[H]OC1(C(=O)N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C2=NS(=O)(=O)C3=C([H])C(F)=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]O\C(=C(\C#N)C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1([H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2[C@]2(O[C@]1([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=C(C([H])=C(S1)C#N)C([H])([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(O2)C([H])([H])C2=C([H])C3=C(C([H])=C2C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1(OC2([H])[H])C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C(=O)C1=C([H])C2=C(C#N)C([H])=C([H])C([H])=C2S1
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[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1F)[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NSC4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])N([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[C@@]([H])(N([H])[C@]2([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C(=O)S[C@]([H])(C1=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC2=C(C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C(F)=C1[H]
[H]OC(=O)C([H])([H])OC1=C(Cl)C([H])=C(\C([H])=C2/SC3=NC(=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(N3C2=O)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1Cl
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])C([H])([H])[H])C([H])([H])N([H])[C@]([H])(C([H])([H])N([H])[C@]([H])(C([H])([H])N([H])[C@]([H])(C([H])([H])N([H])[C@]([H])(C([H])([H])N([H])[C@]([H])(C([H])([H])N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]O[C@@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1N(C(=O)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]C1=C(SC([H])([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])N(N=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=NC(=NC(N3C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])S(=O)(=O)C([H])([H])[H])=C12)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
ONC(=O)C1=CC=C(C=C1)C(=O)NC1=CC=CC=C1
[H]N([H])C1=NOC2=C1C(=C([H])C([H])=C2[H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N([H])C(C(=O)N([H])[C@@]([H])(C1=NN=C(N1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(O[H])C([H])([H])N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C(C(=O)N([H])C1=O)C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N(C1=C([H])C(F)=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2[H])N2C(=O)N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])OC2=C1C([H])=C(C([H])=C2[H])C1=NN2C([H])=NN=C2S[C@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=O)C2=C([H])C(Br)=C([H])C([H])=C2O1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
[H][C@@]12CC[C@@]3(C)[C@@H](C[C@@H](I)C(=O)[C@]3([H])[C@@]1(C)C[C@H](OC2=O)C1=COC=C1)C(=O)OC
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1[H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C#N)C([H])=C1C(=O)C([H])([H])[H]
[H]C1=C(Br)OC(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=NN(N=N1)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]C1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(N1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1OC([H])([H])[H])C1=NN(\C(S1)=N\C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]1([H])N([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(Cl)=C(C([H])=C([H])C2=N1)C([H])([H])N([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1(N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(C([H])=C(C([H])=C2[H])C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C(Cl)C([H])=C(C([H])=N1)C(F)(F)F)C([H])([H])C([H])([H])N1C(=O)C([H])=C([H])C1=O
[H]OC(=O)C1=C(C2=C(N(C1=O)C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C1=C(O2)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C([H])([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(OC(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]2(C([H])([H])OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]([H])(OC(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]3([H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]12OC3(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])[C@]1(OC(=O)N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C(=NC([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C(C([H])=C([H])C(OC([H])([H])[H])=C1[H])S2(=O)=O
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N(C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=C1[H])C(F)(F)F)C([H])([H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=N[H])N([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C(OC(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
CC1=NC2=CC=C(C=C2N2C1=NN=C2C1=CC=CC=C1Cl)C(=O)NCCN1CCOCC1
[H]N(C(=O)C1=C(C2=C([H])C([H])=C([H])C([H])=C2S1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=NC([H])=C([H])C([H])=C12
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C(=O)N([H])\N=C(/[H])C1=C([H])C(OC([H])([H])[H])=C(OC(=O)C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@@]([H])(S[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=NC(=C(O1)C1=C([H])N2C(=NN=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=C(Cl)C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C(F)C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\[H])C3=C(C4=C(N3[H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C2=C1[H]
[H]N(C#N)C(=N\C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])\N1C([H])([H])C([H])([H])C(=C2C3=C(C([H])=C(Br)C([H])=N3)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])[C@@]([H])(O[H])C([H])([H])N2[H])=C([H])N=C1[H])C1=C([H])C(Br)=C([H])C(Br)=C1O[H]
[H]N(C(=O)C([H])([H])SC1=NN=C(N1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1[C@@]2([H])C(C(=O)N(C([H])([H])[H])C([H])([H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])=C(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C4=C(OC([H])([H])[H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])[H])C2([H])[H]
[H]OC(=O)C([H])([H])N1C([H])=C([H])C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC3=C([H])C4=C([H])C([H])=C(C([H])=C4C([H])=C3[H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C12
[H]O[C@]1(N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])N([H])C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC(=NC2=C1N=NN2C1=C([H])C([H])=C(C([H])=C1Br)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)[C@@]([H])(C([H])([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=N[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CN1C(=O)C(=CC2=CN=NC(C3=C(Cl)C=CC=C3)=C12)C1=CC(=NC=C1C)C(=O)NC1CC1
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C(=N3)C([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]N(C(=O)OC([H])([H])C1=NC([H])=C([H])S1)[C@]([H])(C([H])([H])N(C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])N=C([H])S1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C2C([H])=C([H])C(=O)N(C2=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(SC([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])SC(=N[H])N([H])[H])N([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N1N=C(N=C1C1=C([H])C([H])=C(F)C([H])=C1[H])[C@@]12C([H])([H])C([H])([H])[C@@](C3=NN=C(N3C([H])([H])[H])C3=C(C([H])=C([H])C([H])=C3[H])C(F)(F)F)(C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
O=C1C2CCN(CC2)\C1=C/C1=CN(CC2=CC=C(C=C2)C#N)C2=CC=CC=C12
[H]N1C([H])=NC([H])=C1C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(C#N)=C([H])C([H])=C2N([H])C1=O
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C(=C([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])[C@@]1([H])N=C(C2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C(C(=NC3=NC([H])=NN23)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])C2=NC(C#N)=C(O2)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1Cl
[H]O\N=C(/[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N([H])C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]\C(C1=C([H])C([H])=C(Br)O1)=C1\C([H])=C(OC1=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N3C(=O)C([H])([H])C([H])(C4=C([H])C([H])=C(Cl)C([H])=C4[H])C([H])([H])C3=O)C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]SC([H])([H])[C@]([H])(N([H])[H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C(N=C(O1)C1=C2C([H])=C([H])C(=NC2=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(Cl)C([H])=C(\C([H])=C2\C(=O)C3=C([H])C([H])=C([H])C(=C3C2=O)[N+]([O-])=O)C([H])=C1Cl
[H]O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C2=C(S1)C(=NC(=N2)N(C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C([H])N1C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C2=C(C([H])=C(C([H])=C2[H])C(=O)C([H])([H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C(N=C1C([H])(C1([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)[C@@]1([H])[C@]2([H])C([H])([H])N(C3=C([H])C([H])=C(C([H])=C3[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[C@]12[H]
[H]\C(=C1/C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(=C([H])C([H])=C2O1)C(=N[H])N([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C(SC(=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
CC1=C(C=CC(O[C@@H](CC2=CC=CC=C2)C(O)=O)=C1)C1=CC=CC=C1
[H]N(C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(Br)=C2C3=C([H])C(O[H])=C(O[H])C([H])=C3N(C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C2=C1O[H]
[H]N(C1=C([H])N=C([H])C(N([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])C([H])=C([H])C(OC2=C([H])C(Cl)=C(Cl)C([H])=C2[H])=C1[H]
[H]OC(=O)C(\[H])=C(\C1=C([H])C2=C(O1)C(=C([H])C([H])=C2[H])C1=C([H])C(=C([H])C(=C1OC([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])=C(C(=O)N=C1SC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N=C1[H]
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[H]N=C(N([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C(Cl)=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
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[H]N(C(=O)C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H])C1=C2N=NN(C2=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C(=NN=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=N[C@@]([H])(C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C(C(=O)OC([H])([H])[H])=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NN([H])C([H])=C1[H])C1=C(N2N=C([H])C([H])=C([H])C2=N1)C1=NC(=NC(N([H])C2=NN=C([H])C([H])=C2[H])=C1[H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C2C(=N1)C(C1=C(C([H])=C([H])C(Cl)=C1[H])C([H])([H])C2([H])[H])=C1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1N=C([H])C(=C1[H])C1=C([H])C(C2=NC3=C(O2)C([H])=C([H])C([H])=C3[H])=C(N=C1[H])N([H])[H]
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[H]N(C(=O)C([H])([H])N1N=C(C([H])=C1C([H])([H])[H])C1=NC2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N1C([H])=C(\C([H])=C(/[H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C(=O)N2C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C(Br)=C2[H]
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[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl)C1=C(SC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC2=C1C([H])([H])N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C1=C([H])C2=C([H])C(F)=C([H])C([H])=C2N([H])C1=O
[H]OC1=C([H])C(=C(OC([H])([H])C(=O)N([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])C(=O)N2C([H])([H])SC(C([H])([H])[H])(C([H])([H])[H])[C@@]2([H])C(=O)N([H])[C@@]2([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[C@@]2([H])O[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C(\[H])=C(/[H])C1=C2N(C(=O)C(F)(F)C2=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])S(=O)(=O)C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N([H])C1=NC(C2=C([H])N([H])C3=C(Br)C([H])=C([H])C([H])=C23)=C(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N1C2=C([H])C(=C(Cl)C([H])=C2N=C(C2=C([H])C([H])=C([H])C(=C2[H])N2C([H])=NC([H])=C2[H])C([H])([H])C1=O)C(F)(F)F
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=C(C(=O)N([H])[C@]2([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])C3([H])[H])C(=O)C2=C([H])C([H])=C(SC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C12
[H]N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C2=C(OC([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(=C23)C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])S[C@](C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])N=NN=N1)C([H])([H])C([O-])=O)=[N+]([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1F)N1C([H])=C([H])C([H])=C([H])C1=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C(Br)C([H])=C(\C([H])=C(/[H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C(=C2[H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
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[H]OC(=O)C1=C([H])C([H])=C(N([H])C2=NC(=NC(=C2C([H])([H])C([H])=C([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(SC2=C([H])C([H])=C([H])C([H])=C2[H])S1)[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=NC(O[H])=C(N=C1C([H])([H])[H])C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C(C([H])=C(O[H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[H]
[H]C1=C(OC2=C([H])C([H])=NC([H])=C12)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(Cl)C([H])=C2[H]
[H]N(C1=C([H])C([H])=C([H])N=N1)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
COC1=CC=C(C=C1)C1=NN=C(S1)C1=C(O)C=C(O)C=C1
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C1=NC([H])=C([H])C([H])=N1)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C(=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]OC([H])([H])[C@@]([H])(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])SC([H])([H])[C@]2([H])N([H])C(=O)N([H])[C@]12[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])S[C@@]([H])(SC([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(\C([H])=C(/[H])C2=NC3=C([H])C(Cl)=C([H])C([H])=C3C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@]1([H])C2=C([H])C([H])=C(N=C2OC2=C1C([H])=C([H])C([H])=C2[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=NN=C([H])S1
[H]N([C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)N2C([H])=NN=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2C2=NN=C([H])N2[H])C2=C([H])N=C([H])C([H])=C12)C1=C([H])C([H])=C(F)C([H])=C1F
[H]N([H])C(=O)[C@@]1([H])N(C([H])([H])C2=C([H])C(=O)OC3=C([H])C(OC([H])([H])C4=C([H])C(F)=C([H])C([H])=C4[H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C2N(C(=O)N(C2=N1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
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[H]N([H])C1=N[C@](N(C(=N1)N([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN=C(C2=C1C([H])=C1C([H])=C([H])C([H])=C([H])N21)C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
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[H]C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C(F)=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(N=C(C([H])=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)N([H])[C@]([H])(C1=O)C1=C([H])C(Cl)=C([H])C([H])=C1S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]1([H])O[C@@]1([H])C1=C2N=C([H])C(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])=C(N([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[H])C2=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])C1(C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N1C(=O)N(C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N(C([H])([H])[H])[C@@]1([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(OC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(F)=C(F)C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C(F)=C3[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C(Cl)=C([H])N=C(N([H])C([H])([H])C(F)(F)C2=[N+]([O-])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])(F)F
[H]N=C(N([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])OC1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
CC1=NC2=CN(N=C2C(NC(=O)C2=CC=CN=C2)=N1)C1=CC=CC=C1
[H]C([H])=C(C(=O)N([H])C1=C([H])C2=C(N=C([H])N=C2N([H])C2=C([H])C(Br)=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])O[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=S)C([H])([H])[H]
COC1=CC(OC)=C2C(=O)C=C(OC2=C1)C1=CC(OC)=C(OC)C(OC)=C1
[H]N([H])C(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C(=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)C2=C(O[H])C(=C(O[H])C([H])=C2[H])[C@@]2([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@]([H])(C3=C(O[H])C([H])=C(O[H])C([H])=C3[H])[C@@]2([H])C(=O)C2=C([H])C(O[H])=C(C(O[H])=C2[H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C(Br)=C3[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)C2=C(C3=C([H])C([H])=C([H])C([H])=C3S2)C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])=NC3=C([H])C([H])=C(C([H])=C3C2=O)N(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])C1=NN=NN1C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([O-])=O
[H]C1=C(N(N=C1C([H])([H])OC1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C1SN(C2=C1C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
FC(F)(F)OC1=CC=C(NC2=NC=NC(=C2)C2=C3C=CNC3=NC=C2)C=C1
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(F)C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H]
[H]OC(=O)C([H])([H])C1=C(N([H])C2=C([H])C([H])=C(F)C([H])=C12)C(=O)C1=NC([H])=C([H])C(=C1[H])C([H])([H])[H]
COC1=CC2=C(CN(C[C@]3(NC(=O)NC3=O)C#CC3=CC=C4C(CC[C@]44NC(=O)CC4=O)=C3)C2=O)C=C1
[H]S[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])SC([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1=O
[H]OC1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N([H])[C@@]2([H])C([H])([H])C([H])([H])C3=C(C([H])=C([H])C(F)=C3[H])[C@]2([H])C([H])([H])C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])=NC(=C2C2=NC(OC([H])([H])[H])=NC([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2N(C(=C3[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])SC1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N([H])C1=C(C(=NC(=N1)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])[N+]([O-])=O
[H]OC([H])([H])C1=C([H])C([H])=C(O1)C1=C([H])C2=C(N=C([H])N=C2N([H])C([H])([H])C2=C([H])C([H])=C(O2)C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SN=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]SC([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C(Cl)=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C([H])([H])[C@]1([H])OC(=O)[C@@]2([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C3([H])[H])[C@@]12[H]
[H]OC(=O)C1=C([H])C([H])=C(O1)C1=C([H])C2=C(N=C([H])N=C2N([H])C([H])([H])C2=C([H])C([H])=C([H])S2)C([H])=C1[H]
[H]C1=NC2=C(C([H])=C(N=C2C#N)C2=C([H])C(=C(OC([H])([H])C([H])([H])C3([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C(F)(F)F)N1C([H])([H])[H]
[H]C1=C([H])C(C2=C3N=C(C([H])=C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]OC([H])([H])C1=C(N=C(C(=C1C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])OC1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])[S@](=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C(S1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)C(C1=C([H])C([H])=C([H])O1)(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])OC([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(S2)C2=C([H])C([H])=C3C(N=C([H])C(C#N)=C3N([H])C3=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C3Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N1N=C(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1N1C(=O)N2C3=C(C([H])=C(N=C13)C([H])([H])[H])N(C([H])([H])C2([H])[H])[C@@]([H])(OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]N([H])C1=NN([H])C2=C1C(=C([H])C([H])=C2[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N=C([H])N1C([H])([H])[H])N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C2=C(N=NC2([H])[H])C([H])=C1[H]
[H]C1=C(N(C(OC([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=N1)C([H])([H])[H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C(C([H])=C1[H])C1=C2N(C([H])=C([H])N=C2N([H])[H])C(=N1)C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@]([H])(O[C@@]2([H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@@]([H])(O[C@]2([H])C([H])([H])O[H])N([H])C(=S)N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]C1=NC2=C(C([H])=C([H])C(=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C4=C([H])C(OC([H])([H])[H])=C([H])C([H])=C4C([H])([H])C([H])([H])[C@]23[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(\C([H])=C1/[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N1C(=O)C([H])=C(OC(=O)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
CC1=CC=C(OCCCC2=CC=CC(C#CCOC3=CC=C(C)C=C3)=[N+]2C)C=C1
[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])C([H])([H])[H])C([H])([H])N([H])C2=C(OC([H])([H])[H])C([H])=C([H])C(=C2[H])C(F)(F)F)=N1
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])N(C([H])([H])[C@@]([H])(N([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])OC1=C([H])C(F)=C([H])C2=C1OC([H])([H])C([H])([H])C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(OC(=O)C3=C2C([H])=C([H])C2=C3OC([H])([H])O2)C([H])([H])C1([H])[H]
[H]N1N=NN=C1C1=C([H])C(F)=C([H])C(=C1[H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])C1=NC2=C(N=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NC([H])=C(F)C([H])=N3)C([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])SC([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])([H])[S@@](=O)C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C#CC2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])SC1=NN=C(N1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=NC2=C(C([H])=C(C([H])=C2[H])C(F)(F)F)C(C2=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C2[H])=C1C([H])([H])C([H])([H])O[H]
[H]N([H])C1=NC(N([H])[H])=C2C(=N1)C([H])=C([H])C([H])=C2C#CC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N([H])C1=C([H])C([H])=C([H])C2=C1N=C([H])C([H])=C2[H])C(=C1/C([H])=C([H])C([H])=C([H])C1=O)\C([H])([H])[H]
[H]N(C1=NC2=C(S1)C([H])([H])C([H])([H])OC1=C2C([H])=C(F)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(N([H])C(=O)C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N(C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C1=NN=C(O1)C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(O[H])=C([H])C(C3=C([H])C([H])=C([H])O3)=C2O1
[H]C([H])=C([H])C([H])([H])SC1=NC2=C(N=N1)C1=C(C([H])=C([H])C([H])=C1[H])N(C(=O)C([H])([H])[H])[C@@]([H])(O2)C1=C([H])C([H])=C(S1)C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=NC(=NC([H])=C1[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1(O[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Br)S1
[H]N(C(=O)C1=C(N=C(N1C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[S@](=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(Cl)=C([H])C([H])=C1C([H])([H])N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N(C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(F)C(=C([H])C([H])=C1[H])C(F)(F)F)[C@@]([H])(C([H])=O)C([H])([H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(N([H])C2=NC3=C(N=C([H])N3[H])C(=N2)C2=C([H])C([H])=NC([H])=C2[H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=NC([H])=C(C([H])=C2C(=N1)N([H])[H])C([H])([H])OC(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])[C@@]2([H])O[C@]([H])(C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC3=C([H])C(Cl)=C(C([H])=C23)C([H])([H])C2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C2[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])[C@]2(C(=O)N([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C(=O)N(C([H])([H])C(F)(F)F)C([H])([H])[C@]([H])(C2=C(F)C(F)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C(=C([H])C([H])=C2N=C(C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1=O)C([H])([H])[H]
[H]OC([H])([H])C([H])([H])[C@@]1([H])C2=C(C([H])=C(N2[H])C2=C([H])C([H])=NC(=N2)N([H])[H])C(=O)N([H])C1([H])[H]
[H]N(C([H])=O)C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])N1N=C(C([H])=C1N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])OC(=O)C([H])([H])C1=C([H])SC2=C1C([H])=C([H])C([H])=C2[H]
[H]N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])(OC2=C(C([H])=C([H])C([H])=N2)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(N1S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C(=O)N([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C([H])=C1[H]
[H]O[C@@]1(C(=O)OC([H])([H])C2=C1C([H])=C1N(C2=O)C([H])([H])C2=C([H])C3=C(N=C12)C([H])=C([H])C(OC(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])=C3[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1(N([H])C(=O)C([H])([H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C(=O)OC([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(Cl)=C1Cl)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(OC(=O)C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1=NC([H])=C(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N1C(=NC2=C1C(=C([H])C(=C2[H])C(F)(F)F)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]N1C2=C(N=C1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]\C(\C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])=C(\[H])C1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H]
[H]N1C2=NN=C(C3=C([H])C([H])=C([H])O3)C(=O)N2C2=C([H])C([H])=C([H])C([H])=C12
[H]OC1=C([H])C(Br)=C2OC(=NC2=C1[H])C1=C([H])C(=C(O[H])C([H])=C1[H])C(F)(F)F
[H]N(C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(=NN1C1=C([H])C(N([H])C(=O)C([H])([H])[H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C(F)(F)F)C(=O)C1=NOC(=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC(=NN1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
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[H]N(C1=NC2=C(C([H])=N1)C([H])([H])C(=O)N([H])C1=C([H])C([H])=NC([H])=C21)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C3(N([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])=C(C([H])=C1[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
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[H]N1C(=O)C([H])([H])C2=C1C([H])=C1ON=C(C1=C2[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=S)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C2=NC(N([H])C3=C([H])C(=C([H])C([H])=C3S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C3=C(C([H])=C([H])C1=C3[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])=C(Cl)C([H])=N2
[H]N1C(=O)S[C@@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])[H])C([H])=C1[H]
[H]N([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])N2C1=NC(=C2C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(\N=N\C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C([H])C(N([H])C2=NC(=C([H])C([H])=N2)C2=C([H])C([H])=C([H])N=C2[H])=C1[H]
[H]\C(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])=C1/C(=NC([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N([H])C1=N[C@@](C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])C(=O)C2=C([H])N=C(OC([H])([H])C([H])([H])C([H])=C([H])[H])C([H])=N2)(C([H])([H])[H])C([H])([H])C([H])([H])S1
[H]C1=C([H])C(=C(OC(=O)C([H])([H])[H])C([H])=C1[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C(\C([H])=N\N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1Cl
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(C1=NC2=C(SC([H])=C2[H])C(=N1)C(=O)C1=C([H])C([H])=C(S1)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)C(\[H])=C(/[H])[C@]([H])(N(C(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])[C@@]1([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C2([H])[H]
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[H]OC(=O)[C@]12O[C@@](O[C@]([H])(C([H])([H])N([H])C(=O)N([H])[H])[C@@]1(O[H])C(=O)O[H])(C([H])([H])C([H])([H])C(=C([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(O[H])[C@@]2([H])OC(=O)C(\[H])=C(/[H])[C@@]([H])(C([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(OC2=C([H])C(Cl)=C([H])C([H])=C2Cl)=C(C([H])=N1)C(=O)N(C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]OC(=O)[C@]([H])(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]C1=C([H])C(=O)C([H])=C2N1C1=C(C([H])=C(Cl)C([H])=C1[H])C([H])([H])[C@]2([H])C([H])([H])[H]
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[H]OC(O[H])=C1C(=O)C(=O)C([H])=C([H])C([H])=C1C([H])([H])C(=O)O[H]
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[H]N([H])C1=NC(=C(C#CC(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C2=C(N1[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]S\C(=N/N=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C(=O)N(C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
O=C1C=C(OC2=C1SC=C2C1=CC=CO1)N1CCOCC1
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[H]OC1=C2C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C([H])C2=NC(=C1[H])C([H])([H])[H]
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[H]OC(=O)C(=N\O[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])\C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(OC(=O)C3=C([H])C([H])=NC([H])=C23)C([H])([H])C1([H])[H])C1=NN([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]O[C@@]1([H])C([H])=C([H])[C@@]2([H])[C@]3([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]22C4=C(O[C@@]12[H])C(=C([H])C([H])=C4C3([H])[H])C(=O)N([H])[H]
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[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2N=C([H])N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])[C@@]2([H])N(C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=NC4=C(C(=NN34)C3=C([H])C([H])=NC([H])=C3[H])C3=C([H])C(OC([H])([H])[H])=C(F)C([H])=C3[H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N=C(N([H])C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N2C(=O)N([H])C(=C(C(=O)N([H])[H])[C@]2([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])N(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(N=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H]
NC1=NC(=CC=N1)N1C=CC2=C1C=C(N=C2)C#N
[H]N(\C([H])=C(/[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C(Cl)C([H])=NC([H])=C1Cl
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])S(=O)(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])[C@]([H])(O[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])SC([H])([H])C4([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]