC2=CC=CC(Cl)=C2Cl)N(C)N=C1C
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C1=NC2=C(N=C([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]\C(I)=C(\[H])C([H])([H])N1C(=O)N(C(=O)C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C#N)C([H])=C1[H])C(F)(F)F
[H]O[C@@]([H])(C1=C([H])SC2=C([H])C([H])=C(F)C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3OC([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2C(=O)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])N=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC1=C(C([H])=C(C(=O)C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(N([H])[H])=C(C([H])=C1C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)N1C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(SC(=C1[H])C1=NN=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C(F)(F)F
[H]N([C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(C#N)(C([H])([H])[H])C([H])([H])[H])C(C#N)(C([H])([H])[H])C([H])([H])[H]
O=C(CCC1=CC=CC=C1)NC1CCN(CCCN2C(=O)COC3=C2C=CC=C3)CC1
[H]C1=NC([H])=C(C([H])=N1)C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]12[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N2C(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C(N=C2N=C(C([H])=C(N12)C([H])([H])[H])C([H])([H])[H])C([H])([H])OC1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]C1=C(C([H])=C2C([H])=C(OC(F)(F)F)C([H])=C([H])C2=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C([H])C(=N1)C1=C2C([H])=C([H])N=C(N([H])[H])N2C2=C1C(OC([H])([H])[H])=C([H])C([H])=N2
[H]N([H])C1=NC([H])=C2C([H])=C(C(=NC2=C1[H])N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NOC(=N1)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(O[C@]([H])(C2=C(N=C(OC([H])([H])C3=C(ON=C3C3=C(Cl)C([H])=C([H])C([H])=C3Cl)C3([H])C([H])([H])C3([H])[H])C([H])=C2[H])C(F)(F)F)C([H])([H])[H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])\C(\[H])=C(\C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)N1C(=O)N([H])C(=C(C(=O)OC([H])([H])[H])[C@@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(OC(=O)C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(OC2=C(N([H])S(=O)(=O)C3=C(Cl)C([H])=C(Cl)C([H])=C3[H])C([H])=C(C([H])=C2[H])C(=O)N([H])C2([H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC3=C(SC([H])=C3[H])C(=O)N2C([H])([H])C2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(OC(F)(F)F)=C1[H])[C@]1([H])OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]O[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])=C([H])C([H])=C([H])[C@]12[H]
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])[H]
[H]N1C([H])([H])C(=O)N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])[C@@]([H])(C([H])([H])OC([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C1([H])[H]
[H]SC([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C(Cl)=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C1=C(OC([H])([H])C(=O)O[H])C(Br)=C(S1)C1=C([H])C(N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N1C(=O)N(C2=NC(=NC([H])=C12)N1C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])[C@@]1([H])C2=C(OC([H])([H])C1([H])[H])C([H])=C([H])C(F)=C2[H]
[H]OC1=C([H])C([H])=C(N=N1)C(=O)N([H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N([H])C2=O)C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(Br)C([H])=C1OC([H])([H])[H]
[H]N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1(OC(=O)C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[C@]1([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=NN=C1C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(N=C(N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])S1)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])OC1([H])C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(OC([H])([H])[H])C(=C(OC([H])([H])[H])C([H])=C1Cl)C1=NC(OC([H])([H])[H])=C(OC([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=N1)C([H])([H])[H]
[H]N([H])C1=C([H])N2C(=NC(=C2C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C(C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(=N/OC([H])(C([H])([H])[H])C([H])([H])[H])\C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C1=C([H])N([H])C([H])=N1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@](C(=O)OC([H])([H])[H])(C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H][C@@]12CC(=O)CC[C@@]1([H])C(C)(C)OC1=C2C(O)=CC(=C1)C1(CCCCC#N)CCCC1
[H]N(C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])[N+]([O-])=O
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C(\[H])=C(/[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C#CC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C1=NC2=C(N=C([H])N2C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])S2)C(=N1)C1=C([H])C([H])=C([H])O1
[H]OC(=O)C1=C(OC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C2=NN([H])N=N2)C(=NC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]C1=C2N(N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=NC1=C2C(=NN(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C2=NN=C(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C(Br)=C1[H]
COC1=CC(OCC2=NC3=C(N2C)C(=O)N(C)C(=O)N3C)=CC=C1
CCOC(=O)C1=CC=CC(=C1)B(O)O
[H]N(C(=O)C1=NC(SC2=NN=C([H])N2[H])=C([H])C([H])=C1SC1=C([H])C([H])=C([H])C([H])=C1F)C1=NC([H])=C([H])S1
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H]
[H]N(C([H])([H])C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1N=NN=C1C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N([H])[H]
[H]O[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(N([H])[H])C([H])([H])SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1(C(=O)N([H])C([H])([H])C(F)(F)F)C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=C2N(C(=O)N(C2=N1)C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])S1)S(=O)(=O)N([H])C1=C(Cl)C(=NO1)C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
CS(=O)(=O)NC1=C2N=C(C=C(O)C2=CC=C1)C(=O)NC1=CC=CC=C1C(F)(F)F
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(F)C([H])=C(Br)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C(N=C1C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C(F)(F)F
[H]\C(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])=C1\C([H])([H])N2[C@]3([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C([H])([H])OC2=C([H])C([H])=C(I)C([H])=C2[H])[C@@]1([H])C3([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2([H])C([H])([H])C2([H])[H])C([H])=C1OC1=NC([H])=C(C([H])=C1Cl)C(F)(F)F)S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=C(C#N)[C@@]([H])(C2=C(Cl)C([H])=C(F)C([H])=C2[H])C(C(=O)OC([H])([H])[H])=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C(=NC3=C2C([H])=C([H])N=C3[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2N1C(=O)N(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])C([H])([H])[H]
COC1=CC=C(C=C1C(C)(C)CC(O)(CC1=CC2=CC=NC=C2N1)C(F)(F)F)C1=CC=NC=C1
[H]C1=C([H])N=C(C([H])=N1)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C(N=C3[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])C([H])([H])S[C@@]1([H])OC2=C(C([H])=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])C(=O)[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])[H])N([H])[H]
[H]N1[C@]([H])(SC([H])([H])[C@@]1([H])C(=O)C1=C(N(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C1C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC(=O)C([H])([H])N1C2=C([H])C([H])=C(F)C([H])=C2C(=C1C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC([H])([H])[H])C1=NN(C2=C1C([H])=C1C([H])=C(C([H])=C([H])C1=N2)C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(O[C@@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@]([H])(C1([H])[H])[C@@]([H])(OC([H])([H])OC([H])([H])[H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1(SC2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C#N)C2=C(C(SC([H])([H])C3=C(C#N)C([H])=C([H])C([H])=C3[H])=N1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C1=NC2=C([H])C(OC([H])([H])[H])=C([H])C(=C2C(=O)O1)C1([H])C([H])([H])C1([H])[H]
[H]N1N=C(C(C2=NC(=C3N2C2=NC(OC([H])([H])[H])=C([H])C([H])=C2N=C3C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@]([H])(OC1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])SC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(I)C([H])=C1[H])C([H])([H])C(=O)O[H]
[H]N=C(N([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])N([H])C1=C(Br)C(=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C#N)N1C([H])([H])C([H])([H])N(C(=O)[C@]23C([H])([H])[C@]4([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@](C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])(C4([H])[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C(SC4([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])N=C23)N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N=C(N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]\C(=C(\[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C2=NC(=NC([H])=C2[N+]([O-])=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2Br)C([H])([H])C1([H])[H]
[H]N([H])C1=NON=C1N1N=NC(C(=O)N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C(=O)N([H])[C@]([H])(C([H])([H])OC1=C([H])C2=C(N=C(N(C2=O)C([H])([H])C(=O)N([H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])C1=C(Cl)C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(OC([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])N(C([H])([H])C4=NC5=C(C([H])=C([H])C([H])=C5[H])N4C([H])([H])[H])C([H])([H])[C@]23[H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])N(C(=O)C1=C([H])C2=C(N=C(O2)N(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])=O
[H]C1=NC(Cl)=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C(Cl)C(Cl)=C([H])C([H])=C1[H]
[H]C1=NC(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])[C@@]4(C([H])([H])C3([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]4([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC(=O)[C@]([H])(OC1=C(C#N)C([H])=C([H])C(OC([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])[C@@]1([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C(F)=C2F)C([H])([H])C1([H])[H]
[H]N1C(=O)N(C2=C(N=C(SC3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1Cl)C(=O)OC([H])([H])[H]
[H]N([H])S(=O)(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N([H])C(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1\C([H])=C(/[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(C([H])=C([H])C3=C2[C@@]([H])(OC2=C3C([H])=C(F)C([H])=C2F)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])=C1[H]
[H]N([H])N1C(=O)C([H])=C2C([H])=C3OC([H])([H])OC3=C([H])C2=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=C(N2C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Cl)=C(N([H])C([H])([H])C2=NC3=C(N=C(N=C3N=C2[H])N([H])[H])N([H])[H])C(Cl)=C1[H])C(=O)O[H]
[H]OC([H])([H])[C@@]([H])(N([H])C1=NC(N([H])[H])=C2N=C([H])N(C2=N1)[C@]1([H])C([H])([H])[C@]([H])(N2N=C([H])C([H])=C2[H])[C@@]([H])(O[H])[C@@]1([H])O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H])C1=C([H])C(=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]O[C@@]1(C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N(C1=NC([H])=C([H])C2=C(N([H])C3=C(C([H])=C([H])C([H])=N3)C3=NC([H])=NC(N([H])C([H])([H])[H])=C3[H])C(=C([H])C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(C2=NN(C3=C2N=C(C([H])=C3N(C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]C([H])([H])C1=C(C(=O)ON1C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C([H])C(Cl)=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(N1C2=C([H])C([H])=C(Cl)C([H])=C2SC2=C1C([H])=C([H])C([H])=C2[H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
COC(C)(C(C)C)C1CN(CCN1)C1=CC=C(F)C(=N1)C1=NNC2=C1C=CC=N2
FC1=CC=C(C=C1F)N1CNC(=O)C11CCN(CCNC(=O)C2=CC=C3C=CC=CC3=C2)CC1
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@]2(OC(=O)C2=C([H])C([H])=C([H])O2)C(=O)C([H])([H])SC2=NC([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C(=O)C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]12[H]
[H]OC(=O)C1=C(C([H])=C(C([H])=C1[H])C1=C([H])C(=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C(F)C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]N([C@]1([H])C([H])([H])OC([H])([H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)N=C1[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(N([H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F)C(=N\C1=C([H])C([H])=C([H])C([H])=C1[H])\C(=O)C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])S1)C([H])([H])[N+]1([H])C([H])([H])C([H])([H])N(C2=NSC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])N=C=S)[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])O[H]
[H]N(C(=O)C1=C(N(C2=C([H])C(=C([H])C([H])=C12)C(=N\OC([H])([H])[H])\C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])N=C(C([H])=C1OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])C(=O)C([H])([H])C([H])([H])[C@@]4(OC([H])([H])C([H])=C([H])[H])[C@]5([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N1C(=C(C(=O)C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C(=C12)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NO[C@@](C(=O)N([H])C2=C([H])C([H])=C(N=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])(C([H])([H])C(=O)OC([H])([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C(C#N)=C2[H])[C@]1([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(Br)O1)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2N=C([H])C(=N2)C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2F)C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])N=C(\C([H])=C(/[H])C2=C([H])C([H])=NC([H])=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N1C1=C(\C([H])=C(/[H])C2=C([H])C([H])=NC([H])=C2[H])C(=C(\C([H])=C(/[H])C2=C([H])C([H])=NC([H])=C2[H])C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C2=C1N=C(C([H])=C2[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1(OC2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])N([C@@]([H])(C1=O)C([H])([H])C(=O)N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C(Cl)C(Cl)=C([H])C([H])=C1[H]
COC1=CC(\C=C2/CCC\C(=C/C3=CC(Cl)=CC=C3)C2=O)=CC(OC)=C1
[H]N(C(=O)C([H])([H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(O1)C([H])([H])[H])C1=NC([H])=C([H])S1
[H]O[C@@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1N(C(=O)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C2OC([H])([H])C([H])([H])OC2=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN([H])C2=C1C(=NC([H])=N2)N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NN([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(N([H])C(=O)C2=C([H])C(=NC([H])=C2[H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=S)N([H])[C@@]([H])(C1=C([H])C(OC([H])([H])[H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1C(=O)C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C(=O)N([H])C2=NC([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])[C@]2(C1([H])[H])C([H])([H])C1([H])N(C([H])(C3=C(Cl)C([H])=C([H])C([H])=C3[H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])[C@@]([H])(C([H])([H])C1([H])[H])C2([H])[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])[C@@]3([H])C([H])([H])[C@@]3(C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C([H])([H])C1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=NC(=NO2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H][C@@]12C[C@]1([H])[C@H]([C@H](O)[C@@H]2O)N1C=NC2=C1N=C(N=C2NCC(C1=CC=CC=C1)C1=CC=CC=C1)C#CC1=CC=CC=C1
[H]N([H])C(=O)N([H])C1=C(C(=O)N([H])[H])C2=C(S1)C1=C([H])N(N=C1C([H])([H])C2([H])[H])C1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])\N=C(/S[H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C(N([H])[H])=C(C([H])=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N(C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C3=C2C(=C([H])C(=C3[H])C(=O)C([H])([H])Cl)C1=O
[H]N(C(=O)C1=C([H])C2=C([H])C(N([H])C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2N1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
OB(O)C1=CC2=CC=CC=C2S1
COC1=CC=C(C=C1)N1C(CN2C=CN=C2)=CC2=CC=C(C)C=C12
[H]OC1=C(I)C([H])=C2C(=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@@]([H])(C2([H])[H])[C@@]1([H])C([H])([H])[H]
[H]OC(=O)C(=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])\C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])O\N=C(/C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N1C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C(C#N)C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])=C12
[H]N(C(=O)C1=C([H])C(Br)=C(N=C1OC([H])([H])[H])N([H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N1C(=O)N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])N(C4=C([H])C([H])=C(C([H])=C34)C3=C([H])N=NN3C([H])([H])[H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1(F)[C@]2([H])C([H])([H])[C@@]([H])(OC([H])(C3=C([H])C([H])=C(F)C([H])=C3[H])C3=C([H])C([H])=C(F)C([H])=C3[H])[C@@](N([H])[H])(C(=O)O[H])[C@]12[H]
[H]OC(=O)C1=C([H])C([H])=C(OC([H])([H])[C@]2([H])N([H])[C@]([H])(C(=O)N3C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C#N)C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(Cl)C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])C(=O)N2C3=C(C([H])=C(F)C([H])=C13)C([H])([H])C1=C2C([H])=C([H])C(F)=C1[H])C1=NC([H])=C(S1)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)O[C@@]1([H])C([H])([H])N([C@]([H])(C(=O)OC([H])([H])[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])OC(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])=C(C([H])([H])[H])[C@@]1([H])C2([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C(N([H])C([H])=N1)C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])C4=C(C5=C(N4[H])C4=C(C([H])=C5[H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C(=O)C([H])([H])SC1=NN=C(N1C([H])([H])C1=C([H])C([H])=C([H])O1)C1=C(OC([H])=C1[H])C([H])([H])[H])C1=NC([H])=C([H])S1
[H]N(C(=O)[C@@]1([H])OC(=O)N([H])[C@@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1([H])C([H])([H])N(C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=S)N([H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F)C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C(N([H])C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C23)=C1[H])C([H])([H])[H]
[H]OC1=C(O[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C2=C13
[H]N(C1=C([H])C([H])=C([H])C(=N1)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])N12)C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(OC2=NC([H])=NC3=C2C(=C([H])S3)C2=C([H])C([H])=C(F)C(F)=C2[H])C(F)=C1[H]
[H]N(C(=O)C1=C(F)C([H])=C(F)C([H])=C1F)C1=C([H])N([H])N=C1C(=O)N([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]1(OC(=O)\C(=C(\[H])C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C1([H])[H])C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)OC([H])([H])C(=O)C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C(=C([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H]
[H]N([H])C(C(=O)N([H])[C@@]([H])(C1=NN=NN1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=C(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(F)=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NN(C2=C1C([H])([H])[C@]1(C(=C2[H])C([H])([H])C([H])([H])C([H])([H])[C@]11O[C@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(O1)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@@]([H])(C1=C(N(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C(F)(F)F
NC(=O)C1=CC=C2C3=C(CCOC2=C1)C=C(S3)C1=NC=NN1CC(F)(F)F
[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C(N=C2N1C(=O)C(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])=C(N2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(SC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C(=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C([H])([H])C([H])([H])C2=C1C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])C([H])([H])F)C([H])([H])C1([H])[H])C([H])=C2[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])C4=C(C([H])=C([H])C(=O)C(Cl)=C4[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]ON([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(\C(=N/C#N)N1C([H])([H])C([H])([H])C(=C2C3=C(C([H])=C(Br)C([H])=N3)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]OC(=O)[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=NN=C2CCC3=C(C=C(Cl)C(=C3)C3=CN=CC4=CC=CC=C34)N12
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])SC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])SC([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C(C#N)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]2(O[H])C(=O)C([H])([H])SC2=NC3=C(N2[H])C([H])=C([H])C([H])=C3[H])[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C(=O)C([H])=C([H])[C@]3(C([H])([H])[H])[C@@]12[H]
[H]N(C1=NC([H])=NC2=C([H])C([H])=C(C#CC3=C([H])C([H])=C([H])S3)C([H])=C12)C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]C1=NC([H])=C2N=C(N(C2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(ON=C1C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC(=NC([H])=C1[N+]([O-])=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC(=O)C1=C([H])C(N([H])C2=C([H])\C(=N/S(=O)(=O)C3=C(C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3C2=O)=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)C([H])([H])N1C(=O)[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C(=O)N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])[C@@]([H])(C([H])([H])OC2=C([H])C([H])=C3C([H])=C([H])C([H])=NC3=C2[H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])[H])[C@@]([H])(N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]C1=C(Cl)C(=C([H])C(Cl)=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C2([H])[H]
[H]N(C(=O)C1(N([H])C(=O)C(F)(F)F)C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C(Cl)=C([H])C(Cl)=C1C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])S(=O)(=O)N(C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C2=C(OC3=C([H])C([H])=C([H])C([H])=C23)C(=O)N(C1=S)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1
[H]N([H])C1=C([H])C([H])=C(C([H])=C1C(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])N=C([H])C(OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])=C1[H]
[H]N(C(=O)C1=C2N(C([H])=C1[H])[C@]([H])(SC2([H])[H])C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C1=C([H])C(C#N)=C(Cl)C([H])=C1N(C([H])([H])C1([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C1=NN=NN1C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=NC([H])=C(C(=C2C(=N1)N([H])[H])C([H])([H])[H])C([H])([H])N([H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C([H])N=C2SC([H])=C([H])N2C1=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=C1C([H])([H])[C@@]([H])(N(C(=O)C1=NC([H])=C(OC([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])=C1[H])C([H])([H])[H])C2([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1C(=O)O[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1O[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C2=C([H])C(=C([H])C([H])=C2N=C1C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)[C@@]([H])(C2=C([H])SC(=N2)N([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])N(C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N2C([H])=C(C3=C([H])C([H])=C([H])N=C23)S(=O)(=O)C2=C(F)C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N1C2=C([H])C(OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2C2=C1C(=NC([H])=C2[H])C([H])([H])[H]
[H]N1N=C(C2=NN=C3SC([H])([H])C(=NN23)C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C2=C1C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H]
[H]N(C1=C([H])C2=C(N([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=NC2=C1SC(=C2[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])N=C(C([H])=C1[H])N(C1=C([H])C(OC([H])([H])C(F)(F)F)=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(F)=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]OC1=C2N([H])C(=NS(=O)(=O)C2=C([H])C(Cl)=C1[H])N([H])C1=C(Br)C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C([H])=C([H])N([H])C1=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C#CC([H])([H])N(C(=O)[C@@]1(C2=C([H])SC([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])[H])C([H])([H])C#C[H]
[H]N1C2=C([H])C([H])=C(Cl)C([H])=C2C(C(=O)C(=O)N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])=C1C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C(=O)O[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C([H])([H])C([H])=O)C([H])([H])C(=O)O[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C(=N\C1=C([H])C([H])=C(Br)C([H])=C1[H])\C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=S)N([H])[C@]1([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]1([H])OC(=O)C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2Br)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N1C(=S)S\C(=C(/[H])\C(\[H])=C2\N(C3=C([H])C([H])=C([H])C([H])=C3C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=O
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C#CC2=C([H])C(F)=NC([H])=C2[H])C([H])=C1[H]
[H]OC1=C2N(N=C(C2=NC(=N1)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C(F)C([H])=C([H])C([H])=C1F
[H][C@]12CC[C@]([H])(C[C@H](C1)OC1=CC=CC(=C1)C(N)=O)N2CC1=CC=C(C)O1
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C1=NN(C(=O)N21)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C([H])([H])C1=C([H])N=C2N=C(N=C(N([H])[H])C2=N1)N([H])[H])C([H])([H])C([H])([H])[H])C(=O)O[H]
[H]C1=NC2=C(C([H])=C([H])C(=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]3([H])C4=C(C#N)C([H])=C([H])C([H])=C4C([H])([H])C([H])([H])[C@]23[H])C1([H])[H]
[H]N(C(=O)C1=NOC(=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1SC([H])([H])[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C(N2N=C(OC([H])([H])[H])C(N(C([H])([H])C([H])([H])[H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2S1)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]N1C([H])([H])[C@@]2([H])C([H])=C(C3=C([H])N=C([H])C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])=C3[H])C([H])([H])[C@@]([H])(C1([H])[H])C2([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2C([H])([H])OC([H])([H])C#C[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C2=C(N([H])C3=C2C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]N([H])C1=C(N(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC(=O)C(N1C(C2=CC=C(Cl)C=C2)C(=S)NC2=CC(=CC=C2C1=O)C(F)(F)F)C1=CC=C(Cl)C=C1
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C2N=C(C([H])=C(N2N=C1[S@](=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])O[H])C([H])([H])C([H])([H])C(=O)N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])O[H])C([H])([H])C(=O)O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])O[H]
[H]C1=C2C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=NC1=C2C([H])=C([H])C([H])=C1[H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(S1)N([H])C1=C([H])C(=NC(=N1)C([H])([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(N2C([H])=C(Cl)C([H])=C(Cl)C2=N1)[C@@]([H])(C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(C([H])=C(Cl)C([H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N([H])C(=O)C1=C([H])C(N([H])C2=NC(=C([H])C([H])=N2)C2=C(N=C(N2[H])C(F)(F)F)C2=C([H])C(N([H])C(=O)C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC(=O)C(=O)N1\C(=N\N([H])C([H])([H])C(=O)O[H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N(C([H])([H])[H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1OC1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C2=NN=C(C(=O)N2C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C3=C(C([H])=C2[H])C2=C([H])C([H])=C(O[C@@]4([H])C([H])([H])N([H])C([H])([H])C4([H])[H])C([H])=C2C3=O)C1([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@]2(O[H])C(=O)C([H])([H])SC2=C([H])C([H])=C([H])C([H])=N2)[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C(=O)C([H])=C([H])[C@]3(C([H])([H])[H])[C@@]12[H]
[H]OC([H])([H])[C@@]([H])(N([H])C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C([H])([H])C1=C([H])C([H])=C(N([H])C(=N[H])N([H])[H])C([H])=C1[H])P(=O)(OC1=C([H])C([H])=C([H])C([H])=C1[H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@](C1=C([H])C([H])=C(Cl)C([H])=N1)(C1=C([H])C(F)=C([H])C(OC(F)(F)C([H])(F)F)=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])C1(F)F
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN2C(=NN=C2C([H])([H])OC2=C([H])C([H])=NC3=C2C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])\N=C(/[H])C1=C(N=C2SC(=C(N12)C([H])([H])[H])C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)N(C1=NC([H])=NC(N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H])C1=C(Cl)C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1Cl
[H]OC1=C([H])C(=C([H])C([H])=C1Cl)C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=NC([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C(=O)C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C(N2N=C(OC([H])([H])[H])C(N(C([H])(C([H])([H])[H])C([H])([H])[H])C3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C2S1)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]N(C1=NC([H])([H])C2=C1C([H])([H])N(C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C1=C2C([H])=C(SC2=NC([H])=N1)C([H])([H])[H]
[H]N(C1=C2C([H])=C(OC([H])([H])[H])C([H])=C([H])C2=NC2=C1C([H])=C([H])C(Cl)=C2[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C2S[C@@]([H])(C([H])([H])[H])C([H])([H])C3=C2C(=C([H])C([H])=C3OC([H])([H])C2=C([H])C([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C#CC2=C([H])C3=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])=C3C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(N1C([H])([H])C([H])([H])N([H])C2=C(C([H])=C([H])C(O[H])=C2[H])S1(=O)=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C([H])C(=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C(=N1)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1=NC([H])=C(C#CC2=C([H])C(=C([H])C([H])=C2C([H])([H])[H])C(=O)N([H])C2=C([H])C(=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(F)(F)F)N1C([H])([H])[H]
[H]OC(C1=C([H])SC(=C1[H])C([H])([H])[H])(C1=C([H])SC(=C1[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[N+]2(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C(N2[H])C2=C([H])N=C([H])C(=N2)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=N1)C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1C1=N[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])N1C(=O)N2C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)O[H])C([H])([H])S[H])C([H])([H])S[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])S[H])C([H])([H])O[H])C([H])([H])S[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3C(OC([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])N2C2=C(C([H])=C([H])N=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C(=O)N([H])C2=C([H])C([H])=C(F)C([H])=C2[H])[C@@]([H])(C(=O)N([H])C2=C(F)C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)C([H])([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])OC([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=NC2=C1C([H])([H])OC2([H])[H]
[H]N(C(=O)C1=C([H])N=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C(C#N)=C([H])C([H])=C12)C([H])([H])C([H])([H])[C@]1(N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C1=N[C@@](C(=O)N1C([H])([H])[H])(C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=C([H])N=C1[H])C1=C([H])C(=NC([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)C(\[H])=C(/[H])C(=O)OC([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(N2N=C3C(N=C([H])N(N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C3=O)=C2C2=C([H])C([H])=C(Cl)C([H])=C2[H])C(Cl)=C1[H]
[H]N(C(=O)OC([H])([H])C1=C(F)C([H])=C([H])C([H])=C1Cl)C1=C(ON=C1C1=C(Cl)C([H])=C([H])C([H])=C1F)C([H])([H])[H]
[H]N([H])C1=C(C([H])=C(S1)C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])S1
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])SC([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]1(C([H])([H])N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])[H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C3C(=C1[H])N(N=C3C([H])([H])N(C2=O)[C@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])N=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(F)N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)C([H])([H])C1=C([H])C(Cl)=C(OC2=C([H])C([H])=C(O[H])C([H])=C2[H])C(Cl)=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])C2=NC(=C([H])C([H])=N2)C2=C(N=C(S2)N([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])N([C@]([H])(C4=C([H])C([H])=C(C([H])=C4[H])S(=O)(=O)C4=C([H])C([H])=C5OC([H])([H])OC5=C4[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C3([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])N=C(C([H])=N1)C1=NN=C(SC([H])([H])C2=C(Br)C([H])=C([H])C([H])=C2[H])S1
[H]N1C(=NC2=C(C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N(C(=O)N([H])C2=O)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C([H])C([H])=C([H])C([H])=C12)N(C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(C3=C1C([H])=C([H])C(O[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])=C3[H])C([H])([H])C([H])([H])SC2([H])[H]
[H]N([H])C1=C(C([H])=C([H])C(Cl)=N1)C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])N(C3=NC([H])=C(N=C3C([H])([H])[H])C(=O)N([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])[C@@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=NC([H])=N2)N1C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C([H])N=C1[H])C1=NC([H])=C2N([H])N=C(C2=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(\N=C(\C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C(=O)N([H])C1=NN([H])C(=S)S1
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])N([H])N=C1C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]O[C@]1(C(=O)N([H])[C@@]([H])(C2=C(F)C([H])=C(C([H])=N2)C2=C([H])C(Cl)=C([H])C(F)=C2C2=NN(N=N2)C([H])([H])[H])C([H])([H])[H])C([H])([H])[S@@](=O)C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(O[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C(\[H])=C(/[H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])O[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[H])C([H])([H])O[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])C(=O)O[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])S[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=NC([H])=C([H])C(OC2=C([H])C([H])=C3N(C(=NC3=C2[H])N([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C(C#N)C(=C(S1)C(=O)N(C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)O1)C1=C([H])C([H])=C([H])C(=C1N1C([H])([H])C([H])([H])C2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1=C(N([H])C2=C(Cl)C(=C([H])C([H])=C2Cl)C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]\C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])=C1/C(=NC([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C(Br)=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=C(C2=C(N=C([H])N=C12)N([H])C([H])([H])C([H])([H])C(=O)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@]2(O[H])C(=O)C([H])([H])SC2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C4=C(C([H])=NN4C4([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]12[H]
[H]N(C(=O)OC1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)N([H])[C@]2([H])C([H])([H])C([H])([H])C3=C(C([H])=C([H])C(F)=C3[H])[C@@]2([H])C([H])([H])C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N=C([H])S1)N([H])C([H])([H])C1=C([H])C([H])=NC(=C1[H])C(=O)N([H])C([H])([H])[H])C1=C([H])C2=C(OC(F)(F)C(F)(F)O2)C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])N([H])[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])N(C(=O)C([H])([H])[C@@]([H])(SC(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])C2=C([H])N([H])N=C2C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)[C@]1([H])N(N=C(C2=C(N=C(S2)C([H])([H])[H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])N(N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C(OC2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(OC([H])([H])C([H])([H])OC2=NC([H])=C(C([H])=N2)C([H])([H])[H])=NC([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C(C([H])=C2[H])C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C(Cl)=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN=C(O1)N([H])C1=C([H])C(F)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])N(C(=N1)C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)O[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])C2([H])[H])[C@]([H])(C(=O)C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NN(C([H])=C1C1=C([H])C([H])=NC2=C([H])C(OC(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N=C(S1)[C@](OC([H])([H])[H])(C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])=C2[H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=C([H])C([H])([H])C2([H])[H])C(=O)C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=NC(=C([H])C([H])=N1)C1=C(N=C([H])N1C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C([H])=N\C(=N/C2=C([H])C(Cl)=C(F)C([H])=C2[H])C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]N(C(=O)C1=C([H])C([H])=C(O1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1N1C([H])([H])C([H])([H])C2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(SC([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(N2C([H])=C(C([H])=C(Cl)C2=N1)C(F)(F)F)C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)C([H])([H])C([H])([H])C2=C1N=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C(C(Cl)=C([H])C([H])=C3[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])=C2[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2OC([H])([H])C1=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C([H])N=C(C(=N1)C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])P([O-])(=O)OC([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N1N=C(C(=C1[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=O)N2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C1=NC2=C([H])C(=C([H])C([H])=C2N1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C(C(=O)N1C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])[C@@]2([H])N(C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=NC4=C(C(=NN34)C3=C([H])C([H])=NC([H])=C3[H])C3=C([H])C(OC([H])([H])[H])=C(F)C([H])=C3[H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C(O1)N([H])C1=C([H])C2=C(C([H])=C1[H])C(C#N)=C([H])N2C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(C(=O)N2C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])N1N=C(C([H])=C1C([H])([H])[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(OC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])[N@+]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C([H])=C2C(=O)OC(=NC2=C1[H])N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])=C([H])C(=O)N2C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1N1N=C(N=C1C1([H])C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(F)C([H])=C2F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1C(OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])=NN2[H])C1=C([H])C([H])=C(OC([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C(Cl)=C1[H]
[H]O[C@](C1=C([H])C2=C([H])C(=C(C([H])=C2N1[H])C(F)(F)F)[N+]([O-])=O)(C([H])([H])[H])C([H])([H])OC(=O)C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]C1=C([H])N2C(=C1[H])C(=NC1=C2C(=C([H])C([H])=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C(=NC2=C(N=C1C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H][C@]12C(=O)N(C(=O)[C@@]1([H])[C@@]1(C)O[C@]2(C)C(=O)[N](O)(C(C)C)C1=O)C1=CC=C(C#N)C(=C1)C(F)(F)F
[H]N(C(=O)C(\C#N)=C(/[H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
CN1CCN(CC1)[C@@H]1CC[C@@H](CC1)N1N=C(C2=C1N=CN=C2N)C1=CC=C(NC2=NC3=C(O2)C(Cl)=CC(Cl)=C3)C=C1
[H]O\N=C1/C(=O)N(C2=C([H])C([H])=C([H])C(=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C2OC([H])([H])OC([H])([H])C2=C([H])C(F)=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])N1C([H])([H])[C@@]2([H])C(=O)N(C3=C([H])C([H])=C(OC(F)(F)F)C([H])=C3[H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N(C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1N=C(C(=C1[H])C1=C([H])C2=C([H])C([H])=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(F)=C(F)C(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])=C1[H]
[H]N(C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN2C(=N1)C1=C(N=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=C(N([H])C(=O)N([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])N([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(N([H])C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2N=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C(C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])C(=C23)C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(OC([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(=N1)N1C([H])([H])C([H])([H])C([H])(OC([H])([H])C([H])([H])O[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@@]1([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])N([H])C([H])([H])C2=C([H])C(Br)=C([H])C([H])=C2C1([H])[H]
[H]\C(=C(\[H])C([H])([H])[C@]([H])(C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])[C@@]([H])(N(C(=O)[C@]1([H])OC(O[C@]1([H])C([O-])=O)(C([O-])=O)C([O-])=O)C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])[H])C1=NC2=C(O1)C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C([H])([H])C1=C([H])C(OC2=C(N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])[N@]2C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C([H])C(C#N)=C([H])C(=C1[H])C(=O)C([H])([H])Br
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C2=C([H])C([H])=NC(=N2)N([H])C(=O)C([H])([H])[N+]2=C(C([H])=C(C([H])=C2C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])OC([H])([H])[H]
[H]OC(=O)[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@@]([H])(OC(=S)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C1=NC3=C([H])C([H])=C([H])C([H])=C3S1)C2([H])[H]
[H]OC1(C2=NC(=C(N2[H])C2=C([H])C([H])=NC(N([H])[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])C([H])([H])[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(OS(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2OC(=O)C(=C(C2=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=[N+](C([H])=C(S1)C([H])([H])[H])C([H])([H])C1=C([H])C(OP([O-])(=O)OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C1=C2C([H])=C(N([H])C2=NC([H])=N1)C1=C([H])C([H])=C(F)C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C(C([H])=NC2=C1C([H])=NN2C([H])([H])C([H])([H])[H])C(=O)OC([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C([H])N1[H])C1=C(C([H])=C(OC([H])([H])[H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1F)C1=C([H])C(C2=C([H])C([H])=NN2C([H])([H])[H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])[C@]3(C4=C(C([H])=C(Br)C([H])=C4[H])C([H])([H])C3([H])[H])C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])C([H])=C([H])C([H])([H])N2C(=O)C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(N([H])C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]([H])(N1N=C(C([H])=C(C1=O)C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)C2=C(C([H])=C([H])[N+]([O-])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)O[C@]1([H])C([H])([H])OC(=O)N=C=NC(=O)OC([H])([H])C([H])([H])[H]
[H]N1C(=O)N(C2=C(N=C(SC3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])C1([H])[H])C1=C(F)C([H])=C([H])C([H])=C1Cl
[H]O[C@@]([H])([C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]C1=C2OC(=O)C([H])([H])[C@]([H])(C3=C([H])C(OC([H])([H])[H])=C(OC(=O)C([H])([H])[H])C(OC([H])([H])[H])=C3[H])C2=C([H])C2=C1OC([H])([H])O2
[H]N(C(=O)C([H])([H])SC1=NC([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C(=O)N1C1=C([H])C([H])=C(N=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C(C(=O)C([H])([H])C([H])([H])N21)C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(SC([H])([H])[H])N=N2)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N(C#N)C1=NN=C(S1)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C(Cl)C([H])=C([H])C(=C1Cl)C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(Br)S2)=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2S(=O)(=O)C([H])([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])N(C(=NC([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(N([H])C(=O)N([H])[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2=C3C([H])=C([H])C([H])=C([H])C3=NC(=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)N(C2=C(C(=C(S2)C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]C([H])=C([H])C([H])([H])N(C(=O)OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]([H])(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C2=C(N([H])N=C2[H])C([H])=C1[H]
[H]C1=C([H])C(C#CC([H])([H])OC2=NSN=C2[C@]23C([H])([H])[N@@]4C([H])([H])[C@@]2([H])[C@@]3([H])C4([H])[H])=C([H])C([H])=C1Cl
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C(F)(F)F)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])C1=NC2=C(N1[H])C(=C([H])C([H])=C2[H])C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N([H])C1=N[C@@]([H])(N(C(=N1)N([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C([H])C(OC2=C([H])C(Cl)=C([H])C(Cl)=C2[H])=C([H])C([H])=C1[H]
[H]N(C1=C2C([H])=C(C(OC([H])([H])[H])=C([H])C2=NC([H])=N1)[N+]([O-])=O)C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]\C(C1=C([H])C([H])=C([H])C([H])=C1[H])=C1\C([H])([H])N2C3([H])C([H])([H])C([H])([H])[C@]2([H])[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@]1([H])C3([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C#N)N1C(=NC(=C1C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])N=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C2C([H])=C([H])C(=C([H])C2=NC([H])=N1)C([H])([H])N1C([H])([H])C(=O)N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(Cl)C([H])=C2[H]
[H]N1C(=C([H])C2=C1C(F)=C([H])C(Cl)=C2[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])C([H])([H])[C@@](C1=O)(C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]\C(=N/C1=C(C#N)C(C2=C([H])C([H])=C([H])O2)=C(O1)C1=C([H])C([H])=C([H])O1)C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=N1)[C@]([H])(C#N)N1C([H])([H])C([H])([H])N(C(=O)C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC([H])=C(C([H])=C([H])[H])C(=O)N2C([H])([H])C2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=N[C@@](C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])C(=O)C2=NC([H])=C(OC([H])([H])C([H])([H])C#CC([H])([H])[H])N=C2[H])(C([H])([H])[H])C([H])([H])C([H])([H])S1
[H][C@@]12C[C@H](O)CC[C@@]1([H])C(C)(C)OC1=C2C(O)=CC(=C1)C1(CCCCCC)SCCS1
[H]N(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C2=C1OC(=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC1=C(Cl)C([H])=C([H])C(=C1[H])C1=NN(C2=C1C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]SC([H])([H])[C@]1(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C(F)(F)F
[H]N1C([H])([H])C(=C([H])C([H])([H])C1([H])[H])C1=NN(N=C1[H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)S[C@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=N2)C([H])=C1[H]
FC(F)(F)C1=CC=CC(SC2=NN3C(C=C2)=NN=C3C2=C(Br)C=CS2)=C1
[H]C1=C(Cl)C([H])=C([H])C(OC([H])([H])[C@@]2(C([H])([H])[H])C([H])([H])N(C(=O)C3([H])C([H])([H])C([H])([H])N(C4=C([H])C([H])=C(C#N)C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=N1
[H]N(C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2C(N([H])C([H])=C2C2=C([H])N=C([H])O2)=C1[H]
COCCN(CC1CCOCC1)C1=C2C=CC=C(N2N=C1SC)C1=C(OC)C=C(COC)C=C1OC
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@]1(OC(=O)C(=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NOC(=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H])C(F)(F)F
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@]([H])(OC1=C(C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C2=C(C3=C([H])C([H])=C([H])C([H])=C3N2S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C(C2=C(N([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C1=C2C([H])=C(SC2=NC([H])=C1C#N)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])O[H]
[H]C1=C([H])C2=C([H])C([H])=C([H])C(=C2S1)C([H])([H])N(N1C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=C2OC([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(S[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(N(C2=NC([H])=C([H])C(=N2)C2=C([H])N=C3C([H])=C([H])C([H])=C([H])N23)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(\SC1=C([H])C([H])=C(Cl)C([H])=C1[H])=C(\C#N)/C(/C#N)=C(/SC1=C([H])C([H])=C(Cl)C([H])=C1[H])N([H])[H]
[H]N(C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C(=O)N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]1([H])N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[C@@]([H])(N([H])C(=O)N([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N([H])C2=C(C#N)C([H])=NN3C([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C(=C23)C([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])\N=C(/[H])C1=C(N=C2C([H])=C([H])C([H])=C([H])N12)C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1OC([H])([H])[H])[N+]([O-])=O
[H]OC1=C(OC([H])([H])[H])C([H])=C2C(=C1[H])[C@]1([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)[C@@]2([H])N([H])C(=O)N([H])C(=O)C2([H])[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C(=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC(SC([H])([H])[H])=C1C(=O)N1N=NN=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=[N+](C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C([H])=C(F)C(F)=C1C1=C([H])C(Cl)=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C2C(=O)C(OC(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])=C(OC2=C1[H])C1=C([H])C(O[H])=C(O[H])C([H])=C1[H]
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C1(C2=C([H])C(=C([H])C([H])=N2)C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)N([H])C1=C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])([H])[C@]4(OC(=O)N(C4=O)C([H])([H])C([H])([H])[H])C3([H])[H])C([H])([H])C2([H])[H])C2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]N(C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
NC(=O)C(=O)N1CCC2=C(C1)C(=NN2CCCN1CCOCC1)C1=CC(C#CC2=CC=C(CNCC3=CC=C(Cl)C=C3)C=C2)=C(Cl)C=C1
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C2OC3=C(OC(=O)C2=C1OC([H])([H])[H])C([H])=C(C([H])=C3OC(=O)N1C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])ON2C(=O)[C@]3([H])[C@]([H])(C2=O)[C@]2(OC(=O)C([H])([H])[H])C([H])=C(C([H])([H])[H])[C@@]3([H])[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(N1C([H])([H])C([H])([H])N([H])C2=C(C([H])=C([H])C(OC([H])([H])C3=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C3[H])=C2[H])S1(=O)=O)C([H])([H])C([H])([H])C(=O)OC([H])([H])[H]
[H]OC(=O)C([H])([H])N(C(=S)C1=C([H])C([H])=C([H])C2=C(C(OC([H])([H])[H])=C([H])C([H])=C12)C(F)(F)F)C([H])([H])[H]
[H]C1=C2N(C(=O)[C@]([H])(C([H])([H])C(=O)N3C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])[C@@]2(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]C1=NC2=C(N=C(C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C(F)(F)F)C#N
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C([H])N=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])[H]
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])=C1[H])C([H])([H])N1C(=NC2=C([H])C([H])=C(C([H])=C12)N(C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C2C(=C1[H])[C@@]1([H])N(C([H])([H])C3=C(C([H])=C([H])C(OC([H])([H])[H])=C3O[H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(=O)C1=C([H])C(OC(=O)C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N1C(=O)N(C([H])([H])C1(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])[N@+](C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])C([H])([H])OC([H])([H])[H])C1([H])[H]
[H]OC(=O)C1=C([H])C(N([H])C2=NN(C(=O)C3=C(F)C([H])=C([H])C([H])=C3F)C(=N2)N([H])[H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(OC2=C(OC([H])([H])[H])C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(F)=C(C(=C1[H])C1=C([H])C2=C(C([H])=C1[H])C1(C(=O)N2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C#CC([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1N1C([H])([H])C([H])([H])C2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])F)C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]1([H])C([H])([H])N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)C1([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])N(C([H])([H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(OC([H])([H])[C@@]2([H])C([H])([H])N(C(=O)C2(C([H])([H])[H])C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]3([H])[C@]([H])(C(=O)OC([H])([H])C([H])([H])[H])[C@@]3([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1C#N
[H]C1=C([H])C(=C([H])C([H])=C1Br)[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C(F)=C1C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(S1)N([H])C1=C([H])C(=NC(=N1)C([H])([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=N1)C1=NOC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC1=C([H])C(N([H])C(=O)[C@]2([H])C([H])([H])C([H])([H])[C@]3([H])[C@]4([H])C([H])([H])C([H])([H])[C@@]5([H])N([H])C(=O)C([H])=C([H])[C@]5(C([H])([H])[H])[C@@]4([H])C([H])([H])C([H])([H])[C@]23C([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C(N=NN1C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@]([H])(OC1=C([H])C([H])=C([H])C2=NC([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])N([H])C3=C2N=C(N([H])[H])N([H])C3=O)C([H])([H])[C@]1([H])O[H]
[H]OC1=C([H])C([H])=C(O[H])C(=C1[H])C([H])([H])N([H])C1=C([H])C([H])=C(O[H])C(=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C1=C([H])C([H])=C(F)C(Cl)=C1[H])C1=C2C([H])=C(N([H])C([H])([H])C([H])([H])C3=C([H])N([H])C([H])=N3)C([H])=C(Cl)C2=NC([H])=C1C#N
[H]N(C(=O)C([H])([H])[S@](=O)C([H])([H])C1=C(OC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C(=C1[H])N(C([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1(C#N)C([H])([H])C1([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C1=NS(=O)(=O)C2=C([H])C(F)=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])C(=O)C([H])([H])C([H])([H])[C@@]4(N([H])C(=O)C(Cl)=C([H])[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C2=C(N=C(N=C2C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N([H])C(=O)C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])N(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([O-])=O
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(N2C([H])=C(Cl)C([H])=C(Cl)C2=N1)C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C1([H])[H]
[H]C1=C(N(C(=C1[H])C([H])([H])C(=O)N(C1=C([H])C([H])=C(Cl)C(=C1Cl)C([H])([H])OC1=C2N=C(C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N(C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(ON=C1C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C(=O)N([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C(C(=O)O[H])[C@@]([H])(C2=C(Cl)C([H])=C([H])C([H])=C2[H])C(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])=C(N1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])SC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=NC(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=NC2=C(N=NN2C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(=N1)C1=C([H])C([H])=C([H])O1
CCCCC1CCN(CCCC(=O)C2=C(C)C=CC=C2)CC1
[H]OC(=O)C1=C([H])C([H])=C([H])N1[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=C([H])N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC(C)(C)NC(=O)NCCN1CCN(CC(=O)NC2=CC(Cl)=CC(Cl)=C2)CC1
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2N=C([H])C(=N2)C([H])([H])C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H]
[H]O[C@]1([H])C2=C(OC([H])([H])[C@]1([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])=C([H])C(OC([H])([H])C1=C([H])C([H])=C(C(=N1)C([H])([H])[H])[N+]([O-])=O)=C2[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC([H])=NC(N([H])C3([H])C([H])([H])C3([H])[H])=C2[H])C([H])([H])[C@]1([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C(I)=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)[C@]([H])(O[H])C([H])([H])[H])C([H])([H])O[H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C2=NOC(=C2C(=O)N(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]OC(=O)[C@@]([H])(C#N)[C@]1([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C12)[N+]([O-])=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])C([H])([H])N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])[C@@]([H])(N2C4=C(N=C2C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C4[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(OC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C2N=C([H])N([H])C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]12C([H])([H])C([H])([H])[C@@](C3=NC4=C(N3[H])C3=N[C@]([H])(C5=C([H])C([H])=C([H])C([H])=C5[H])C([H])([H])N3C(=O)N4C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
CC[C@@H](CO)Nc1ncc(Cl)c(n1)N1CCN(CC1)C(=O)N[C@H](CO)c1cccc(Cl)c1
[H]OC1=C([H])C([H])=C(C([H])=C1Cl)C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(N([H])C2=NC([H])=NC(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C2C#N)=C1[H])C([H])([H])[H])C1=NOC([H])=C1[H]
[H]N([H])C1=NC(=C([H])C(=N1)N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C(N=C(N1C([H])([H])[H])C([H])([H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C(=NN12)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1C1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])O[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C(=O)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C([H])=C(S2)C(=O)N([H])C([H])([H])C([H])([H])[H])C(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])[C@@]2([H])C1=NC([H])=C([H])N1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C2C(SC3=C(Cl)C([H])=C(F)C([H])=C3[H])=C([H])N([H])C2=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]N(C(=O)C1=C([H])C(OC2=C(F)C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=C([H])C(=O)N(C2=C1C([H])=NN2C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])OC1=C2OC([H])([H])C([H])([H])C([H])([H])C2=C([H])C(F)=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)[C@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=N[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])SC([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])SC1(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C(\[H])=C(/[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=NC2=C([H])C([H])=C(C#CC([H])([H])N([H])C(=O)C3=C([H])C([H])=C([H])N(C3=O)C([H])([H])C3=C([H])C([H])=C(F)C(F)=C3[H])C([H])=C12
[H]C1=C([H])C(Cl)=C(C(Cl)=C1[H])C1=C2C([H])=C([H])C(SC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])=NN2C([H])=NC1=O
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C([H])(C1=C([H])C([H])=C(OC([H])(F)F)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])(F)F)C([H])=C1[H]
OC[C@H]1O[C@@H](CC(=O)\C=C\C2=CC(O)=CC=C2)[C@H](O)[C@@H](O)[C@H]1O
[H]O[C@]1([H])[C@]([H])(O[H])[C@]([H])(O[C@@]1([H])N1C([H])=C([H])\C(=N\OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])N([H])C1=O)C([H])([H])O[P@](=O)(O[H])O[P@](=O)(O[H])OP(=O)(O[H])O[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[N+]1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N(C(=O)O[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@](N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C(N([H])[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OP(=O)(O[H])O[H])C([H])=C1[H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2C(=O)N(C(=O)N([H])C2=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[N+]([O-])=O)S(=O)(=O)N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)C([H])([H])S[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NOC2=C([H])C([H])=C(C([H])=C12)N1N=C(C([H])=C1C(=O)N1C2=C(C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]OC(=O)[C@@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C(\[H])=C(/[H])C#CC2=C([H])C(C#C\C([H])=C(/[H])C([H])([H])OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])[H])C(=O)O[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=C([H])N=C([H])C(=C1[H])C1=C([H])N2C(=NC([H])=C2N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
CCCCCCCN(CC1=CC=C(C=C1)N(CC)CC)C(=O)C1=CC=C(C=C1)N(C)C
[H]N(C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)C1=C([H])C([H])=C(O1)C([H])([H])OC([H])([H])C([H])([H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C(C(C2=C3N=C(N=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C3=NN2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])C2=C([H])C([H])=NN2C([H])([H])C1([H])[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N([H])[C@](C1=C([H])C([H])=C(Cl)C([H])=N1)(C1=C([H])C(F)=C([H])C(OC(F)(F)C([H])(F)F)=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])N(C(=O)C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C([H])C(N([H])[C@@]([H])(C(=O)N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(N([H])[H])=C2[H])C2=C(F)C(OC([H])([H])C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])[H])=C2[H])=C([H])C([H])=C1C(=N[H])N([H])[H]
[H]N1C2=C([H])C(=C(C([H])=C2N=C(C2=C([H])C([H])=C([H])C(=C2[H])C2=C([H])C(=NC([H])=C2[H])C([H])([H])OC([H])([H])[H])C([H])([H])C1=O)C([H])([H])[H])C(F)(F)F
[H]N1C(=O)N(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N1C([H])=C(C([H])=C1C#N)C1=C([H])C([H])=C2N([H])C(=O)OC(C2=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C(=O)C1=C([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1Cl)C(=O)N([H])\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N([H])[C@@]2([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C1=C([H])N=C(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C(Cl)=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=NC2=C([H])C([H])=C(OC([H])([H])C([H])([H])OC(=O)C([H])([H])[N+]3=C(C([H])=C(C([H])=C3C([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])=C2S1
[H]N(\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(N2C([H])=C(C(=O)N([H])[H])C(=O)C3=C([H])C([H])=C(C([H])=C23)N2N=C([H])C([H])=C2[H])C(Cl)=C1[H]
[H]OC1=C(C2=C(N=O)C3=C([H])C([H])=C([H])C([H])=C3N2[H])C2=C(N1[H])C(Cl)=C([H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=C(C(=O)C([H])([H])[H])C(=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H]
[H]C1=C(N=NN1C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C([H])C2=C([H])C3=[N+](C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C31)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)OC([H])([H])[H]
[H]N1[C@]2(C([H])([H])N(C([H])([H])C(F)(F)F)S1(=O)=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C2=C(C([H])=C([H])C(\C([H])=C(/[H])C([H])([H])N3C([H])([H])C([H])([H])C([H])(C([H])([H])C3([H])[H])C(F)(F)F)=C2[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@]1([H])N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(O[H])=C(C2=C1C(=O)C([H])=C(O2)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]([H])(O[H])C([H])([H])N(C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C(C#N)=C2[H])C11C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N1C2=C([H])C(Br)=C([H])C([H])=C2N=C(C2=C([H])C([H])=C([H])C(=C2[H])N2C([H])=NC([H])=C2[H])C([H])([H])C1=O
[H]N1N=C(C([H])=C1C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]OC(=O)C1=C(C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2N([H])C(=O)C2=C([H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C([H])=C1[H])C(=O)O[H]
[H]N1C(=O)C(C2=C([H])N(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[H])=C(C1=O)C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(N([H])C2=C1C(=O)C([H])([H])C([H])([H])C2([H])[H])C(\[H])=C1/C(=O)N([H])C2=C([H])C([H])=C(C([H])=C12)S(=O)(=O)N([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(O[H])=C1OC1=C(C(F)=C([H])C([H])=C1[H])C([H])([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])O[C@]1([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])O[C@]21[H]
[H]OC(=O)C1=C([H])C([H])=C([H])N1C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C1([H])[H])C([H])([H])OC(=O)[C@@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]N(C(=O)C1=C(N=C(Cl)C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C#N)C([H])([H])C2=C([H])SC([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1(O[H])C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C(Cl)=C(N=C1[H])N1C([H])([H])C([H])([H])N(C2=NC3=C(N([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C(C([H])=C3N2[H])C(F)(F)F)[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N([H])C([H])([H])C(=O)C([H])([H])SC1=NC2=C(C(=C([H])S2)C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N1C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C1=C2C([H])=C([H])C([H])=C1[H])=C1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N([H])C1=C2C([H])=C(SC2=C(C([H])=N1)C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=C([H])C([H])=C3[H])C3=C2C([H])([H])C([H])([H])C2=C3C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N1C([H])=C([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])SC([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OP(=O)(O[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])C1(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C1(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N1C([H])=C(\C([H])=C(/[H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C(=O)N2C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC1=C([H])C(=C(N=C1[H])C1=C2N=C(C([H])=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N2N=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H])=C(S2)C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N([H])C(C(=O)N([H])[C@@]([H])(C1=NN(N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C#N)C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2[H])C1=O
O=C(NC1=CC=CC(=C1)C(=O)OCC1=CC=CC=C1)N(CCC(C1=CC=CC=C1)C1=CC=CC=C1)CCN1CCOCC1
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])[S@](=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C([H])C(=C(OC([H])([H])C2([H])C([H])([H])C2([H])[H])C1=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OP(=O)(O[H])O[H])C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C(=NN2C2=C([H])C([H])=C([H])C([H])=C2C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H]
[H]N1C(=O)N([H])C(=O)C(=C([H])C2=C([H])C([H])=C(O2)C2=C(C([H])=C([H])C(Cl)=C2[H])[N+]([O-])=O)C1=O
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N(C([H])([H])C([H])([H])Cl)C([H])([H])C([H])([H])Cl)C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
CN(C)C(=O)OC1=NOC2=CC=C(Cl)C=C12
[H]N([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])N([H])C2=C1C([H])=C(F)C([H])=C2[H]
[H]OC1=C(O[H])C2=C(C3=C(C(=O)C2=N[H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(O3)C([H])([H])[H])C(C([H])=O)=C1[H]
[H]N([H])C1=NC(N([H])[H])=C(C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]N(C([H])([H])[C@@]1([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C3=C([H])C([H])=NC([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(Cl)S1
[H]OC1=C(C(F)=C([H])C([H])=C1N([H])C(=N\C#N)\N([H])C1=C(Br)C([H])=C([H])C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=NN2C([H])=C([H])C(=C([H])C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C(F)(F)C1([H])[H])[N+]([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2[H])N2C(=O)N(N=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]S\C(=N/C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H])C(=O)C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(=N1)C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])N1N=C2N(C1=O)C1=C(N=C([H])C([H])=C1[H])N=C2N([H])[H]
[H]OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H])[N+]([O-])=O
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C(C([H])=C(O[H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]C1=NC(=C(O1)C1=C([H])N2C(=NN=C2C2([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C1=O
[H]N(C(=O)N([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])S(=O)(=O)N1C([H])([H])C([H])([H])C(=C2C3=NC([H])=C([H])C([H])=C3C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C2[H])=N1
[H]N1C([H])([H])[C@]2([H])N(C3=NC(=C([H])C([H])=C3C2([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C2N(C(=O)OC2=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC(=C1C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])N3C([H])=C(N=C23)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[N+]([O-])=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]1([H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C([H])([H])[C@]1([H])N([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N([H])C(=O)N(C([H])([H])C2=C([H])C([H])=C(OC3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])C([H])=C2[H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C(N([H])C1=O)C([H])=C([H])C([H])=C2[H]
[H]N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N1C([H])=C(C(=O)N=C1SC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])N(N=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C4C([H])=C(C([H])=C([H])C4=N3)C([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(SC3=C([H])C([H])=C(Cl)C([H])=C3[H])C3=C(OC([H])([H])[H])C([H])=C([H])N=C3N2C([H])([H])C([H])([H])C1([H])[H]
C1[C@H](NN=C1C1=C2C=CC=CC2=CC2=CC=CC=C12)C1=CC=CC=C1
[H]N(C(=O)C1=C([H])C([H])=C(O1)C#N)C1=C(C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C#N)C([H])([H])C1([H])[H])C1=C([H])C(=C(Br)C([H])=C1[H])C([H])([H])[H]
[H]ON(C([H])=O)[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])N1C(=O)N([H])C(C1=O)(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])[C@]1([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])N([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=NN([H])C3=C2C(=NC([H])=N3)N([H])C2=C([H])C([H])=C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[C@@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C2=C1OC1=C([H])C([H])=C([H])C([H])=C21
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C(N2C(=N1)N(C(=O)[C@@]2(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C(=O)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N1C(=O)N(C([H])([H])C([H])([H])C2=NC3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N3[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])N(C(=O)N([H])C2=C([H])C(Cl)=C(F)C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C(C#N)=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])I)[C@@]12C(=C([H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]3([H])C([H])([H])C([H])([H])C(=O)[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)N([H])C1=NN=C(S1)S(=O)(=O)N([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])C1=NN=C(S1)S(=O)(=O)N([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C(=C2C(=O)O1)C([H])([H])[H]
[H]C([H])=C(C([H])([H])[H])C([H])([H])N1C(=O)C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[C@@]([H])(N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])N([H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]C1=C([H])C(=C(C([H])=C1N1C(=O)N(C(=O)C1([H])[H])S(=O)(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])C#CN([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])C2=C([H])C(O[H])=C(C(=O)O2)C2=C(\C([H])=C(/[H])C3=C([H])C4=C(C(=O)O3)C3=C(C([H])=C(O[H])C(O[H])=C3[H])C(=O)O4)C([H])=C(O[H])C(O[H])=C2[H])C([H])=C1O[H]
[H]OC1=C2N([H])C(=O)C([H])=C([H])C2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC(=O)N([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C(N(N=N1)[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])C1=C([H])C([H])=C2N=C([H])C([H])=NC2=C1[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[C@]([H])(O[H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(OC([H])([H])C([H])([H])C(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])C1=C(C2=C([H])N=C(OC([H])([H])[H])N=C2[H])C(=C([H])C([H])=C1F)C([H])([H])[H]
[H]OC1=C2C([H])=C3OC([H])([H])OC3=C([H])C2=NC(=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C(Cl)N=C(N2[C@@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C2=NN=NN2[H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC([H])=C(C(=N1)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C2N([H])C([H])=NC2=C1[H]
[H]OC(=O)C(OC([H])([H])C1=C([H])N(N=N1)C([H])([H])C([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(Cl)=C([H])C([H])=C2N2C([H])=C([H])C([H])=C12)C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])S[C@]1([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]1([H])OC(=O)C([H])([H])[H]
[H]OC1=C(SC2=NC([H])=NN2[H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)O[C@]([H])(C([H])([H])[H])[C@@]1([H])C(=O)N(C(=O)C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(C([H])=C1C1=C([H])C([H])=C(F)N=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]1([H])C([H])([H])C2([H])[H]
OC1=C(O)C=C(CNC2=CC3=CC=CC=C3C=C2)C=C1
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C(C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C2C([H])=C([H])C(C([H])=C2[H])=[N+](C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=C1[H])S([O-])(=O)=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C(=O)N2C3=C(N([H])C(=O)C4=C([H])C([H])=C([H])C([H])=C24)C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H]
[H]N1C([H])([H])[C@]2([H])C([H])([H])[C@]2(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H][C@@]1(CCN(C1)C(=O)[C@@H](N)CC1=CC=C(O)C=C1)S(=O)(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O
[H]N([H])C1=NC2=C(C(SC3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)=C(N2[H])C([H])([H])[H])C(=O)N1[H]
[H]N(C1=NC2=C(S1)C([H])([H])C([H])([H])OC1=C2C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2N([H])C(=O)C([H])([H])C(=O)OC([H])([H])[H])=C([H])C([H])=C1C(=O)C([H])([H])[H]
[H]OC([H])([H])C1=C(N(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])F)C([H])([H])N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])[H]
[H]N([H])C(=O)C1(C(=O)N([H])[C@]2([H])C3=C(N(N=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)N(C3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C(C([H])=N2)C2=C([H])C([H])=C(N=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])N(C([H])([H])C2=C(Cl)C(F)=C([H])C([H])=C2F)C([H])([H])C1([H])[H]
[H]N(C1=C2C([H])=C([H])C([H])=C([H])C2=NC1=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=NC([H])=C([H])S1
[H]C1=C(N(C(=C1C(=O)C([H])([H])OC1=C(N=C(C([H])=C1[H])C([H])([H])[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]N(\N=C1/C(=O)N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C2([H])[H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]12C([H])([H])C([H])([H])[C@@]([H])(C(=C([H])[H])C([H])([H])[H])[C@]1([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1S[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])C1=C(S[H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(Br)=C1[H])C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)N(C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(\C1=C(ON=C1C([H])([H])[H])C([H])([H])[H])=C1/C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])OC([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N1[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(C(=O)OC([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])S1)C2([H])[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C(F)C([H])=C(F)C([H])=C1F)C([H])([H])OC([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3N(C([H])=C([H])C3=C2[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C2=C(C3=C(C([H])=C([H])C(Cl)=C3[H])N2C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C(C([H])=C([H])C(OC([H])([H])[H])=C1[H])N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(C([H])=C([H])[H])=C2OC(=NC2=C1[H])C1=C(F)C([H])=C(O[H])C([H])=C1F
[H]C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])N(C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])[N+]([O-])=O
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC(=C(C(=O)N2C([H])([H])C2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(OC([H])=C2[H])C([H])=N1)[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C(Cl)C([H])=C2C(=C1[H])N1C(=C(C(=O)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C([H])([H])[H]
[H]N([H])C(=NN([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)[C@]([H])(N([H])C(=O)N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])N([H])[H]
[H]N([H])C1=C2C(=NC3=C1C([H])=C([H])C(F)=C3[H])C1=C([H])C([H])=C([H])C([H])=C1C2([H])[H]
[H]N(C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C2C([H])=C(C(=O)N(C2=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])[C@@]([H])(C(=O)OC([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)N([H])[C@](C1=O)(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C([H])N=C2C([H])=C1[H])C([H])([H])N1C(=O)C2=C(C([H])=C([H])C(F)=C2[H])C1([H])[H]
[H]\C(=C(\[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]N([C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C(Cl)C([H])=C2N2C1=NN=C2C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])[N+]([O-])=O)C([H])([H])C1([H])[H])C(F)(F)F
CC1=C(SC2=C1C(=NC=N2)N1CCC(CC1)NCC(O)COC1=CC(CO)=C(O)C=C1)C1=CC=CC=C1
[H]N1C(=O)N(C([H])([H])[H])[C@@]2(C1=O)C([H])([H])C1=C(C([H])=C3N([H])C(=NC3=C1[H])C([H])([H])N1C(=O)N(C3=C1C([H])=C([H])C([H])=C3[H])C1=C([H])C([H])=C([H])C([H])=N1)C2([H])[H]
[H]N1C([H])([H])C([H])(OC2=C(OC([H])([H])[H])C([H])=C([H])C(=C2[H])C2=C(C(F)=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H]
[H]OC([H])([H])C1=NC(Br)=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(N([H])C(=O)C2=NN=C(O2)N([H])C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])Cl)C1=C([H])C(=C(S1)C1=NN=C2S\C(=C(\[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C(=NN12)C1=C([H])C(F)=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C(C#N)=C2C(F)=C(O[H])C([H])=C([H])C2=C1[H]
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C([H])=C(C([H])=C2[H])N2C(=O)C3=C(C(=NN3C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])N3N=NC([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(N=C([H])C([H])=C2N1[H])C1=C(Br)C(Br)=C(Br)N1[H]
[H]O[C@]([H])(C([H])([H])N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(OC([H])([H])[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N([H])\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C([H])C(C#CC([H])([H])N([H])C(=O)C3=C([H])N=C([H])N(C3=O)C([H])([H])C3=C([H])C([H])=C(F)C(F)=C3[H])=C([H])C([H])=C2N=C1[H]
[H]N(C(=O)C1=NC(=NO1)C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C(Cl)=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@@](C2=C([H])C(O[H])=C([H])C([H])=C2[H])(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])[H])C([H])([H])SC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=NC(=NC2=NN(C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C(C2=C(F)C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])=C([H])C([H])=C(C1=O)C1=C(OC([H])([H])[H])C([H])=C([H])C(F)=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=NS2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])N=N1
C[C@@H]1CN(CCN1)C1=CC=CC(=N1)C1=NNC2=C1C=CC=N2
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C1OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1C2=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])N([H])C(=O)\C([H])=C1/[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2N(C3=C(SC2=C1[H])C([H])=C([H])C(Cl)=C3[H])C([H])([H])C([H])([H])C([H])([H])[N+]([O-])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C2C([H])=NC([H])=C([H])C2=C1[H]
[H]N1C2=C([H])C3=NC(C#N)=C([H])C(=C3C([H])=C2C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])N=C([H])C([H])=C2C([H])([H])[H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)C([H])([H])O[C@@]1([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1N(C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])C2=C(OC3=C1C([H])=C(F)C([H])=C3[H])C([H])=C([H])C([H])=C2[H])C1=NC(=C([H])O1)C(F)(F)F
[H]N([H])C([H])([H])C(=O)O[C@]([H])(C([H])([H])[H])C([H])([H])OC1=C([H])N2N=C([H])N=C(OC3=C(F)C4=C(N([H])C(=C4[H])C([H])([H])[H])C([H])=C3[H])C2=C1C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=NC(=C(S1)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(C1=C([H])C2=C(N=C1[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C3C(=N2)N([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=N1
[H]OC(=O)[C@@]([H])(OC1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])[C@]1(N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN([H])C(N([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C([H])([H])C([H])([H])N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])[C@]([H])(N2C4=C(N=C2C([H])([H])[H])C([H])=C([H])C([H])=C4[H])C3([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C3=C([H])C([H])=C(O[H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])=C1\C(=O)\C(=C(\[H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N([H])C1=C(N([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1OC([H])([H])[H])[C@@]13C([H])([H])C4=C(C5=C(N4[H])C([H])=C([H])C([H])=C5[H])C([H])([H])[C@@]1(O[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C(F)C([H])=C(F)C([H])=C2[H])C1=O
[H]N(C(=O)C1=C([H])C([H])=C(N2N=C(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(Cl)=C2C([H])([H])[H])C(=C1[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2N(C([H])([H])C3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C([H])([H])C([H])([H])C2=C1[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]\C(=C(/C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@]([H])(C(\[H])=C(/[H])[C@@]2([H])[C@]([H])(C([H])=C([H])[C@@]3([H])C([H])([H])[C@]([H])(C(\[H])=C(/[H])C([H])([H])[H])C([H])([H])[C@]([H])(OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]23[H])C([H])([H])[H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C(=O)OC([H])([H])[H]
[H]O[C@]([H])(C1=NC(=NC2=C1SC([H])=C2[H])C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NN(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=C([H])N=C4C([H])=C([H])C([H])=C([H])C4=N3)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])C([H])=C([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])C([H])([H])[C@]([H])(Br)C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]12C([H])([H])C(=O)\C(=C(/[H])C3=C([H])C(Cl)=C(Cl)C([H])=C3[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C1([H])[H])C2([H])[H]
[H]OC([H])([H])C1=C(C([H])=C([H])S1)C1=C(C#N)C(N([H])[H])=C([H])C(=N1)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C1=NC(=NO1)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])N=C([H])C(=C1[H])S(=O)(=O)N(C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C(=O)C([H])([H])SC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(S2)C2=C(C([H])=C([H])C(O[H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])[C@]([H])(N([H])C(=O)C4=C([H])C([H])=NC([H])=C4C([H])([H])[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C(=C2C3=NC([H])=C(C#N)C([H])=C3C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1(C2=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C2[H])[C@@]2([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@@]12[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)C1(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2N=C(N3N=C([H])C([H])=N3)N(C2=NC(=N1)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@]12C([H])([H])[C@@]1([H])C([H])([H])N(C2([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]2(C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])SC([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=NC([H])=NC2=C1C(=NN2C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2F)C(F)(F)F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(=O)C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C2C(=N1)N(C(=O)C(F)=C2C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C1=NN=NN1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]O\N=C(/C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C2N=C(C([H])=C(C2=C1[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])N(C([H])=N1)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
CC1=C(Cl)C(C)=C2C(N)=C(SC2=N1)C(=O)NC1CCCCC1
O=C1CCCC2=C1N=C(OCCCN1CCCCC1)S2
[H]C1=C([H])C(=C([H])C(O[C@@]2([H])C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C2([H])[H])=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])N2C(=NN=C2C2=NC3=C(C([H])=C([H])C([H])=C3O[C@@]3([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3([H])F)C([H])=C2[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C2=NC(=NC([H])=C2C([H])([H])C1([H])[H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C2C([H])=C(C(=O)N(C2=N1)C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]N([H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])N(N=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])[C@]([H])(OC(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(N([H])C(=O)S2)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC(N([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C3N=C([H])N([H])C3=N2)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C([H])C([H])=C(C2=N1)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])P(=O)(O[H])O[H]
[H]C1=NN(C([H])=C1C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C(=O)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=C(C2=C1N=C([H])N=C2N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=NN2[C@@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C(C2=NC3=C(C([H])=C([H])C([H])=C3F)N2C([H])([H])[H])=C1C([H])([H])[H]
[H]O[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])S2(=O)=O)C([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C(Cl)C([H])=C2C([H])=C1[H]
[H]N([C@]1([H])C([H])([H])C([H])([H])[C@](C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])OC([H])([H])[H]
[H]N([H])C(=O)C1=C(N([H])[H])C2=C(N=C(N=C2S1)N([H])C([H])([H])C([H])([H])N([H])[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)OC([H])([H])[H])C1=NC2=C([H])C(=C([H])C([H])=C2N1[H])C(=O)C1=C([H])C(=C([H])S1)C([H])([H])C#N
[H]C1=NC2=C(C([H])=C1[H])C([H])=C([H])C([H])=C2S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)OC([H])([H])C3=C([H])C([H])=C([H])C(=C23)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@@]2([H])SC(Br)=C([H])[C@@]2([H])C1([H])[H]
[H]C1=C2C(=C(S1)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])[C@]([H])(OC([H])([H])[H])O[C@]21C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C(N([H])[C@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])N=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])F)C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(OC1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])[C@]1(N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])\N=C(/S[H])N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C1=C2C(N([H])C([H])=C2C([H])([H])[H])=C(N=C1[H])N([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C(C2=C(C([H])=C([H])C([H])=C2[H])C(=O)N1C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C2=NOC3=C([H])N=C(N([H])[C@]([H])(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[H])C([H])=C23)C1([H])[H]
[H]N([H])C1=C2C([H])=NN=C2N(C([H])([H])N1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NC([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])N(N=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC(=O)C(\SC1=NN([H])C(=N1)C([H])([H])[H])=C(/[H])C1=C([H])C([H])=C(O1)C1=C([H])C(Cl)=C(C([H])=C1[H])C(=O)O[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)N([H])[C@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(Br)C([H])=C1OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])C1=O)C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N(C(=O)[C@]([H])(N1C(=O)[C@@]([H])(N2C(=O)OC([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N([H])C1=NC(C2=C([H])C([H])=C([H])O2)=C2N=NN(C2=N1)C([H])([H])C1=C([H])C2=C(N([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C1=C(C(=O)OC([H])([H])[H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C1=C(C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C2([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])O[C@@]2([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C3=C([H])C(C#N)=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)[C@]1([H])[C@@]([H])(O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(Cl)=C1[H])C([H])([H])N([H])C1=C([H])C(=C([H])C(=N1)C([H])([H])C([H])([H])C1=NC(=C(S1)C([H])([H])C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])S(=O)(=O)C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@@]1(C(=O)OC([H])([H])C2=C1C([H])=C1N(C2=O)C([H])([H])C2=C(C3=C([H])C4=C(OC([H])([H])C([H])([H])O4)C([H])=C3N=C12)C([H])([H])[N+]1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(N=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(\N=C(/[H])C1=C(C([H])=NN1C1=C(F)C([H])=C(F)C([H])=C1[H])C(=O)OC([H])([H])[H])C(=S)N([H])C([H])([H])[H]
[H]N(\N=C1/C(=O)N([H])C2=C1C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N1C2=C(SC3=C2N=C(OC([H])([H])[H])C([H])=C3[H])C(=O)N(C1=O)C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H])[C@@]([H])(C(=O)N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])N(N=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C1=NC2=C(S1)C([H])=C([H])C(N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C(F)(F)F)N=C1[H])=C2[H]
[H]N1C(=O)C2=C(C1=O)C1=C([H])N(C3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C1=C(N=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])=C2C2=C1C([H])=C([H])C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@](C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C1([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C(F)(F)F
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=C2C([H])([H])[H])C([H])([H])N1C([H])=NC([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC2=C(S1)N=C([H])N=C2N([H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F)C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC1=NC2=C(N1[H])C([H])=C(Cl)C([H])=C2OC([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N2C(SC3=C2C([H])=C([H])C(=C3[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=N1)C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(=O)N2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]2([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])OC([H])=C1[H])C([H])([H])C#CC1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N([H])C([H])([H])[H]
[H]N([H])C(=NC(=O)C1=C(N([H])C(=N1)C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])[H])N([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(OC(=O)C3=NC([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1=NC([H])=C(C([H])=N1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])[C@]1([H])N=C2N(C([H])=C([H])C(=C2C(=O)N1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C2C([H])=C([H])OC2=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])N(C(=O)C2=C(N=C(S2)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C1([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C(=NN2C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2F)C(F)(F)F)C([H])=C1[H]
[H]N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])OC(=O)N([H])[C@](C(=O)N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]ON([H])C(=O)C1=C([H])SC([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N(C(=O)C([H])([H])N([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H]
[H]C1=NC(=C([H])C([H])=C1Cl)C1=NN=C(N1C([H])([H])C([H])([H])C(F)(F)F)C([H])([H])N1C(=O)C([H])([H])OC2=C(C([H])=C(Cl)C([H])=C12)[N+]([O-])=O
[H]OC1=C([H])C2=C(C(=O)C(=C(C2=O)C2=C(C(=O)C3=C(C(=O)N([H])C([H])([H])C([H])([H])C4=C([H])C([H])=C(C([H])=C4[H])C([H])([H])C([H])([H])[H])C(O[H])=C(O[H])C([H])=C3C2=O)C([H])([H])[H])C([H])([H])[H])C(C(=O)N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])=C1O[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C([H])([H])N1C(=O)C(=O)C2=C(Cl)C([H])=C([H])C(Cl)=C12
[H]C([H])=C([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])[C@]([H])(C(=O)N1C(=O)N(C([H])([H])[H])C([H])([H])[C@@]1([H])C(=O)O[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(N([H])S(=O)(=O)C4=C([H])C([H])=C([H])C(OC(F)(F)F)=C4[H])C([H])([H])C([H])([H])[C@@]3([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])S(=O)(=O)C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)OC([H])([H])C([H])([H])N2[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C(=C([H])C(=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])C1=C([H])C(=C([H])N(C1=O)C([H])([H])C(F)(F)F)C1=C([H])C([H])=NN1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C(Cl)C(=N1)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])N12)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C(=O)N(C(=N2)C([H])([H])OC2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])[H])C([H])([H])C1([H])[H]
COC1=CC2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=C(OC)C=CC(=N3)N3[C@H](CO)CCC3=O)C2=O)C=C1
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C1=C(C([H])=C([H])C(=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(O1)C1=C([H])C(F)=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]SC(=N[H])N1N=C(C2=C([H])C([H])=C([H])C(Cl)=C2[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]OP(=O)(O[H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])[C@]1([H])C(=O)N2N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C(=O)N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(SC2=C([H])C([H])=C([H])N3N=C(N=C23)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C2O[C@@]3([H])C(=O)C([H])([H])C([H])([H])[C@@]4(OC([H])([H])C5=C(Cl)C([H])=C([H])C([H])=C5Cl)[C@]5([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N1C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])[C@]3(O[C@@]([H])(C4=C3C([H])=C(Cl)C(=C4[H])C([H])([H])[H])C(C#N)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C2=C(F)C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[C@]([H])(N([H])[H])C([H])([H])S[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])N(C2=O)C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
OC1=C(SC2=CC=CC=N2)C=C(NS(=O)(=O)C2=CC=CS2)C2=CC=CC=C12
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(Cl)C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])C3([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=N2)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C(\[H])=C(\[H])[C@@]([H])(C#CC2=C([H])C([H])=C(S2)C([H])([H])[H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]N(C1=NC(=C([H])S1)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)N(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])=C([H])C2=C(N([H])C(=O)C([H])([H])C3=C([H])C([H])=C(C(F)=C3[H])C(F)(F)F)C(Cl)=C([H])C([H])=C2C1=O
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])N1C([H])=C(C(=O)N([H])C1=O)[N+]([O-])=O
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C2=NN=C(S2)C2=C([H])C(Cl)=C(OC([H])(C([H])([H])[H])C([H])([H])[H])N=C2[H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])C2([H])[H]
[H]N(C1=NC([H])=NC2=C1N([H])C([H])=C2[H])C1=C([H])C(Cl)=C(OC2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])=C1[H]
[H]N1N=C(N(\N=C(/[H])C2=C([H])C(=C([H])C([H])=C2[H])[N+]([O-])=O)C1=S)C1=NN([H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1SC([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]OC1=C([H])C(I)=C(C([H])=C1OC([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])[C@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])[H]
[H]C1=C(N=C2SC3=C(N12)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])N(N=C2C1=C([H])C([H])=C(O[H])C([H])=C1O[H])C([H])([H])[H]
[H]C1=NC(=C(O1)C1=C([H])N2C(=NN=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])SC([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])[C@@]([H])(N(C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C1(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)S(=O)(=O)C(F)(F)F
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C([H])C(=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C2C([H])=C(N([H])C2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=N/C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)OC([H])([H])[H])\N([H])[N+]([O-])=O
[H]O[C@]1([H])[C@]2([H])C([H])([H])[C@]2([H])[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2([H])C([H])([H])C2([H])[H])[C@]1([H])O[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2(N([H])S(=O)(=O)C3=C(Cl)C(=C(Cl)C([H])=C3[H])C([H])([H])OC3=C4N=C(C([H])=C(C4=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C(F)=C([H])C(F)=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=NN([H])C2=C([H])C(=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(O[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2O1
[H]N1N([H])\C(C([H])=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])=C1/C([H])=C([H])C([H])=C([H])C1=O
C(CC[N]1=CC2=C(C=C1)C1=CC=CC=C1N2)CC[N]1=CC2=C(C=C1)C1=CC=CC=C1N2
[H]N(C(=O)C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C(OC2=C(C#N)C3=C(N=C(S3)C([H])([H])C(=O)C([H])([H])[H])C([H])=C2[H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])N1[H]
[H]ON(C(=O)N([H])[H])C(C#CC1=C([H])C([H])=C(OC2=C([H])C([H])=C(F)C([H])=C2[H])O1)(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2F)C2=C([H])C([H])=C([H])C([H])=C2N([H])C1=O
[H]N(C1=C([H])C([H])=C2N([H])C([H])=C([H])C2=C1C([H])([H])[H])C1=C(C#N)C([H])=NC([H])=C1\C([H])=C(/[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N1N=NN=C1[C@]([H])(N([H])C(=O)C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(Cl)C([H])=C(C#CC([H])([H])OC2=NSN=C2[C@]23C([H])([H])[C@]4([H])C([H])([H])[C@@]2([H])[C@@]3([H])C4([H])[H])C([H])=C1Cl
[H]N(C(=O)C([H])([H])SC1=NC2=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=NN=C(S1)C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])[C@@]([H])(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N1C(=O)C(C2=C(F)C(=C([H])C([H])=C12)C1=C([H])C([H])=C(C#N)N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
CC(C)N1CCC(CC1)OC1=CC=C2N3CCCN(CC4CC4)C(=O)C3=CC2=C1
[H]OC(=O)C1=C(O[H])C(=NC2=C([H])C([H])=C(F)C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1(C2=C([H])C([H])=C([H])C3=C2N(C([H])([H])C2=C([H])C([H])=C(N=C2N3[H])C(F)(F)F)S(=O)(=O)C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=NC(=C([H])C([H])=C2C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C3C(=C([H])C([H])=C2C([H])([H])[H])N(C(=O)C([H])([H])C3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC(=NC(=N1)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C2S[C@]([H])(C([H])([H])[H])C([H])([H])C3=C2C(=C([H])C([H])=C3OC([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=N2)N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(=C([H])S1)[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(C(=C2N=C(SC2=C1C([H])([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N1C(=O)S[C@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C(=C([H])C([H])=N2)C([H])([H])[H])C([H])=C1[H]
[H]C1=C2C(=NO1)C([H])([H])C([H])([H])N(C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C(=O)N(C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N2C(=S)S\C(=C(\[H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C2=O)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(N2C([H])=NC(=C2C2=C([H])C([H])=NC(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])=N2)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1N=C2N=C([H])N=C(C#CC3=C([H])N=C(C([H])=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C2=C1C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]OC1=C(Br)C([H])=C(\C([H])=C2/C(=O)N([H])C3=C([H])C([H])=C(C([H])=C23)C(=O)OC([H])([H])[H])C([H])=C1Br
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(N([H])C(=O)[C@@]([H])(S[H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C2=C([H])C(OC3=C([H])C([H])=NC4=C3C([H])([H])C([H])([H])C(=O)N4[H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C(=O)OC([H])([H])[H])C(Cl)=C1C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C(F)C([H])=C(F)C([H])=C1F)C([H])([H])OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
Cc1ccc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2ccccc2)c(C)c1
[H]O[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@]([H])(N([H])C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(=O)N([H])C1([H])C([H])([H])C1([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]N(C1=C([H])C(=C([H])C([H])=N1)C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C(=O)OC([H])([H])[H]
[H]N(C1=NC([H])=C(Cl)C([H])=N1)S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=O)N(C1=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C(OC([H])([H])[H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C1=NN2C(=N1)N(C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C(=C([N+]#[C-])C2([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
CC1=C(N2C=CN=CC2=N1)C1=NC(NCC2=CC=C(C=C2)C(=O)NC2=CC=CC=C2N)=NC=C1
[H]N(C(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([C@@]([H])(C1=NC2=C(N1[H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C(=O)N([H])S1(=O)=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]N([H])C1=NC2=C(S1)C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C21
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(N=N1)C([H])([H])C([H])([H])C([H])([H])C#N
[H]N(C(=O)C1=C([H])C(N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3N=C2[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])ON([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=NC2=C([H])C3=C([H])C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])O[H])=C([H])C([H])=C3N([H])C2=N1
[H]N(C(=O)[C@]1([H])C2=C(C([H])=C1C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N2C([H])=C([H])N=C2C(=N1)N([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N([H])[C@]1([H])C(=O)N([H])C(=O)[C@](OC2=C([H])C([H])=C(OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])(C1=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])S1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])N(N=C1C1=C([H])C([H])=C(C#CC2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(N(C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])N(C2=C([H])C(SC3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C2C(=NC([H])=N1)N([H])C(=O)\C2=C(\[H])C1=C([H])C(=C(N1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])[C@]1([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C([H])([H])SC2=NC3=C(N2[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])[C@@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N(C1=O)C([H])([H])C(=O)N([H])C([H])([H])C(\[H])=C(/[H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
CC(C)C1=C(CC2=CC=C(CCC(N)=O)C=C2)C(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)=NN1
[H]N(N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@]([H])(OC([H])([H])[C@@]2([H])O[C@@]([H])(OC3=C([H])C([H])=C4C(OC(=O)C([H])=C4C([H])([H])[H])=C3[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]2([H])O[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@@]1([H])O[H]
[H]N(C(=[N+]([H])[H])N1N=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[N+]([H])([H])[H]
[H]C1=NC(=NC([H])=C1N1C(=O)C(Br)=C(OC([H])([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C2=C(C(=O)N([H])C2=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1Cl
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1C(=O)N([H])[C@@]([H])(C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C(Cl)C([H])=C1N([H])C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)C1=O)[N+]([O-])=O
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=NC(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OP(=O)(O[H])C(N([H])[H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])P(=O)(O[H])O[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2OC([H])([H])C([H])([H])[H])C([H])([H])C2=NC([H])=C(S2)C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C(F)=C([H])C(=C1[H])C1=C(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])OC1=O
[H]O[C@]([H])(C([H])([H])OC1=C2C(N([H])C3=C2C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C1[H])C([H])([H])N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C(C([H])=C(C(C#N)=C1[H])C(F)(F)F)N1C(=O)N2[C@]([H])(C1=O)[C@@]1([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=N[C@]([H])(C2=NC(=C(N2C2=C([H])C([H])=C(Cl)C([H])=C12)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H]
[H]N(C1=C2N=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C3=NC([H])=C(F)C([H])=N3)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=O)C(=O)C2=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])S[H])[C@]([H])(OC(=O)C1=C([H])SC(=N1)[C@@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H])C([H])([H])S[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C2=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=NC(=C([H])S1)C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC2=C3C([H])=C([H])N(C3=NC([H])=N2)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C2=C(O1)C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1=C(C([H])=C2C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC2=NN=C(C2=C1C#CC1=C([H])N=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N(C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]N(C(=O)N([H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC(=C([H])S1)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C(F)(F)F
[H]O\C(OC([H])([H])C([H])([H])[H])=C1\C(=NC(=C(C(=O)OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=NC([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]OC(=O)C1=C(OC2=C(Cl)C([H])=C([H])C([H])=C2N([H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(N([H])C2=C([H])C3=C(N=C([H])N3[H])C([H])=C2[H])=C([H])C([H])=N1)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C(=N/C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C([H])([H])N([H])[H])\N([H])[N+]([O-])=O
[H]N(\C(=N/C#N)N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C2=C1N([H])C([H])=C2C([H])([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(=O)[C@]([H])(N([H])C(=O)C1=C(Cl)C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])[H])C1=NN([H])C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])(N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C2([H])[H]
[H]N1C(=NC2=C(N3C([H])([H])C([H])([H])N(C([H])([H])C4=NOC(=C4[H])C([H])([H])[H])C([H])([H])C3([H])[H])C(Br)=C([H])N=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C(N([H])[H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\C(=N\C#N)N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(OC(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=NC4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C([H])=C2C(S\C(=N/N(C(=O)C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[H])C2=O)=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C2([H])[H]
[H]N1C([H])=C([H])C2=C(C([H])=C([H])C([H])=C12)C([H])([H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C11C([H])([H])C([H])([H])N(C2=NC3=C(O2)C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC(=O)[C@@]([H])(N([H])[H])C1=C(N(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NN([H])C(=C2[H])C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C(=NC([H])=C1[N+]([O-])=O)C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C(N1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])N(C2=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])=N2)C1=C(C#N)C([H])=NC([H])=C1\C([H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(\C([H])=C2/SC(=O)N(C2=O)C([H])([H])C(=O)O[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C4N(C(=O)C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C4=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@@]([H])(N([H])C(=O)C1=NC(=C([H])N=C1N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N([H])N=C1[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]SC1=NN=C(S1)N([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C(F)=C(F)C(F)=C1F
[H]N([H])C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C(Cl)=C1[H])N1N=C([H])C2=C([H])N=C(N([H])[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C12
[H]OC(=O)[C@@]1([H])O[C@]2(O[C@](C(=O)O[H])(C([H])([H])OC2=O)[C@]1(O[H])C(=O)O[H])C([H])([H])C([H])([H])C(=C([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(=C([H])C([H])=C2N1[H])C(=N[H])N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(O1)C(\[H])=C1\C(=O)N([H])C2=C([H])C([H])=C(F)C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]S\C(=N\C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(O1)C([H])=C(C([H])=C2[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]
OC1=CC=CNC1=S
[H]N([H])C(=O)C1=C([H])N(C2=C(C([H])=NC(=N2)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C1=O)C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C1=C(O[H])C([H])=C2C3=C(C([H])=C([H])C2=C1[H])C1=C(N3[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=NC(Br)=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C(S1)N(C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@]1([H])C([H])([H])O[C@@]([H])(O[C@]1([H])C1=C(O[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H])\C1=C([H])N=C([H])C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])N([C@]([H])(C4=C([H])C([H])=C(C([H])=C4[H])C([H])([H])C4=C([H])C5=C(OC([H])([H])O5)C([H])=C4[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C3([H])[H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]O[C@](C(=O)OC([H])([H])C#CC([H])([H])N1C([H])([H])[C@]2([H])C([H])([H])[C@]2([H])C1([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)C1=C(ON=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]C1=C([H])C([H])=C(N2C(=O)C(Cl)=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C2=O)C(Cl)=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])OC(=O)[C@@]([H])(N([H])[H])C1=C(N(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(N([H])C(=O)C2=C(F)C([H])=C(C([H])=C2[H])C(=N[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
CC1=CC=C(C=C1C)C1=NN(C(C1)C1=CC=C(C=C1)N(O)=O)C(N)=S
[H]C1=C(SC2=C1C(=NC([H])([H])C1=NN=C(N21)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C#CC([H])([H])N1C(=O)C([H])([H])OC2=C1C([H])=C([H])C(F)=C2[H]
[H]N(C(=O)[C@]1([H])C(=O)N2C3=C(C([H])=C([H])C([H])=C13)C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H])C1=NC([H])=C([H])S1
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2C(=O)C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(S[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])OC([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C2=C([H])C([H])=C([H])C(\C([H])=C(/[H])C3=NC4=C(C([H])=C([H])C(Cl)=C4[H])C([H])=C3[H])=C2C([H])=C1[H]
[H]N1C(=C2C(=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@]([H])(C([H])([H])C([H])([H])N2C(=C(C(C(=O)OC([H])([H])C([H])([H])[H])=C2C([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])([H])O2)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=N2)C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])N1[H])C(=N[H])N([H])[H]
[H]C#CC1=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C([H])C(=C1[H])C([H])([H])N([H])C(=S)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(S1)N=C(N=C2N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]C1=C([H])C([H])=C(C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]N1C2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(OC(=O)C1=C([H])C3=C(C([H])=C([H])C([H])=C3[H])N1C([H])([H])[H])C2([H])[H]
[H]N(C(=O)O[C@]1([H])C(=O)N(C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1N(C2=O)C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C2([H])[H])[C@](O[H])(C2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[C@@]1([H])N([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])N=C([H])N1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])S[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]ON([H])C(=O)[C@@](C([H])([H])[H])(C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])[C@]([H])(O[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2F)C([H])([H])C2=NC([H])=C(S2)C2=C([H])C([H])=C([H])S2)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NOC(=N2)[C@@]([H])(N([H])C(=O)OC([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C1=NC(=C([H])N2C([H])=C(N=C12)C(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])SC2=C1C([H])=C([H])C([H])=C2[H]
[H]OC1=C(O[H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C2=C3C(=NC4=C2C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N1C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])=C([H])C2=C([H])C([H])=C(N([H])C([H])([H])[H])C([H])=C12
[H]N(C1=C(C#N)C(=O)N([H])S1)C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]N1C2=C([H])C(C#CC3=C(F)C([H])=C(F)C([H])=C3[H])=C([H])C([H])=C2N=C(C2=C([H])C([H])=C([H])C(C#N)=C2[H])C([H])([H])C1=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C([H])=C(Br)C([H])=C(C2=N1)C([H])([H])[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(C([H])=C(N([H])C([H])([H])C2=C([H])N(C([H])=N2)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])[C@]([H])(N1C([H])=NC([H])=C1[H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C(=S)N=C([H])N2[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C(C#N)C([H])=C1[H])C([H])([H])N1C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@](=O)(O[H])O[P@](=O)(O[H])OP(=O)(O[H])O[H])[C@@]1([H])O[H])N1C([H])=C([H])C(=O)N(C1=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(N([H])[H])=C1[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])\N=C(/[H])C1=C([H])N([H])C2=C([H])C([H])=C(Br)C([H])=C12
[H]C1=C([H])C2=C(C([H])=C([H])C(=N2)N2C([H])([H])C([H])([H])N(C([H])([H])[C@]3([H])OC4=C5C([H])=C([H])C(=NC5=C([H])C([H])=C4OC3([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1Br
[H]N([H])C1=C2N=C(N=C2N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H])C(OC([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C([H])C(=C1C1=C2N=C(C([H])=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])C([H])([H])C3([H])[H])N2N=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)N1C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])N([H])[C@]1([H])C([H])([H])C2([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(C2=C([H])C3=C([H])C(=C([H])C([H])=C3N2[H])C(=N[H])N([H])[H])=C(O[H])C(=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]N(C(=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C2C(=C1[H])[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C([H])=C2N=C(SC2=C1[H])[C@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=NC2=C([H])C(=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C2C(N([H])C([H])=C2S(=O)(=O)C2=NN=NN2C([H])([H])[H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C2C(=NN([H])C2=N1)N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2C(=C1[H])[C@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C3SC([H])([H])C([H])([H])C3=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC1=NC2=C(C([H])=C3C(N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@]3([H])C([H])([H])[H])=C2[H])C(=C1[H])C(F)(F)F
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])[C@]2([H])C([H])([H])N(C(=O)C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C1([H])[H]
CN1C2=C(C=CC=C2)C2=C1C=CC(\C=C\C(=O)C1=CC=CC(NC(=O)C3=CC(=CC=C3)C(F)(F)F)=C1)=C2
[H]O[C@]([H])(C([H])([H])OC1=C2C([H])=C(N([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C3=C(S2)C([H])=C([H])C(Cl)=C3[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]OC(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C2=C1N([H])C1=C([H])C([H])=C([H])C([H])=C1O2
[H]N(C(=O)C1=C([H])C([H])=C(Br)O1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C#CC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])=C1[H]
[H]C1=C2OC([H])([H])C([H])([H])OC2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=C2/C(=O)N([H])C3=C([H])C([H])=C(Cl)C([H])=C23)\C([H])([H])[H])C([H])=C1[H]
[H]OC1=C2C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C2=NC2=C1C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C2[H]
[H]C1=C([H])C(=C([H])C2=C1OC([H])([H])O2)C1=NOC(=N1)[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NN=C(O1)C1=C([H])C([H])=C(OC([H])([H])C2=NOC(=N2)C2=C([H])C([H])=C(S2)C(=O)C(F)(F)F)C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C([H])C([H])=C(I)C([H])=C2O1
[H]C1=C([H])C(Cl)=C(Cl)C([H])=C1N(C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])[P@](=O)(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])SC1(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])=C1[H]
[H]N=C1C([H])=C([H])N(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1C1=C(C([H])=C(\C([H])=C(\[H])C(=C([H])[H])C([H])([H])[H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C(=O)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])N1C([H])=C(N([H])C1=S)C1=C([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2OC1=O
[H]N(C(=O)C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=NC2=C(C([H])=NN12)C(=O)OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])P(=O)(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
OB(O)C1=CC2=CC=CC=C2O1
[H]N(C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C12
[H]O[C@@]1([H])[C@@]([H])(N([H])C(=O)C([H])([H])N2C(=O)[C@@]([H])(N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=N[H])N([H])[H]
CCC1=C(CCCC(O)=O)C=NC=C1C1=NSC(=N1)C1=CC=C(OC(C)C)C(Cl)=C1
[H]C1=C([H])N2C(=NC(=C2C2=C([H])C(OC3=C([H])C(=C([H])C([H])=C3[H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C(=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]\C(I)=C(/[H])C([H])([H])OC(=O)[C@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])N1C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N1C(=O)[C@@]([H])(N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])S[C@@]([H])(C2=C([H])SC([H])=C2[H])C1([H])[H]
[H]OC(=O)C1=C([H])C2=C(SC(=C2[H])[C@@]([H])(N2C([H])=NC([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])O[H])C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])N([H])[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)N([H])[H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C2=C(C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C2=C(N=C(C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C2C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C([H])(F)F)C([H])([H])C([H])(F)F
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2OC1=N[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=NC(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(SC2=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(=C2C(F)(F)F)C(F)(F)F)=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N1C(=O)N(C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(N([H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C2[H])N(C2=C([H])C3=C(C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=NC2=C(O[H])C([H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])C([H])=C([H])C(F)=C1F
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=[N+]([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C(=O)C1=C([H])N(N=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=N[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C2=C(F)C([H])=C([H])C([H])=C12
[H]N(OC([H])([H])[H])C(=O)C1=C([H])C([H])=C(C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)N([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=N4)C(=C23)C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C(C#N)=C([H])C([H])=C1[H])C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C([H])C([H])=N1)C1=NC([H])=C([H])S1
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(N([H])SC(=S)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])[C@]([H])(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C1(C2=NN=C3N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=NC(=NC(=C1[H])C([H])([H])[H])N(C1=C(Br)C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[N+]([O-])=O
[H]ON([H])C(=O)[C@]([H])(N1C(=O)[C@](N([H])[H])(C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C(=NC4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]12C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C5=C(N(N=C5[H])C(=O)C5=C([H])C([H])=NC([H])=C5[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C(=O)C1=C([H])N=C(N=C1N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])N([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C(F)C([H])=C2[H]
[H]N1C([H])=C([H])C2=C([H])C([H])=C(C([H])=C12)C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])O1)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1OC1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C(=O)N([H])C([H])([H])C1=C([H])N([H])C(=C1[H])C(=C1/C(=O)N([H])C2=C([H])C([H])=C(N([H])C(=O)N([H])[H])C([H])=C12)\C([H])([H])[H]
[H]N([H])C(=O)C(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C(Br)C([H])=NC(=N1)N([H])C1=C([H])C(N([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(O[C@]([H])(C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])[H])C(=C(OC2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])N=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(ON=C1C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C(N2C(=C1[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C2([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])O[C@]([H])(O[P@](=O)(O[H])O[P@](=O)(O[H])O[P@](=O)(O[H])O[P@](=O)(O[H])OC([H])([H])[C@@]2([H])O[C@@]([H])(N3C([H])=C([H])C(=O)N([H])C3=O)[C@]([H])(O[H])[C@]2([H])O[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]O[C@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])[C@]4([H])C(=C([H])C([H])([H])[C@]5([H])N=C(OC([H])([H])[C@@]45C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]3([H])C(=O)C([H])([H])[C@]2(C([H])([H])[H])[C@@]1([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(F)=C([H])C(=C1[H])C1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)C2([H])[H]
[H]OC1=C(C(Cl)=C([H])C([H])=C1N([H])C(=N\C#N)\N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
CN(CC(=O)N1CCC[C@H]1B(O)O)C(=O)C1CCC(=O)N1
[H]C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C([H])([H])N1C([H])([H])C([H])([H])C(=O)[C@]([H])(C1([H])[H])C([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C(S1)N=C([H])N=C2N([H])C1=C([H])C([H])=C(C(Cl)=C1[H])C(F)(F)F)C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N=C(N([H])[H])N([H])\N=C(\C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=N\N([H])C(=N[H])N([H])[H])\C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C(Cl)C([H])=C(C(=C1[H])C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N1[C@@]2([H])C(C(=O)N(C([H])([H])C3=C(Cl)C(Cl)=C([H])C([H])=C3[H])C3([H])C([H])([H])C3([H])[H])=C(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])OC4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])[C@]1([H])C([H])([H])N(C(=O)C([H])([H])[H])C2([H])[H]
[H]C1=C2C(=C([H])C([H])([H])C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])[C@]33OC(=O)C([H])([H])C3([H])[H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]OC(=O)C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=N[H])N([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C([H])([H])C2=C([H])C(=C([H])C([H])=C2C([H])([H])C1([H])[H])[C@@]([H])(N1C([H])([H])[C@]([H])(N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=NN1C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NN=C(SC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC2=C([H])C(Cl)=C(C([H])=C2N2C([H])=NC([H])=C12)N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C(F)=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])[C@]([H])(O[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C(N([H])C2=C([H])C(=NC(=N2)N2C([H])=NC3=C2C([H])=C([H])C([H])=C3[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C(=C1[H])N1C(=O)C2=C(C3=C(N=C([H])N=C13)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H])C1=NC(=NC2=C1N(N=C2C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C(F)(F)F)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C1=C([H])C([H])=C([H])C(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])N=C(C([H])=C1[H])C([H])([H])N(C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])N(C(=O)N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])[C@@]([H])([O-])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[C@@]1([H])SC(=O)N([H])C1=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C1=C2N=C(N(C2=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H])C([H])(C1([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=NC(=NC2=C1N=C(C([H])([H])C1=C([H])C([H])=C([H])S1)C2([H])[H])N([H])[H]