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[H]N([H])C([H])([H])C(F)(F)C([H])([H])OC1=C([H])C([H])=C([H])C2=C([H])C([H])=C(N=C12)C1=NN=C2C([H])=C([H])C([H])=C([H])N12
[H]N(C(=O)C1=C(N=C([H])C([H])=N1)N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(OC2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C([H])C(O[H])=C(C([H])=C1C1=C(N([H])C(=O)[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C2([H])[H])C(=NO1)C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C([H])=C2N1[H])C([H])([H])C(=O)N(C([H])([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C2=C(N([H])C3=NC([H])=NC(=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N(C(=O)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]12[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=NOC(=N1)C([H])([H])OC1=C([H])C(Cl)=C(Cl)C([H])=C1Cl
[H]O[C@](C1=C([H])C([H])=C([H])N1C([H])([H])C([H])([H])OC([H])([H])[H])(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]ON([H])C(=O)C([H])([H])C1(N([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])C3=C4C([H])=C([H])C([H])=C([H])C4=NC(=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C(C#C[H])(C([H])([H])[H])C([H])([H])[H]
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[H]O[C@@]1([H])C([H])([H])[C@]([H])(O[C@@]2([H])C([H])([H])[C@]3([H])O[C@@]4([H])C([H])([H])C([H])([H])C([H])([H])[C@]5([H])O[C@@]6([H])C([H])([H])\C([H])=C([H])/C([H])([H])[C@]7([H])O[C@]8([H])C([H])([H])[C@]9([H])O[C@@]%10([H])C([H])([H])C(=O)O[C@@]%10([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]9(O[C@@]8([H])C([H])([H])[C@]([H])(C([H])([H])[H])[C@]7([H])O[C@]6([H])C([H])([H])\C([H])=C([H])/[C@@]5([H])O[C@@]4(C([H])([H])[H])C([H])([H])[C@]3([H])O[C@@]12[H])C([H])([H])[H])C([H])([H])C(=C([H])[H])C([H])=O
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])N=C([H])C([H])=C1N([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[C@]12C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]\C(=C(\[H])[N+]([O-])=O)C1=C([H])C([H])=C(OC(=O)C([H])([H])C([H])([H])C([H])([H])C(=O)OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=C(C([H])=NC2=C(OC([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])C([H])=C([H])C([H])=C12)C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C2C([H])=C([H])C([H])=C([H])C2=C1\N=N\C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C(O[H])=C1O[H])S(=O)(=O)O[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1C([H])([H])OC([H])(C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C([H])O1
[H]C1=C([H])C2=C(C([H])=C1[H])C(=NC1=C([H])C(=C([H])C([H])=C1S2)C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]2([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=NN=C1[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
CN(C)CCCOC1=NC2=C(CCN(C)C2)S1
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(N3C(=O)C4=C(C3=O)C3=C([H])C(F)=C([H])C([H])=C3C([H])=C4[H])C([H])([H])C2([H])[H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]C1=C(C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C(F)=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1C1=C([H])N=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)N1C([H])([H])C([H])([H])C([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NO[C@]([H])(C([H])([H])C(=O)OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C3=C(O2)C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C3([H])[H])C(=N1)N([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C(I)=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])[H]
[H]C1=C(C(=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])[H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
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[H]C1=C2C([H])([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])C(=O)[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])SC([H])([H])[H])C([H])([H])C([H])([H])C1=O
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[H]N=C(N([H])[H])N([H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N([H])C1=C([H])C(=C([H])C([H])=C1Cl)N1N=NN=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1Cl)C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=NO[C@@]([H])(C([H])([H])C([H])([H])N([H])C2=NC([H])=C([H])N2[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C2(C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])N(N=C1[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H])C1=C([H])SC([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(OC2=C(N([H])C(=O)C3=NC([H])=C([H])C(=C3[H])[N+]([O-])=O)C([H])=C(F)C([H])=C2[H])C([H])=C1C(=O)O[H]
[H]N(C(=S)N1N([H])C2=C(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@@]1([H])C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
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[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C(I)=C([H])C(Br)=C1[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])=C([H])C1=C2C([H])=NN1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])N1[H]
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[H]N([H])C1=C(SC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
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[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=NN([H])C(=N1)N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]N(C(=O)C([H])([H])SC1=NC(C2=C([H])C([H])=C([H])O2)=C(N=N1)C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NOC3=C2C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C(N(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@@]2([H])OC([H])([H])C(=O)[C@@]12[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C(N(C3=C([H])C([H])=C(Cl)C([H])=C23)C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(SC(=C2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])OC2=C(C([H])=C(Br)C([H])=C2[H])C([H])([H])OC([H])([H])[H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C(N=C(N=C1[H])C([H])([H])[H])N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
C[C@H]([C@H](NC(=O)C(C)(C)N)C(=O)N1CCC[C@H]1C1=NC2=C(N1)C=C(Cl)C(Cl)=C2)C1=CC=CC=C1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C1=C2C(=C([H])C(=C1C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C2([H])[H]
[H]SC([H])([H])[C@]([H])(N([H])[H])C([H])([H])N([H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N1C2=C(N([H])C(=N2)C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=NN2C([H])([H])[H])C2=N[C@@]([H])(C([H])([H])[H])C([H])([H])N2C1=O
[H]N([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C1=NC(=NC([H])=C1Cl)N([H])C1=C([H])N(N=C1[H])C([H])([H])[H]
[H]N(N1C([H])=C([H])N=C1C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C2C(=NC(=N1)C([H])([H])[H])N(N=C2C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])[H]
CC(C)=CCN1C=C(CC(N)=O)C2=CC(=CC=C12)C1=CC(C)=CC=C1
[H]N(C(=O)C1=C([H])C([H])=C([H])N2N=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C([H])C2=C1C([H])=NC1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C21)C1=C([H])C(OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])=C([H])N=C1[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(C([H])=N1)C(=O)C([H])([H])[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C1([H])[H])C2([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C([H])C([H])=C([H])C(C3=NC4=C([H])C(F)=C(O[H])C([H])=C4O3)=C2C([H])=C1[H]
[H]ON([H])C(=O)C1=C([H])N=C2N(N=C(C2=C1N(C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C(C#CC([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C(=N1)N([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(=C(S1)C([H])([H])[H])C1=C([H])C2=C(N([H])C3=C4C(=C5C(=O)N([H])C(=O)C5=C23)C([H])([H])C([H])([H])C4([H])[H])C([H])=C1[H]
[H]O[C@]1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])N([H])C(=O)OC([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C(=O)O[H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C(N([H])C(=O)C2=NC3=C(S2)C([H])([H])N(C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(Cl)S1
OC[C@H](O)COC1=CC2=C(CCC3=C(C=CC(NC4=CC=C(F)C(NC(=O)C5=CC=CC=C5)=C4)=C3)C2=O)C=C1
CCN(CC)C1=CC=C(CN(C2=CC=C(Cl)C=C2)S(=O)(=O)C2=CC(C)=CC=C2)C=C1
[H]N=C(N([H])[H])C([H])([H])C1=C(N(N=C1C(=O)N([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C2=C([H])C([H])=NC(=N2)N2C([H])=NC([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C(=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)N([H])C([H])([H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])S(=O)(=O)C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C(C#N)C(=N1)N([H])C([H])([H])[H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(=NC2=C(C(=NN12)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C1(C2=NC(=NO2)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]1(C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C(=O)N([H])C(=N2)N([H])[H])C(=O)O[H]
[H]N1C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])C2=C1C(=NC([H])=C2[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C([H])([H])C1=C(F)C([H])=C([H])C(F)=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
CC1=CC(OCCCN2C(=CC3=CC=CC=C23)C(O)=O)=CC=C1Cl
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C1=C([H])C([H])=C(O[C@@]2([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C1=NC2=C(C([H])=C([H])C(=C2[H])C(=N[H])N([H])[H])N1C([H])([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC(Cl)=C1C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C1=C(N(C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C12)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C2=C(F)C([H])=C(F)C([H])=C2C([H])([H])C1([H])[H]
[H]N1C(=O)C(=C([H])C(C(=O)O[C@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])SC(=N1)C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C1=NC([H])=C([H])C([H])=C1C1=C2N=C([H])N([H])C2=NC([H])=N1)C1=C([H])C([H])=C([H])C2=C1C([H])=NN2[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C(F)=C2[H])C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])SC1=NC(=C(N1[H])C1=C([H])C([H])=NC(N([H])C([H])([H])[H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
COC1=NC(=NC(C)=C1F)N1C[C@H]2C(=O)N(C)C(=N)N[C@]2(C1)C1=C(F)C=C(F)C=C1F
[H]N1N=C(C2=C(C3=C([H])C(OC([H])([H])[H])=C([H])C(=C3N=C12)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1N2C(=NC(=C(Cl)C2=O)C([H])([H])[H])C([H])=C1C1=C(SC([H])=C1[H])N1C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(=C(Cl)C([H])=C1Cl)C1=NC(=C(N=C1C([H])([H])C([H])([H])[H])N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N(C1=C([H])C([H])=C(Cl)C(=C1Cl)C([H])([H])OC1=C2N=C(C([H])=C(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(O[H])C([H])([H])[C@@]([H])(O[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(C([H])=C(S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)OC([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1OC([H])([H])C([H])([H])O2
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])C([H])([H])N(C(=O)OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]C#CC([H])([H])N1N=NC(=N1)[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])([C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])(C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(\S[H])=N\C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)C(=O)N1C([H])([H])C([H])([H])O[C@@]([H])(C([H])([H])C([H])([H])N([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])N1C(=O)C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H]
[H]N(C1=NC([H])=C(SC2=C([H])C(C(=O)N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])=C(C([H])=C2[H])C([H])([H])[H])S1)C1=NC(Br)=C([H])C([H])=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C2O[C@@]3([H])C4=C(C([H])=C(C([H])=N4)C4=C([H])C([H])=C(Cl)C([H])=C4Cl)C([H])([H])[C@@]4([H])[C@]5([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]OC1=C2C([H])=C([H])C(N([H])C(=O)C3=C([H])C([H])=C(N([H])[H])C([H])=C3[H])=C([H])C2=C([H])C(=C1[H])S(=O)(=O)O[H]
[H]N1C(=C([H])C2=C1C(=O)N(C(=O)N2[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C2C([H])=C([H])C([H])=C([H])C2=NC2=C1[C@@]1([H])C([H])([H])C(=C([H])[C@@]([H])(C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N=C(N1C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])OC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])N(C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])=C12)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C(C([H])=C(\C([H])=C2/SC(=NC2=O)N(OC([H])([H])[H])C([H])([H])[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
CCOC1=CC(=CC=C1Cl)N1CCN(CC1)C(=O)CN1N=C(C(Cl)=C1C)C(F)(F)F
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N1C([H])=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C1=O)C([H])([H])C([H])([H])[H])C(=O)C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(C(=O)N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C(SC2=C([H])C([H])=C([H])C([H])=C2[H])N=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(SC2=NC3=C([H])C([H])=C([H])C([H])=C3C(=N2)N([H])C2=NN([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C4=C(C([H])=C3[H])N(C([H])=C4[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2=C1[H]
CC1CCC\C(C1)=N\NC1=NC(=CS1)C1=CC=CC=C1
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@](N([H])[H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])SSC1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1F
[H]N([C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)[C@@]2([H])C([H])([H])C([H])([H])[C@](N(C(=O)C([H])([H])[H])C([H])([H])[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C(C([H])([H])C(=O)N([H])C1=C([H])C(\C([H])=C(/[H])C2=NC(=C([H])S2)C2([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C2=C(N([H])C(=N2)C2=C([H])C([H])=C(Cl)S2)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])=C(C1=C([H])C([H])=C([H])C(=C1[H])C(N([H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C(=C1[H])C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(\C([H])=C(/[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C(Cl)=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])(C2=NN([H])N=N2)C([H])([H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(=C1F)C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])OC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C(=O)C1([H])[H]
[H]N([C@@]1([H])C(=O)N(C2=C(F)C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)S1
[H]OC1=C([H])C(F)=C(C([H])=C1F)C1=C([H])C([H])=C2C(Cl)=C(O[H])C([H])=C([H])C2=C1[H]
NC1=NC(=CC=N1)N1C=CC2=C1C=CC(=C2)C#N
[H]C1=C([H])N(C(C#CC2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(Cl)=C([H])C([H])=C2O1
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2Cl)=NC(SC([H])([H])C([H])([H])C([H])([H])[H])=N1
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])N(C([H])([H])[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1[H])C(=O)O[H]
[H]C1=C(N(N=C1C(F)(F)F)C1=C([H])C([H])=C(N=[N+]=[N-])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=NC(=C(S1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=C2OC([H])([H])C([H])([H])C2=NC2=C(C(=NN12)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1Cl)C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=NC([H])([H])C(=O)N(C2=C([H])C([H])=C(I)C([H])=C12)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=NO1)C1=C(C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1[H]
C1CC1c1cc(Nc2nc(Nc3ccc4nc[nH]c4c3)nc3ccccc23)[nH]n1
[H]N([H])C1=C([H])C(OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@@]2([H])OC([H])([H])[H]
[H]N(C(=O)N1C(=O)N([H])C2=C(C(=O)OC2([H])[H])[C@]1([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(C(=O)OC([H])([H])[H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C1C1(C([H])([H])N([H])C2=O)C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=NC(=N1)C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])N1C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])S(=O)(=O)C1=C(C2=C([H])C(Cl)=C([H])C([H])=C2S1)C([H])([H])[H]
[H]N1C(=O)N(C(=O)C11C([H])([H])C([H])([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=N2)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])C([H])([H])C(=O)[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H])C([H])([H])C([H])=C([H])[H]
[H]N(C(=O)N1N=C(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
CC1=NN=C2CCC3=C(N12)C(F)=CC(=C3)C1=CN=CC(F)=C1
[H]N(C(=O)OC([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C([H])=C1C1=C2C([H])=C(N([H])C2=NC([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C2=C(O1)C([H])=C(C([H])=C2[H])C(=O)N([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N1C(=O)[C@@]([H])(N2C(=O)OC([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]O[C@]1([H])C2=C(OC(=O)C([H])=C2[C@]2(C([H])([H])[H])[C@@]3([H])[C@]1([H])OC(=O)[C@@]3(C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])[C@@]2([H])O[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=C([H])C([H])=C([H])N=C2[H])=C([H])C([H])=C1[H]
[H]N(C1=C2N=C([H])N(\C([H])=C(/[H])C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C2=NC(=N1)C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])P(=O)(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@]([H])(N([H])[H])C([H])([H])N(C2=C([H])C([H])=NC([H])=C2C([H])([H])C(=O)C2=C([H])C([H])=C(F)C(=N2)C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C(OC([H])([H])C2=C([H])C(OC([H])(F)F)=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
C[Si](C)(C)C#CC1=CC=C(OCCCC2=CNC=N2)C=C1
[H]N1C(=NC2=C3C([H])=C([H])C([H])=C(Br)C3=C3C([H])=C([H])C([H])=C([H])C3=C12)C1=C(F)C([H])=C([H])C([H])=C1Cl
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(N1C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(C(=O)N1\C(SC([H])([H])C1([H])[H])=N\C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NN(C([H])=C1C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C(=O)C3=C([H])C4=C(C([H])=C3[H])C([H])([H])C([H])=N4)C([H])([H])C([H])([H])C([H])([H])[C@]21[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])C1=NC2=C(O1)C([H])=C([H])C(=C2[H])C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])[C@]([H])(N([H])C(=O)C4=C([H])C(I)=C([H])C([H])=C4[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1(N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])C1([H])[H])C([H])([H])OC([H])([H])[H]
[H]C1=C([H])C2=NC(=C([H])C([H])=C2C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C3C(=C([H])C([H])=C2[H])N(C(=O)C([H])([H])C3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(N([H])C(=O)C2=C([H])C([H])=NC([H])=C2[H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C([H])C(=O)N([H])C(=O)N2C([H])([H])C2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@@]2(C(=NN3C4=C([H])C(F)=C([H])C([H])=C4OC([H])([H])[C@@]23[H])C(=O)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])[C@]2([H])[S@@](=O)C([H])([H])[C@@](N([H])[H])(C(=O)O[H])[C@]12[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C2N([H])N=C(\C([H])=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=NC(=C([H])S2)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]OC1=C([H])C(=NC2=C1C([H])=C([H])C(=N2)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C3C(=C([H])C(=O)C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]2([H])[C@]2([H])C([H])([H])C([H])([H])[C@@](O[H])(C#CC([H])([H])[H])[C@@]2(C([H])([H])[H])C1([H])[H])C([H])([H])[H]
CCN1CCN(CC2=NC=C(C=C2)C#C[C@]2(CN3CC4=C(C3=O)C(F)=C(OC)C=C4)CC(=O)NC2=O)CC1
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=O)N(C1=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C([H])([H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=NN([H])N=N1
[H]ON(C(=O)N([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])S1)C([H])([H])[H]
[H]N(C1=C2C(=NC3=C(C(=NN13)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1SC([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C2=C(C([H])=C([H])C([H])=N2)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN(C([H])=N1)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H][C@]12CC[C@]([H])(C[C@H](C1)OC1=CC=CC(=C1)C(N)=O)N2C(C)C1=CC=CC=C1C
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]1([H])C([H])=C([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@]1([H])N([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])O2)C([H])([H])C12N(C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(N2C([H])=C(C(=O)N([H])[H])C(=O)C3=C([H])C([H])=C(C([H])=C23)C2=C([H])C([H])=NC([H])=C2[H])C(F)=C1[H]
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])[C@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N(C([H])([H])C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
CC(C)CC(=S)NCCCC[C@H](NC(=O)[C@H](C)NC(C)=O)C(=O)N[C@@H](C)C(O)=O
[H]C#CC([H])([H])C([H])([H])C([H])([H])N1C(=NC2=C(N=C(F)N=C12)N([H])[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1I
[H]N(C1=NC2=C([H])C([H])=C([H])N=C2N([H])C2=C1C([H])=C(Cl)C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(N2N=C(OC([H])([H])[H])C(N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])OC([H])([H])[C@]34[H])=C2S1)C1=C(OC([H])([H])[H])C([H])=C(C#N)C([H])=C1OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])=C([H])\C(=N/C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C1C([H])=C(Cl)C([H])=C2[H]
[H]C1=NC2=C([H])C([H])=C(C([H])=C2N=C1[H])C1=C(C(=O)N(N1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=NC(=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])OC(=O)C1=C([H])C(O[H])=C(C(=O)C2=C(N([H])S(=O)(=O)C(F)(F)F)C([H])=C([H])C([H])=C2O[H])C(O[H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])SC([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C([H])N=C([H])C([H])=C2[H])=C1[H]
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C2=NN=C3SC([H])([H])C(=NN23)C2=C([H])C(O[C@@]3([H])C([H])([H])OC([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C(F)=C1[H]
[H]OC1=NC2=NC3=C(C([H])=C2N1C([H])([H])[H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])=C3[H]
[H]C1=C([H])C(=O)N(C1=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C(C3=C([H])C(Cl)=C([H])C([H])=C3N2[H])C([H])([H])C1([H])[H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])C([H])([H])C([H])([H])[H])C(=C([H])C(=C1[H])[C@@]1([H])O[C@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C(=O)C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C(N=C2N1C(=O)C(C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])=C(N2C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C(=O)C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[N+]1=C([H])C([H])=C(C([H])=C1[H])N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[N+]1=C([H])C([H])=C(C([H])=C1[H])N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(SC3=C([H])C([H])=C([H])C([H])=C3C(=O)N2C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C2([H])[H]
[H]C1=C(N(C2=C([H])C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C12)C([H])([H])C#N)C(=O)N1C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C(C3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])[C@]([H])(O[H])C([H])([H])[C@]4([H])C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC2=C1N=C([H])N2[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1Cl)[N+]([O-])=O)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C(=O)C4=C([H])C([H])=C(C([H])=C4[H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])O2
[H]OC([H])([H])[C@@]1([H])N(C(=O)[C@]([H])(N([H])S(=O)(=O)C2=C3N([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H]
C[C@@H](NC(=O)C1=CNC2=NC=C(N=C12)C1CC1)C(=O)N1CCC(C1)C#N
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C(/[H])C(=O)N2C([H])([H])C([H])([H])SC([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C2=C3C([H])=C(OC4=C(C#N)C([H])=C([H])C(=C4[H])C([H])([H])N4C([H])=NC([H])=C4C([H])([H])N(C([H])([H])[H])[C@@]([H])(C1=O)C([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C2[H]
[H]C1=NC(C2=C3N=C(C([H])=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1C([H])([H])[H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1O[C@]([H])(C1=NC([H])([H])C([H])([H])N1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C1=C(ON(C([H])([H])[H])[C@@]1([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(\N=C1/C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12)C(=O)C([H])([H])N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])[C@@]1([H])C([H])([H])[C@]([H])(O[C@]2([H])C3=C(O[H])C4=C(C(=O)C5=C([H])C([H])=C([H])C(OC([H])([H])[H])=C5C4=O)C(O[H])=C3C([H])([H])[C@@](O[H])(C(=O)C([H])([H])[H])C2([H])[H])O[C@@]([H])(C([H])([H])[H])[C@@]1([H])O[H]
[H]N(C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(OC(F)(F)F)=C1[H])[C@]1([H])[C@@]([H])(N([H])[C@@]2([H])C([H])([H])OC([H])([H])[C@@]12[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1N=C(C2=NC([H])=C([H])C([H])=C12)C1=C([H])C2=C(N1[H])C([H])=C(C#CC([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])=C2[H]
[H]N(C(=O)C(C1=C([H])N([H])C([H])=N1)(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C(C([H])=C([H])N3C([H])=C([H])N=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=S)SSC(=S)N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
NCCCN1C2=C(C(=O)C3=C2C=CC=C3)C2=CC=C(NCC(O)=O)C=C2C1=O
[H]N1C2=C(C3=C(C([H])=C2[H])C2=C([H])C(F)=C([H])C(F)=C2OC3([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[Cl-].NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CCC1=CC=CC=C1)B(O)O
[H]N(C(=O)C1=C([H])C(OC2=C([H])C3=C(OC(=N3)N([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])=C2[H])=C([H])C([H])=N1)C([H])([H])[H]
[H]N1C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=NC(=NO2)C2=C([H])N(C3=C(Cl)C([H])=C([H])C([H])=C23)C([H])([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C(F)C([H])=C(C([H])=C1[H])C1=C(N=C(O1)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])N([H])C(=O)[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C(N([H])C3=C([H])C([H])([H])C([H])([H])C([H])([H])N3[H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(C(=O)C([H])([H])N1C(Cl)=C([H])N=C(N([H])C([H])([H])C(F)(F)C2=[N+]([O-])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1N=C([H])N=C1[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C(OC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1N=C2C(=C1[H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=NN([H])C2=NN=C(C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C(=O)C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N([H])C(=O)N([H])C1=C(C(=O)N([H])[H])C2=C(S1)C1=C(N(N=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N([H])C(=O)C(=O)[C@]([H])(N([H])C(=O)[C@]1([H])C([H])=C([H])[C@@]([H])(N2N1C(=O)[C@@](N([H])[H])(C2=O)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C(O[H])C([H])=C2[C@]1([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
CCCC1=C(C(=O)OCC)C(C(=O)OCC)=C2N1N=C(C=C2C1=CC=CC=C1)N1CCCC1
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(O[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]OC(C#CC1=C2N=C(N(C2=C(OC([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=N1)C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@](C1=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])[C@@]1([H])C([H])([H])N(C(=O)N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
C[C@@H]1O[C@@H](NS(N)(=O)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O
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[H]C1=NC(=C([H])S1)[C@@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])[C@@]([H])(N(C1=C([H])C(F)=C([H])C([H])=C1F)S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=NC3=C(N=C(N=C3N=C2[H])N([H])[H])N([H])[H])C([H])=C1[H])C(=O)O[H]
CC1(C)OB(OC1(C)C)C1=CC=C(C=C1)C(=O)NCCC1=CC=C(C=C1)S(N)(=O)=O
COC1=CC(=CC=C1)C(=O)NCCN1CCN(CC1)C1=NC=CC=C1C#N
[H]N(C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C2OC3([H])C45C2=C(C([H])=C1[H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])C4([H])[H])C51C([H])=C([H])C3(OC([H])([H])[H])C([H])(C1([H])[H])C(O[H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])O[C@]([H])(C2([H])[H])[C@](O[H])(C2=C([H])C([H])=C([H])C(Cl)=C2C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[C@@]1([H])N([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=NC3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C(Cl)C([H])=C2F)C([H])([H])C1([H])[H]
[H]N([H])C1=NC(N([H])[H])=C(C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]N=C(N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])[C@@]2([H])SC(Br)=C([H])[C@@]2([H])C1([H])[H]
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OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N[C@@H]1CC[Se]C1
[H]N1N=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C(=C2C(=O)O1)C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])OC1=C([H])C(F)=C([H])C2=C1OC([H])([H])C([H])([H])C2=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[P@]1(=O)OC([H])([H])[C@]2([H])O[C@@]([H])(N3C([H])=NC4=C(N=C([H])N=C34)N([H])C([H])([H])[H])C([H])([H])[C@]2([H])O[P@@](=O)(O[H])O[P@@](=O)(O[H])O[P@@](=O)(O[H])O1
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NS(=O)(=O)C1=CN(CC(=O)C2=CC3=CC=CC=C3C=C2)C=CC1=O
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
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[H]N1C2=C(SC3=C2C2=C(N=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])=C3[H])C(=O)N([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
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[H]C1=NC(C2=C3N=C(C([H])=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N3N=C2C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C1=C([H])C(Cl)=C([H])C([H])=C1Cl)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])OC(=O)C([H])([H])[H])C([H])([H])[H]
COC1=CC(=CC=C1Cl)N1CCN(CC1)C(=O)CN1N=C(Br)C(Cl)=C1C
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])N=C1[H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC([H])=C(S1)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N1C([H])=C2C3=C(C([H])=C([H])C([H])=C13)[C@@]1([H])C([H])([H])[C@@]([H])(C([H])([H])SC([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C2([H])[H]
[H]ON(C(=O)C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(C#CC1=NN(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=NC([H])=C(C#CC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=NC(=C([H])C([H])=C2C([H])=N1)C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N1C([H])([H])[H]
[H]O[C@@]([H])(C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(N([H])[H])C([H])([H])OP(=O)(O[H])O[H]
CC1=CC=C2C=C(CN3C=CN=C3)N(C2=C1)C1=CC=C(F)C=C1
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]1(C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(Cl)=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C(S[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C(N([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=NN([H])C2=C([H])C(Cl)=C(C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])C1=NC([H])=NC(OC2=C([H])C(Cl)=C(N([H])C(=O)N([H])C3=NC(=C(S3)C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])=C1\C([H])=N\OC([H])([H])[H]
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])OC([H])([H])C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=O
[H]N(\C(=N/C#N)N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(OC([H])=C2C([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])=C1[H])C([H])([H])N1C([H])=NC2=C([H])C(OC3([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])C([H])=C12
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[H]N([H])[C@@]([H])(C([H])([H])C(=O)N([H])C1(C2=NC3=C(S2)C([H])=C(Cl)C([H])=C3[H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C(C([H])=C1[H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C(\C([H])=C(/[H])C2=C([H])N=C([H])C([H])=C2[H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C(Cl)C([H])=C2[C@]([H])(O[H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C([H])([H])C([H])([H])C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(Br)C([H])=N1
[H]N1C2=C([H])C([H])=C(Br)C([H])=C2C(=N[C@]([H])(OC([H])([H])C([H])([H])[H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@@]([H])(SC([H])([H])C([H])([H])C([O-])=O)C1=C([H])C(OC([H])([H])C2=NC3=C([H])C(Cl)=C([H])C([H])=C3C([H])=C2[H])=C([H])C([H])=C1[H]
[H][C@]12SC=C(N1C(=O)\C2=C\C1=CN2C(SC3=C2C=CC(OC)=C3)=N1)C(=O)O[Na]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(SC2=NC3=C([H])C([H])=C([H])C([H])=C3C(=N2)N([H])C2=C([H])C(=NN2[H])C([H])([H])[H])C([H])=C1[H]
[H]N1N=C(C2=NC(=C([H])N2[H])C(F)(F)F)C(\C([H])=C(/[H])C2=C([H])N=C([H])C3=C([H])C([H])=C([H])C([H])=C23)=C1[H]
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC(=NO1)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([O-])=O
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C2([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C(=O)N([H])C([H])([H])C([H])(N([H])C(=O)C2([H])N(C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C1=O)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C2([H])[H])C(=O)N([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])N(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC([H])=C([H])C([H])=C1[H]
OC(=O)CCCCCC1=CC2=C(OC(=N2)C2=CC(=C(S2)C(F)(F)F)C2=CC=CC=C2)N=C1
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(C2=C([H])C(OC([H])([H])[C@@]3([H])N(C(=O)C([H])([H])[H])C4=C(C([H])=C([H])C([H])=C4[H])C3([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(N([H])S(=O)(=O)C2=C(N([H])C(=O)C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])SC([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(S1)C([H])([H])C([H])([H])C(=O)N([H])C1=NC([H])([H])C([H])([H])C([H])([H])N1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)N(C2=C(C1=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]N(C(=O)C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C(=C(Cl)C([H])=C1[H])C(F)(F)F)C1=NN(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(N=NN2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2F)C(=N1)C1=NC([H])=C([H])O1
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])[C@]([H])(N1C([H])=NC([H])=C1[H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N(C1=NN(C(=N1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])[C@]([H])(OC([H])([H])[C@]1([H])O[H])C(\[H])=C(/[H])[C@]([H])(O[H])C([H])([H])OC1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C(=N[C@](C2=C([H])C([H])=C(F)N=C2[H])(C2=C([H])C([H])=C(F)C([H])=C2[H])[C@]1([H])C([H])([H])[H])C1=C(F)N([H])C(=O)C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(=NN1C([H])([H])C(=O)N1C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C1C(=O)N2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=CC(OC(CC2=CC=CC=C2)C(O)=O)=CC(C)=C1C1=CC=CC=C1
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[H]N(C(=O)C1=C(Cl)C([H])=NC([H])=C1Cl)C([H])([H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@]([H])(OC1=NC([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=O)C2=C([H])C(F)=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])[H])C([H])([H])N([H])C2=C([H])C(OC([H])([H])[H])=C([H])C(=C2[H])C(F)(F)F)=N1
[H]C1=C(C([H])=C(C([H])=C1C(F)(F)F)C(F)(F)F)C(=O)C(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])N(C(=O)[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=NN=C2SC([H])([H])C(=NN12)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F
[H]OC1=C(N([H])C2=C(N([H])[C@@]([H])(C3=C([H])C(=C([H])O3)C([H])([H])[H])[C@@]([H])(F)C([H])([H])[H])C(=O)C2=O)C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])[C@]([H])(N(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CS)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)[C@H](CS)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(O)=O
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[H]O\C(=C(\C#N)C(=O)N([H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C(F)(F)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C([H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]O[C@](C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C(=C([H])C(=C1[H])C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])[C@]([H])(SC1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])N1C2=C(C([H])=C(I)C([H])=C2[H])C2=C1C(=S)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
OCC1=CC=CC(=N1)C#CC1=CC=CC(=C1)C#N
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])[C@]2(O[C@@]([H])(C#N)C([H])([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N1C(=O)N([H])C2(C3=C([H])C(Cl)=C(Cl)C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])[C@]1([H])C([H])([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C1[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C(N([H])C2=C(C(=O)N([H])C2=O)C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C(Cl)=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C2=C(S1)C([H])=C(O[H])C([H])=C2[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(C([H])([H])C#C[H])C([H])([H])C1=NC2=C(N=C(N=C2N=C1[H])N([H])[H])N([H])[H])C(=O)O[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])N1N=NC(=C1[H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H]
[H]\C(=C1\S\C(=N/C([H])([H])[H])N(C1=O)C([H])([H])[H])C1=C(N(C(=C1[H])C([H])([H])[H])C1=NC([H])=C([H])C([H])=C1F)C([H])([H])[H]
[H]C1=C([H])C([H])=C(S1)C1=C([H])N=C(OC([H])([H])C([H])([H])OC2=NC([H])=NC([N-]S(=O)(=O)C3=C([H])C([H])=C(C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])N=C1[H]
[H]N1C([H])([H])C(=O)N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])[C@@]([H])(C([H])([H])OC([H])([H])C2=C([H])C(Cl)=C(C([H])=C2[H])C([H])([H])[H])C1([H])[H]
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[H]N(N([H])C(=O)C1=C(Cl)C2=C([H])C([H])=C([H])C([H])=C2S1)C(\[H])=C1/C(Cl)=NC2=C([H])C([H])=C([H])C([H])=C12
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[H]OC([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C([H])C2=C1N(C([H])([H])C1=C(N=C(C([H])=C1[H])C(F)(F)F)N2[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])[C@]([H])(N([H])C(=O)C(\[H])=C(/[H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])[C@@]4(OC(=O)C([H])([H])[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
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[H]N([H])[C@@]1([H])\C(=N/OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
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[H]N(C(=O)C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=C1C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C([H])C([H])=C([H])C([H])=C4N=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
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[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=C(N=C([H])C(=N1)N([H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=N1)C([H])([H])[H])C([H])([H])[H]
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[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N2C(=NN=C2C(F)(F)F)[C@@]1([H])C([H])([H])C(F)(F)F)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]OC1=C([H])N=C([H])C(=C1[H])C(=O)N([H])C1(C(=O)N([H])[C@@]([H])(C2=C(F)C([H])=C(C([H])=C2[H])N2N=C(Cl)C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H]
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[H]N([H])C(=O)C([H])([H])N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C(\[H])=C1\C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@]2([H])SC(=C([H])[C@]2([H])C1([H])[H])[N+]([O-])=O
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C2=C(N([H])N=C2[H])C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC(C2=C([H])C([H])=C([H])C(F)=C2[H])=C(C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
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[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(S1)C([H])=C([H])C(N([H])[H])=C2[H]
[H]C1=C([H])N=C(S1)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)OC([H])([H])[H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
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[H]N(C(=O)N([H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N1C(=NC2=C([H])C(Cl)=C(C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)C1(C([H])([H])[H])C([H])([H])C([H])([H])C(=O)C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(N=C(N2C2=NC(=NC(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])(F)F)C(OC([H])([H])C([H])([H])[H])=C1[H]
NC(=O)N1C(=O)\C(=C(/O)C2=CC=CS2)C2=C1C=CC(Cl)=C2
[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])P(=O)(OC1=C([H])C([H])=C([H])C([H])=C1[H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C(N([H])[C@]([H])(C(=O)O[H])[C@]3([H])C([H])([H])C([H])=C([H])[C@]23[H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C(C(OC([H])([H])[H])=C1[H])C(F)(F)F
[H]N=C(N(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=N1
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[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
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[H]C1=NC([H])=C(N1C([H])([H])[H])[C@]([H])(OC([H])([H])C1=C2N=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C#N)C(=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])N3C(=O)C([H])([H])C4(C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3=O)C([H])([H])C2([H])[H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]OC(=O)[C@@]([H])(OC1=NC(=C([H])C(=N1)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=C(F)C(C)=NC(=N1)N1C[C@H]2C(=O)N(C)C(=N)N[C@]2(C1)C1=CC=CC(=C1)C#N
[H]C1=NC2=C(C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3OC([H])([H])[H])[N+]([O-])=C([H])C([H])=C2C(=C1[H])C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
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[H]N1C(=O)OC(C2=C([H])C(=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2N([H])C([H])=C([H])C2=C1C([H])([H])[H])C1=C(C#N)C([H])=NC([H])=C1\C([H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])O[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])O[C@@]([H])(C([H])([H])C(=O)C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=NC([H])=C([H])C5=C4C([H])([H])C([H])([H])O5)C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C([H])=C([H])C(=O)O[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=NC(=O)C([H])([H])S1
[H]C1=C([H])C([H])=C([H])C(=N1)[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])[C@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C(S1)N(C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N2N=NC3=C2N=C(N=C3OC([H])(C([H])([H])OC([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])[H])C(Br)=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(N=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(F)C([H])=C2F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1(C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(C#N)(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(N=C(N=C2O[C@@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])N1C1=C([H])C([H])=C(C([H])=C1Br)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C2=NOC(=C2Cl)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C1([H])[H]
[H]OC(=O)[C@]1([H])[C@@]([H])(SC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])N([H])N=N2)C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1N=NC2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]C([H])=C([H])[C@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C([H])([H])N(C1=C([H])C([H])=C(C#N)C(Cl)=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C1=C(C([H])=C2[H])C(=O)N([H])C([H])([H])C1([H])[H]
[H]N(S(=O)(=O)C1=C([H])C([H])=C([H])S1)S(=O)(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1(C([H])([H])N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)N2C([H])=NN=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N3C([H])([H])C([H])([H])N(C([H])([H])C4=NOC(=C4[H])C([H])([H])[H])C([H])([H])C3([H])[H])C(Br)=C([H])N=C2N1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C(=O)C2=C(O1)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N(C(=O)C([H])([H])N([H])C(=O)C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
COC1=CC(CN(CCO)C(=O)NC2=CC=C(C=C2)C2=CNN=C2)=CC=C1
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(OC2=C(F)C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N([H])C([H])([H])[H]
[H]N(C#N)C(\OC1=C([H])C([H])=C([H])C([H])=C1[H])=N/C([H])([H])C1=C([H])C([H])=C([H])C(\N=C(/N([H])C#N)N([H])C2=C([H])C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C2[H])=C1[H]
[H]C1=C([H])C([H])=C(OC2=C([H])C([H])=C(F)C([H])=C2N(C(=O)C([H])([H])[H])C([H])([H])C2=C(OC([H])([H])F)C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])=C1[H]
[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[N+]2([O-])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C(=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=NC(F)=C(C([H])=C1[H])[C@]1([H])C([H])([H])C2=C(N=NC2=C2N=NN=N2)C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(SC(=C2C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C(=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])[H])=NC([H])=N1
[H]N([H])C1=NC(N([H])[H])=C2C(=N1)N([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])SC1=NN=C([H])N1C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]N1C2=NC([H])=C([H])C(C3=C(N=C(N3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C([H])C([H])=C(F)C([H])=C3[H])=C2C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N1C(=O)C2=C([H])C([H])=C(C([H])=C2C1([H])[H])N(C([H])([H])[H])C([H])([H])C1=NC2=C(N=C(N=C2N=C1[H])N([H])[H])N([H])[H])C(=O)O[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(S[H])N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N([H])C([H])([H])[C@]1([H])O[C@]([H])(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C(=O)C1=C([H])C2=C(C([H])=C([H])C([H])=C2S1)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]2(OC(=O)C3=C([H])C([H])=NC([H])=C23)C([H])([H])C1([H])[H])C1=C([H])N(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C(I)N(C2=C1C([H])=C(OC([H])([H])[H])C(=C2[H])[N+]([O-])=O)C([H])([H])[H]
[H]OC1=C(S\C(N([H])[H])=C(/C#N)\C(\C#N)=C(\SC2=C(O[H])C([H])=C([H])C([H])=C2[H])N([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=C([H])C(SC2=C([H])N=C(S2)N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(N([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C3C(=NC([H])=C2[H])N([H])C([H])=C13)C(=O)OC([H])([H])[H]
[H]N(C(=O)C([H])([H])SC1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1C2=O
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NOC([H])=C2C(=C([H])C([H])=C12)C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NN([H])C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C(=O)N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])N=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C(=C(C([H])=C1OC([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(O[C@@]([H])(C([H])([H])O[P@@](=O)(OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N([H])[H])N([H])C3=O)C([H])([H])[C@]1([H])O[P@](=O)(OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=C(C(=O)N([H])C2=O)C([H])([H])[H])C([H])([H])[C@]1([H])O[P@@](=O)(OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N([H])[H])N([H])C3=O)C([H])([H])[C@]1([H])O[P@@](=O)(OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N([H])[H])N([H])C3=O)C([H])([H])[C@]1([H])O[P@@](=O)(OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=C(C(=O)N([H])C2=O)C([H])([H])[H])C([H])([H])[C@]1([H])O[P@@](=O)(OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=C(C(=O)N([H])C2=O)C([H])([H])[H])C([H])([H])[C@]1([H])O[P@@](=O)(OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N([H])[H])N([H])C3=O)C([H])([H])[C@]1([H])O[P@](=O)(OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N([H])[H])N([H])C3=O)C([H])([H])[C@]1([H])O[H])N([H])[H])N([H])[H])N([H])[H])N([H])[H])N([H])[H])N([H])[H])N([H])[H])N([H])[H])C([H])([H])O[P@](=O)(O[C@@]1([H])C([H])([H])[C@@]([H])(O[C@]1([H])C([H])([H])O[P@](=O)(O[C@]1([H])C([H])([H])[C@]([H])(O[C@@]1([H])N1C([H])=NC2=C1N=C(N([H])[H])N([H])C2=O)C([H])([H])O[P@](=O)(O[C@@]1([H])C([H])([H])[C@@]([H])(O[C@]1([H])C([H])([H])O[P@](=O)(O[C@@]1([H])C([H])([H])[C@@]([H])(O[C@]1([H])C([H])([H])O[P@](=O)(O[C@@]1([H])C([H])([H])[C@@]([H])(O[C@]1([H])C([H])([H])O[P@](=O)(O[C@@]1([H])C([H])([H])[C@@]([H])(O[C@]1([H])C([H])([H])O[H])N1C([H])=NC2=C1N=C(N([H])[H])N([H])C2=O)N([H])[H])N1C([H])=NC2=C1N=C(N([H])[H])N([H])C2=O)N([H])[H])N1C([H])=C(C(=O)N([H])C1=O)C([H])([H])[H])N([H])[H])N1C([H])=C(C(=O)N([H])C1=O)C([H])([H])[H])N([H])[H])N([H])[H])N1C([H])=NC2=C1N=C(N([H])[H])N([H])C2=O)N([H])[H])N1C([H])=C([H])C(=O)N([H])C1=O
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])C(=N[H])N([H])[H]
[H]C1=C([H])C2=C(N=C1Cl)C(C1=C(C([H])=C(Cl)C([H])=C1[H])C([H])([H])C2([H])[H])=C1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC2=C(C([H])=C([H])C(=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1=O
[H]N1C(SC([H])([H])C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(C([H])=C(N=N1)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C2=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])C([H])([H])[H])C1(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[18F])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])C1=C([H])SC(=N1)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])=C1[H])C([H])([H])N1C(=NC2=C([H])C(=C([H])C([H])=C12)N(C([H])([H])[C@@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C(=O)C1=C(N2N=C([H])C(=C([H])C2=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])[H]
[H]N([C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C3=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])N=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(C([H])=N1)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C(Br)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(\C([H])=C1/C(=O)N([H])C(=O)C2=C([H])C([H])=C(C([H])=C12)C1=C([H])SC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[O-]C(=O)C([O-])=O