[H]OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=C(N=C([H])C([H])=N2)C([H])([H])C2([H])C([H])([H])N(C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=N3)C2([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])S(=O)(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]C1=C([H])C([H])=C(O1)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])S1)[C@]([H])(C1=NN=NN1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)OC1=C([H])C([H])=C2C(=C1[H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])[C@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(SSC1([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])[C@@]1(OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])S(=O)(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1(C([H])([H])C2=C([H])C(=C(C([H])=C2[H])N2C(=O)C3=C(OC([H])([H])C([H])([H])[H])C4=C([H])C([H])=C([H])C([H])=C4C(OC([H])([H])C([H])([H])[H])=C3C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])N([H])C([H])([H])C([H])([H])N([H])C1([H])[H])[C@@]([H])(C1=NN=C(N1C([H])([H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])C1=C([H])C([H])=C([H])C(SC2=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(=C2C(F)(F)F)C(F)(F)F)=C1[H]
[H]N(C(=O)N([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C(N([H])C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])N=C(Cl)C([H])=C1[H]
[H]N([H])C(=O)C1=NC([H])=C([H])C2=C1N([H])C1=C2C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=NC([H])=C([H])S1
[H]N(C(=O)C([H])([H])C([H])([H])OC1=C2C([H])=[N+]3C(=C([H])C2=C([H])C([H])=C1OC([H])([H])[H])C1=C(C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(C([H])=C2[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C(O2)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]O[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])OC1=NC([H])=C(C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F
[H]N(C1=NN2C(=NC(=C2C([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C(Br)=C1[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)[C@]([H])(N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=NC([H])=C(Cl)C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=C(\[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H])\C(F)(F)F
[H]N1C2=C(C([H])=C([H])C(=C2[H])C2=N[N+]3=C(N=N[C@]3([H])C([H])([H])C3=C([H])C4=C([H])C([H])=C([H])N=C4C([H])=C3[H])C([H])=C2[H])C2(C1=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC(=O)C(=O)[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C(N([H])[H])C([H])=C2C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(OC(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C2C(=C1[H])C1=C(SC(=N1)[N+]([H])([H])[H])C2([H])[H]
[H]C1=C([H])N2C(Br)=C(N=C2C(OC([H])([H])C2=C(Cl)C([H])=C([H])C(N(C(=O)C([H])([H])OC([H])([H])[H])C([H])([H])[H])=C2Cl)=C1[H])C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])C4=C(C5=C(N4[H])C([H])=C([H])C(I)=C5[H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C(=O)C1=NC(N2C([H])([H])C([H])([H])C(F)(F)C([H])([H])C2([H])[H])=C2C([H])=NC([H])=C([H])N12)[C@]([H])(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])N(C(=O)C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C2[H])C([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(SC1=NN=C(N1C([H])([H])[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C([H])=C([H])C3=C([H])C([H])=C(N=C23)C2=NN=C3C([H])=C([H])C(=C([H])N23)C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(F)C1([H])[H]
[H]OC(=O)[C@]([H])(C1=C([H])C([H])=C(O[C@]2([H])C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])=C1F)C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C(=O)C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)N([H])C([H])([H])C1(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N1C2=C([H])C([H])=C(I)C([H])=C2C(=O)N([C@]([H])(C(=O)O[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1=O
[H]N(C(=O)[C@@]([H])(N1C(=O)[C@@]([H])(N2C(=O)OC([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N1C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1=O)C1=C2N=C(C([H])=NC2=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=NN1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])N([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
Cl.C(N1CCC2(CCCC3=CC=CC=C23)CC1)C1=CC=CS1
[H]N(C(=O)N([H])[C@@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]OC1=C2C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C([H])C2=NC(=C1[H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C2=NN=C3N2C2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])OC3([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])C2(OC([H])([H])C([H])([H])O2)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)C(=C1[H])C([H])([H])N1N=C([H])N=C1[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C(=O)C1=C([H])C([H])=C2SC3=C([H])C([H])=C([H])C([H])=C3C(=C([H])N12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC2=C1C([H])=C(N2[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C(=O)N(C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(SC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NN(C(OC([H])([H])C(=O)C2=C([H])C([H])=C(Br)C([H])=C2[H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(SC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(OC([H])([H])C([H])([H])[H])C(=O)C1=C([H])N(C(=O)C(=C1N([H])C1=C([H])C([H])=C(Br)C([H])=C1F)C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])N1N=C(C2=C1C([H])([H])C([H])([H])N([H])C2([H])[H])C1=C([H])C(SC([H])([H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(S1)C1=NC(=NC([H])=C1[H])N([H])C([H])([H])[H]
[H]OC(=O)C(=C(/[H])C1=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])=C2S1)\C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])N(N=N1)C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])N=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C3OC([H])=C([H])C3=C12
[H]N1N=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C1C(=O)N(C2=O)C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC([H])([H])[C@]1([H])O[C@@]([H])(N2C([H])=C(C(=O)N([H])[H])C3=C(N=C([H])N=C23)N([H])[H])[C@]([H])(O[H])[C@@]1([H])O[H]
[H]N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
CC[Si](CC)(C1=CC=C(OC[C@H](O)CO)C(C)=C1)C1=CC=C(OC[C@H](O)C(C)(C)C)C(C)=C1
[H]OC1=C(N([H])C2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H]
CC1=CC(O)=CC(C)=C1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](C(=C)C(O)=O)C1=CC=CO1
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1S(=O)(=O)N([H])C(=O)C([H])([H])[H])C1=C([H])C(=O)N(C([H])=C1[H])C([H])(F)F
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])S1)C1=NC2=C(S1)C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=NN=C(N2C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C(=O)C2=C(Cl)C([H])=C(F)C([H])=C2[H])C(OC([H])([H])[H])=C1[H]
[H]N1C([H])([H])C(=O)N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])[C@@]([H])(C([H])([H])OC([H])([H])C2=C(F)C(=C([H])C([H])=C2[H])C(F)(F)F)C1([H])[H]
[H]OC(=O)C([H])([H])O\N=C(/[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC(=C(S1)C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])=C([H])C2=C1C(Cl)=C([H])C([H])=C2[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(OC([H])([H])[H])C(=O)N(C([H])([H])C1=C([H])SC([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C(N=C(C([H])=C1C([H])([H])[H])C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])[C@]([H])(N([H])C(=O)C4=C([H])C([H])=NC([H])=C4Br)C([H])([H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]N1C([H])([H])C([H])([H])O[C@]([H])(C1([H])[H])[C@]([H])(OC1=C(C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])[C@]1([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2OC(=O)C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(S1)C1=NC(=NC([H])=C1[H])N([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]O[C@]1([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C1=NC([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N1C2=C(C3=C1C([H])([H])C1(N([H])C3=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C2C([H])=C(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)C([H])([H])[C@]1([H])N(C(=NC2=C([H])C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C2=C(C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C2C([H])=C3C([H])=C([H])C([H])=C([H])C3=C([H])C2=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(N=C(N([H])[H])N([H])[H])N=C1[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2[C@]([H])(C1=O)C([H])([H])C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F
[H]C1=C(N2N=C(N(C(=O)C2=C1[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C2=NC([H])=C(C(=N2)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C(C([H])=NC3=C([H])C(=NN23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1=O
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O
[H]N(C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C(=O)C1=C(O[C@@]([H])(C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])=C(S1)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])N12
[H]C1=C([H])C2=C(O[C@]([H])(C([H])([H])N3C([H])([H])C([H])([H])N(C4=C(Cl)C([H])=NN(C4=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])N(C5=C([H])C([H])=C([H])C([H])=C5OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C([H])([H])O2)C([H])=C1[H]
[H]N([H])C1=N[C@@](C(=O)N1C([H])([H])[H])(C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=C([H])N=C1[H])C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC([H])([H])[C@@]([H])(O[H])C1(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(N([H])[H])C(=O)N1[C@@]2([H])C([H])([H])[C@@]2([H])C([H])([H])[C@@]1([H])C#N
[H]N1N(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C(=O)\C(=C(/[H])C2=C([H])C([H])=C([H])C(OC([H])([H])C3=C([H])C(=C([H])C([H])=C3[H])C([H])([H])[H])=C2[H])C1=O
[H]O[C@@]([H])(C1=C(F)C(F)=C(F)C(F)=C1F)C([H])([H])N([H])C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@@]([H])([C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N1C(=S)N([H])C(C1=O)(C1=C([H])C([H])=C(I)C([H])=C1[H])C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]N([H])N([H])C(=O)C1=C([H])C2=C(S1)C([H])=NC([H])=C2SC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=C1C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(Br)C([H])=C(Br)C(=O)C(Br)=C1[H]
[H]N(C(=O)C1=C([H])C(\C([H])=C(/[H])C2=C([H])N=C3C([H])=C([H])C([H])=NN23)=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(C(=O)C([H])([H])N([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]O[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=NC(=C([H])O1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(O[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])[C@]([H])(C([H])([H])OC1=C([H])C([H])=C3OC([H])([H])OC3=C1[H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]OC([H])([H])C1=NN(C([H])=N1)C1=C([H])N2C(=NC(=C2C([H])([H])[H])C([H])([H])[H])C(N([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N1C([H])=C([H])C([H])=C1C1=C(OC([H])([H])C2=NC([H])([H])C([H])([H])N2[H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])N([H])C2=C([H])C([H])=C([H])C([H])=C2C#N)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N=C(Cl)S1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
CN1C=C(C=N1)C1=CC=C(CN2C(=O)C(O)(C3=CC=CC=C23)C(F)(F)F)C=C1
[H]OC(=O)C1=C(O[H])C([H])=C2OC(=C(C3=C([H])N(N=N3)C([H])([H])C([H])([H])C(=O)N([H])C3=C4C([H])=C([H])C([H])=C([H])C4=C([H])C([H])=C3[H])C2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NN(C([H])=N1)N(C([H])([H])C1=C([H])C([H])=C([H])S1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C(O[H])C(=O)N2C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]O\N=C(/[H])C1=[N+](C([H])=C([H])N1C([H])([H])[H])C([H])([H])O[C@@]([H])(C([H])([H])C#C[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])N(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N(C(=O)C1=C(N([H])C2=C([H])N=C([H])N=C2[H])C([H])=C([H])C(=N1)C([H])([H])OC([H])([H])[H])C1=C([H])C(=NN1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C([H])C(OC([H])([H])[H])=C([H])C3=C([H])C([H])=C1[H])=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC2=C1C(=O)N(C(=O)N2C([H])([H])C1=C([H])C([H])=C(C([H])=C1Br)C1=C([H])C([H])=C([H])C([H])=C1C1=NOC([O-])=N1)C([H])([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(\C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
CN(C)C1=NC(=NC2=CC=C(C=C12)C1=CNN=C1)[C@@H](N)CC1=CC=CC(F)=C1
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1(N2C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@@]3([H])N([H])C([H])([H])C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=N\C(=C(\[H])C2=C([H])N([H])C3=NC([H])=C([H])C([H])=C23)C(=O)N1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C1=NC(=NO1)C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C(N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=NC2=C([H])C3=C(C([H])=C2C(=C1[H])C(F)(F)F)[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])N3[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2C([H])([H])[H]
[H]N(C1=NC(=NC2=C(C#N)C([H])=NN12)N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3F)C([H])=C2C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)[N+]([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1(\C([H])=C(/[H])C([H])([H])C(F)(F)C(F)(F)C(F)(F)F)C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])C4=C([H])C(OC([H])([H])[H])=C([H])C([H])=C4[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]N(C([H])([H])C1=NC(=C(N1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(F)=C1S(=O)(=O)C1=C(C([H])=C([H])C(Cl)=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])S(=O)(=O)C(F)(F)F)C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]3([H])C([H])([H])C([H])([H])[C@@](O[H])(C#CC4=C([H])C([H])=C(C([H])=C4[H])C([H])([H])N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]21[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[H]
OC(CNC1CCN(CC1)C1=NC=NC2=C1C(=CS2)C1=CC=CC=C1)COC1=CC=CC(O)=C1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(Cl)C([H])=C2N=C([H])C(=C(OC([H])([H])C([H])([H])[C@]3([H])N([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C2=C1[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(Cl)=C([H])C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(\C([H])=C(/[H])C2=C([H])C([H])=NC([H])=C2[H])=C([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]C1=C(N=NN1C([H])([H])C([H])([H])F)C([H])([H])N1C(=O)C(=O)C2=C1C([H])=C([H])C(=C2[H])S(=O)(=O)N1C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC1=C([H])C([H])=C(F)C([H])=C1F
[H]N([H])C1=C(C([H])=NC2=C(C([H])=NN12)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N([H])C1=C(C([H])=NC(=N1)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])C(=O)C1=C(OC([H])([H])[H])C([H])=C(F)C(F)=C1F
[H]OC1=C2\C(=C(\[H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C([H])([H])O[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])[C@]1(SC(=NC1=O)N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C([H])([H])N([H])C1=NC([H])([H])C([H])([H])N1[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C1=C([H])SC([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])O[H]
[H]N(C1=NC([H])=C(C(SC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])=N1)C(F)(F)F)C1=C([H])C([H])=C2N([H])C([H])=NC2=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])[C@@]([H])([C@]1([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=NC2=C1C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]C1=C2N=C(C(=C(N2N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])[C@@]([H])(N(C([H])([H])C(=O)N([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(S1)C([H])([H])N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])[C@@]([H])(O[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])S1
[H]N([H])C(=O)C(=O)[C@@]([H])(N([H])C(=O)C1=C(C(=O)C2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C2O1)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=NS2)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C([H])C(C(=N[H])N([H])[H])=C(F)C([H])=C2N1[H]
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[H]ON([H])C(=O)C1(C([H])([H])S(=O)(=O)N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C(=O)O[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C(S1)C1=NN=C2S\C(=C(\[H])C3=C([H])C([H])=C([H])C(=C3[H])[N+]([O-])=O)C(=NN12)C1=C([H])C(F)=C(Cl)C([H])=C1Cl)C([H])([H])[H]
[H]N([H])C1=NC2=C(C(=O)C3=C([H])C([H])=C(C([H])=C23)C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C(O[H])C([H])=C2C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N(C(=O)C1=C(Cl)C(=C([H])S1)C([H])([H])N(C1=NC([H])([H])C([H])([H])S1)C([H])([H])[H])C1=C(C([H])=C(Cl)C([H])=C1OC([H])([H])[H])C(=O)N([H])C1=NC([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C(N=C1C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]N([H])C1=NC([H])=C([H])C(OC2=C(F)C([H])=C(N([H])C3=C(C([H])=C([H])C([H])=N3)C(=O)N([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])=C1[H]
[H]OS(=O)(=O)C1=C2OC([H])([H])OC2=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])N1N=C([H])C2=C1N=C(N([H])[H])N1N=C(N=C21)C1=C([H])C([H])=C([H])O1
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])[C@]([H])(O[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=NC([H])=C2Cl)C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C1=O)[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1C(=O)N(C([H])([H])[H])[C@@]2(C1=O)C([H])([H])C1=C(C([H])=C3N([H])C(=NC3=C1[H])C([H])([H])N1C(=O)N(C3=C1C([H])=C([H])C([H])=C3[H])C1=C([H])C([H])=C([H])C([H])=N1)C2([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(N2C(=NN=C2C(F)(F)F)[C@@]1([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)O[C@]2(C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])N(C(=O)C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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COC1=CC(=CC(=C1)N1CCOCC1)C(C)C#CC1=C(N)N=C(N)N=C1C
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CONc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
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[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N([H])C2=C([H])C([H])=C(OC([H])([H])[H])N=C2[H])C([H])=NC([H])=C1[H]
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CC1=C(SC(=C1)C1=CC=C(O)C=C1C)C1=C(C)C=C(O)C=C1
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[H]C([H])=C([H])C([H])([H])N(C(=O)OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(C([H])=C(Br)C(=C1[H])N1C2=C(N=C1C([H])([H])[H])C(=NC(=N2)C([H])([H])[H])N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]12O[C@@](OC1([H])[H])(C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]2([H])O[H]
[H]N(C(=O)O[C@@]1([H])[C@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])N=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C(=O)OC2=C([H])C(OC([H])([H])C3=C([H])C(=C([H])C([H])=C3[H])C([H])([H])[H])=C([H])C([H])=C12
[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])=C(O2)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2O1
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(=O)N([H])C(C1=NN=NN1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])\C(=C(\[H])C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])N=C23)C2=C([H])C([H])=C(F)C([H])=C12
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C(O[H])C([H])=C2[H])[C@]2([H])[S@@](=O)[C@@]1([H])C([H])([H])[C@]2([H])S(=O)(=O)OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])SC(=O)[C@]([H])(C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C#N)C1=C(Cl)C([H])=C([H])N=C1N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(Cl)=C1C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C(=O)OC([H])([H])C([H])([H])[H])C2=C(S1)C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C(S1)C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(OC(=O)[C@@]1([H])N(C(=O)[C@]([H])(C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]ON([H])C(=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C(Cl)=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])[H])C2=C1C1=C(C3=C2C([H])([H])N([H])C3=O)C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C(=C([H])C(=N1)C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C([H])=C(F)C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])[C@@]([H])(C([H])=C([H])[H])C([H])([H])[H]
[H]C1=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C(\N=N\C2=C([H])C(Cl)=C(F)C([H])=C2[H])=N1
[H]N(C(=O)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C([H])([H])C1(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=NN1C([H])([H])C([H])([H])N([H])[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H]
[H]OC([H])([H])[C@@]1(ON=C2N1C([H])([H])C([H])([H])C([H])([H])\C2=C(\[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])N1C([H])=NC(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C(Br)=C2[H])C2=NC([H])=C([H])C([H])=C2C1=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(F)C([H])=C([H])C(=C1[H])[C@@]1([H])OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])=NC2=C1N=C(N=C2C#N)C1=C([H])C(=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C2C(SN=C2N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C3=C4N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C4=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H]
[H]OC(=O)C(OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C(C([H])=C1C(F)(F)F)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=N[C@@]([H])(N([H])C2=C([H])C([H])=C([H])C(F)=C12)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])\C(=N/OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC([H])=NC(N2C([H])([H])C([H])([H])N(C(=O)N([H])C3=C([H])C([H])=C(C([H])=C3[H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])=C1\C([H])=N\OC([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(SC(=O)C([H])([H])N(C2=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(O2)C([H])([H])N([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
COC1=CC(=CC=C1Cl)N1CCN(CC1)C(=O)CN1N=C(C#N)C(Cl)=C1C
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C([H])C(OC3=C4C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C4=NC([H])=C3[H])=C([H])C([H])=C12)C1=NC([H])=C([H])S1
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(N=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(N(C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C23)C([H])=N1
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)C2=C([H])N(C(=N2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3N=C2[H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
C[C@@]1(N=C(N)OCC1(F)F)C1=CC(NC(=O)C2=NC=C(C=C2)C#N)=CC=C1F
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[H]N1C(=O)C(C2=C([H])OC3=C([H])C([H])=C([H])C([H])=C23)=C(C1=O)C1=C([H])N(C2=C([H])C([H])=C(Br)C([H])=C12)C([H])([H])[H]
[H]C1=C([H])C(OC2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)=C(OC([H])([H])[H])C([H])=C1[H]
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[H]N([H])C1=NC2=C([H])C([H])=C([H])C(Cl)=C2[C@@]([H])(N1[H])C([H])([H])[H]
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[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=C(C2=C1N=C([H])N=C2N([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]O[C@]12C([H])([H])N(C([H])([H])[C@@]1([H])N1N(C(=O)C([H])=C([H])C1=O)C([H])([H])[C@]2([H])OC(=O)N([H])C1=C([H])C([H])=C([H])S1)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]C1=NN=C(N1C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl)C1=C(Cl)C(Cl)=C([H])C([H])=C1[H]
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[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2I)C([H])([H])C1([H])[H]
CCCCCCCCCC[Si](C)(C)CCC(=O)NC(CC1=CC=C(C)C=C1)C1=CC=CC=C1
[H]C1=C([H])N=C(S1)C1=NC(Cl)=NC2=C1SC([H])=C2[H]
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[H]N(C(=O)C1=C([H])C([H])=C2C([H])=C1N([H])C1=C(Cl)C([H])=NC(=N1)N([H])C1=C([H])C(=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(F)(F)F)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(C(=O)OC([H])([H])N2C(=O)C3=C(C([H])=C(F)C([H])=C3S2(=O)=O)C([H])(C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
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[H]C1=C([H])C(=C([H])C([H])=C1C#N)N1C(=NC(=C1C(F)(F)F)C1([H])C([H])([H])C1([H])[H])[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H]
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[H]O[P@](=O)(C([H])([H])[H])[C@]([H])(C(=O)N([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N1[C@]2([H])C3=C(N(C4=C(OC([H])([H])[H])C([H])=C(C([H])=C34)S(=O)(=O)C3=C([H])C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]OC1=C2C(OC(=C2C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C(=C1[H])C1=NN(C(=O)N1C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]([H])([C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H])[C@]1([H])N([H])C([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)N([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C(Cl)C([H])=C(C([H])=C1[H])C([H])([H])OC1=C2C(=NC(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C([H])=C([H])N1N=C([H])C(=N1)C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H]
[H]N(C1=NC(N([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])=C(C([H])=N1)C(F)(F)F)C1=C([H])C2=C(N([H])C(=O)C2([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=C2C([H])=C(C(=O)N(C2=C1[H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C2=O)C([H])([H])C1([H])[H]
[H]C1=NN=C2N1C1=C(SC(=C1C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(C(=O)N([H])[C@@]([H])(C1=NN=C(N1C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C1\C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
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[H]N([H])C1=NC([H])=C([H])C(=N1)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])O1
[H]N(C(=O)C1=C([H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC(Cl)=C([H])N(C1=O)[C@]([H])(C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C1=C(C#N)C([H])=C(Cl)C([H])=C1Cl
[H]N(\C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)S1)N1N=C([H])[C@]([H])(C([H])([H])C([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
CS(=O)(=O)C1=CC=C(C=C1)N1CCN(CC1)C1=NC=C(S1)C(O)(C(F)(F)F)C(F)(F)F
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[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C(=O)N([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)=C([H])N=C1[H]
[H]N1C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C3N=C(N(C(=O)C3=C2[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2S1(=O)=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1N1N=C(C2=C1C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(F)(F)F
[H]N1C2=C(C([H])=C([H])C([H])=C2OC(=O)C([H])([H])[H])C2=C([H])C([H])=NC(=C12)C1=C([H])\C2=C([H])\C([H])([H])\C([H])=C([H])/C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N@@]3C([H])([H])C([H])([H])[C@]1([H])[C@]1(C([H])([H])[C@]4([H])\C([H])=C([H])/C([H])([H])C([H])([H])C([H])([H])C([H])([H])N4[C@@]21[H])C3([H])[H]
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[H]C1=C(Cl)N(C2=NC(=C(N12)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C(F)(F)F)C(F)(F)F)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)[C@]([H])(OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C2C(N([H])C3=C(N([H])C2=O)C([H])=C(C([H])=C3[H])C(C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N2C(=O)C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N(N=C1C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3F)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C(N2N=C(OC([H])([H])[H])C(N(C([H])([H])C([H])([H])C([H])([H])[H])C3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C2S1)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1Cl)C([H])([H])OC([H])([H])[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C(Cl)C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C2C(=O)OC([H])([H])C2=C(C(OC([H])([H])[H])=C1C([H])([H])C([H])([H])N([H])S(=O)(=O)C([H])([H])S(=O)(=O)N([H])C([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=NS2)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C(=O)C3=C([H])C([H])=C([H])C([H])=C3C2([H])[H])C([H])([H])C1([H])[H]
[H]N1[C@]2([H])C3=C(N(C4=C(C([H])=C(C([H])=C34)S(=O)(=O)C3=C([H])N(C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@@]1(O[H])C2=C(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])=C([H])C(=C2[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])[C@@]([H])(C1=C([H])C([H])=C(OC([H])(F)F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(OC([H])([H])[C@]([H])(N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])Cl)C([H])([H])[H])C([H])=C1[H]
[H]C1=C(C([H])=C(SC([H])([H])[H])C(=C1[H])N1N=NC2=C1N=C(N=C2N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])S(=O)(=O)[C@]1([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]1([H])OC(=O)C([H])([H])[H]
[H]O[C@@]([H])(C(\[H])=C(/[H])C1=C(N(N=C1C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]S\C(=N/C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])\C(\[H])=C(/[H])C2=NC3=C(O2)C([H])=C([H])C(=C3[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C1O[H]
[H]C1=C([H])C([H])=C2C(SN=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4N3C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H]
[H]N(C(=O)C1=C2N([H])[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C(N2N=C1C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C2=C([H])N=NC(C3=C(F)C([H])=C([H])C([H])=C3[H])=C2C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(OC3=C(C([H])=C(OC(=O)C([H])([H])[H])C([H])=C3[H])S2(=O)=O)=C1[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(C(=O)N([H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)C4=C([H])C([H])=C([H])N4[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(N([H])C(=C2[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])C(C(=O)N([H])[H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]