[H]N1C(=C([H])C(=NC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]O[P@](=O)(C([H])([H])[H])[C@]([H])(C(=O)N([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])OC([H])([H])[C@]2([H])C3([H])[H])=C2C([H])=NN(C2=N1)C([H])([H])C(F)(F)F
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C2=C(N=C(N=C2C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])S2(=O)=O)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=C3C(N([H])C([H])=C3C([H])([H])C([H])([H])C3=C([H])C([H])=C4OC([H])([H])C([H])([H])C4=C3[H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1F)C1([H])C([H])([H])C([H])([H])N(C(=O)C2=NC([H])=C([H])C([H])=C2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])[C@@]([H])(N([H])[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
OC(=O)C1=NOC(=C1)C1=CC=C(OCC2=CC=C(Cl)C=C2)C(=C1)N(O)=O
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])=C(C3=C([H])C([H])=C([H])C([H])=C3C(F)(F)F)C([H])([H])C2([H])[H])C([H])=C1[H]
CC1=CC=CC(F)=C1NC(=O)C1=NC2=C(NS(C)(=O)=O)C=CC=C2C(O)=C1
[H]N(C(=O)C([H])([H])SC1=NN=C(N1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C(=O)S[C@@]([H])(C1=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC2=C(C([H])=C(OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]1([H])N(C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(S[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(C([H])=C([H])C(=C1[H])C1=NN=C(OC([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=NC([H])=C([H])N2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OP(=O)(O[H])O[H])C([H])=C1[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OP(=O)(O[H])O[H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(\N=C1/C(=O)N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N1C(=O)C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])[H])N(N=C2SC([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]2([H])N(C([H])([H])SC2([H])[H])C1([H])[H])C(=O)O[H]
[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@]2([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C3C1=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])=C(C(=O)N=C1SC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C2=C(C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])[H])C([H])([H])C2=NC(N([H])[H])=C([H])C([H])=C2[H])C([H])([H])N(C1=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@@]([H])(N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C(F)=C1[H]
[H]N(C(=O)C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C([H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=NSC(N([H])C2=C([H])C([H])=C(N([H])C3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])=C2[H])=C1C(=N[H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1C1=C(C([H])=C([H])C([H])=C1[H])N2C([H])([H])[H])C1=C([H])C(Br)=C([H])C([H])=C1[H]
CC(C)(C)NC(=O)NC1=CC=CC(=C1)C1=CSC2=C(C=NC(N)=C12)C1=CN=CC=C1
[H]N(C1=NN=C(C([H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
Nc1nccc(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C2=O)C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C2=NC3=C(N2[H])C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]C1=NN(C2=C1C([H])([H])C([H])([H])C([H])([H])C1=C(OC(=C21)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(O[C@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC2=NC(=NC([H])=C2C([H])=C1C1=C(Cl)C([H])=C([H])C([H])=C1Cl)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])SC1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])[H]
[H]N([H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NN2C(N=C([H])C([H])=C2C2=C([H])C(OC([H])([H])C3([H])C([H])([H])C3([H])[H])=C(OC([H])(F)F)C([H])=C2[H])=C1[H]
[H]ON([H])C(=O)C1=C([H])C2=C([H])C(=C([H])C([H])=C2S1)C([H])([H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)[C@@]2([H])OC3=C(C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C1C([H])=NN2C([H])([H])[C@]([H])(Br)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(OC([H])([H])C3=C(F)C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
[H]N(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N([H])C1=C2C(=O)C3=C(N([H])N=C3C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(S1)C(=O)N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OC1=NC(=NC2=C1N=C([H])N2C([H])([H])C1=C(Cl)C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])N([H])[H]
[H]N([H])C(=S)N1N=C(C([H])([H])[H])[C@@]([H])(\N=N\C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
[H]N([H])C(=O)[C@@]1([H])N(C(=O)C(\[H])=C(/[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]2(ON=C(C3=C([H])C(N([H])C(=O)C(=C([H])[H])C([H])([H])[H])=C([H])C([H])=C3[H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(O1)C(=C([H])C(C#N)=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(S1)[C@]([H])(OC([H])([H])C1=C(C([H])=C(C#N)C(=O)N1C([H])([H])[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])[H])C2([H])[H]
[H]N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])OC(=O)C2=C([H])C([H])=C([H])C3=C2N=C([H])N3[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
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[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCO
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[H]N([H])C(=O)C([H])([H])C([H])([H])N1C(=NC2=C([H])C(=C([H])C([H])=C12)N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H])N([H])C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C(Cl)C([H])=C1Cl)S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C1=C([H])C([H])=C2N(C(=O)N([H])C([H])([H])C2=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)S(=O)(=O)C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]\C(=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C(Br)C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2N=C1[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=NC2=C(C([H])=C([H])C([H])=C2N1C1=C([H])C(OC2=C([H])C([H])=C([H])C(=C2[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C([H])C([H])=C1Cl)C(F)(F)F
[H]N([H])C1=NN(C2=C1C(=C([H])N=C2[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C(=C([H])C([H])=C2F)C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C(S2)C(C(=O)N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(\N=N\C2=C(O[H])C([H])=C(C3=C2C([H])=C([H])C([H])=C3[H])S(=O)(=O)O[H])C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
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[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C3=C(Cl)C([H])=NC(=C3[H])N3C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])N(N=C4[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C21)C1=C([H])C(F)=C([H])C([H])=C1[H]
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[H]OC1=C([H])C(=C([H])C(O[H])=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C(=C([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC1=C(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C(O[C@]2([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]2([H])O[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C(SC2=C1C([H])([H])[C@]([H])(OC([H])([H])[H])O[C@]21C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C2=C1N(C([H])=C2C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])S1
[H]N(C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(N([H])C2=NC([H])=NC3=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C([H])=C1[H]
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[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])OC(=O)N(C1=O)C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]OC(=O)[C@@]1([H])[C@@]([H])(N(C([H])([H])C(=O)N([H])C2=C(C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C2=C1OC(=C([H])C2=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])N1C(=O)N(C2=C([H])C([H])=C(C([H])=C12)C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]ON1C([H])([H])C([H])([H])C([H])([H])[C@@](N([H])C([H])([H])[C@@]([H])(O[H])[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C(F)=C([H])C(F)=C2[H])(C2=C([H])C([H])=C([H])C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N(\N=C(\C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H])C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C(=O)C2=C(N(C(=N2)C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
CCC1=NC2=C(N1[C@H]1CCC3=C1C=CC(=C3)C1=CC=CC=C1C1=NN=NN1)C(=O)N(CC1=C(OC(F)(F)F)C=CC=C1)C=C2
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])([H])[C@@]1([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C12)C(F)(F)F
[H]N(C1=NC(=C([H])C([H])=N1)C1=C(N(C([H])=N1)C([H])([H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)C1=NN=C(O1)C(C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])C#CC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(N([H])C(=O)C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2[H])N(C2=C([H])C3=C(C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])C(=O)OC([H])([H])[H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[C@@]([H])(O[H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(C3=NC4=C(N3[H])C(=O)N(N=C4C([H])([H])[H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C(=C(C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
CNC(=O)NC1=CC=C(OC2=NC=NC3=C2N(C)C=C3)C=C1
[H]OC(=O)C(\[H])=C(\C1=C([H])C2=C(N([H])N=C2C([H])=C1[H])C1=C(OC([H])([H])C([H])([H])[H])C(=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])O\N=C(/C2=C([H])C([H])=C([H])C(Cl)=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])N1C(=NC(=C1C(=O)C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C2C(=C([H])C(=C1[H])C([H])([H])[H])N(C(=O)C2([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(OC([H])([H])[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])C1=C2C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C([H])=C1C1=C([H])C([H])=NC2=C1C([H])=C([H])N2[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N=NN1C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])=C(C#CC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(O[H])N=C(N=C2C([H])=C1[H])C(F)(F)F)C(=O)O[H]
[H]N1N=C(C2=C([H])C([H])=C([H])S2)\C(=C(/[H])C2=C([H])N(C3=C2C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C3[H])C([H])([H])[H])C1=O
[H]C1=C([H])C(=C([H])C([H])=C1C#N)C1=C([H])C2=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]3([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]13C([H])([H])C2([H])[H]
[H]C1=NC(OC([H])([H])[H])=C(N=C1[H])[C@@]([H])(C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C12)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])C(=O)N(C([H])([H])[H])[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC1=C2N([H])C(=NC2=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C(N(C2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC([H])=C1C1=C([H])C(N([H])[H])=C([H])C(N([H])[H])=C1[H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C(=C12)C([H])([H])[H])C([H])([H])[C@@]([H])(OC(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(SSC2=C(C(=O)N([H])[H])C3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])[H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C(Cl)C(=C(Cl)C([H])=C2[H])C([H])([H])OC2=C([H])C([H])=C([H])N3C(Br)=C(N=C23)C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C(=N[C@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C(F)=C2[H])C1=O)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])[C@]3([H])C([H])([H])[C@]3(C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(C2=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=N3)=C2[H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C(OC([H])([H])[H])C([H])=C1[H])C1=C(C(=C([H])C([H])=C1[H])C([H])([H])N1N=C([H])C(=C([H])C1=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C1=C([H])N=C([H])C(=C1[H])C1=C([H])N=C2N([H])C([H])=C(C2=C1[H])C1=C([H])N=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C(C(OC([H])([H])C(F)(F)F)=N1)C1=C([H])C(=C(Cl)C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C(F)=C1F
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C3([H])[H])[C@@]1([H])OC([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]N(C(=O)N1C2=C([H])C([H])=C(Cl)C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C(Cl)N(C2=NC(=C(N12)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C(F)(F)F)C(F)(F)F)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]