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[H]N1C([H])=C([H])C2=C([H])C([H])=C(C([H])=C12)C1=C([H])C(=C2N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]([H])(C2=C1Cl)C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])SC(=N1)C1=C(SC([H])([H])[H])SC(=C1[H])C(=N[H])N([H])[H]
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[H]OC([H])([H])C([H])([H])N(C1=C2C(SC3=C2C([H])=C([H])N(C3=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=NC([H])=C1[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C1C(=O)N2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=C(C([H])=C(Cl)C([H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]O[C@@]([H])([C@@]([H])(OC([H])([H])C(\[H])=C(/[H])\C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]1([H])O[H])[C@@]([H])(O[H])[C@@]([H])(OC([H])([H])C(\[H])=C(/[H])\C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])O[H]
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[H]N(C([H])([H])C1=C([H])SC(=N1)C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C1\SC(=NC1=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]OC(=O)C([H])([H])C1=C([H])SC2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])OC3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)=C([H])C([H])=C12
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])([H])C1([H])[H])C(OC1=C2C(OC([H])([H])[H])=C([H])C(=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C2N=C(C([H])=C([H])C2=C1[H])N1C([H])([H])[C@]2([H])OC([H])([H])[C@@]1([H])C2([H])[H]
[H]N=C(SC([H])([H])C([H])([H])C([H])([H])N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N([H])C1=O)N([H])[H]
[H]N(C(=O)C1=C(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])F
[H]N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])N=C12
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C(=O)N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C1=NC2=C(N([H])C([H])([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C2=C(C([H])=C([H])N=C2N1[H])C1=C([H])N(N=C1C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C(\[H])=C(/[H])[C@@]1([H])[C@]([H])(O[H])C([H])([H])[C@]([H])(O[H])[C@]1([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])P(=O)(O[H])O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC([H])=NC2=C1N=C(SC1=NC3=C(S1)C(Cl)=C([H])C([H])=C3[H])N2C([H])([H])C([H])([H])C([H])([H])OC(=O)C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=C([H])C(N=[N+]=[N-])=C2[H])C([H])([H])N=[N+]=[N-])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2S1
[H]OC(=O)C1=C([H])C([H])=C([H])C(=N1)C(=O)N([H])C1=C(Cl)C(Cl)=C(C([H])=C1S(=O)(=O)N([H])[H])S(=O)(=O)N([H])[H]
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[H]OC1=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)[C@]([H])(O1)C([H])([H])OS(=O)(=O)C([H])([H])[H]
[H]N(\N=C(\[H])C1=C([H])C([H])=NC([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(F)C([H])=C1[H]
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[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=NC([H])=C1[H])C1=C([H])C([H])=C(Cl)S1
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[H]N1C([H])=[N+](C(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])OC1([H])[H]
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[H]N(C1=NC2=C(C([H])=N1)C([H])([H])C(=S)N([H])C1=C([H])C(Cl)=C([H])C([H])=C21)C1=C(C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
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[H]N=C(N([H])[H])N([H])C(=O)C1=NC(Cl)=C(N=C1N([H])[H])N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
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[H]OC1=NC2=C3N1C([H])([H])[C@]([H])(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C2[H]
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[H]OC([H])([H])C([H])([H])\N=C1\SN(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C(=N[C@@]([H])(N([H])C(=O)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C([H])([H])[H])[C@]1([H])C2=C([H])C(=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C(\N([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]N([H])C1=NC([H])=NC2=C1C(=C(N2C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(N(C3=C([H])C(F)=C(F)C([H])=C3[H])C([H])([H])N([H])C2=O)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])S[C@@]([H])(N(C1=O)C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
CN1CCN(CC1)C1CC2=C(SC3=C1C=C(C=C3)C1=CN=CN=C1)C=CC=C2
[H]N([C@@]1([H])C([H])([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2N=C(C3=C2C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(F)(F)F)C1([H])[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]C(=O)C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(F)C([H])=C1C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]2([H])N3C4=C(SC([H])([H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C4[C@]2([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C2=NC(C3=NN=C(S3)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C(N2C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])[H])C(Cl)=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=C([H])C(=NC2=O)N([H])[H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@@]([H])(C1=C(Cl)C([H])=C([H])C([H])=C1[H])C(C(=O)OC(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)O[C@]1([H])C2=C(C([H])=C3OC([H])([H])OC3=C2[H])[C@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])[C@]2([H])C(=O)OC([H])([H])[C@@]12[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C(C2=C([H])C([H])=C([H])C([H])=C2S1)[C@]([H])(C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H]
[H]N(\C(N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C(\[H])[N+]([O-])=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1N=C(C2=NC3=C(N2[H])C([H])=C([H])C([H])=C3C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=C([H])C(=C([H])N=C12)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])N=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C(C#N)=C2[H])[C@]1([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N(C1=NC2=C(N=C([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(SC1=NC(N([H])C2=C(C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])=C([H])C(Cl)=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=NOC(=N1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C12
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N(C2=NC3=C([H])C([H])=C([H])C([H])=C3C(=C2C1=O)C([H])([H])[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C(SC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C1=O
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C(N=C3C([H])=C(N=C(N23)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
C[C@H](CC1=CC=C(OCCCCCCCCCCNC2=C3C=CC=CC3=NC3=C2CCCC3)C=C1)N(C)CC#C
[H]OC1=C([H])C([H])=C2N=C([H])N(C2=N1)C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)C4=C([H])N([H])C5=C4C([H])=C([H])C([H])=C5[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=NC(=NC(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C12)C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]C([H])=C([H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2C2=C1C1=C(N([H])C(C([H])=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(N([H])C1=C([H])C([H])=C(OC3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C2([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=O)\C2=N\C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])[C@@]([H])(OC([H])([H])C1=C(C([H])=C(C#N)C([H])=C1[H])C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N=C1[H])C#N
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)N([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C(=C([H])C([H])=N1)C([H])([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]OP(=O)(O[H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])SC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2(N([H])C1=O)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[H]
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[H]N(C1=C([H])C([H])=C(Br)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]OC([H])([H])C([H])([H])N(C1=NC(N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C2N=C(N=C(N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=N1)N(C([H])([H])C([H])([H])O[H])C([H])([H])C([H])([H])O[H])C([H])([H])C([H])([H])O[H]
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[H]ON([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])O[C@@]([H])(C([H])([H])C([H])([H])N([H])[H])C1([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])(C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C#CC([H])([H])\N=C(\N([H])[H])N([H])[N+]([O-])=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])N(C(=O)N1OC(=O)C(=C1C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N(C(=O)OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]([H])(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C([H])([H])C2=C([H])C([H])=C([H])C(I)=C2[H])[C@]1([H])O[H]
[H]OC1=C([H])C([H])=C(C(O[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(O[H])C(=C1[H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])[N+]([O-])=O)C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C(SC2=C1C(=O)C(=C([H])N2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(OC2=C([H])C3=C(OC(=N3)N([H])C3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])=C2[H])=C([H])C([H])=N1)C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])S[C@@]([H])(N(C1=O)C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N2N=C(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(Cl)=C2C([H])([H])[H])C(=C1[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C(I)=C([H])C2=C1[H]
NCCc1c[nH]c(n1)-c1cccc(Cl)c1
[H]OC(=O)C([H])([H])N1N=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N=C(N([H])[H])C(=N1)C(=O)N([H])[C@]1([H])[C@@]2([H])C([H])([H])[C@@]3([H])C([H])([H])[C@]1([H])C([H])([H])[C@](O[H])(C3([H])[H])C2([H])[H]
[H]N(C1=C(C(=C([H])C([H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C2=C(C([H])=C(C(Cl)=C2[H])S(=O)(=O)N([H])[H])S(=O)(=O)N1[H]
[H]N([H])C1=NC(=C([H])S1)C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]2([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])OC(=O)C1=C(C([H])([H])OC(=O)C([H])([H])[H])C([H])([H])S(=O)(=O)[C@@]2([H])N1C(=O)[C@]2([H])OC([H])([H])[H]
[H]N(C(=S)N([H])C([H])([H])C([H])([H])N(C1=NC([H])=C(Br)C([H])=C1[H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C2N([H])N=NC2=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC(=O)C1=C([H])C([H])=C(C(I)=C1[H])C([H])([H])[H]
[H]N(\N=C1/C(=O)N([H])C2=C([H])C([H])=C3N=C([H])SC3=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])S(=O)(=O)N([H])C([H])([H])[H]
CC(C)N1CCC(CC1)OC1=CC=C2N3CCN(CC(F)(F)F)C(=O)C3=CC2=C1
[H]OC1=C([H])C([H])=C(C([H])=C1Cl)C(=O)N([H])\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
Cc1csc(Nc2ncc(C)c(n2)-c2c[nH]c(c2)C(=O)N[C@H](CO)c2cccc(Cl)c2)n1
[H]N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=CN(C=N1)C1=CC(C)=CC(NC(=O)C2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)=C1
[H]N1[C@@]2([H])C(C(=O)N(C([H])([H])C3=C(Cl)C(Cl)=C([H])C([H])=C3[H])C3([H])C([H])([H])C3([H])[H])=C(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])OC4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])[C@]1([H])C([H])([H])N(C(=O)C([H])([H])[H])C2([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@@](=O)(O[H])O[P@@](=O)(O[H])O[P@@](=O)(O[H])OC([H])([H])[C@@]2([H])O[C@@]([H])(N3C([H])=C([H])\C(=N\OC([H])([H])[H])N([H])C3=O)[C@]([H])(O[H])[C@]2([H])O[H])[C@@]1([H])O[H])N1C([H])=C([H])\C(=N\OC([H])([H])[H])N([H])C1=O
[H]\C(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])=C1\C([H])([H])N2C3([H])C([H])([H])C([H])([H])[C@]2([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@]1([H])C3([H])[H]
[H]N=C(N1C([H])([H])[C@]2([H])C(=O)C([H])([H])C([H])([H])C(C3=C([H])C([H])=C([H])C([H])=C3[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]2([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1C1=C(N([H])C(=O)C2=C(C3=C(O2)C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C(=NO1)C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C(=N1)N(C([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([C@@]1([H])C(=O)N([H])[C@@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(N=C(N(C3=C([H])C([H])=C(C#N)C([H])=C3[H])C2=O)[C@@]([H])(N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C(=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]C1=C([H])C(=NN1C1=C2C(=NC(=C1[H])C([H])([H])[H])N(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])C2([H])[H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(SC([H])=C2C2=C([H])N=C([H])C([H])=C2[H])=C(C([H])=N1)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]SC([H])([H])[C@]([H])(N([H])[H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C([H])=C(Cl)C(=C2[H])C([H])([H])C2=NN=C(S2)C2=C([H])N=C(C([H])=C2[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])N2C(=O)N(C(=O)[C@]12[H])C1=C(Cl)C(=C(C#N)C([H])=C1[H])C([H])([H])[H]
[H]C1=C(N=C(N1C([H])([H])[H])C([H])([H])C([H])([H])C1=NN2C(=N1)C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1(O[H])C2=C(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])=C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(Cl)=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])C(=C([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
CCNC(O)[C@@]1(CC2=CC=CC=C2)CCCN(C1)C(=O)[C@@H](CC1=CNC2=C1C=CC=C2)NC(=O)C(C)(C)N
[H]OC([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C1=C(N([H])[H])N(N=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C2=NN=C(N2C([H])([H])[H])C2(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]C([H])(N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])[C@@]12[C@@]3([H])[C@]4([H])[C@@]5([H])[C@@]([H])([C@]14[H])[C@]2([H])[C@@]35[H]
[H]N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C1=C([H])N([H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C1=C([H])C(=NC2=C3C(=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C1(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C(N=C(N1C1=C([H])C(OC([H])([H])C(F)(F)F)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)C2=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N2N=C([H])C(=C2N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C2N(C3=C(C2=C1[H])C([H])([H])[C@]([H])(C([H])([H])C3([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=C(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C(N(N=C1C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])[H]
Cc1cnc(NN2CCCCC2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
[H][C@]1(CN(C(=O)OCC=C)C1=O)[C@@H](C)OC(=O)COCC1=CC=CC=C1
[H]OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C3=NC([H])=NC(N([H])C4=NN([H])C(=C4[H])C([H])([H])C(=O)N([H])C4=C([H])C([H])=C([H])C([H])=C4[H])=C3C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N2N=C(N=C2C(=N1)N([H])[H])C1=C([H])C([H])=C([H])O1
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C2C(=NN([H])C2=N1)N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(N([H])C2=NC3=C(N=C2[H])C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C([H])=O
[H]C1=C([H])C([H])=C(O1)C([H])([H])N1C2=C(N(C(=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(=O)N(C1=O)C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(OC(=C1[H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1OC1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(=NN2C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])N=C3C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)OC([H])([H])C([H])=C([H])[H])C(=O)C([H])([H])OC1=C(C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C(=O)OC([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C1=C2N=C(C([H])=NC2=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C(=C1[H])N1C(=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C(=O)OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])C3([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H]
[H]N1N=C(N=C1C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(I)S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N(C1=C(Cl)C(=C(Cl)C([H])=C1[H])C([H])([H])OC1=C2N=C(SC2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1(C(=O)OC([H])([H])C2=C1C([H])=C1N(C2=O)C([H])([H])C2=C(C3=C([H])C(=NC([H])=C3N=C12)C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])C2=C([H])N(N=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])=C([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
CCCNC(=O)C1=CC=C(F)C(=C1)C1=C2C=CC(OC3=CC=C(F)C=C3F)=NN2C=CC1=O
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=NN=C2SC([H])([H])C(=NN12)C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]S[C@@]1([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])N([H])C([H])([H])C2=C(F)C([H])=C([H])C(F)=C2[H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=O
[H]C1=C([H])C2=C3N(C([H])([H])C2([H])[H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3=C1[H]
[H]OC(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C(OC([H])([H])[H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[S+]([O-])(=NC(=O)C([H])([H])N([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C(Cl)C([H])=C1[H]
[H]N(C1=C2C(SC3=C2C([H])=C([H])N(C3=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=NC([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])[C@@]1([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]C1=C([H])C(N(C([H])([H])[H])C([H])([H])[H])=C(C#N)C(=C1[H])N(C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N(C([H])([H])C(=O)N([H])C1=NC(OC([H])([H])C([H])([H])[H])=C(C#N)C(N([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O\C(OC([H])([H])[H])=C1\C(=NC(=C(C(=O)OC([H])([H])[H])[C@@]1([H])C1=C([H])C(N([H])C(=O)N([H])C([H])([H])C([H])([H])N([H])C2([H])C([H])([H])C([H])([H])N(C3=C(OC(F)(F)F)C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N([H])C([H])([H])C#N)=C(C([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C(N(C1=S)C([H])([H])[H])C([H])([H])SC1=NC2=C([H])C([H])=C([H])C([H])=C2S1
[H]N(C1=C([H])C2=C(C([H])=C1[H])C(C([H])=C2C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C(Cl)N=C2SC([H])=C([H])N12
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[H]N(C(=O)C([H])([H])[H])C1=NN([H])C2=NC([H])=C(C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]1([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C(=O)N([H])C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C2C([H])=C([H])C([H])=C(C2=NN1[N+]([O-])=O)[N+]([O-])=O
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[H]C([H])([H])N1C2=C(N(C(SC([H])([H])C(=O)N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=N2)C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N(C1=O)C([H])([H])[H]
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[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2N=C(C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C3=C(C([H])=C([H])C([H])=C3[H])C2=O)C([H])([H])C1([H])[H]
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[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C([H])=C(F)C(Cl)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(OC3=C2OC2=C(C3=O)C(O[H])=C([H])C(O[H])=C2[H])C(Br)=C1[H]
[H]C1=C(N(N=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=S)C([H])([H])O1)C([H])([H])C([H])([H])C#N
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[H]N1C([H])([H])C([H])([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])OC([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(=C([H])C([H])=C2O1)C(=N[H])N([H])[H]
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[H]ON([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=NC2=C1C([H])=C([H])C([H])=C2[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)OC([H])([H])C([H])([H])OC(=O)[C@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])=C([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C(N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C(=C([H])O1)[C@@]1([H])OC(=O)[C@]2([H])C([H])([H])C([H])([H])[C@]3(C(=C([H])[C@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@]3([H])[C@@]2(C([H])([H])[H])C1([H])[H])C(=O)OC([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(C#N)=C([H])N=C2C([H])=C1[H]
[H]N(C(=O)C1=C(C(=NC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])N=C([H])C([H])=C1[H])[S@](=O)C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)[N+]([O-])=O)C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C(=NN2C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2Br)C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NO[C@@](C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2SC([H])([H])[H])(C([H])([H])C(=O)OC([H])([H])[H])C1([H])[H]
[H]OC1=C2N(N=C(C2=NC(=N1)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1C(=C(N2[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C(=O)N([H])C1=NN=C(S1)S(=O)(=O)N([H])[H]
[H]OC(=O)C(OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=NN(C(=O)N1C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C([H])=C(OC3=NC4=C([H])C([H])=C([H])C([H])=C4S3)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(S1)C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])SC([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C2([H])[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N(C2=C(C(N([H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]N(C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1N=C([H])C2=C1C([H])=C([H])C(=C2[H])C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]C1=C(C([H])=C2SC(=NC2=N1)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])N=C(F)C([H])=C1[H]
[H]OC(=O)C1=C([H])C(OC([H])([H])[H])=C(C(O[H])=C1OC1=C(C(O[H])=C([H])C(=C1C(=O)O[H])C([H])([H])[H])C([H])([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])O[C@]1([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=C(C#N)[C@](C2=C([H])C([H])=C(F)C([H])=C2[H])(C(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(=C(S1)C1=NC(=NO1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C1=C(N=C(O1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])N1C2=C(OC([H])([H])[C@@]1([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(N([H])C(=O)C([H])=C1C(F)(F)F)C([H])=C2[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C(F)(F)F)C([H])=C1[H]
[H]N1C(=O)C(=O)N([H])C2=C([H])C(OC3=C([H])C4=C(N([H])C(=O)C(=O)N4[H])C([H])=C3[H])=C([H])C([H])=C12
[H]N=C(N([H])[H])N([H])C(=O)[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]N(C1=C([H])C(=NC2=C(C#N)C([H])=NN12)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]N1C(=C(C(=O)OC([H])([H])[H])[C@@]([H])(C2=C(F)C([H])=C([H])C([H])=C2[H])C(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C(\[H])=C(/[H])C(=O)N([H])[C@]([H])(C1=NC2=C(C(=C([H])S2)C([H])([H])[H])C(=O)O1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])[H])[C@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2O[C@]2(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
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[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1(C(=O)N([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])OC2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC2=C(OC3=C([H])C([H])=C([H])C(=C23)C(F)(F)F)C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@](C1=C([H])C([H])=C(Cl)C([H])=C1[H])(C1=C(C([H])=C([H])C(Cl)=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
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[H]C1=NN(C(=O)N1C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=N1)[N+]([O-])=O
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C(=C2[H])[C@]2([H])OC3=C(N=NC(SC([H])([H])[H])=N3)C3=C(C([H])=C([H])C([H])=C3[H])N2C(=O)C([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(N([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C(N=C1[H])C([H])=C(C([H])=C2[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(C(=O)C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C1=C([H])C(=O)N(C2=C1C([H])=NN2C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])S1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(N([H])C2=NC3=C(Br)C([H])=NN3C(=N2)N([H])C2([H])C([H])([H])C2([H])[H])=C1[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)[C@]([H])(SC1=NN=C(N1C([H])([H])[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(S1)C([H])([H])N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])[C@@]([H])(O[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C(C1=C([H])C(=C([H])C([H])=C1[H])C(=N\OC([H])([H])[H])\C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)[C@@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(C#N)C(=C1[H])C(F)(F)F)C([H])([H])[H]
[H]C1=C([H])N2N=C(N=C2C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NOC2=C([H])C([H])=C([H])C(=C12)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C(=O)N([H])N([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)[C@]([H])(N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC1=C([H])C([H])=C2O[C@]3([H])C([H])([H])N(C([H])([H])[C@@]([H])(O[H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])[C@@]3(C2=C1[H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C2([H])[H])S(=O)(=O)C1=C([H])C([H])=NC([H])=C1[H]
CCN1CCN(CC1)C(=O)C1CCC(=O)N1C1=CC=C(C=C1)C#C[C@]1(CN2CC3=C(C2=O)C(F)=C(OC)C=C3)NC(=O)NC1=O
[H]N(C(=O)C1=C(C([H])=C([H])S1)S(=O)(=O)N([H])C1=C(Br)C(=NO1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])S[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=C([H])C2=C([H])C(F)=C([H])C([H])=C12)C(=O)N([H])C([H])([H])C1=C([H])C([H])=[N+](C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])SC2=C([H])C(OC([H])([H])C3=NOC(=C3[H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C([H])C([H])=C12
[H]N(N1C(=S)S\C(=C(\[H])/C(=C(\[H])C2=C([H])C([H])=C([H])C([H])=C2[H])/C([H])([H])[H])C1=O)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C(=O)OC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C12
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(Cl)C(=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(=C([H])C(=C2O1)C([H])([H])[H])C([H])([H])[H]
[H]N([C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(=O)C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1C1=C(N([H])C(=O)C2=C(C([H])=C([H])S2)C([H])([H])[H])C(=NO1)C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=C([H])C(=C1C1=C([H])C([H])=C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C(=O)N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H][C@@]1(CCCCN1CC=C)[C@H](C(=O)OC)C1=CC=CC=C1
[H]OC1=C2C([H])=NC([H])=C([H])C2=NC(=C1C#N)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N([H])N=C1[H]
[H]O[C@@]1([H])[C@@]2([H])O[C@]([H])(C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC3=C([H])C(Cl)=C(C([H])=C23)C([H])([H])C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])C(=O)OC([H])([H])C1=C([H])[C@@]2([H])[C@@]3([H])O[C@@]4(O[C@@]3(C(=C([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]2(O4)[C@]2([H])C([H])=C(C(=O)[C@@]2(O[H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N2N=C([H])C(=C2[H])C(=O)N([H])C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C1=NC(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]C1=C(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(O1)C1=C([H])C([H])=C([H])C([H])=C1C(=O)C2=O
[H]C1=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C(C(=C1[H])C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C(=C([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])ON([H])C(=O)C1=C(N([H])C2=C([H])C([H])=C(I)C([H])=C2F)N(C(C(=O)C([H])([H])[H])=C1Cl)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(O[C@]([H])(C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C3=C(O2)C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C2N(C(=O)C([H])([H])[C@]2(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C1=O)[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C2=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=C(OC([H])([H])C4([H])C([H])([H])C4([H])[H])C([H])=C3[H])C(=C2N=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])[C@]([H])(N([H])S(=O)(=O)C2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1S(=O)(=O)N([H])C(=O)C([H])([H])[H])C1=C([H])C(=O)N(C([H])=C1[H])C([H])(F)F
[H]N1C(=O)C2=C3C(N([H])C4=C3C([H])=C([H])C([H])=C4[H])=C(C(=C2C1=O)C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N(C(=O)OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])N3O[C@@]4(C([H])([H])[C@@]3([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C1([H])[H]
Cc1cnc(Nc2nc(nc3ccccc23)N2CCCCC2)nc1-c1c[nH]c(c1)C(=O)NCc1ccccc1
[H]OC1=C2C(=O)\C(OC2=C(C(O[H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=NC(=N1)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=NC2=C(N=C([H])N=C2N([H])[H])N1[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C(Br)C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])N([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
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[H]OC([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N(C(=O)C([H])([H])C1=C2C([H])=C([H])SC2=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C1=NC([H])=NN2C([H])=C([H])C(=C12)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])N([H])C1(C2=C([H])C3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C(=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N1[C@@]2([H])C(C(=O)N(C([H])([H])[H])C([H])([H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])=C(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C4=C(OC([H])([H])[H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])[C@]1([H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])S1)C2([H])[H]
[H]N(N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(OC(=O)C1=NC3=C(C([H])=C([H])C([H])=C3[H])C([H])=C1[H])=C2[H]
[H]O[C@]([H])(C(\[H])=C(/[H])N1C(=C([H])C(=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C(Br)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)C([H])([H])[N+]3=C(C([H])=C(C([H])=C3C([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C2O[C@@]3([H])C(=O)\C(=C(/[H])C4=C5C([H])=C([H])C([H])=C([H])C5=C([H])C([H])=C4[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N/C(=O)C([H])([H])[H])\N([H])[H]
[H]OC(=O)[C@]([H])(C([H])([H])C([H])([H])N1C(=O)C2=C(C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C1=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(OC(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O)C(=S)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
CN1C=C(C=N1)C1=CC(F)=C(CN2C(=O)C3(CCN(C3)C3CCCC3)C3=C2C=CC=C3)C(F)=C1
[H]OC(=O)C1=C(C([H])=C(OC2=C([H])C(=C(N([H])C(=O)C3=C([H])C([H])=C([H])C(=C3[H])[N+]([O-])=O)C([H])=C2N([H])C(=O)C2=C([H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C([H])([H])[H])C([H])=C1[H])C(=O)O[H]
[H]C1=C(OC([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C(C(Cl)=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])N(C(=O)C2=C([H])C(=NC(=C2[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=S)N([H])C2=C([H])C(=C([H])C([H])=C2[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1=NC(=NO1)C1(C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N(C([H])([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1Cl)[C@@]1([H])C2=C(N(C(=O)C([H])=C2[H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N(C1=NN2C([H])=C([H])C([H])=C([H])C2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=NN(N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
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[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C2=C(N([H])C(=N2)C2=C([H])C([H])=C(Cl)S2)C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=NC([H])=C([H])S1
[H]N(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=C(OC([H])([H])[H])C([H])=C(C(=C1[H])C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@](O[H])(C([H])([H])N1C([H])=C([H])C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C(F)(F)F
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[H]N([H])S(=O)(=O)C1=C([H])C2=C(S1)S(=O)(=O)C([H])([H])C([H])([H])[C@]2([H])N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(OC3=C(C([H])=C([H])C(F)=C3[H])C([H])([H])[H])N(C3=C(N=C([H])C([H])=C23)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2O1)C1=NN=NN1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])S[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
[H]C1=C([H])N(C(=N1)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
FC1=C2C(C=CC=C2N2CCN(CCCCOC3=CC=C4CNC(=O)C4=C3Cl)CC2)=CC=C1
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C(N([H])C([H])([H])C1([H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C([N+]#N)=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N1N=C(N(C1=S)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=C1C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1F)C1=C([H])N(N=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N1C2=C(C(C(=O)OC([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(O[C@]3([H])N(C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C31)C([H])([H])[H])C([H])=C2[H]
[H]N(C(=O)C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])C1=C([H])C(=C(C([H])=C1[H])N1C(=O)C2=C(OC([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])N=C3C(OC([H])([H])C([H])([H])[H])=C2C1([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N(C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C#CC1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])N(N=C1[H])C([H])([H])C1=NOC(=N1)C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]C1=C(ON=C1C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])[C@]2([H])S[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N([H])C1=NC2=C([H])C([H])=C(C([H])=C2C(=N1)N([H])[H])C([H])([H])OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O\N=C(/N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C#C[C@@]2(N([H])C(=O)N([H])C2=O)C([H])([H])N2C(=O)C3=C(C([H])=C([H])C(OC([H])([H])[H])=C3[H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N([H])C1=NC([H])=NC2=C1N=C(SC1=NC3=C(S1)C(F)=C([H])C([H])=C3[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C(=C(C([H])=C2[H])C2=C3C([H])=C([H])C(C([H])=C3OC3=C([H])C(=C([H])C([H])=C23)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=[N+](C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])S([O-])(=O)=O)C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])C(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])OC1=C2N(C(=NC2=C(N=C1[H])C#CC(O[H])(C([H])([H])[H])C([H])([H])[H])C1=NON=C1N([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2OC(=C([H])C2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C(N(C([H])([H])[H])C([H])([H])C3=C([H])C([H])=NC([H])=C3[H])C3=C([H])C([H])=C([H])C1=C23
[H]OC1=C(C([H])=C2C([H])=C3C([H])=C([H])C([H])=C([H])C3=C([H])C2=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(N([H])C(=N[H])N([H])[H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C([H])=C1C1=C2C([H])=C(N([H])C2=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N(C2=NC([H])([H])C([H])([H])O2)C([H])([H])[H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]N(C(=O)C1(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\[H])C3=C([H])N(C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])[H])C2=C1[H]
[H]N1C(=O)N(C(=O)C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(\N=C(/[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=NC([H])=C1Cl
[H]N([H])C1=C([H])C(=C([H])C(=N1)C([H])([H])[C@]1([H])C([H])([H])N([H])C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C1=C(C([H])=C([H])N(N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C3=C1C([H])=C([H])C([H])=C3[H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]O[C@]1([H])[C@@]([H])(O[H])[C@@]([H])(O[C@]([H])(C([H])([H])N2N=C([H])N=C2[H])[C@@]1([H])O[H])C1=C([H])C(=C(Cl)C([H])=C1[H])C([H])([H])C1=NC([H])=C(S1)C1=C([H])C([H])=C([H])O1
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C#N
[H]OC(=O)C([H])([H])N1N=NC(=N1)C1=NN=C(S1)N1C([H])([H])[C@@]2([H])C([H])([H])N(C3=C([H])C(F)=C([H])C([H])=C3Cl)C([H])([H])[C@@]2([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1[C@]2([H])[C@@]3([H])C([H])([H])C([H])([H])[N@@+]4(C([H])([H])C5=C([H])C([H])=C([H])C([H])=C5[H])C([H])([H])C5=C([H])C([H])([H])O[C@@]([H])(N6C7=C([H])C([H])=C([H])C([H])=C7[C@@]78C([H])([H])C([H])([H])[N@@+]9(C([H])([H])C%10=C([H])C([H])=C([H])C([H])=C%10[H])C([H])([H])C%10=C([H])C([H])([H])O[C@]1([H])[C@@]([H])([C@]67[H])[C@@]%10([H])C([H])([H])[C@@]89[H])[C@]2([H])[C@@]5([H])C([H])([H])[C@@]34[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C2=C1N(C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N([H])[H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]OC(=O)C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC(Cl)=C1C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=NN([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(N=C1[H])C([H])([H])[H]
[H]N1[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]11C([H])([H])C([H])([H])C([H])([H])N([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=CC2=C(CN(C[C@]3(NC(=O)NC3=O)C#CC3=CC=C4C(=C3)C(C)OC3=CC=CN=C43)C2=O)C=C1
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C2C([H])=NN1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]ON(C(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])N([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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COC1=CC(=CC(=C1)C1=CC=NC=C1)C(C)C#CC1=C(N)N=C(N)N=C1C
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[H][C@@]1(CCCCN1CC1=CC=CC=C1)[C@H](C(=O)OC)C1=CC=CC=C1
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[H]N(C1=C([H])C(=O)N(C2=C1C([H])=NN2C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F
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[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N(C1=C([H])C(O[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])C(F)(F)F
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[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N(C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
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[H]N([H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N2[C@]([H])(C(=O)N([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C#N)C([H])([H])C([H])([H])[H]
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[H]N([H])S(=O)(=O)N([H])[C@]1([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)C(=C(I)I)C1=C([H])C([H])=C([H])C([H])=C21
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C12
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[H]N([H])C1=C([H])C(=NC(=N1)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(C1=C(C(=C([H])C(=C1[H])C1=NC(=NO1)C([H])([H])[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2C(Br)=NN3[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N=C(N([H])C([H])([H])C1=C([H])C([H])=C(I)C([H])=C1[H])N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C(=O)N([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(F)C(N([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[C@@]3([H])OC4=C(C([H])=C([H])C([H])=C4[H])N(C([H])([H])[H])C3([H])[H])C([H])=C2Cl)=C1[H]
[H]\C(=C(\[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C2=C(N(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(C(=O)OC2=C([H])C([H])=C(Cl)C([H])=C12)C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H]
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[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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FC1=CC=CC(OC2=CC=C(CN3C(=O)C(=O)C4=CC(OC(F)(F)F)=CC=C34)C=C2)=N1
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[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@]1([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(Cl)C([H])=C1C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)O[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])[C@@]3([H])N(C(=O)C([H])([H])[H])[C@@]([H])(C2([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N=[N+]=[N-])C(I)=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=S)N(C(=O)C1(C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])[C@]2([H])C([H])([H])[C@]2(C2=C([H])C([H])=C3OC([H])([H])C([H])([H])C3=C2[H])C1([H])[H]
[H]OC(=O)C1=C([H])C2=C([H])C(OC([H])([H])[H])=C([H])C(Cl)=C2O[C@@]1([H])C(F)(F)F
[H]OC([H])([H])C([H])([H])C([H])([H])N1C([H])=NC2=C1C([H])=C(C([H])=C2[H])C1=C2N(N=C1C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C([H])C(N([H])C(\N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(/[H])[N+]([O-])=O)=C1[H]
[H]C1=NC(=C(C([H])=C1[H])[C@@]([H])(C#N)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C([H])([H])S2(=O)=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(/C#N)C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@](N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC(=O)N2C([H])([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])=C([H])C(Cl)=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C([H])([H])F
[H]N(C([H])([H])C1=C([H])N=C([H])N=C1[H])C([H])([H])C1(N2C([H])([H])C([H])([H])N(C(=O)[C@@]3([H])C([H])([H])N(C([H])([H])[C@]3([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NN(C2=C1C([H])=C(N=N2)C1=C2C([H])=C([H])C([H])=C([H])N2N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)N1C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C2=C(C([H])=C(C([H])=C2C([H])([H])[H])C(=O)N([H])[H])C([H])([H])[H])C(SSC1(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1C([H])([H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(S[H])[C@]([H])([N+]([H])([H])[H])C([H])([H])C([H])([H])S([O-])(=O)=O)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)O[H]
[H]C1=C([H])C(=C([H])C([H])=C1O[C@@]1([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1([H])[H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C(F)(F)F)C([H])([H])C([H])([H])[C@]1([H])C2=C3OC(=NC3=C([H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C1=C(C2=NC3=C([H])C([H])=C([H])C([H])=C3S2)C(=C([H])S1)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
OC(=O)C(F)(F)F.NC(=N)C1=CC=C(CNC(=O)[C@@H]2CC3=CC=C(NC(=O)CN4CCN(CC4)CC(=O)NC4=CC(C[C@@H](NS(=O)(=O)CC5=CC=CC=C5)C(=O)N2)=CC=C4)C=C3)C=C1
[H]N=C(N([H])[H])C1=C([H])C2=C(O[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])N([H])[H])C([H])=C([H])C([H])=C2S1
[H]N(C(=O)N([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=NN(C([H])=C1C1=NC([H])([H])C2=C1C(OC1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=NC([H])=C2[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])N1C2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(N1C(=NN=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]C1=NC([H])=C(S1)C1=C2N(C(=N1)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C21
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)C1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])N(N=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])OC1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[C@@]2([H])O[C@@]([H])(C3=C([H])C(Cl)=C([H])C([H])=C3N3C([H])=C([H])C([H])=C23)C2=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=NC(=N2)C([H])([H])[H])N([H])C2=NC([H])=C(S2)C(=O)N([H])C2=C(Cl)C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(N=C(S2)N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N3C4=C5C(=C([H])C([H])=C([H])C5=C([H])C([H])=C4[H])S3(=O)=O)C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C([H])C(=N1)C1=C([H])N([H])C2=NC([H])=C([H])C([H])=C12
[H]N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])[C@@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(SC([H])([H])C([H])([H])[H])C([H])=C1[H])C2([H])[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])N=C(C2=C([H])C([H])=C([H])O2)C(=C1[H])C1=C([H])C([H])=C2C([H])=NC([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]O[C@]1(C([H])([H])N([H])C(=O)[C@@]2([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C2C(SC3=C([H])C4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])=C([H])N([H])C2=C([H])C([H])=C1[H])S(=O)(=O)C1=C(ON=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C(N=C1C1=C([H])C([H])=C(N=C1[H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@]1([H])C([H])([H])C([H])([H])[N@@]2C([H])([H])\C(=N/OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C2([H])[H]
[H]N([H])C(=O)C([H])([H])SC([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=C2C(=NC([H])=N1)N=C(C1=C([H])C([H])=C([H])S1)C(C1=C([H])C([H])=C([H])C([H])=C1[H])=C2C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C([H])C2=C(N=C([H])N=C12)N(C([H])([H])[H])[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C1=C2C([H])=C([H])C([H])=C1[H])=C1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(I)C(=O)C([H])([H])[C@@]2([H])N1C([H])([H])C([H])([H])C2([H])[H]
[H]\C(=C(\[H])C([H])([H])N(C(=O)C([H])([H])Cl)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1C1=C(C([H])=C(C([H])=C1[H])C([H])([H])N=[N+]=[N-])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C(=O)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@@]([H])(N([H])C(=O)C(OC1=C([H])C([H])=C(C([H])=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]N=C(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
OC1CN(C1)C(=O)C1=C(NC2=CC=C(I)C=C2F)C2=C(NN=C2)C=C1
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[H]C1=C([H])C(F)=C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C([H])([H])SC([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=CC=C(C=C1)C1=NN2C(=C1)C1=C(NC2=O)C=CC=C1
[H]\C(=C(\[H])C1=C([H])C([H])=C(F)C([H])=C1F)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
OB(O)[C@@H]1CCCN1C(=O)CNC(=O)C1=CC(Cl)=CC=C1Cl
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC(=NC(=N1)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC2=C([H])C([H])=C(C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1OC1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
[H]\C(N1N=C([H])N=C1[H])=C(\OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC(=O)[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2O[H])C([H])([H])[C@@](N([H])[H])(C(=O)O[H])C1([H])[H]
[H]N([H])C1=NC(N(C(=N1)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C2C(SC3=C2N=C([H])N(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C3=O)=N1)[N+]([O-])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])N(N([H])C1=NC([H])([H])C([H])([H])N1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)C2(C3=C([H])C(=C([H])C(F)=C13)C1=C([H])C([H])=C(C#N)N1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=NC2=C(S1)C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1=C(N([H])C(=O)C2=C([H])C3=C(N2[H])C([H])=C([H])C(Cl)=C3[H])C([H])=C([H])C(=C1[H])C(C(=O)OC([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(C([H])=NN1C1=C([H])C([H])=C([H])C([H])=C1F)C(=O)N([H])C1=C(C([H])=C([H])C(=C1[H])C(=O)N([H])C1=C([H])C([H])=NN1C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@]2([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C(=O)[C@@]1([H])[C@]2([H])C([H])=C([H])[C@@]([H])(C2([H])[H])[C@@]1([H])N([H])C1=C(Cl)C([H])=NC(=N1)N([H])C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N1C(=C([H])C([H])=C1C([H])([H])N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C(Br)=C1[H]
COC1=C(OC)C=C(CC(OC(=O)\C=C\C2=CC3=CC=CC=C3C=C2)C(=O)NO)C=C1
CC(C)CNc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(Cl)c1
[H]N([H])[C@]1([H])C(=O)C([H])([H])C2=C(C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C2C(=N1)N(C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C1=NC(=C([H])S1)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])[C@]2([H])C([H])([H])N(C(=O)C3=C([H])C([H])=NC([H])=C3[H])C([H])([H])[C@]12[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C2=C1N([H])C(=O)C([H])([H])C2([H])[H]
[H]N(C(=O)C1=NC2=C(S1)C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])[C@]1([H])C([H])([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C1=C([H])C(=O)C2=C(N1[H])C([H])=C([H])C(Cl)=C2[H]
[H]OC1=C([H])C(O[H])=C2C(=O)C([H])=C(OC2=C1C(C([H])=C([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C(C([H])=C(C([H])=C1[H])[N+]([O-])=O)S(=O)(=O)N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(N=C([H])N2C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])[C@]2([H])N(C(=O)C3([H])C([H])([H])C3([H])[H])C(=O)[C@@]([H])(C([H])([H])[H])[C@@]12[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])[C@]([H])(O[C@@]([H])(C([H])([H])O[P@](=O)(O[H])C([H])([H])[P@](=O)(O[H])OC([H])([H])[C@@]2([H])O[C@]([H])(C3=NC(=C([H])S3)C(=O)N([H])[H])[C@]([H])(O[H])[C@]2([H])O[H])[C@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])[H]
[H]ON([H])C(=O)[C@@](O[H])(C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])[C@]([H])(C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C(=NC(=C1F)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])(F)F
[H]N(C(=O)C1=NN(C2=C([H])C([H])=C([H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C3([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])SC2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])OC3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)=C(C([H])=C12)C([H])([H])[H]
[H]N1C(=O)S\C(=C(\[H])C2=C(OC([H])([H])C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C([H])=C([H])C(Br)=C2[H])C1=O
COC1=CC2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=CC=C(C=C3)C(=O)N3CCN(CC3)C3CCCCC3)C2=O)C=C1
[H]OC([H])([H])C1=C(N=C(C(C([H])=C([H])[H])=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])=C(C(=NC1=O)N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[P@](=O)(O[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])[H]
[H]C1=C([H])C(OC(=O)C([H])([H])[H])=C(C([H])=C1[H])[C@@]1([H])OC(=NN1C(=O)C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]N1C([H])=C([H])C2=C(N=C([H])N=C12)N(C([H])([H])[H])[C@@]1([H])C([H])([H])N(C(=O)[C@@]2([H])C([H])([H])C(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])N1N=C(C2=C1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C2([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C(SC3=C([H])C(F)=C([H])C([H])=C23)C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=S)N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC2=C(N1[H])C([H])=C(Cl)C([H])=C2OC([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=NC(N([H])C3=C([H])C(=C([H])C([H])=C3S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C3=C(C([H])=C(OC([H])([H])[H])C1=C3[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])=C(Cl)C([H])=N2
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[H]C1=NC2=C(SC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)N=C([H])N=C2N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N=C([H])N=C2N1[H])N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C([H])=O)[C@]([H])(C(=O)O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])OC(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C3=C1OC1([H])C33C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])(C2([H])[H])C32C([H])=C([H])C1(OC([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])(C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@@](C([H])([H])[H])(C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C([H])C([H])=C3[H])C(=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C(C([H])=C(C2=N1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C#N
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[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NN(C2=NC(SC([H])([H])[H])=NC(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C12)C([H])([H])[C@]([H])(Br)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC(=NC(=N1)N([H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])O1)C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C2=C(C#N)C3=NN=C(N3C([H])=C2[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])C([H])([H])F)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@](C(=O)N4C([H])([H])C([H])([H])N(C([H])([H])C5=C([H])C(OC([H])([H])[H])=C([H])C([H])=C5[H])C([H])([H])C4([H])[H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)OC([H])([H])[H]
[H]OC1=NC2=C([H])C([H])=C(C([H])=C2N1C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(C#N)=C([H])C(F)=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CN1C(=N)N[C@]2(CN(C[C@H]2C1=O)C1=NC(C)=C(F)C(=N1)C1CC1)C1=CC=CC=C1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C(O[H])C([H])=C2C1=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N(C(=O)N(C1=O)C([H])([H])[C@]([H])(N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1F)C(F)(F)F
[H]N(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])N([H])C1([H])C([H])([H])C1([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C2=C3N(C([H])=C2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])S(=O)(=O)N(C3=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C(=O)[C@]1([H])SC2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[N@+](C([H])([H])[H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=NC2=C(N1[H])C(=C([H])C([H])=C2[H])C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])SC1=NC2=C([H])C([H])=C(N([H])C([H])([H])C(\[H])=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C(=O)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=C(C=C(N1C1=CC=C(C=C1)S(N)(=O)=O)C1=CC2=CC=CC=C2C=C1)C(=O)NCCN1CCCC1
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C([H])C([H])=C([H])C([H])=C3S2(=O)=O)C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])O[C@]2(O[C@](C(=O)O[H])([C@]([H])(OC(=O)C(\[H])=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@@]2([H])O[H])[C@]1(O[H])C(=O)O[H])C([H])([H])C([H])([H])C(=C([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
Cc1cnc(NC2CC2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(F)c1
[H]N([H])C1=C([H])C(=C([H])C(=N1)C([H])([H])[C@@]1([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N([H])C(=O)C([H])([H])C([H])([H])SSC([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])C(=O)OC21C2=C([H])C([H])=C(O[H])C([H])=C2OC2=C1C([H])=C([H])C(O[H])=C2[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])[C@]([H])(OC(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(F)=C([H])C(F)=C1[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]N([H])N1C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[C@@]11N([H])C(=O)N([H])C1=O
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[H]N([H])C1=NC(N([H])[H])=C2C(=N1)N([H])C(SC1=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C1[H])=C2C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N1C2=C(OC([H])([H])C1([H])[H])C([H])=NC1=C2C2=C(S1)C(=O)N(C([H])=N2)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C#CC([H])([H])N([H])C1=NC([H])=NC2=C1C1=C(S2)C(=O)N(C([H])=N1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(S2)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C(C([H])=C([H])S1)C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C1=NC(=C([H])N1[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
C=CC(=O)NC1=CC=C(C=C1)S(=O)(=O)N1CCN(CC1)C(=O)OCC1=CC=CC(OC2=CC=CC=C2)=C1
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NOC3=C2C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]C1=C([H])[C@]2([H])C([H])([H])[C@@]1([H])[C@@]1([H])C(=O)N(C(=O)[C@@]21[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=NN2C([H])=C([H])C(=C12)C([H])([H])OC([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])N([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1N=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(SC2=C([H])C3=C(OC([H])([H])O3)C([H])=C2Br)=NC2=C1N=C([H])N=C2N([H])[H]
[H]N([H])C1=C(N([H])C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])O1)C1=NC2=C([H])C([H])=C([H])C([H])=C2S1
[H]N(C(=O)C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C([H])C3=C([H])N=C(C([H])=C23)C2=C([H])N=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C2[H])C2=C1C([H])([H])C([H])([H])C([H])([H])N([H])C2=O
[H]N(C1=C([H])C(F)=C([H])C([H])=C1[H])C1=C(C([H])=NC([H])=C1C#N)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(C1=NC([H])=C(C([H])=C1[H])N(C(=S)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C#N)C([H])([H])[C@]1([H])C([H])([H])OC([H])([H])C1([H])[H])(C(F)(F)F)C(F)(F)F
[H]N([H])C1=C(C([H])=C(Cl)C2=NON=C12)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C1([H])[H])[C@]1([H])C2=NC([H])=C(Br)C([H])=C2C([H])([H])C([H])([H])C2=C1C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1=C([H])[N+]([O-])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1N=C2C(=N1)C(Br)=C(Br)C(Br)=C2Br
[H]N([H])C(=O)C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])C([H])=C(OC2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C2=C(C([H])=C1[H])C(=C([H])C1=C(C([H])=C([H])C([H])=C1[H])C2=O)C1=NN([H])N=N1)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])C2=C(C#N)C(=O)N(C([H])=C2[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C(=N1)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2F)C2=C([H])C([H])=C([H])C([H])=C2N([H])C1=O
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C1=C(O[H])C2=C(C([H])=C([H])C(=C2[H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])N(C1=O)C([H])([H])[H]
CCCN(CCCCOC1=CC=C(CC2=CC(=CC=C2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C=C1)C(=O)CCC1=[N+]2C(C=C1)=CC1=C(C)C=C(C)N1[B-]2(F)F
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C(N(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(C#N)=C([H])C(=C2O1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2[H])C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]2([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C3=C([H])N([H])C4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])C(=O)N([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]3([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C3([H])[H])C(=O)N([H])[H])N([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC1=C([H])C([H])=C2C3=C1O[C@]1([H])[C@]33C([H])([H])C([H])([H])N(C([H])([H])C4([H])C([H])([H])C4([H])[H])[C@]([H])(C2([H])[H])[C@@]32N(C([H])([H])[H])C([H])([H])[C@]1(O[H])C([H])([H])C2([H])[H]
[H]OC([H])([H])C([H])([H])N(C([H])([H])C1=NC(=NS1)C1=C([H])N(C2=C(Cl)C([H])=C([H])C([H])=C12)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(O[H])C1(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(N([H])[H])C(=O)N1[C@@]2([H])C([H])([H])[C@@]2([H])C([H])([H])[C@@]1([H])C#N
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C3=C(C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])C([H])([H])C2=O)C([H])([H])C1([H])[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\C(=O)OC([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])N3[H])C2=C1[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C3=NC([H])=C([H])C(OC([H])([H])[H])=N3)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(S1)C([H])([H])C([H])([H])C(=O)N([H])C1=NC([H])([H])C([H])([H])C([H])([H])N1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])[H])C([H])([H])C1([H])[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=[N+]([O-])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=C(C([H])=C(OC1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
CN1C=CC2=C1C(OC1=CC=C(NC(=O)NC3=CC=CC(F)=C3)C=C1)=NC=N2
[H]N=C(N([H])[H])N([H])N=C([H])C1=C(N=C2SC(F)=C([H])N12)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)C([H])([H])C(=O)N1C([H])([H])C([H])([H])[C@]2(SC([H])([H])C([H])([H])S2)C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(O2)C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=NC(=O)C1=C(N([H])[H])C([H])=C(O1)C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])N([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N2C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C(N([H])C2=NC([H])=NC(N([H])C3=C(F)C([H])=C([H])C([H])=C3F)=C2[H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1(C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])N(C([H])=N1)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N([H])C1=C(Cl)C([H])=C(C([H])=C1Cl)C(=O)N1C([H])([H])C([H])([H])[C@@]([H])(N2C(=O)OC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C([H])([H])N(C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(C#N)=C(\[H])[C@@]1(C([H])([H])[H])[C@@]([H])(N2C(=O)C([H])([H])[C@@]2([H])S1(=O)=O)C([O-])=O
[H]C1=NN(C([H])=C1C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
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[H]N([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(C([H])=NN1C1=C([H])C([H])=C([H])C([H])=C1F)C(=O)N([H])C1=C(C([H])=C([H])C(=C1[H])C(=O)N([H])C1=NOC([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC(=N1)C([H])([H])[H])C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C#N)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1F
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C(OC(F)(F)F)C([H])=C([H])C(N([H])C(=O)C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(OC(=O)N(C2=C([H])C(=C([H])C([H])=C2[H])C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]12O[C@@](O[C@]([H])(C([H])([H])O[H])[C@@]1(O[H])C(=O)OC([H])([H])[H])(C([H])([H])C([H])([H])C(=C([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(O[H])[C@@]2([H])OC(=O)C(\[H])=C(/[H])[C@@]([H])(C([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C(O[H])=C1[H]
[H]N(C(=O)C1=C(C([H])=C([H])S1)S(=O)(=O)N([H])C1=C(Cl)C(=NO1)C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C(=O)N([H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C(=O)C1=C(N(N=C1[H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(C([H])=C1[H])C([H])=C(Cl)C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])[C@@]3([H])N(C(=O)C([H])([H])[H])[C@@]([H])(C2([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(C([H])=NC2=C(Br)C([H])=NN12)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])C([H])([H])[C@@](O[H])(C4=C([H])C([H])=C([H])C([H])=C4[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
[H]N([H])C1=C([H])C([H])=C(OC2=C(OC(=C([H])C2=O)C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@]1([H])C([H])([H])N(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(C([H])=C(S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C(=O)N([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])[H])C([H])([H])C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])=C([H])C([H])=C2OC([H])([H])[H])=N1
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)[C@@]1([H])[C@]2([H])C([H])([H])N(C3=NC([H])=C([H])S3)C([H])([H])[C@]12[H]
CN1C(N)=N[C@](C1=O)(C1=CC=C(OC(F)F)C=C1)C1=CC(OCCCF)=C(F)C=C1
FC(F)(F)C1=CC=CC=C1C(=O)N1CCN(CC1)C1=NN=C(C=C1)C(=O)NCC1=NNC=C1
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)[C@@]1([H])N([H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=CC2=C(N1)C=CC(NC(=O)\C=C\C1=CC=CC(Cl)=C1)=C2
[3H]C1=CC(=CC=C1Cl)C1=C(C2=NN(CC3=CC=C(N=C3[3H])C(F)(F)F)C(=O)N2N=C1)C1=CC=NC=C1
[H]ON([H])C(=O)C([H])([H])[C@]1(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])C3=C4C([H])=C([H])C([H])=C([H])C4=NC(=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C1N([H])C(=C([H])C(C2=C([H])C([H])=C(O2)C([H])([H])[H])=C1C#N)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C(=O)C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]2(C([H])=C([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(N([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1C(=O)C1=C(F)C([H])=C([H])C([H])=C1F
[H]N(C1=C([H])C2=C(C([H])=C1[H])C([H])=C([H])C1=C(C([H])=C(C([H])=N1)C1=C([H])N(N=C1[H])C([H])([H])[H])C2=O)S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1N=C(C2=C1C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C1(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C(F)(F)F
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(=C([H])C([H])=C2O1)C(=N[H])N([H])[H]
[H]C1=NN=C(N1C([H])([H])[H])[C@]([H])(N(C1=C([H])C(Cl)=C(C#N)C([H])=C1[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
[H]N1C(=O)N([H])C2=C(C1=O)C(=C([H])C(=O)O2)C([H])([H])C([H])([H])C([H])([H])C1(Cl)C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])[H])[C@]1(O[H])C([H])([H])[H])N1C([H])=NC2=C1N=C(N=C2N([H])C([H])([H])C1=C([H])C(I)=C([H])C([H])=C1[H])N([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C2=C(N([H])N=C2C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1F
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])[C@]1(C2=C(Br)C(=O)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C(F)(F)F
[H]C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])C#CC([H])([H])N1C([H])=NC([H])=C1[H]
[H]S\C(=N/N(N([H])[H])C1=C(F)C(F)=C(F)C(F)=C1F)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N(C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])C(Cl)=C3[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(C#CC([H])([H])N([H])C(=O)C([H])([H])OC([H])([H])[H])C([H])=C12
[H]N(C1=C2N=C([H])N(\C([H])=C(/[H])C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C2=NC(OC([H])(C([H])([H])[H])C([H])([H])[H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])P(=O)(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=O)OC2=C(F)C([H])=C1C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C2=C([H])C3=C(N=C(N=C3N=C2C([H])([H])C1([H])[H])N([H])[H])N([H])[H])C(=O)O[H]
[H]N=C(OC([H])([H])[H])N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2C([H])=C1N([H])C1=C(Cl)C([H])=NC(=N1)N([H])C1=C([H])C(=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H]
COCCCC1=NC=C(Cl)C(CN(C2CC2)C(=O)[C@H]2CNCC[C@@H]2C2=CN=C(OCCOC3=C(Cl)C=C(C)C=C3Cl)C=C2)=C1
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)C1(C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(/C#N)C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=NC2=NC(=C([H])N12)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C2C(OC3=C2C([H])=C(C([H])=C3[H])C2=NOC(=N2)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C2C([H])=C(C(=O)N(C2=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=NC([H])=C([H])O2)C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C1=C(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])C([H])([H])C3=C12)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1N=C(C([H])=C1C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
COC1=C(OC)C=C(CCOC(=O)C2=C(CN(C)CC2)C2=CC=CC=C2)C=C1
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[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(O[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
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COC(=O)C1=CC2=C(NCC1)N=CN=C2NC1=CC(Cl)=C(OC2=CC=CC(=C2)C(F)(F)F)C=C1
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[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C(=O)[C@]([H])(N([H])C(=O)[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])N2N1C(=O)N(C2=O)C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
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COC1=CC(=CC=C1OCCN1CCCC1)N1CC2=CC=C(CC3=C(C)C=CC=C3)N=C2C1=O
[H]N(C1=NC(=NN1C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C1=C([H])C(=NC(=N1)C(F)(F)F)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C(Br)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C(OC(F)(F)F)C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])[N+]([O-])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
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[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=N2)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C([H])=C([H])C(Cl)=N1)N1C([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N1[C@]([H])(SC([H])([H])[C@@]1([H])C(=O)C1=C([H])N(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C1C([H])=C([H])C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C2[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])N(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]1([H])N2C(=O)[C@@]([H])(N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C4=C3N([H])C([H])([H])[C@]([H])(C([H])([H])[H])C4([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C(C([H])=C([H])C([H])=C1[H])[N+]([O-])=O
[H]C#CC([H])([H])N1C(=O)C2=C(SC3=C2C([H])([H])C([H])([H])C3([H])[H])N=C1C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)O[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)[C@@]([H])(N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C#N)C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C(N([H])C(=O)C([H])=C2[H])C1=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
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[H]N1C(=O)N([H])[C@]([H])(C1=O)C1=C([H])C(Cl)=C([H])C([H])=C1S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1N([C@]([H])(C([H])([H])[H])C([H])([H])OC(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N=C([H])N=C2N1[H])N([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
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[H]N(OC([H])([H])[H])C(=O)N([H])C1=C([H])SC(=N1)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N(N([H])C1=C2C(=NC3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C(Cl)=C1[H])C([H])([H])[H]
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[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C3C(=NC([H])=C2[H])N([H])C([H])=C13
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[H]O[C@@]([H])(C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C#N)C(=N\C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])\N1C([H])([H])C([H])([H])C(=C2C3=C(C([H])=C(Br)C([H])=N3)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1\N=N\C1=C2C([H])=C([H])C([H])=C([H])C2=C(C([H])=C1O[H])S(=O)(=O)O[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(OC([H])([H])[H])C(Cl)=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(S1)C1=NSC2=C1N=C([H])N=C2SC([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C(OC([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])=C1[H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
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[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])S(=O)(=O)C([H])([H])[C@]([H])(N([H])C1=O)C(=O)O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)C1=NC2=C(O1)C([H])=C([H])C(=C2[H])C(=O)OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C1=NN=C(O1)C([H])([H])[H])C1=C([H])C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=N1)C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
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[H]N([C@@]1([H])C(=O)N(C2=C([H])C([H])=C(C([H])=C2F)C2=NC([H])=C([H])N2C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C(Cl)C([H])=C2C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)C([H])([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H])C1=NC(Cl)=NC2=C1N=C([H])N2C([H])([H])[H]
[H]N1C(=O)C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=C([H])N=C4C([H])=C([H])C([H])=C([H])C4=N3)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NN([H])C2=C1C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C(=O)N([H])C1([H])C([H])([H])N(C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C2([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)OC([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
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[H]O[C@@]12C([H])([H])C([H])([H])[C@]3([H])[C@@]([H])(C([H])([H])[H])[C@@]4([H])N(C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C4([H])[H])C([H])([H])[C@@]3([H])[C@]1([H])C([H])([H])[C@@]1([H])[C@@]2([H])C([H])([H])C(=O)[C@@]2([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
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[H]N(C([H])([H])C([H])([H])C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N(C1=C([H])C([H])=C([H])C(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])[H]
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[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=NC([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
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[H]C1=C([H])C2=C(C([H])=C1[H])C(SC1=C([H])C([H])=C(F)C([H])=C1[H])=C(C(=O)C2=O)C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C([H])([H])[C@]([H])(C(=O)N([H])C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C(C2=NSN=C2SC([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C(\C([H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(C3=C([H])C([H])=NC([H])=C3[H])=C(C([H])=C12)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C(Cl)=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C1=C2N=C([H])C([H])=C(C2=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=C(C(=O)OC([H])([H])C([H])([H])[H])C(C(=O)C([H])([H])OC(=O)C(\[H])=C(/[H])C2=C([H])C(F)=C([H])C([H])=C2[H])=C1C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C(S1)C1=C([H])C2=C(C([H])=C1[H])N1C(=C(C(=O)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
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[H]N=C(N([H])C1=C(\C([H])=C(/[H])C2=C(F)C(F)=C(F)C(F)=C2F)C([H])=C([H])C([H])=C1[H])N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
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[H]N([H])C(=O)C1=C(C(=C(N1[H])C([H])([H])[H])C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(N=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C(S1)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C(N([H])C2=NC(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])=NC([H])=C2[H])=C1[H])C([H])([H])[H]
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[H]O[C@](C1=C([H])C2=C([H])C(C#N)=C(C([H])=C2N1[H])C(F)(F)F)(C([H])([H])[H])C([H])([H])SC1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])S1
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[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C1([H])[H])S2(=O)=O
[H]OC(=O)C(=O)N(C1=C([H])C([H])=C2N(C([H])([H])[H])C([H])([H])[C@](OC2=C1[H])(C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
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[H]N=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NC2=C([H])C([H])=C3N=C([H])N(C(=O)C3=C2S1)C([H])([H])C([H])([H])[H]
[H]N(C1=C(N(N(C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(=O)OC([H])([H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])C2=C(C3=C([H])C(F)=C([H])C(=C3N2[C@]([H])(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2=O)C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1Cl)C(=O)C([H])([H])SC1=NC(=C([H])C(=O)N1[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C2N(C(=O)[C@]([H])(C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=S)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C(=O)N1C2=C(N([H])C3=C(C([H])=NN3C([H])([H])[H])C1([H])[H])C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C(SC([H])([H])[H])=C2C(=C1[H])[C@@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C3OC([H])([H])OC3=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1C1=C(N([H])C(=O)C2=C3N=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C(=NO1)C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])=C([H])C([H])=C1C2=O
FC1=CC=CC(=C1)C(C1=CC=NC=C1)C1=CC2=C3N(CCC3=C1)C(=O)CC2
[H]N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H]
[H]N1C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])N(C3=C([H])N=C(Cl)C(=C3[H])C([H])([H])[H])[C@@]2([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])[C@]([H])(C(=O)N([H])[C@@]([H])(C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C(F)C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=C(C2=C(N=C([H])N=C12)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
CC1=C(C=CC=C1Cl)C(=O)N1CCC[C@@H](C1)C1=NN=C(O1)C1=CC=CC=C1
[H]N([H])C1=NC2=C(N=C(C([H])=C2[H])C([H])([H])N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)N([H])[H]
[H]N(C1=C([H])C([H])=C(N=N1)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C(\C([H])=C(/[H])C(=O)C2=C(O[H])C([H])=C(O[H])C([H])=C2OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC([H])=NC(=C1[H])N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])N([H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C(SC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O\C(=C(\C#N)C(=O)N([H])C1=C([H])C(Cl)=C(C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
CN1N=NN=C1C1=CC(NC(=O)N(CCC(C2=CC=CC=C2)C2=CC=CC=C2)CCN2CCOCC2)=CC=C1
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(N([H])C(=O)C2=C(O[H])C3=C([H])C([H])=C([H])C([H])=C3N=C2O[H])C([H])=C1[H]