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[H]N(C([H])([H])C1=C([H])C([H])=C2OC([H])([H])C(=O)N([H])C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)C([H])([H])OC3=C([H])C([H])=C(F)C([H])=C23)C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])C([H])([H])N(C1=C([H])C(=C(C#N)C([H])=C1[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C2C3=C4C([H])=C([H])C([H])=C([H])N4N=C3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C1=O
[H]OC1=C(N([H])C2=C(N([H])[C@@]([H])(C3=C([H])C([H])=C(O3)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C2=O)C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])=C1[H])C([H])([H])N1C2=C([H])C(OC3([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])C([H])=C2N=C1[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]N(\N=C1\C2=C(N([H])C3=C2C([H])=C(F)C([H])=C3[H])C(=O)N([H])C([H])([H])C1([H])[H])C1=C([H])N=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C(=O)C2=C(C([H])=C(N2N=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1Cl)C([H])([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])=C([H])[C@@]23C4=C(C(OC([H])([H])[H])=C([H])C([H])=C4C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]3([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])C([H])([H])C2([H])[H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=NC(=C([H])C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1C#N
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@](N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])(C(=O)O[C@@]1([H])C([H])([H])[N@+]2(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H])C([H])([H])[H]
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[H]C1=C([H])N(N=N1)C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(OC([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(=N\OC([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H])\C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(F)C(Cl)=C1[H])C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C([H])C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])S(=O)(=O)C([H])([H])[H])=C12
[H]N=C(N([H])C1=C([H])C(Br)=C([H])C([H])=C1[H])N(C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])S1
[H]N1C(=O)S[C@@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C(=O)N(C([H])=C2[H])C([H])([H])[H])[C@@]([H])(C(=O)N(C([H])([H])C2=C([H])N(C3=C2C(F)=C([H])C([H])=C3[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C2([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1N=C([H])C2=C1N=C(N1N=C(N=C21)C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=C1C([H])([H])N(C(=O)C1=C([H])C(=C([H])C([H])=C1O[C@@]([H])(C([H])([H])[H])C(F)(F)F)S(=O)(=O)C([H])([H])[H])C2([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
C(CC[N]1=CC2=C(C=C1)C1=CC=CC=C1N2)C[N]1=CC2=C(C=C1)C1=CC=CC=C1N2
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[H]OC1=C([H])C([H])=C(N2C([H])=C(C(=O)N([H])[H])C(=O)C3=C([H])C([H])=C(C([H])=C23)C2=C([H])C([H])=NC([H])=C2[H])C(=C1[H])C([H])([H])[H]
[H]N(N([H])C(=O)C1=C([H])N=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
CS(=O)(=O)NC1=C2N=C(C=C(O)C2=CC=C1)C(=O)NC1=CC=CC=C1C#N
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C3=C(C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N1C(=O)N2N(C1=O)[C@@]([H])(C([H])=C([H])C2([H])[H])C(=O)N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1([H])[H])C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(N([H])C([H])([H])[C@]2([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3Cl)C([H])([H])C([H])([H])C2([H])[H])=C([H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N(C(=O)C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C(=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC(C)(CC(O)(CC1=CC2=CC=NC=C2N1)C(F)(F)F)C1=CC(Cl)=CC2=C1OCC2
[H]N(C(=O)C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C(N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C(=C([H])C([H])=C3N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])[N+]([O-])=O)C([H])([H])C2([H])[H])=C(F)C([H])=C1C(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC2=NC([H])=NC(N([H])C3=C([H])C([H])=C(OC([H])([H])C4=C([H])C(F)=C([H])C([H])=C4[H])C(Cl)=C3[H])=C2[H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC([H])=C(F)S1
[H]N([H])C1=NOC2=C([H])C([H])=C([H])C(=C12)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=NN3C([H])=C([H])C(=O)N=C3C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])OC1=C([H])C([H])=C2N=C(SC2=C1[H])S(=O)(=O)N([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=NC(=C([H])O1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(=NC(=N1)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)[C@@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C1=NC(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])N([H])[C@]1(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C(=O)N([H])[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC(=O)C([H])([H])N(C1=C(F)C(OC2=C([H])C(=C([H])C([H])=C2[H])C2=NC([H])([H])C([H])([H])N2C([H])([H])[H])=NC(OC2=C(O[H])C([H])=C([H])C(=C2[H])C(=N[H])N([H])[H])=C1F)C([H])([H])[H]
[H]O[C@]([H])(C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C(=C(OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H])S([O-])(=O)=O
[H]N(C([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])C2=C([H])N([H])N=C2C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])OC1=C([H])C([H])=C(SC2=C(N([H])[H])C([H])=C(F)C([H])=C2[H])C(=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=C(C([H])=C1[H])[C@@]1([H])SC([H])([H])C(=O)N1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C(=NC(=O)C1=C(OC(=N1)C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])[H])N([H])[H]
[H]N1C([H])=NC2=C1C(=O)N(C(=O)N2C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)[C@@]2([H])N3C(=O)C([H])([H])N(C([H])([H])[C@]3([H])C([H])([H])C2([H])[H])S(=O)(=O)C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C(Br)=C1[H]
[H]OC(=O)[C@@]1([H])N(C([H])([H])C(=O)C2=C([H])C([H])=C3N([H])C4=C(C3=C2[H])C2=C(C(=O)N([H])C2=O)C2=C4C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C2=C1N=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=NN=C(O2)C2=C([H])C(Cl)=C([H])C(F)=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])N(C(=O)[C@@]1(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C1([H])[H])C([H])([H])[H]
N[C@@H](CCCNC(=N)N[N+]([O-])=O)C(=O)N[C@@H](CC[NH3+])C(N)=O
[H]N(C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C1=C2N=C([H])N(C2=NC(=N1)C1=C([H])C([H])=C(S1)C(=O)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C(=O)O\N=C(\C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=NOC(=N1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]C1=NN(C(=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C1/C(=O)N([H])C2=C1C(Cl)=C(C([H])=C2[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C(=O)[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N1N=C(N(C1=S)C([H])([H])C([H])([H])[H])C([H])([H])SC1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C(=N1)N([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])N12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=N1)C([H])([H])[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C(N=C3[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NN(C([H])=C1C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C(=O)N(C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(SC3=C([H])C4=C(OC([H])([H])C([H])([H])O4)C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1N(C(=O)[C@]([H])(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1=O
[H]N(C(=O)C([H])([H])[H])[C@]1([H])C2=C([H])C(=O)C(SC([H])([H])[H])=C([H])C([H])=C2C2=C(C([H])=C(OC(=O)C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])[C@@]([H])(N([H])[H])C(=O)[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])[C@]12[H]
[H]O[C@@]([H])(C([H])([H])[H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C1=NN(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])\N=C(/[H])C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C(N([H])C(=O)C2(C([H])([H])C3=NC(=NO3)C3=NC([H])=C(O[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])OC([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC(Cl)=C1C1=C([H])C([H])=C([H])C(Br)=C1[H])N([H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2(N([H])S(=O)(=O)C3=C(Cl)C(=C(Cl)C([H])=C3[H])C([H])([H])OC3=C4N=C(C([H])=C(C4=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NN(C2=C1C([H])=NC(=N2)N([H])C1=C([H])C(F)=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C(OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])OC2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C(\[H])=C(/[H])C2=C([H])N=C([H])C(C#N)=C2N([H])C2=C(C3=C(N([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(Br)=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C([H])([H])[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C(=O)C2=C([H])C(C3=C([H])N=C([H])O3)=C(OC([H])([H])[H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(C1=C(N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C12)C(C(=O)OC([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2[H])C(=N1)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(C1=C([H])C(C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=C(C([H])=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C2/OC(=O)N(C2=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1Br
[H]N([H])C1=NC([H])=C([H])C(=N1)C(\[H])=C(/[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N1C2=C(C([H])=C1C1=C([H])C3=C(N([H])C1=O)C([H])=C([H])C([H])=C3[H])C([H])=C(C([H])=C2[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(Cl)C([H])=NC([H])=C1Cl)C([H])([H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@]([H])(OC1=NC(Cl)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]C1=C([H])C2=C(C(=NC2([H])[H])C2=C([H])C(=NC([H])=C2[H])C(=O)N2C([H])([H])[C@@]3([H])OC([H])([H])[C@]2([H])C3([H])[H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=N1
[H]C1=NN(C2=C([H])C([H])=C(C([H])=C12)N1C([H])=C([H])C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC(=NC(=N1)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=NC2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H]
CC1=CC=C(C(C)=C1)S(=O)(=O)N1CCC(CC1)C(=O)NC1CC1
[H]N1C(=C([H])C2=C1C([H])=C([H])C(OC1=NC([H])=NN3C([H])=C(OC([H])([H])C([H])([H])C4([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C4([H])[H])C(=C13)C([H])([H])[H])=C2F)C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C#N
[H]N(C([H])([H])C1=C([H])C([H])=NN1[H])[C@@]1([H])C([H])([H])C(=O)N2C([H])([H])[C@]([H])(O[C@@]([H])(C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C(F)C([H])=C3[H])[C@]12[H]
[H]N(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=C(/[H])C([H])=C1C([H])=C([H])C(=O)C([H])=C1[H])\C1=C([H])C([H])=C([H])C([H])=C1F
[H]N([H])C1=C(N(C(=O)C([H])([H])SC2=NC([H])=NC3=C2C([H])=C(S3)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)N([H])C(=O)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C([H])C(OC3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]OC(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]2(C3=C(OC4=C(C([H])=C([H])C([H])=C4[H])C2([H])[H])C([H])=C([H])C([H])=C3[H])C1([H])[H]
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[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)C1=C(C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2F)C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])SC1([H])[H]
[H]N(C(=O)C1=C([H])/C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C\1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[S@@](=O)C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C([H])([H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC1=NC([H])=C(Cl)C2=C([H])C([H])=C(C([H])=C12)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])N([H])[H]
NS(=O)(=O)C1=CC=C(C=C1)N1N=C(C=C1C1=CC=C(C=C1)[N](\O)=N/O)C(F)(F)F
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C2C([H])=C([H])C([H])=NC2=C([H])C([H])=C1[H])C1=C(C2=NC([H])=NN2[H])C(C#N)=C([H])S1
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
CCC1=NC2=C(N1[C@H]1CCC3=C1C=CC(=C3)C1=CC=CC=C1C1=NN=NN1)C(=O)N(CC(=O)OCC1=CC=CC=C1)C=C2
[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C([H])([H])SC1=NN=C(N1C([H])([H])C1=C([H])C([H])=C([H])O1)C([H])([H])SC1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=O)\C(S1)=C(\C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
COC1=CC2=C(C=C1)N=C(C(F)F)N2C1=NC(=NC(=N1)N1CCOCC1)N1CCOCC1
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C1=C(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])C([H])([H])C3=C12)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C(Br)C(=NN1C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C(=O)N(C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C2=NC([H])=C([H])S2)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1([H])[H]
[H]C([H])([H])[C@]1([H])C([H])([H])C2=C(SC(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=O)C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(Br)=C(N([H])S(=O)(=O)C2=C(F)C(F)=C(F)C(F)=C2F)C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=N[C@@]2([H])N=C([H])N=C(N([H])C3=C([H])C4=C(C([H])=C3[H])N(N=C4[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2=C1C([H])([H])C([H])([H])[H]
[H]C1=C([H])N2C(=C1[H])[C@]([H])(N(C(=O)C([H])([H])N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C2C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])S1)[C@@]([H])(O[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(C(=O)C2=C(N([H])S(=O)(=O)C3=C(Cl)C([H])=C(Cl)C([H])=C3[H])C([H])=C([H])C([H])=C2[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C(OC([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(C1=NC(=NC2=C1C([H])=C(N2C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])=NC2=C1C([H])=NC([H])=C2[H])C1=C(Cl)C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1(C(=O)N([H])C2(C([H])([H])O[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(I)C([H])=C(\C([H])=C(/[H])C(=O)C([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N1N=C(C2=NC([H])=C([H])S2)\C(=C(/[H])C2=C([H])N(C3=C2C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C3[H])C([H])([H])[H])C1=O
[H]OC1=C(C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=NC(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])C([H])(C(=N\OC([H])([H])[H])\C4=C([H])C([H])=C(Br)C([H])=C4[H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=NN([H])C2=C1C([H])([H])[C@]1([H])[C@@]2([H])[C@]1([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C2C([H])=C(N([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C3=C(S2)C([H])=C([H])C([H])=C3F)C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C(=N1)C1=C(Cl)C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C([H])C(=C([H])C2=C1C([H])=C([H])C(=O)N2C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NN(N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N([H])S(=O)(=O)C1=NN2C(S1)=NC(=C2C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C1(C([H])([H])OC2=C([H])C3=C([H])C([H])=C(C([H])=C3C([H])=C2[H])[C@@]([H])(N2C([H])=NC([H])=C2[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])(OC2=C(OC([H])([H])C(F)(F)F)C([H])=C([H])C(=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)O[C@@]1([H])[C@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(Br)=C1OC([H])([H])[H])[C@@]1([H])C([H])([H])C2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]O[C@]([H])(C([H])([H])C(\[H])=C(/[H])[C@@]1([H])[C@]([H])(O[H])C([H])([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C1(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C2N=C(N=C2N(C(=N1)N([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])N([H])[H]
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[H]OC1=NN=C(SC2=NC([H])=C(S2)[N+]([O-])=O)N1C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])(C([H])([H])C([H])([H])N2C3([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])[C@@]([H])(N2C4=C(N=C2C([H])([H])[H])C([H])=C([H])C([H])=C4[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]OC1=NN=C(O1)C1=C([H])C(=C(O[H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(S1)C([H])=C(C([H])=C2[H])C1=C([H])C([H])=NN1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)[C@]1(C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]N(C1=C([H])C([H])=C(F)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])S[C@@]([H])(C2([H])[H])[C@@]1([H])N([H])[H]
CN1C=C[N+](CC(O)(P(O)(O)=O)P(O)([O-])=O)=C1
[H]OC(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C(C([H])=C1F)C(=O)N1C([H])([H])C([H])([H])C([H])(N(C2([H])C([H])([H])C2([H])[H])S(=O)(=O)C2=C(F)C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(F)C2=C1C([H])([H])C(=O)N2[H]
[H]N(C1=NC(=C([H])C([H])=N1)N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(Cl)O3)=C2[H])C([H])=C1[H]
[H]OC1=C2C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C2OC([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C2=C1[H]
[H]N1N=C(N(C1=S)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])S(=O)(=O)C1=NN(\C(S1)=N\C(=O)C1=C(F)C(F)=C([H])C(F)=C1F)C([H])([H])[H]
[H]C1=C([H])C(=C([H])O1)C1=C([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])N2C(=NC3=C([H])C([H])=C(C([H])=C3C2=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C(N=C(S1)N([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C(N2C([H])=C([H])C(C3=C([H])C4=C(N(C([H])=C4[H])C([H])([H])C4([H])C([H])([H])C4([H])[H])C(Cl)=C3[H])=C(C#N)C2=N1)C([H])([H])C(F)(F)F
[H]OC(=O)C([H])([H])C1=C(N(C2=C([H])C([H])=C(F)C([H])=C12)S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=NC2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)[C@@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=NC(OC2([H])C([H])([H])C([H])([H])N(C3=C(Cl)C([H])=C([H])C([H])=N3)C([H])([H])C2([H])[H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])O[N+]([O-])=O)C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])[C@]([H])(C1=O)C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]O\C(OC([H])([H])C([H])([H])[H])=C1\C(=NC(=C(C(=O)OC([H])([H])[H])[C@]1([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=NC([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C(N=C(O1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]\C(\C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C(\[H])C1=NC2=C(N1C([H])([H])C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C#CC([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C([H])C([H])=C3[H])C2=C1[H]
[H]C1=C(N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])C(OC([H])([H])[H])=C(SC([H])([H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C1=O
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(\N=C(/[H])C2=C([H])C(=C([H])C([H])=C2[H])[N+]([O-])=O)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(N=C2N1[H])C1=C([H])N([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C3OC(=C(C(=O)C3=C2[H])C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C(OC([H])([H])[H])C(Br)=C1[H])C([H])([H])[C@]1([H])C(=C([H])[H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=NN=C(O1)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C(C(O[H])=NC2=C([H])C(Cl)=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])C([H])(N([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=[N+]1C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C(=O)C1=NC(I)=C(N=C1N([H])[H])N([H])[H]
[H]N([H])C(C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])=NC2=C(C([H])=C(N=C2[H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1=O
[H]N(C1=NN=C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)N1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=CC(=C(C(=O)N1CC1=CC=CC=C1)C1=CC=C(C[C@H](NC(=O)C2=C(Cl)C=CC=C2Cl)C(O)=O)C=C1)C(F)(F)F
[H]C1=C([H])C(=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(=O)C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C2N(C(=O)C(=O)C2=C([H])C([H])=C1[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]N(C(=O)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C1([H])[H])[C@]([H])(N([H])C(=O)[C@@]1([H])N2C(=O)C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C(=O)OC([H])([H])[H]
[H]N(OC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1N=C([H])C(OC2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)=C1[H])C1=NC([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N=C(O1)C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C(=O)N([H])C2=NC([H])=C([H])C(=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])([H])C(=O)O[C@@]([H])(C([H])([H])O[C@]1([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])[N+]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
FC(F)(F)OC1=CC=C(NC(=O)NC2CCN(CC2)C(=O)C2CC2)C=C1
[H]N(C1=NC(=O)C2(O1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])[C@@]([H])(N(C([H])([H])[C@@]1([H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=O)C([H])=C(OC2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N2N=C(OC([H])([H])[H])C(N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=N3)C([H])([H])C([H])([H])C([H])([H])F)=C2S1)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]N1N=C(C2=C([H])C([H])=C(OC([H])([H])[H])N3N=C([H])C([H])=C23)C(C1=O)(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])N1N(C(=O)C(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
COC1=C2C(CCC(O)=O)=CN(C)C2=C(C=C1)C1=NOC(=N1)C1=CC(Cl)=C(OC(C)C)C=C1
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])=NC(=C2C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C([H])C(=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])[C@]([H])(C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C2=C([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])[C@]5([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[C@]45C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])N1C(=NC(=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(F)C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=O)OC2=C1C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C2[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C#N
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(Cl)C([H])=C2N=C([H])C(=C(OC([H])([H])C([H])([H])[C@]3([H])N([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C2=C1[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C(C([H])=C(C([H])=C3[H])[N+]([O-])=O)C([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C([H])=NC([H])=C2[H])=N1
[H]N1C([H])=NC([H])=C1\C([H])=C1\C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[C@]1(O[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])[C@@]([H])(N(C2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])N=C(C#N)C([H])=C1[H]
[H]N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@@]1([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=NN=C(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])S1
[H]N([H])C(=O)C(=O)[C@]([H])(N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C3=C(N=C2[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])N(C([H])([H])C([H])([H])[H])S(=O)(=O)C2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C2C1([H])[H])[C@]([H])(C(=O)C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C(C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1C1=C(O[H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)[C@@]([H])(N([H])C1=C(C([H])=NC([H])=N1)C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
CCOC(=O)C1=CC=CC(=C1)B(O)O
[H]N1C(=NC([H])([H])C1([H])[H])C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C2=C([H])N([H])N=C2C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(F)=C2[H])N1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
ON(=O)C1=C2NN=C(Br)C2=CC=C1
[H]N([H])C([H])(N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(S1)[C@]1([H])C([H])([H])[C@@]1([H])C(=O)N([H])C1=NC([H])([H])C([H])([H])C([H])([H])N1[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N1C([H])([H])C([H])([H])N2[C@@]([H])(C([H])([H])OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1N1C(Cl)=C(Cl)N=C(Cl)C1=O)C([H])([H])[H]
[H]OC(=O)[C@@](N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@]1([H])N(C2=NC3=C(N=C([H])N3C([H])(C([H])([H])[H])C([H])([H])[H])C(=N2)N([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@]1([H])C(=O)N(C2=C([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])[C@@]2(C(=O)OC([H])([H])[H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]ON([H])C1=C(N=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)OC([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N1C(=O)N(C([H])([H])C([H])([H])C([H])([H])C2=NC3=C(C([H])=C2[H])C([H])([H])C([H])([H])C(=O)N3[H])C([H])([H])C1([H])[H])C1=C([H])N=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C(F)=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(\[H])=C(/[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC1=C2N([H])C(=O)C([H])([H])C3=C(N([H])C4=C3C([H])=C(Br)C([H])=C4[H])C2=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(S1)[C@@]([H])(N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H])C1=NN=NN1C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)C1([H])C([H])([H])C([H])([H])N(C2=C([H])C(F)=C(C#N)C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=NC([H])=C2[H])C([H])=C1O[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(\N=C(/[H])[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])\C(\[H])=C(/[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=C2C(=C([H])S1)C(=NN(C2=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])C([H])([H])[H]
[O-][N+](=O)C1=CC=C(C=C1)[C@@H]1CC(=NN1)C1=C2C=CC=CC2=CC2=CC=CC=C12
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])OC(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F)C(=O)N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])S(=O)(=O)C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1[C@]2([H])C3=C(N(C4=C([H])C([H])=C(C([H])=C34)S(=O)(=O)C3=NN(C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1SC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]N1C([H])([H])C2=C(N(C([H])=C2C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O\N=C(/N([H])[H])C1=C([H])C2=C(N([H])C3=NC([H])=C([H])C([H])=N3)C([H])=C(C([H])=C2C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])[H]
[H]C1=C([H])C2=C(O1)C([H])=C([H])N=C2N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C2C([H])=C([H])C([H])=NN2N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1F)C([H])([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])C([H])([H])C(=O)[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)[C@@]([H])(O[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1N([H])C1=C(N([H])[C@@]([H])(C2=C([H])C(C#N)=C([H])C(F)=C2[H])C([H])([H])C([H])([H])[H])C(=O)C1=O)C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]N(C(=O)N1C([H])([H])C([H])(N([H])C2=NC([H])=C(Cl)C(=N2)C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1([H])C([H])([H])C([H])(OC2([H])C([H])([H])C3([H])OC4([H])\C([H])=C([H])/C([H])([H])C5(OC6([H])C([H])([H])C7([H])OC8([H])C([H])(OC9([H])C([H])([H])C%10(OC%11([H])C(=C([H])C(=O)OC%11([H])C([H])([H])C%10([H])OC9([H])C([H])([H])C8([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C7(OC6(C([H])([H])[H])C([H])([H])C5([H])OC4([H])C([H])([H])C3([H])OC12C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=C([H])[H])C([H])=O
[H]N(C1=NC([H])=C(C2=NN=C(O2)C2([H])C([H])([H])C2([H])[H])C(=N1)N([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)N3C(=C(C2=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NO[C@@](C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])(C([H])([H])OC([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=NC(=NO1)C1=C([H])N(N=N1)C([H])([H])C1=C([H])C(Br)=C(Br)C(Br)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(N2N=C(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(Cl)=C2C([H])([H])[H])C(=C1[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]OC(=O)C1=C([H])C(OC([H])([H])[H])=C(C([H])=C2C([H])([H])C([H])([H])N(C(=O)C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])OC2=C([H])C([H])=C3C(=C2[H])C([H])=C(C([H])=C3C2=C([H])C([H])=C([H])C([H])=C2[H])C2=NN=NN2C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(C([H])=NC2=NC(Br)=C([H])C([H])=C12)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(F)=N1)C([H])([H])N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@@]([H])(O[C@]2([H])[C@]([H])(C(=O)O[C@]([H])(C([H])([H])C([H])([H])[H])[C@](O[H])(C([H])([H])[H])[C@]([H])(O[H])[C@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])[C@](OC([H])([H])[H])(C([H])([H])[H])[C@]([H])(O[C@]3([H])O[C@]([H])(C([H])([H])[H])C([H])([H])[C@]4([H])N(\C(O[C@@]34[H])=N/C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[H])[C@@]2([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1(OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)N1N=C(N=C1SC([H])([H])[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2O1
[H]\C(=C(\[H])[N+]([O-])=O)C1=C([H])C2=C(C([H])=C1[H])N(C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C3=C(C([H])=C2C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C3=O
[H]C1=C([H])C([H])=C2N(C3=C([H])C([H])=C([H])C([H])=C3SC2=C1[H])C([H])([H])[C@@]1([H])C([H])([H])[N@+]2([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1(N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(N2C(Cl)=C(Cl)C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C1([H])[H])C([H])([H])OC(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C2N=C([H])N(C2=C2N=C(N(C2=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C([H])C(=O)O2)C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)[C@@]([H])(N1C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C(N=C(S1)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(Br)C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C#N
[H]C1=C(OC([H])([H])[H])C(=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C(F)(F)F
[H]N1C(=O)C([H])=C([H])C2=C1C([H])([H])[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]2(\N=C(/[H])\C(\[H])=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])\C1=C(/[H])C([H])([H])[H]
[H]N1C(=O)N([H])[C@]([H])(C1=O)C1=C([H])C(Cl)=C([H])C([H])=C1SC([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC(=O)C1=C([H])C(\N=N\[C@@]2([H])N(C(=NC2=O)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=NC([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C2=NON=C12)[N+]([O-])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])N(C1=NS(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C2C([H])=C([H])C(=C([H])C2=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[N+]([O-])=O
[H]C1=C([H])C2=C([H])C(=C([H])C([H])=C2N1C([H])([H])[H])[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])C([H])([H])[H]
ClC1=C(NCN2N=C(OC2=S)C2=NC3=CC=CC=C3C=C2)C=CC=C1
[H]N1C(=O)S[C@@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])O\N=C(\C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)N(C2=NC([H])=NC(OC3([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1F)S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C2=C([H])C([H])=C([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(=C23)C([H])([H])C1([H])[H]
[H]OC(=O)C1=C2N(C(SC([H])([H])C([H])([H])[H])=NC2=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NOC(O[H])=N1
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N2C(=NC(Cl)=C2[C@@]([H])(N2C(=O)C([H])([H])C([H])([H])C2=O)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N1N=C(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(\C([H])=C2\N(\C(=N\C([H])([H])[H])N([H])C2=O)C([H])([H])[H])C2=C1C([H])=C(Br)C([H])=C2[H]
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[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N([C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])SC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C(Cl)C([H])=C2C([H])=C1[H]
[H]N([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)C([H])=C([H])C2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC(=O)N([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C([H])C(Cl)=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C([H])([H])C1(C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(C(=NC(=N1)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])N([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NN([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1C(=O)O[H])C([H])([H])C([H])([H])S[H]
[H]N(C(=O)C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(C2=C3N=C(N=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C4([H])C([H])([H])C4([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C(OC([H])([H])[H])=NC(OC([H])([H])[H])=N1
[H]C1=C([H])N2C(=C1[H])C(OC(=O)C([H])([H])C([H])([H])[H])=C(SC1=C([H])C([H])=C(Cl)C([H])=C21)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N/C(=O)[C@@]([H])([3H])C([H])([H])[3H])\N([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])([H])C1=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=NN(C2=NC([H])=NC(OC3([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=C2N([H])C([H])([H])C3=C(OC2=NC([H])=N1)C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C1=C(F)C([H])=C([H])C(Cl)=C1[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C(F)=C2[H])C(F)=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(N=C1[H])N1C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(O[C@@]([H])(C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C(F)C([H])=C3[H])[C@]2([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C(=O)C(=O)C2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)C1=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N2C(=S)S\C(=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2=O)=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])SC1=NC2=C(N1C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=NC2=C(S1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])N1C2=C(C([H])=C(Br)C([H])=C2[H])C([H])([H])N([C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(S1)C1=C([H])C(F)=C([H])C([H])=C1[H])[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])[C@@]11C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NN([H])N=N1
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@@]1(C(=O)OC([H])([H])[H])C([H])([H])[C@@]3([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]1([H])[C@]([H])(C([H])([H])C([H])([H])OC([H])([H])[H])C3([H])[H]
[H]OC1=NC(=C(C2=C([H])C([H])=C3N([H])C(=NC3=C12)N([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])OC(=O)N2C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C(OC([H])([H])[H])C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=C([H])[N+]([O-])=C4C(F)(F)F)C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H]
[H]N(C(=O)C1(C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])P(=O)(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(F)(F)F
[H]N(C(=O)C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1N=NN=C1[H]
[H]O[C@@]1(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C3=C([H])C([H])=C([H])C(=C3[H])C(F)(F)F)C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])SC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(C2=NN=C(N2C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2Cl)=C(C([H])=C1[H])C(F)(F)F
[H]OC(=O)C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C(N=C2C([H])=C([H])C([H])=C([H])N12)C1=C([H])C([H])=C([H])C(=C1[H])C1=NC2=C(N1[H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
FC(F)(F)C1=NC(SC2=NN3C(C=C2)=NN=C3C2=CN=CS2)=NC=C1
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C(F)C(C#N)=C3[H])C([H])([H])[C@]12[H])C1=C([H])C(=C(F)C([H])=C1[H])C(F)(F)F
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=N1)[C@]1(O[C@]2([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=NC([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C(=O)N(C([H])([H])C2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N(C(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])N(C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])[C@]([H])(C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])[H]
CC(=O)N[C@@H](CC1=CC(F)=CC(F)=C1)[C@H](O)CNC1(CCCCC1)C1=CC(NS(C)(=O)=O)=CC(=C1)C(C)(C)C
[H]O\C(=C(\C#N)C(=O)N([H])C1=C([H])C([H])=C(C2=C([H])C([H])=C(F)N=C2[H])C(=C1[H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])[H]
CCOC(=O)C1=C(N2N=C(C=C(C2=C1C(=O)OCC)C1=CC=CC=C1)N1CCOCC1)C1=CC(OC)=CC=C1
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])SC1=NN=C(S1)C([H])([H])SC1=NN2C(=N1)N=C(C([H])=C2C([H])([H])[H])C([H])([H])[H]
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2NC1CC1
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)N(C2=C([H])C(OC([H])([H])[H])=NC([H])=N2)C2(C1=O)C([H])([H])C([H])([H])N(C([H])([H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C1=NC(=C([H])C(=N1)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2OC([H])([H])C([H])([H])[H])C([H])([H])C2=NC([H])=C(S2)C2=C([H])C([H])=C([H])S2)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N1N=NN=C1C1=C([H])C(Cl)=C([H])C(=C1[H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N([H])C1=C(\C([H])=N\OC([H])([H])[H])C(=NC([H])=N1)N([H])C1=C([H])C(Cl)=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C2C(SC([H])=C2C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2OC([H])([H])[H])=N1
[H]N(C(=O)[C@@]([H])(N1C(=O)[C@]([H])(N(C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])[C@]1(N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C2=C1C1=C([H])C([H])=C(C([H])=C1C2=O)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])=C([H])C1=C2OC(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]([H])(C(=O)O[C@]1([H])C([H])([H])[C@@]2([H])[C@@]3([H])O[C@@]3([H])[C@@]([H])(C1([H])[H])[N@+]2(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(SC([H])=C1C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C(N([H])C(=O)C3=C([H])C([H])=C([H])C(=C3[H])C(F)(F)F)=C([H])C([H])=C2C([H])([H])[H])C([H])=NN1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(C([H])=N1)C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NOC(=C1[H])C1=C([H])C([H])=C([H])S1)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(N([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])S(=O)(=O)C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C(=C(O[H])C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C(ON=C1C([H])([H])[H])C1=C(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])[C@]2([H])S[C@@]1([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N(N=C(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H])C1=NC(=O)C([H])([H])S1
[H]OC(=O)C1=C([H])C([H])=C(\C([H])=C(\C(\[H])=C(/[H])C2=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])/C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])N2C(=C1[H])C(=O)[C@](OC1=C([H])C([H])=C([H])C([H])=C21)(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])[H]
[H]N([H])C(C(=O)N([H])[C@@]([H])(C1=NN(N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C#N)C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])SC([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])[C@]([H])(N([H])S(=O)(=O)C2=C(C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]N([H])C(=O)C1=C2N([H])C(=O)N(C2=NC(=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])N=C12)C1=C([H])C([H])=C2N=C([H])C3=C(N(C(=O)C([H])=C3[H])C3=C([H])C(=C(F)C([H])=C3[H])C([H])([H])[H])C2=C1[H]
[H]N1N2C(N=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])=NC(=C(C2=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C([H])([H])P(=O)(O[H])O[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C(F)C([H])=C1C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]O[C@@]1(C#CC([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])[C@@]3([H])C(=C4C(=C([H])C(=O)C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])[C@@]([H])(C3=C([H])C([H])=C(C([H])=C3[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]12C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]SC([H])([H])[C@]1(C(=O)N([H])[C@]([H])(C(=O)N([H])C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)O[C@@]([H])(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=C2N1C([H])([H])C([H])([H])N(C2=O)C([H])([H])C([H])([H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]