[H]OC1=C([H])C([H])=C([H])N(C1=O)C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
CNC1=NC(CC(F)(F)F)=C(S1)C1=CC=NC(NC2=CC=CC(O)=C2)=N1
[H]N1C(=S)S\C(=C(\[H])C2=C([H])C3=C(N([H])C(=N3)C3=NC(=C([H])C([H])=C3[H])C3=C([H])C(=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C1=O
[H]N(C(=O)[C@@]1([H])C([H])([H])N([H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H])C1=NC([H])=C(SC([H])([H])C2=NC([H])=C(O2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S1
[H]N([H])C1=NC([H])=C(C([H])=C1[H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C(C(OC([H])([H])C([H])([H])[H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(/[H])C2=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C1=O
[H]C1=NC(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])SC([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])S(=O)(=O)N([H])[H]
[H]OC(=O)C1=C(C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(F)(F)F)S(=O)(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C3=C(N=C([H])C([H])=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])=C21)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])N2C([H])=C([H])C([H])=C2C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])N1C([H])=NC2=C(SC(=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1N=C([H])C2=C(OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C([H])N=C12)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])C([H])([H])C3=C2C(OC([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC1=NC2=C(N1[H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C#N)C([H])=C([H])S1
[H]OC1([H])C([H])([H])C([H])([H])N(C2=C3N([H])C(=C([H])C3=NC(=N2)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=NC2=C(N1C([H])([H])C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C#N)C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C(C([H])=C(O[H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=NC(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1C#N)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2N=C2SC(=C([H])C2=C1N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C(=NOC([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C1([H])[H])N([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])[H])[C@]([H])(O[H])[C@]1([H])OP(=O)(O[H])O[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1C([H])([H])N1N=C([H])C([H])=C1[H])C1=NC([H])=C([H])O1
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])[C@@]([H])(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])N=C1[H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(\C([H])=C3/SC(=S)N([H])C3=O)C([H])=C2[H])C(=C1O[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])ON=C(C2=C(C([H])=C([H])S2)C([H])([H])[H])C2=C(C([H])=C([H])S2)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
COC1=C(F)C2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=CC4=C(NC(=O)N(C)C4)C=C3)C2=O)C=C1
[H]OC1=C(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])S1
[H]N(C(=O)C1(C#N)C([H])([H])C1([H])[H])[C@@]1([H])C2=NN(C(=C2OC([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C2C(=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
CN(C)C(=O)C1=CC=C(CN2CCC3=CC4=C(C=C3CC2)N=C(N)S4)C=C1
[H]OC1=C(C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C(=O)OC([H])([H])C([H])([H])[H]
CC1=CC=C(NC(=O)\C=C\C2=CC=C(O)C=C2)C=C1
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])SC1=NC(=C(N1[H])C1=C([H])C([H])=NC(N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1Cl)C(=N\C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])\N([H])OC([H])([H])[H]
[H]N(C1=NC(=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(\C([H])=C(/[H])S(=O)(=O)OC([H])([H])C([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C(S1)N(C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])N2C(=O)C3=C(ON=C3C3=C2C([H])=C([H])C([H])=C3Cl)C([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C([H])C(C#N)=C3[H])C([H])([H])[C@]2([H])C1([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(O[H])=C([H])C(\C([H])=C(\[H])Br)=C2O1
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])S(=O)(=O)N(C1=C([H])C([H])=C(C([H])=C1C#N)C([H])([H])[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1=C(Cl)C([H])=C([H])C2=C1OC([H])=C2[H]
[H]O[C@@]([H])(C([H])([H])N1N=C(C2=C1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C(SC3=C([H])C(F)=C([H])C([H])=C23)C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=NC(=C2C([H])=C([H])C(=O)N(C2=N1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])([H])O[H]
[H]C1=C([H])N=C(C([H])=N1)C1=NN=C(SC([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])S1
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])N1[C@@]2([H])C([H])=C(C3=C([H])SC4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N(C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N([H])S(=O)(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])([C@@]([H])(OC([H])([H])C(\[H])=C(/[H])Br)C(=O)N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])O[H])[C@@]([H])(O[H])[C@@]([H])(OC([H])([H])C(\[H])=C(/[H])Br)C1=NC(=NN1[H])C([H])([H])[H]
[H]C(=C1C2=C([H])C([H])=C([H])C([H])=C2SC2=C1C([H])=C([H])C([H])=C2[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])[C@](C2=C([H])C([H])=C([H])C(O[H])=C2[H])(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=NN(N=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC(=O)C(C)SC1=NN2C(C=C1)=NC=C2C1=CC=CS1
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C1OC1=C([H])C([H])=C(C([H])=C1Cl)C(F)(F)F)S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C1=NC2=C(N=C([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])[P@@](=O)(O[H])C([H])([H])P(=O)(O[H])O[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C(=O)N1[C@]([H])(C2=C([H])C(=C([H])C([H])=C2OC([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C2=C(C([H])=C1[H])\C(=N\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])\N=C1/N3C(=NC4=C1C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C3([H])[H])N1C(=N2)C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=NC(=C([H])C([H])=C1N([H])C1=C([H])N=C([H])N=C1[H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C(=NN1C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=N1
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[H]OC(=C(C#N)C#N)C1=C([H])C(O[H])=C(O[H])C(O[H])=C1[H]
C[C@H]1C2CC3=CC=C(C=C3[C@@]1(C)CCN2CC1CC1)C(=O)NCCC1=CC=C(C=C1)C1=CC=CC=N1
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[H]OC([H])([H])C([H])([H])ON([H])C(=O)C1=C([H])N(C(=O)C([H])=C1N([H])C1=C([H])C([H])=C(Br)C([H])=C1F)C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1N([C@]([H])(C([H])([H])[H])C([H])([H])OC(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N([H])[C@@]1([H])C(=O)N(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])C2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(=O)C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C2C([H])=C(N([H])C2=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]1([H])C(=O)N([H])C(=O)[C@](OC2=C([H])C([H])=C(OC3=C([H])C([H])=C(C([H])=C3[H])N3C([H])=C([H])C([H])=C3[H])C([H])=C2[H])(C1=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])[C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C2C(=O)N(C(=O)N([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3N=C([H])C([H])=NC3=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(I)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])N12)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C2=C(N([H])[C@]([H])(C(=O)N(C([H])([H])C(=O)N3C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]C1=C([H])C2=NC(=C([H])C([H])=C2O1)C([H])([H])OC1=C([H])C(=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])=C1[H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N1C(=NC2=C([H])SC([H])=C12)[S@](=O)C([H])([H])C1=NC([H])=C([H])C(OC([H])([H])C(F)(F)C([H])(F)F)=C1OC([H])([H])[H]
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])=C(C([H])=C12)[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])N1C([H])([H])[C@]2([H])C(=O)N(C3=C([H])C([H])=C(OC([H])([H])C(F)(F)F)C([H])=C3[H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H]
[H]N1C(=O)C([H])=C(C2=C([H])C([H])=C(F)C(F)=C12)C([H])([H])N(C(=O)C1=C([H])N=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C1=C(N(C(=O)C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(\C([H])=C2/C(=O)/C(=C(\[H])C3=C([H])C([H])=C(C([H])=C3[H])C(=N[H])N([H])[H])C([H])([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])=C1[H]
[H]N([C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C(=C([H])C([H])=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C2=C1N([H])C1=C2C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=C1[H])N1C(=O)C2=C(SC(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])N=C1C([H])([H])[H]
[H]ON([H])C(=O)[C@@]([H])(SC1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1[H])C([H])([H])C(\[H])=C(/[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]C1=C2OC(=O)N(C2=C([H])C(Cl)=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
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COC(=O)C1=CC2=C(NCC1)N=CN=C2NC1=CC(Cl)=C(OC2=CC=CC(=C2)C(F)(F)F)C=C1
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CC(C)(C)NC1=NC(Cl)=C2N([C@@H](CC2(C)C)C(=O)NCC2=CC=C(C=C2)C(N)=N)C1=O
[H]N(C(=O)C1=NC([H])=C([H])C(OC2=C([H])C([H])=C3N(C(=NC3=C2[H])N([H])C2=C(Br)C([H])=C([H])C([H])=C2[H])C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N1C(OC([H])([H])[H])=C2C3=C1C([H])=C([H])C([H])=C3C(=O)N([H])C([H])([H])C2([H])[H]
[H]N(C1=C2C([H])=NC([H])=C([H])C2=C(N=N1)C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)[C@]1([H])N(C2=NC(N3C([H])([H])C([H])([H])N(C(=O)C4=C([H])C([H])=C(C([H])=C4[H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])=C3C([H])=C(SC3=N2)C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C(\[H])=C(\[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[H]
[H]N([H])C1=NC(=NC(=N1)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
C[NH+](C)CCNS(=O)(=O)c1ccc(N\C=C2/C(=O)Nc3ccccc23)cc1
[H]OC1=C(Cl)C(=C(Cl)C([H])=C1[H])C1=C([H])C2=C([H])N=C(N=C2N(C1=O)C([H])([H])[H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]1([H])SC([H])([H])C([H])([H])N1C(=O)C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C1=C(C([H])=C([H])C([H])=N1)C(=O)C1=NC(=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N([H])[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
CCCCCN1C=C(C(=O)NC2CCCCCC2)C(=O)C2=C1ON=C2C
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[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N2C(OC([H])([H])[C@@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C1=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]O[C@@]1([H])[C@@]2([H])O[C@]([H])(C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC3=C([H])C(Cl)=C(C([H])=C23)C([H])([H])C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])[C@@]([H])(O[H])[C@]1([H])O[H]
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[H]OC(=O)C1=C([H])C2=C(N([H])C(=N2)N2C([H])([H])C([H])([H])C3(OC(=O)C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])=C1[H]
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[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H]
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[H]N([H])C1=C2C(=NC3=C([H])C(Cl)=C([H])C(Cl)=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
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[H]N([H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
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[H]N([H])C1=NC([H])=NN2C(=NC(=C12)C1=C(F)C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])N1N=C(C(=O)N([H])C1=O)C([H])([H])[H]
CC1=C(CCOCCO)C=C(N1C1=CC(F)=C(F)C=C1)C1=CC=C(C=C1)S(C)(=O)=O
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[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])SC1=C([H])N=C(S1)N([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C(=O)C([H])([H])N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[C@@]2([H])C([H])([H])[C@]2([H])C2([H])C([H])([H])C([H])([H])N(C3=NC([H])=C(Cl)C([H])=N3)C([H])([H])C2([H])[H])C([H])=C1F)C1([H])C([H])([H])C1([H])[H]
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[H]OC(=O)[C@@]([H])(N([H])C(=O)N([H])C1(C(=O)O[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]N(C([H])([H])[H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C(O[H])C([H])=C2[C@]1([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C([H])C(=C([H])C([H])=C2N=C1C([H])([H])[H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
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[H]N1C(=O)N(C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1=O
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[H]OC1=C([H])C([H])=C(\C([H])=C2/OC(=O)N(C2=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])=C1Br
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])N([H])C1=O)C1=C([H])C([H])=NC([H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C([H])C(=N1)C([H])([H])SC1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N1C(=C([H])C2=C([H])C([H])=C(Cl)N=C12)C(=O)N1C([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])O1)C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C1=NC([H])=C(O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
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[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])N([H])C1=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
CN1CCN(CC1)C1CC2=C(SC3=C1C=C(C=C3)C#N)C=CC=C2
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)N1N=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2N(C(=O)[C@@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(N=N1)C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N1C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C(C([H])=C3[C@]2([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(=NN1[H])C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H]
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[H]C([H])=C1C(=O)O[C@]2([H])[C@]3([H])O[C@]3(C([H])([H])[H])C([H])([H])C([H])([H])\C([H])=C(C([H])([H])[H])/C([H])([H])C([H])([H])[C@@]12[H]
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[H]N1C(=O)C([H])=C(C2=C1C([H])=C([H])C(=C2[H])N(C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]N(C(=S)N(C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)N1C(=O)[C@@]([H])(OC([H])([H])[H])[C@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C(Cl)=C(Br)C([H])=C2[H])C1=O
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N(C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])C([H])([H])C1=NN(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]N1C(=O)C(C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])=C(C1=O)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])N(N=C([H])C1([H])[H])C(=O)C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]C1=C([H])C(Cl)=C(N2C(=O)C([H])=C([H])C3=C2C([H])=C(N=C3C2=C([H])C([H])=C(F)C([H])=C2Cl)C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
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[H]N(C(=O)C1=NOC(=C1[H])C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])N1C(=NC(=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(F)C([H])=C1[H])C(F)(F)F
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[H]N(\C(=N/[S@](=O)C1=C(C2=C([H])C(Cl)=C([H])C([H])=C2S1)C([H])([H])[H])N1N=C([H])[C@]([H])(C([H])([H])C([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])C([H])=C([H])N=C2[H])=C([H])C([H])=C1[H]
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[H]C1=C([H])C([H])=C([H])C(=N1)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(C#CC3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC1=NC2=C([H])C([H])=C([H])C([H])=C2S1)C1=NC(=C([H])S1)C([H])([H])[H]
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[H]N([H])C1=NC2=NC([H])=C(C(=C2C(=N1)N([H])[H])C([H])([H])[H])C([H])([H])N([H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C(SC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]C1=C(SC2=C1N=C([H])N(C2=O)[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@]2([H])C([H])([H])N(C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C([H])N=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(OC(=O)C([H])([H])[H])C2=C3C(=C1[H])C([H])([H])[C@]1([H])[C@]4([H])C([H])=C([H])[C@]([H])(OS([O-])(=O)=O)[C@]([H])(O2)[C@]34C([H])([H])C([H])([H])[N@+]1([H])C([H])([H])[H]
[H]N([H])N1C(SC([H])([H])C(=O)N([H])C2=NOC(=C2[H])C([H])([H])[H])=NN=C1[C@@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
[H]C1=C(Br)C(Br)=C(S1)C(=O)C([H])([H])Br
[H]N1C(=O)C2=C3SC([H])=C([H])C3=C3N([H])C4=C(C([H])=C([H])C([H])=C4[H])C3=C2C1=O
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C(\N=C(/N([H])C#N)N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(\C(=N/S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])N1N=C([H])[C@@]([H])(C([H])([H])C([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
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[H]C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[C@@]1([H])O[C@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])N(C1=C2C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)[C@]1([H])N(C(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C1([H])[H])[C@]1([H])C2=NC([H])=C(Br)C([H])=C2C([H])([H])C([H])([H])C2=C1C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1=C(ON=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1Cl)N(C(=O)C([H])([H])[H])C1=C(SC(=C1C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])S2
[H]C1=C(N=C2C([H])=C([H])C(=C([H])N12)C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
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[H]N(C([H])([H])C([H])([H])OC1=C2N=C([H])N([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(F)C([H])=C2[H]
[H]N([H])C1=C([H])C2=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1O[C@@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C(C(=O)C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OP(=O)(O[H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])SC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2(N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C1=O
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[H]N([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1(OC([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]OC(=O)C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2O[C@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
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[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@](OC([H])([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])C1([H])C([H])([H])N(C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C(OC([H])([H])[H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
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[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C2=NC([H])=C([H])O2)C([H])=C1[H]
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[H]N1C2=NC([H])=C([H])C(=N2)C2=C([H])SC(=C2[H])C([H])([H])OC([H])([H])\C([H])=C([H])\C([H])([H])OC([H])([H])C2=C([H])C1=C([H])C([H])=C2OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C([H])=C2N=C([H])C(=C([H])C2=C1[H])C(=O)N([H])C([H])([H])C([H])([H])[H]
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[H]N(C1=C([H])C(Cl)=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(\N=C1/C(=O)N([H])N=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])[C@@]([H])(O[H])C([H])([H])N2[H])=C([H])C(O[H])=C1[H])C1=C([H])C(Cl)=C([H])C(I)=C1O[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]12[H]
[H]N([H])C1=NC2=C(C(=O)C3=C2C([H])=C([H])C([H])=C3[H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(\C(S2)=N\C(=O)C1=C(Cl)C2=C([H])C([H])=C([H])C([H])=C2S1)C([H])([H])C([H])=C([H])[H]
[H]OC(=O)C1=C([H])C(N([H])C2=C([H])C([H])=C(C([H])=C2[N+]([O-])=O)C(F)(F)F)=C([H])C([H])=C1[H]
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[H]ON([H])C(=O)[C@]([H])(OC1=C([H])C(=C(F)C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C(C2=NC([H])=C(C([H])=C2C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
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CC1CCC(CC1)=NNC1=NC(=CS1)C1=CC=C(C)C=C1
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[H]C#CC([H])([H])N1C(=O)N(C2=C(N(C(=N2)C2=C([H])C([H])=C([H])S2)C([H])([H])[H])C1=O)C([H])([H])[H]
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[H]C1=C(N=C(S1)C([H])([H])[H])C#CC1=C([H])C([H])=C([H])C([H])=N1
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[H]N=C(N([H])[H])C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C(=O)N([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(OC2=C(F)C(=C(F)C(=N2)N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])O3)C([H])([H])C2([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C1=NC(C2=C([H])C([H])=C([H])O2)=C(S1)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(C(=NC2=C([H])C([H])=C(F)C([H])=C12)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=C([H])C([H])=C([H])C3=C2C(=C([H])N3[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])SC([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N1C(=NN=C1C([H])([H])[H])C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C2=C(C([H])=C1[H])C1(C(=O)N2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(N([H])C(=O)C([H])([H])[C@@]1([H])O[C@]1([H])[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C1=C(N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NOC(=C1C(=O)N([H])C([H])([H])C([H])([H])OC1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C([H])C(Br)=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]O\N=C1/C2=C(C([H])=C(C([H])=C2[H])C2=C([H])N(N=C2C2=C([H])C([H])=C3N(N=C([H])C3=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2N(C([H])=C([H])C2=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C(F)=C2[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]N(C(=O)C1=C([H])C(=C(Cl)C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=NC2=C([H])C(=NN12)C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C([H])C(\C([H])=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C(OC([H])([H])[H])C([H])=C12
[H]\C(=N\OC([H])([H])[H])C1=C([H])C([H])=C(O[C@]2([H])OC([H])([H])[C@@]([H])(OC(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])[C@@]([H])(OC(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])[C@@]2([H])OC(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C4OC([H])([H])OC4=C3[H])C([H])([H])N(C(=O)C3=C(Cl)C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
O=C1C=C(OC2=CC=C3OCC=CC3=C12)C1=CC=CC=C1
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])[H])[C@@]([H])(N1C2=C(C([H])=C([H])C([H])=C2F)C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C(C(=O)C([H])([H])[H])C(=O)C2=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2O1
[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=NC2=C(O1)C([H])=C(Br)C([H])=C2[H]
[H]N(C1=NC([H])=C([H])C(=N1)N(C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])OC([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C1=NC([H])=NC2=C([H])C([H])=C([H])C(O[C@]([H])(C(=O)N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])[H])=C12
[H]C1=C(C([H])=C(N1C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N(C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=C1C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C1=C([H])N(N=C1[H])C([H])([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1C([H])([H])[H])C1=C(C2=C3N1C([H])([H])[C@]([H])(OC3=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=C([H])C([H])=N2)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1N=C([H])C([H])([H])[C@@]1([H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])N(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(O[C@@]3(C2([H])[H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]3([H])C([H])([H])C2([H])[H])N=C1[H]
[H]OC(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(I)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C(=O)[C@@]([H])(N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])S(=O)(=O)C2=C([H])C3=C(C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@](C([H])([H])N([H])C1=C2C([H])=NN(C2=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]OC1=C(C([H])=C(C([H])=C1Br)C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C(C2=C([H])C(=C([H])C([H])=C2N1[H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C([H])([H])C(=O)N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C2=C([H])C(OC3=C4C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C4=NC([H])=N3)=C([H])C([H])=C12
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1N([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC1=NC(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])C([H])(C(=N/OC([H])([H])C([H])([H])[H])\C4=C([H])C([H])=C(Br)C([H])=C4[H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(C(=O)C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2([H])C1([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N=C(N(C2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]OC(=O)C(C1=C([H])C([H])=C(Cl)C(N([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[C@@]3([H])OC4=C(C([H])=C([H])C([H])=C4[H])N(C([H])([H])[H])C3([H])[H])C([H])=C2Cl)=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(O[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C2=C([H])C(=C([H])C([H])=C2N=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=NN(C(SC([H])([H])C([H])([H])C([H])([H])[H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]C1=C([H])C2=C(C(=C1[H])N1N=C([H])C(Cl)=C(OC3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C1=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C2=C(N([H])C([H])=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=N1
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C1=C(OC(=N1)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C(F)(F)F)(C(F)(F)F)C(F)(F)F
[H]N(C(=O)C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2C2=C1C(=NC([H])=N2)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])([H])C1([H])[H])C(=O)OC([H])([H])[H]
[H]N([H])C1=C([H])C(=NC([H])=N1)N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])N([H])C1=C([H])C(N([H])C(=O)C2=C([H])C([H])=NC([H])=C2C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(=O)[C@]1([H])N(C([H])([H])C2=C([H])C(=C([H])C([H])=C2C1([H])[H])[N+]([O-])=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1N=C([H])C2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C([H])N=C12)C(=O)C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC2=C(C([H])=C([H])C(=C2S1)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2N(C(=O)N(C2=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C2N(C([H])([H])[H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3(C2=C1[H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])SC(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]N=C(N([H])C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])S1
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])C(=O)O[H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C2=C(S1)C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C2C3=C(C4=C(N3[H])C([H])=C([H])C(Br)=C4[H])C([H])([H])C(=O)N([H])C2=C1[H]
[H]C1=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=NC3=C2C([H])=C([H])N=C3[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2N1C(=O)N(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])OC([H])([H])[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])[C@]1(C2=C([H])C([H])=C([H])C(=C2[H])N2N=C([H])C([H])=C2[H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N(C1=C([H])C([H])=C([H])C(N(C([H])([H])C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C2=C(F)C([H])=C(F)C([H])=C2[H])=C1C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2O[C@@]1([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(\C([H])=C(/[H])C2=C(Cl)C([H])=C(OC([H])([H])C3=C(ON=C3C([H])([H])OC3=C(F)C([H])=C(F)C([H])=C3F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])=C1[H]
[H]C1=C([H])C(Br)=C([H])N2C1=NC(=C2C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])OC(=O)N1C1=C([H])C([H])=C([H])C([H])=C1F
[H]SC([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])N1N=C(C(=C1[H])C1=C([H])C([H])=C2C3=NN([H])C([H])=C3C([H])([H])C2=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]\C(=N/OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(S1)C([H])=NC([H])=C2SC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(O[H])C([H])=C(O[H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C#N)C([H])([H])C1=C(F)C([H])=C(C#N)C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])N([H])[C@@]([H])(C2=C([H])N([H])C3=C2N=C([H])N([H])C3=O)[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)C1=C(O[H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C(C([H])=C2N1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N([H])[H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(F)=C([H])C(F)=C([H])C2=NC2=C1[C@]1([H])C([H])([H])C(=C([H])[C@]([H])(C2([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])OC1=C([H])C([H])=C(Br)C([H])=C1C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C1=C([H])SC([H])=C1C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])\N=C2/C(=O)N([H])C3=C([H])C(=C([H])C([H])=C23)C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])[H])C([H])([H])N(C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])[H])=N1
[H]N(C([H])([H])[H])C([H])([H])C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C(=NN2C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(SC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[S@](=O)C([H])([H])[H])=NC(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])N(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=NN2[H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=NC3=C(C(=NN13)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(Cl)C(OC([H])([H])[H])=C1[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])N(C1=O)C([H])(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])N3C(=O)C4=C(C([H])=C([H])C([H])=C4[H])C3=O)[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]\C(=C(\[H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C([H])=C(C(=O)O2)C([H])([H])[H])C1=C([H])C(=O)C(O1)(C([H])([H])[H])C([H])([H])[H]
CC(C)OC1=NC=C(C=C1Cl)C1=NC2=C(O1)N=CC(CCCCCC(O)=O)=C2
[H]OC([H])([H])C(=O)N([H])C([H])([H])C([H])([H])N1C(=O)C(=NC2=C([H])C([H])=C(N([H])C([H])([H])C3=C([H])C(=C([H])C([H])=C3[H])C(F)(F)F)C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)C1=NN=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C(=O)[C@]([H])(N([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[S@](=O)C([H])([H])C1=C(OC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=NC2=C(N1[H])C(=C([H])C([H])=C2[H])C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C(C([H])=C([H])C([H])=C1[H])C1(C([H])([H])N([H])C(=O)N([H])C2=C(C([H])=C([H])C([H])=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NN([H])C2=C1C(=C([H])C([H])=C2OC([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]2(OC([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[H])C(=C1O[H])C([H])([H])C1=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@]2([H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N2C(=NC(=C2C2=NN(C(=O)C([H])([H])C2([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])=C1[H]
[H]O[C@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]1([H])N2C(=O)[C@@]([H])(N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])N(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]1([H])N2C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])[H]
[H]C1=C([H])C(=C([H])C(=C1F)C(F)(F)F)C1=C([H])C(=NC(=N1)C#N)C([H])([H])C([H])([H])C([H])([H])[H]