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[H]N(C(=O)C([H])([H])C1=C(N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])[H])[C@]([H])(C1=NC2=C(N1[H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])N2C(=NO[C@]2([H])C2=C([H])C([H])=NC([H])=N2)C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1N(C(=O)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C(Cl)=C1[H])[C@]1([H])N([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C3C(=NC([H])=C2[H])N([H])C([H])=C13
[H]N1C(=O)S[C@@]([H])(C1=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C(C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
CC1=NC=CC=C1OC1=C(F)C(=NC=N1)N1C2CC3CC1CC(C2)N3C(=O)OC(C)(C)C
[H]N1\C(SC([H])([H])C1=O)=C(\[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N([H])C(=O)C2(N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C2=C([H])N=C(OC3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])C1=O
[H]C1=C([H])C([H])=C(S1)C([H])([H])N(C(=O)O[C@@]1([H])C([H])([H])[N@+]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=C([H])C(=N1)C([H])([H])[C@]1([H])C([H])([H])N([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=C3N=C(N([H])C3=C2[H])C2=C(N([H])C([H])([H])[C@@]([H])(O[H])C3=C([H])C([H])=C([H])C(Cl)=C3[H])C([H])=C([H])N([H])C2=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]2([H])C3=C(C([H])=C([H])C([H])=N3)C([H])([H])SC3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])C(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])[N+]([O-])=O
[H]C1=NN2C(=N1)N=C(C([H])=C2N1C([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C([H])C([H])=C3S2)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C(=O)C1=C([H])C2=C(S1)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1F)N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])SC1=C([H])N([H])N=N1
[H]C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=NC([H])=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(N1C([H])([H])[H])C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N1C([H])=C([H])N=C(N([H])C([H])([H])C2=NON=C2C([H])([H])[H])C1=O)C([H])([H])C([H])([H])[H])C(=O)C([H])([H])N([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]O[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C1=C([H])C(OC([H])(F)F)=C(OC([H])(F)F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=[N+]([O-])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])[C@@]1([H])C([H])([H])[C@]([H])(O[C@]1([H])C1=C(O2)C([H])=C([H])C(F)=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])([H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]1([H])[C@@]2([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC([H])([H])C([H])([H])[C@]2([H])N([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])N1C([H])=NC2=C1C([H])=NC([H])=C2[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=O)N([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)=C([H])C([H])=C2O1
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C([H])C(=N2)C([H])([H])[H])C1=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)[C@@]2([H])N([H])C(=O)N([H])C2([H])[H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NN2C(N=C([H])C([H])=C2[C@@]2([H])C([H])([H])[C@@]3([H])N(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C1C1=C([H])C([H])=C(Cl)C(OC([H])([H])[H])=C1[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC2=C1N([H])C([H])=NC([H])([H])[C@@]2([H])O[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=NC(=C1C#N)S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C(F)=C(C([H])=C1[H])N(C(=O)C1=C(ON=C1C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C(=O)C1=C([H])C2=C(C([H])=C([H])C([H])=C2S1)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C(F)=C([H])C([H])=C1F)[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C(Cl)C(Cl)=C2[C@@]([H])(N1[H])C([H])([H])C([H])([H])[H]
[H]N(N=C(C#N)C#N)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1[H])C(F)(F)F
[H]C(=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(C2=C1OC([H])([H])N(C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C2([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C([H])=C([H])N=C12)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(OC3=NC([H])=C(Cl)C([H])=C23)C(=N1)N1C([H])([H])C([H])([H])[C@@]([H])(N([H])[H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(O[C@]([H])(N2C(=O)C([H])([H])[H])C2=C([H])C(Br)=C(OC([H])([H])[H])C([H])=C2[H])N=C(SC([H])([H])C([H])([H])[H])N=N1
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C2=C(C3=C(N2C2=C([H])C(N([H])[C@@]([H])(C([H])([H])[H])[C@]1([H])C([H])([H])[H])=C(C([H])=C2[H])C(=O)N([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C3=O)C([H])([H])[H]
FC(F)(F)OC1=CC=C2N(CC3=CC=C(C=C3)C3=CC=CN=C3)C(=O)C(=O)C2=C1
[H]N(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])C([H])=C(C#CC3=C([H])C([H])=C([H])N=C3[H])C([H])=C12
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]3([H])C([H])([H])C([H])([H])[C@@](O[H])(C#CC4=C([H])C([H])=C(C([H])=C4[H])C([H])([H])N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]21[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])[C@@]([H])(S[H])C(F)(F)C(F)(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)C(OC1=C([H])C(=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])[C@]([H])(N([H])C(=O)C4=C([H])C([H])=C([H])C(=C4[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(=O)N(C2=O)C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N(C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
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[H]N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]C1=C(I)C(=O)C([H])([H])[C@@]2([H])N1C([H])([H])C([H])([H])C2([H])[H]
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[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=NN([H])C2=C([H])C(=C([H])C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N1C2=C([H])C(=C(Cl)C([H])=C2N=C(C2=C([H])C([H])=C([H])C(=C2[H])N2N=NC([H])=C2[H])C([H])([H])C1=O)C(F)(F)F
[H]N([H])C1=N[C@@](C(=O)N1C([H])([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C(N=C(C([H])=C2[H])C([H])([H])N([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C(=N1)N([H])[H]
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[H]SC([H])([H])[C@@]([H])(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S([O-])(=O)=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C([H])S1)C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])=C(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])C1=C([H])SC2=C1C([H])=C([H])C([H])=C2[H])[C@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@@]([H])(C(\[H])=C(/[H])C2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2C([H])=C([H])C(=C([H])C2=C1[H])C([H])([H])N(C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(C#N)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(N=C(N2N=C(N=C12)S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]1([H])[C@]([H])(O[H])[C@]2(C(=O)N([H])C([H])([H])[H])C([H])([H])[C@]2([H])[C@@]1([H])N1C([H])=NC2=C1N=C(N=C2N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N(N=N1)[C@]([H])(Br)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C2([H])[H])[C@]1([H])N([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C(=O)C(=O)N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]\C(C1=C(N(N=C1C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])=C1/C(=O)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N(C1=C(C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C(OC([H])([H])[H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])[N+]([O-])=O)[C@@]([H])(C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])SC([H])([H])C([H])([H])N1C(=O)SC([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC([H])([H])[H]
[H]C1=C(SC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=[N+](C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C1SC(C#C[C@@]1([H])N([H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])[H])C1([H])[H])=C2[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C(Cl)=C1[H]
[H]N([H])C(=NC(=O)C1=C(C([H])=C(O1)C1=C(Cl)C([H])=C([H])C(Cl)=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])[H]
[H]SC(=N[H])N1N=C(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
[H]N1C(=C([H])C(C(=O)N2C([H])([H])C([H])([H])N(C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C([H])N=C(C([H])=C1C([H])([H])[H])N1C([H])([H])[C@@]([H])(C2=C([H])C([H])=C(C#N)C([H])=C2[H])[C@]2(N(C(=O)N(C2=O)C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])[H])C1([H])[H]
[H]N([H])C1=NC2=C(C(=O)C3=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C23)C(=N1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[O-]C(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.CC1=NC2=C(OCC3=C(Cl)C=CC(=C3Cl)S(=O)(=O)NC3(CCOCC3)C(=O)N3CC[N+](C)(CCCC[N+](C)(C)C)CC3)C=CC=C2C(C)=C1
[H]OC(=O)C([H])([H])N1N=NC(=N1)C1=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2Br)=NO1
[H]N(C(=O)C([H])([H])N1C([H])([H])[C@]([H])(OC([H])([H])C([H])(F)F)[C@@]([H])(N([H])C(=O)C2=C([H])C([H])=C(Cl)S2)C1([H])[H])C1=C([H])C([H])=C(C([H])=C1F)N1C([H])=C([H])C([H])=C([H])C1=O
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C2N=C([H])C([H])=C([H])C2=C1[H])C1=NC([H])=C(S1)C1([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C(=O)N([H])[H])C([H])([H])[H]
CCCCCCCCN1C=C(CC(N)=O)C2=CC(F)=CC=C12
[H]N([H])[C@]1([H])C([H])([H])N(C2=C(C#N)C3=C(N2C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[S+]([O-])(=NC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C(Cl)C([H])=C1[H]
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[H]N([H])C(=O)C1=C2N([H])C([H])([H])[C@]3([H])N(C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=C(C4=C(N3C(C([H])=C1[H])=C2[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C4=O)C([H])([H])[H]
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[H]N(C(=O)N([H])[C@]1([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C(N([H])C2=NC3=C(N=C([H])N3[H])C(=N2)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=NC(=C(N=C1C([H])([H])C([H])([H])[H])N([H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(N([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=N[H])N([H])[H]
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[H]N(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C(=O)C2=C(N=C(S2)C([H])([H])[H])C1=O
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C(=O)N(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]O[P@@](=O)(C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC(=O)C(=C(/[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C2=C([H])C([H])=C([H])N=C12)C([H])(C([H])([H])[H])C([H])([H])[H])\C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
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[H]OC([H])([H])C1=C([H])C([H])=C([H])C2=C1S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1O2
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])N1N=C([H])C(C(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1SC([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])[C@]2([H])N(C3=NC4=C(S3)C([H])=C(OC([H])([H])[H])C([H])=C4[H])C(=O)[C@@]([H])(C([H])([H])[H])[C@@]12[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H][C@@]12C[C@]1([H])[C@H]([C@H](O)[C@@H]2O)N1C=NC2=C1N=C(N=C2NCC(C1=CC=CC=C1)C1=CC=CC=C1)C#CC1=CC=CC=C1Cl
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C2=C([H])C(=C([H])C([H])=C2SC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N([H])[H])[N+]([O-])=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]C1=C([H])N(C(=N1)C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C2=C(C(=O)N(N2C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[C@@]4([H])OC([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
[H]N1N=C(C2=NC3=C(N2[H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C(\C([H])=C(/[H])C2=C([H])N=C([H])C(OC([H])([H])[H])=C2[H])=C1[H]
[H]OC1=C(C(=O)N([H])C2=NC([H])=C([H])S2)C(=NC2=C(C([H])=C([H])C([H])=C12)C(F)(F)F)C(F)(F)F
[H]N=C(N([H])C1=NC(=C([H])S1)C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]2([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])SSC([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC(C)C1=CC=C(NC(=O)OC2=CC=C3N(C)C4[C@@](C)(CC[N]4(C)C)C3=C2)C=C1
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C1\C2=C(C([H])=C([H])C([H])=C2[H])N(C(=O)C2=C(Cl)C([H])=C(C([H])=C2[H])N2N=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]ON([H])C(=O)C([H])([H])N(C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=NC2=C3C(=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C(OC([H])=C1[H])C([H])([H])[H])C1=NC2=C(S1)C([H])=C(OC([H])([H])[H])C([H])=C2[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1N=C([H])C2=C([H])C(F)=C([H])C([H])=C12
COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccc2[N+]([O-])=O)CC1
[H]N([H])C(=O)C1=C(N([H])C(=C(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C(C(=O)OC([H])([H])[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])OC([H])([H])C([H])([H])N([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])C2=C([H])C(O[H])=C(C(O[H])=C2[H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
CO\N=C1/C[C@H](N(C1)C(=O)C1=CC=C(C=C1)C1=CC=CC=C1)C(=O)NCC(O)C1=CC=CC=C1
[H]OC([H])([H])C([H])([H])N(C(=O)C1=C([H])C2=C(N([H])C(=C2C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N1C2=C(C([H])=C(Cl)C([H])=C2[H])[C@@]2(N(C([H])([H])[H])C([H])([H])[C@]([H])(C3=C([H])C([H])=C(F)C([H])=C3[H])[C@]22C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C2([H])[H])C1=O
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C(N([H])C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]N(C1=NN=C(C2=C1C([H])=C(N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1Cl)C([H])([H])[H])C1=C([H])C(F)=C(F)C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C1=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C1[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N1N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]C1=NN(N=C1[H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)S(=O)(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])C(=O)C1=C([H])C([H])=C([H])O1
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]OC1=C(O[H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C2=C(O[H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])O[H]
[H]C1=NN(C2=NC([H])=NC(OC3([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2C([H])([H])OC([H])([H])C([H])=C([H])[H])C([H])([H])C2=NC([H])=C(S2)C2=C([H])OC([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]OC1=C([H])C(O[H])=C2C(=O)C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3Cl)OC2=C1[C@@]1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])O[H]
[H]C1=NN(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C3C(=N2)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])OC1=NSN=C1C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)C1=C(N=C(S1)C1=C([H])C([H])=C(OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(C#N)=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C(C(=NC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[S@](=O)C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C([H])C4=C(N=C(O4)C(F)(F)C(F)(F)F)C([H])=C3C([H])([H])C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])N([H])C1=O)C1=NC(N([H])C([H])([H])[H])=C([H])N=C1[H]
OCC1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC(SC([H])([H])[H])=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])=NC(=C1[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(\N=C(/N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])N([H])C(=O)[C@]2([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C3=C([H])C([H])=C([H])C([H])=C3N(C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C(OC2=C1[H])C([H])=C([H])C(OS(=O)(=O)C([H])([H])[H])=C3[H]
[H]OC1=C(C(=C2O[C@]([H])(SC2=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])O[H])C([H])([H])[H])C([H])([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C1=NC([H])=NC2=C1N([H])C([H])=C2[H])C1=C([H])C(Cl)=C(OC2=C([H])C([H])=C([H])C([H])=C2F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(N=C(N2C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C2=NN=NN2[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C(F)=C2[H])C2=NC3=C(C(=NS3)C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(=O)N2[H])C([H])([H])C1([H])[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C#CC1=C([H])C([H])=C([H])C([H])=C1[N+]([O-])=O)C1=C([H])C([H])=C([H])C([H])=N1
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=N3)C([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C(S1)C([H])=C([H])C(=C2[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C1=C(Cl)C(=C([H])S1)C([H])([H])N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(SN=C2C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N=C1C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C#N)[C@@]([H])(C2([H])[H])[C@]1([H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC3=C(C([H])=C(F)C([H])=C3[H])C(=O)N2C([H])([H])C2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C(F)(F)F)C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C2SC3=C(C([H])=C([H])C([H])=C3[H])C(=NC2=C1[H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C(=O)N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=NC2=C(S1)C([H])=C([H])C(=C2[H])C(F)(F)F
[H]N(C1=NC([H])=C([H])C(=N1)C1=C(N([H])C(C#N)=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
CCCC1=C(C(=O)OCC)C(C(=O)OCC)=C2N1N=C(C=C2C1=CC(F)=CC=C1)N1CCOCC1
[H]N(C1=C([H])C([H])=C2C(N([H])C(=C2C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])[H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C2C([H])=NC([H])=C([H])C2=NC(=C1C#N)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N1C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]N(C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)C1=C([H])C([H])=C(O1)C([H])([H])N(C([H])([H])C#N)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C(Cl)=C1[H]
[H]C1=C([H])C([H])=C2N=C(SC2=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]C1=C(C2=C(O1)C([H])=C([H])C(=C2[H])C1=NN=C(O1)SC([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])C(F)(F)F)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C3=C(C([H])=C(S3)C([H])([H])C([H])([H])C([H])([H])[H])[C@]21[H]
[H]N(C(=O)C1=C(N(C(=O)N([H])[C@]1([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(C#N)(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(OC2=C(C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[H]
[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])C([H])([H])C([H])([H])O[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C2C([H])=C([H])N=C([H])C2=C([H])C([H])=C1[H])C1=C(C(=O)OC([H])([H])[H])C(=C([H])S1)C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])[H])C([H])([H])N([H])C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])=N1
[H]N1C([H])([H])[C@@]2([H])C([H])=C(C3=C([H])N=C([H])C(C#N)=C3[H])C([H])([H])[C@@]([H])(C1([H])[H])C2([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])C3([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(O1)C(=O)N1N=C(N=C1SC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C(=O)N([H])C1=C([H])N=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])O[C@]([H])(C1([H])[H])[C@]([H])(OC1=C(OC([H])([H])[H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C(N(C2=C([H])C([H])=C(F)C([H])=C12)S(=O)(=O)C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(\C([H])=C(\[H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC(=C1[H])C([H])([H])N(C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C2=C([H])C3=NC(C#N)=C([H])C(=C3C([H])=C2C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=NC([H])=C(C([H])=C1[H])[C@]([H])(C(=O)N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C2/S\C(=N/C3=C([H])C([H])=C([H])C([H])=C3[H])N(C2=O)C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC(=C([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)[C@]([H])(C([H])([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=NC2=C(C([H])=C(Cl)C([H])=C2[H])C(O[H])=C1N=O
[H]N1N=C(C(=C1C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=NC(=NC2=C1C(=C(N2[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2N=C(C(OC([H])([H])C3=C([H])C(OC4([H])C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])=NC(=N3)N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=NC2=C1[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC(C2=C([H])C([H])=C([H])O2)=C(N=C1[H])C1=NC([H])=NC([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1(O[H])C2=C(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])=C(Br)C(Cl)=C2[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C(=O)C1=C([H])N(C(=O)C(C#N)=C1[H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=NOC(=C1[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])OC2=C(C([H])=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])N=C1N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])C2=C([H])C(=C(Cl)C([H])=C2[C@@]2(C1([H])[H])C([H])([H])C([H])([H])N(C(=O)[C@]1([H])C([H])([H])N(C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(F)C([H])=C1F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]OC1=C2\C(=C(\[H])N3C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)[C@@]([H])(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
O=C(NC1=CC=CC=C1)NC1(CCC1)C1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
[H]N([H])C1=NC2=C([H])C([H])=C(C([H])=C2C(=N1)N([H])[H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=NC2=C([H])C([H])=C(N([H])C([H])([H])C3=C([H])C([H])=C4OC([H])([H])C([H])([H])OC4=C3[H])C([H])=C12)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(N(C(=N1)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C(=O)O[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1C([H])([H])C([H])([H])N(C2=C(C#N)C3=C(N2C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C(=O)N(C([H])=N3)C([H])([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC(=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
CN1N=C(CC(=O)NC2=CC=C(OC(F)(F)F)C=C2)C2=CC=CC=C2C1=O
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(C(=O)N([H])S(=O)(=O)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])OC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(=C1[H])[C@@]1([H])SC(=NN1C(=O)C1=C([H])C(F)=C([H])C(F)=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C([H])C(=N1)N1C([H])([H])[C@@]([H])(C2=C([H])C([H])=C(C#N)C([H])=C2[H])[C@]2(N(C(=O)N(C2=O)C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])[H])C1([H])[H]
[H]N(C1=C(C(Cl)=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C(F)=C1[H])[C@@]1([H])N(C(=O)[C@]3([H])N(C(=O)C(=O)C4=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C4[H])[C@@]1([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@@]([H])(OC1=NC2=C(C(OC([H])([H])[H])=N1)C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])SC([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C2N=C([H])N([H])C2=NC(=N1)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]1([H])N2C(=O)[C@@]([H])(N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3C(F)(F)F)C([H])([H])\C([H])=C([H])/C([H])([H])[C@@]2([H])C([H])([H])OC1([H])[H]
[H]O[C@@]([H])(C([H])([H])[H])[C@]([H])(SC1=C(Br)C([H])=NC(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])[S@](=O)(=N[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=NC1=NC([H])=C(Cl)C2=C([H])C([H])=C(C([H])=C12)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])N([H])[H]
[H]\C(=C1/C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=NC(=NC2=C1C([H])=NN2C([H])([H])[H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C([H])N=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])[H]
CCN1CCN(CC1)C1=C2C=C(NC2=NC(N)=N1)C1=CC=C(F)C=C1
[H]N1C(=O)N(C([H])([H])[C@]1(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[C@@]([H])(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C(=O)N([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])SC([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(OC2([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[C@]([H])(C1=C([H])C(\C([H])=C(/[H])C2=NC3=C([H])C(Cl)=C([H])C([H])=C3C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])O[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=NS2)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C3N(C(=O)C([H])([H])C3=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
CN1C(=CC2=C1C=CC=C2)C(=O)NC1=CN=C(C=C1)N1CCN(CC1)C(=O)NC1=CC=CC=C1F
[H]OC1=C([H])C(N([H])C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C2=NC([H])=NC(=N2)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C(=C([H])N=C1[H])C1=C([H])SC([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])[H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])=N1
[H]OC(=O)C1=C([H])C2=C(N([H])C(=N2)N2C([H])([H])C([H])([H])C3(OC(=O)C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])=C1[H]
CCC(=O)C1=CC(NC(=O)N(CCC(C2=CC=CC=C2)C2=CC=CC=C2)CCN2CCOCC2)=CC=C1
[H]C1=C([H])C2=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C3=C([H])C4=C(C([H])=C3[H])N(N=N4)C([H])([H])[H])[C@@]1([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])S(=O)(=O)N(C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N2C([H])([H])C3=C(N=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]OC1=C2C([H])=C([H])C(=C([H])C2=NN1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=NC([H])=C([H])C([H])=C1C(F)(F)F
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1N=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C1=NC2=C(OC([H])([H])[H])C([H])=C([H])C(N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])=C2S1
[H]OC(=O)[C@]([H])(N1C([H])([H])C([H])([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])C([H])([H])N2[C@@]3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])[C@]([H])(N2C4=C(N=C2C([H])([H])[H])C([H])=C([H])C([H])=C4[H])C3([H])[H])C([H])([H])C1([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C2C(=NC(=N1)N([H])[H])N([H])C(=C2SC1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=NC2=C(C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])N1C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NN=NN1[H]
[H]N1[C@]([H])(SC([H])([H])[C@@]1([H])C(=O)C1=C([H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C(Br)=C2[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C2N([H])C(=O)N([H])C2=C([H])C([H])=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C2C(=NC(=N1)N([H])[H])N([H])C([H])=C2C([H])([H])N([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(C1=C([H])SC(=C1[H])C([H])([H])[H])(C1=C([H])SC(=C1[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[N+]2(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])[C@]([H])(N(C(=O)C([H])([H])N1N=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C2=C(Cl)C(F)=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])C(=O)C1=C([H])C(=C([H])N=C1[H])C(=O)\N=C(\N([H])C1=C([H])C2=C(OC(=C2[H])C([H])([H])[H])C([H])=C1[H])N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(S1)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]\C(=C(\C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])ON=C3C4=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C4OC([H])([H])[C@@]23[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC(=O)[C@]([H])(C1=C([H])C(N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
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[H]N(C(=O)C1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=O)N([H])C1([H])[H])C1=C3C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(OC([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)N=C(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=C(C(=O)O[C@@]([H])(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=C2N1C([H])([H])C([H])([H])N(C2=O)C([H])([H])C([H])([H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN=C(O1)C(=O)N([H])C1=C([H])C2=C(N([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=NC(=C(S1)C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
NC1=NC(=CC=N1)N1C=C(C2=C1C=CN=C2)C1=CC=C(Cl)C=C1
NC(=O)C1=C(NC(=C1)C1=C(F)C=NC(N)=N1)C1=CC=CC=C1
[H]O[C@@]1(C#CC([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])[C@@]3([H])C(=C4C(=C([H])C(=O)C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])[C@@](Cl)(C3=C([H])C(Cl)=C(N(C([H])([H])[H])C([H])([H])[H])C(Cl)=C3[H])C([H])([H])[C@]12C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(F)=C(C(=C1[H])C1=C([H])C2=NN=C(N2N(C1=O)C([H])([H])C([H])([H])[H])C1=C(F)C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C2=C1C([H])=C(N=N2)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C#CC1=NC2=C(N=C([H])N2[C@]2([H])[C@@]3([H])C([H])([H])[C@@]3(C(=O)N([H])C([H])([H])[H])[C@@]([H])(O[H])[C@@]2([H])O[H])C(=N1)N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(OC2=C(OC(=C([H])C2=O)C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(N=N2)C2=NC([H])=C(O2)C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N1N=C(C2=C1N1C(=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]13[H])N(C2=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(SC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C(C([H])=C([H])C([H])=N1)C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C2([H])N(C([H])([H])C3=C([H])C([H])=C4C([H])=C(F)C([H])=C([H])C4=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1(O[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C(=N\OC([H])([H])C([H])([H])[H])\C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)C2=C(N=C(N=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)C1=C(Cl)N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=NN([H])N=N2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C2C([H])=C3C([H])=C([H])C([H])=C([H])C3=C([H])C2=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(N=C(N([H])[H])N([H])[H])N=C1[H]
[H]OP(=O)(O[H])OC([H])([H])[C@@]1([H])O[C@]([H])(N2C([H])=NC3=C(N=C(Cl)N=C23)N([H])C([H])([H])[H])C([H])([H])[C@]1([H])OP(=O)(O[H])O[H]
[H]N(C(=O)C1=C(N(N(C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC2=C3C([H])=C([H])C(OC([H])([H])[H])=C([H])C3=NC([H])=C2[H])C(F)=C1[H]
[H]C1=C([H])C(=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])[C@]2([H])C(=O)N(C3=C([H])C([H])=C(OC([H])([H])C(F)(F)F)C([H])=C3[H])C([H])([H])C([H])([H])[C@]2([H])C1([H])[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C(C2=C1N1C(=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]13[H])N(C2=O)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C1=NN(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])[C@]([H])(N([H])C(=O)C([H])([H])OC([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])OC([H])([H])C(=O)N([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2(N([H])S(=O)(=O)C3=C(Cl)C(=C(Cl)C([H])=C3[H])C([H])([H])OC3=C4N=C(C([H])=C(C4=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC(F)(F)F)N1C(=O)N2C([H])([H])[C@@]([H])(C([H])([H])[C@@]2([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
CNC(=O)C1=CC=CC=C1NC1=C2N=C(NC2=NC=C1Br)C1=CC=C(F)C=C1
[H]OC1=C([H])C2=C(C([H])=C1Cl)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]2([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
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[H]\C(C1=C([H])C([H])=NC([H])=C1[H])=C1/C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
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CC(C)C1=CC=C(SC2=CN=C(O)C(=C2)C#N)C=C1
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[H]N([H])C(=O)C1(C2=C([H])C([H])=C([H])C(SC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])N3C([H])=C([H])N=C3C([H])([H])[H])=C2[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])[C@]1([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
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[H]N([H])C1=NC(=C([H])C(=N1)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
OB1OCC2=CC=C(OC3=CC(OCC4=CC=CC=C4)=CC=C3)C=C12
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[H]N(C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=NC(=NC2=C1C([H])=NN2C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(\C(\[H])=C(/[H])[C@@]([H])(O[H])C2=C(OC([H])([H])C3=C(Cl)C([H])=C([H])C([H])=C3Cl)C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
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[H][C@]12C[C@@](O)(CCN1CCC1=CC(OC)=CC=C21)C1=CC=C(Cl)C=C1
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[H]N([H])C1=C2C(SC([H])=C2C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C(C([H])=N1)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
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[H]N(C(=O)C1=C(N=C([H])N1C([H])([H])[H])N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(Cl)C(=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C(S1)C1=C([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2N=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C(=O)N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])N=C([H])C([H])=C2[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N=C1N(C(=O)\C(=C(\[H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)N1C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C2OC(=C([H])C(=O)C2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])C(O[H])=C(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
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[H]N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(C2=C([H])C3=C([H])N=C(N=C3C([H])=C2[H])N([H])C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C1=C2C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]\C(C1=C([H])N=C([H])S1)=C1/C(=O)C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(=O)N([H])C2=C([H])[C@@]3([H])C(=NC4=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])N5C([H])([H])C([H])([H])C([H])(O[H])C([H])([H])C5([H])[H])C([H])=C4C3=O)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
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[H]OC([H])([H])[C@@]1([H])C2=C([H])C([H])=C([H])C3=C2N(C2=C3C3=C(C(=O)N([H])C3=O)C3=C2N([H])C2=C3C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2N1[H])C(=N[H])N([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C1=C(C#N)C(OC([H])([H])C([H])([H])[H])=NC(N([H])C(=O)C([H])([H])[H])=C1[H]
[H]N(C1=C([H])C(Cl)=C([H])C([H])=C1F)C([H])([H])C([H])([H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C(Cl)=C(OC([H])([H])[H])C([H])=C2Cl)C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1([H])N([H])C(=S)N([H])C2=C([H])C([H])=C(C([H])=C12)C([H])([H])[H]
[H]OC1=C(C(=O)N([H])C([H])([H])[C@]2([H])N(C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C1Br
[H]N([H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C(\[H])=C1\C2=C(C([H])=C([H])C([H])=C2[H])N(C(=O)C2=C(Cl)C([H])=C(C([H])=C2[H])N2N=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1(F)F
COC1=CC=C(\C=C\C2=C(/C=C/C(O)=O)C(OC)=CC(OC)=C2)C=C1
[H]OP(=O)(O[H])OC([H])([H])[C@@]1([H])O[C@]([H])(N2C([H])=NC3=C(N=C(SC([H])([H])C([H])=C([H])[H])N=C23)N([H])C([H])([H])[H])C([H])([H])[C@]1([H])OP(=O)(O[H])O[H]
[H]OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])N([H])C(=S)N([H])[C@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C(/C1=C([H])C([H])=C([H])S1)C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC(=O)C(OC1=C([H])C([H])=C(SC([H])([H])C2=NC(=NS2)C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC2=NC([H])=NC(SC3=NN=C(S3)C([H])([H])[H])=C12)C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1N=C(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(SC1=C([H])C([H])=C(F)C([H])=C1[H])=C(C(=O)C2=O)C([H])(C([H])([H])[H])C([H])([H])[H]
CC(C)C(=O)NCC1=CC2=C(SC3=C(C[C@H]2N2CCN(C)CC2)C=CC=C3)C=C1
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1OC1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(Br)C([H])=C(C([H])=C1Br)C(=O)C1=C(OC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2N(C(=O)C(=C([H])C2=C1[H])C([H])([H])OC1=C([H])C(=C([H])C(F)=C1[H])C1(OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)[C@]2([H])OC3=C(C([H])=C(N([H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1[C@]([H])(SC([H])([H])[C@@]1([H])C(=O)C1=C([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C(F)C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C(S2)C2=NC([H])=C(S2)C2=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C(Cl)=C2[H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C3=C2N([H])C2=C3C3=C(C(=O)N([H])C3=O)C3=C2C([H])=C([H])C2=C3N(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)C(N1C(=O)C([H])([H])C([H])([H])C1=O)=C(Cl)C2=O
[H]N([H])C(=N\C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])\N([H])C1=C(I)C([H])=C([H])C([H])=C1[H]
[H]C1=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C([H])C(=C1[H])C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(F)(F)F